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Mitochondrial Biogenesis - Microcaecilia unicolor
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
D 18490108 ND1; NADH dehydrogenase subunit 1 K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
D 18490089 ND2; NADH dehydrogenase subunit 2 K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
D 18490112 ND3; NADH dehydrogenase subunit 3 K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
D 18490113 ND4; NADH dehydrogenase subunit 4 K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
D 18490102 ND4L; NADH dehydrogenase subunit 4L K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
D 18490117 ND5; NADH dehydrogenase subunit 5 K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
D 18490103 ND6; NADH dehydrogenase subunit 6 K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
C Mitochondrial respiratory chain complex III
D 18490105 CYTB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D 18490094 COX1; cytochrome c oxidase subunit I K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D 18490096 COX2; cytochrome c oxidase subunit II K02261 COX2; cytochrome c oxidase subunit 2
D 18490099 COX3; cytochrome c oxidase subunit III K02262 COX3; cytochrome c oxidase subunit 3
C F-type ATPase
D 18490098 ATP8; ATP synthase F0 subunit 8 K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
D 18490111 ATP6; ATP synthase F0 subunit 6 K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D 115480007 POLRMT; DNA-directed RNA polymerase, mitochondrial isoform X1 K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
D 115470152 TFAM; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
D 115465086 TFB1M; dimethyladenosine transferase 1, mitochondrial isoform X1 K15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]
D 115465752 TFB2M; LOW QUALITY PROTEIN: dimethyladenosine transferase 2, mitochondrial K17653 TFB2M; dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-]
C Mitochondrial translation factors
D 115465746 MTIF2; translation initiation factor IF-2, mitochondrial isoform X1 K02519 infB; translation initiation factor IF-2
D 115468541 MTIF3; translation initiation factor IF-3, mitochondrial K02520 infC; translation initiation factor IF-3
D 115466783 TSFM; elongation factor Ts, mitochondrial K02357 tsf; elongation factor Ts
D 115474103 TUFM; elongation factor Tu, mitochondrial isoform X1 K02358 tuf; elongation factor Tu
D 115463079 GFM2; LOW QUALITY PROTEIN: ribosome-releasing factor 2, mitochondrial K02355 fusA; elongation factor G
D 115479138 GFM1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 115469860 MTERF1; LOW QUALITY PROTEIN: transcription termination factor 1, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 115477582 MTERF2; LOW QUALITY PROTEIN: transcription termination factor 2, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 115466046 transcription termination factor 1, mitochondrial-like K15031 MTERF; mitochondrial transcription termination factor family protein
D 115466052 transcription termination factor 1, mitochondrial-like K15031 MTERF; mitochondrial transcription termination factor family protein
D 115478892 MTERF4; transcription termination factor 4, mitochondrial K15031 MTERF; mitochondrial transcription termination factor family protein
D 115479170 MTERF3; transcription termination factor 3, mitochondrial isoform X1 K15031 MTERF; mitochondrial transcription termination factor family protein
D 115461500 GUF1; translation factor GUF1, mitochondrial K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D 115479288 ribonucleases P/MRP protein subunit POP1-like K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 115459936 ribonucleases P/MRP protein subunit POP1-like K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 115470675 POP4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 115480245 POP5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 115471133 RPP30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 115457609 POP7; ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 115460583 RPP25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 115462818 RPP25L; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 115468291 RPP38; LOW QUALITY PROTEIN: ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 115473709 RPP40; ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
D 115464802 uncharacterized protein LOC115464802 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Mitochondrial ribonuclease P
D 115460505 tRNA methyltransferase 10 homolog C-like K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D 115471404 TRMT10C; tRNA methyltransferase 10 homolog C K17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]
D 115463597 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase type-2 isoform X1 K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
D 115477124 PRORP; mitochondrial ribonuclease P catalytic subunit K17655 MRPP3; mitochondrial ribonuclease P protein 3
C Other mitochondrial DNA transcription and translation factors
D 115476332 MSS51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 115473445 TEFM; transcription elongation factor, mitochondrial isoform X1 K17658 TEFM; transcription elongation factor, mitochondrial
D 115475368 PTCD1; pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
D 115462291 LOW QUALITY PROTEIN: pentatricopeptide repeat-containing protein 2, mitochondrial-like K17711 PTCD2; pentatricopeptide repeat domain-containing protein 2
D 115463094 pentatricopeptide repeat-containing protein 2, mitochondrial-like K17711 PTCD2; pentatricopeptide repeat domain-containing protein 2
