+D Receptor KO
#
G Protein-Coupled Receptors - Malurus melanocephalus (red-backed fairy wren)
%
!
ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
D 130585981 CHRM2; muscarinic acetylcholine receptor M2 K04130 CHRM2; muscarinic acetylcholine receptor M2
D 130572334 CHRM3; muscarinic acetylcholine receptor M3 K04131 CHRM3; muscarinic acetylcholine receptor M3
D 130573025 CHRM4; muscarinic acetylcholine receptor M4 K04132 CHRM4; muscarinic acetylcholine receptor M4
D 130578761 CHRM5; muscarinic acetylcholine receptor M5 K04133 CHRM5; muscarinic acetylcholine receptor M5
C Adrenaline
D 130584633 ADRA1A; alpha-1A adrenergic receptor K04135 ADRA1A; adrenergic receptor alpha-1A
D 130583408 ADRA1B; alpha-1B adrenergic receptor K04136 ADRA1B; adrenergic receptor alpha-1B
D 130575423 ADRA1D; alpha-1D adrenergic receptor K04137 ADRA1D; adrenergic receptor alpha-1D
D 130582103 ADRA2A; alpha-2A adrenergic receptor K04138 ADRA2A; adrenergic receptor alpha-2A
D 130580786 alpha-2C adrenergic receptor-like K04140 ADRA2C; adrenergic receptor alpha-2C
D 130573092 ADRA2C; alpha-2C adrenergic receptor K04140 ADRA2C; adrenergic receptor alpha-2C
D 130575972 ADRB1; beta-1 adrenergic receptor K04141 ADRB1; adrenergic receptor beta-1
D 130585537 beta-2 adrenergic receptor-like K04142 ADRB2; adrenergic receptor beta-2
D 130586471 ADRB3; beta-3 adrenergic receptor K04143 ADRB3; adrenergic receptor beta-3
C Dopamine
D 130580814 DRD1; D(1A) dopamine receptor K04144 DRD1; dopamine receptor D1
D 130583281 DRD2; D(2) dopamine receptor K04145 DRD2; dopamine receptor D2
D 130572495 DRD3; D(3) dopamine receptor K04146 DRD3; dopamine receptor D3
D 130581682 DRD4; D(4) dopamine receptor K04147 DRD4; dopamine receptor D4
D 130582597 D(1)-like dopamine receptor K05840 DRD5; dopamine receptor D5
D 130577874 DRD5; D(1B) dopamine receptor K05840 DRD5; dopamine receptor D5
C Dopamine and ecdysteroid
C Histamine
D 130586011 HRH1; histamine H1 receptor K04149 HRH1; histamine receptor H1
D 130580805 HRH2; histamine H2 receptor K04150 HRH2; histamine receptor H2
D 130589246 octopamine receptor-like K04150 HRH2; histamine receptor H2
D 130581706 HRH3; histamine H3 receptor K04151 HRH3; histamine receptor H3
D 130579108 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 130574180 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 130574187 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
C Octopamine and tryamine
C Serotonin
D 130575410 HTR1B; 5-hydroxytryptamine receptor 1B K04153 HTR1; 5-hydroxytryptamine receptor 1
D 130581895 HTR1D; 5-hydroxytryptamine receptor 1D K04153 HTR1; 5-hydroxytryptamine receptor 1
D 130582157 HTR1E; 5-hydroxytryptamine receptor 1E K04153 HTR1; 5-hydroxytryptamine receptor 1
D 130588740 HTR1A; 5-hydroxytryptamine receptor 1A K04153 HTR1; 5-hydroxytryptamine receptor 1
D 130588915 HTR1F; 5-hydroxytryptamine receptor 1F K04153 HTR1; 5-hydroxytryptamine receptor 1
D 130577353 HTR2C; 5-hydroxytryptamine receptor 2C K04157 HTR2; 5-hydroxytryptamine receptor 2
D 130582797 HTR2A; 5-hydroxytryptamine receptor 2A K04157 HTR2; 5-hydroxytryptamine receptor 2
D 130574151 HTR2B; 5-hydroxytryptamine receptor 2B K04157 HTR2; 5-hydroxytryptamine receptor 2
D 130583530 HTR4; 5-hydroxytryptamine receptor 4 K04160 HTR4; 5-hydroxytryptamine receptor 4
D 130576416 HTR5A; 5-hydroxytryptamine receptor 5A K04161 HTR5; 5-hydroxytryptamine receptor 5
D 130573797 5-hydroxytryptamine receptor 5A-like K04161 HTR5; 5-hydroxytryptamine receptor 5
D 130584768 HTR6; LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 6 K04162 HTR6; 5-hydroxytryptamine receptor 6
D 130575470 5-hydroxytryptamine receptor 7-like K04163 HTR7; 5-hydroxytryptamine receptor 7
D 130576354 HTR7; 5-hydroxytryptamine receptor 7 isoform X1 K04163 HTR7; 5-hydroxytryptamine receptor 7
C Trace amine
D 130572574 TAAR2; LOW QUALITY PROTEIN: trace amine-associated receptor 2 K05051 TAAR; trace amine associated receptor
D 130572594 TAAR1; trace amine-associated receptor 1 K05051 TAAR; trace amine associated receptor
B Peptide
C Adrenomedullin (G10D)
D 130586335 GPR182; G-protein coupled receptor 182 K04242 ADMR; adrenomedullin receptor
C Adropin
D 130577817 LOW QUALITY PROTEIN: probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
D 130577826 probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
C Apelin
D 130581650 APLNR; apelin receptor K04174 APLNR; apelin receptor
C Anaphylatoxin
D 130579206 C3AR1; LOW QUALITY PROTEIN: C3a anaphylatoxin chemotactic receptor K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
