+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Monoraphidium neglectum
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
C Adherin complex
C CTF18-RFC complex
D MNEG_10704 sister chromatid cohesion protein DCC1 K11271 DSCC1; sister chromatid cohesion protein DCC1
D MNEG_8127 replication factor C subunit 2/4 K10755 RFC2_4; replication factor C subunit 2/4
D MNEG_5877 Replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D MNEG_4777 Replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
C Other sister chromatid cohesion factors
D MNEG_12401 putative ATP-dependent RNA helicase DDX11 K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D MNEG_2596 hypothetical protein K20793 NAA50; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
C Synaptonemal complex
C DSB formation-related proteins
D MNEG_6430 ataxia telangectasia mutated family protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D MNEG_10677 meiotic recombination protein SPO11 K10878 SPO11; meiotic recombination protein SPO11
C Others
D MNEG_4167 hypothetical protein K15271 HFM1; ATP-dependent DNA helicase HFM1/MER3 [EC:5.6.2.4]
D MNEG_1555 DNA mismatch repair protein MSH4 K08740 MSH4; DNA mismatch repair protein MSH4
B Nucleosome assembly factors
C Histones
D MNEG_3378 hypothetical protein K11275 H1_5; histone H1/5
D MNEG_0048 hypothetical protein K11275 H1_5; histone H1/5
D MNEG_9390 hypothetical protein K11251 H2A; histone H2A
D MNEG_7225 putative histone H2A variant 1 K11251 H2A; histone H2A
D MNEG_11378 Histone H2A K11251 H2A; histone H2A
D MNEG_7100 Histone H2A K11251 H2A; histone H2A
D MNEG_16474 Histone H2A K11251 H2A; histone H2A
D MNEG_4391 Histone H2AX K11251 H2A; histone H2A
D MNEG_4317 Histone H2A K11251 H2A; histone H2A
D MNEG_5343 Histone H2A K11251 H2A; histone H2A
D MNEG_6878 Histone H3 K11253 H3; histone H3
D MNEG_8952 Histone H3 K11253 H3; histone H3
D MNEG_2118 Histone H3.3a K11253 H3; histone H3
D MNEG_15785 Histone H4 K11254 H4; histone H4
D MNEG_9389 Histone H4 K11254 H4; histone H4
D MNEG_12546 Histone H4 K11254 H4; histone H4
D MNEG_7102 Histone H4 K11254 H4; histone H4
D MNEG_8106 Histone H4 K11254 H4; histone H4
D MNEG_16427 Histone H4 K11254 H4; histone H4
D MNEG_4318 Histone H4 K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
E MNEG_1311 Putative nucleosome assembly protein K11279 NAP1L1; nucleosome assembly protein 1-like 1
E MNEG_9525 Putative nucleosome assembly protein K11279 NAP1L1; nucleosome assembly protein 1-like 1
E MNEG_5328 Protein SET K11290 SET; template-activating factor I
D CAF-1
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D FACT complex
E MNEG_5261 hypothetical protein K09272 SSRP1; FACT complex subunit SSRP1/POB3
E MNEG_14447 FACT complex subunit SPT16, putative K25639 SUPT16H; FACT complex subunit SPT16
D Other Histone chaperones and regulators
E MNEG_8610 Histone chaperone asf1 K10753 ASF1; histone chaperone ASF1
E MNEG_11573 putative Uncharacterized protein C15orf41 like protein K24865 CDIN1; CDAN1-interacting nuclease 1
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
D MNEG_5207 Histone acetyltransferase type B catalytic subunit K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D MNEG_7909 E1A/CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D MNEG_10416 E1A/CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D MNEG_12050 Transcription initiation factor TFIID subunit 1 K23358 TAF1; transcription initiation factor TFIID subunit 1, fungi type [EC:2.3.1.48]
D MNEG_0786 histone acetyltransferase MYST1 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D MNEG_7341 hypothetical protein K22767 MCC1; histone acetyltransferase MCC1 [EC:2.3.1.48]
C HAT complexes
D PCAF complex
E MNEG_1322 Transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E MNEG_0603 hypothetical protein K03134 TAF10; transcription initiation factor TFIID subunit 10
E MNEG_0683 Transcription initiation factor TFIID subunit12 K03126 TAF12; transcription initiation factor TFIID subunit 12
D STAGA complex
E MNEG_1322 Transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E MNEG_0603 hypothetical protein K03134 TAF10; transcription initiation factor TFIID subunit 10
E MNEG_0683 Transcription initiation factor TFIID subunit12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E MNEG_10532 Splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
