+C Two-component system KO
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Two-Component System - Mesoterricola sediminis
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C METESE_15720 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C METESE_14070 phoB; DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
C METESE_19130 DNA-binding response regulator K07776 regX3; two-component system, OmpR family, response regulator RegX3
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C METESE_33470 creC; two-component sensor histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C METESE_33460 DNA-binding response regulator K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C METESE_05130 kdpD_1; two-component sensor histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C METESE_05940 hypothetical protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C METESE_06800 kdpD_2; two-component sensor histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C METESE_05120 kdpE_1; DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
C METESE_05950 kdpE_2; DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C METESE_17740 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
C METESE_16210 two-component system sensor histidine kinase DcuS K11614 yufL; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
C METESE_16200 two-component system response regulator DcuR K11615 malR; two-component system, CitB family, response regulator MalR
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C METESE_13460 hypothetical protein K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C METESE_22790 hypothetical protein K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C METESE_05310 sensor histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C METESE_05320 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator
C METESE_10780 yehT; transcriptional regulatory protein YehT K02477 K02477; two-component system, LytTR family, response regulator
C METESE_13450 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator
C METESE_22780 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator
C METESE_23870 hypothetical protein K02477 K02477; two-component system, LytTR family, response regulator
C METESE_27980 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
C METESE_29730 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C METESE_29940 sigma-54-dependent Fis family transcriptional regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
C METESE_13180 hypothetical protein K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
C METESE_23460 dctD; Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C METESE_17940 pilS; PAS domain-containing sensor histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C METESE_38060 pilR_3; type 4 fimbriae expression regulatory protein PilR K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C METESE_33070 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C METESE_00880 hypothetical protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C METESE_04870 cheA-1_1; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C METESE_04960 cheA-1_2; chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C METESE_21870 ATPase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C METESE_00850 cheY_1; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_04850 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_04940 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_21920 cheY_2; chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_22980 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_32510 hypothetical protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_32850 hypothetical protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C METESE_05010 cheB-1; chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C METESE_21900 cheB_1; chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C METESE_27880 cheB_2; chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C METESE_20650 chemotaxis protein CheR K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C METESE_21250 hypothetical protein K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
C METESE_15360 pleD; PleD family two-component system response regulator K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C METESE_16470 fleS; PAS domain-containing sensor histidine kinase K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C METESE_26900 sigma-54-dependent Fis family transcriptional regulator K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C METESE_07160 fused response regulator/phosphatase K20977 hsbR; two-component system, HptB-dependent secretion and biofilm response regulator
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C METESE_15890 hypothetical protein K02486 K02486; two-component system, sensor kinase [EC:2.7.13.3]
C METESE_30750 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C METESE_31320 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023