+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Neurospora crassa</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        NCU03971 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        NCU09778 cdc28; cdc28-like	K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] 
E        NCU03659 prk-3; protein kinase-3	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        NCU06260 mRNA-capping enzyme subunit alpha	K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] 
D      Cap binding complex
E        NCU04187 cap binding protein	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        NCU00210 nuclear cap binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        NCU09014 cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        NCU06314 hypothetical protein	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        NCU01696 mRNA cleavage factor complex component Pcf11	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        NCU02082 cft-1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        NCU06869 cleavage and polyadenylylation specificity factor	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        NCU03479 endoribonuclease ysh-1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        NCU08353 mRNA 3'-end-processing protein yth-1	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        NCU07654 pre-mRNA polyadenylation factor fip-1	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        NCU06718 zinc knuckle domain-containing protein	K15541 MPE1; protein MPE1 
E        NCU00037 polyadenylation factor subunit 2	K15542 PFS2; polyadenylation factor subunit 2 
E        NCU07885 WD repeat containing protein 82	K14962 WDR82; COMPASS component SWD2 
E        NCU00043 pph-3; protein phosphatase-3	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NCU07489 pzl-1; phosphatase-Z-like-1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        NCU03114 SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        NCU03311 polyadenylation factor subunit CstF64	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        NCU09435 mRNA 3'-end-processing protein RNA-14	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        NCU09128 hypothetical protein	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        NCU02508 hypothetical protein	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        NCU03625 small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        NCU06354 small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        NCU01614 hypothetical protein	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        NCU09880 small nuclear ribonucleoprotein SmG	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        NCU06869 cleavage and polyadenylylation specificity factor	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        NCU03479 endoribonuclease ysh-1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        NCU03311 polyadenylation factor subunit CstF64	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        NCU09128 hypothetical protein	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        NCU03838 transcription elongation factor spt-4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        NCU06929 transcription elongation factor spt-5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        NCU11362 DUF890 domain-containing protein	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        NCU08983 un-17; unknown-17	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
D      NCU03839 APF1	K13102 KIN; DNA/RNA-binding protein KIN17 
D      NCU02800 arsenite resistance protein Ars2	K27103 SRRT; serrate RNA effector molecule 
D      NCU16397 nuclear polyadenylated RNA-binding protein Nab2	K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        NCU03226 Y14 protein	K12876 RBM8A; RNA-binding protein 8A 
E        NCU04405 mago nashi protein	K12877 MAGOH; protein mago nashi 
E        NCU07421 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NCU01793 RNA binding domain-containing protein	K12881 THOC4; THO complex subunit 4 
E        NCU09076 ATP-dependent RNA helicase	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        NCU01234 eukaryotic initiation factor 4A-12	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NCU03932 hypothetical protein	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        NCU00159 Sin3-associated polypeptide Sap18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        NCU09901 hypothetical protein	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        NCU03285 hypothetical protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        NCU07865 THO complex subunit Tho1	K12878 THOC1; THO complex subunit 1 
E        NCU07002 THO complex component	K12879 THOC2; THO complex subunit 2 
E        NCU02753 WD repeat-containing protein	K12880 THOC3; THO complex subunit 3 
E        NCU07421 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        NCU01793 RNA binding domain-containing protein	K12881 THOC4; THO complex subunit 4 
E        NCU03239 hypothetical protein	K13174 THOC5; THO complex subunit 5 
D      TREX-2 complex
E        NCU16773 hypothetical protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        NCU07913 hypothetical protein	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        NCU09871 centrin 3	K16466 CETN3; centrin-3 
E        NCU01288 hypothetical protein	K23719 SAC3; nuclear mRNA export protein SAC3 
D      Nuclear pore complex
E        NCU04059 hypothetical protein	K09291 TPR; nucleoprotein TPR 
E        NCU04288 Poly(A)+ RNA export protein	K14298 RAE1; mRNA export factor 