E MNEG_16182 Splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
D TFTC complex
E MNEG_11275 transcription initiation factor TFIID subunit D2 K03128 TAF2; transcription initiation factor TFIID subunit 2
E MNEG_1322 Transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E MNEG_0603 hypothetical protein K03134 TAF10; transcription initiation factor TFIID subunit 10
E MNEG_0683 Transcription initiation factor TFIID subunit12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E MNEG_10532 Splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
E MNEG_16182 Splicing factor 3B subunit 3 K12830 SF3B3; splicing factor 3B subunit 3
D TIP60 complex
E MNEG_0450 DNA methyltransferase 1-associated protein K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
E MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
E MNEG_3085 putative Protein AF-9 like protein K11341 YEATS4; YEATS domain-containing protein 4
D HBO1 complex
D MOZ/MORF complex
D SAGA complex
E MNEG_5586 hypothetical protein K11363 SGF11; SAGA-associated factor 11
E MNEG_1322 Transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E MNEG_0603 hypothetical protein K03134 TAF10; transcription initiation factor TFIID subunit 10
E MNEG_0683 Transcription initiation factor TFIID subunit12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E MNEG_12320 hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E MNEG_8591 Enhancer of yellow 2 transcription factor-like protein K11368 ENY2; enhancer of yellow 2 transcription factor
D SLIK complex
E MNEG_5586 hypothetical protein K11363 SGF11; SAGA-associated factor 11
E MNEG_1322 Transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E MNEG_0603 hypothetical protein K03134 TAF10; transcription initiation factor TFIID subunit 10
E MNEG_0683 Transcription initiation factor TFIID subunit12 K03126 TAF12; transcription initiation factor TFIID subunit 12
E MNEG_12320 hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D ADA-HAT complex
D HAT-A2 complex
D ATAC complex
E MNEG_2855 hypothetical protein K21751 DR1; down-regulator of transcription 1
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
D HATB complex
E MNEG_5207 Histone acetyltransferase type B catalytic subunit K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D NSL complex
E MNEG_0786 histone acetyltransferase MYST1 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
E MNEG_0970 putative UDP-N-acetylglucosamine--peptideN- acetylglucosaminyltransferase SPINDLY K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
D MSL complex
E MNEG_0786 histone acetyltransferase MYST1 K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D NuA3 complex
D NuA4 complex
E MNEG_3085 putative Protein AF-9 like protein K11341 YEATS4; YEATS domain-containing protein 4
E MNEG_0450 DNA methyltransferase 1-associated protein K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
D Class II HDACs
E MNEG_10960 histone deacetylase 6/10 K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
E MNEG_2330 NAD-dependent deacetylase sirtuin 2 K11412 SIRT2; NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
E MNEG_2628 NAD-dependent deacetylase sirtuin 2 K11412 SIRT2; NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
E MNEG_1281 histone deacetylase K11414 SIRT4; NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313]
E MNEG_13406 putative sirtuin (silent mating type information regulation 2 like protein) 5 K11415 SIRT5; NAD-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
E MNEG_8254 mono-ADP-ribosyltransferase sirtuin 6 K11416 SIRT6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
D Class IV HDACs
C HDAC complexes
D Sin3A-HDAC complex
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D BRAF-HDAC complex
D REST complex
D SHIP complex
D MiDAC complex
D SMART complex
E MNEG_3992 transducin (beta)-like 1 K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E MNEG_9948 hypothetical protein K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
E MNEG_12904 hypothetical protein K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
D PRMTs (protein arginine metyltransferases)
