+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Neodiprion fabricii</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        124176795 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        124181934 mRNA-capping enzyme	K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74] 
E        124185349 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        124174439 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
E        124177328 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 isoform X1	K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296] 
D      Cap binding complex
E        124183772 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        124175242 nuclear cap-binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        124187152 cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        124176721 protein CLP1 homolog	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        124183692 cleavage and polyadenylation specificity factor subunit 1 isoform X1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        124176534 probable cleavage and polyadenylation specificity factor subunit 2 isoform X1	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        124178982 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        124178690 cleavage and polyadenylation specificity factor subunit 4	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        124179352 uncharacterized protein LOC124179352 isoform X1	K15542 PFS2; polyadenylation factor subunit 2 
E        124176156 WD repeat-containing protein 82	K14962 WDR82; COMPASS component SWD2 
E        124177239 serine/threonine-protein phosphatase alpha-2 isoform	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        124185606 serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        124180027 RNA polymerase II subunit A C-terminal domain phosphatase SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        124181241 cleavage stimulation factor subunit 1	K14406 CSTF1; cleavage stimulation factor subunit 1 
E        124179310 cleavage stimulation factor subunit 2 isoform X1	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        124180491 protein suppressor of forked	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        124176778 symplekin	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        124175271 small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        124174785 small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        124177292 probable small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        124186257 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        124179115 probable small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        124182445 U7 snRNA-associated Sm-like protein LSm10	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        124179645 U7 snRNA-associated Sm-like protein LSm11	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        124176534 probable cleavage and polyadenylation specificity factor subunit 2 isoform X1	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        124178982 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        124179310 cleavage stimulation factor subunit 2 isoform X1	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        124176778 symplekin	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        124175061 transcription elongation factor SPT4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        124179580 transcription elongation factor SPT5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        124182821 N6-adenosine-methyltransferase subunit METTL3	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        124174429 N6-adenosine-methyltransferase non-catalytic subunit	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        124183492 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase isoform X1	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
E        124184280 RNA-binding protein spenito	K13190 RBM15; RNA-binding protein 15 
E        124176043 zinc finger CCCH domain-containing protein 13-like	K22909 ZC3H13; zinc finger CCCH domain-containing protein 13 
E        124180150 E3 ubiquitin-protein ligase Hakai	K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27] 
D      Poly(A) addition factors
E        124186266 poly(A) polymerase type 3	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        124184662 poly(A) RNA polymerase gld-2 homolog A-like isoform X1	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        124181103 RNA-binding protein 27 isoform X1	K13192 RBM26; RNA-binding protein 26 
C    Other processing factors
D      124184459 DNA/RNA-binding protein KIN17	K13102 KIN; DNA/RNA-binding protein KIN17 
D      124186330 methyltransferase-like protein 22 isoform X1	K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-] 
D      124186971 terminal nucleotidyltransferase 5C isoform X1	K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19] 
D      124183945 serrate RNA effector molecule homolog isoform X1	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        124187169 RNA-binding protein 8A	K12876 RBM8A; RNA-binding protein 8A 
E        124175060 protein mago nashi homolog	K12877 MAGOH; protein mago nashi 
E        124175997 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        124179149 ATP-dependent RNA helicase WM6	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        124186921 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        124178517 coiled-coil domain-containing protein 174	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        124183026 histone deacetylase complex subunit SAP18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        124176544 pinin	K13114 PNN; pinin 
E        124180619 RNA-binding protein with serine-rich domain 1-B-like isoform X1	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
D      TREX complex
E        124175035 THO complex subunit 1 isoform X1	K12878 THOC1; THO complex subunit 1 
E        124185777 THO complex subunit 2 isoform X1	K12879 THOC2; THO complex subunit 2 
E        124175108 THO complex subunit 3	K12880 THOC3; THO complex subunit 3 
E        124175997 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        124183490 THO complex subunit 5 homolog	K13174 THOC5; THO complex subunit 5 