E        NCU04063 protein transporter sec-13	K14004 SEC13; protein transport protein SEC13 
E        NCU02473 nucleoporin Nup44	K14308 NUP54; nuclear pore complex protein Nup54 
E        NCU02808 hypothetical protein	K14306 NUP62; nuclear pore complex protein Nup62 
E        NCU01702 nuclear pore protein	K14309 NUP93; nuclear pore complex protein Nup93 
E        NCU04784 hypothetical protein	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        NCU09814 hypothetical protein	K14301 NUP107; nuclear pore complex protein Nup107 
E        NCU04007 hypothetical protein	K14300 NUP133; nuclear pore complex protein Nup133 
E        NCU00199 hypothetical protein	K14311 NUP188; nuclear pore complex protein Nup188 
E        NCU04463 non-repetitive nucleoporin	K14312 NUP155; nuclear pore complex protein Nup155 
E        NCU02742 hypothetical protein	K14303 NUP160; nuclear pore complex protein Nup160 
E        NCU00273 hypothetical protein	K14310 NUP205; nuclear pore complex protein Nup205 
E        NCU07655 hypothetical protein	K14307 NUPL1; nucleoporin p58/p45 
E        NCU06776 hypothetical protein	K14315 NDC1; nucleoporin NDC1 
E        NCU04376 hypothetical protein	K14299 SEH1; nucleoporin SEH1 
E        NCU08604 hypothetical protein	K18715 NUP159; nucleoporin NUP159 
E        NCU06894 hypothetical protein	K18716 NUP42; nucleoporin NUP42 
E        NCU00209 hypothetical protein	K18719 NUP82; nucleoporin NUP82 
E        NCU09871 centrin 3	K16466 CETN3; centrin-3 
E        NCU01198 gle-1; gle-1 protein	K18723 GLE1; nucleoporin GLE1 
E        NCU09317 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        NCU03631 hypothetical protein	K14285 NXT1_2; NTF2-related export protein 1/2 
E        NCU06674 hypothetical protein	K18724 POM34; nucleoporin POM34 
E        NCU10747 hypothetical protein	K18725 POM152; nucleoporin POM152 
D      Ran-mediated transport factors
E        NCU09269 ran; ran-like	K07936 RAN; GTP-binding nuclear protein Ran 
E        NCU01928 UBX domain-containing protein	K18726 FAF2; FAS-associated factor 2 
E        NCU00018 cell division control protein Cdc48	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        NCU01820 exportin-1	K14290 XPO1; exportin-1 
E        NCU03207 ran GTPase activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        NCU02076 eukaryotic translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NCU09546 translation initiation factor eIF4E3	K03259 EIF4E; translation initiation factor 4E 
E        NCU07420 eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        NCU07868 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        NCU00457 translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        NCU09093 DEAD box RNA helicase-PL10B	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NCU01369 ATP-dependent RNA helicase ded-1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NCU09657 hypothetical protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        NCU04799 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        NCU01857 DEAD/DEAH box RNA helicase	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        NCU08267 activating signal cointegrator 1 complex subunit 3	K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] 
E        NCU08678 translation machinery-associated protein 20	K07575 MCTS; malignant T-cell-amplified sequence 
E        NCU02984 translation machinery-associated protein 22	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        NCU03232 RNA binding protein Pym	K14294 WIBG; partner of Y14 and mago 
E        NCU17030 heterogeneous nuclear ribonucleoprotein HRP1	K14411 MSI; RNA-binding protein Musashi 
E        NCU03981 elongation factor Tu GTP binding domain-containing protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        NCU09161 translation factor pelota	K06965 PELO; protein pelota 
E        NCU03946 polyadenylate-binding protein 2	K14396 PABPN1; polyadenylate-binding protein 2 
E        NCU01160 ATP-dependent RNA helicase dbp-5	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        NCU08036 pre-mRNA-splicing factor syf-1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        NCU11259 hypothetical protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        NCU05513 hypothetical protein	K11493 RCC1; regulator of chromosome condensation 
E        NCU03001 hypothetical protein	K11493 RCC1; regulator of chromosome condensation 
E        NCU06594 SAC3/GANP domain-containing protein	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        NCU00410 eukaryotic release factor 1	K03265 ETF1; peptide chain release factor subunit 1 
E        NCU04790 eukaryotic peptide chain release factor GTP-binding subunit	K03267 ERF3; peptide chain release factor subunit 3 
E        NCU04242 prd-6; period-6	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        NCU05267 nonsense-mediated mRNA decay factor	K14327 UPF2; regulator of nonsense transcripts 2 
E        NCU03435 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        NCU06630 pph-1; protein phosphatase-1	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        NCU00488 protein phosphatase PP2A regulatory subunit A	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        NCU09377 rgb-1; B-regulatory subunit-1	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        NCU03786 serine/threonine protein phosphatase 2A	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        NCU09657 hypothetical protein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        NCU09513 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        NCU09380 pumilio domain-containing protein	K14844 PUF6; pumilio homology domain family member 6 
