+C Lipid biosynthesis protein KO
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Lipid Biosynthesis Proteins - Maylandia zebra (zebra mbuna)
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AFatty acid synthase
B Animal type
C 101485706 fasn; fatty acid synthase K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
B Yeast type
B Bacteria type
B Component type
C 101482890 malonyl-CoA-acyl carrier protein transacylase, mitochondrial K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 101466558 oxsm; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
C 101464359 hsd20b2; hydroxysteroid (20-beta) dehydrogenase 2 K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
C 101469758 hsd17b12b; very-long-chain 3-oxoacyl-CoA reductase-B K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
C 101474165 hsd17b12a; very-long-chain 3-oxoacyl-CoA reductase-A K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
C 101467683 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101468089 hacd3; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101472136 hacd4; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101479872 hacd1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101481030 hacd2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
C 101480248 peroxisomal trans-2-enoyl-CoA reductase isoform X1 K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
C 101480535 peroxisomal trans-2-enoyl-CoA reductase isoform X1 K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
C 101469805 tecrl2a; very-long-chain enoyl-CoA reductase K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 101471785 tecra; very-long-chain enoyl-CoA reductase K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 101483996 tecrb; trans-2,3-enoyl-CoA reductase b K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
C 101474377 olah; S-acyl fatty acid synthase thioesterase, medium chain K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
C 101472327 lysosomal thioesterase PPT2 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 101475534 ppt2b; lysosomal thioesterase PPT2 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 101479416 ppt1; palmitoyl-protein thioesterase 1 isoform X1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 143419426 lysosomal thioesterase PPT2-like K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
C 101478905 peroxisomal succinyl-coenzyme A thioesterase isoform X4 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101480502 peroxisomal succinyl-coenzyme A thioesterase K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101483360 acyl-coenzyme A thioesterase 1 isoform X1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101483381 acyl-coenzyme A thioesterase 2, mitochondrial K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101484556 acyl-coenzyme A thioesterase 1 isoform X2 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101487854 acyl-coenzyme A thioesterase 1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 106676645 acyl-coenzyme A thioesterase 5 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 143413724 acyl-coenzyme A thioesterase 2, mitochondrial-like K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
C 101466734 acot7; cytosolic acyl coenzyme A thioester hydrolase isoform X2 K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
C 101467284 acot9.1; acyl-coenzyme A thioesterase 9, mitochondrial isoform X1 K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
C 101475851 acot11a; acyl-coenzyme A thioesterase 11 isoform X1 K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
C 101482447 acot11b; acyl-coenzyme A thioesterase 11b K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
C 101464402 acot13; acyl-coenzyme A thioesterase 13 K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
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ADesaturase
B First
C 101478888 scd; acyl-CoA desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
B Omega
B Front-end
C 101473241 acyl-CoA Delta-4 desaturase K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
C 101473919 acyl-CoA Delta-4 desaturase K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
C 101474216 acyl-CoA Delta-4 desaturase K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
B Sphingolipid
C 101475928 degs1; sphingolipid delta(4)-desaturase DES1 isoform X1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
C 101481400 degs2; sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
B Other
C 101475196 fads6; fatty acid desaturase 6 K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-]
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AElongase
B LCFA
B PUFA
C 101477957 elovl1b; elongation of very long chain fatty acids protein 1b K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
C 101481208 elovl1a; elongation of very long chain fatty acids protein 1a isoform X1 K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
C 101477514 very long chain fatty acid elongase 4 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101479286 elovl8a; ELOVL fatty acid elongase 8a K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101481327 elovl4a; elongation of very long chain fatty acids protein 4a K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101483690 elovl8b; ELOVL fatty acid elongase 8b isoform X1 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 112432417 very long chain fatty acid elongase 4-like K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 112434813 very long chain fatty acid elongase 4-like K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
C 101471581 elovl5; very long chain fatty acid elongase 5 K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
C 101468487 elovl6l; very long chain fatty acid elongase 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
C 101486796 elovl6; very long chain fatty acid elongase 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
C 101487029 very long chain fatty acid elongase 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
C 101473791 elovl7a; elongation of very long chain fatty acids protein 7a K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
B Unclassified
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APolyketide synthase
