+D GENES KO #

  KEGG Orthology (KO) - Nitrosopumilus sp. K4

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:nip00010] D NsoK4_00380 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D NsoK4_02665 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D NsoK4_05575 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D NsoK4_03015 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D NsoK4_03970 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D NsoK4_05905 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D NsoK4_08035 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D NsoK4_05665 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D NsoK4_03010 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D NsoK4_06350 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D NsoK4_06345 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_06590 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00020 Citrate cycle (TCA cycle) [PATH:nip00020] D NsoK4_02275 citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1] D NsoK4_00935 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3] D NsoK4_01365 isocitrate/isopropylmalate dehydrogenase family protein K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] D NsoK4_06350 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D NsoK4_06345 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D NsoK4_02145 CoA-binding protein K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D NsoK4_02140 acetate--CoA ligase family protein K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D NsoK4_07565 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D NsoK4_07550 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D NsoK4_07560 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D NsoK4_07555 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_06590 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00030 Pentose phosphate pathway [PATH:nip00030] D NsoK4_00380 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D NsoK4_07315 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D NsoK4_07320 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D NsoK4_07310 fsa; fructose-6-phosphate aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D NsoK4_07835 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_09430 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D NsoK4_02210 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D NsoK4_02665 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D NsoK4_05575 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] C 00040 Pentose and glucuronate interconversions D NsoK4_02350 zinc-dependent dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] C 00051 Fructose and mannose metabolism [PATH:nip00051] D NsoK4_08415 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D NsoK4_00380 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_05645 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D NsoK4_06295 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D NsoK4_00450 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D NsoK4_02350 zinc-dependent dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] D NsoK4_02665 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D NsoK4_05575 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D NsoK4_03015 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:nip00052] D NsoK4_05660 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D NsoK4_08865 NAD(P)-dependent oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_00535 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_08495 SDR family NAD(P)-dependent oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00053 Ascorbate and aldarate metabolism C 00500 Starch and sucrose metabolism [PATH:nip00500] D NsoK4_00385 rfbF; glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_00380 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D NsoK4_08415 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:nip00520] D NsoK4_05940 peptidase K01183 E3.2.1.14; chitinase [EC:3.2.1.14] D NsoK4_08415 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D NsoK4_07145 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D NsoK4_05650 GNAT family N-acetyltransferase K00621 GNPNAT1; glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4] D NsoK4_08535 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_08845 NAD-dependent epimerase/dehydratase family protein K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1] D NsoK4_05660 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D NsoK4_08865 NAD(P)-dependent oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_00535 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_08495 SDR family NAD(P)-dependent oxidoreductase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D NsoK4_00380 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D NsoK4_05645 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D NsoK4_06295 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D NsoK4_00450 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D NsoK4_08860 DegT/DnrJ/EryC1/StrS family aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102] D NsoK4_00385 rfbF; glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33] C 00620 Pyruvate metabolism [PATH:nip00620] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_06350 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D NsoK4_06345 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_08610 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D NsoK4_04130 VOC family protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_06590 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D NsoK4_03010 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_02375 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:nip00630] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_02275 citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1] D NsoK4_00935 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_03000 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D NsoK4_02975 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D NsoK4_02995 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D NsoK4_06360 D-glycerate dehydrogenase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26] D NsoK4_04965 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09330 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D NsoK4_02210 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D NsoK4_07810 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] C 00640 Propanoate metabolism [PATH:nip00640] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_03000 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D NsoK4_02975 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D NsoK4_02995 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D NsoK4_02140 acetate--CoA ligase family protein K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D NsoK4_02145 CoA-binding protein K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism [PATH:nip00650] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_02830 phaC; class III poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D NsoK4_02835 hypothetical protein K22881 phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE D NsoK4_07565 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D NsoK4_07550 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D NsoK4_07560 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D NsoK4_07555 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D NsoK4_07890 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] D NsoK4_06350 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D NsoK4_06345 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D NsoK4_03960 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D NsoK4_02365 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_06400 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_02370 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:nip00660] D NsoK4_02365 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_06400 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_02370 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D NsoK4_02140 acetate--CoA ligase family protein K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D NsoK4_02145 CoA-binding protein K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D NsoK4_06305 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06315 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06300 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06310 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_02380 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:nip00562] D NsoK4_07505 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D NsoK4_05115 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D NsoK4_03015 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:nip00190] D NsoK4_07465 NADH-quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D NsoK4_07460 nuoB; NADH-quinone oxidoreductase subunit NuoB K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D NsoK4_07450 NADH-quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D NsoK4_07445 nuoH; NADH-quinone oxidoreductase subunit NuoH K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] D NsoK4_07440 NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] D NsoK4_07420 NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] D NsoK4_07425 NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] D NsoK4_07415 NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D NsoK4_09255 NAD(P)/FAD-dependent oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D NsoK4_07565 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D NsoK4_07550 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D NsoK4_07560 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D NsoK4_07555 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D NsoK4_00560 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D NsoK4_01880 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08475 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08020 cbb3-type cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9] D NsoK4_08025 cupredoxin domain-containing protein K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D NsoK4_09940 V-type ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D NsoK4_09945 V-type ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D NsoK4_09900 V-type ATPase subunit K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D NsoK4_09950 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D NsoK4_09935 V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D NsoK4_02345 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D NsoK4_00265 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D NsoK4_09930 ATPase K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D NsoK4_09955 ATPase K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D NsoK4_02070 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:nip00710] D NsoK4_05905 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D NsoK4_03970 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D NsoK4_07315 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D NsoK4_07320 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D NsoK4_07835 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D NsoK4_03015 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D NsoK4_07310 fsa; fructose-6-phosphate aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D NsoK4_06590 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D NsoK4_03010 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] C 00720 Other carbon fixation pathways [PATH:nip00720] D NsoK4_03010 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07565 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D NsoK4_07550 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D NsoK4_07560 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D NsoK4_07555 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D NsoK4_02145 CoA-binding protein K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D NsoK4_02140 acetate--CoA ligase family protein K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D NsoK4_07895 acetate--CoA ligase family protein K18593 E6.2.1.56; 4-hydroxybutyrate---CoA ligase (ADP-forming) [EC:6.2.1.56] D NsoK4_07890 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] D NsoK4_02700 3-hydroxyacyl-CoA dehydrogenase family protein K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_06350 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D NsoK4_06345 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D NsoK4_00935 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3] D NsoK4_07480 ATP-grasp domain-containing protein K18603 K18603; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] D NsoK4_07485 acyl-CoA carboxylase subunit beta K18604 K18604; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] D NsoK4_07475 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit K18605 K18605; biotin carboxyl carrier protein D NsoK4_02215 iron-containing alcohol dehydrogenase K18602 K18602; malonic semialdehyde reductase [EC:1.1.1.