E        NCU06251 KH domain RNA-binding protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        NCU09237 KH domain RNA binding protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        NCU01440 myosin-2	K10357 MYO5; myosin V 
E        NCU07036 hypothetical protein	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        NCU09352 far upstream element-binding protein 2	K13210 FUBP; far upstream element-binding protein 
E        NCU02003 tef-1; translation elongation factor-1	K03231 EEF1A; elongation factor 1-alpha 
E        NCU03826 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
E        NCU10521 gst-4; glutathione S-transferase-4	K03233 EEF1G; elongation factor 1-gamma 
D      Other mRNA localization factors
E        NCU01197 gul-1; gulliver-1	K18748 SSD1; protein SSD1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        NCU06678 exonuclease Kem1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        NCU09434 sms-2; suppressor of meiotic silencing-2	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        NCU02076 eukaryotic translation initiation factor 4E	K03259 EIF4E; translation initiation factor 4E 
E        NCU09546 translation initiation factor eIF4E3	K03259 EIF4E; translation initiation factor 4E 
E        NCU04242 prd-6; period-6	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        NCU09093 DEAD box RNA helicase-PL10B	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NCU01369 ATP-dependent RNA helicase ded-1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        NCU06149 ATP-dependent RNA helicase dhh-1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        NCU03366 hypothetical protein	K18749 LSM14; protein LSM14 
E        NCU09159 hypothetical protein	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        NCU03690 importin beta-2 subunit	K18752 TNPO1; transportin-1 
E        NCU06240 pkac-1; protein kinase A catalytic subunit-1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        NCU00682 pkac-2; protein kinase A catalytic subunit-2	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        NCU02720 hypothetical protein	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        NCU07889 hypothetical protein	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        NCU01601 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        NCU07382 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        NCU09512 U6 small nuclear ribonucleoprotein	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        NCU07683 small nuclear ribonucleoprotein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        NCU03766 small nuclear ribonucleoprotein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        NCU10352 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        NCU01930 U6 snRNP-associated protein Lsm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        NCU03085 small nuclear ribonucleoprotein Lsm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        NCU01440 myosin-2	K10357 MYO5; myosin V 
E        NCU09132 tba-1; tubulin alpha-1	K07374 TUBA; tubulin alpha 
E        NCU09468 tba-2; tubulin alpha-2	K07374 TUBA; tubulin alpha 
E        NCU04766 Ccr4-Not transcription complex subunit	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        NCU11372 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        NCU03855 CCR4-NOT transcription complex	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        NCU04073 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        NCU07779 ccr4; glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        NCU09001 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        NCU10733 PAB-dependent poly(A)-specific ribonuclease subunit pan-2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        NCU01929 PAB-dependent poly(A)-specific ribonuclease subunit pan-3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        NCU06540 topisomerase II associated protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        NCU00427 hypothetical protein	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        NCU05267 nonsense-mediated mRNA decay factor	K14327 UPF2; regulator of nonsense transcripts 2 
E        NCU03435 hypothetical protein	K14328 UPF3; regulator of nonsense transcripts 3 
E        NCU02661 DNA-directed RNA polymerase II polypeptide	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
D      Stress granule specific factors
E        NCU07874 nuclear and cytoplasmic polyadenylated RNA-binding protein pub1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        NCU04799 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        NCU07574 hypothetical protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        NCU06099 hypothetical protein	K15026 EIF2A; translation initiation factor 2A 
E        NCU02208 un-10; unknown-10	K03253 EIF3B; translation initiation factor 3 subunit B 
E        NCU07420 eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        NCU01234 eukaryotic initiation factor 4A-12	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        NCU00457 translation initiation factor 4B	K03258 EIF4B; translation initiation factor 4B 
E        NCU07868 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        NCU05810 cpc-2; cross pathway control-2	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        NCU09317 hypothetical protein	K14284 NXF; nuclear RNA export factor 
