+F Repair protein KO #

  DNA Repair and Recombination Proteins - Mycobacterium tuberculosis H37Rv

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D Rv1316c ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E Rv2976c ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E Rv1688 mpg; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E Rv3589 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Rv3674c nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E Rv0861c ercc3; DNA helicase Ercc3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D Rv1160 mutT2; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rv0413 mutT3; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rv2697c dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D Rv1316c ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E Rv2976c ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E Rv1259 udgB; uracil DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E Rv1317c alkA; bifunctional regulatory protein/DNA repair enzyme AlkA K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E Rv1688 mpg; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E Rv3589 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Rv1210 tagA; DNA-3-methyladenine glycosylase I TagA K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E Rv0944 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Rv2924c fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Rv3297 nei; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E Rv2464c DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E Rv3674c nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E Rv0427c xthA; exodeoxyribonuclease III protein XthA K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E Rv0670 end; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D RecJ D DNA ligase E Rv3014c ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E Rv1629 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E Rv1638 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E Rv1633 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B E Rv1420 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C E Rv0949 uvrD1; ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv3198c uvrD2; ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv3201c ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv1629 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E Rv3014c ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F Rv0667 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F Rv0668 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F Rv3457c rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F Rv1390 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F Rv1020 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E Rv1108c xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E Rv1107c xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E Rv1547 dnaE1; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E Rv0002 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E Rv2413c hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E Rv3644c DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E Rv3711c dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E Rv2191 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E Rv3721c dnaZX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E Rv3014c ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E Rv0949 uvrD1; ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv3198c uvrD2; ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv3201c ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rv0054 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein E Rv2478c hypothetical protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E Rv0630c recB; exonuclease V subunit beta RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E Rv0631c recC; exonuclease V subunit gamma RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] E Rv0629c recD; exonuclease V subunit alpha RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E Rv2737c recA; recombinase A K03553 recA; recombination protein RecA E Rv2593c ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E Rv2592c ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E Rv2594c ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E Rv1402 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E Rv2737c recA; recombinase A K03553 recA; recombination protein RecA E Rv3585 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E Rv0003 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF E Rv2973c recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E Rv2362c recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E Rv3715c recR; recombination protein RecR K06187 recR; recombination protein RecR E Rv1696 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E Rv2593c ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E Rv2592c ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E Rv2594c ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E Rv2817c CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E Rv2510c hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E Rv0937c mku; non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku E Rv0938 ligD; multifunctional non-homologous end joining DNA repair protein/ATP dependent DNA ligase LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F Rv0006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F Rv0005 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F Rv3646c topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F Rv2986c hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F Rv2362c recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F Rv3715c recR; recombination protein RecR K06187 recR; recombination protein RecR F Rv3014c ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F Rv1638 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F Rv1633 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D Rv3056 dinP; DNA polymerase IV 2 K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D Rv1537 dinX; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D Rv2737c recA; recombinase A K03553 recA; recombination protein RecA D Rv2720 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Rv1696 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Rv3394c hypothetical protein K14161 imuB; protein ImuB D Rv3370c dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D Rv0054 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein D Rv2478c hypothetical protein K03111 ssb; single-strand DNA-binding protein D Rv2736c recX; regulatory protein RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D Rv1329c dinG; ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Rv3296 lhr; ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D Rv1160 mutT2; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rv0413 mutT3; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rv2985 mutT1; 8-oxo-dGTP diphosphatase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D Rv1700 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D Rv2697c dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Rv3051c nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Rv0570 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Rv3048c nrdF2; ribonucleoside-diphosphate reductase subunit beta NrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Rv1981c nrdF1; ribonucleoside-diphosphate reductase subunit beta NrdF1 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Rv0233 nrdB; ribonucleoside-diphosphate reductase subunit beta NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D Rv2837c bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024