E        124186888 THO complex subunit 6	K13175 THOC6; THO complex subunit 6 
E        124186748 THO complex subunit 7 homolog isoform X1	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        124183605 PCI domain-containing protein 2	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        124187743 26S proteasome complex subunit SEM1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        124179155 transcription and mRNA export factor ENY2-like	K11368 ENY2; enhancer of yellow 2 transcription factor 
D      Nuclear pore complex
E        124176457 nucleoprotein TPR-like isoform X1	K09291 TPR; nucleoprotein TPR 
E        124179043 protein Rae1	K14298 RAE1; mRNA export factor 
E        124186695 protein SEC13 homolog	K14004 SEC13; protein transport protein SEC13 
E        124184786 nucleoporin Nup37	K14302 NUP37; nuclear pore complex protein Nup37 
E        124183426 nuclear pore complex protein Nup85	K14304 NUP85; nuclear pore complex protein Nup85 
E        124183250 nucleoporin Nup43	K14305 NUP43; nuclear pore complex protein Nup43 
E        124184335 nuclear pore complex protein Nup50	K14295 NUP50; nuclear pore complex protein Nup50 
E        124178911 nuclear pore complex protein Nup54	K14308 NUP54; nuclear pore complex protein Nup54 
E        124182194 nuclear pore glycoprotein p62	K14306 NUP62; nuclear pore complex protein Nup62 
E        124177772 nuclear pore complex protein Nup88	K14318 NUP88; nuclear pore complex protein Nup88 
E        124176148 nuclear pore complex protein Nup93-like isoform X1	K14309 NUP93; nuclear pore complex protein Nup93 
E        124179982 nuclear pore complex protein Nup98-Nup96 isoform X1	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        124186680 nuclear pore complex protein Nup107	K14301 NUP107; nuclear pore complex protein Nup107 
E        124182687 nuclear pore complex protein Nup133 isoform X1	K14300 NUP133; nuclear pore complex protein Nup133 
E        124175766 nuclear pore complex protein Nup153	K14296 NUP153; nuclear pore complex protein Nup153 
E        124185799 nuclear pore complex protein Nup155	K14312 NUP155; nuclear pore complex protein Nup155 
E        124180475 nuclear pore complex protein Nup160 homolog	K14303 NUP160; nuclear pore complex protein Nup160 
E        124179337 nucleoporin Nup35	K14313 NUP35; nuclear pore complex protein Nup53 
E        124176906 nuclear pore complex protein Nup205	K14310 NUP205; nuclear pore complex protein Nup205 
E        124183691 nuclear pore membrane glycoprotein 210	K14314 NUP210; nuclear pore complex protein Nup210 
E        124184579 nuclear pore complex protein Nup58-like isoform X1	K14307 NUPL1; nucleoporin p58/p45 
E        124187964 nucleoporin NDC1	K14315 NDC1; nucleoporin NDC1 
E        124181153 nucleoporin SEH1-A isoform X1	K14299 SEH1; nucleoporin SEH1 
E        124180308 aladin-like	K14320 AAAS; aladin 
E        124183489 mRNA export factor Gle1 isoform X1	K18723 GLE1; nucleoporin GLE1 
E        124179641 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124179642 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124182304 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124184722 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124174626 NTF2-related export protein	K14285 NXT1_2; NTF2-related export protein 1/2 
D      Ran-mediated transport factors
E        124174910 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        124179498 acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1	K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
E        124183727 ELAV-like protein 3 isoform X1	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        124183167 FAS-associated factor 2	K18726 FAF2; FAS-associated factor 2 
E        124183918 transitional endoplasmic reticulum ATPase TER94	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        124187735 protein N-lysine methyltransferase METTL21D-like isoform X1	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        124178197 exportin-1	K14290 XPO1; exportin-1 
E        124185138 exportin-7 isoform X1	K18460 XPO7; exportin-7 
E        124175349 ran GTPase-activating protein 1 isoform X1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        124176082 eukaryotic translation initiation factor 4E-like	K03259 EIF4E; translation initiation factor 4E 
E        124187148 eukaryotic translation initiation factor 4E type 2	K03259 EIF4E; translation initiation factor 4E 
E        124175211 eukaryotic initiation factor 4A-I	K03257 EIF4A; translation initiation factor 4A 
E        124184629 eukaryotic translation initiation factor 4 gamma 2 isoform X1	K03260 EIF4G; translation initiation factor 4G 
E        124187660 eukaryotic translation initiation factor 4B isoform X1	K03258 EIF4B; translation initiation factor 4B 
E        124176647 eukaryotic translation initiation factor 4H-like	K24086 EIF4H; translation initiation factor 4H 
E        124177799 eukaryotic translation initiation factor 4E-binding protein 3 isoform X1	K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
E        124184724 protein angel isoform X1	K18729 ANGEL; protein angel 
E        124184753 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        124185108 cytoplasmic FMR1-interacting protein isoform X1	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        124184780 gem-associated protein 5 isoform X1	K13133 GEMIN5; gem associated protein 5 
E        124184874 cytoplasmic polyadenylation element-binding protein 2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        124181455 ATP-dependent RNA helicase bel	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        124183849 polyadenylate-binding protein 1 isoform X1	K13126 PABPC; polyadenylate-binding protein 
E        124184976 polyadenylate-binding protein-interacting protein 2 isoform X1	K27470 PAIP2; polyadenylate-binding protein-interacting protein 2 
E        124186686 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        124176412 deformed epidermal autoregulatory factor 1	K23041 DEAF1; deformed epidermal autoregulatory factor 1 
E        124185297 malignant T-cell-amplified sequence 1 homolog	K07575 MCTS; malignant T-cell-amplified sequence 
E        124182115 density-regulated protein homolog isoform X1	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        124174649 partner of Y14 and mago	K14294 WIBG; partner of Y14 and mago 
