+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Mycobacterium tuberculosis Haarlem/NITR202

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D I917_11750 chalcone synthase K16167 bpsA; alkylresorcinol/alkylpyrone synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D I917_16705 mbtH protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase D I917_16785 bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase K04787 mbtA; mycobactin salicyl-AMP ligase [EC:6.3.2.-] D I917_16760 polyketide synthase K04790 mbtC; mycobactin polyketide synthetase MbtC D I917_16755 polyketide synthetase MBTD (polyketide synthase) K04791 mbtD; mycobactin polyketide synthetase MbtD D I917_16745 Peptide synthetase MbtE (peptide synthase) K04789 mbtE; mycobactin peptide synthetase MbtE D I917_16750 peptide synthetase mbtE K04789 mbtE; mycobactin peptide synthetase MbtE D I917_16715 peptide synthetase mbtF K04792 mbtF; mycobactin peptide synthetase MbtF D I917_16720 Peptide synthetase MbtF (peptide synthase) K04792 mbtF; mycobactin peptide synthetase MbtF D I917_16725 amino acid adenylation domain-containing protein K04792 mbtF; mycobactin peptide synthetase MbtF D I917_16730 amino acid adenylation domain-containing protein K04792 mbtF; mycobactin peptide synthetase MbtF C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase C Isonitrile lipopeptide synthase D I917_00715 hypothetical protein K28329 mmaB; acyl carrier protein D I917_00710 acyl-CoA synthetase K12422 fadD10; medium/long-chain-fatty-acid---[acyl-carrier-protein] ligase FadD10 [EC:6.2.1.-] D I917_00705 hypothetical protein K26055 scoD; (3R)-3-[(carboxylmethyl)amino]fatty acid synthase [EC:4.3.2.11] # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase B Methylase B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase C I917_16710 lysine-N-oxygenase MBTG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase) K04793 mbtG; mycobactin lysine-N-oxygenase B Glycosyltransferase B Aminotransferase B Others ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2025