E        NCU01525 hda-1; histone deacetylase-1	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        NCU07889 hypothetical protein	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        NCU06149 ATP-dependent RNA helicase dhh-1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        NCU00427 hypothetical protein	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        NCU06540 topisomerase II associated protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        NCU01601 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        NCU07382 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        NCU09512 U6 small nuclear ribonucleoprotein	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        NCU07683 small nuclear ribonucleoprotein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        NCU03766 small nuclear ribonucleoprotein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        NCU10352 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        NCU01930 U6 snRNP-associated protein Lsm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        NCU03085 small nuclear ribonucleoprotein Lsm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        NCU06678 exonuclease Kem1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        NCU01643 5'-3' exoribonuclease 2	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        NCU06998 scavenger mRNA decapping enzyme	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        NCU04155 exosome component 1	K07573 CSL4; exosome complex component CSL4 
E        NCU04009 exosome complex exonuclease Rrp4	K03679 RRP4; exosome complex component RRP4 
E        NCU00693 exosome complex exonuclease RRP40	K03681 RRP40; exosome complex component RRP40 
E        NCU00812 exosome complex exonuclease RRP41	K11600 RRP41; exosome complex component RRP41 
E        NCU03268 hypothetical protein	K12590 RRP46; exosome complex component RRP46 
E        NCU08026 3' exoribonuclease	K12587 MTR3; exosome complex component MTR3 
E        NCU01806 3' exoribonuclease	K12589 RRP42; exosome complex component RRP42 
E        NCU03159 3' exoribonuclease	K12586 RRP43; exosome complex component RRP43 
E        NCU00334 3' exoribonuclease	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        NCU03065 mitotic control protein dis3	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        NCU02256 exosome complex exonuclease Rrp6	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        NCU16328 hypothetical protein	K12592 C1D; exosome complex protein LRP1 
E        NCU04472 DEAD/DEAH box helicase	K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] 
D      TRAMP complex
E        NCU05588 topoisomerase TRF4	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        NCU04617 hypothetical protein	K12597 AIR1_2; protein AIR1/2 
E        NCU03363 frh; FRQ-interacting RNA helicase	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        NCU01857 DEAD/DEAH box RNA helicase	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        NCU09438 translation repressor/antiviral protein Ski3	K12600 SKI3; superkiller protein 3 
E        NCU03517 Ski8	K12601 SKI8; superkiller protein 8 
D      Ccr4-NOT complex
E        NCU07779 ccr4; glucose-repressible alcohol dehydrogenase transcriptional effector	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        NCU04766 Ccr4-Not transcription complex subunit	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        NCU11372 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        NCU03855 CCR4-NOT transcription complex	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        NCU04073 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        NCU09001 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        NCU07071 cell differentiation protein rcd1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        NCU04097 ABC transporter	K12608 CAF16; CCR4-NOT complex subunit CAF16 
E        NCU02750 PH domain-containing protein	K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120 
D      Pan complex
E        NCU10733 PAB-dependent poly(A)-specific ribonuclease subunit pan-2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        NCU01929 PAB-dependent poly(A)-specific ribonuclease subunit pan-3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        NCU07559 hypothetical protein	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        NCU06998 scavenger mRNA decapping enzyme	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        NCU00120 hypothetical protein	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        NCU00311 VTS1	K27407 VTS1; RNA-binding protein VTS1 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        NCU01762 nucleolar RNAse III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        NCU16377 oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        NCU10042 emp-7; embden-meyerhof pathway-7	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        NCU01870 Eno3 protein	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        NCU00629 emp-3; embden-meyerhof pathway-3	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        NCU08693 hsp70-5; heat shock protein 70-5	K04043 dnaK; molecular chaperone DnaK 
E        NCU01589 hsp60; heat shock protein 60	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        NCU04009 exosome complex exonuclease Rrp4	K03679 RRP4; exosome complex component RRP4 
E        NCU04155 exosome component 1	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        NCU00812 exosome complex exonuclease RRP41	K11600 RRP41; exosome complex component RRP41 
E        NCU01806 3' exoribonuclease	K12589 RRP42; exosome complex component RRP42 
D      Others
!
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#Last updated: April 25, 2024