E MNEG_13529 protein arginine N-methyltransferase 1 K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E MNEG_1726 putative protein arginine N-methyltransferase 4.2 K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E MNEG_13076 histone-arginine methyltransferase CARM1 K05931 CARM1; type I protein arginine methyltransferase [EC:2.1.1.319]
E MNEG_0265 protein arginine N-methyltransferase 5 K02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]
E MNEG_10514 putative Protein arginine N-methyltransferase 5 K02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]
E MNEG_11764 hypothetical protein K18477 RMT2; type IV protein arginine methyltransferase [EC:2.1.1.322]
C HMT complexes
D COMPASS/SET1 complex
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
E MNEG_0868 Set1/Ash2 histone methyltransferase complex subunit ASH2 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
D COMPASS/SET1 complex (yeast)
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
D MLL-HCF complex
E MNEG_0868 Set1/Ash2 histone methyltransferase complex subunit ASH2 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
D MLL3/MLL4 complex
E MNEG_0868 Set1/Ash2 histone methyltransferase complex subunit ASH2 K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
E MNEG_1338 hypothetical protein K14972 PAXIP1; PAX-interacting protein 1
D Dot1-containing complex
C Histone demethylases
D MNEG_3041 hypothetical protein K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
D MNEG_6536 jumonji domain containing 5 K24444 JMJ30; [histone H3]-dimethyl/trimethyl-L-lysine36 demethylase [EC:1.14.11.27 1.14.11.-]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E MNEG_11188 hypothetical protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E PRC1.4 specific proteins
D Noncanonical PRC1 (PRC1.1)
E MNEG_11188 hypothetical protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E MNEG_0264 SKP1-like protein 1A K03094 SKP1; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E MNEG_11188 hypothetical protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E MNEG_3515 Casein kinase II subunit beta K03115 CSNK2B; casein kinase II subunit beta
D Noncanonical PRC1 (PRC1.6)
E MNEG_11188 hypothetical protein K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E MNEG_12802 Transcription factor Dp-1 K04683 TFDP1; transcription factor Dp-1
E MNEG_10359 Protein Mut11 K14963 WDR5; COMPASS component SWD3
D PRC2.1
E MNEG_3702 Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM K11462 EED; polycomb protein EED
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D PRC2.2
E MNEG_3702 Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM K11462 EED; polycomb protein EED
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D PR-DUB complex
E MNEG_0970 putative UDP-N-acetylglucosamine--peptideN- acetylglucosaminyltransferase SPINDLY K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
D Other PRC associated proteins
E MNEG_11748 hypothetical protein K26267 SAP30BP; SAP30-binding protein
C Sir proteins
C Other histone modification proteins
D MNEG_0353 hypothetical protein K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D MNEG_9656 Squamous cell carcinoma antigen recognized by T-cell 3 K22611 SART3; squamous cell carcinoma antigen recognized by T-cells 3
D MNEG_13719 putative Gastrulation defective protein 1 like protein K24752 WDR70; WD repeat-containing protein 70
D MNEG_13172 hypothetical protein K26537 UXT; protein UXT
B Chromosome condensation proteins
C Condensin I
D MNEG_13637 chromosome condensation complex condensin, subunit H K06676 BRRN1; condensin complex subunit 2
D MNEG_7715 hypothetical protein K06678 YCG1; condensin complex subunit 3
C Condensin II
D MNEG_2384 hypothetical protein K11490 NCAPH2; condensin-2 complex subunit H2
D MNEG_6562 Condensin-2 complex subunit D3 K11491 NCAPD3; condensin-2 complex subunit D3
C Other regulators of chromosome condensation
D MNEG_10931 hypothetical protein K11493 RCC1; regulator of chromosome condensation
D MNEG_3466 hypothetical protein K11493 RCC1; regulator of chromosome condensation
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
E MNEG_0339 centromeric protein E K11498 CENPE; centromeric protein E
D CPC (chromosomal passenger complex)
D KMN network proteins
E MIS12 complex
E NDC80 complex
F MNEG_4835 putative Kinetochore protein NDC80 K11547 NDC80; kinetochore protein NDC80
