+C Lipid biosynthesis protein KO #

  Lipid Biosynthesis Proteins - Mycobacterium tuberculosis variant microti

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AFatty acid synthase B Animal type B Yeast type B Bacteria type C RN08_2799 fatty acid synthase K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-] B Component type C RN08_0724 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C RN08_2491 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C RN08_0274 3-oxoacyl-ACP reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C RN08_1511 3-oxoacyl-ACP reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C RN08_1791 acyl-CoA thioesterase TesB K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] C RN08_2886 acyl-CoA thioesterase TesB K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] C RN08_0596 3-oxoacyl-[acyl-carrier-protein] synthase III K11608 mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier protein] synthase III [EC:2.3.1.301] C RN08_2493 3-oxoacyl-ACP synthase 1 K11609 kasA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase I [EC:2.3.1.293] C RN08_2494 3-oxoacyl-ACP synthase 2 K27070 kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294] C RN08_1662 3-oxoacyl-ACP reductase FabG1 K11610 mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-] C RN08_0710 (3R)-hydroxyacyl-ACP dehydratase subunit HadA K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadA [EC:4.2.1.-] C RN08_0711 (3R)-hydroxyacyl-ACP dehydratase subunit HadB K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadB [EC:4.2.1.-] C RN08_0712 (3R)-hydroxyacyl-ACP dehydratase subunit HadC K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-] C RN08_0563 hypothetical protein K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadD [EC:4.2.1.-] C RN08_1663 NADH-dependent enoyl-[ACP] reductase K11611 inhA; meromycolic acid enoyl-[acyl-carrier protein] reductase [EC:1.3.1.118] # ADesaturase B First C RN08_0920 acyl-ACP desaturase DesA K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26] C RN08_1229 acyl-ACP desaturase DesA K03922 desA2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.-] C RN08_3566 stearoyl-CoA 9-desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-] B Omega B Front-end B Sphingolipid B Other # AElongase B LCFA B PUFA B Unclassified # APolyketide synthase B Modular PKS C RN08_3240 multifunctional mycocerosic acid synthase K11628 mas; mycocerosic acid synthase [EC:2.3.1.111] C RN08_3249 polyketide synthase K12430 pks1_15; 4-hydroxyphenylalkanoate synthase [EC:2.3.1.261] C RN08_4223 phthioceranic/hydroxyphthioceranic acid synthase K12431 pks2; phthioceranic/hydroxyphthioceranic acid synthase [EC:2.3.1.287] C RN08_2269 polyketide synthase K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295] C RN08_4194 polyketide synthase K12437 pks13; polyketide synthase 13 C RN08_3228 phthiocerol synthesis polyketide synthase type I PpsA K12440 ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292] C RN08_3230 phthiocerol synthesis polyketide synthase type I PpsB K12441 ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292] C RN08_3232 phthiocerol synthesis polyketide synthase type I PpsC K12442 ppsC; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292] C RN08_3233 phthiocerol synthesis polyketide synthase type I PpsD K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292] C RN08_3234 phthiocerol synthesis polyketide synthase type I PpsE K12444 ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292] B Component type C RN08_2641 polyketide synthetase K04790 mbtC; mycobactin polyketide synthetase MbtC C RN08_2640 polyketide synthetase K04791 mbtD; mycobactin polyketide synthetase MbtD # AAcyl-CoA ligase B Short/medium chain acyl-CoA ligase C RN08_4043 acetyl-CoAsynthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] B Long/very long chain acyl-CoA ligase C RN08_2425 long-chain-fatty-acid--CoA ligase FadD15 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C RN08_1865 bifunctional long-chain acyl-CoA synthase/lipase K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-] C RN08_1337 fatty-acid--CoA ligase FadD36 K12429 fadD36; fatty acid CoA ligase FadD36 B Unknown C RN08_2871 fatty-acid--CoA ligase FadD9 K12421 fadD9; fatty acid CoA ligase FadD9 C RN08_1329 fatty-acid--CoA ligase FadD21 K12423 fadD21; fatty acid CoA ligase FadD21 C RN08_0189 fatty-acid--CoA ligase FadD5 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_0617 fatty-acid--CoA ligase FadD8 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_1132 polyketide synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_1349 fatty-acid--CoA ligase FadD6 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_1944 fatty-acid--CoA ligase FadD1 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_2139 fatty-acid--CoA ligase FadD31 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_2776 fatty-acid--CoA ligase FadD35 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C RN08_3864 long-chain-fatty-acid--CoA ligase FadD17 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] # AAcyl-AMP ligase B Fatty acyl-AMP ligase (FAAL) C RN08_0116 fatty-acid--CoA ligase FadD10 K12422 fadD10; medium/long-chain-fatty-acid---[acyl-carrier-protein] ligase FadD10 [EC:6.2.1.-] C RN08_4224 long-chain-fatty-acid--CoA ligase FadD23 K12425 fadD23; long-chain fatty acid adenylase/transferase FadD23 [EC:6.2.1.57] C RN08_3227 fatty-acid--CoA ligase FadD26 K12426 fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:6.2.1.59] C RN08_3241 long-chain-fatty-acid--AMP ligase FadD28 K12427 fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:6.2.1.49] C RN08_3252 long-chain-fatty-acid--AMP ligase FadD29 K21059 fadD29; 4-hydroxyphenylalkanoate adenylyltransferase [EC:6.2.1.51] C RN08_4195 long-chain-fatty-acid--AMP ligase FadD32 K12428 fadD32; fatty acyl-AMP ligase FadD32 [EC:6.2.1.-] B Aryl-AMP ligase C RN08_3250 p-hydroxybenzoyl--AMP ligase K12424 fadD22; 4-hydroxybenzoate adenylyltransferase [EC:6.2.1.50] # APhospholipid acyltransferase B GPAT C RN08_1738 acyltransferase PlsB K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] C RN08_2747 glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] B LPAAT/LPLAT C RN08_2419 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] # AOthers B Multifunctional type C RN08_1325 polyketide beta-ketoacyl synthase K12432 pks3_4; mycolipanoate synthase [EC:2.3.1.252] C RN08_1714 polyketide synthase K12433 pks5; polyketide synthase 5 C RN08_1843 polyketide synthase K12435 pks8; polyketide synthase 8 C RN08_1844 polyketide synthase K12439 pks17; polyketide synthase 17 B Component type C RN08_3255 trans-acting enoyl reductase K12445 K12445; trans enoyl reductase [EC:1.3.1.-] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: December 11, 2024 #
Desaturase/elongase family classification based on Hashimoto et al. (2008)