C Angiotensin
D 130580393 AGTR1; type-1 angiotensin II receptor K04166 AGTR1; angiotensin II receptor type 1
D 130582673 AGTR2; type-2 angiotensin II receptor K04167 AGTR2; angiotensin II receptor type 2
C BigLEN
C Bombesin
D 130576347 NMBR; neuromedin-B receptor K04168 NMBR; neuromedin B receptor
D 130578778 GRPR; gastrin-releasing peptide receptor K04169 GRPR; gastrin-releasing peptide receptor
C Bradykinin
D 130576906 BDKRB1; B1 bradykinin receptor K03915 BDKRB1; bradykinin receptor B1
D 130576905 BDKRB2; B2 bradykinin receptor K03916 BDKRB2; bradykinin receptor B2
C Cholecystokinin
D 130572976 CCKAR; cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor
D 130582719 CCKBR; gastrin/cholecystokinin type B receptor K04195 CCKBR; cholecystokinin B receptor
C Endothelin
D 130575344 EDNRA; endothelin-1 receptor K04197 EDNRA; endothelin receptor type A
D 130578709 endothelin receptor type B-like K04198 EDNRB; endothelin receptor type B
D 130573790 EDNRB; endothelin receptor type B K04198 EDNRB; endothelin receptor type B
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
D 130577360 FSHR; follicle-stimulating hormone receptor K04247 FSHR; follicle stimulating hormone receptor
C Galanin
D 130572691 galanin receptor type 1-like K04230 GALR1; galanin receptor 1
D 130573840 GALR1; galanin receptor type 1 K04230 GALR1; galanin receptor 1
D 130581070 GALR2; galanin receptor type 2 K04231 GALR2; galanin receptor 2
D 130587132 GALR3; galanin receptor type 3 isoform X1 K04232 GALR3; galanin receptor 3
C Ghrelin
D 130575495 GHSR; growth hormone secretagogue receptor type 1 K04284 GHSR; growth hormone secretagogue receptor
C Gonadotropin-releasing hormone (GnRH)
D 130585612 gonadotropin-releasing hormone II receptor-like K04280 GNRHR; gonadotropin-releasing hormone receptor
D 130577156 gonadotropin-releasing hormone II receptor-like K04280 GNRHR; gonadotropin-releasing hormone receptor
C Lutropin-choriogonadotropic hormone
D 130585341 LHCGR; LOW QUALITY PROTEIN: lutropin-choriogonadotropic hormone receptor K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
C Melanin-concentrating hormone (MCH)
D 130582584 melanin-concentrating hormone receptor 1-like K04320 MCHR1; melanin-concentrating hormone receptor 1
D 130572421 MCHR2; LOW QUALITY PROTEIN: melanin-concentrating hormone receptor 2 K05054 MCHR2; melanin-concentrating hormone receptor 2
C Melanocortin
D 130585169 MC2R; adrenocorticotropic hormone receptor K04200 MC2R; melanocortin 2 receptor
D 130582175 MC3R; melanocortin receptor 3 K04201 MC3R; melanocortin 3 receptor
D 130577647 MC4R; melanocortin receptor 4 K04202 MC4R; melanocortin 4 receptor
D 130585168 MC5R; melanocortin receptor 5 isoform X1 K04203 MC5R; melanocortin 5 receptor
C Motilin
D 130574257 MLNR; motilin receptor K05266 MLNR; motilin receptor
C Neuromedin U
D 130574147 NMUR1; neuromedin-U receptor 1 K05052 NMUR1; neuromedin U receptor 1
D 130586117 NMUR2; neuromedin-U receptor 2 K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D 130582423 NPFFR1; LOW QUALITY PROTEIN: neuropeptide FF receptor 1 K04240 NPFFR1; neuropeptide FF receptor 1
C Neuropeptide S
D 130574457 NPSR1; neuropeptide S receptor isoform X1 K08376 NPSR1; neuropeptide S receptor
C Neuropeptide W / neuropeptide B
D 130574842 NPBWR1; neuropeptides B/W receptor type 1 K05268 NPBWR1; neuropeptides B/W receptor 1
D 130573582 NPBWR2; neuropeptides B/W receptor type 2 K08377 NPBWR2; neuropeptides B/W receptor 2
C Neuropeptide Y
D 130578837 NPY1R; neuropeptide Y receptor type 1 K04204 NPY1R; neuropeptide Y receptor type 1
D 130579264 NPY2R; neuropeptide Y receptor type 2 K04205 NPY2R; neuropeptide Y receptor type 2
D 130579344 neuropeptide Y receptor type 2-like K04205 NPY2R; neuropeptide Y receptor type 2
D 130576391 NPY4R2; neuropeptide Y receptor type 4-2 K04206 NPY4R; neuropeptide Y receptor type 4
D 130578831 NPY5R; neuropeptide Y receptor type 5 K04207 NPY5R; neuropeptide Y receptor type 5
D 130577978 neuropeptide Y receptor type 6-like K04208 NPY6R; neuropeptide Y receptor type 6
D 130582364 G-protein coupled receptor 83-like K04210 GPR83; G protein-coupled receptor 83
D 130582366 G-protein coupled receptor 83-like K04210 GPR83; G protein-coupled receptor 83
D 130578137 GPR83; G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
C Neurotensin
D 130581707 neurotensin receptor type 1-like K04211 NTSR1; neurotensin receptor 1
C Opioid