-] D NsoK4_01520 acetate--CoA ligase family protein K18594 K18594; 3-hydroxypropionyl-CoA synthetase (ADP-forming) [EC:6.2.1.-] D NsoK4_01525 enoyl-CoA hydratase/isomerase family protein K15019 K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116] D NsoK4_03000 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D NsoK4_02995 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D NsoK4_02975 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D NsoK4_02170 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 00680 Methane metabolism [PATH:nip00680] D NsoK4_00795 ammonia monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39] D NsoK4_00780 ammonia monooxygenase K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B D NsoK4_00785 ammonia monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C D NsoK4_09330 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D NsoK4_02210 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_02665 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D NsoK4_05575 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D NsoK4_09640 tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_08035 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D NsoK4_05665 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D NsoK4_01690 D-2-hydroxyacid dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D NsoK4_05070 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D NsoK4_05355 cofH; 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D NsoK4_05350 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32] D NsoK4_05240 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D NsoK4_05235 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D NsoK4_05065 cofE; coenzyme F420-0:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] C 00910 Nitrogen metabolism [PATH:nip00910] D NsoK4_01685 multicopper oxidase domain-containing protein K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1] D NsoK4_00795 ammonia monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39] D NsoK4_00780 ammonia monooxygenase K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B D NsoK4_00785 ammonia monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C D NsoK4_01505 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] C 00920 Sulfur metabolism [PATH:nip00920] D NsoK4_01610 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D NsoK4_01620 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D NsoK4_01615 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D NsoK4_08950 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D NsoK4_09080 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D NsoK4_09075 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D NsoK4_08955 phosphoadenylyl-sulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D NsoK4_05020 nitrite/sulfite reductase K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1] D NsoK4_09370 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D NsoK4_09920 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_05015 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_06205 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_00710 pyridoxal-phosphate dependent enzyme K01738 cysK; cysteine synthase [EC:2.5.1.47] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:nip00061] D NsoK4_08270 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:nip00071] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:nip00561] D NsoK4_02210 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D NsoK4_08845 NAD-dependent epimerase/dehydratase family protein K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1] C 00564 Glycerophospholipid metabolism [PATH:nip00564] D NsoK4_09740 NAD(P)-dependent glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D NsoK4_09320 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D NsoK4_05210 NAD(P)/FAD-dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:nip00230] D NsoK4_09810 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_09430 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D NsoK4_03720 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D NsoK4_02160 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D NsoK4_02185 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D NsoK4_03715 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D NsoK4_03700 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D NsoK4_03710 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D NsoK4_05380 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D NsoK4_04095 5-(carboxyamino)imidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D NsoK4_04100 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D NsoK4_03740 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D NsoK4_01005 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D NsoK4_03660 formate--phosphoribosylaminoimidazolecarboxamide ligase family protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D NsoK4_04330 formate--phosphoribosylaminoimidazolecarboxamide ligase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D NsoK4_01255 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D NsoK4_08375 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D NsoK4_07780 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D NsoK4_00630 rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D NsoK4_01170 NUDIX domain-containing protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] D NsoK4_08785 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D NsoK4_08395 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D NsoK4_00110 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D NsoK4_00105 helix-turn-helix domain-containing protein K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D NsoK4_06110 adenylate/guanylate cyclase domain-containing protein K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D NsoK4_04115 adenylate/guanylate cyclase domain-containing protein K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D NsoK4_01155 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D NsoK4_08425 adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2] D NsoK4_06535 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D NsoK4_00605 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3] D NsoK4_01370 metallophosphoesterase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D NsoK4_09080 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D NsoK4_08950 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] C 00240 Pyrimidine metabolism [PATH:nip00240] D NsoK4_02320 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D NsoK4_02315 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D NsoK4_09965 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D NsoK4_09960 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D NsoK4_01305 dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D NsoK4_01310 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D NsoK4_07390 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D NsoK4_01165 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D NsoK4_09870 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D NsoK4_07780 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D NsoK4_01170 NUDIX domain-containing protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] D NsoK4_04790 pyrG; CTP synthase (glutamine hydrolyzing) K01937 pyrG; CTP synthase [EC:6.3.4.2] D NsoK4_06525 cytidylate kinase family protein K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D NsoK4_00105 helix-turn-helix domain-containing protein K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D NsoK4_00110 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D NsoK4_03030 dCMP deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12] D NsoK4_09860 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D NsoK4_07845 dihydroorotase family protein K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:nip00250] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_01000 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D NsoK4_03145 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D NsoK4_08055 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D NsoK4_01680 aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1] D NsoK4_01605 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D NsoK4_07540 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D NsoK4_01155 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D NsoK4_01005 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D NsoK4_09965 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D NsoK4_09960 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D NsoK4_01505 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D NsoK4_06780 aldehyde dehydrogenase family protein K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_02320 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D NsoK4_02315 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D NsoK4_03710 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D NsoK4_07145 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D NsoK4_03720 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:nip00260] D NsoK4_09600 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_07960 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_08465 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D NsoK4_04910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D NsoK4_09005 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D NsoK4_00355 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D NsoK4_03980 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D NsoK4_09330 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D NsoK4_02210 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D NsoK4_08035 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D NsoK4_05665 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D NsoK4_01690 D-2-hydroxyacid dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D NsoK4_05070 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D NsoK4_03935 pyridoxal phosphate-dependent aminotransferase family protein K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D NsoK4_04105 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D NsoK4_04750 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D NsoK4_04745 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D NsoK4_06440 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D NsoK4_06445 ectA; diaminobutyrate acetyltransferase K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178] D NsoK4_06435 ectoine synthase K06720 ectC; L-ectoine synthase [EC:4.2.1.108] D NsoK4_06430 thpD; ectoine hydroxylase K10674 ectD; ectoine hydroxylase [EC:1.14.11.55] C 00270 Cysteine and methionine metabolism [PATH:nip00270] D NsoK4_00710 pyridoxal-phosphate dependent enzyme K01738 cysK; cysteine synthase [EC:2.5.1.47] D NsoK4_01640 dihydropteroate synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_01635 homocysteine S-methyltransferase family protein K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_08700 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D NsoK4_01250 S-methyl-5'-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D NsoK4_08280 mtnA; S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D NsoK4_02940 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D NsoK4_09600 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_07960 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_08465 