F MNEG_10538 Kinetochore protein nuf2 K11548 NUF2; kinetochore protein Nuf2
F MNEG_1947 hypothetical protein K11550 SPBC25; kinetochore protein Spc25, animal type
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
F MNEG_4835 putative Kinetochore protein NDC80 K11547 NDC80; kinetochore protein NDC80
F MNEG_10538 Kinetochore protein nuf2 K11548 NUF2; kinetochore protein Nuf2
E MIND kinetochore complex
D MIS16-MIS18 complex
E MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D DASH complex
D CBF3 complex
E MNEG_0264 SKP1-like protein 1A K03094 SKP1; S-phase kinase-associated protein 1
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
E MNEG_10807 hypothetical protein K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
E MNEG_9980 Mitotic spindle assembly checkpoint protein MAD2A K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
E MNEG_7738 Mitotic spindle assembly checkpoint protein MAD2B K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
E MNEG_13564 Mitotic checkpoint protein BUB3 K02180 BUB3; cell cycle arrest protein BUB3
D Motor proteins
E MNEG_0339 centromeric protein E K11498 CENPE; centromeric protein E
E RZZ complex
E Dynein complex
E MNEG_2837 kinesin-13 K10393 KIF2_24; kinesin family member 2/24
E MNEG_2303 kinesin family member 2/24 K10393 KIF2_24; kinesin family member 2/24
D Protein kinases
E MNEG_9788 serine/threonine-protein kinase TTK/MPS1 K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
E MNEG_5225 MAP kinase K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
D Others
E MNEG_6502 chromatin remodeling complex subunit K20093 ERCC6L; DNA excision repair protein ERCC-6-like [EC:5.6.2.-]
E MNEG_11567 hypothetical protein K22399 TRIP13; pachytene checkpoint protein 2
E MNEG_6132 hypothetical protein K26094 SKA1; spindle and kinetochore-associated protein 1
E MNEG_8269 hypothetical protein K26095 SKA2; spindle and kinetochore-associated protein 2
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
E MNEG_14279 protein phosphatase 2 (formerly 2A),catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E MNEG_3310 protein phosphatase 2 (formerly 2A), catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E MNEG_11012 Serine/threonine-protein phosphatase 2A regulatory subunit A beta isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E MNEG_6780 Protein phosphatase PP2A regulatory subunit B K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E MNEG_4582 Serine/threonine protein phosphatase 2A K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E MNEG_13968 Serine/threonine-protein phosphatase 2Aregulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E MNEG_12306 Serine/threonine protein phosphatase 2A regulatory subunit B' beta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E MNEG_4206 Serine/threonine protein phosphatase 2A K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
C MBPs (metylated DNA binding proteins)
D MNEG_6094 methyl-CpG binding domain protein 4 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
C Other heterochromatin formation proteins
D MNEG_7465 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
D MNEG_7541 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
D MNEG_6085 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B Gene silencing
C RISC (RNA-induced silencing complex)
D MNEG_10630 Protein argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
D MNEG_11031 ATP-dependent RNA helicase K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
C piRNA pathway
D MNEG_10272 ATP-dependent RNA helicase DDX6/DHH1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D MNEG_5930 ATP-dependent RNA helicase DDX6/DHH1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D MNEG_0227 hypothetical protein K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
E MNEG_10630 Protein argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
D RDRC (RNA-directed RNA polymerase complex)
E MNEG_1492 RNA-dependent RNA polymerase 1 K11699 RDR; RNA-dependent RNA polymerase [EC:2.7.7.48]
D Other RNAi proteins
C microRNA pathway
D Microprocessor complex
D RISC loading complex
E MNEG_10630 Protein argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
D Other miRNA pathway proteins
E MNEG_0492 hypothetical protein K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
