+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Necator americanus (New World hookworm)</h2>
%<!-- w=600, -->
!
A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        NECAME_06045 ribosomal RNA large subunit methyltransferase J	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
E        NECAME_12065 ribosomal RNA large subunit methyltransferase J	K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296] 
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        NECAME_09352 cleavage and polyadenylation specificity factor subunit 5 family protein	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
E        NECAME_13071 hypothetical protein	K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        NECAME_04034 Pre-mRNA cleavage complex II protein Clp1	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        NECAME_05647 hypothetical protein	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        NECAME_10049 RNA-metabolizing metallo-beta-lactamase	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        NECAME_03983 metallo-beta-lactamase domain protein	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        NECAME_09006 zinc knuckle	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        NECAME_10867 hypothetical protein	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        NECAME_06802 hypothetical protein	K15542 PFS2; polyadenylation factor subunit 2 
E        NECAME_05534 WD domain, G-beta repeat protein	K14962 WDR82; COMPASS component SWD2 
E        NECAME_08547 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_09449 hypothetical protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_05538 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_04745 phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_13795 putative phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_00340 hypothetical protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_14064 putative phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_13571 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_12025 putative phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_06613 phosphoprotein phosphatase 1 family protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_08144 putative phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_04482 phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_04327 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_13709 phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_09560 phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_02273 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_06677 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_10540 phosphoprotein phosphatase 1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_13169 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_13139 phosphoprotein phosphatase 1 domain protein	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NECAME_14371 Ssu72-like protein	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        NECAME_10433 WD domain, G-beta repeat protein	K14406 CSTF1; cleavage stimulation factor subunit 1 
E        NECAME_07552 hypothetical protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        NECAME_10435 suppressor of forked protein	K14408 CSTF3; cleavage stimulation factor subunit 3 
D      U7-dependent histone pre-mRNA processing factors
E        NECAME_13381 LSM domain protein	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        NECAME_13929 LSM domain protein	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        NECAME_15825 LSM domain protein	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        NECAME_06624 LSM domain protein	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        NECAME_15393 LSM domain protein	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        NECAME_10049 RNA-metabolizing metallo-beta-lactamase	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        NECAME_03983 metallo-beta-lactamase domain protein	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        NECAME_07552 hypothetical protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
E        NECAME_05759 MT-A70 protein	K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72] 
E        NECAME_02035 hypothetical protein	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
E        NECAME_12626 hypothetical protein	K13190 RBM15; RNA-binding protein 15 
D      Poly(A) addition factors
E        NECAME_06578 Poly(A) polymerase central domain protein	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        NECAME_03054 hypothetical protein	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        NECAME_09259 hypothetical protein	K13192 RBM26; RNA-binding protein 26 
E        NECAME_11923 hypothetical protein	K23600 TARDBP; TAR DNA-binding protein 43 
C    Other processing factors
D      NECAME_09573 hypothetical protein	K13102 KIN; DNA/RNA-binding protein KIN17 
D      NECAME_07248 hypothetical protein	K23038 ZC3H14; zinc finger CCCH domain-containing protein 14 
D      NECAME_00896 hypothetical protein	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        NECAME_00814 mago nashi protein	K12877 MAGOH; protein mago nashi 
E        NECAME_12528 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NECAME_09094 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NECAME_07406 spliceosome RNA helicase BAT1	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        NECAME_08236 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NECAME_11629 helicase protein	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NECAME_00786 CASC3/Barentsz eIF4AIII binding protein	K14323 CASC3; protein CASC3 