D 115461336 PTCD3; pentatricopeptide repeat domain-containing protein 3, mitochondrial isoform X1 K17659 PTCD3; pentatricopeptide repeat domain-containing protein 3
D 115465834 DHX30; ATP-dependent RNA helicase DHX30 isoform X1 K13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]
D 115476618 ubiquinol-cytochrome-c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 115464836 AFG1L; AFG1-like ATPase K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D 115478945 ATP23; mitochondrial inner membrane protease ATP23 homolog isoform X1 K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D 115470189 SUPV3L1; ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform X1 K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D 115478152 LACTB2; endoribonuclease LACTB2 K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D 115473805 SLC25A5; ADP/ATP translocase 2 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 115461576 SLC25A4; ADP/ATP translocase 1 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 115461714 SLC25A31; ADP/ATP translocase 4 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 115469445 SLC25A6; ADP/ATP translocase 3 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D 115469310 SLC25A37; mitoferrin-1 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 115470047 SLC25A28; mitoferrin-2 K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D 115460120 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1 K25803 MALSU1; mitochondrial assembly of ribosomal large subunit protein 1
D 115482508 ERAL1; GTPase Era, mitochondrial isoform X1 K03595 era; GTPase
D 115466695 YARS2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 115479655 YARS1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 115475795 LARS1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 115470427 LARS2; LOW QUALITY PROTEIN: probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 115472790 DARS2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 115466550 GARS1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 115475801 RARS1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 115458819 RARS2; probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 115467309 QRSL1; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D 115461657 GATB; glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial isoform X1 K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D 115479863 GATC; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D 115467469 MTPAP; poly(A) RNA polymerase, mitochondrial K18060 MTPAP; poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19]
D 115471633 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
D 115470212 MTG1; mitochondrial ribosome-associated GTPase 1 isoform X1 K19828 MTG1; mitochondrial GTPase 1
D 115463792 NOA1; nitric oxide-associated protein 1 K19832 NOA1; nitric oxide-associated protein 1
D 115471416 NSUN3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 115472850 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
D 115471676 RPUSD3; LOW QUALITY PROTEIN: mitochondrial mRNA pseudouridine synthase RPUSD3 K22537 RPUSD3; mitochondrial RNA pseudouridine synthase RPUSD3 [EC:5.4.99.-]
D 115473871 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 isoform X1 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
D 115482569 RCC1L; RCC1-like G exchanging factor-like protein isoform X1 K23495 RCC1L; RCC1-like G exchanging factor-like protein
D 115472646 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 K23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]
D 115474383 FASTKD2; FAST kinase domain-containing protein 2, mitochondrial isoform X1 K18190 FASTKD2; FAST kinase domain-containing protein 2
D 115480712 C11H12orf65; probable peptide chain release factor C12orf65 homolog, mitochondrial K23498 COXPD7; peptide chain release factor
D 115477206 RMND1; required for meiotic nuclear division protein 1 homolog K23499 RMND1; required for meiotic nuclear division protein 1
D 115461079 GRSF1; G-rich sequence factor 1 K24984 GRSF1; G-rich sequence factor 1
D 115468738 METTL15; probable methyltransferase-like protein 15 K25876 METTL15; 12S rRNA N4-methylcytidine (m4C) methyltransferase [EC:2.1.1.-]
D 115469481 UPF0160 protein MYG1, mitochondrial-like K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
D 115472531 UPF0160 protein MYG1, mitochondrial-like K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
D 115467311 MTRES1; uncharacterized protein C6orf203 homolog K26186 MTRES1; mitochondrial transcription rescue factor 1
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D 115459877 POLG; LOW QUALITY PROTEIN: DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 115473458 POLG2; DNA polymerase subunit gamma-2, mitochondrial isoform X1 K02333 POLG2; DNA polymerase gamma 2
D 115461579 PRIMPOL; LOW QUALITY PROTEIN: DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D 115465631 MGME1; mitochondrial genome maintenance exonuclease 1 K19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]
D 115460053 EXOG; nuclease EXOG, mitochondrial K15050 EXOG; nuclease EXOG, mitochondrial
D 115471098 TWNK; twinkle protein, mitochondrial K17680 PEO1; twinkle protein [EC:5.6.2.3]
D 115471749 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
D 115478315 SSBP1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
D 115456517 ATAD3A; ATPase family AAA domain-containing protein 3A K17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A/B