C Transposable elements
B Centrosome formation proteins
C Centriole proteins
D MNEG_4840 Nephrocystin-3 K16458 CEP104; centrosomal protein CEP104
D MNEG_0417 hypothetical protein K16466 CETN3; centrin-3
D MNEG_10302 Leucine-rich repeat and coiled-coildomain-containing protein 1 K16475 LRRCC1; leucine-rich repeat and coiled-coil domain-containing protein 1
D MNEG_3971 putative Spindle assembly abnormal protein 6 like protein K16487 SAS-6; spindle assembly abnormal protein 6
D MNEG_0788 spindle pole body protein K16489 SFI1; protein SFI1
C Pericentriolar materials (PCM)
D Centriolar satellite
E MNEG_11706 putative Bardet-Biedl syndrome 4 protein like protein K16531 BBS4; Bardet-Biedl syndrome 4 protein
E MNEG_0942 hypothetical protein K16535 FOPNL; lisH domain-containing protein FOPNL
D Other PCM proteins
E MNEG_2756 hypothetical protein K16547 NEDD1; protein NEDD1
C Cyclins
D MNEG_12228 Cyclin-A2-1 K06627 CCNA; cyclin-A
D MNEG_1241 Cyclin-A3-2 K06627 CCNA; cyclin-A
D MNEG_10867 G2/mitotic-specific cyclin-A K06627 CCNA; cyclin-A
D MNEG_1002 Cyclin-A1-1 K06627 CCNA; cyclin-A
D MNEG_1672 Cyclin-B1-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D MNEG_6957 Cyclin-B1-4 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D MNEG_6826 Cyclin-B2-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D MNEG_2224 Cyclin-B2-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D MNEG_7494 Cyclin-B1-4 K21777 CCNB; G2/mitotic-specific cyclin-B, other
C Kinases and associated factors
D MNEG_15636 hypothetical protein K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
D MNEG_7075 protein kinase, cGMP-dependent K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E MNEG_13547 Tubulin gamma chain K10389 TUBG; tubulin gamma
E MNEG_4943 Gamma-tubulin complex component 2 K16569 TUBGCP2; gamma-tubulin complex component 2
E MNEG_4000 putative Gamma-tubulin complex component 3 like protein K16570 TUBGCP3; gamma-tubulin complex component 3
E MNEG_2756 hypothetical protein K16547 NEDD1; protein NEDD1
D Other tubulins
E MNEG_6556 Tubulin alpha-1 chain K07374 TUBA; tubulin alpha
E MNEG_4560 Tubulin alpha chain K07374 TUBA; tubulin alpha
E MNEG_16252 Tubulin alpha chain K07374 TUBA; tubulin alpha
E MNEG_2852 Tubulin beta chain K07375 TUBB; tubulin beta
E MNEG_5430 Tubulin beta chain K07375 TUBB; tubulin beta
E MNEG_4088 Tubulin delta chain K10390 TUBD; tubulin delta
E MNEG_5289 Tubulin epsilon chain K10391 TUBE; tubulin epsilon
D Dynactin complex
D BRISC complex
D Microtubule-associated proteins
E MNEG_9452 Microtubule-associated protein RP/EB family member 1 K10436 MAPRE; microtubule-associated protein, RP/EB family
E MNEG_1043 hypothetical protein K19573 ATAT1; alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108]
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
E MNEG_12717 hypothetical protein K02183 CALM; calmodulin
E MNEG_5147 calmodulin K02183 CALM; calmodulin
E MNEG_4087 hypothetical protein K02183 CALM; calmodulin
E MNEG_14446 hypothetical protein K02183 CALM; calmodulin
E MNEG_4387 hypothetical protein K02183 CALM; calmodulin
E MNEG_1189 Dynein light chain, flagellar outer arm K02183 CALM; calmodulin
E MNEG_1146 hypothetical protein K02183 CALM; calmodulin
E MNEG_8507 Calmodulin K02183 CALM; calmodulin
E MNEG_3971 putative Spindle assembly abnormal protein 6 like protein K16487 SAS-6; spindle assembly abnormal protein 6
D Regulators of centriole replication
E MNEG_10457 hypothetical protein K19788 OLA1; obg-like ATPase 1
E MNEG_9374 GTP-dependent nucleic acid-binding protein D K19788 OLA1; obg-like ATPase 1
E MNEG_12473 GTP-binding nuclear protein Ran-2 K07936 RAN; GTP-binding nuclear protein Ran
E MNEG_8066 GTP-binding nuclear protein Ran-A1 K07936 RAN; GTP-binding nuclear protein Ran
D Other centrosome duplication proteins
E MNEG_12354 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
E MNEG_0822 leishmanolysin-like peptidase K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E MNEG_11972 Origin recognition complex subunit 1 K02603 ORC1; origin recognition complex subunit 1
E MNEG_1081 Origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
E MNEG_0212 hypothetical protein K16732 PRC1; Ase1/PRC1/MAP65 family protein
E MNEG_11355 hypothetical protein K27678 ENKD1; enkurin domain-containing protein 1