E        NECAME_04033 Sin3 associated polypeptide p18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        NECAME_01311 SAP domain protein	K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus 
E        NECAME_17422 RNA-binding protein with serine-rich domain 1 family protein	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        NECAME_08561 PWI domain protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        NECAME_08287 WD domain, G-beta repeat protein	K12878 THOC1; THO complex subunit 1 
E        NECAME_15946 WD domain, G-beta repeat protein	K12880 THOC3; THO complex subunit 3 
E        NECAME_12528 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NECAME_09094 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NECAME_12713 hypothetical protein	K13174 THOC5; THO complex subunit 5 
E        NECAME_04887 WD domain, G-beta repeat protein	K13175 THOC6; THO complex subunit 6 
E        NECAME_12393 Tho complex subunit 7	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        NECAME_01345 PCI domain protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        NECAME_09564 DSS1/SEM1 family protein	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        NECAME_12639 SAC3/GANP family protein	K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48] 
D      Nuclear pore complex
E        NECAME_08960 hypothetical protein	K09291 TPR; nucleoprotein TPR 
E        NECAME_00991 putative nucleoporin GLE2	K14298 RAE1; mRNA export factor 
E        NECAME_14125 WD domain, G-beta repeat protein	K14004 SEC13; protein transport protein SEC13 
E        NECAME_08289 hypothetical protein	K14304 NUP85; nuclear pore complex protein Nup85 
E        NECAME_16528 hypothetical protein	K14308 NUP54; nuclear pore complex protein Nup54 
E        NECAME_16688 Nsp1-like region	K14306 NUP62; nuclear pore complex protein Nup62 
E        NECAME_09712 hypothetical protein	K14309 NUP93; nuclear pore complex protein Nup93 
E        NECAME_00901 hypothetical protein	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        NECAME_15222 hypothetical protein	K14301 NUP107; nuclear pore complex protein Nup107 
E        NECAME_14531 Zn-finger in Ran binding protein	K14296 NUP153; nuclear pore complex protein Nup153 
E        NECAME_07506 hypothetical protein	K14312 NUP155; nuclear pore complex protein Nup155 
E        NECAME_07503 hypothetical protein	K14312 NUP155; nuclear pore complex protein Nup155 
E        NECAME_09011 hypothetical protein	K14313 NUP35; nuclear pore complex protein Nup53 
E        NECAME_17598 hypothetical protein	K14310 NUP205; nuclear pore complex protein Nup205 
E        NECAME_13989 hypothetical protein	K14314 NUP210; nuclear pore complex protein Nup210 
E        NECAME_15714 hypothetical protein	K14317 NUP214; nuclear pore complex protein Nup214 
E        NECAME_15581 nucleoporin protein Ndc1-Nup	K14315 NDC1; nucleoporin NDC1 
E        NECAME_15577 WD domain, G-beta repeat protein	K14299 SEH1; nucleoporin SEH1 
E        NECAME_06721 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        NECAME_00301 nuclear transport factor 2 domain protein	K14285 NXT1_2; NTF2-related export protein 1/2 
D      Ran-mediated transport factors
E        NECAME_03527 Ras family protein	K07936 RAN; GTP-binding nuclear protein Ran 
E        NECAME_10284 ELAV/HuD family splicing factor	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        NECAME_02265 hypothetical protein	K18726 FAF2; FAS-associated factor 2 
E        NECAME_04155 transitional endoplasmic reticulum ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        NECAME_07516 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        NECAME_00345 Importin-beta protein	K14290 XPO1; exportin-1 
E        NECAME_10134 hypothetical protein	K18460 XPO7; exportin-7 
E        NECAME_08935 hypothetical protein	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        NECAME_15855 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_14736 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_13343 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_05500 helicase protein	K03257 EIF4A; translation initiation factor 4A 
E        NECAME_12849 DEAD/DEAH box helicase	K03257 EIF4A; translation initiation factor 4A 
E        NECAME_15906 hypothetical protein	K03258 EIF4B; translation initiation factor 4B 
E        NECAME_15881 endonuclease/exonuclease/phosphatase family protein	K18729 ANGEL; protein angel 
E        NECAME_09277 KH domain protein	K15516 FMR; fragile X mental retardation protein 
E        NECAME_16147 cytoplasmic Fragile-X interacting family protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        NECAME_02784 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_08726 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_03791 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_07711 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_03386 ATP-dependent RNA helicase DDX3X family protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NECAME_12751 GYF domain protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        NECAME_05732 polyadenylate binding protein	K13126 PABPC; polyadenylate-binding protein 
E        NECAME_16535 hypothetical protein	K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