E        124175496 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        124182895 RNA-binding protein Musashi homolog Rbp6 isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        124184414 RNA-binding protein Musashi homolog 2-like isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        124185043 heterogeneous nuclear ribonucleoprotein 27C-like isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        124174576 protein HBS1	K14416 HBS1; elongation factor 1 alpha-like protein 
E        124178759 protein pelota	K06965 PELO; protein pelota 
E        124184514 polyadenylate-binding protein 2-B isoform X1	K14396 PABPN1; polyadenylate-binding protein 2 
E        124180231 DEAD-box helicase Dbp80 isoform X1	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        124182957 pre-mRNA-splicing factor syf1 homolog	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        124180871 SAP domain-containing ribonucleoprotein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        124186662 regulator of chromosome condensation	K11493 RCC1; regulator of chromosome condensation 
E        124180426 transcriptional activator protein Pur-beta-like isoform X1	K21772 PURA; transcriptional activator protein Pur-alpha 
E        124185486 uncharacterized protein LOC124185486 isoform X1	K22415 ZC3H11; zinc finger CCCH domain-containing protein 11 
C    Surveillance factors
D      Surveillance complex
E        124185345 eukaryotic peptide chain release factor subunit 1 isoform X1	K03265 ETF1; peptide chain release factor subunit 1 
E        124176930 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1	K03267 ERF3; peptide chain release factor subunit 3 
E        124184660 regulator of nonsense transcripts 1 homolog	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        124183805 regulator of nonsense transcripts 2	K14327 UPF2; regulator of nonsense transcripts 2 
D      Protein phosphatase 2A
E        124178708 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        124176975 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        124177908 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        124179223 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        124180879 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        124186714 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        124176246 serine/threonine-protein kinase SMG1 isoform X1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        124178842 protein SMG5	K11125 SMG5; protein SMG5 
E        124179331 protein SMG8 isoform X1	K18734 SMG8; protein SMG8 
E        124174799 protein SMG9 isoform X1	K18735 SMG9; protein SMG9 
E        124185797 selenocysteine insertion sequence-binding protein 2-like	K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2 
E        124183630 probable ATP-dependent RNA helicase DHX34	K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6] 
E        124183427 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        124180919 protein penguin	K14844 PUF6; pumilio homology domain family member 6 
E        124174956 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        124188090 protein bicaudal D isoform X1	K18739 BICD; protein bicaudal D 
E        124174453 egalitarian protein homolog	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
E        124176199 actin-5C	K05692 ACTB_G1; actin beta/gamma 1 
E        124180867 actin-5C-like	K05692 ACTB_G1; actin beta/gamma 1 
E        124181242 actin-5C-like	K05692 ACTB_G1; actin beta/gamma 1 
E        124186041 actin-5, muscle-specific	K05692 ACTB_G1; actin beta/gamma 1 
E        124186048 actin-5, muscle-specific	K05692 ACTB_G1; actin beta/gamma 1 
E        124186055 actin, muscle	K05692 ACTB_G1; actin beta/gamma 1 
E        124181927 T-box transcription factor T-like	K10180 TBX6; T-box protein 6 
E        124175398 protein hairy-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        124188081 enhancer of split mbeta protein-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        124188082 enhancer of split mgamma protein-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        124188083 enhancer of split mbeta protein-like	K09090 HESN; hairy and enhancer of split, invertebrate 
D      Trans-acting binding proteins
E        124174666 far upstream element-binding protein 3 isoform X1	K13210 FUBP; far upstream element-binding protein 
E        124181730 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        124183465 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        124184726 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
E        124176255 arf-GAP domain and FG repeat-containing protein 1 isoform X1	K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1 
E        124181354 double-stranded RNA-binding protein Staufen homolog 2 isoform X1	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        124181005 polypyrimidine tract-binding protein 1 isoform X1	K13218 PTBP1; polypyrimidine tract-binding protein 1 
E        124178643 RNA-binding protein squid isoform X1	K03102 SQD; squid 
E        124183265 RNA-binding protein squid-like	K03102 SQD; squid 
E        124184874 cytoplasmic polyadenylation element-binding protein 2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
D      Other mRNA localization factors
E        124184753 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        124185108 cytoplasmic FMR1-interacting protein isoform X1	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        124175082 CUGBP Elav-like family member 2 isoform X1	K02177 BRU; bruno 
E        124186167 maternal protein exuperantia	K18745 EXU; maternal protein exuperantia 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        124181679 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        124183476 protein argonaute-2 isoform X1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        124185287 protein argonaute-2-like isoform X1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        124176082 eukaryotic translation initiation factor 4E-like	K03259 EIF4E; translation initiation factor 4E 
E        124187148 eukaryotic translation initiation factor 4E type 2	K03259 EIF4E; translation initiation factor 4E 