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Other centriole associated proteins
D MNEG_4011 fructose-bisphosphate aldolase, class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D MNEG_3931 fructose-bisphosphate aldolase, class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D MNEG_1394 fructose-bisphosphate aldolase, class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D MNEG_14924 fructose-bisphosphate aldolase, class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D MNEG_7354 fructose-bisphosphate aldolase, class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D MNEG_11460 ADP-ribosylation factor-like protein 2 K07943 ARL2; ADP-ribosylation factor-like protein 2
D MNEG_11242 putative Abnormal spindle-like microcephaly-associated protein like protein K16743 ASPM; abnormal spindle-like microcephaly-associated protein
D MNEG_6320 hypothetical protein K16743 ASPM; abnormal spindle-like microcephaly-associated protein
D MNEG_4089 Coiled-coil domain-containing protein 61 K16755 CCDC61; coiled-coil domain-containing protein 61
D MNEG_1000 Coiled-coil domain-containing protein 77 K16757 CCDC77; coiled-coil domain-containing protein 77
D MNEG_5939 Exocyst complex component 7 K07195 EXOC7; exocyst complex component 7
D MNEG_2989 small rab-related GTPase K07901 RAB8A; Ras-related protein Rab-8A
D MNEG_0119 deflagellation-inducible protein K16780 SSNA1; sjoegren syndrome nuclear autoantigen 1
D MNEG_15600 vacuolar protein-sorting-associated protein 4 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D MNEG_13989 Protein SAP1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D MNEG_6627 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D MNEG_7627 Uncharacterized protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D MNEG_7711 putative Exportin-2 K18423 CSE1; exportin-2 (importin alpha re-exporter)
D MNEG_2837 kinesin-13 K10393 KIF2_24; kinesin family member 2/24
D MNEG_2303 kinesin family member 2/24 K10393 KIF2_24; kinesin family member 2/24
D MNEG_6526 Kinesin-like protein KIP1 K10398 KIF11; kinesin family member 11
D MNEG_9177 Kinesin-1 K10405 KIFC1; kinesin family member C1
D MNEG_2162 Kinesin-2 K10405 KIFC1; kinesin family member C1
D MNEG_5860 Kinesin-1 K10405 KIFC1; kinesin family member C1
D MNEG_1007 Kinesin-2 K10405 KIFC1; kinesin family member C1
D MNEG_10273 Importin subunit alpha-1 K15042 KPNA5_6; importin subunit alpha-6/7
D MNEG_8045 Importin subunit beta-1 K14293 KPNB1; importin subunit beta-1
D MNEG_4229 Importin subunit beta-1 K14293 KPNB1; importin subunit beta-1
D MNEG_3764 hypothetical protein K14304 NUP85; nuclear pore complex protein Nup85
D MNEG_9488 hypothetical protein K14304 NUP85; nuclear pore complex protein Nup85
D MNEG_2405 Nuclear pore complex protein Nup98 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
D MNEG_8583 hypothetical protein K20724 TMEM33; transmembrane protein 33
D MNEG_13671 Rae1-like protein K14298 RAE1; mRNA export factor
D MNEG_12473 GTP-binding nuclear protein Ran-2 K07936 RAN; GTP-binding nuclear protein Ran
D MNEG_8066 GTP-binding nuclear protein Ran-A1 K07936 RAN; GTP-binding nuclear protein Ran
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
C APC/C complex
D MNEG_12229 anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D MNEG_11979 hypothetical protein K03352 APC5; anaphase-promoting complex subunit 5
D MNEG_11779 putative Cell division cycle protein 16 K03353 APC6; anaphase-promoting complex subunit 6
D MNEG_0352 anaphase-promoting complex subunit 8 K03355 APC8; anaphase-promoting complex subunit 8
D MNEG_5004 hypothetical protein K12456 APC13; anaphase-promoting complex subunit 13
D MNEG_2026 putative Cell division cycle protein 20 K03363 CDC20; cell division cycle 20, cofactor of APC complex
C Aurora kinases
D MNEG_3233 aurora kinase A K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D Regulators of Aurora kinases
E MNEG_7800 hypothetical protein K16833 PPP1R2; protein phosphatase inhibitor 2
C TACC proteins
C Polo kinases
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
D MNEG_0072 SWI/SNF complex subunit SWI3D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D MNEG_5990 putative SWI/SNF complex component SNF12 like protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C PBAF complex
