+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Nocardia iowensis

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type D KV110_15745 acyltransferase domain-containing protein K21254 calO5; orsellinic acid synthase [EC:2.3.1.-] B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E KV110_14185 SRPBCC family protein K14670 whiEVI; aromatase E KV110_14160 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E KV110_14170 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14175 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14180 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Nonaketide PKS E KV110_14170 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14175 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14180 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Decaketide PKS E KV110_14170 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14175 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E KV110_14180 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein B Type III PKS C Plant type C Fungal type C Bacterial type D KV110_15715 type III polyketide synthase K16424 dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase [EC:2.3.1.246] D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D KV110_03355 MbtH family protein K05375 mbtH; MbtH protein D KV110_37285 MbtH family protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D KV110_22505 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_22835 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_32010 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35825 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35895 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_33850 amino acid adenylation domain-containing protein K02364 entF; L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72] C Bacillibactin synthetase D KV110_22505 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_22835 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_32010 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35825 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35895 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase D KV110_22880 amino acid adenylation domain-containing protein K12239 pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69] D KV110_22875 amino acid adenylation domain-containing protein K12240 pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] D KV110_35845 amino acid adenylation domain-containing protein K12240 pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] C Mycobactin synthetase D KV110_03815 AMP-binding protein K04787 mbtA; mycobactin salicyl-AMP ligase [EC:6.3.2.-] D KV110_03820 amino acid adenylation domain-containing protein K04788 mbtB; mycobactin phenyloxazoline synthetase D KV110_04565 polyketide synthase K04790 mbtC; mycobactin polyketide synthetase MbtC D KV110_04570 nbtC; nocobactin polyketide synthase NbtC K04791 mbtD; mycobactin polyketide synthetase MbtD D KV110_04550 amino acid adenylation domain-containing protein K04789 mbtE; mycobactin peptide synthetase MbtE D KV110_04555 amino acid adenylation domain-containing protein K04792 mbtF; mycobactin peptide synthetase MbtF C Vibriobactin synthetase D KV110_22505 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_22835 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_32010 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35825 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35895 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D KV110_22505 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_22835 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_32010 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35825 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35895 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D KV110_22505 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_22835 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_32010 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35825 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D KV110_35895 AMP-binding protein K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C KV110_01240 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C KV110_15580 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C KV110_16390 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C KV110_18315 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C KV110_27215 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C KV110_10810 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_17105 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_18980 hypothetical protein K21159 sgcF; epoxide hydrolase C KV110_19005 epoxide hydrolase 1 K21159 sgcF; epoxide hydrolase C KV110_19295 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_23470 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_25800 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_34460 epoxide hydrolase 1 K21159 sgcF; epoxide hydrolase C KV110_37035 epoxide hydrolase K21159 sgcF; epoxide hydrolase C KV110_38955 epoxide hydrolase 1 K21159 sgcF; epoxide hydrolase C KV110_24360 epoxide hydrolase 1 K21159 sgcF; epoxide hydrolase C KV110_15725 enoyl-CoA hydratase/isomerase family protein K16427 dpgC; (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase [EC:1.13.11.80] C KV110_14165 cupin domain-containing protein K14673 whiEII; putative monooxygenase B Methylase C KV110_22915 methyltransferase K20421 ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C KV110_31495 DUF1702 family protein K21160 sgcE2; enediyne biosynthesis protein E2 C KV110_31480 CRTAC1 family protein K21162 sgcE4; enediyne biosynthesis protein E4 C KV110_31485 enediyne biosynthesis protein K21163 sgcE5; enediyne biosynthesis protein E5 C KV110_31490 flavin reductase family protein K21185 sgcE6; flavin reductase # ANonribosomal peptide tailoring proteins B Reductase C KV110_22870 Gfo/Idh/MocA family oxidoreductase K12241 pchG; pyochelin biosynthesis protein PchG B Thioesterase B Oxygenase C KV110_04540 lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein K04793 mbtG; mycobactin lysine-N-oxygenase B Glycosyltransferase B Aminotransferase B Others C KV110_08485 hypothetical protein K16105 vioL; carbamoyltransferase C KV110_15720 enoyl-CoA hydratase/isomerase family protein K16425 dpgB; isomerase DpgB C KV110_15725 enoyl-CoA hydratase/isomerase family protein K16427 dpgC; (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase [EC:1.13.11.80] C KV110_15730 enoyl-CoA hydratase/isomerase family protein K16426 dpgD; dehydration protein DpgD C KV110_15865 amino acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024