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D NsoK4_04910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D NsoK4_07615 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07970 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_09920 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_05015 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_06205 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_09485 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_07075 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D NsoK4_05050 cysteine synthase family protein K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] D NsoK4_01690 D-2-hydroxyacid dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:nip00280] D NsoK4_07615 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07970 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_03000 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D NsoK4_02975 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D NsoK4_02995 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D NsoK4_05190 NAD(P)-dependent oxidoreductase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_03960 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:nip00290] D NsoK4_04105 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D NsoK4_06305 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06315 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06300 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_06310 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D NsoK4_02380 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D NsoK4_02365 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_06400 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_02370 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D NsoK4_02965 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D NsoK4_04425 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D NsoK4_07615 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07970 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_08055 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D NsoK4_02375 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:nip00300] D NsoK4_04910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D NsoK4_09600 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_07960 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_08465 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D NsoK4_01600 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW D NsoK4_01565 lysX; lysine biosynthesis protein LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43] D NsoK4_01595 lysX; lysine biosynthesis protein LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43] D NsoK4_01585 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19] D NsoK4_01590 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106] D NsoK4_01580 aspartate aminotransferase family protein K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D NsoK4_01560 M20/M25/M40 family metallo-hydrolase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132] C 00310 Lysine degradation [PATH:nip00310] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_06375 FAD-dependent oxidoreductase K15736 lhgO; (S)-2-hydroxyglutarate dehydrogenase [EC:1.1.5.13] C 00220 Arginine biosynthesis [PATH:nip00220] D NsoK4_06565 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D NsoK4_01605 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D NsoK4_07540 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D NsoK4_03710 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_02320 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D NsoK4_02315 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D NsoK4_01505 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08055 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D NsoK4_01600 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW D NsoK4_01585 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19] D NsoK4_01590 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106] D NsoK4_01580 aspartate aminotransferase family protein K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D NsoK4_01560 M20/M25/M40 family metallo-hydrolase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132] C 00330 Arginine and proline metabolism [PATH:nip00330] D NsoK4_07815 creatininase family protein K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10] D NsoK4_04350 methylhydantoinase K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14] D NsoK4_02045 pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19] D NsoK4_03245 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D NsoK4_06785 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D NsoK4_06775 proline dehydrogenase family protein K00318 PRODH; proline dehydrogenase [EC:1.5.5.2] D NsoK4_06780 aldehyde dehydrogenase family protein K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:nip00340] D NsoK4_08320 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D NsoK4_00345 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D NsoK4_08290 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D NsoK4_08295 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D NsoK4_08285 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D NsoK4_08300 hisB; imidazoleglycerol-phosphate dehydratase HisB K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D NsoK4_08315 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D NsoK4_05095 egtD; L-histidine N(alpha)-methyltransferase K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44] C 00350 Tyrosine metabolism [PATH:nip00350] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00360 Phenylalanine metabolism [PATH:nip00360] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D NsoK4_05925 non-heme iron oxygenase ferredoxin subunit K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component D NsoK4_07235 non-heme iron oxygenase ferredoxin subunit K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component C 00380 Tryptophan metabolism D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:nip00400] D NsoK4_05575 class I fructose-bisphosphate aldolase family protein K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D NsoK4_05580 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24] D NsoK4_05585 aroD; type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D NsoK4_05595 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D NsoK4_05600 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D NsoK4_05605 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D NsoK4_04725 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D NsoK4_04730 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D NsoK4_04735 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D NsoK4_04740 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D NsoK4_04750 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D NsoK4_04745 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D NsoK4_05615 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D NsoK4_08365 pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:nip00410] D NsoK4_09795 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D NsoK4_07845 dihydroorotase family protein K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2] C 00430 Taurine and hypotaurine metabolism [PATH:nip00430] D NsoK4_03200 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D NsoK4_01505 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:nip00450] D NsoK4_01640 dihydropteroate synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_01635 homocysteine S-methyltransferase family protein K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_09545 aminotransferase class V-fold PLP-dependent enzyme K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D NsoK4_05920 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D NsoK4_05035 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D NsoK4_08950 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D NsoK4_02945 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:nip00460] D NsoK4_03200 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D NsoK4_09330 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:nip00470] D NsoK4_03710 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D NsoK4_08890 aspartate/glutamate racemase family protein K01776 murI; glutamate racemase [EC:5.1.1.3] C 00480 Glutathione metabolism [PATH:nip00480] D NsoK4_03200 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D NsoK4_07335 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:nip00542] D NsoK4_07640 UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis [PATH:nip00552] D NsoK4_07640 UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:nip00543] D NsoK4_07640 UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:nip00730] D NsoK4_05625 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D NsoK4_05640 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D NsoK4_07060 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D NsoK4_05025 thiazole biosynthesis protein K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D NsoK4_01045 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D NsoK4_06535 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:nip00740] D NsoK4_00190 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29] D NsoK4_00200 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D NsoK4_00180 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D NsoK4_00185 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D NsoK4_00175 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D NsoK4_01540 CTP-dependent riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D NsoK4_01550 FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2] D NsoK4_09700 bluB; 5,6-dimethylbenzimidazole synthase K04719 bluB; 5,6-dimethylbenzimidazole synthase [EC:1.13.11.79] D NsoK4_09810 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D NsoK4_03665 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:nip00750] D NsoK4_00355 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D NsoK4_03980 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D NsoK4_00950 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D NsoK4_00955 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:nip00760] D NsoK4_01805 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D NsoK4_01810 nadA; quinolinate synthase NadA K03517 nadA; quinolinate synthase [EC:2.5.1.72] D NsoK4_01820 nadC; carboxylating nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D NsoK4_09725 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D NsoK4_02960 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D NsoK4_02930 NAD+ synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D NsoK4_09415 NAD-dependent deacylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D NsoK4_03270 NAD(+)/NADH kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D NsoK4_06210 NAD(+)/NADH kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:nip00770] D NsoK4_02365 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_06400 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D NsoK4_02370 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D NsoK4_02965 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D NsoK4_04425 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D NsoK4_09790 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D NsoK4_09800 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D NsoK4_09795 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D NsoK4_09785 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D NsoK4_00865 pantetheine-phosphate adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D NsoK4_01840 GTP-dependent dephospho-CoA kinase family protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D NsoK4_07615 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07970 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07845 dihydroorotase family protein K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2] C 00780 Biotin metabolism [PATH:nip00780] D NsoK4_08270 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D NsoK4_03945 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D NsoK4_03950 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D NsoK4_03940 bioB; biotin