+F Chromosome and associated proteins KO
#
Chromosome and Associated Proteins - Necator americanus (New World hookworm)
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
D NECAME_02318 RecF/RecN/SMC protein K06636 SMC1; structural maintenance of chromosome 1
D NECAME_08361 Rad21 / Rec8 like protein K06670 SCC1; cohesin complex subunit SCC1
D NECAME_03086 STAG domain protein K06671 STAG1_2; cohesin complex subunit SA-1/2
C Adherin complex
D NECAME_05772 HEAT repeat protein K06672 SCC2; cohesin loading factor subunit SCC2
D NECAME_03432 hypothetical protein K11266 MAU2; MAternally affected uncoordination
D NECAME_13460 HEAT repeat protein K11267 PDS5; sister chromatid cohesion protein PDS5
D NECAME_16462 hypothetical protein K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
C CTF18-RFC complex
D NECAME_08230 Ctf8 K11270 CTF8; chromosome transmission fidelity protein 8
D NECAME_01515 hypothetical protein K11271 DSCC1; sister chromatid cohesion protein DCC1
D NECAME_04463 replication factor K10755 RFC2_4; replication factor C subunit 2/4
D NECAME_07567 replication factor C subunit 3 family protein K10756 RFC3_5; replication factor C subunit 3/5
D NECAME_12475 putative replication factor C small subunit K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
D NECAME_11109 timeless protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D NECAME_00236 replication Fork Protection Component Swi3 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Other sister chromatid cohesion factors
D NECAME_00853 DEAD2 domain protein K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D NECAME_14130 acetyltransferase, GNAT family K20791 NAA10_11; N-alpha-acetyltransferase 10/11 [EC:2.3.1.255]
D NECAME_03498 tetratricopeptide repeat protein K20792 NAA15_16; N-alpha-acetyltransferase 15/16, NatA auxiliary subunit
D NECAME_10330 acetyltransferase, GNAT family K20793 NAA50; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
D NECAME_02318 RecF/RecN/SMC protein K06636 SMC1; structural maintenance of chromosome 1
D NECAME_06966 wings apart-like protein K25163 WAPL; wings apart-like protein
C Synaptonemal complex
C DSB formation-related proteins
D NECAME_14254 SET domain protein K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
D NECAME_03630 type IIB DNA topoisomerase K10878 SPO11; meiotic recombination protein SPO11
C Others
D NECAME_07240 meiotic recombinase Dmc1 K10872 DMC1; meiotic recombination protein DMC1
D NECAME_07971 MutS domain V protein K08740 MSH4; DNA mismatch repair protein MSH4
B Nucleosome assembly factors
C Histones
D NECAME_07904 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_03554 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_15846 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_09380 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_01859 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_09198 linker histone H1 and H5 family protein K11275 H1_5; histone H1/5
D NECAME_14960 core histone H2A/H2B/H3/H4 K11251 H2A; histone H2A
D NECAME_09930 core histone H2A/H2B/H3/H4 K11251 H2A; histone H2A
D NECAME_00153 core histone H2A/H2B/H3/H4 K11251 H2A; histone H2A
D NECAME_06968 core histone H2A/H2B/H3/H4 K11251 H2A; histone H2A
D NECAME_18881 core histone H2A/H2B/H3/H4 K11251 H2A; histone H2A
D NECAME_03997 hypothetical protein K11252 H2B; histone H2B
D NECAME_09931 core histone H2A/H2B/H3/H4 K11252 H2B; histone H2B
D NECAME_00149 core histone H2A/H2B/H3/H4 K11252 H2B; histone H2B
D NECAME_00151 core histone H2A/H2B/H3/H4 K11252 H2B; histone H2B
D NECAME_00152 core histone H2A/H2B/H3/H4 K11252 H2B; histone H2B
D NECAME_10884 hypothetical protein K11252 H2B; histone H2B
D NECAME_18620 core histone H2A/H2B/H3/H4 K11252 H2B; histone H2B
D NECAME_08585 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_10885 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_19488 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_10421 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_03059 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_12595 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_16785 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_09673 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_16786 core histone H2A/H2B/H3/H4 K11253 H3; histone H3
D NECAME_00803 core histone H2A/H2B/H3/H4 K11254 H4; histone H4
D NECAME_09932 core histone H2A/H2B/H3/H4 K11254 H4; histone H4
D NECAME_08586 core histone H2A/H2B/H3/H4 K11254 H4; histone H4
D NECAME_16750 histone H4-1 family protein K11254 H4; histone H4
D NECAME_16752 core histone H2A/H2B/H3/H4 K11254 H4; histone H4
D NECAME_16784 core histone H2A/H2B/H3/H4 K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
E NECAME_02061 hypothetical protein K11279 NAP1L1; nucleosome assembly protein 1-like 1
E NECAME_07927 nucleosome assembly protein K11290 SET; template-activating factor I
D CAF-1
E NECAME_05830 hypothetical protein K10750 CHAF1A; chromatin assembly factor 1 subunit A
E NECAME_00210 WD domain, G-beta repeat protein K10751 CHAF1B; chromatin assembly factor 1 subunit B
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D FACT complex
E NECAME_16525 structure-specific recognition protein K09272 SSRP1; FACT complex subunit SSRP1/POB3
E NECAME_15193 peptidase, M24 family K25639 SUPT16H; FACT complex subunit SPT16
D Other Histone chaperones and regulators
E NECAME_11398 tetratricopeptide repeat protein K11291 NASP; nuclear autoantigenic sperm protein
E NECAME_02873 S1 RNA binding domain protein K11292 SUPT6H; transcription elongation factor SPT6