D 130586233 OPRD1; delta-type opioid receptor K04213 OPRD1; delta-type opioid receptor
D 130574849 OPRK1; kappa-type opioid receptor K04214 OPRK1; kappa-type opioid receptor
D 130572876 OPRM1; mu-type opioid receptor K04215 OPRM1; mu-type opioid receptor
D 130573584 OPRL1; nociceptin receptor K04216 OPRL1; nociceptin receptor
C Orexigenic neuropeptide QRFP
D 130582083 QRFPR; pyroglutamylated RF-amide peptide receptor K08378 QRFPR; pyroglutamylated RFamide peptide receptor
C Orexin
D 130577082 HCRTR2; orexin receptor type 2 K04239 HCRTR2; hypocretin (orexin) receptor 2
C Oxytocin
D 130585467 OXTR; oxytocin receptor K04229 OXTR; oxytocin receptor
C Prokineticin
D 130575261 prokineticin receptor 2-like K08380 PROKR2; prokineticin receptor 2
C Prolactin-releasing peptide (PrRP)
D 130582762 PRLHR; prolactin-releasing peptide receptor K04314 PRLHR; prolactin releasing hormone receptor
D 130583364 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
C Prosaposin
D 130580885 GPR37; prosaposin receptor GPR37 K04243 GPR37; prosaposin receptor
D 130585941 GPR37L1; G-protein coupled receptor 37-like 1 K04244 GPR37L1; prosaposin receptor
C Relaxin
D 130578876 RXFP1; relaxin receptor 1 K04306 RXFP1; relaxin family peptide receptor 1
D 130572756 RXFP3; relaxin-3 receptor 1 K08397 RXFP3; relaxin family peptide receptor 3
C Somatostatin
D 130574823 SSTR1; somatostatin receptor type 1 K04217 SSTR1; somatostatin receptor 1
D 130583682 SSTR2; somatostatin receptor type 2 K04218 SSTR2; somatostatin receptor 2
D 130585932 SSTR3; somatostatin receptor type 3 K04219 SSTR3; somatostatin receptor 3
D 130582656 SSTR4; somatostatin receptor type 4 isoform X1 K04220 SSTR4; somatostatin receptor 4
D 130584866 SSTR5; somatostatin receptor type 5 K04221 SSTR5; somatostatin receptor 5
C Tachykinin
D 130586763 substance-P receptor-like isoform X1 K04222 TACR1; tachykinin receptor 1
D 130578000 TACR2; substance-K receptor isoform X1 K04223 TACR2; tachykinin receptor 2
D 130581234 TACR3; neuromedin-K receptor K04224 TACR3; tachykinin receptor 3
C Thrombin
D 130572260 F2R; proteinase-activated receptor 1 K03914 F2R; coagulation factor II (thrombin) receptor
D 130572261 F2RL1; proteinase-activated receptor 2 K04234 F2RL1; coagulation factor II (thrombin) receptor-like 1
D 130572259 F2RL2; proteinase-activated receptor 3 K04235 F2RL2; coagulation factor II (thrombin) receptor-like 2
D 130584884 F2RL3; LOW QUALITY PROTEIN: proteinase-activated receptor 4 K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
C Thyrotropin
D 130582572 TSHR; thyrotropin receptor isoform X1 K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
D 130579173 TRHR; thyrotropin-releasing hormone receptor K04282 TRHR; thyrotropin-releasing hormone receptor
C Urotensin II
D 130587058 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 130578168 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 130578177 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
C Vasopressin
D 130579851 AVPR1A; vasopressin V1a receptor K04226 AVPR1A; arginine vasopressin receptor 1A
D 130585758 AVPR1B; vasopressin V1b receptor K04227 AVPR1B; arginine vasopressin receptor 1B
D 130573593 arg8-vasotocin receptor-like K04228 AVPR2; arginine vasopressin receptor 2
C Neuropeptide receptors
B Chemokine
C CC Chemokine
D 130580037 CCR4; C-C chemokine receptor type 4 K04179 CCR4; C-C chemokine receptor type 4
D 130580033 C-C chemokine receptor type 1-like K04180 CCR5; C-C chemokine receptor type 5
D 130580034 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 130584567 CCR6; C-C chemokine receptor type 6 K04181 CCR6; C-C chemokine receptor type 6
D 130585414 CCR7; C-C chemokine receptor type 7 K04182 CCR7; C-C chemokine receptor type 7
D 130580029 C-C chemokine receptor type 4-like K04183 CCR8; C-C chemokine receptor type 8
D 130580032 C-C chemokine receptor type 8-like K04183 CCR8; C-C chemokine receptor type 8
D 130580039 CCR9; C-C chemokine receptor type 9 K04184 CCR9; C-C chemokine receptor type 9
D 130581435 CCR10; C-C chemokine receptor type 10 K04185 CCR10; C-C chemokine receptor type 10
D 130587252 atypical chemokine receptor 1-like K06574 ACKR1; atypical chemokine receptor 1
D 130576321 ACKR2; LOW QUALITY PROTEIN: atypical chemokine receptor 2 K04187 ACKR2; atypical chemokine receptor 2
D 130580024 ACKR4; atypical chemokine receptor 4 K04186 ACKR4; atypical chemokine receptor 4
D 130583000 GPR75; probable G-protein coupled receptor 75 K08417 GPR75; G protein-coupled receptor 75
C CXC Chemokine