synthase BioB K01012 bioB; biotin synthase [EC:2.8.1.6] D NsoK4_02870 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism C 00790 Folate biosynthesis [PATH:nip00790] D NsoK4_09020 folE; GTP cyclohydrolase I FolE K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D NsoK4_08380 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D NsoK4_00990 6-carboxytetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D NsoK4_00995 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D NsoK4_09025 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D NsoK4_09010 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D NsoK4_08385 DUF115 domain-containing protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] C 00670 One carbon pool by folate [PATH:nip00670] D NsoK4_02170 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D NsoK4_09330 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D NsoK4_02185 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D NsoK4_01640 dihydropteroate synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_01635 homocysteine S-methyltransferase family protein K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_07810 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D NsoK4_02165 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:nip00860] D NsoK4_07220 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D NsoK4_05830 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D NsoK4_07520 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D NsoK4_02760 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D NsoK4_05960 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D NsoK4_05835 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D NsoK4_05955 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D NsoK4_05945 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D NsoK4_05950 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D NsoK4_05825 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D NsoK4_05820 Lrp/AsnC family transcriptional regulator K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111] D NsoK4_04830 radical SAM protein K22226 ahbC; Fe-coproporphyrin III synthase D NsoK4_01880 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08475 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08720 sirohydrochlorin cobaltochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] D NsoK4_08900 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D NsoK4_09610 cobJ; precorrin-3B C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D NsoK4_08895 cobM; precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D NsoK4_08715 cobalamin biosynthesis protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D NsoK4_08710 cobalt-precorrin-5B (C(1))-methyltransferase K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D NsoK4_08905 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D NsoK4_09270 cbiE; precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D NsoK4_08725 precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D NsoK4_08730 cobyrinate a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D NsoK4_04155 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D NsoK4_08735 cobO; cob(I)yrinic acid a,c-diamide adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D NsoK4_08455 cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D NsoK4_08450 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D NsoK4_08440 NTP transferase domain-containing protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D NsoK4_08445 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D NsoK4_08460 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:nip00130] D NsoK4_05565 menaquinone biosynthesis decarboxylase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98] D NsoK4_03665 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D NsoK4_01490 class I SAM-dependent methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D NsoK4_03125 prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D NsoK4_03450 CofH family radical SAM protein K18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120] D NsoK4_05570 mqnC; dehypoxanthine futalosine cyclase K11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1] D NsoK4_03475 ABC transporter substrate-binding protein K11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:nip00900] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_03960 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D NsoK4_08325 hydroxymethylglutaryl-CoA reductase, degradative K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D NsoK4_07200 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D NsoK4_07205 isopentenyl phosphate kinase family protein K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D NsoK4_08935 aconitase X catalytic domain-containing protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182] D NsoK4_08930 DUF126 domain-containing protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D NsoK4_00285 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126] D NsoK4_03665 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D NsoK4_07210 idi; isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D NsoK4_07215 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D NsoK4_07410 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D NsoK4_01175 uppS; di-trans,poly-cis-decaprenylcistransferase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D NsoK4_07315 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D NsoK4_07320 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:nip00523] D NsoK4_00445 GDP-mannose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D NsoK4_00395 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D NsoK4_00445 GDP-mannose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:nip00261] D NsoK4_08950 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4] D NsoK4_09600 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_07960 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D NsoK4_08465 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:nip00521] D NsoK4_07800 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D NsoK4_05115 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D NsoK4_07505 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D NsoK4_00445 GDP-mannose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D NsoK4_00395 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis D NsoK4_00445 GDP-mannose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:nip00401] D NsoK4_05615 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D NsoK4_04725 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D NsoK4_04730 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D NsoK4_08270 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites D NsoK4_08700 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:nip00362] D NsoK4_00075 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:nip00627] D NsoK4_08610 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D NsoK4_03665 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation [PATH:nip00364] D NsoK4_05465 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] C 00625 Chloroalkane and chloroalkene degradation [PATH:nip00625] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:nip00361] D NsoK4_05465 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] C 00623 Toluene degradation [PATH:nip00623] D NsoK4_05465 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] C 00622 Xylene degradation D NsoK4_00075 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D NsoK4_00075 4-oxalocrotonate tautomerase family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation [PATH:nip00626] D NsoK4_01955 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D NsoK4_05760 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:nip03020] D NsoK4_07020 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D NsoK4_07015 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D NsoK4_06275 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D NsoK4_09585 hypothetical protein K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D NsoK4_01830 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D NsoK4_07025 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D NsoK4_07180 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D NsoK4_02680 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D NsoK4_03160 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 C 03022 Basal transcription factors [PATH:nip03022] D NsoK4_09105 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_09225 transcription initiation factor TFIIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_02565 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_02855 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_04585 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05245 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05790 transcription factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05865 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_06470 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_06790 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_00700 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_05320 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_00230 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:nip03010] D NsoK4_07190 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D NsoK4_03860 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D NsoK4_07140 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D NsoK4_06555 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D NsoK4_06980 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D NsoK4_03815 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D NsoK4_06290 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D NsoK4_02675 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D NsoK4_01035 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D NsoK4_06985 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D NsoK4_07135 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D NsoK4_03820 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D NsoK4_00755 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D NsoK4_03845 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D NsoK4_03870 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D NsoK4_00735 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D NsoK4_03830 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D NsoK4_08765 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D NsoK4_05775 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D NsoK4_01110 hypothetical protein K02962 RP-S17e; small subunit ribosomal protein S17e D NsoK4_00135 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D NsoK4_03170 MarR family transcriptional regulator K02975 RP-S25e; small subunit ribosomal protein S25e D NsoK4_03260 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e D NsoK4_08435 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D NsoK4_05680 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D NsoK4_07790 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D NsoK4_01320 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e D NsoK4_06685 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D NsoK4_08615 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D NsoK4_03885 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D NsoK4_03825 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D NsoK4_03810 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D NsoK4_06690 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D NsoK4_06625 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D NsoK4_06835 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D NsoK4_06285 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D NsoK4_03840 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D NsoK4_06545 uL15 family ribosomal protein K02876 RP-L15; large subunit ribosomal protein L15 D NsoK4_06560 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D NsoK4_03865 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D NsoK4_03875 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D NsoK4_03835 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D NsoK4_03855 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D