D 115481324 ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D 115470820 DNAJA2; dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D 115475385 TOMM34; mitochondrial import receptor subunit TOM34 isoform X1 K17766 TOM34; mitochondrial import receptor subunit TOM34
D 115473447 RHOT1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 115475428 heat shock cognate 71 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 115482041 HSPA8; heat shock cognate 71 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 115466274 heat shock 70 kDa protein 1B K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 115482632 AIPL1; aryl-hydrocarbon-interacting protein-like 1 K17767 AIP; AH receptor-interacting protein
D 115456706 AIP; AH receptor-interacting protein K17767 AIP; AH receptor-interacting protein
B Outer membrane
C Transporter outer membrane (TOM) complex
D 115475564 TOMM40; mitochondrial import receptor subunit TOM40 homolog isoform X1 K11518 TOM40; mitochondrial import receptor subunit TOM40
D 115458061 TOMM40L; mitochondrial import receptor subunit TOM40B K11518 TOM40; mitochondrial import receptor subunit TOM40
D 115470683 TOMM70; mitochondrial import receptor subunit TOM70 K17768 TOM70; mitochondrial import receptor subunit TOM70
D 115475069 TOMM22; mitochondrial import receptor subunit TOM22 homolog K17769 TOM22; mitochondrial import receptor subunit TOM22
D 115466675 TOMM20; mitochondrial import receptor subunit TOM20 homolog K17770 TOM20; mitochondrial import receptor subunit TOM20
D 115460119 TOMM7; mitochondrial import receptor subunit TOM7 homolog K17771 TOM7; mitochondrial import receptor subunit TOM7
D 115462458 TOMM5; mitochondrial import receptor subunit TOM5 homolog K17773 TOM5; mitochondrial import receptor subunit TOM5
C TOB/SAM complex
D 115477884 SAMM50; sorting and assembly machinery component 50 homolog isoform X1 K07277 SAM50; outer membrane protein insertion porin family
C Porin
D 115475936 VDAC1; voltage-dependent anion-selective channel protein 1 K05862 VDAC1; voltage-dependent anion channel protein 1
D 115470229 VDAC2; voltage-dependent anion-selective channel protein 2 K15040 VDAC2; voltage-dependent anion channel protein 2
D 115469432 VDAC3; voltage-dependent anion-selective channel protein 3 K15041 VDAC3; voltage-dependent anion channel protein 3
C ERMES complex
C Other outer membrane factor
D 115473989 MTX2; metaxin-2 K17776 MTX; metaxin
D 115463041 MTX3; metaxin-3 isoform X1 K17776 MTX; metaxin
D 115458294 MTX1; metaxin-1 isoform X1 K17776 MTX; metaxin
D 115456721 MYO19; unconventional myosin-XIX K25838 MYO19; myosin XIX
D 115465496 MARC2; mitochondrial amidoxime reducing component 2 K27318 MTARC; mitochondrial amidoxime-reducing component [EC:1.7.-.-]
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D 115478144 TIMM9; mitochondrial import inner membrane translocase subunit Tim9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D 115460577 mitochondrial import inner membrane translocase subunit Tim10-like K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
D 115456897 mitochondrial import inner membrane translocase subunit Tim10 K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
D 115468237 TIMM10B; mitochondrial import inner membrane translocase subunit Tim10 B K17779 TIM10B; mitochondrial import inner membrane translocase subunit TIM10B
C TIM8/13 complex
D 115474147 TIMM8A; mitochondrial import inner membrane translocase subunit Tim8 A K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 115481719 TIMM8B; mitochondrial import inner membrane translocase subunit Tim8 B K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D 115481230 TIMM13; mitochondrial import inner membrane translocase subunit Tim13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D 115471853 CHCHD4; mitochondrial intermembrane space import and assembly protein 40 K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D 115475921 GFER; FAD-linked sulfhydryl oxidase ALR K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D 115482635 MICOS10; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 115461334 IMMT; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
D 115480320 MICOS13; MICOS complex subunit MIC13 K24624 MICOS13; MICOS complex subunit MIC13
D 115478919 CHCHD3; MICOS complex subunit MIC19 K17563 CHCHD3; MICOS complex subunit MIC19
D 115472521 MICOS complex subunit MIC19-like K17563 CHCHD3; MICOS complex subunit MIC19
D 115473027 CHCHD6; MICOS complex subunit MIC25 K17564 CHCHD6; MICOS complex subunit MIC25
D 115469513 APOO; MICOS complex subunit MIC26 K24625 APOO; MICOS complex subunit MIC26
D 115473921 APOOL; MICOS complex subunit MIC27 isoform X1 K24626 APOOL; MICOS complex subunit MIC27
C MICOS complex (yeast)
D 115482635 MICOS10; MICOS complex subunit MIC10 K17784 MICOS10; MICOS complex subunit MIC10
D 115461334 IMMT; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
C TIM22 complex
D 115456538 TIMM22; mitochondrial import inner membrane translocase subunit Tim22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
C TIM23 complex
D 115470265 TIMM23B; putative mitochondrial import inner membrane translocase subunit Tim23B K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D 115481619 TIMM17A; mitochondrial import inner membrane translocase subunit Tim17-A K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 115463437 mitochondrial import inner membrane translocase subunit Tim17-B K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 115463441 mitochondrial import inner membrane translocase subunit Tim17-B K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D 115476415 TIMM21; mitochondrial import inner membrane translocase subunit Tim21 K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