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
D NECAME_00852 hypothetical protein K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
D NECAME_07741 Bromodomain protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D NECAME_03354 hypothetical protein K23358 TAF1; transcription initiation factor TFIID subunit 1, fungi type [EC:2.3.1.48]
D NECAME_05221 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D NECAME_13873 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D NECAME_07541 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D NECAME_17529 zinc finger, C2H2 type K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D NECAME_12639 SAC3/GANP family protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D NECAME_00363 acetyltransferase, GNAT family K20794 NAA40; N-alpha-acetyltransferase 40 [EC:2.3.1.257]
D NECAME_10635 acetyltransferase, GNAT family K21121 NAA60; N-alpha-acetyltransferase 60 [EC:2.3.1.259]
D NECAME_01460 acetyltransferase, GNAT family K21121 NAA60; N-alpha-acetyltransferase 60 [EC:2.3.1.259]
C HAT complexes
D PCAF complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_16950 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_14339 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_10158 transcription initiation factor IID, subunit K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E NECAME_13255 transcription initiation factor TFIID subunit A K03126 TAF12; transcription initiation factor TFIID subunit 12
D STAGA complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_02855 hypothetical protein K15127 TADA2B; transcriptional adapter 2-beta
E NECAME_16950 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_14339 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_10158 transcription initiation factor IID, subunit K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E NECAME_13255 transcription initiation factor TFIID subunit A K03126 TAF12; transcription initiation factor TFIID subunit 12
E NECAME_09923 splicing factor 3B subunit 3 family protein K12830 SF3B3; splicing factor 3B subunit 3
D TFTC complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_02855 hypothetical protein K15127 TADA2B; transcriptional adapter 2-beta
E NECAME_02609 hypothetical protein K03128 TAF2; transcription initiation factor TFIID subunit 2
E NECAME_08468 hypothetical protein K03129 TAF4; transcription initiation factor TFIID subunit 4
E NECAME_16950 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_14339 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_16529 TAFII55 protein conserved region K03132 TAF7; transcription initiation factor TFIID subunit 7
E NECAME_10158 transcription initiation factor IID, subunit K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E NECAME_13255 transcription initiation factor TFIID subunit A K03126 TAF12; transcription initiation factor TFIID subunit 12
E NECAME_09923 splicing factor 3B subunit 3 family protein K12830 SF3B3; splicing factor 3B subunit 3
D TIP60 complex
E NECAME_05221 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E NECAME_15633 hypothetical protein K11322 EPC; enhancer of polycomb-like protein
E NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
E NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
E NECAME_00425 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
E NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
E NECAME_05329 YEATS family protein K11341 YEATS4; YEATS domain-containing protein 4
E NECAME_15094 histone acetyltransferase subunit NuA4 K11344 MEAF6; chromatin modification-related protein EAF6
D HBO1 complex
E NECAME_17529 zinc finger, C2H2 type K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
E NECAME_15094 histone acetyltransferase subunit NuA4 K11344 MEAF6; chromatin modification-related protein EAF6
D MOZ/MORF complex
E NECAME_15094 histone acetyltransferase subunit NuA4 K11344 MEAF6; chromatin modification-related protein EAF6
D SAGA complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_17214 hypothetical protein K11363 SGF11; SAGA-associated factor 11
E NECAME_05083 hypothetical protein K11364 SGF29; SAGA-associated factor 29
E NECAME_16950 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_14339 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_10158 transcription initiation factor IID, subunit K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E NECAME_13255 transcription initiation factor TFIID subunit A K03126 TAF12; transcription initiation factor TFIID subunit 12
E NECAME_11560 protein, SNF2 family K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
D SLIK complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_17214 hypothetical protein K11363 SGF11; SAGA-associated factor 11
E NECAME_05083 hypothetical protein K11364 SGF29; SAGA-associated factor 29
E NECAME_16950 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_14339 hypothetical protein K03131 TAF6; transcription initiation factor TFIID subunit 6
E NECAME_10158 transcription initiation factor IID, subunit K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E NECAME_13255 transcription initiation factor TFIID subunit A K03126 TAF12; transcription initiation factor TFIID subunit 12
E NECAME_11560 protein, SNF2 family K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
D ADA-HAT complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_05083 hypothetical protein K11364 SGF29; SAGA-associated factor 29
D HAT-A2 complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
D ATAC complex
