+F Repair protein KO #

  DNA Repair and Recombination Proteins - Monoraphidium neglectum

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D MNEG_7529 methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D MNEG_13885 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E MNEG_14787 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MNEG_6754 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MNEG_6094 methyl-CpG binding domain protein 4 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] E MNEG_8709 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] E MNEG_5657 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex F MNEG_1145 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F MNEG_9271 DNA polymerase delta subunit 1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F MNEG_1736 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4 E DNA polymerase epsilon complex F MNEG_12697 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] F MNEG_11435 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] E MNEG_1959 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E MNEG_8774 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen D Short Patch-BER factors D Other BER factors E MNEG_4264 Transcription factor bHLH140 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E MNEG_4476 bifunctional polynucleotidephosphatase/kinase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] E MNEG_0586 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex F MNEG_4176 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F MNEG_4938 cullin 4 K10609 CUL4; cullin 4 F MNEG_2408 DNA damage-binding protein 1a K10610 DDB1; DNA damage-binding protein 1 F MNEG_10255 Protein DAMAGED DNA-BINDING 2 K10140 DDB2; DNA damage-binding protein 2 E NER4 complex F MNEG_13186 hypothetical protein K15083 RAD16; DNA repair protein RAD16 D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex F MNEG_12639 DNA-directed RNA polymerase II subunit RPB3-A K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 F MNEG_9076 DNA-directed RNA polymerase II subunit E K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 F MNEG_9762 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 F MNEG_5322 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 F MNEG_7835 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 F MNEG_12379 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F MNEG_0306 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 F MNEG_2353 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 F MNEG_2692 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 E Cul4-CSA complex F MNEG_4176 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F MNEG_4938 cullin 4 K10609 CUL4; cullin 4 F MNEG_2408 DNA damage-binding protein 1a K10610 DDB1; DNA damage-binding protein 1 E Other TCR factor F MNEG_8542 Transcription elongation factor 1 K25829 ELOF1; transcription elongation factor 1 D TFIIH complex E MNEG_0064 DNA excision repair protein ERCC-2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] E MNEG_1330 RNA polymerase II transcription factor B subunit 2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 E MNEG_8149 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit E MNEG_5429 Cyclin-H1-1 K06634 CCNH; cyclin H D RPA (replication factor A) E MNEG_0168 Replication protein A DNA-binding subunit K07466 RFA1; replication factor A1 E MNEG_1371 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_8716 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_5011 hypothetical protein K10740 RPA3; replication factor A3 D Other NER factors E MNEG_3211 putative DNA repair endonuclease UVH1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] E MNEG_8650 putative MMS19 nucleotide excision repair protein K15075 MET18; DNA repair/transcription protein MET18/MMS19 E MNEG_7296 cullin 3 K03869 CUL3; cullin 3 C MMR (mismatch excision repair) D Mismatch and loop recognition factors E MNEG_9220 DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2 E MNEG_16523 DNA mismatch repair protein MSH2 K08735 MSH2; DNA mismatch repair protein MSH2 E MNEG_14639 DNA mismatch repair protein Msh3 K08736 MSH3; DNA mismatch repair protein MSH3 E MNEG_2780 putative DNA mismatch repair protein Msh6-2 K08737 MSH6; DNA mismatch repair protein MSH6 D MutL homologs E MNEG_0185 putative MutL protein K08734 MLH1; DNA mismatch repair protein MLH1 D DNA polymerase delta complex E MNEG_1145 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E MNEG_9271 DNA polymerase delta subunit 1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E MNEG_1736 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4 D RPA (replication factor A) E MNEG_0168 Replication protein A DNA-binding subunit K07466 RFA1; replication factor A1 E MNEG_1371 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_8716 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_5011 hypothetical protein K10740 RPA3; replication factor A3 D RFC (replication factor C) E MNEG_8127 replication factor C subunit 2/4 K10755 RFC2_4; replication factor C subunit 2/4 E MNEG_5877 Replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 E MNEG_4777 Replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 D Other MMR factors E MNEG_1959 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E MNEG_8774 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E MNEG_7240 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-] E MNEG_6085 hypothetical protein K24755 WDR76; WD repeat-containing protein 76 B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex E MNEG_3590 Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] D BRCA1-C complex D BRCA complex E MNEG_12354 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein E MNEG_7488 putative DNA repair protein RAD51 like protein K04482 RAD51; DNA repair protein RAD51 D RecA family proteins E MNEG_7488 putative DNA repair protein RAD51 like protein K04482 RAD51; DNA repair protein RAD51 E MNEG_5735 RAD51-like protein 2 K10870 RAD51L2; RAD51-like protein 2 D Rad52 family proteins D Rad54 family proteins E MNEG_6158 DNA repair and recombination protein RAD54 and RAD54-like protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E MNEG_10899 DNA repair and recombination protein RAD54 and RAD54-like protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E MNEG_5964 DNA repair and recombination protein RAD54B K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] D RecQ family DNA helicases E MNEG_4232 ATP-dependent DNA helicase Q1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] D Bloom's syndrome complex (BTR) E MNEG_8196 topoisomerase (DNA) III beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D RPA (replication factor A) E MNEG_0168 Replication protein A DNA-binding subunit K07466 RFA1; replication factor A1 E MNEG_1371 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_8716 replication factor A2 K10739 RFA2; replication factor A2 E MNEG_5011 hypothetical protein K10740 RPA3; replication factor A3 D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex E MNEG_1167 Structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5 E MNEG_6995 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] E MNEG_7048 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4 E MNEG_2576 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4 D Other HR factors E MNEG_1343 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1 E MNEG_9874 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1 