D 115479624 TIMM50; mitochondrial import inner membrane translocase subunit TIM50 K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
D 115470374 MCU; calcium uniporter protein, mitochondrial K20858 MCU; calcium uniporter protein, mitochondrial
D 115468528 MICU2; calcium uptake protein 2, mitochondrial isoform X1 K22828 MICU2; calcium uptake protein 2, mitochondrial
D 115461178 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial isoform X1 K22829 MCUB; calcium uniporter regulatory subunit MCUb, mitochondrial
D 115460137 SMDT1; essential MCU regulator, mitochondrial K22830 SMDT1; essential MCU regulator, mitochondrial
D 115475466 MCUR1; mitochondrial calcium uniporter regulator 1 isoform X1 K22137 MCUR1; mitochondrial calcium uniporter regulator 1
C Other inner membrane factors
D 115461354 LETM1; LOW QUALITY PROTEIN: mitochondrial proton/calcium exchanger protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D 115468732 IMMP1L; mitochondrial inner membrane protease subunit 1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D 115479354 IMMP2L; mitochondrial inner membrane protease subunit 2 isoform X1 K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D 115468421 TMEM126A; transmembrane protein 126A K18157 TMEM126A; transmembrane protein 126A
D 115466677 MPC1; mitochondrial pyruvate carrier 1 K22138 MPC1; mitochondrial pyruvate carrier 1
D 115470583 MPC2; mitochondrial pyruvate carrier 2 K22139 MPC2; mitochondrial pyruvate carrier 2
D 115480061 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22759 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
B Matrix
C MMC/PAM proteins
D 115480023 mitochondrial import inner membrane translocase subunit TIM44-like K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D 115480959 LOW QUALITY PROTEIN: mitochondrial import inner membrane translocase subunit TIM44-like K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D 115475684 HSPA9; LOW QUALITY PROTEIN: stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 115461394 GRPEL1; grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
D 115475813 GRPEL2; grpE protein homolog 2, mitochondrial isoform X1 K03687 GRPE; molecular chaperone GrpE
D 115460034 DNAJC19; mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D 115473030 PMPCA; mitochondrial-processing peptidase subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D 115478802 PMPCB; LOW QUALITY PROTEIN: mitochondrial-processing peptidase subunit beta K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D 115468534 MIPEP; mitochondrial intermediate peptidase K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D 115473835 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D 115476120 DNAJA3; dnaJ homolog subfamily A member 3, mitochondrial isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
D 115472105 TAMM41; phosphatidate cytidylyltransferase, mitochondrial K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D 115472210 DNLZ; DNL-type zinc finger protein isoform X1 K17808 ZIM17; mitochondrial protein import protein ZIM17
D 115476093 persulfide dioxygenase ETHE1, mitochondrial-like K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D 115457647 persulfide dioxygenase ETHE1, mitochondrial-like K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D 115473939 polymerase delta-interacting protein 2-like K17809 POLDIP2; polymerase delta-interacting protein 2
D 115482655 POLDIP2; polymerase delta-interacting protein 2 K17809 POLDIP2; polymerase delta-interacting protein 2
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D 115474058 CREB1; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 115463079 GFM2; LOW QUALITY PROTEIN: ribosome-releasing factor 2, mitochondrial K02355 fusA; elongation factor G
D 115479138 GFM1; elongation factor G, mitochondrial K02355 fusA; elongation factor G
D 115466821 SP1; transcription factor Sp1 K04684 SP1; transcription factor Sp1
D 115477703 YY1; LOW QUALITY PROTEIN: transcriptional repressor protein YY1 K09201 YY; transcription factor YY
D 115458035 GABPB2; GA-binding protein subunit beta-2 K09454 GABPB; GA-binding protein transcription factor, beta
D 115459812 GABPB1; GA-binding protein subunit beta-1 isoform X1 K09454 GABPB; GA-binding protein transcription factor, beta
D 115470152 TFAM; transcription factor A, mitochondrial K11830 TFAM; transcription factor A, mitochondrial
C Nuclear respiratory factors
D 115478582 NRF1; nuclear respiratory factor 1 isoform X1 K11831 NRF1; nuclear respiratory factor 1
D 115475110 NFE2L2; LOW QUALITY PROTEIN: nuclear factor erythroid 2-related factor 2 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
D 115474619 metallothionein-like K14739 MT1_2; metallothionein 1/2
C Coactivators
D 115461441 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
D 115475964 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
D 115479437 CRTC1; CREB-regulated transcription coactivator 1 isoform X1 K15309 CRTC1; CREB-regulated transcription coactivator 1
D 115475663 CREBBP; CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 115470105 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C Proteins involved in Fe-S cluster biogenesis
D 115476948 NFS1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 115480725 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D 115463387 FXN; frataxin, mitochondrial isoform X1 K19054 FXN; frataxin [EC:1.16.3.1]
D 115467882 FDX1; adrenodoxin, mitochondrial K22070 FDX1; ferredoxin-1, mitochondrial