E NECAME_06563 PCAF protein K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E NECAME_05083 hypothetical protein K11364 SGF29; SAGA-associated factor 29
E NECAME_10390 hypothetical protein K21751 DR1; down-regulator of transcription 1
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D HATB complex
E NECAME_00852 hypothetical protein K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D NSL complex
E NECAME_13873 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E NECAME_07541 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E NECAME_11337 tetratricopeptide repeat protein K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E NECAME_05535 kelch repeat protein K14966 HCFC1; host cell factor 1
D MSL complex
E NECAME_13873 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
E NECAME_07541 MOZ/SAS family protein K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D NuA3 complex
D NuA4 complex
E NECAME_05221 MOZ/SAS family protein K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E NECAME_05329 YEATS family protein K11341 YEATS4; YEATS domain-containing protein 4
E NECAME_00425 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E NECAME_15094 histone acetyltransferase subunit NuA4 K11344 MEAF6; chromatin modification-related protein EAF6
E NECAME_15633 hypothetical protein K11322 EPC; enhancer of polycomb-like protein
E NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
E NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_15010 histone deacetylase family protein K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
D Class II HDACs
E NECAME_12111 histone deacetylase family protein K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
E NECAME_02337 transcriptional regulator, Sir2 family K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
E NECAME_12546 transcriptional regulator, Sir2 family K11412 SIRT2; NAD-dependent protein deacetylase sirtuin 2 [EC:2.3.1.286]
E NECAME_11356 transcriptional regulator, Sir2 family K11414 SIRT4; NAD-dependent protein deacetylase/lipoamidase sirtuin 4 [EC:2.3.1.286 2.3.1.313]
E NECAME_12226 transcriptional regulator, Sir2 family K11416 SIRT6; NAD-dependent protein deacetylase sirtuin 6 [EC:2.3.1.286]
D Class IV HDACs
E NECAME_02250 histone deacetylase family protein K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
C HDAC complexes
D Sin3A-HDAC complex
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
E NECAME_03206 hypothetical protein K19201 SUDS3; Sin3 histone deacetylase corepressor complex component SDS3
E NECAME_04033 Sin3 associated polypeptide p18 K14324 SAP18; histone deacetylase complex subunit SAP18
E NECAME_01264 ARID/BRIGHT DNA binding domain protein K19195 ARID4B; AT-rich interactive domain-containing protein 4B
E NECAME_10126 hypothetical protein K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins
D BRAF-HDAC complex
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D REST complex
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_03625 hypothetical protein K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D SHIP complex
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D MiDAC complex
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SMART complex
E NECAME_15010 histone deacetylase family protein K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
E NECAME_01071 WD domain, G-beta repeat protein K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
E NECAME_10281 hypothetical protein K23398 TRIP4; activating signal cointegrator 1
E NECAME_01050 HMG box K24660 HMG20A; high mobility group protein 20A
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E NECAME_11271 histone methylation protein DOT1 K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
E NECAME_02467 SET domain protein K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E NECAME_14254 SET domain protein K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
E NECAME_11499 hypothetical protein K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
E NECAME_10199 SET domain protein K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
E NECAME_11052 transposase K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E NECAME_07501 SET domain protein K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E NECAME_11050 hypothetical protein K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E NECAME_11055 hypothetical protein K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
E NECAME_05130 SET domain protein K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
E NECAME_06579 hypothetical protein K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
E NECAME_12013 SET domain protein K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
D PRMTs (protein arginine metyltransferases)
E NECAME_12957 methyltransferase domain protein K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E NECAME_10236 Skb1 methyltransferase K02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]
C HMT complexes
D COMPASS/SET1 complex
E NECAME_12487 WD domain, G-beta repeat protein K14961 RBBP5; COMPASS component SWD1
E NECAME_05534 WD domain, G-beta repeat protein K14962 WDR82; COMPASS component SWD2
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E NECAME_12217 hypothetical protein K14965 DPY30; protein dpy-30
E NECAME_05535 kelch repeat protein K14966 HCFC1; host cell factor 1
D COMPASS/SET1 complex (yeast)
E NECAME_12487 WD domain, G-beta repeat protein K14961 RBBP5; COMPASS component SWD1
E NECAME_05534 WD domain, G-beta repeat protein K14962 WDR82; COMPASS component SWD2
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
D MLL-HCF complex
