+F Repair protein KO
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DNA Repair and Recombination Proteins - Mycobacterium tuberculosis CCDC5180
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CCDC5180_1209 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CCDC5180_2697 ung, uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CCDC5180_1549 3-methyladenine DNA glycosylase mpg K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CCDC5180_3282 adenine glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CCDC5180_3354 ultraviolet N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E CCDC5180_0789 DNA helicase ercc3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CCDC5180_1065 mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_0382 mutator protein mutT3 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_1458 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_2450 deoxyuridine 5-triphosphate nucleotidohydrolase dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CCDC5180_1209 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CCDC5180_2697 ung, uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CCDC5180_1155 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E CCDC5180_1210 bifunctional methylated-DNA--protein-cysteine methyltransferase/O-6-methylguanine-DNA transcription regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CCDC5180_1549 3-methyladenine DNA glycosylase mpg K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CCDC5180_3282 adenine glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E CCDC5180_1111 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E CCDC5180_0863 hypothetical formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CCDC5180_2649 formamidopyrimidine-DNA glycosylase fpg K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E CCDC5180_3006 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E CCDC5180_2245 DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E CCDC5180_3354 ultraviolet N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CCDC5180_0394 exodeoxyribonuclease III protein xthA K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CCDC5180_0613 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E CCDC5180_2733 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CCDC5180_1494 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CCDC5180_1503 excinuclease ABC subunit A uvrA K03701 uvrA; excinuclease ABC subunit A
E CCDC5180_1498 excinuclease ABC subunit B uvrB K03702 uvrB; excinuclease ABC subunit B
E CCDC5180_1308 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E CCDC5180_0866 ATP-dependent helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_2912 ATP-dependent DNA helicase II uvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_2915 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_1494 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CCDC5180_2733 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CCDC5180_0610 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CCDC5180_0611 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CCDC5180_3156 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CCDC5180_1279 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CCDC5180_0935 transcription-repair coupling factor mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E CCDC5180_1015 exodeoxyribonuclease VII (large subunit) xseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CCDC5180_1430 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CCDC5180_0004 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CCDC5180_2201 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CCDC5180_3329 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CCDC5180_3394 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CCDC5180_2000 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CCDC5180_3404 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CCDC5180_2733 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CCDC5180_0866 ATP-dependent helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_2912 ATP-dependent DNA helicase II uvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_2915 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CCDC5180_0051 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CCDC5180_2258 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CCDC5180_0580 exonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E CCDC5180_0581 exonuclease V gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E CCDC5180_0579 exonuclease V alpha subunit recD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CCDC5180_2482 recA protein (recombinase A) K03553 recA; recombination protein RecA
E CCDC5180_2362 Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E CCDC5180_2361 holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CCDC5180_2363 Holliday junction resolvase ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E CCDC5180_1290 primosomal protein N priA (replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E CCDC5180_2482 recA protein (recombinase A) K03553 recA; recombination protein RecA
E CCDC5180_3278 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E CCDC5180_0005 recombination protein F K03629 recF; DNA replication and repair protein RecF
E CCDC5180_2695 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CCDC5180_2156 hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O)
E CCDC5180_3398 recombination protein RecR K06187 recR; recombination protein RecR
E CCDC5180_1556 DNA repair protein recN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N)
E CCDC5180_2362 Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E CCDC5180_2361 holliday junction DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CCDC5180_2363 Holliday junction resolvase ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E CCDC5180_2286 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E CCDC5180_0857 hypothetical protein K10979 ku; DNA end-binding protein Ku
E CCDC5180_0858 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CCDC5180_0008 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CCDC5180_0007 DNA gyrase subunit B gyrB K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CCDC5180_3331 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CCDC5180_2707 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CCDC5180_2156 hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O)
F CCDC5180_3398 recombination protein RecR K06187 recR; recombination protein RecR
F CCDC5180_2733 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F CCDC5180_1503 excinuclease ABC subunit A uvrA K03701 uvrA; excinuclease ABC subunit A
F CCDC5180_1498 excinuclease ABC subunit B uvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CCDC5180_1421 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D CCDC5180_2777 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D CCDC5180_2482 recA protein (recombinase A) K03553 recA; recombination protein RecA
D CCDC5180_2467 repressor lexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D CCDC5180_1556 DNA repair protein recN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N)
D CCDC5180_3092 hypothetical protein K14161 imuB; protein ImuB
D CCDC5180_3072 DNA polymerase subunit III alpha dnaE2 K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D CCDC5180_0051 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CCDC5180_2258 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D CCDC5180_2481 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D CCDC5180_1223 ATP-dependent helicase dinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D CCDC5180_3005 ATP-dependent helicase lhr K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D CCDC5180_1065 mutator protein mutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_0382 mutator protein mutT3 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_1458 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CCDC5180_2706 hydrolase MutT1 K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D CCDC5180_1560 hypothetical protein K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D CCDC5180_2450 deoxyuridine 5-triphosphate nucleotidohydrolase dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CCDC5180_2773 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CCDC5180_0527 ribonucleoside-diphosphate reductase large subunit NrdZ K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CCDC5180_2770 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D CCDC5180_0216 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D CCDC5180_1805 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D CCDC5180_2566 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024