+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Candidatus Methylospira mobilis
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ACRISPR-Cas system
B Universal Cas proteins
C F6R98_00825 cas1e; type I-E CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
C F6R98_05460 cas1c; type I-C CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
C F6R98_21205 cas1f; type I-F CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
C F6R98_00830 type I-E CRISPR-associated endoribonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
C F6R98_05465 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
B Type I CRISPR-Cas system
C Type I signiture cas proteins
D F6R98_00775 cas3; CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D F6R98_05425 cas3; CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D F6R98_21200 cas3f; type I-F CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
C Subtype I-A factors
D F6R98_05455 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
C Subtype I-B factors
D F6R98_05455 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
C Subtype I-C factors
D F6R98_05435 cas8c; type I-C CRISPR-associated protein Cas8c/Csd1 K19117 csd1; CRISPR-associated protein Csd1
D F6R98_05440 cas7c; type I-C CRISPR-associated protein Cas7/Csd2 K19118 csd2; CRISPR-associated protein Csd2
D F6R98_05455 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D F6R98_05430 cas5c; type I-C CRISPR-associated protein Cas5 K19119 cas5d; CRISPR-associated protein Cas5d
C Subtype I-D factors
D F6R98_05455 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
C Subtype I-E factors
D F6R98_00780 casA; type I-E CRISPR-associated protein Cse1/CasA K19123 casA; CRISPR system Cascade subunit CasA
D F6R98_00785 casB; type I-E CRISPR-associated protein Cse2/CasB K19046 casB; CRISPR system Cascade subunit CasB
D F6R98_00790 cas7e; type I-E CRISPR-associated protein Cas7/Cse4/CasC K19124 casC; CRISPR system Cascade subunit CasC
D F6R98_00795 cas5e; type I-E CRISPR-associated protein Cas5/CasD K19125 casD; CRISPR system Cascade subunit CasD
D F6R98_00800 cas6e; type I-E CRISPR-associated protein Cas6/Cse3/CasE K19126 casE; CRISPR system Cascade subunit CasE
C Subtype I-F factors
D F6R98_21180 csy1; type I-F CRISPR-associated protein Csy1 K19127 csy1; CRISPR-associated protein Csy1
D F6R98_21175 csy2; type I-F CRISPR-associated protein Csy2 K19128 csy2; CRISPR-associated protein Csy2
D F6R98_21165 cas6f; type I-F CRISPR-associated endoribonuclease Cas6/Csy4 K19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-]
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
D F6R98_05455 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C F6R98_02970 DEAD/DEAH box helicase K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C F6R98_15975 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C F6R98_19445 restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C F6R98_19935 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C F6R98_02940 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C F6R98_15965 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C F6R98_19450 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C F6R98_19925 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C F6R98_02965 SAM-dependent DNA methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C F6R98_15950 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C F6R98_18785 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C F6R98_19460 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C F6R98_19910 SAM-dependent DNA methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D F6R98_01365 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D F6R98_10370 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D F6R98_13605 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
C F6R98_08605 restriction endonuclease subunit R K01156 res; type III restriction enzyme [EC:3.1.21.5]
C F6R98_08610 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
B Type IV R-M system
C F6R98_19465 restriction endonuclease K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
C SymE-SymR
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
C ChpB-ChpS
C YhaV-PrlF
C RelE/StbE-RelB/StbD
C YafQ-dinJ
C YoeB-YefM
D F6R98_04270 Txe/YoeB family addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D F6R98_04275 type II toxin-antitoxin system Phd/YefM family antitoxin K19159 yefM; antitoxin YefM
C HipA-HipB
C HicA-HicB
D F6R98_16870 mRNA interferase K07339 hicA; mRNA interferase HicA [EC:3.1.-.-]
D F6R98_16865 type II toxin-antitoxin system HicB family antitoxin K18843 hicB; antitoxin HicB
C YafO-YafN
C PspC-PspB
C CcdB-CcdA
C ParE-ParD
D F6R98_02040 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
D F6R98_12805 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4
C Doc-Phd
C HigB-HigA
D F6R98_01415 peptidase K07334 higB-1; toxin HigB-1
D F6R98_08645 peptidase K07334 higB-1; toxin HigB-1
D F6R98_16285 peptidase K07334 higB-1; toxin HigB-1
D F6R98_19895 ImmA/IrrE family metallo-endopeptidase K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D F6R98_00755 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D F6R98_01420 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D F6R98_08640 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
D F6R98_16280 HigA family addiction module antidote protein K21498 higA-1; antitoxin HigA-1
C MqsR-MqsA
C VapC-VapB
D F6R98_18050 type II toxin-antitoxin system VapC family toxin K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D F6R98_18045 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18829 mvpT; antitoxin VapB
D F6R98_21275 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K18829 mvpT; antitoxin VapB
D F6R98_16670 type II toxin-antitoxin system VapC family toxin K28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-]
D F6R98_16665 type II toxin-antitoxin system prevent-host-death family antitoxin K28280 vapB22; antitoxin VapB22
D F6R98_18090 type II toxin-antitoxin system prevent-host-death family antitoxin K28280 vapB22; antitoxin VapB22
D F6R98_15795 type II toxin-antitoxin system VapC family toxin K28143 vapC24S; ribonuclease VapC24/25/29/31/33/37/38/39/41/43/44/48 [EC:3.1.-.-]
D F6R98_15800 DUF2191 domain-containing protein K28144 vapB24S; antitoxin VapB24/25/29/31/33/37/38/39/41/43/44/48
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
C BC_0920-BC_0921
C SpoIISA-SpoIISB
C Tse6-Tsi6
C Type II TA system related factors
D F6R98_04875 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D F6R98_01640 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D F6R98_16300 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D F6R98_17355 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D F6R98_08585 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
C CptA-CptB
D F6R98_12105 hypothetical protein K19168 cptA; toxin CptA
D F6R98_12110 hypothetical protein K09159 cptB; antitoxin CptB
C AbiEii-AbiEi
B Type V TA system
C GhoT-GhoS
C Other GhoT/OrtT toxin family protein
B Type VI TA system
C SocB-SocA
B Type VII TA system
C Hha-TomB
C TglT-TakA
C HepT-MntA
B Type VIII TA system
C SdsR-RyeA
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ADNA phosphothiolation system
B Sulfur modification proteins
C F6R98_03695 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C F6R98_18240 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C F6R98_01995 hypothetical protein K19171 dndD; DNA sulfur modification protein DndD
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 19, 2025