E NECAME_12217 hypothetical protein K14965 DPY30; protein dpy-30
E NECAME_12487 WD domain, G-beta repeat protein K14961 RBBP5; COMPASS component SWD1
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E NECAME_05535 kelch repeat protein K14966 HCFC1; host cell factor 1
D MLL3/MLL4 complex
E NECAME_02467 SET domain protein K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
E NECAME_12217 hypothetical protein K14965 DPY30; protein dpy-30
E NECAME_12487 WD domain, G-beta repeat protein K14961 RBBP5; COMPASS component SWD1
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E NECAME_18085 hypothetical protein K14972 PAXIP1; PAX-interacting protein 1
E NECAME_16581 BRCA1 protein K14972 PAXIP1; PAX-interacting protein 1
D Dot1-containing complex
E NECAME_11271 histone methylation protein DOT1 K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
C Histone demethylases
D NECAME_12085 amine oxidase K19413 KDM1B; lysine-specific histone demethylase 1B [EC:1.-.-.-]
D NECAME_11545 hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
D NECAME_07929 hypothetical protein K22610 RSBN1; lysine-specific demethylase 9 [EC:1.14.11.-]
D NECAME_07829 JmjC domain protein K19415 PHF8; [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65 1.14.11.-]
D NECAME_11131 hypothetical protein K16914 RIOX1; protein-L-histidine (3S)-3-hydroxylase / [histone H3]-trimethyl-L-lysine4/36 demethylase [EC:1.14.11.79 1.14.11.67 1.14.11.69]
D NECAME_13098 JmjC domain protein K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
D NECAME_12380 JmjC domain protein K11323 JMJD6; histone arginine demethylase JMJD6 [EC:1.14.11.-]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E NECAME_01579 zinc finger, C3HC4 type K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E PRC1.4 specific proteins
F NECAME_11584 mbt repeat protein K11465 SCML2; sex comb on midleg-like protein 2
D Noncanonical PRC1 (PRC1.1)
E NECAME_01579 zinc finger, C3HC4 type K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E NECAME_11368 Zn-finger in Ran binding protein K11468 YAF2; YY1-associated factor 2
E NECAME_11545 hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E NECAME_14768 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
E NECAME_07064 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E NECAME_01579 zinc finger, C3HC4 type K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E NECAME_11368 Zn-finger in Ran binding protein K11468 YAF2; YY1-associated factor 2
E NECAME_06263 casein kinase II regulatory subunit K03115 CSNK2B; casein kinase II subunit beta
E NECAME_10429 casein kinase II regulatory subunit K03115 CSNK2B; casein kinase II subunit beta
E NECAME_02008 WD domain, G-beta repeat protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
D Noncanonical PRC1 (PRC1.6)
E NECAME_01579 zinc finger, C3HC4 type K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
E NECAME_11368 Zn-finger in Ran binding protein K11468 YAF2; YY1-associated factor 2
E NECAME_05371 Helix-loop-helix DNA-binding domain protein K04453 MAX; Max protein
E NECAME_09430 WD domain, G-beta repeat protein K14963 WDR5; COMPASS component SWD3
E NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D PRC2.1
E NECAME_13657 WD domain, G-beta repeat protein K11462 EED; polycomb protein EED
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D PRC2.2
E NECAME_13657 WD domain, G-beta repeat protein K11462 EED; polycomb protein EED
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D PR-DUB complex
E NECAME_11337 tetratricopeptide repeat protein K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
E NECAME_05535 kelch repeat protein K14966 HCFC1; host cell factor 1
D Other PRC associated proteins
C Sir proteins
C Other histone modification proteins
D NECAME_10971 NNMT/PNMT/TEMT family protein K00541 NNMT; nicotinamide N-methyltransferase [EC:2.1.1.1]
D NECAME_10003 NNMT/PNMT/TEMT family protein K00541 NNMT; nicotinamide N-methyltransferase [EC:2.1.1.1]
D NECAME_01545 barrier to autointegration factor K21870 BANF; barrier-to-autointegration factor
D NECAME_02599 hypothetical protein K22611 SART3; squamous cell carcinoma antigen recognized by T-cells 3
D NECAME_10061 MYND finger K23218 ZMYND11; zinc finger MYND domain-containing protein 11
D NECAME_04635 prefoldin subunit K26537 UXT; protein UXT
B Chromosome condensation proteins
C Condensin I
D NECAME_02675 hypothetical protein K06677 YCS4; condensin complex subunit 1
C Condensin II
D NECAME_07569 hypothetical protein K11490 NCAPH2; condensin-2 complex subunit H2
C Other regulators of chromosome condensation
D NECAME_10714 DNA gyrase/topoisomerase IV, A subunit K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D NECAME_10365 DNA gyrase/topoisomerase IV, A subunit K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D NECAME_16979 regulator of condensation family protein K11493 RCC1; regulator of chromosome condensation
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
D CPC (chromosomal passenger complex)
E NECAME_18037 hypothetical protein K11515 INCENP; inner centromere protein
E NECAME_13182 kinase domain protein K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D KMN network proteins
E MIS12 complex
E NDC80 complex
F NECAME_02293 HEC/Ndc80p family protein K11547 NDC80; kinetochore protein NDC80
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
F NECAME_02293 HEC/Ndc80p family protein K11547 NDC80; kinetochore protein NDC80
E MIND kinetochore complex
D MIS16-MIS18 complex
E NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D DASH complex
D CBF3 complex