D 115473715 adrenodoxin-like K22071 FDX2; ferredoxin-2, mitochondrial
D 115461851 ferredoxin-2, mitochondrial-like isoform X1 K22071 FDX2; ferredoxin-2, mitochondrial
D 115462854 ferredoxin-2, mitochondrial-like K22071 FDX2; ferredoxin-2, mitochondrial
D 115473395 FDXR; NADPH:adrenodoxin oxidoreductase, mitochondrial K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D 115475684 HSPA9; LOW QUALITY PROTEIN: stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
D 115479991 HSCB; iron-sulfur cluster co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
D 115476562 SIL1; nucleotide exchange factor SIL1 K14001 SIL1; nucleotide exchange factor SIL1
D 115478009 GLRX5; glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
D 115463294 ISCA1; iron-sulfur cluster assembly 1 homolog, mitochondrial K22063 ISCA1; iron-sulfur cluster assembly 1
D 115477412 ISCA2; iron-sulfur cluster assembly 2 homolog, mitochondrial K22072 ISCA2; iron-sulfur cluster assembly 2
D 115471562 putative transferase CAF17, mitochondrial K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D 115459521 LOW QUALITY PROTEIN: putative transferase CAF17, mitochondrial K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D 115469344 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1 K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D 115457758 BOLA1; bolA-like protein 1 isoform X1 K22066 BOLA1; BolA-like protein 1
D 115469290 BOLA3; bolA-like protein 3 isoform X1 K22075 BOLA3; BolA-like protein 3
D 115475712 SFXN1; sideroflexin-1 isoform X1 K23500 SFXN1_3; sideroflexin-1/3
D 115471101 SFXN3; sideroflexin-3 isoform X1 K23500 SFXN1_3; sideroflexin-1/3
D 115469876 SFXN4; sideroflexin-4 K23502 SFXN4; sideroflexin-4
D 115461254 SFXN5; sideroflexin-5 isoform X1 K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D 115469040 CPT1A; LOW QUALITY PROTEIN: carnitine O-palmitoyltransferase 1, liver isoform K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 115466616 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform isoform X1 K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D 115478438 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1 K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
D 115478619 DHTKD1; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
D 115467265 FBXL4; F-box/LRR-repeat protein 4 isoform X1 K10270 FBXL4; F-box and leucine-rich repeat protein 4
D 115462014 HCFC1; LOW QUALITY PROTEIN: host cell factor 1 K14966 HCFC1; host cell factor 1
D 115477501 HCFC2; host cell factor 2 isoform X1 K27390 HCFC2; host cell factor 2
D 115461377 HTT; huntingtin K04533 HD; huntingtin
D 115477511 LOW QUALITY PROTEIN: steroid hormone receptor ERR2-like K08553 NR3B2; estrogen-related receptor beta
D 115477950 LOW QUALITY PROTEIN: steroid hormone receptor ERR2-like K08553 NR3B2; estrogen-related receptor beta
D 115480873 ESRRA; steroid hormone receptor ERR1 K08554 NR3B3; estrogen-related receptor gamma
D 115465507 ESRRG; estrogen-related receptor gamma isoform X1 K08554 NR3B3; estrogen-related receptor gamma
D 115470732 NRIP1; nuclear receptor-interacting protein 1 K17965 NRIP1; nuclear receptor-interacting protein 1
D 115462958 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 115472230 PRKAA2; LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 115480732 LONP1; lon protease homolog, mitochondrial K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D 115470176 SIRT1; NAD-dependent protein deacetylase sirtuin-1 K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
D 115466856 SERAC1; protein SERAC1 isoform X1 K23504 SERAC1; protein SERAC1
D 115463417 UXT; protein UXT K26537 UXT; protein UXT
D 115456625 PERM1; LOW QUALITY PROTEIN: PGC-1 and ERR-induced regulator in muscle protein 1 K26738 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D 115477305 NDUFAF1; complex I intermediate-associated protein 30, mitochondrial K18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1
D 115462271 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 K18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
D 115472144 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform X1 K09008 NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
D 115465234 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 K18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
D 115465684 NDUFAF5; arginine-hydroxylase NDUFAF5, mitochondrial isoform X1 K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D 115479102 NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1 K18163 NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6
D 115465043 NDUFAF7; protein arginine methyltransferase NDUFAF7, mitochondrial isoform X1 K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D 115473534 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
D 115472351 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8-like K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
D 115466025 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
D 115471871 ACAD9; acyl-CoA dehydrogenase family member 9, mitochondrial K15980 ACAD9; acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-]
D 115477551 NUBPL; iron-sulfur protein NUBPL isoform X1 K03593 mrp; ATP-binding protein involved in chromosome partitioning
D 115481776 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1 K18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1
D 115467308 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial K23164 RTN4IP1; reticulon-4-interacting protein 1, mitochondrial
