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Transfer RNA Biogenesis - Methanosphaerula palustris
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D Mpal_0450 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Mpal_2527 ribonuclease P-related protein K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Mpal_2528 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Mpal_0533 RNAse P, Rpr2/Rpp21 subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D Mpal_1973 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D Mpal_1018 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Mpal_1019 protein of unknown function DUF101 K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D Mpal_1553 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Mpal_2371 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mpal_0945 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Mpal_0152 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Mpal_0690 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Mpal_0695 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Mpal_0288 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Mpal_2116 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
C Other AARSs
D Mpal_1287 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Mpal_1061 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Mpal_1303 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Mpal_2658 tRNA synthetase class II (G H P and S) K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Mpal_1158 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Mpal_2064 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Mpal_2198 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Mpal_0570 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Mpal_0569 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Mpal_2791 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Mpal_0571 Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D Mpal_0158 Protein of unknown function DUF516 K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D Mpal_2762 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D Mpal_2545 N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Mpal_2646 protein of unknown function Met10 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Mpal_2535 tRNA methyltransferase complex GCD14 subunit K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Mpal_2483 protein of unknown function UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Mpal_1584 protein of unknown function UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Mpal_0289 Wyosine base formation domain protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D Mpal_1885 protein of unknown function Met10 K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
C Psudouridine synthases
D Mpal_2714 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Mpal_2750 pseudouridylate synthase TruB domain protein K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Mpal_2096 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D Mpal_0546 THUMP domain protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
C Thiolation factors
D Mpal_1672 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Mpal_1837 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Mpal_1371 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
D Mpal_0952 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
C Elongator related proteins
C Other tRNA modification factors
D Mpal_0134 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Mpal_0151 protein of unknown function DUF549 K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D Mpal_R0046 RNA component of RNaseP K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D Mpal_1973 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Mpal_1199 ribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
C CCA adding factors
D Mpal_0013 tRNA cytidylyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
B tRNA spricing factors
C tRNA splicing endonucleases
D Mpal_0572 tRNA intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
C tRNA splicing ligases
D Mpal_1018 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D Mpal_0012 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Mpal_0690 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Mpal_0945 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D Mpal_2791 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Mpal_0571 Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Mpal_1303 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Mpal_0152 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Mpal_2116 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Mpal_1287 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Mpal_2064 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Mpal_0695 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Mpal_2658 tRNA synthetase class II (G H P and S) K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Mpal_1158 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Mpal_2371 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mpal_0288 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Mpal_0570 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Mpal_0569 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Mpal_2198 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Mpal_0276 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Mpal_0290 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D Mpal_1163 Sep-tRNA K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D Mpal_1209 Sep-tRNA K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
C Trans-editing factors
D Mpal_0158 Protein of unknown function DUF516 K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
D Mpal_0683 methanogenesis marker protein 9 K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
C Methylthiotransferases
C Methyltransferases
D Mpal_0717 Methyltransferase type 12 K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D Mpal_1301 RNA methyltransferase, TrmH family, group 1 K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D Mpal_2483 protein of unknown function UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Mpal_1584 protein of unknown function UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Mpal_0545 protein of unknown function DUF358 K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D Mpal_2321 putative RNA methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Mpal_2011 protein of unknown function DUF127 K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
C Psudouridine synthases
D Mpal_2714 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Mpal_2750 pseudouridylate synthase TruB domain protein K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Mpal_2096 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D Mpal_1670 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Mpal_1672 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Mpal_1837 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Mpal_1371 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D Mpal_0598 metalloendopeptidase, glycoprotease family K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D Mpal_2795 Protein of unknown function DUF509 K09119 cgi121; KEOPS complex subunit Cgi121
D Mpal_2521 conserved hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1
C Other tRNA modification factors
D Mpal_0284 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Mpal_0282 queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Mpal_0283 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Mpal_0098 4Fe-4S ferredoxin iron-sulfur binding domain protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D Mpal_0721 4Fe-4S ferredoxin, iron-sulfur binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D Mpal_1831 tRNA-guanine transglycosylase, various specificities K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Mpal_1938 thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Mpal_1206 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Mpal_0030 domain of unknown function DUF1743 K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D Mpal_0134 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024