E NECAME_14768 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
E NECAME_07064 Skp1 family, dimerization domain protein K03094 SKP1; S-phase kinase-associated protein 1
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
E NECAME_10276 hypothetical protein K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
E NECAME_12676 HORMA domain protein K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
E NECAME_12274 WD domain, G-beta repeat protein K02180 BUB3; cell cycle arrest protein BUB3
D Motor proteins
E RZZ complex
E Dynein complex
F NECAME_13515 WD domain, G-beta repeat protein K10415 DYNC1I; dynein cytoplasmic 1 intermediate chain
F NECAME_13893 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
E NECAME_02949 kinesin motor domain protein K10393 KIF2_24; kinesin family member 2/24
D Protein kinases
E NECAME_13182 kinase domain protein K11479 AURKB; aurora kinase B [EC:2.7.11.1]
E NECAME_10130 kinase domain protein K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
E NECAME_10005 kinase domain protein K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E NECAME_10006 Mitogen-activated protein kinase 1 family protein K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E NECAME_11948 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
E NECAME_09217 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D Others
E NECAME_14544 ATPase, AAA family K22399 TRIP13; pachytene checkpoint protein 2
E NECAME_09685 CS domain protein K25866 NUDC; nuclear migration protein NudC
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
E NECAME_07445 Ser/Thr phosphatase family protein K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E NECAME_05691 HEAT repeat protein K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E NECAME_00199 HEAT repeat protein K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E NECAME_06065 WD domain, G-beta repeat protein K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E NECAME_01899 hypothetical protein K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E NECAME_13872 protein phosphatase 2A regulatory B subunit K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E NECAME_08546 protein phosphatase 2A regulatory B subunit K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
D NECAME_11546 chromo shadow domain protein K11585 CBX1; chromobox protein 1
C MBPs (metylated DNA binding proteins)
D NECAME_06271 hypothetical protein K11590 MBD2; methyl-CpG-binding domain protein 2
C Other heterochromatin formation proteins
D NECAME_15827 protein, SNF2 family K10779 ATRX; transcriptional regulator ATRX
D NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D NECAME_13442 CHDCT2 domain protein K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D NECAME_05130 SET domain protein K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
D NECAME_06579 hypothetical protein K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
D NECAME_11555 zinc finger, C2H2 type K19871 SALL; sal-like protein
B Gene silencing
C RISC (RNA-induced silencing complex)
D NECAME_14273 double stranded RNA binding domain protein K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
D NECAME_00512 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
D NECAME_00996 PAZ domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
D NECAME_17223 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
D NECAME_04914 piwi domain protein K02156 AUB; aubergine
D NECAME_03386 ATP-dependent RNA helicase DDX3X family protein K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
D NECAME_05765 RNA methyltransferase, TrmH family K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D NECAME_05764 hypothetical protein K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
C piRNA pathway
D NECAME_04914 piwi domain protein K02156 AUB; aubergine
D NECAME_07216 DEAD/DEAH box helicase K13982 DDX4; probable ATP-dependent RNA helicase DDX4 [EC:5.6.2.7]
D NECAME_06654 XRN 5'-3' exonuclease K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D NECAME_16824 DEAD/DEAH box helicase K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
E NECAME_00512 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
E NECAME_00996 PAZ domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
E NECAME_17223 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
D RDRC (RNA-directed RNA polymerase complex)
D Other RNAi proteins
E NECAME_05305 exonuclease K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E NECAME_16781 exonuclease K18418 ERI3; ERI1 exoribonuclease 3 [EC:3.1.-.-]
C microRNA pathway
D Microprocessor complex
E NECAME_05922 hypothetical protein K18419 DCGR8; microprocessor complex subunit DGCR8
E NECAME_15253 RNase3 domain protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
E NECAME_14273 double stranded RNA binding domain protein K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
E NECAME_00512 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
E NECAME_00996 PAZ domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
E NECAME_17223 piwi domain protein K11593 ELF2C; eukaryotic translation initiation factor 2C
D Other miRNA pathway proteins
C Transposable elements
D NECAME_01802 THAP domain protein K23203 THAP1_3; THAP domain-containing protein 1/3
D NECAME_14883 shTK domain protein K23205 THAP4; THAP domain-containing protein 4
D NECAME_11048 hypothetical protein K23222 HARBI1; nuclease HARBI1 [EC:3.1.-.-]
B Centrosome formation proteins
C Centriole proteins
D NECAME_06513 hypothetical protein K16458 CEP104; centrosomal protein CEP104