D 115470602 TIMMDC1; complex I assembly factor TIMMDC1, mitochondrial isoform X1 K23505 TIMMDC1; complex I assembly factor TIMMDC1
C Complex-II assembly factors
D 115463060 SDHAF1; succinate dehydrogenase assembly factor 1, mitochondrial K18167 SDHAF1; succinate dehydrogenase assembly factor 1
D 115468964 SDHAF2; succinate dehydrogenase assembly factor 2, mitochondrial K18168 SDHAF2; succinate dehydrogenase assembly factor 2
C Complex-III assembly factors
D 115474511 mitochondrial chaperone BCS1 K08900 BCS1; mitochondrial chaperone BCS1
D 115456710 TTC19; tetratricopeptide repeat protein 19, mitochondrial K18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial
D 115463249 LYRM7; complex III assembly factor LYRM7 isoform X1 K18170 LYRM7; complex III assembly factor LYRM7
D 115476618 ubiquinol-cytochrome-c reductase complex assembly factor 1 K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D 115481324 ubiquinol-cytochrome-c reductase complex assembly factor 2 K17682 MNF1; mitochondrial nucleoid factor 1
D 115473054 SMIM4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
D 115477683 C9H12orf73; uncharacterized protein C12orf73 homolog K27341 UQCC6; ubiquinol-cytochrome c reductase complex assembly factor 6
C Complex-IV assembly factors
D 115466182 CMC1; COX assembly mitochondrial protein homolog K18171 CMC1; COX assembly mitochondrial protein 1
D 115470894 CMC2; COX assembly mitochondrial protein 2 homolog K18172 CMC2; COX assembly mitochondrial protein 2
D 115459604 COX assembly mitochondrial protein 2 homolog K18172 CMC2; COX assembly mitochondrial protein 2
D 115460163 cytochrome c oxidase assembly factor 1 homolog K18173 COA1; cytochrome c oxidase assembly factor 1
D 115481861 LOW QUALITY PROTEIN: cytochrome c oxidase assembly factor 3 homolog, mitochondrial K18175 CCDC56; cytochrome c oxidase assembly factor 3, animal type
D 115468370 cytochrome c oxidase assembly factor 4 homolog, mitochondrial-like K18177 COA4; cytochrome c oxidase assembly factor 4
D 115468031 cytochrome c oxidase assembly factor 5 K18178 COA5; cytochrome c oxidase assembly factor 5
D 115480394 cytochrome c oxidase assembly factor 6 homolog K18179 COA6; cytochrome c oxidase assembly factor 6
D 115472251 cytochrome c oxidase assembly factor 7 K18180 COA7; cytochrome c oxidase assembly factor 7
D 115473428 cytochrome c oxidase assembly protein COX11, mitochondrial K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D 115466757 cytochrome c oxidase assembly protein COX14 K18181 COX14; cytochrome c oxidase assembly factor 14
D 115470054 cytochrome c oxidase assembly protein COX15 homolog isoform X1 K02259 COX15; heme a synthase [EC:1.17.99.9]
D 115477628 cytochrome c oxidase assembly protein COX16 homolog, mitochondrial K18182 COX16; cytochrome c oxidase assembly protein subunit 16
D 115470655 cytochrome c oxidase copper chaperone K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D 115460410 LOW QUALITY PROTEIN: cytochrome c oxidase assembly protein COX18, mitochondrial-like K17797 COX18; mitochondrial inner membrane protein COX18
D 115458885 cytochrome c oxidase assembly protein COX18, mitochondrial-like K17797 COX18; mitochondrial inner membrane protein COX18
D 115475783 cytochrome c oxidase assembly protein COX19 K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D 115465758 cytochrome c oxidase assembly protein COX20, mitochondrial isoform X1 K18184 COX20; cytochrome c oxidase assembly protein subunit 20
D 115476332 MSS51; putative protein MSS51 homolog, mitochondrial K17656 MSS51; mitochondrial splicing suppressor protein 51
D 115466174 protein PET100 homolog, mitochondrial-like K18186 PET100; protein PET100, animal type
D 115459440 protein PET100 homolog, mitochondrial-like K18186 PET100; protein PET100, animal type
D 115465629 protein PET117 homolog, mitochondrial isoform X1 K18188 PET117; protein PET117
D 115458107 OXA1L; mitochondrial inner membrane protein OXA1L isoform X1 K03217 yidC; YidC/Oxa1 family membrane protein insertase
D 115473084 surfeit locus protein 1 K14998 SURF1; surfeit locus 1 family protein
D 115473215 protein SCO1 homolog, mitochondrial K07152 SCO1; protein SCO1
D 115478725 protein SCO2 homolog, mitochondrial K23755 SCO2; protein SCO2
D 115463696 translational activator of cytochrome c oxidase 1 K18189 TACO1; translational activator of cytochrome c oxidase 1
D 115465368 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial isoform X1 K17964 LRPPRC; leucine-rich PPR motif-containing protein, mitochondrial
D 115477392 apoptogenic protein 1, mitochondrial K23506 APOPT1; apoptogenic protein 1
D 115473054 SMIM4; small integral membrane protein 4 K27340 UQCC5; ubiquinol-cytochrome c reductase complex assembly factor 5
D 115479894 TMEM223; transmembrane protein 223 K27342 TMEM223; transmembrane protein 223
C Complex-V assembly factors
D 115471934 ATPAF1; ATP synthase mitochondrial F1 complex assembly factor 1 K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
D 115475443 ATPAF2; ATP synthase mitochondrial F1 complex assembly factor 2 K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D 115460391 TMEM70; transmembrane protein 70, mitochondrial K17966 TMEM70; transmembrane protein 70, mitochondrial
D 115469987 ATP5MD; ATP synthase membrane subunit DAPIT, mitochondrial K18194 USMG5; up-regulated during skeletal muscle growth protein 5
B Mitochondrial dynamics
C Fission and Fusion factors
D 115479131 MFN1; mitofusin-1 K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
D 115482486 MFN2; mitofusin-2 isoform X1 K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D 115479301 OPA1; dynamin-like 120 kDa protein, mitochondrial isoform X1 K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