E        124184660 regulator of nonsense transcripts 1 homolog	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        124181455 ATP-dependent RNA helicase bel	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        124174994 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        124184939 RNA-binding protein MEX3B	K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
E        124186125 protein LSM14 homolog B isoform X1	K18749 LSM14; protein LSM14 
E        124184238 putative helicase MOV-10	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        124187752 transportin-1	K18752 TNPO1; transportin-1 
E        124176246 serine/threonine-protein kinase SMG1 isoform X1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        124178842 protein SMG5	K11125 SMG5; protein SMG5 
E        124178774 huntingtin isoform X1	K04533 HD; huntingtin 
E        124174408 protein bicaudal C isoform X1	K18756 BICC1; protein bicaudal C 
E        124175496 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        124183473 cAMP-dependent protein kinase catalytic subunit 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        124185987 cAMP-dependent protein kinase catalytic subunit beta-like	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        124185319 la-related protein 1B isoform X1	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        124184932 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        124185317 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        124176423 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        124174427 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        124175245 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        124174627 U6 snRNA-associated Sm-like protein LSm5 isoform X1	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        124187002 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        124186598 U6 snRNA-associated Sm-like protein LSm7 isoform X1	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        124175848 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        124180072 kinesin light chain isoform X1	K10407 KLC; kinesin light chain 
E        124174956 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        124177995 tubulin alpha-8 chain-like	K07374 TUBA; tubulin alpha 
E        124180181 tubulin alpha-1 chain-like	K07374 TUBA; tubulin alpha 
E        124182282 tubulin alpha-1 chain-like	K07374 TUBA; tubulin alpha 
E        124183122 tubulin alpha-1 chain-like	K07374 TUBA; tubulin alpha 
E        124183123 tubulin alpha-1 chain-like	K07374 TUBA; tubulin alpha 
E        124184035 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        124184746 tubulin alpha-1C chain-like	K07374 TUBA; tubulin alpha 
E        124185574 tubulin alpha-8 chain-like	K07374 TUBA; tubulin alpha 
E        124184874 cytoplasmic polyadenylation element-binding protein 2	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        124184780 gem-associated protein 5 isoform X1	K13133 GEMIN5; gem associated protein 5 
E        124176271 trinucleotide repeat-containing gene 6C protein-like isoform X1	K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
E        124174595 CCR4-NOT transcription complex subunit 1 isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        124179864 CCR4-NOT transcription complex subunit 2-like	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        124174812 CCR4-NOT transcription complex subunit 3 isoform X1	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        124187792 CCR4-NOT transcription complex subunit 6 isoform X1	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        124185268 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        124182417 DIS3-like exonuclease 2 isoform X1	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        124180997 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        124175396 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        124182652 protein BTG2-like	K14443 TOB; protein Tob/BTG 
E        124183741 protein Tob1-like isoform X1	K14443 TOB; protein Tob/BTG 
E        124186661 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        124176469 enhancer of mRNA-decapping protein 4	K12616 EDC4; enhancer of mRNA-decapping protein 4 
E        124185098 nanos homolog 1	K18760 NANOS2; protein nanos 2 
E        124183805 regulator of nonsense transcripts 2	K14327 UPF2; regulator of nonsense transcripts 2 
E        124183416 E3 ubiquitin-protein ligase TRIM71	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        124181074 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        124180950 YTH domain-containing family protein 1 isoform X1	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        124185439 nucleolysin TIA-1 isoform X1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        124186691 nucleolysin TIAR	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        124183849 polyadenylate-binding protein 1 isoform X1	K13126 PABPC; polyadenylate-binding protein 
E        124181354 double-stranded RNA-binding protein Staufen homolog 2 isoform X1	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        124184753 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        124176055 eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        124186251 eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        124175211 eukaryotic initiation factor 4A-I	K03257 EIF4A; translation initiation factor 4A 
E        124186921 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        124187660 eukaryotic translation initiation factor 4B isoform X1	K03258 EIF4B; translation initiation factor 4B 
E        124184629 eukaryotic translation initiation factor 4 gamma 2 isoform X1	K03260 EIF4G; translation initiation factor 4G 
E        124182215 ribosomal protein S6 kinase 2 beta isoform X1	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        124178705 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        124179641 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124179642 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124182304 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124184722 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        124176865 histone deacetylase 6 isoform X1	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
