+F Repair protein KO
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DNA Repair and Recombination Proteins - Methylocaldum szegediense
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E MSZNOR_2457 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MSZNOR_1487 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MSZNOR_4747 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MSZNOR_4252 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MSZNOR_2515 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E MSZNOR_2457 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MSZNOR_1614 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MSZNOR_4182 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MSZNOR_0892 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MSZNOR_1487 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MSZNOR_3197 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MSZNOR_0794 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MSZNOR_4747 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MSZNOR_2205 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E MSZNOR_3814 DNA uridine endonuclease K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E MSZNOR_2997 nfi; Endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
E MSZNOR_1230 conserved protein of unknown function K09120 dU; endonuclease dU
D RecJ
E MSZNOR_2240 recJ; ssDNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MSZNOR_2739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MSZNOR_1325 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MSZNOR_4199 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
E MSZNOR_3516 uvrB; excision nuclease subunit B K03702 uvrB; excinuclease ABC subunit B
E MSZNOR_4454 uvrC; excision nuclease subunit C K03703 uvrC; excinuclease ABC subunit C
E MSZNOR_4227 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MSZNOR_1325 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MSZNOR_2739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MSZNOR_2776 rpoB; RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MSZNOR_2775 rpoC; RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MSZNOR_3591 rpoA; RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MSZNOR_1184 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MSZNOR_5020 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MSZNOR_3627 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E MSZNOR_4964 MutS-like protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E MSZNOR_1914 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MSZNOR_1364 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E MSZNOR_0493 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MSZNOR_4590 xseB; exodeoxyribonuclease VII subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MSZNOR_3869 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MSZNOR_3118 dnaN; beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MSZNOR_0183 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E MSZNOR_4000 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MSZNOR_3766 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MSZNOR_2128 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MSZNOR_5019 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MSZNOR_2739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MSZNOR_4227 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MSZNOR_4197 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MSZNOR_P0034 vsr; XorII very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MSZNOR_2289 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E MSZNOR_4180 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E MSZNOR_2614 recD; RecBCD enzyme subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MSZNOR_3485 recD2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MSZNOR_3630 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E MSZNOR_5027 ruvA; Holliday junction branch migration complex subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MSZNOR_5029 ruvB; Holliday junction branch migration complex subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MSZNOR_5026 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MSZNOR_3286 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MSZNOR_1364 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E MSZNOR_3630 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E MSZNOR_0679 radA; DNA recombination protein K04485 radA; DNA repair protein RadA/Sms
E MSZNOR_3116 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MSZNOR_1181 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MSZNOR_2240 recJ; ssDNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MSZNOR_1135 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MSZNOR_5017 recR; DNA repair protein RecR K06187 recR; recombination protein RecR
E MSZNOR_3555 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MSZNOR_1483 rdgC; Recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E MSZNOR_5027 ruvA; Holliday junction branch migration complex subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MSZNOR_5029 ruvB; Holliday junction branch migration complex subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MSZNOR_5026 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E MSZNOR_1025 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E MSZNOR_2255 cas; multifunctional nuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E MSZNOR_4855 cas1; CRISPR-associated endonuclease Cas1 1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E MSZNOR_3993 yjgR; DUF853 domain-containing protein YjgR K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MSZNOR_3533 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MSZNOR_3115 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MSZNOR_1722 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MSZNOR_2699 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MSZNOR_2240 recJ; ssDNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MSZNOR_1135 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MSZNOR_5017 recR; DNA repair protein RecR K06187 recR; recombination protein RecR
F MSZNOR_2739 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F MSZNOR_2543 Fis family transcriptional regulator, factor for inversion stimulation protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F MSZNOR_4910 ihfA; Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F MSZNOR_3542 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F MSZNOR_1364 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F MSZNOR_1245 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MSZNOR_3486 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MSZNOR_4199 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
F MSZNOR_3516 uvrB; excision nuclease subunit B K03702 uvrB; excinuclease ABC subunit B
F MSZNOR_5021 DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MSZNOR_2402 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MSZNOR_3630 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
D MSZNOR_0051 lexA; DNA-binding transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D MSZNOR_3555 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MSZNOR_1206 protein ImuB K14161 imuB; protein ImuB
D MSZNOR_1205 dnaE; Error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D MSZNOR_4197 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MSZNOR_3631 regulatory protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D MSZNOR_4019 polX; DNA polymerase type-X / 3'-5' exodeoxyribonuclease K02347 polX; DNA polymerase (family X)
C DNA helicases
D MSZNOR_4819 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D MSZNOR_1100 yoaA; putative ATP-dependent 5' to 3' DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MSZNOR_4970 ATP-dependent helicase Lhr and Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D MSZNOR_4252 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MSZNOR_2515 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MSZNOR_1854 nrdA; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MSZNOR_4635 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025