E        NECAME_09423 hypothetical protein	K07575 MCTS; malignant T-cell-amplified sequence 
E        NECAME_00912 density-regulated protein DRP1	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        NECAME_11196 mago binding protein	K14294 WIBG; partner of Y14 and mago 
E        NECAME_09225 hypothetical protein	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        NECAME_02563 hypothetical protein	K14411 MSI; RNA-binding protein Musashi 
E        NECAME_04435 hypothetical protein	K14411 MSI; RNA-binding protein Musashi 
E        NECAME_00784 elongation factor 1-alpha domain protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        NECAME_10615 putative translation factor pelota	K06965 PELO; protein pelota 
E        NECAME_04809 hypothetical protein	K14396 PABPN1; polyadenylate-binding protein 2 
E        NECAME_11844 helicase protein	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        NECAME_03782 HAT repeat protein	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        NECAME_11019 hypothetical protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        NECAME_16979 regulator of condensation family protein	K11493 RCC1; regulator of chromosome condensation 
C    Surveillance factors
D      Surveillance complex
E        NECAME_03717 peptide chain release factor eRF/aRF, subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        NECAME_09968 putative elongation factor 1-alpha	K03267 ERF3; peptide chain release factor subunit 3 
E        NECAME_12221 MIF4G domain protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        NECAME_10802 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        NECAME_07445 Ser/Thr phosphatase family protein	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        NECAME_05691 HEAT repeat protein	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        NECAME_00199 HEAT repeat protein	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        NECAME_06065 WD domain, G-beta repeat protein	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        NECAME_01899 hypothetical protein	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        NECAME_13872 protein phosphatase 2A regulatory B subunit	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        NECAME_08546 protein phosphatase 2A regulatory B subunit	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        NECAME_11161 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        NECAME_11206 hypothetical protein	K18735 SMG9; protein SMG9 
E        NECAME_12751 GYF domain protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        NECAME_07617 helicase protein	K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6] 
E        NECAME_08269 elongation factor Tu GTP binding domain protein	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        NECAME_16031 CPL domain protein	K14844 PUF6; pumilio homology domain family member 6 
E        NECAME_06047 hypothetical protein	K18739 BICD; protein bicaudal D 
E        NECAME_13158 3'-5' exonuclease	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
E        NECAME_04082 Actin	K05692 ACTB_G1; actin beta/gamma 1 
E        NECAME_03869 Actin	K05692 ACTB_G1; actin beta/gamma 1 
E        NECAME_10426 nanos RNA binding domain protein	K18741 NANOS1; protein nanos 1 
D      Trans-acting binding proteins
E        NECAME_05682 KH domain protein	K13210 FUBP; far upstream element-binding protein 
E        NECAME_12519 translation elongation factor EF-1, subunit alpha	K03231 EEF1A; elongation factor 1-alpha 
E        NECAME_04258 translation elongation factor EF-1, subunit alpha	K03231 EEF1A; elongation factor 1-alpha 
E        NECAME_09624 putative GTP-ase activating protein	K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1 
E        NECAME_04517 hypothetical protein	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        NECAME_08208 hnRNP-L/PTB/hephaestus splicing factor family protein	K13218 PTBP1; polypyrimidine tract-binding protein 1 
E        NECAME_00456 hypothetical protein	K03102 SQD; squid 
E        NECAME_02784 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_08726 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_03791 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_07711 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
D      Other mRNA localization factors
E        NECAME_09277 KH domain protein	K15516 FMR; fragile X mental retardation protein 
E        NECAME_16147 cytoplasmic Fragile-X interacting family protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        NECAME_08819 cold-shock DNA-binding domain protein	K09276 YBX1; Y-box-binding protein 1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        NECAME_06654 XRN 5'-3' exonuclease	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        NECAME_00512 piwi domain protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        NECAME_00996 PAZ domain protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        NECAME_17223 piwi domain protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        NECAME_15855 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_14736 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_13343 eukaryotic initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NECAME_03386 ATP-dependent RNA helicase DDX3X family protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NECAME_16824 DEAD/DEAH box helicase	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        NECAME_10438 KH domain protein	K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