D NECAME_12928 hypothetical protein K16472 HYLS1; hydrolethalus syndrome protein 1
D NECAME_11975 Poly(ADP-ribose) polymerase catalytic domain protein K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D NECAME_11660 Poly(ADP-ribose) polymerase catalytic domain protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D NECAME_10715 phospholipase A2 K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
D NECAME_10714 DNA gyrase/topoisomerase IV, A subunit K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D NECAME_10365 DNA gyrase/topoisomerase IV, A subunit K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C Pericentriolar materials (PCM)
D Centriolar satellite
E NECAME_05770 tetratricopeptide repeat protein K16531 BBS4; Bardet-Biedl syndrome 4 protein
E NECAME_04724 hypothetical protein K16536 HOOK3; protein HOOK3
E NECAME_05140 PB1 domain protein K06093 PARD6; partitioning defective protein 6
E NECAME_16067 PB1 domain protein K06093 PARD6; partitioning defective protein 6
D Other PCM proteins
E NECAME_06083 ornithine decarboxylase antizyme K16548 OAZ1; ornithine decarboxylase antizyme 1
C Cyclins
D NECAME_09687 cyclin domain protein K06627 CCNA; cyclin-A
D NECAME_02319 cyclin domain protein K21771 CCNB3; G2/mitotic-specific cyclin-B3
D NECAME_03461 cyclin domain protein K06626 CCNE; G1/S-specific cyclin-E1
C Kinases and associated factors
D NECAME_11871 kinase domain protein K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D NECAME_12986 kinase domain protein K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
D NECAME_14987 hypothetical protein K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
D NECAME_10523 kinase domain protein K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D NECAME_03830 hypothetical protein K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D NECAME_11795 ankyrin repeat protein K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
D NECAME_11948 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D NECAME_09217 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D NECAME_13476 kinase domain protein K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
D NECAME_14910 kinase domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D NECAME_17311 SH2 domain protein K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E NECAME_11605 tubulin gamma chain family protein K10389 TUBG; tubulin gamma
D Other tubulins
E NECAME_10757 Tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E NECAME_14945 Tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E NECAME_02877 Tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E NECAME_01430 tubulin/FtsZ family protein K07374 TUBA; tubulin alpha
E NECAME_10307 tubulin/FtsZ family protein K07374 TUBA; tubulin alpha
E NECAME_11785 Tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E NECAME_07876 Tubulin/FtsZ family, GTPase domain protein K07374 TUBA; tubulin alpha
E NECAME_11014 Tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E NECAME_01536 Tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E NECAME_01549 Tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
E NECAME_02778 Tubulin/FtsZ family, GTPase domain protein K07375 TUBB; tubulin beta
D Dynactin complex
E NECAME_10325 hypothetical protein K04648 DCTN1; dynactin 1
E NECAME_08106 dynactin p62 family protein K10426 DCTN4; dynactin 4
E NECAME_04813 bacterial transferase hexapeptide repeat protein K10427 DCTN5; dynactin 5
E NECAME_10509 bacterial transferase hexapeptide repeat protein K10428 DCTN6; dynactin 6
E NECAME_12014 Actin K16575 ACTR1; centractin
E NECAME_07301 Actin K16576 ACTR10; actin-related protein 10
D BRISC complex
D Microtubule-associated proteins
E NECAME_09140 CAP-Gly domain protein K10421 CLIP1; CAP-Gly domain-containing linker protein 1
E NECAME_04759 EB1 protein K10436 MAPRE; microtubule-associated protein, RP/EB family
E NECAME_06629 hypothetical protein K10436 MAPRE; microtubule-associated protein, RP/EB family
E NECAME_01566 hypothetical protein K19573 ATAT1; alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108]
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
E NECAME_14138 hypothetical protein K02183 CALM; calmodulin
E NECAME_09810 EF hand K02183 CALM; calmodulin
E NECAME_16658 EF hand K02183 CALM; calmodulin
E NECAME_12924 EF hand K02183 CALM; calmodulin
E NECAME_04141 EF hand K02183 CALM; calmodulin
E NECAME_07239 EF hand K02183 CALM; calmodulin
E NECAME_11941 EF hand K02183 CALM; calmodulin
E NECAME_00013 EF hand K02183 CALM; calmodulin
E NECAME_01644 hypothetical protein K16722 SPD2; spindle-defective protein 2
D Regulators of centriole replication
E NECAME_13380 GTP-binding protein YchF K19788 OLA1; obg-like ATPase 1
E NECAME_02805 WD domain, G-beta repeat protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E NECAME_13476 kinase domain protein K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
E NECAME_03527 Ras family protein K07936 RAN; GTP-binding nuclear protein Ran
E NECAME_00345 Importin-beta protein K14290 XPO1; exportin-1
D Other centrosome duplication proteins
E NECAME_04996 hypothetical protein K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
E NECAME_01386 CS domain protein K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
E NECAME_00396 HAT repeat protein K12869 CRN; crooked neck
E NECAME_00646 putative phage head-tail adaptor K10263 FBXW5; F-box and WD-40 domain protein 5
E NECAME_17924 Leishmanolysin K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E NECAME_00306 hypothetical protein K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E NECAME_12070 Leishmanolysin K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