D 130572808 C-X-C chemokine receptor type 2-like isoform X1 K05050 CXCR2; C-X-C chemokine receptor type 2
D 130573817 CXCR4; C-X-C chemokine receptor type 4 K04189 CXCR4; C-X-C chemokine receptor type 4
D 130581113 CXCR5; C-X-C chemokine receptor type 5 K04190 CXCR5; C-X-C chemokine receptor type 5
D 130588895 ACKR3; atypical chemokine receptor 3 K04304 CXCR7; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
D 130580157 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 130580160 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 130580164 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
C CX3C Chemokine
D 130580027 CX3CR1; CX3C chemokine receptor 1 K04192 CX3CR1; CX3C chemokine receptor 1
C C Chemokine
D 130580030 XCR1; chemokine XC receptor 1 K04193 XCR1; XC chemokine receptor 1
C Chemokine like
D 130580516 CMKLR1; chemerin-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 130582523 chemerin-like receptor 1 isoform X1 K04245 CMKLR1; chemokine-like receptor 1
D 130577470 CMKLR2; chemerin-like receptor 2 K04310 GPR1; G protein-coupled receptor 1
D 130572427 GPR15; G-protein coupled receptor 15 K08403 GPR15; G protein-coupled receptor 15
B Base and nucleoside
C Purine / pyrimidine
D 130586824 P2RY1; P2Y purinoceptor 1 K04270 P2RY1; P2Y purinoceptor 1
D 130573431 P2Y purinoceptor 1-like K04270 P2RY1; P2Y purinoceptor 1
D 130574749 P2RY2; P2Y purinoceptor 2 K04269 P2RY2; P2Y purinoceptor 2
D 130586371 P2RY4; P2Y purinoceptor 4 K04271 P2RY4; P2Y purinoceptor 4
D 130574750 P2RY6; P2Y purinoceptor 6 isoform X1 K04272 P2RY6; P2Y purinoceptor 6
D 130577916 P2RY8; P2Y purinoceptor 8 K08386 P2RY8; P2Y purinoceptor 8
D 130586956 P2Y purinoceptor 13-like K08388 P2RY13; P2Y purinoceptor 13
D 130588662 SUCNR1; succinate receptor 1 K10042 SUCNR1; succinate receptor 1
C Adenosine
D 130578338 ADORA1; adenosine receptor A1 K04265 ADORA1; adenosine receptor A1
D 130578040 ADORA2A; adenosine receptor A2a K04266 ADORA2A; adenosine receptor A2a
D 130576951 ADORA2B; adenosine receptor A2b K04267 ADORA2B; adenosine receptor A2b
D 130586110 ADORA3; adenosine receptor A3 K04268 ADORA3; adenosine receptor A3
B Lipid
C Arachidonylglycine
D 130573634 GPR18; N-arachidonyl glycine receptor K08410 GPR18; N-arachidonyl glycine receptor
C Bile acid
C Cysteinyl leukotriene
D 130582821 CYSLTR1; cysteinyl leukotriene receptor 1 K04322 CYSLTR1; cysteinyl leukotriene receptor 1
D 130574255 CYSLTR2; cysteinyl leukotriene receptor 2 K04323 CYSLTR2; cysteinyl leukotriene receptor 2
C Free fatty acid
D 130581211 FFAR4; free fatty acid receptor 4 K08425 FFAR4; free fatty acid receptor 4
C HETE and oxoETE
C Leukotriene
D 130572724 leukotriene B4 receptor 1-like K04296 LTB4R1; leukotriene B4 receptor 1
C Lysophosphatidic acid
D 130572919 LPAR1; lysophosphatidic acid receptor 1 K04289 LPAR1; lysophosphatidic acid receptor 1
D 130578536 LPAR3; lysophosphatidic acid receptor 3 K04294 LPAR3; lysophosphatidic acid receptor 3
D 130582822 LPAR4; lysophosphatidic acid receptor 4 K04275 LPAR4; lysophosphatidic acid receptor 4
D 130574773 LPAR5; lysophosphatidic acid receptor 5 K08390 LPAR5; lysophosphatidic acid receptor 5
D 130574253 LPAR6; lysophosphatidic acid receptor 6 K04273 LPAR6; lysophosphatidic acid receptor 6
D 130586954 G-protein coupled receptor 87-like K08389 GPR87; G protein-coupled receptor 87
C Lysophosphatidylinositol
D 130580159 G-protein coupled receptor 55-like K08413 GPR55; G protein-coupled receptor 55
C Lysophosphatidylserine
D 130582296 GPR34; probable G-protein coupled receptor 34 K08383 GPR34; G protein-coupled receptor 34
D 130582818 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 130582823 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 130582813 GPR174; probable G-protein coupled receptor 174 K08391 GPR174; G protein-coupled receptor 174
C Oleoylethanolamide
D 130578724 GPR119; glucose-dependent insulinotropic receptor K08424 GPR119; glucose-dependent insulinotropic receptor
C Prostaglandin
D 130585683 PTGDR; prostaglandin D2 receptor K04332 PTGDR; prostaglandin D2 receptor
D 130585684 PTGER2; prostaglandin E2 receptor EP2 subtype K04259 PTGER2; prostaglandin E receptor 2
D 130587102 PTGER3; prostaglandin E2 receptor EP3 subtype K04260 PTGER3; prostaglandin E receptor 3
D 130572787 PTGER4; prostaglandin E2 receptor EP4 subtype K04261 PTGER4; prostaglandin E receptor 4
D 130578726 PTGFR; prostaglandin F2-alpha receptor isoform X1 K04262 PTGFR; prostaglandin F receptor
C Prostacyclin
C Sphingolipid