E        NECAME_01429 FFD and TFG box motif protein	K18749 LSM14; protein LSM14 
E        NECAME_08819 cold-shock DNA-binding domain protein	K09276 YBX1; Y-box-binding protein 1 
E        NECAME_05145 LIM domain protein	K16682 AJUBA; LIM domain-containing protein 
E        NECAME_06796 HEAT repeat protein	K18752 TNPO1; transportin-1 
E        NECAME_11161 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        NECAME_09897 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        NECAME_08575 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        NECAME_04918 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        NECAME_11887 cold-shock DNA-binding domain protein	K18754 LIN28; protein lin-28 
E        NECAME_02360 hypothetical protein	K18756 BICC1; protein bicaudal C 
E        NECAME_09225 hypothetical protein	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        NECAME_14910 kinase domain protein	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        NECAME_17311 SH2 domain protein	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        NECAME_10204 la domain protein	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        NECAME_05544 hydrolase, NUDIX family	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        NECAME_09832 Dcp1-like decapping family protein	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        NECAME_02150 LSM domain protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        NECAME_07185 LSM domain protein	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        NECAME_02103 LSM domain protein	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        NECAME_04760 LSM domain protein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        NECAME_00222 LSM domain protein	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        NECAME_16974 LSM domain protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        NECAME_00455 LSM domain protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        NECAME_00454 hypothetical protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        NECAME_08085 tetratricopeptide repeat protein	K10407 KLC; kinesin light chain 
E        NECAME_10757 Tubulin/FtsZ family, GTPase domain protein	K07374 TUBA; tubulin alpha 
E        NECAME_14945 Tubulin/FtsZ family, GTPase domain protein	K07374 TUBA; tubulin alpha 
E        NECAME_02877 Tubulin/FtsZ family, GTPase domain protein	K07374 TUBA; tubulin alpha 
E        NECAME_01430 tubulin/FtsZ family protein	K07374 TUBA; tubulin alpha 
E        NECAME_10307 tubulin/FtsZ family protein	K07374 TUBA; tubulin alpha 
E        NECAME_11785 Tubulin/FtsZ family, GTPase domain protein	K07374 TUBA; tubulin alpha 
E        NECAME_07876 Tubulin/FtsZ family, GTPase domain protein	K07374 TUBA; tubulin alpha 
E        NECAME_02784 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_08726 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_03791 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_07711 hypothetical protein	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        NECAME_15083 CCR4-Not complex component, Not1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        NECAME_10640 NOT2 / NOT3 / NOT5 family protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        NECAME_08440 Not1 domain, CCR4-Not complex component	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        NECAME_15392 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        NECAME_13634 leucine Rich repeat-containing domain protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        NECAME_12742 CAF1 family ribonuclease	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        NECAME_14808 RNB-like protein	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        NECAME_12022 hypothetical protein	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        NECAME_12518 hypothetical protein	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        NECAME_12221 MIF4G domain protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        NECAME_10802 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
E        NECAME_01620 NHL repeat protein	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        NECAME_06087 RNA polymerase Rpb7 protein	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
D      Stress granule specific factors
E        NECAME_08795 hypothetical protein	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        NECAME_14518 hypothetical protein	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        NECAME_05732 polyadenylate binding protein	K13126 PABPC; polyadenylate-binding protein 
E        NECAME_04517 hypothetical protein	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        NECAME_09277 KH domain protein	K15516 FMR; fragile X mental retardation protein 
E        NECAME_03626 nuclear transport factor 2 domain protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        NECAME_04096 hypothetical protein	K03253 EIF3B; translation initiation factor 3 subunit B 
E        NECAME_05500 helicase protein	K03257 EIF4A; translation initiation factor 4A 
E        NECAME_12849 DEAD/DEAH box helicase	K03257 EIF4A; translation initiation factor 4A 
E        NECAME_08236 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NECAME_11629 helicase protein	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NECAME_15906 hypothetical protein	K03258 EIF4B; translation initiation factor 4B 