NsoK4_06550 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D NsoK4_03880 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D NsoK4_07795 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D NsoK4_06160 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D NsoK4_01745 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D NsoK4_06280 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D NsoK4_06600 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D NsoK4_01340 50S ribosomal protein L21 K02889 RP-L21e; large subunit ribosomal protein L21e D NsoK4_07785 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D NsoK4_06995 ribosomal L7Ae/L30e/S12e/Gadd45 family protein K02908 RP-L30e; large subunit ribosomal protein L30e D NsoK4_06595 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D NsoK4_07825 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D NsoK4_06235 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D NsoK4_01655 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D NsoK4_02150 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D NsoK4_08430 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e C 00970 Aminoacyl-tRNA biosynthesis [PATH:nip00970] D NsoK4_07220 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D NsoK4_04305 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D NsoK4_04300 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D NsoK4_04310 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D NsoK4_08625 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D NsoK4_08630 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D NsoK4_06855 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D NsoK4_02395 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_04315 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_08810 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D NsoK4_03240 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D NsoK4_00740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D NsoK4_02925 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D NsoK4_02945 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D NsoK4_00985 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D NsoK4_06860 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D NsoK4_02125 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D NsoK4_05400 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D NsoK4_04960 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D NsoK4_05085 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D NsoK4_07685 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D NsoK4_00890 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D NsoK4_00895 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D NsoK4_09615 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D NsoK4_00885 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:nip03060] D NsoK4_06540 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D NsoK4_05700 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D NsoK4_06570 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D NsoK4_06615 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D NsoK4_05780 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19 D NsoK4_01475 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03675 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03680 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC D NsoK4_07875 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:nip04122] D NsoK4_07060 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D NsoK4_09920 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_05015 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_06205 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D NsoK4_05055 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D NsoK4_00360 ThiF family adenylyltransferase K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D NsoK4_01870 M67 family metallopeptidase K21140 mec; [CysO sulfur-carrier protein]-S-L-cysteine hydrolase [EC:3.13.1.6] C 03050 Proteasome [PATH:nip03050] D NsoK4_01495 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_03895 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_09745 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D NsoK4_04920 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:nip03018] D NsoK4_08360 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4 D NsoK4_06250 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D NsoK4_06240 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42 D NsoK4_06245 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D NsoK4_02020 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D NsoK4_08645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK B B 09124 Replication and repair C 03030 DNA replication [PATH:nip03030] D NsoK4_01535 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D NsoK4_07900 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D NsoK4_01290 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D NsoK4_03025 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D NsoK4_09290 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D NsoK4_09325 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D NsoK4_07650 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D NsoK4_08795 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102] D NsoK4_08800 DNA primase K18882 priL; DNA primase large subunit D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_07660 replication factor C small subunit K04801 rfcS; replication factor C small subunit D NsoK4_07495 AAA family ATPase K04800 rfcL; replication factor C large subunit D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:nip03410] D NsoK4_00580 DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D NsoK4_08940 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D NsoK4_02425 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D NsoK4_05455 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D NsoK4_02430 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D NsoK4_07700 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D NsoK4_08805 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D NsoK4_00750 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03420 Nucleotide excision repair [PATH:nip03420] D NsoK4_02245 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A D NsoK4_02240 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B D NsoK4_02250 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D NsoK4_03160 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D NsoK4_06220 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:nip03430] D NsoK4_00750 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D NsoK4_00800 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination [PATH:nip03440] D NsoK4_00750 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D NsoK4_08690 recombinase RecA K04482 RAD51; DNA repair protein RAD51 C 03450 Non-homologous end-joining D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D NsoK4_01825 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D NsoK4_06620 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:nip02010] D NsoK4_01610 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D NsoK4_01620 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D NsoK4_01615 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D NsoK4_00015 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein D NsoK4_00025 metal ABC transporter permease K09816 znuB; zinc transport system permease protein D NsoK4_00020 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D NsoK4_00475 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein D NsoK4_00470 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D NsoK4_09820 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein D NsoK4_09825 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:nip03070] D NsoK4_06540 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D NsoK4_06570 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D NsoK4_05700 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D NsoK4_01475 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03675 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03680 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC D NsoK4_00260 type VI secretion system tube protein Hcp K11903 hcp; type VI secretion system secreted protein Hcp B B 09132 Signal transduction C 02020 Two-component system [PATH:nip02020] D NsoK4_05755 response regulator K07775 resD; two-component system, OmpR family, response regulator ResD D NsoK4_00150 CoA ester lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D NsoK4_09130 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_09525 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_00520 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_00680 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_01480 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_02580 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_02755 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_00160 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_00835 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_02455 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04570 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04810 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_06500 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_07990 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_00560 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D NsoK4_08535 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:nip02024] D NsoK4_04725 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D NsoK4_04730 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D NsoK4_02355 lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase K08321 lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [EC:2.3.1.245] D NsoK4_05280 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D NsoK4_03330 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein D NsoK4_03325 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D NsoK4_02405 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D NsoK4_05100 ABC transporter ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D NsoK4_06540 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D NsoK4_06570 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D NsoK4_05700 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis D NsoK4_00160 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_00835 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_02455 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04570 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04810 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_06500 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_07990 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:nip04980] D NsoK4_04155 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D NsoK4_02990 meaB; methylmalonyl Co-A mutase-associated GTPase MeaB K07588 MMAA; GTPase [EC:3.6.5.