D MNEG_0072 SWI/SNF complex subunit SWI3D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D MNEG_5990 putative SWI/SNF complex component SNF12 like protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C GBAF(ncBAF) complex
D MNEG_0072 SWI/SNF complex subunit SWI3D K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D MNEG_5990 putative SWI/SNF complex component SNF12 like protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C CHRAC complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D MNEG_11435 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C RSF complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C WICH complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C B-WICH complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D MNEG_1072 cystathionine gamma-synthase K16911 DDX21; ATP-dependent RNA helicase DDX21 [EC:5.6.2.7]
D MNEG_10890 Protein DEK K17046 DEK; protein DEK
C NORC complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C BRF complex
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C NuRD complex
D MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex
D MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex (fruit fly)
D MNEG_8670 SWI/SNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D MNEG_6548 WD-40 repeat-containing protein MSI1 K10752 RBBP4; histone-binding protein RBBP4
C CERF complex
C SRCAP complex
D MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D MNEG_0450 DNA methyltransferase 1-associated protein K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D MNEG_3085 putative Protein AF-9 like protein K11341 YEATS4; YEATS domain-containing protein 4
D MNEG_5781 zinc finger HIT domain-containing protein 1 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
C INO80 complex
D MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D MNEG_4426 Actin-related protein 5 K11672 ACTR5; actin-related protein 5
C INO80 complex (yeast)
D MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D MNEG_4426 Actin-related protein 5 K11672 ACTR5; actin-related protein 5
C RSC complex
C SWI/SNF complex
C SWR1 complex
D MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D MNEG_3085 putative Protein AF-9 like protein K11341 YEATS4; YEATS domain-containing protein 4
D MNEG_5781 zinc finger HIT domain-containing protein 1 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D MNEG_0450 DNA methyltransferase 1-associated protein K11324 DMAP1; DNA methyltransferase 1-associated protein 1
C ASTRA complex
D MNEG_11424 RuvB-like protein 1 (pontin 52) K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D MNEG_4791 RuvB-like protein 2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D MNEG_6569 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
C Other chromatin remodeling factors
D MNEG_5987 hypothetical protein K14440 SMARCAL1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-]
D MNEG_12793 helicase, lymphoid-specific K19001 HELLS; ATP-dependent DNA helicase
D MNEG_14938 hypothetical protein K23408 CDCA7; cell division cycle-associated protein 7
D MNEG_10793 hypothetical protein K23408 CDCA7; cell division cycle-associated protein 7
D MNEG_4054 putative Protein strawberry notch K26273 SBNO; protein strawberry notch
D MNEG_12848 putative Protein strawberry notch K26273 SBNO; protein strawberry notch
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AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
C HU (heat unstable protein)
C IHF (integration host factor)
C Other nucleoid associated proteins
B Chromosome partitioning proteins
C MukBEF complex
C Condensin-like complex
C Divisome proteins
D MNEG_2985 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D MNEG_9144 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D MNEG_8484 hypothetical protein K03531 ftsZ; cell division protein FtsZ
C Inhibitors of FtsZ assembly
C Other chromosome partitioning proteins
D MNEG_9127 tRNA uridine 5-carboxymethylaminomethylmodification enzyme mnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D MNEG_2235 glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D MNEG_10175 Nucleotide-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D MNEG_9159 GTP-binding protein K03978 engB; GTP-binding protein
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 12, 2024