+F Repair protein KO #

  DNA Repair and Recombination Proteins - Mycobacterium tuberculosis Beijing/NITR203

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D J112_07090 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E J112_15935 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E J112_09010 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E J112_19320 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E J112_19745 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E J112_04630 DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D J112_06275 mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D J112_02200 mutator protein mutT3 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D J112_14455 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D J112_07090 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E J112_15935 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E J112_06780 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E J112_07095 ada regulatory protein alkA K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E J112_09010 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E J112_19320 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E J112_06525 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E J112_15655 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E J112_05085 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E J112_13220 DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E J112_17715 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E J112_19745 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E J112_02275 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E J112_03590 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D RecJ D DNA ligase E J112_16140 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E J112_08715 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E J112_08760 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A E J112_08735 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E J112_07645 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C E J112_05120 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_17160 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_17180 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_08715 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E J112_16140 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F J112_03570 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F J112_03575 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F J112_18600 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F J112_07490 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F J112_05500 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E J112_05985 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E J112_05980 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E J112_08300 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E J112_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E J112_12945 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E J112_19590 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E J112_19945 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E J112_11755 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E J112_19995 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E J112_16140 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E J112_05120 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_17160 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_17180 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E J112_00290 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E J112_13290 hypothetical protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E J112_03370 exonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E J112_03375 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] E J112_03365 exonuclease V alpha subunit recD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E J112_14655 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA E J112_13910 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E J112_13905 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E J112_13915 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E J112_07550 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E J112_14655 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA E J112_19300 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E J112_00015 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF E J112_15920 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E J112_12675 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E J112_19965 recR; recombination protein RecR K06187 recR; recombination protein RecR E J112_09050 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E J112_13910 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E J112_13905 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E J112_13915 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E J112_15085 hypothetical protein K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E J112_13460 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E J112_05055 Ku protein K10979 ku; DNA end-binding protein Ku E J112_05060 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F J112_00030 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F J112_00025 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F J112_19600 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F J112_15985 bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F J112_12675 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F J112_19965 recR; recombination protein RecR K06187 recR; recombination protein RecR F J112_16140 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F J112_08760 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A F J112_08735 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D J112_16370 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D J112_08255 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D J112_14655 recA; DNA recombination protein RecA K03553 recA; recombination protein RecA D J112_14570 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D J112_09050 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D J112_18265 hypothetical protein K14161 imuB; protein ImuB D J112_00290 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D J112_13290 hypothetical protein K03111 ssb; single-strand DNA-binding protein D J112_14650 recX; recombination regulator RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D J112_07170 ATP-dependent helicase DING K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D J112_17710 ATP-dependent helicase lhr K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D J112_06275 mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D J112_02200 mutator protein mutT3 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D J112_15980 putative hydrolase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D J112_09070 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D J112_14455 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D J112_16345 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D J112_03055 ribonucleoside-diphosphate reductase large subunit nrdZ K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D J112_16330 nrdF2; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D J112_01265 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D J112_10555 nrdF1; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D J112_15195 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024