-] D NsoK4_01640 dihydropteroate synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D NsoK4_01635 homocysteine S-methyltransferase family protein K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:nip01000] C 01001 Protein kinases [BR:nip01001] D NsoK4_00625 Kae1-associated serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D NsoK4_01205 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] C 01009 Protein phosphatases and associated proteins [BR:nip01009] D NsoK4_01195 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D NsoK4_02940 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D NsoK4_05070 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:nip01002] D NsoK4_04255 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D NsoK4_08785 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D NsoK4_08395 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D NsoK4_03720 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D NsoK4_07145 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D NsoK4_01000 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D NsoK4_03145 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D NsoK4_02980 M1 family metallopeptidase K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-] D NsoK4_02060 M3 family oligoendopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D NsoK4_07335 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D NsoK4_05305 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D NsoK4_06585 S8 family serine peptidase K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-] D NsoK4_07875 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89] D NsoK4_00070 rhomboid family intramembrane serine protease K07059 K07059; rhomboid family protein D NsoK4_01495 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_03895 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_09745 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D NsoK4_04920 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D NsoK4_03200 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D NsoK4_05360 TldD/PmbA family protein K03592 pmbA; PmbA protein D NsoK4_02435 TldD/PmbA family protein K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:nip01003] D NsoK4_08545 hypothetical protein K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18] D NsoK4_08880 glycosyltransferase family 2 protein K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83] D NsoK4_07640 UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01005 Lipopolysaccharide biosynthesis proteins [BR:nip01005] D NsoK4_07640 UDP-N-acetylglucosamine-1-phosphate transferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:nip01011] D NsoK4_08890 aspartate/glutamate racemase family protein K01776 murI; glutamate racemase [EC:5.1.1.3] C 01004 Lipid biosynthesis proteins [BR:nip01004] D NsoK4_08270 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D NsoK4_04290 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D NsoK4_04885 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:nip01006] D NsoK4_07215 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D NsoK4_07410 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D NsoK4_03125 prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D NsoK4_01880 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08475 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:nip01007] D NsoK4_05400 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D NsoK4_07220 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D NsoK4_09615 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D NsoK4_00885 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D NsoK4_02925 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D NsoK4_04960 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D NsoK4_02945 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D NsoK4_02125 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D NsoK4_00985 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D NsoK4_06860 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D NsoK4_02395 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_04315 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_07685 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D NsoK4_08810 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D NsoK4_00740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D NsoK4_05085 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D NsoK4_03240 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D NsoK4_06855 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D NsoK4_00890 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D NsoK4_00895 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D NsoK4_04285 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_05610 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D NsoK4_08055 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D NsoK4_08310 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D NsoK4_03935 pyridoxal phosphate-dependent aminotransferase family protein K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D NsoK4_01580 aspartate aminotransferase family protein K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D NsoK4_06440 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D NsoK4_03945 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D NsoK4_02760 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D NsoK4_05960 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D NsoK4_07615 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_07970 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D NsoK4_08860 DegT/DnrJ/EryC1/StrS family aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:nip03000] D NsoK4_00700 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_05320 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_06680 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D NsoK4_08470 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D NsoK4_05860 cobalamin-dependent protein K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator D NsoK4_07735 transcriptional repressor K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D NsoK4_05975 winged helix-turn-helix transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D NsoK4_08560 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D NsoK4_02465 transcriptional regulator K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator D NsoK4_02870 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D NsoK4_08555 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_02100 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_02295 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_03075 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_04190 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_04260 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D NsoK4_00010 CopG family ribbon-helix-helix protein K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D NsoK4_04615 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 03021 Transcription machinery [BR:nip03021] D NsoK4_03160 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D NsoK4_09105 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_09225 transcription initiation factor TFIIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_02565 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_02855 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_04585 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05245 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05790 transcription factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_05865 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_06470 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_06790 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D NsoK4_00700 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_05320 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D NsoK4_00230 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D NsoK4_01825 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D NsoK4_06620 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D NsoK4_09000 ATP/GTP-binding protein K24104 GPN; GPN-loop GTPase D NsoK4_06990 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA D NsoK4_07015 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D NsoK4_07020 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D NsoK4_06275 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D NsoK4_01830 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D NsoK4_07025 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D NsoK4_09585 hypothetical protein K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D NsoK4_07180 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D NsoK4_02680 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D NsoK4_09590 transcription factor S K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:nip03019] D NsoK4_01825 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D NsoK4_06620 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D NsoK4_08620 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_09240 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_04450 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_08580 pelota family protein K06965 PELO; protein pelota D NsoK4_04405 peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1 D NsoK4_04600 peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D NsoK4_02670 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D NsoK4_08360 exosome complex RNA-binding protein Csl4 K07573 CSL4; exosome complex component CSL4 D NsoK4_06250 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D NsoK4_06245 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D NsoK4_06240 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42 D NsoK4_02020 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D NsoK4_08645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK C 03041 Spliceosome C 03011 Ribosome [BR:nip03011] D NsoK4_00735 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D NsoK4_03830 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D NsoK4_08765 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D NsoK4_05775 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D NsoK4_01110 hypothetical protein K02962 RP-S17e; small subunit ribosomal protein S17e D NsoK4_00135 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D NsoK4_03170 MarR family transcriptional regulator K02975 RP-S25e; small subunit ribosomal protein S25e D NsoK4_03260 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e D NsoK4_08435 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D NsoK4_05680 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D NsoK4_07790 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D NsoK4_01320 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e D NsoK4_03880 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D NsoK4_07795 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D NsoK4_06160 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D NsoK4_01745 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D NsoK4_06280 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D NsoK4_06600 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D NsoK4_01340 50S ribosomal protein L21 K02889 RP-L21e; large subunit ribosomal protein L21e D NsoK4_07785 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D NsoK4_06995 ribosomal L7Ae/L30e/S12e/Gadd45 family protein K02908 RP-L30e; large subunit ribosomal protein L30e D NsoK4_06595 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D NsoK4_07825 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D NsoK4_06235 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D NsoK4_01655 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D NsoK4_02150 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D NsoK4_08430 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D NsoK4_07190 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D NsoK4_03860 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D NsoK4_07140 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D NsoK4_06555 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D NsoK4_06980 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D NsoK4_03815 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D NsoK4_06290 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D NsoK4_02675 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D NsoK4_01035 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D NsoK4_06985 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D NsoK4_07135 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D NsoK4_03820 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D NsoK4_00755 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D NsoK4_03845 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D NsoK4_03870 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D NsoK4_06685 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D NsoK4_08615 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D NsoK4_03885 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D NsoK4_03825 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D NsoK4_03810 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D NsoK4_06690 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D NsoK4_06625 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D NsoK4_06285 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D NsoK4_03840 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D NsoK4_06545 uL15 family ribosomal protein K02876 RP-L15; large subunit