+F Repair protein KO
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DNA Repair and Recombination Proteins - Methylibium petroleiphilum
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Mpe_A2142 methylated-DNA--cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mpe_A0704 Deoxyribodipyrimidine photo-lyase type I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Mpe_A3459 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Mpe_A3235 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Mpe_A2297 endonuclease III / DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Mpe_A0909 conserved hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
E Mpe_B0296 helicase-associated endonuclease for fork-structured DNA K10896 FANCM; fanconi anemia group M protein
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Mpe_A0503 putative mutator mutt protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mpe_A2570 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Mpe_B0284 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Mpe_A2142 methylated-DNA--cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mpe_A3753 Transcriptional regulator Ada / DNA-O6-methylguanine--protein-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D Mpe_A0704 Deoxyribodipyrimidine photo-lyase type I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Mpe_A2055 putative alpha-deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D Mpe_A3751 DNA-N1-methyladenine dioxygenase K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E Mpe_A3459 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Mpe_A0303 putative DNA polymerase-related protein, bacteriophage-type K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Mpe_A2455 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Mpe_A3235 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Mpe_A0097 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Mpe_A3233 Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Mpe_A2297 endonuclease III / DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Mpe_A0089 DNA-(apurinic or apyrimidinic site) lyase K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Mpe_A2071 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E Mpe_A2751 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Mpe_A1812 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Mpe_A1148 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Mpe_A3346 UvrA family protein K03701 uvrA; excinuclease ABC subunit A
E Mpe_A0103 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E Mpe_A2287 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E Mpe_A1960 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Mpe_A1142 ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mpe_A1148 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Mpe_A1812 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Mpe_A3451 DNA-directed RNA polymerase K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Mpe_A3450 DNA-directed RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Mpe_A3417 DNA-directed RNA polymerase K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Mpe_A2716 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Mpe_A1569 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Mpe_A2842 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E Mpe_A2031 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E Mpe_A1360 Exodeoxyribonuclease I subunit C K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E Mpe_A2482 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Mpe_A2633 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Mpe_A2252 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Mpe_A0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Mpe_A1941 DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E Mpe_A0216 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Mpe_A1859 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Mpe_A0049 DNA-directed DNA polymerase K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mpe_A2256 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mpe_A3347 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mpe_A2534 DNA-directed DNA polymerase K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Mpe_A1812 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Mpe_A1142 ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mpe_A2341 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
E Mpe_A0111 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Mpe_B0351 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Mpe_A1664 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Mpe_A0075 RecA protein K03553 recA; recombination protein RecA
E Mpe_A3236 holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E Mpe_A0327 putative holliday junction DNA helicase protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Mpe_A0482 putative holliday junction endodeoxyribonuclease protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Mpe_A0133 replication restart DNA helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Mpe_A1527 restart primosome assembly protein PriB K02686 priB; primosomal replication protein N
E Mpe_A1360 Exodeoxyribonuclease I subunit C K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E Mpe_A0075 RecA protein K03553 recA; recombination protein RecA
E Mpe_A3556 DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E Mpe_A3737 putative ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Mpe_B0389 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Mpe_A2751 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Mpe_A0652 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Mpe_A2532 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
E Mpe_A3335 putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E Mpe_A3649 DNA recombination-dependent growth factor K03554 rdgC; recombination associated protein RdgC
E Mpe_B0241 DNA recombination-dependent growth factor K03554 rdgC; recombination associated protein RdgC
E Mpe_A3236 holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E Mpe_A0327 putative holliday junction DNA helicase protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Mpe_A0482 putative holliday junction endodeoxyribonuclease protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E Mpe_A1285 DNA helicase/exodeoxyribonuclease V, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E Mpe_A1284 DNA helicase/exodeoxyribonuclease V, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E Mpe_A1336 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E Mpe_B0011 ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase module K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Mpe_A2238 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Mpe_A0003 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F Mpe_A1956 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Mpe_A2751 exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Mpe_A0652 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Mpe_A2532 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
F Mpe_A1812 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F Mpe_A1882 integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
F Mpe_A2245 putative integration host factor beta-subunit (ihf-beta) protein K05788 ihfB; integration host factor subunit beta
E Supressor
F Mpe_A1360 Exodeoxyribonuclease I subunit C K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F Mpe_A0108 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Mpe_A3346 UvrA family protein K03701 uvrA; excinuclease ABC subunit A
F Mpe_A0103 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F Mpe_A2287 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F Mpe_A3165 putative HNS-like transcription regulator protein K03746 hns; DNA-binding protein H-NS
F Mpe_A1370 nucleoid protein H-NS K03746 hns; DNA-binding protein H-NS
F Mpe_B0416 nucleoid protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Mpe_A1234 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Mpe_B0052 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D Mpe_B0048 SOS response UmuD protein, Serine peptidase, MEROPS family S24 K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D Mpe_A0075 RecA protein K03553 recA; recombination protein RecA
D Mpe_A1866 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Mpe_A3335 putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D Mpe_A1534 SOS cell division inhibitor SulA K14160 imuA; protein ImuA
D Mpe_B0617 conserved hypothetical protein K14160 imuA; protein ImuA
D Mpe_A1533 conserved hypothetical protein K14161 imuB; protein ImuB
D Mpe_B0618 conserved hypothetical protein K14161 imuB; protein ImuB
D Mpe_B0619 error-prone DNA polymerase, DnaE-like protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Mpe_A1532 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Mpe_A2341 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
D Mpe_A0111 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Mpe_B0351 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Mpe_A1664 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Mpe_A0074 putative regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Mpe_A0128 putative ATP-dependent DNA helicase rep protein K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D Mpe_A2005 putative ATP-dependent DNA helicase-related protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Mpe_A1517 helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Mpe_B0326 conserved hypothetical ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Mpe_A0503 putative mutator mutt protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mpe_A2570 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Mpe_B0284 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Mpe_B0385 putative ribonucleotide reductase protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Mpe_A3214 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Mpe_A3213 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024