E        124185726 tudor domain-containing protein 3 isoform X1	K18404 TDRD3; tudor domain-containing protein 3 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        124184932 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        124174994 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        124186661 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        124176469 enhancer of mRNA-decapping protein 4	K12616 EDC4; enhancer of mRNA-decapping protein 4 
D      Lsm complex
E        124185317 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        124176423 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        124174427 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        124175245 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        124174627 U6 snRNA-associated Sm-like protein LSm5 isoform X1	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        124187002 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        124186598 U6 snRNA-associated Sm-like protein LSm7 isoform X1	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        124175848 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        124181679 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        124182689 5'-3' exoribonuclease 2 homolog isoform X1	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        124186169 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        124188177 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
C    3'-5' decay
D      Core exosome factors
E        124181275 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
E        124175027 exosome complex component RRP4 isoform X1	K03679 RRP4; exosome complex component RRP4 
E        124182113 exosome complex component RRP40 isoform X1	K03681 RRP40; exosome complex component RRP40 
E        124177632 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        124175328 exosome complex component RRP46	K12590 RRP46; exosome complex component RRP46 
E        124174935 exosome complex component MTR3-like isoform X1	K12587 MTR3; exosome complex component MTR3 
E        124181398 exosome complex component RRP42 isoform X1	K12589 RRP42; exosome complex component RRP42 
E        124184469 exosome complex component RRP43-like	K12586 RRP43; exosome complex component RRP43 
E        124184408 exosome complex component RRP45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        124186861 exosome complex exonuclease RRP44	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        124179428 exosome component 10	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        124179564 nuclear nucleic acid-binding protein C1D	K12592 C1D; exosome complex protein LRP1 
E        124176500 M-phase phosphoprotein 6	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
D      TRAMP complex
E        124177615 terminal nucleotidyltransferase 4B-like isoform X1	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        124185188 exosome RNA helicase MTR4	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        124186686 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        124183413 tetratricopeptide repeat protein 37 isoform X1	K12600 SKI3; superkiller protein 3 
E        124177262 WD repeat-containing protein 61-like	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        124187792 CCR4-NOT transcription complex subunit 6 isoform X1	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        124174595 CCR4-NOT transcription complex subunit 1 isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        124179864 CCR4-NOT transcription complex subunit 2-like	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        124174812 CCR4-NOT transcription complex subunit 3 isoform X1	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        124185268 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        124181202 CCR4-NOT transcription complex subunit 9	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        124183594 CCR4-NOT transcription complex subunit 10-B	K12607 CNOT10; CCR4-NOT transcription complex subunit 10 
D      Pan complex
E        124180997 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        124175396 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        124183198 poly(A)-specific ribonuclease PARN-like isoform X1	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        124183566 pre-piRNA 3'-exonuclease trimmer-like	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        124174481 ATP-dependent DNA/RNA helicase DHX36-like isoform X1	K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] 
E        124182652 protein BTG2-like	K14443 TOB; protein Tob/BTG 
E        124183741 protein Tob1-like isoform X1	K14443 TOB; protein Tob/BTG 
E        124176761 nocturnin isoform X1	K18764 NOCT; nocturnin [EC:3.1.3.108] 
E        124186169 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        124175941 2',5'-phosphodiesterase 12	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
E        124188177 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
E        124185823 protein Smaug homolog 1 isoform X1	K27396 SMG; protein Smaug 
E        124179127 focadhesin isoform X1	K27498 FOCAD; focadhesin 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        124179551 ribonuclease 3	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        124182765 oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        124176323 enolase isoform X1	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        124182569 polyribonucleotide nucleotidyltransferase 1, mitochondrial	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        124176398 ATP-dependent 6-phosphofructokinase isoform X1	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        124185839 heat shock 70 kDa protein cognate 5	K04043 dnaK; molecular chaperone DnaK 
E        124181533 heat shock protein 60A-like	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        124175027 exosome complex component RRP4 isoform X1	K03679 RRP4; exosome complex component RRP4 
E        124181275 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        124177632 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        124181398 exosome complex component RRP42 isoform X1	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
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#Last updated: August 27, 2025