ribosomal protein L15 D NsoK4_06560 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D NsoK4_03865 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D NsoK4_03875 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D NsoK4_03835 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D NsoK4_03855 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D NsoK4_06550 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D NsoK4_06835 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 C 03009 Ribosome biogenesis [BR:nip03009] D NsoK4_01300 ribonucleotide-diphosphate reductase subunit beta K14564 NOP56; nucleolar protein 56 D NsoK4_08745 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D NsoK4_00120 ribosome biogenesis protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] D NsoK4_01210 RNA-binding protein K06961 KRR1; ribosomal RNA assembly protein D NsoK4_01205 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D NsoK4_00605 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3] D NsoK4_05285 DUF367 family protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157] D NsoK4_07350 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D NsoK4_03850 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D NsoK4_07680 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D NsoK4_06255 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1 D NsoK4_08620 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_09240 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_04450 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_01295 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein D NsoK4_07795 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D NsoK4_05785 hypothetical protein K07569 gar1; RNA-binding protein D NsoK4_06990 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA D NsoK4_01355 ribose ABC transporter permease K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D NsoK4_01280 RlmE family RNA methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D NsoK4_01335 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D NsoK4_07365 rimI; ribosomal protein S18-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D NsoK4_02020 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D NsoK4_00240 hflX; GTPase HflX K03665 hflX; GTPase D NsoK4_01125 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D NsoK4_00610 redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase D NsoK4_02895 redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:nip03016] D NsoK4_03850 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D NsoK4_00130 RNase P subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D NsoK4_09420 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D NsoK4_01020 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D NsoK4_07745 archease K24956 ZBTB8OS; protein archease D NsoK4_02670 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D NsoK4_07220 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D NsoK4_05085 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D NsoK4_02125 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D NsoK4_06860 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D NsoK4_02945 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D NsoK4_04960 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D NsoK4_06855 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D NsoK4_08810 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D NsoK4_03240 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D NsoK4_00740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D NsoK4_02925 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D NsoK4_00985 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D NsoK4_07685 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D NsoK4_00890 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D NsoK4_00895 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D NsoK4_09615 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D NsoK4_00885 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D NsoK4_06610 D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D NsoK4_02720 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D NsoK4_04410 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D NsoK4_01675 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D NsoK4_01285 tRNA (guanine-N1)-methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D NsoK4_07355 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D NsoK4_04940 tRNA (adenine-N1)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D NsoK4_00635 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D NsoK4_06520 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D NsoK4_01920 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D NsoK4_05695 pseudouridine synthase K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D NsoK4_07060 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D NsoK4_00625 Kae1-associated serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D NsoK4_00615 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] D NsoK4_05395 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311] D NsoK4_01125 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D NsoK4_01120 THUMP domain-containing protein K06963 TAN1; tRNA acetyltransferase TAN1 D NsoK4_09075 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D NsoK4_09390 cca; CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D NsoK4_02645 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D NsoK4_06155 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D NsoK4_09395 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D NsoK4_05400 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D NsoK4_02395 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_04315 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D NsoK4_00655 dusB; tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D NsoK4_09425 methyltransferase domain-containing protein K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D NsoK4_00235 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D NsoK4_05055 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D NsoK4_01530 erpA; iron-sulfur cluster insertion protein ErpA K13628 iscA; iron-sulfur cluster assembly protein D NsoK4_06230 CTAG/PCC1 family protein K09741 pcc1; KEOPS complex subunit Pcc1 D NsoK4_09010 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D NsoK4_00990 6-carboxytetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D NsoK4_09025 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D NsoK4_00600 tgtA; tRNA guanosine(15) transglycosylase TgtA K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D NsoK4_08340 DUF1743 domain-containing protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] C 03012 Translation factors [BR:nip03012] D NsoK4_04855 translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A D NsoK4_05740 eif1A; translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A D NsoK4_05255 translation initiation factor K03113 EIF1; translation initiation factor 1 D NsoK4_08740 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D NsoK4_01195 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D NsoK4_08760 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3 D NsoK4_05715 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A D NsoK4_07775 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B D NsoK4_07680 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D NsoK4_02670 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D NsoK4_01895 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta D NsoK4_03485 elongation factor EF-2 K03234 EEF2; elongation factor 2 D NsoK4_08345 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D NsoK4_05705 diphthine--ammonia ligase K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D NsoK4_04405 peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1 D NsoK4_04600 peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D NsoK4_01360 methyltransferase domain-containing protein K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D NsoK4_01910 peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:nip03110] D NsoK4_08645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D NsoK4_09335 TCP-1/cpn60 chaperonin family protein K22447 cct; archaeal chaperonin D NsoK4_08420 TCP-1/cpn60 chaperonin family protein K22447 cct; archaeal chaperonin D NsoK4_08640 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D NsoK4_08650 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE D NsoK4_09150 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D NsoK4_09160 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D NsoK4_09245 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D NsoK4_04950 Hsp20 family protein K13993 HSP20; HSP20 family protein D NsoK4_09855 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D NsoK4_06575 pfdA; prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit D NsoK4_06225 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit D NsoK4_06585 S8 family serine peptidase K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-] D NsoK4_09675 peptidylprolyl isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D NsoK4_09735 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D NsoK4_03050 peptidylprolyl isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] D NsoK4_07760 trxA; thioredoxin K03671 TXN; thioredoxin D NsoK4_07865 trxA; thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:nip04131] D NsoK4_07780 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D NsoK4_08620 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_09240 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_04450 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_08690 recombinase RecA K04482 RAD51; DNA repair protein RAD51 D NsoK4_06615 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D NsoK4_02670 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:nip04121] D NsoK4_02150 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D NsoK4_05680 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D NsoK4_01320 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e D NsoK4_08690 recombinase RecA K04482 RAD51; DNA repair protein RAD51 C 03051 Proteasome [BR:nip03051] D NsoK4_01495 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_03895 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D NsoK4_09745 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D NsoK4_04920 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03032 DNA replication proteins [BR:nip03032] D NsoK4_07900 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D NsoK4_08745 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D NsoK4_06220 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D NsoK4_01455 DNA topoisomerase I K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1] D NsoK4_01535 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D NsoK4_09295 AAA family ATPase K10725 cdc6A; archaeal cell division control protein 6 D NsoK4_07650 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D NsoK4_08795 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102] D NsoK4_08800 DNA primase K18882 priL; DNA primase large subunit D NsoK4_09350 DNA replication complex GINS family protein K09723 ginS; DNA replication factor GINS D NsoK4_07655 DNA replication complex GINS family protein K09723 ginS; DNA replication factor GINS D NsoK4_01290 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D NsoK4_03025 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D NsoK4_09325 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D NsoK4_09290 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D NsoK4_07495 AAA family ATPase K04800 rfcL; replication factor C large subunit D NsoK4_07660 replication factor C small subunit K04801 rfcS; replication factor C small subunit D NsoK4_00800 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D NsoK4_01220 DNA topoisomerase IV subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D NsoK4_01215 DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] C 03036 Chromosome and associated proteins [BR:nip03036] D NsoK4_03890 hypothetical protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-] D NsoK4_01100 NFYB/HAP3 family transcription factor subunit K24450 hmf; DNA-binding protein D NsoK4_05105 