E NECAME_15211 MCM2/3/5 family protein K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
E NECAME_02124 origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
E NECAME_03597 RhoGAP domain protein K16733 RACGAP1; Rac GTPase-activating protein 1
E NECAME_18999 SAC3/GANP family protein K16734 SAC3D1; SAC3 domain-containing protein 1
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Other centriole associated proteins
D NECAME_15515 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D NECAME_10023 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D NECAME_00452 hypothetical protein K16750 BLOC1S2; biogenesis of lysosome-related organelles complex 1 subunit 2
D NECAME_08964 Ras family protein K04393 CDC42; cell division control protein 42
D NECAME_10295 Ras family protein K04393 CDC42; cell division control protein 42
D NECAME_08367 PDZ/DHR/GLGF domain protein K12076 DLG1; disks large protein 1
D NECAME_09435 MCM2/3/5 family protein K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D NECAME_09868 MCM2/3/5 family protein K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D NECAME_04629 paired box' domain protein K15608 PAX2; paired box protein 2
D NECAME_14415 GDP/GTP exchange factor Sec2p K16779 RAB3IP; Rab-3A-interacting protein
D NECAME_08466 Ras family protein K07901 RAB8A; Ras-related protein Rab-8A
D NECAME_07694 WD domain, G-beta repeat protein K21763 MAPKBP1; mitogen-activated protein kinase binding protein 1
D NECAME_01260 ATPase, AAA family K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D NECAME_17181 hypothetical protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D NECAME_11871 kinase domain protein K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D NECAME_08284 HEAT repeat protein K16803 CKAP5; cytoskeleton-associated protein 5
D NECAME_03673 tetratricopeptide repeat protein K15837 GPSM2; G-protein signaling modulator 2
D NECAME_02949 kinesin motor domain protein K10393 KIF2_24; kinesin family member 2/24
D NECAME_11898 kinesin motor domain protein K10405 KIFC1; kinesin family member C1
D NECAME_14200 Armadillo/beta-catenin-like repeat protein K15043 KPNA2_7; importin subunit alpha-1/8
D NECAME_19687 HEAT repeat protein K14293 KPNB1; importin subunit beta-1
D NECAME_08289 hypothetical protein K14304 NUP85; nuclear pore complex protein Nup85
D NECAME_00901 hypothetical protein K14297 NUP98; nuclear pore complex protein Nup98-Nup96
D NECAME_15222 hypothetical protein K14301 NUP107; nuclear pore complex protein Nup107
D NECAME_17598 hypothetical protein K14310 NUP205; nuclear pore complex protein Nup205
D NECAME_11619 hypothetical protein K20724 TMEM33; transmembrane protein 33
D NECAME_11288 Reticulon K20721 RTN1; reticulon-1
D NECAME_07722 WD domain, G-beta repeat protein K16794 PAFAH1B1; platelet-activating factor acetylhydrolase IB subunit alpha
D NECAME_00991 putative nucleoporin GLE2 K14298 RAE1; mRNA export factor
D NECAME_03527 Ras family protein K07936 RAN; GTP-binding nuclear protein Ran
D NECAME_13564 kinase domain protein K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
C APC/C complex
D NECAME_14005 cullin family protein K03349 APC2; anaphase-promoting complex subunit 2
D NECAME_06082 tetratricopeptide repeat protein K03350 APC3; anaphase-promoting complex subunit 3
D NECAME_15615 hypothetical protein K03352 APC5; anaphase-promoting complex subunit 5
D NECAME_10304 tetratricopeptide repeat protein K03353 APC6; anaphase-promoting complex subunit 6
D NECAME_15729 Anaphase-promoting complex, subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
D NECAME_09204 hypothetical protein K03358 APC11; anaphase-promoting complex subunit 11
C Aurora kinases
D NECAME_11871 kinase domain protein K11481 AURKA; aurora kinase A [EC:2.7.11.1]
D NECAME_13182 kinase domain protein K11479 AURKB; aurora kinase B [EC:2.7.11.1]
D Regulators of Aurora kinases
E NECAME_05145 LIM domain protein K16682 AJUBA; LIM domain-containing protein
E NECAME_04020 hypothetical protein K16831 BORA; protein aurora borealis
E NECAME_01663 hypothetical protein K16832 NEDD9; enhancer of filamentation 1
E NECAME_06743 protein phosphatase inhibitor 2 K16833 PPP1R2; protein phosphatase inhibitor 2
E NECAME_18530 P53 DNA-binding domain protein K04451 TP53; tumor protein p53
C TACC proteins
C Polo kinases
D NECAME_11948 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D NECAME_09217 kinase domain protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
D NECAME_13476 kinase domain protein K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
D NECAME_03625 hypothetical protein K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D NECAME_06329 hypothetical protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D NECAME_05461 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D NECAME_05646 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D NECAME_16117 HMG box K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_06394 Actin K11652 ACTL6B; actin-like protein 6B
D NECAME_08444 hypothetical protein K25605 BCL7; B-cell CLL/lymphoma 7 protein
D NECAME_01002 ARID/BRIGHT DNA binding domain protein K11653 ARID1; AT-rich interactive domain-containing protein 1
D NECAME_00668 hypothetical protein K13196 DPF2; zinc finger protein ubi-d4
C PBAF complex
D NECAME_03625 hypothetical protein K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D NECAME_06329 hypothetical protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D NECAME_05461 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D NECAME_05646 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D NECAME_16117 HMG box K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
D NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_06394 Actin K11652 ACTL6B; actin-like protein 6B
D NECAME_08444 hypothetical protein K25605 BCL7; B-cell CLL/lymphoma 7 protein
D NECAME_07223 Bromodomain protein K11723 BRD7; bromodomain-containing protein 7
D NECAME_07266 hypothetical protein K22197 BAF45A; BRG1-associated factor 45A
C GBAF(ncBAF) complex
D NECAME_03625 hypothetical protein K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
D NECAME_05461 SWIRM domain protein K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D NECAME_05646 SWIB/MDM2 domain protein K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
D NECAME_06394 Actin K11652 ACTL6B; actin-like protein 6B
D NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_08444 hypothetical protein K25605 BCL7; B-cell CLL/lymphoma 7 protein
C CHRAC complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D NECAME_11010 hypothetical protein K11655 BAZ1A; bromodomain adjacent to zinc finger domain protein 1A
D NECAME_06577 hypothetical protein K11656 CHRAC1; chromatin accessibility complex protein 1
D NECAME_09418 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D NECAME_15665 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C RSF complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C WICH complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C B-WICH complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D NECAME_08465 DEK protein K17046 DEK; protein DEK
D NECAME_01957 protein, SNF2 family K10841 ERCC6; DNA excision repair protein ERCC-6
D NECAME_00283 myosin head K10356 MYO1; myosin I
D NECAME_00856 hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D NECAME_10398 HEAT repeat protein K12828 SF3B1; splicing factor 3B subunit 1
C NORC complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C BRF complex
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
C NuRD complex
D NECAME_00813 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D NECAME_14453 histone deacetylase family protein K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D NECAME_13442 CHDCT2 domain protein K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
D NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D NECAME_11463 BAH domain protein K11660 MTA; metastasis-associated protein MTA
D NECAME_09289 hypothetical protein K23194 GATAD2; transcriptional repressor p66
D NECAME_09290 hypothetical protein K23194 GATAD2; transcriptional repressor p66
C NuRF complex
D NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex (fruit fly)
D NECAME_08522 protein, SNF2 family K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D NECAME_00807 WD domain, G-beta repeat protein K10752 RBBP4; histone-binding protein RBBP4
D NECAME_03650 inorganic diphosphatase K11726 NURF38; nucleosome-remodeling factor 38 kDa subunit [EC:3.6.1.1]
C CERF complex
C SRCAP complex
D NECAME_00865 prevent-host-death family protein K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D NECAME_11779 Actin K11662 ACTR6; actin-related protein 6
D NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D NECAME_05329 YEATS family protein K11341 YEATS4; YEATS domain-containing protein 4
D NECAME_00187 hypothetical protein K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D NECAME_04808 YL1 nuclear protein K11664 VPS72; vacuolar protein sorting-associated protein 72
C INO80 complex
D NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
C INO80 complex (yeast)
D NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
C RSC complex
C SWI/SNF complex
D NECAME_06329 hypothetical protein K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
C SWR1 complex
D NECAME_00865 prevent-host-death family protein K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D NECAME_04082 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_03869 Actin K05692 ACTB_G1; actin beta/gamma 1
D NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D NECAME_11779 Actin K11662 ACTR6; actin-related protein 6
D NECAME_05329 YEATS family protein K11341 YEATS4; YEATS domain-containing protein 4
D NECAME_00187 hypothetical protein K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D NECAME_04808 YL1 nuclear protein K11664 VPS72; vacuolar protein sorting-associated protein 72
C ASTRA complex
D NECAME_08748 TIP49 protein K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D NECAME_02959 TIP49 protein K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D NECAME_16465 hypothetical protein K11137 TELO2; telomere length regulation protein
C Other chromatin remodeling factors
D NECAME_01181 Bromodomain protein K08871 BRD2; bromodomain-containing protein 2
D NECAME_09173 protein, SNF2 family K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
D NECAME_02109 ankyrin repeat protein K21412 ANKLE2; ankyrin repeat and LEM domain-containing protein 2
D NECAME_10611 CW-type Zinc Finger K24135 MORC; MORC family CW-type zinc finger protein
D NECAME_10200 helicase protein K26273 SBNO; protein strawberry notch
#
AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
C HU (heat unstable protein)
C IHF (integration host factor)
C Other nucleoid associated proteins
B Chromosome partitioning proteins
C MukBEF complex
C Condensin-like complex
C Divisome proteins
C Inhibitors of FtsZ assembly
C Other chromosome partitioning proteins
D NECAME_16976 hypothetical protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 12, 2024