E        NECAME_06412 kinase domain protein	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        NECAME_06721 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        NECAME_05159 hypothetical protein	K18763 LARP4; la-related protein 4 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        NECAME_09832 Dcp1-like decapping family protein	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        NECAME_05544 hydrolase, NUDIX family	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        NECAME_16824 DEAD/DEAH box helicase	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
D      Lsm complex
E        NECAME_02150 LSM domain protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        NECAME_07185 LSM domain protein	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        NECAME_02103 LSM domain protein	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        NECAME_04760 LSM domain protein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        NECAME_00222 LSM domain protein	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        NECAME_16974 LSM domain protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        NECAME_00455 LSM domain protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        NECAME_00454 hypothetical protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        NECAME_06654 XRN 5'-3' exonuclease	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        NECAME_15462 scavenger mRNA decapping enzyme	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        NECAME_16357 RNA polymerase III subunit Rpc25	K07573 CSL4; exosome complex component CSL4 
E        NECAME_12659 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
E        NECAME_07177 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
E        NECAME_04311 3' exoribonuclease family, domain 1	K11600 RRP41; exosome complex component RRP41 
E        NECAME_04349 3' exoribonuclease family, domain 1	K12589 RRP42; exosome complex component RRP42 
E        NECAME_18242 hypothetical protein	K12586 RRP43; exosome complex component RRP43 
E        NECAME_12935 3' exoribonuclease family, domain 1	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        NECAME_06761 3'-5' exonuclease	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        NECAME_16415 hypothetical protein	K12592 C1D; exosome complex protein LRP1 
E        NECAME_12189 hypothetical protein	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
E        NECAME_01890 DEAD/DEAH box helicase	K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] 
D      TRAMP complex
E        NECAME_12666 nucleotidyltransferase domain protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        NECAME_06651 DSHCT domain protein	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        NECAME_06612 WD domain, G-beta repeat protein	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        NECAME_13634 leucine Rich repeat-containing domain protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        NECAME_15083 CCR4-Not complex component, Not1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        NECAME_10640 NOT2 / NOT3 / NOT5 family protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        NECAME_08440 Not1 domain, CCR4-Not complex component	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        NECAME_15392 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        NECAME_12742 CAF1 family ribonuclease	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        NECAME_09724 cell differentiation family, Rcd1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
D      Pan complex
E        NECAME_12518 hypothetical protein	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
D      Other 3'-5' decay factors
E        NECAME_18203 CAF1 family ribonuclease	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        NECAME_05305 exonuclease	K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-] 
E        NECAME_15462 scavenger mRNA decapping enzyme	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        NECAME_10694 hypothetical protein	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
C    Other degradation factors
D      RNases
E        NECAME_05272 hypothetical protein	K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-] 
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        NECAME_15253 RNase3 domain protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        NECAME_10285 oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        NECAME_09088 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        NECAME_09619 putative polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        NECAME_01086 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        NECAME_12361 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK 
E        NECAME_04064 chaperonin GroL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        NECAME_12659 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
E        NECAME_07177 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
E        NECAME_16357 RNA polymerase III subunit Rpc25	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        NECAME_04311 3' exoribonuclease family, domain 1	K11600 RRP41; exosome complex component RRP41 
E        NECAME_04349 3' exoribonuclease family, domain 1	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: April 25, 2024