D 130572552 S1PR1; sphingosine 1-phosphate receptor 1 K04288 S1PR1; sphingosine 1-phosphate receptor 1
D 130588509 S1PR2; sphingosine 1-phosphate receptor 2 K04292 S1PR2; sphingosine 1-phosphate receptor 2
D 130584657 S1PR3; sphingosine 1-phosphate receptor 3 K04290 S1PR3; sphingosine 1-phosphate receptor 3
D 130580237 S1PR4; sphingosine 1-phosphate receptor 4 K04293 S1PR4; sphingosine 1-phosphate receptor 4
C Thromboxane
D 130579784 TBXA2R; thromboxane A2 receptor K04264 TBXA2R; thromboxane A2 receptor
B Vision
C Opsin
D 130583623 RHO; rhodopsin K04250 RHO; rhodopsin
D 130585046 green-sensitive opsin K04250 RHO; rhodopsin
D 130587507 OPN1SW; short-wave-sensitive opsin 1 K04252 OPN1SW; short wavelength-sensitive opsin
D 130576998 pinopsin-like K04251 OPN1LW; long/medium wavelength-sensitive opsin
D 130575545 pinopsin-like K04256 OPN3; c-opsin
D 130572336 OPN3; opsin-3 K04256 OPN3; c-opsin
D 130580168 pinopsin-like K04256 OPN3; c-opsin
D 130576619 OPN4; melanopsin K04255 OPN4; r-opsin
D 130573825 melanopsin-like K04255 OPN4; r-opsin
D 130580821 LOW QUALITY PROTEIN: opsin-5-like K08385 OPN5; G0-opsin
D 130585342 opsin-5-like K08385 OPN5; G0-opsin
D 130576233 RRH; visual pigment-like receptor peropsin K04253 RRH; visual pigment-like receptor peropsin
D 130576627 RGR; RPE-retinal G protein-coupled receptor K04254 RGR; retinal G protein coupled receptor
B Others
C Alpha-ketoglutarate
D 130573624 OXGR1; 2-oxoglutarate receptor 1 K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
C Cannabinoid
D 130583099 CNR1; cannabinoid receptor 1 K04277 CNR1; cannabinoid receptor 1
C Estrogen
D 130581621 GPER1; G-protein coupled estrogen receptor 1 K04246 GPER1; G-protein coupled estrogen receptor 1
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
D 130587470 probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139
D 130587921 probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139
D 130583700 GPR142; probable G-protein coupled receptor 142 isoform X1 K08430 GPR142; G protein-coupled receptor 142
C Mas proto-oncogene and Mas-related (MRGs)
D 130572578 MAS1; proto-oncogene Mas K04303 MAS1; proto-oncogene Mas
C Melatonin
D 130575961 MTNR1A; melatonin receptor type 1A K04285 MTNR1A; melatonin receptor type 1A
D 130578937 GPR50; melatonin-related receptor isoform X1 K04285 MTNR1A; melatonin receptor type 1A
D 130579246 MTNR1B; melatonin receptor type 1B K04286 MTNR1B; melatonin receptor type 1B
C Oxysterol
D 130573622 G-protein coupled receptor 183-like K04305 EBI2; Epstein-Barr virus induced gene 2
D 130573632 GPR183; G-protein coupled receptor 183 isoform X1 K04305 EBI2; Epstein-Barr virus induced gene 2
C Platelet activating factor
D 130581885 PTAFR; platelet-activating factor receptor K04279 PTAFR; platelet-activating factor receptor
C Proton-sensing GPCRs
D 130583688 GPR65; psychosine receptor K08416 GPR65; psychosine receptor
D 130576165 GPR68; ovarian cancer G-protein coupled receptor 1 K08408 GPR68; ovarian cancer G-protein coupled receptor 1
D 130579646 GPR132; probable G-protein coupled receptor 132 K08426 GPR132; G protein-coupled receptor 132
C R-spondin
D 130581591 LGR4; leucine-rich repeat-containing G-protein coupled receptor 4 K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
D 130580344 LGR5; leucine-rich repeat-containing G-protein coupled receptor 5 K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
D 130578342 LGR6; leucine-rich repeat-containing G-protein coupled receptor 6 K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
C Super conserved receptor expressed in brain (SREB)
D 130573738 GPR27; probable G-protein coupled receptor 27 K04301 SREB1; super conserved receptor expressed in brain 1
D 130589238 GPR85; probable G-protein coupled receptor 85 K04302 SREB2; super conserved receptor expressed in brain 2
C Trissin
C Orphan GPCRs / unclassified GPCRs
D 130584643 GPR3; G-protein coupled receptor 3 K04311 GPR3; G protein-coupled receptor 3
D 130589020 GPR6; G-protein coupled receptor 6 K04313 GPR6; G protein-coupled receptor 6
D 130575923 G-protein coupled receptor 12-like K04315 GPR12; G protein-coupled receptor 12
D 130573876 GPR12; G-protein coupled receptor 12 K04315 GPR12; G protein-coupled receptor 12
D 130586437 GPR17; uracil nucleotide/cysteinyl leukotriene receptor K08404 GPR17; G protein-coupled receptor 17
D 130575094 GPR20; G-protein coupled receptor 20 K04317 GPR20; G protein-coupled receptor 20
D 130577510 GPR21; probable G-protein coupled receptor 21 K04318 GPR21; G protein-coupled receptor 21