B Modular PKS
B Component type
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AAcyl-CoA ligase
B Short/medium chain acyl-CoA ligase
C 101471566 acss1; acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101472605 acss2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101484602 acss2l; acyl-CoA synthetase short chain family member 2 like K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101486165 acetyl-coenzyme A synthetase 2-like, mitochondrial K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 101470984 acss3; acyl-CoA synthetase short-chain family member 3, mitochondrial K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
C 101470885 aacs; acetoacetyl-CoA synthetase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
C 101484291 acsf2; medium-chain acyl-CoA ligase ACSF2, mitochondrial K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
C 101486716 medium-chain acyl-CoA ligase ACSF2, mitochondrial isoform X1 K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
B Long/very long chain acyl-CoA ligase
C 101463984 acsl3b; long-chain-fatty-acid--CoA ligase 3b K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101464145 acsl5; long-chain-fatty-acid--CoA ligase 5 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101466073 acsl6; long-chain-fatty-acid--CoA ligase 6 isoform X1 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101470568 acsl2; long-chain-fatty-acid--CoA ligase 1 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101471617 acsl4a; long-chain-fatty-acid--CoA ligase 4 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101472181 acsl3a; long-chain-fatty-acid--CoA ligase 3a K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101481632 acsl1a; long-chain-fatty-acid--CoA ligase 1a isoform X1 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101487205 long-chain-fatty-acid--CoA ligase 1 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101469094 acsbg2; long-chain-fatty-acid--CoA ligase ACSBG2 K15013 ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101474583 long-chain-fatty-acid--CoA ligase ACSBG2 isoform X2 K15013 ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101477283 acsbg1; long-chain-fatty-acid--CoA ligase ACSBG1 K15013 ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 101464164 long-chain fatty acid transport protein 1 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 101478522 slc27a1a; long-chain fatty acid transport protein 1a K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 101487968 slc27a4; long-chain fatty acid transport protein 4 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
C 101464372 long-chain fatty acid transport protein 2 isoform X1 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101469394 zgc:158482; long-chain fatty acid transport protein 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101472508 slc27a2; long-chain fatty acid transport protein 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101472789 long-chain fatty acid transport protein 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101473083 long-chain fatty acid transport protein 2 isoform X1 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
C 101485866 long-chain fatty acid transport protein 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
B Unknown
C 101475958 aasdh; beta-alanine-activating enzyme K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-]
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AAcyl-AMP ligase
B Fatty acyl-AMP ligase (FAAL)
B Aryl-AMP ligase
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APhospholipid acyltransferase
B GPAT
C 101480029 gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 101483931 gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
C 101465064 agpat9l; glycerol-3-phosphate acyltransferase 3-like K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
C 101472673 gpat3; glycerol-3-phosphate acyltransferase 3 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
C 101475977 gpat4; glycerol-3-phosphate acyltransferase 4 isoform X1 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
C 101485036 glycerol-3-phosphate acyltransferase 4 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
B LPAAT/LPLAT
C 101480285 agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
C 101468819 abhd5a; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
C 101483082 abhd5b; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
C 101478345 lclat1; lysocardiolipin acyltransferase 1 K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
C 101470474 tafazzin; tafazzin K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
C 101467566 mboat2b; lysophospholipid acyltransferase 2b K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 101470756 mboat2a; membrane-bound glycerophospholipid O-acyltransferase 2 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 101477417 mboat1; lysophospholipid acyltransferase 1 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
C 101468489 agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 101486335 agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
C 101472375 lpcat2; lysophosphatidylcholine acyltransferase 2 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 101475100 lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 101478534 lpcat1; lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
C 101463770 lpcat4; lysophospholipid acyltransferase LPCAT4 K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
C 101487696 lysophospholipid acyltransferase LPCAT4-like K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
C 101484381 lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
C 101482416 lpcat3; lysophospholipid acyltransferase 5 K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
C 101478074 mboat7; membrane-bound acylglycerophosphatidylinositol O-acyltransferase mboat7 K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
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AOthers
B Multifunctional type
B Component type
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: March 16, 2026
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Desaturase/elongase family classification based on Hashimoto et al. (2008)