E MNEG_0484 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] E MNEG_2668 putative Flap endonuclease GEN K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] E MNEG_10779 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E MNEG_8152 SAM domain and HD domain-containing protein 1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E MNEG_15600 vacuolar protein-sorting-associated protein 4 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] E MNEG_13989 Protein SAP1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] E MNEG_6627 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] E MNEG_10765 DNA damage response protein WSS1 K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-] C NHEJ (non-homologous end-joining) D DNA-PK complex E MNEG_6042 ATP-dependent DNA helicase 2 subunit 2 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases E MNEG_0586 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] D Other NHEJ factors E MNEG_4264 Transcription factor bHLH140 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E MNEG_7541 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 C FA (Fanconi anemia) pathway D FA core complex E MNEG_3668 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] D FA core complex binding factors E MNEG_6595 ubiquitin-conjugating enzyme E2T (putative) K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] D Bloom's syndrome complex (BTR) E MNEG_8196 topoisomerase (DNA) III beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D FANCD2-I complex E MNEG_4586 Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein D Downstream FA components E MNEG_12354 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein E MNEG_3590 Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] D Other FA pathway factors E MNEG_7488 putative DNA repair protein RAD51 like protein K04482 RAD51; DNA repair protein RAD51 E MNEG_5735 RAD51-like protein 2 K10870 RAD51L2; RAD51-like protein 2 E MNEG_1572 hypothetical protein K15361 WDR48; WD repeat-containing protein 48 C Other DSBR factors D Protein phosphatase 6 E MNEG_7676 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] D Ubiquitin ligases D Others E MNEG_13719 putative Gastrulation defective protein 1 like protein K24752 WDR70; WD repeat-containing protein 70 E MNEG_6085 hypothetical protein K24755 WDR76; WD repeat-containing protein 76 B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D MNEG_12147 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7] D MNEG_6991 DNA polymerase iota subunit K03510 POLI; DNA polymerase iota [EC:2.7.7.7] D MNEG_15180 DNA polymerase kappa subunit K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] D MNEG_14421 DNA repair protein REV1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group D MNEG_0735 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D MNEG_13079 ubc1, ubiquitin carrier protein 1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D MNEG_13566 Ubiquitin-conjugating enzyme E2 variant 1C K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D MNEG_0004 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] C Other TLS factors D MNEG_1959 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen D MNEG_8774 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen B Check point factors C Rad9-Hus1-Rad1 complex D MNEG_11743 HUS1 checkpoint protein K10903 HUS1; HUS1 checkpoint protein D MNEG_14307 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C HRAD17(Rad24)-RFC complex D MNEG_8127 replication factor C subunit 2/4 K10755 RFC2_4; replication factor C subunit 2/4 D MNEG_5877 Replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 D MNEG_4777 Replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 C Rad17-Mec3-Ddc1 complex D MNEG_14307 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C FPC (fork protection complex) C Triple T complex D MNEG_6569 hypothetical protein K20403 TTI1; TELO2-interacting protein 1 C BAG6-UBL4A-GET4 complex D MNEG_1190 hypothetical protein K23387 GET4; golgi to ER traffic protein 4 C Other check point factors D MNEG_6430 ataxia telangectasia mutated family protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] D MNEG_5014 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon D MNEG_7500 14-3-3-like protein K06630 YWHAE; 14-3-3 protein epsilon D MNEG_5754 hypothetical protein K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D MNEG_0630 NIMA (never in mitosis a)-related kinase K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D MNEG_3316 hypothetical protein K22422 DONSON; protein downstream neighbor of Son D MNEG_10178 Vacuolar protein sorting-associating protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4 D MNEG_6622 vacuolar protein-sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4 B Other factors with a suspected DNA repair function C DNA polymerases D MNEG_3356 DNA polymerase theta subunit K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] D MNEG_4911 Coiled-coil domain-containing protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] C Nucleases D MNEG_0034 DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein D MNEG_7992 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-] C Helicases D MNEG_0466 Putative DNA repair and recombination protein RAD26-like protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] C PSO4 complex D MNEG_6235 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] D MNEG_0137 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27 D MNEG_12233 PP1/PP2A phosphatases pleiotropic regulator PRL1 K12862 PLRG1; pleiotropic regulator 1 C Modulation of nucleotide pools D MNEG_1641 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MNEG_14463 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MNEG_13580 ribonucleoside-diphosphate reductase largesubunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] D MNEG_1584 ribonucleoside-diphosphate reductasesubunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D MNEG_1585 ribonucleoside-diphosphate reductasesubunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D MNEG_10972 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D MNEG_10933 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D MNEG_7529 methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D MNEG_13885 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E MNEG_14787 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MNEG_0581 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E MNEG_6754 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MNEG_9036 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E MNEG_5657 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D RecJ D DNA ligase D DNA polymerase I C NER (nucleotide excision repair) D GGR (global genome repair) factors D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) E TRCF (transcription-repair coupling factor) C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme D DNA ligase D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins D RecFOR pathway proteins D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F MNEG_5564 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] E Supressor D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway E Facilitator E Supressor B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases C Modulation of nucleotide pools D MNEG_1641 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MNEG_14463 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024