D 130572680 GPR22; G-protein coupled receptor 22 K04319 GPR22; G protein-coupled receptor 22
D 130573071 GPR78; G-protein coupled receptor 78 K08411 GPR26; G protein-coupled receptor 26
D 130583500 GPR26; G-protein coupled receptor 26 K08411 GPR26; G protein-coupled receptor 26
D 130573804 GPR39; G-protein coupled receptor 39 K08412 GPR39; G protein-coupled receptor 39
D 130582570 GPR52; G-protein coupled receptor 52 K08407 GPR52; G protein-coupled receptor 52
D 130578597 probable G-protein coupled receptor K08414 GPR61; G protein-coupled receptor 61
D 130578872 GPR61; G-protein coupled receptor 61 K08414 GPR61; G protein-coupled receptor 61
D 130572416 GPR63; probable G-protein coupled receptor 63 K04321 GPR63; G protein-coupled receptor 63
D 130582297 GPR82; probable G-protein coupled receptor 82 K08420 GPR82; G protein-coupled receptor 82
D 130572511 GPR88; probable G-protein coupled receptor 88 K08422 GPR88; G protein-coupled receptor 88
D 130582504 GPR135; G-protein coupled receptor 135 K08427 GPR135; G protein-coupled receptor 135
D 130579861 probable G-protein coupled receptor 141 K08429 GPR141; G protein-coupled receptor 141
D 130581614 GPR146; probable G-protein coupled receptor 146 K08431 GPR146; G protein-coupled receptor 146
D 130578293 GPR148; probable G-protein coupled receptor 148 K08432 GPR148; G protein-coupled receptor 148
D 130583817 GPR149; probable G-protein coupled receptor 149 K08433 GPR149; G protein-coupled receptor 149
D 130575489 GPR160; probable G-protein coupled receptor 160 K08438 GPR160; G protein-coupled receptor 160
D 130572468 GPR161; G-protein coupled receptor 161 K08439 GPR161; G protein-coupled receptor 161
D 130574785 GPR162; probable G-protein coupled receptor 162 K08440 GPR162; G protein-coupled receptor 162
D 130578762 GPR176; G-protein coupled receptor 176 K08442 GPR176; G protein-coupled receptor 176
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ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
D 130582581 calcitonin receptor-like K04576 CALCR; calcitonin receptor
D 130583830 CALCRL; calcitonin gene-related peptide type 1 receptor K04577 CALCRL; calcitonin receptor-like
C Parathyroid hormone
D 130582471 parathyroid hormone/parathyroid hormone-related peptide receptor-like K04585 PTH1R; parathyroid hormone receptor 1
D 130574553 PTH1R; parathyroid hormone/parathyroid hormone-related peptide receptor isoform X1 K04585 PTH1R; parathyroid hormone receptor 1
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
D 130583466 CRHR1; corticotropin-releasing factor receptor 1 K04578 CRHR1; corticotropin releasing hormone receptor 1
D 130576316 CRHR2; corticotropin-releasing factor receptor 2 K04579 CRHR2; corticotropin releasing hormone receptor 2
C Growth hormone-releasing hormone (GHRH)
D 130576325 GHRHR; growth hormone-releasing hormone receptor K04584 GHRHR; growth hormone releasing hormone receptor
B Pancreatic peptide
C Glucagon
D 130575800 GLP1R; LOW QUALITY PROTEIN: glucagon-like peptide 1 receptor K04581 GLP1R; glucagon-like peptide 1 receptor
D 130578183 GLP2R; glucagon-like peptide 2 receptor K04582 GLP2R; glucagon-like peptide 2 receptor
D 130582005 GCGR; glucagon receptor K04583 GCGR; glucagon receptor
D 130577229 glucagon receptor-like K04583 GCGR; glucagon receptor
B Gut peptide
C Gastric inhibitory peptide (GIP)
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
D 130576312 VIPR1; vasoactive intestinal polypeptide receptor 1 K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 130576322 vasoactive intestinal polypeptide receptor 1-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 130582664 VIPR2; vasoactive intestinal polypeptide receptor 2 K04590 VIPR2; vasoactive intestinal peptide receptor 2
D 130576314 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
C Secretin
D 130579731 SCTR; secretin receptor K04588 SCTR; secretin receptor
B Others
C Receptor activity modifying protein
D 130581466 RAMP2; receptor activity-modifying protein 2 K08448 RAMP2; receptor activity modifying protein 2
D 130574317 RAMP3; receptor activity-modifying protein 3 isoform X1 K08449 RAMP3; receptor activity modifying protein 3
C Methuselah-like proteins (MTH)
C Pigment dispersing factor (PDF)
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AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
C 130575862 CELSR1; cadherin EGF LAG seven-pass G-type receptor 1 isoform X1 K04600 CELSR1; cadherin EGF LAG seven-pass G-type receptor 1