D 115480908 OPA3; optic atrophy 3 protein K23166 OPA3; optic atrophy 3 protein
D 115479864 TRIAP1; TP53-regulated inhibitor of apoptosis 1 K17968 TRIAP1; TRIAP1/MDM35 family protein
D 115479285 PARL; presenilins-associated rhomboid-like protein, mitochondrial isoform X1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 115481830 BAK1; bcl-2 homologous antagonist/killer K14021 BAK; Bcl-2 homologous antagonist/killer
D 115466621 BAX; apoptosis regulator BAX K02159 BAX; apoptosis regulator BAX
D 115463583 dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 115477139 DNM1L; dynamin-1-like protein isoform X1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 115457515 mitochondrial fission 1 protein-like isoform X1 K17969 FIS1; mitochondrial fission 1 protein
D 115474325 SUMO1; small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
D 115474468 SUMO3; small ubiquitin-related modifier 3 K12160 SUMO; small ubiquitin-related modifier
D 115481713 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
D 115473380 SUMO2; small ubiquitin-related modifier 2 isoform X1 K12160 SUMO; small ubiquitin-related modifier
D 115471765 SH3GLB1; endophilin-B1 isoform X1 K11248 SH3GLB1; endophilin-B1
D 115468858 MTCH2; mitochondrial carrier homolog 2 K17885 MTCH; mitochondrial carrier
D 115481428 MTCH1; mitochondrial carrier homolog 1 isoform X1 K17885 MTCH; mitochondrial carrier
D 115474223 mitochondrial fission factor-like isoform X1 K22076 MFF; mitochondrial fission factor
D 115478952 MFF; mitochondrial fission factor isoform X1 K22076 MFF; mitochondrial fission factor
D 115460392 GDAP1; ganglioside-induced differentiation-associated protein 1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 115475396 GDAP1L1; ganglioside-induced differentiation-associated protein 1-like 1 isoform X1 K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
D 115481738 VAT1; synaptic vesicle membrane protein VAT-1 homolog isoform X1 K23167 VAT1; synaptic vesicle membrane protein VAT-1
D 115475890 MIEF2; mitochondrial dynamics protein MID49 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 115473437 MIEF1; mitochondrial dynamics protein MID51 K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
D 115461975 mitochondrial cardiolipin hydrolase-like K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D 115475939 PLD6; mitochondrial cardiolipin hydrolase K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
D 115473156 MIGA2; mitoguardin 2 isoform X1 K27289 MIGA; mitoguardin
D 115472684 MIGA1; mitoguardin 1 K27289 MIGA; mitoguardin
C Actin cytoskeleton organization
D 115473528 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
D 115475893 actin-85C-like K05692 ACTB_G1; actin beta/gamma 1
D 115476970 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
D 115476971 actin, cytoplasmic 1-like isoform X1 K05692 ACTB_G1; actin beta/gamma 1
D 115476972 actin, cytoplasmic 1-like K05692 ACTB_G1; actin beta/gamma 1
D 115476973 actin, cytoplasmic 1-like K05692 ACTB_G1; actin beta/gamma 1
D 115476974 actin-like K05692 ACTB_G1; actin beta/gamma 1
D 115476975 actin, cytoplasmic 1-like K05692 ACTB_G1; actin beta/gamma 1
D 115477271 actin, cytoplasmic 1-like K05692 ACTB_G1; actin beta/gamma 1
D 115465618 NAA20; N-alpha-acetyltransferase 20 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D 115479946 LOW QUALITY PROTEIN: N-alpha-acetyltransferase 25, NatB auxiliary subunit-like K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
D 115479948 N-alpha-acetyltransferase 25, NatB auxiliary subunit-like K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D 115481782 PHB; LOW QUALITY PROTEIN: prohibitin K17080 PHB1; prohibitin 1
D 115457868 PHB2; prohibitin-2 K17081 PHB2; prohibitin 2
D 115477961 KTN1; kinectin isoform X1 K17975 KTN1; kinectin
C Retention of mitochondria
D 115463583 dynamin-1-like protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 115477139 DNM1L; dynamin-1-like protein isoform X1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D 115462879 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
D 115459487 MYO5A; LOW QUALITY PROTEIN: unconventional myosin-Va K10357 MYO5; myosin V
D 115459488 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
D 115474611 XIAP; E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 115479851 DIABLO; diablo homolog, mitochondrial isoform X1 K10522 DIABLO; diablo
C Morphogenesis factors
D 115461574 SNX25; LOW QUALITY PROTEIN: sorting nexin-25 K17887 SNX25; sorting nexin-25
D 115473447 RHOT1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 115461334 IMMT; MICOS complex subunit MIC60 isoform X1 K17785 IMMT; MICOS complex subunit MIC60
D 115480463 MTFP1; mitochondrial fission process protein 1 K17981 MTFP1; mitochondrial fission process protein 1
D 115456953 DAP3; 28S ribosomal protein S29, mitochondrial K17408 DAP3; small subunit ribosomal protein S29
D 115459191 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
D 115479789 OXR1; oxidation resistance protein 1 isoform X1 K25437 OXR1; oxidation resistance protein 1
D 115457665 MSTO1; protein misato homolog 1 K27320 MSTO1; protein misato
B Mitophagy factors
C Autophagy-related proteins
D 115477474 ATG2B; autophagy-related protein 2 homolog B isoform X1 K17906 ATG2; autophagy-related protein 2
D 115479665 ATG2A; autophagy-related protein 2 homolog A isoform X1 K17906 ATG2; autophagy-related protein 2
