+E Polyketide biosynthesis proteins KO
#
Polyketide Biosynthesis Proteins - Mycobacterium intracellulare subsp. yongonense
%
!
APolyketide synthase (PKS)
B Modular type I PKS
C cis-AT PKS
D Erythronolide PKS
D Oleandomycin synthase
D Pikromycin PKS
D Avermectin PKS
D Tylactone synthase
D Protomycinolide IV synthase
D Niddamycin PKS
D Rapamycin PKS
D Immunomycin PKS
D Ansamitocin PKS
D Rifamycin PKS
D Polyene macrolide PKS
D Pimaricinolide synthase
D Candicidin PKS
D Soraphen PKS
D Stigmatellin PKS
D Mycolactone PKS
D Coelimycin PKS
D Aureothin PKS
D Spectinabilin PKS
D Phthiocerol / Phenolphthiocerol PKS
C trans-AT PKS
D Bacillanene hybrid PKS-NRPS
D Chivosazol hybrid PKS-NRPS
E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133]
D Macrolactin PKS
D Difficidin PKS
D Rhizoxin hybrid PKS-NRPS
D Myxovirescin hybrid PKS-NRPS
E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932]
D Albicidin synthase, hybrid PKS-NRPS
E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516]
E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523]
D Etnangien PKS
E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193]
B Iterative type I PKS
C Fungal nonreducing PKS (NR-PKS)
C Fungal partially reducing PKS (PR-PKS)
C Fungal highly reducing PKS (HR-PKS)
C Fungal hybrid type
D Zearalenone synthase
D Asperfuranone NR/HR-PKS
E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034]
E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036]
C Bacterial type
D OEM_22900 erythronolide synthase, modules 3 and 4 K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295]
B Type II PKS
C C9-C14 cyclized polyketide type
D Spore pigment PKS
C C7-C14 cyclized polyketide type
D Octaketide PKS
D Nonaketide PKS
D Decaketide PKS
B Type III PKS
C Plant type
C Fungal type
C Bacterial type
D OEM_12030 transferase K16167 bpsA; alkylresorcinol/alkylpyrone synthase
D OEM_28650 pks11 protein K16167 bpsA; alkylresorcinol/alkylpyrone synthase
D OEM_28690 pks10 K16167 bpsA; alkylresorcinol/alkylpyrone synthase
D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550]
D ------ arsC; alkylpyrone synthase [AVN:Avin_29530]
B PKS-NRPS hybrid
C Bacterial type (modular)
D Myxalamid hybrid PKS-NRPS
D Myxothiazol hybrid PKS-NRPS
E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019]
D Coronatine hybrid PKS-NRPS
D Microcystin synthetase
D Epothilone synthetase
D Bleomycin synthetase
D Colibactin synthetase
C Fungal type (trans-ER, iterative)
D Aspyridone synthetase
C Fungal type (iterative)
#
ANonribosomal peptide synthetase (NRPS)
B Linear NRPS
C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545]
C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500]
C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000]
C ACV synthetase
C Bacitracin synthetase
C Viomycin synthetase
C Pristinamycin I synthetase
C Tyrocidine synthetase
C Surfactin family lipopeptide synthetase
C Iturin family lipopeptide synthetase
C Fengycin family lipopeptide synthetase
C Arthrofactin type cyclic lipopeptide synthetase
C Vancomycin synthetase
C Nocardicin synthetase
D OEM_17840 hypothetical protein K05375 mbtH; MbtH protein
D OEM_27430 hypothetical protein K05375 mbtH; MbtH protein
C Bialaphos synthetase
C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase
B Iterative NRPS
C Enterobactin synthetase
D OEM_35540 sfp-type phosphopantetheinyl transferase K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7]
C Bacillibactin synthetase
C Gramicidin synthetase
B Nonlinear NRPS
C Yersiniabactin synthetase
C Pyochelin synthetase
C Mycobactin synthetase
D OEM_17760 2,3-dihydroxybenzoate-AMP ligase K04787 mbtA; mycobactin salicyl-AMP ligase [EC:6.3.2.-]
D OEM_17770 MbtB protein K04788 mbtB; mycobactin phenyloxazoline synthetase
D OEM_17790 erythronolide synthase, modules 1 and 2 K04790 mbtC; mycobactin polyketide synthetase MbtC
D OEM_28080 polyketide synthase MbtC K04790 mbtC; mycobactin polyketide synthetase MbtC
D OEM_17800 MbtD protein K04791 mbtD; mycobactin polyketide synthetase MbtD
D OEM_28090 polyketide synthase MbtD K04791 mbtD; mycobactin polyketide synthetase MbtD
D OEM_17810 linear gramicidin synthetase subunit D K04789 mbtE; mycobactin peptide synthetase MbtE
D OEM_28050 non-ribosomal peptide synthetase MbtE K04789 mbtE; mycobactin peptide synthetase MbtE
D OEM_17820 putative sulfotransferase K04792 mbtF; mycobactin peptide synthetase MbtF
D OEM_28040 non-ribosomal peptide synthetase MbtF K04792 mbtF; mycobactin peptide synthetase MbtF
C Vibriobactin synthetase
C Myxochelin synthetase
C Petrobacin synthetase
C Syringomycin synthetase
C Vanchrobactin synthetase
C Isonitrile lipopeptide synthase
#
APolyketide tailoring proteins
B Hydrolase
B Ketoreductase
B Oxygenase
C OEM_19780 hypothetical protein K21159 sgcF; epoxide hydrolase
C OEM_19650 FAD binding domain-containing protein K14672 whiEVIII; putative polyketide hydroxylase
B Methylase
C OEM_12020 isoprenylcysteine carboxyl methyltransferase (icmt) family protein K16168 bpsB; methyltransferase
B Glycosyltransferase
B Halogenase
B beta-Branched incorporating proteins
B Others
#
ANonribosomal peptide tailoring proteins
B Reductase
B Thioesterase
B Oxygenase
C OEM_17830 MbtG protein K04793 mbtG; mycobactin lysine-N-oxygenase
B Glycosyltransferase
C OEM_24180 hypothetical protein K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310]
B Aminotransferase
B Others
!
#
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2025