C 130578359 CELSR2; cadherin EGF LAG seven-pass G-type receptor 2 isoform X1 K04601 CELSR2; cadherin EGF LAG seven-pass G-type receptor 2
C 130589080 CELSR3; cadherin EGF LAG seven-pass G-type receptor 3 K04602 CELSR3; cadherin EGF LAG seven-pass G-type receptor 3
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
B Latrophilin
C 130578679 ADGRL2; adhesion G protein-coupled receptor L2 isoform X1 K04593 ADGRL2; adhesion G protein-coupled receptor L2
C 130573956 ADGRL3; adhesion G protein-coupled receptor L3 isoform X1 K04594 ADGRL3; adhesion G protein-coupled receptor L3
C 130578715 ADGRL4; adhesion G protein-coupled receptor L4 isoform X1 K04595 ADGRL4; adhesion G protein-coupled receptor L4
B Brain-specific angiogenesis inhibitor (BAI)
C 130575117 adhesion G protein-coupled receptor B3 isoform X1 K04598 ADGRB3; adhesion G protein-coupled receptor B3
B Others
C 130582304 adhesion G protein-coupled receptor A3-like K08460 ADGRA1; adhesion G protein-coupled receptor A1
C 130586470 ADGRA2; adhesion G protein-coupled receptor A2 K08461 ADGRA2; adhesion G protein-coupled receptor A2
C 130572992 ADGRA3; adhesion G protein-coupled receptor A3 K08462 ADGRA3; adhesion G protein-coupled receptor A3
C 130585789 LOW QUALITY PROTEIN: adhesion G-protein coupled receptor D1-like K08465 ADGRD1; adhesion G-protein coupled receptor D1
C 130577490 ADGRD2; adhesion G-protein coupled receptor D2 K08466 ADGRD2; adhesion G-protein coupled receptor D2
C 130580818 ADGRF4; adhesion G protein-coupled receptor F4 isoform X1 K08457 ADGRF4; adhesion G-protein coupled receptor F4
C 130580817 ADGRF5; adhesion G protein-coupled receptor F5 isoform X1 K08458 ADGRF5; adhesion G-protein coupled receptor F5
C 130579494 ADGRG1; adhesion G-protein coupled receptor G1 K08450 ADGRG1; adhesion G-protein coupled receptor G1
C 130586658 adhesion G-protein coupled receptor G2-like K08451 ADGRG2; adhesion G-protein coupled receptor G2
C 130579530 LOW QUALITY PROTEIN: adhesion G protein-coupled receptor G3-like K08452 ADGRG3; adhesion G-protein coupled receptor G3
C 130572842 ADGRG6; adhesion G-protein coupled receptor G6 isoform X1 K08463 ADGRG6; adhesion G-protein coupled receptor G6
C 130572431 ADGRG7; LOW QUALITY PROTEIN: adhesion G-protein coupled receptor G7 K08464 ADGRG7; adhesion G-protein coupled receptor G7
C 130577548 ADGRV1; adhesion G-protein coupled receptor V1 K18263 ADGRV1; adhesion G-protein coupled receptor V1
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AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C 130572359 GRM1; metabotropic glutamate receptor 1 isoform X1 K04603 GRM1; metabotropic glutamate receptor 1
C 130578616 GRM2; metabotropic glutamate receptor 2 K04605 GRM2; metabotropic glutamate receptor 2
C 130573749 GRM3; metabotropic glutamate receptor 3 K04606 GRM3; metabotropic glutamate receptor 3
C 130582645 metabotropic glutamate receptor 4 K04607 GRM4; metabotropic glutamate receptor 4
C 130577941 GRM5; metabotropic glutamate receptor 5 K04604 GRM5; metabotropic glutamate receptor 5
C 130586450 metabotropic glutamate receptor 6-like K04608 GRM6; metabotropic glutamate receptor 6
C 130584651 metabotropic glutamate receptor 7-like K04609 GRM7; metabotropic glutamate receptor 7
C 130580614 metabotropic glutamate receptor 8-like K04610 GRM8; metabotropic glutamate receptor 8
B GABA
C 130575509 gamma-aminobutyric acid type B receptor subunit 2-like K04615 GABBR; gamma-aminobutyric acid type B receptor
C 130579445 GPR156; probable G-protein coupled receptor 156 K04617 GPR156; gamma-aminobutyric acid type B receptor-like
B Calcium-sensing
C 130582284 CASR; extracellular calcium-sensing receptor K04612 CASR; calcium-sensing receptor
C 130575215 GPRC6A; G-protein coupled receptor family C group 6 member A K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
B Orphan GPRC5
C 130581870 retinoic acid-induced protein 3-like K08468 GPRC5A; G protein-coupled receptor family C group 5 member A
C 130587285 G-protein coupled receptor family C group 5 member B-like K04619 GPRC5B; G protein-coupled receptor family C group 5 member B
C 130587488 G-protein coupled receptor family C group 5 member B-like K04619 GPRC5B; G protein-coupled receptor family C group 5 member B
C 130583692 GPRC5C; G-protein coupled receptor family C group 5 member C isoform X1 K04620 GPRC5C; G protein-coupled receptor family C group 5 member C
B Unclassified GPCRs