D 115469506 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D 115474625 ATG4A; cysteine protease ATG4A K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 115478492 ATG4B; cysteine protease ATG4B isoform X1 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 115466060 ATG4D; cysteine protease ATG4D K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 115472435 ATG4C; LOW QUALITY PROTEIN: cysteine protease ATG4C K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D 115467305 ATG5; autophagy protein 5 isoform X1 K08339 ATG5; autophagy-related protein 5
D 115481969 BECN1; beclin-1 K08334 BECN; beclin
D 115471865 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D 115471012 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
D 115457775 gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
D 115458372 GABARAP; gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
D 115458892 gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
D 115474525 ATG9A; autophagy-related protein 9A isoform X1 K17907 ATG9; autophagy-related protein 9
D 115465200 ATG9B; autophagy-related protein 9B K17907 ATG9; autophagy-related protein 9
D 115463116 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D 115466487 ATG12; ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
D 115477733 ATG14; beclin 1-associated autophagy-related key regulator K17889 ATG14L; beclin 1-associated autophagy-related key regulator
D 115479329 ATG16L1; LOW QUALITY PROTEIN: autophagy-related protein 16-1 K17890 ATG16L1; autophagy-related protein 16-1
D 115467827 ATG16L2; autophagy-related protein 16-2 K20868 ATG16L2; autophagy-related protein 16-2
D 115475830 WIPI2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 K17908 WIPI1_2; autophagy-related protein 18
D 115473484 WIPI1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 K17908 WIPI1_2; autophagy-related protein 18
D 115466922 vacuolar protein 8-like K08332 VAC8; vacuolar protein 8
C Parkin-dependent mechanism factors
D 115465913 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 115475572 CLEC16A; protein CLEC16A isoform X1 K19513 CLEC16A; protein CLEC16A
D 115479285 PARL; presenilins-associated rhomboid-like protein, mitochondrial isoform X1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D 115476938 SQSTM1; sequestosome-1 isoform X1 K14381 SQSTM1; sequestosome 1
D 115458800 sequestosome-1-like isoform X1 K14381 SQSTM1; sequestosome 1
D 115469671 TAX1BP1; LOW QUALITY PROTEIN: tax1-binding protein 1 K21347 TAX1BP1; Tax1-binding protein 1
D 115482031 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2 isoform X1 K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
D 115468831 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1 isoform X1 K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
C Parkin-independent mechanism factors
D 115468833 ATG13; LOW QUALITY PROTEIN: autophagy-related protein 13 K08331 ATG13; autophagy-related protein 13
D 115479510 ULK1; serine/threonine-protein kinase ULK1 K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
D 115482362 ULK2; serine/threonine-protein kinase ULK2 isoform X1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D 115477462 RB1CC1; RB1-inducible coiled-coil protein 1 isoform X1 K17589 RB1CC1; RB1-inducible coiled-coil protein 1
D 115477177 HSP90AA1; heat shock protein HSP 90-alpha K04079 HSP90A; molecular chaperone HtpG
D 115465334 HSP90AB1; heat shock protein HSP 90-beta K04079 HSP90A; molecular chaperone HtpG
D 115458986 heat shock protein HSP 90-beta-like K04079 HSP90A; molecular chaperone HtpG
D 115466069 CDC37; hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
D 115475366 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 115472575 SMURF2; E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
D 115469324 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1 K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
D 115474077 FUNDC2; FUN14 domain-containing protein 2 isoform X1 K17986 FUNDC1; FUN14 domain-containing protein 1
D 115468159 FUNDC1; FUN14 domain-containing protein 1 K17986 FUNDC1; FUN14 domain-containing protein 1
C Other mitophagy factors
D 115462958 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 115472230 PRKAA2; LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D 115480577 microtubule-associated proteins 1A/1B light chain 3C-like K10435 MAP1LC; microtubule-associated protein 1 light chain
D 115475705 MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A K10435 MAP1LC; microtubule-associated protein 1 light chain
D 115464850 MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C K10435 MAP1LC; microtubule-associated protein 1 light chain
D 115470930 MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B K10435 MAP1LC; microtubule-associated protein 1 light chain
D 115481349 LOW QUALITY PROTEIN: next to BRCA1 gene 1 protein-like K17987 NBR1; next to BRCA1 gene 1 protein
D 115481352 next to BRCA1 gene 1 protein-like isoform X1 K17987 NBR1; next to BRCA1 gene 1 protein
D 115475897 TECPR1; tectonin beta-propeller repeat-containing protein 1 isoform X1 K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
D 115477463 ZFYVE1; zinc finger FYVE domain-containing protein 1 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 115479531 zinc finger FYVE domain-containing protein 1-like isoform X1 K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
D 115481728 COASY; bifunctional coenzyme A synthase isoform X1 K02318 COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
D 115473358 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
D 115470831 C5H19orf12; protein C19orf12 homolog K23168 MPAN; protein MPAN
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024