C 130584211 GPR158; probable G-protein coupled receptor 158 K08469 GPR158; G protein-coupled receptor 158
#
AFrizzled / Smoothened family
B 130579146 FZD7; frizzled-7 K02432 FZD1_7; frizzled 1/7
B 130579748 FZD1; frizzled-1 K02432 FZD1_7; frizzled 1/7
B 130583666 FZD2; frizzled-2 K02235 FZD2; frizzled 2
B 130586851 frizzled-3 K02329 FZD3; frizzled 3
B 130577947 FZD4; frizzled-4 K02354 FZD4; frizzled 4
B 130576452 FZD8; frizzled-8 K02375 FZD5_8; frizzled 5/8
B 130582803 FZD5; frizzled-5 K02375 FZD5_8; frizzled 5/8
B 130577246 FZD6; frizzled-6 K02376 FZD6; frizzled 6
B 130583734 FZD10; frizzled-10 K02842 FZD9_10; frizzled 9/10
B 130574603 FZD9; frizzled-9 K02842 FZD9_10; frizzled 9/10
B 130587096 SMO; protein smoothened K06226 SMO; smoothened
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AOthers
B Chemoreception
C Olfactory
D 130581431 olfactory receptor 10C1-like K04257 OLFR; olfactory receptor
D 130581439 olfactory receptor 10A7-like K04257 OLFR; olfactory receptor
D 130586681 olfactory receptor 4D1-like K04257 OLFR; olfactory receptor
D 130586683 olfactory receptor 10A7-like K04257 OLFR; olfactory receptor
D 130586685 olfactory receptor 49-like K04257 OLFR; olfactory receptor
D 130581447 olfactory receptor 6Y1-like K04257 OLFR; olfactory receptor
D 130581451 olfactory receptor 6B1-like K04257 OLFR; olfactory receptor
D 130586967 olfactory receptor 6F1-like isoform X1 K04257 OLFR; olfactory receptor
D 130588356 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 130588596 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 130588599 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 130588603 olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 130582721 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 130582725 olfactory receptor 52R1-like K04257 OLFR; olfactory receptor
D 130582727 olfactory receptor 51G2-like K04257 OLFR; olfactory receptor
D 130582728 olfactory receptor 51G2-like K04257 OLFR; olfactory receptor
D 130582729 olfactory receptor 51E2-like K04257 OLFR; olfactory receptor
D 130582743 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 130582746 LOW QUALITY PROTEIN: olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 130582747 LOW QUALITY PROTEIN: olfactory receptor 52I2-like K04257 OLFR; olfactory receptor
D 130574815 olfactory receptor 10AC1-like K04257 OLFR; olfactory receptor
D 130580073 olfactory receptor 1509-like K04257 OLFR; olfactory receptor
D 130580078 olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 130580079 olfactory receptor 5V1-like K04257 OLFR; olfactory receptor
C Taste
D 130579062 TAS1R1; taste receptor type 1 member 1 K04624 TAS1R1; taste receptor type 1 member 1
D 130587371 TAS1R3; taste receptor type 1 member 3 K04626 TAS1R3; taste receptor type 1 member 3
D 130580822 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
D 130580823 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 130588207 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 130588450 taste receptor type 2 member 7-like K08474 TAS2R; taste receptor type 2
D 130588458 taste receptor type 2 member 116-like K08474 TAS2R; taste receptor type 2
D 130572367 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 130578968 taste receptor type 2 member 114-like K08474 TAS2R; taste receptor type 2
D 130578986 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
D 130578988 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
D 130574817 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 130574818 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 130574819 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
C Vomeronasal pheromone
C Insect odorant and taste
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D 130588824 GPR143; G-protein coupled receptor 143 K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D 130581776 GPR107; protein GPR107 K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
C Bacterial rhodopsin
C Orphan GPCRs
D 130589099 TPRA1; transmembrane protein adipocyte-associated 1 K22988 TPRA1; transmembrane protein adipocyte-associated 1
D 130585680 GPR137C; integral membrane protein GPR137C K22989 GPR137; integral membrane protein GPR137
D 130588792 GPR137B; integral membrane protein GPR137B K22989 GPR137; integral membrane protein GPR137
D 130579301 GPR157; G-protein coupled receptor 157 K08467 GPR157; G protein-coupled receptor 157
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
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Classification taken and modified from GPCRDB