chromosome segregation protein SMC K03529 smc; chromosome segregation protein D NsoK4_05765 chromosome segregation protein ScpA K05896 scpA; segregation and condensation protein A D NsoK4_05770 scpB; SMC-Scp complex subunit ScpB K06024 scpB; segregation and condensation protein B D NsoK4_01670 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D NsoK4_04615 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D NsoK4_01835 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:nip03400] D NsoK4_06605 MGMT family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D NsoK4_02425 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D NsoK4_00580 DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D NsoK4_08940 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D NsoK4_09595 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D NsoK4_02655 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D NsoK4_03160 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 D NsoK4_06220 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D NsoK4_08690 recombinase RecA K04482 RAD51; DNA repair protein RAD51 D NsoK4_02430 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D NsoK4_07700 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D NsoK4_05455 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D NsoK4_08805 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D NsoK4_00750 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D NsoK4_02245 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A D NsoK4_02240 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B D NsoK4_02250 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D NsoK4_00800 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D NsoK4_01775 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 D NsoK4_01780 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 D NsoK4_03495 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D NsoK4_01325 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA D NsoK4_01785 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D NsoK4_01790 DNA double-strand break repair nuclease NurA K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-] D NsoK4_07645 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D NsoK4_05145 dinB; DNA polymerase IV K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7] D NsoK4_08685 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D NsoK4_00110 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D NsoK4_05155 hypothetical protein K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:nip03029] D NsoK4_00560 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D NsoK4_03850 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D NsoK4_09615 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D NsoK4_06860 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D NsoK4_08810 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D NsoK4_04960 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D NsoK4_04305 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D NsoK4_04300 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D NsoK4_04310 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D NsoK4_08645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D NsoK4_08650 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE D NsoK4_08640 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D NsoK4_07060 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D NsoK4_01835 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning D NsoK4_01880 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D NsoK4_08475 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:nip02000] D NsoK4_01610 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D NsoK4_01620 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D NsoK4_01615 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D NsoK4_05280 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D NsoK4_03330 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein D NsoK4_03325 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D NsoK4_02405 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D NsoK4_05100 ABC transporter ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D NsoK4_05160 cobalamin-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D NsoK4_00015 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein D NsoK4_00025 metal ABC transporter permease K09816 znuB; zinc transport system permease protein D NsoK4_00020 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D NsoK4_00475 ABC transporter permease K09690 wzm; homopolymeric O-antigen transport system permease protein D NsoK4_00470 ABC transporter ATP-binding protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D NsoK4_09820 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein D NsoK4_09825 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D NsoK4_08670 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D NsoK4_06010 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D NsoK4_08675 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D NsoK4_06015 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D NsoK4_05795 sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D NsoK4_05530 MIP family channel protein K09866 AQP4; aquaporin-4 D NsoK4_05965 aquaporin K06188 aqpZ; aquaporin Z D NsoK4_07255 two pore domain potassium channel family protein K10716 kch; voltage-gated potassium channel D NsoK4_09125 ammonium transporter K03320 amt; ammonium transporter, Amt family D NsoK4_09910 ammonium transporter K03320 amt; ammonium transporter, Amt family D NsoK4_09435 mechanosensitive ion channel K05802 mscK; potassium-dependent mechanosensitive channel D NsoK4_02600 mechanosensitive ion channel K05802 mscK; potassium-dependent mechanosensitive channel D NsoK4_03185 corA; magnesium/cobalt transporter CorA K03284 corA; magnesium transporter D NsoK4_07290 magnesium transporter CorA family protein K03284 corA; magnesium transporter D NsoK4_09215 CrcB family protein K06199 crcB; fluoride exporter D NsoK4_03190 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family D NsoK4_03975 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family D NsoK4_06715 ZIP family metal transporter K07238 TC.ZIP; zinc transporter, ZIP family D NsoK4_07115 divalent cation transporter K07238 TC.ZIP; zinc transporter, ZIP family D NsoK4_05365 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter D NsoK4_09090 cation:proton antiporter K03316 nhaP; Na+:H+ antiporter D NsoK4_06180 cation:proton antiporter K26735 KEA4_5_6; K+:H+ antiporter D NsoK4_02000 cation:proton antiporter K26730 napA; Na+:H+ antiporter D NsoK4_03235 cation:proton antiporter K26730 napA; Na+:H+ antiporter D NsoK4_05385 cation:proton antiporter K26730 napA; Na+:H+ antiporter D NsoK4_02615 CBS domain-containing protein K03498 trkH; trk/ktr system potassium uptake protein D NsoK4_03625 CBS domain-containing protein K03498 trkH; trk/ktr system potassium uptake protein D NsoK4_09490 VIT1/CCC1 transporter family protein K22736 VIT; vacuolar iron transporter family protein D NsoK4_04355 FTR1 family protein K07243 FTR; high-affinity iron transporter D NsoK4_03020 hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein D NsoK4_01850 sodium-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] D NsoK4_03930 sulfite exporter TauE/SafE family protein K06196 ccdA; cytochrome c-type biogenesis protein D NsoK4_07945 sulfite exporter TauE/SafE family protein K06196 ccdA; cytochrome c-type biogenesis protein D NsoK4_00030 CopD family protein K14166 ycnJ; copper transport protein C 02044 Secretion system [BR:nip02044] D NsoK4_03090 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI D NsoK4_04235 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI D NsoK4_03080 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ D NsoK4_03085 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ D NsoK4_04255 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D NsoK4_03030 dCMP deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12] D NsoK4_00260 type VI secretion system tube protein Hcp K11903 hcp; type VI secretion system secreted protein Hcp D NsoK4_06540 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D NsoK4_05700 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D NsoK4_06570 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D NsoK4_06615 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D NsoK4_05780 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19 D NsoK4_01475 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03675 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D NsoK4_03680 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:nip02042] D NsoK4_03190 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family D NsoK4_03975 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family C 02022 Two-component system [BR:nip02022] D NsoK4_05755 response regulator K07775 resD; two-component system, OmpR family, response regulator ResD D NsoK4_00160 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_00835 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_02455 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04570 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04810 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_06500 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_07990 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C 02035 Bacterial motility proteins [BR:nip02035] D NsoK4_00160 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_00835 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_02455 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04570 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_04810 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_06500 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_07990 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D NsoK4_03090 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI D NsoK4_04235 type II/IV secretion system ATPase subunit K07332 flaI; archaeal flagellar protein FlaI D NsoK4_03080 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ D NsoK4_03085 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ D NsoK4_04255 prepilin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:nip04812] D NsoK4_07195 MEMO1 family protein K06990 MEMO1; MEMO1 family protein D NsoK4_01670 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D NsoK4_04615 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:nip04147] D NsoK4_07185 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D NsoK4_05905 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D NsoK4_02670 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D NsoK4_03485 elongation factor EF-2 K03234 EEF2; elongation factor 2 D NsoK4_08645 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D NsoK4_04875 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D NsoK4_08375 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D NsoK4_05680 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D NsoK4_08620 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_09240 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_04450 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D NsoK4_02720 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D NsoK4_04410 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D NsoK4_00090 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_04060 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D NsoK4_02940 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D NsoK4_06535 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D NsoK4_01255 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D NsoK4_07540 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D NsoK4_01605 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D NsoK4_07845 dihydroorotase family protein K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2] D NsoK4_09345 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_09445 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D NsoK4_05835 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D NsoK4_00995 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D NsoK4_01690 D-2-hydroxyacid dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D NsoK4_03015 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:nip02048] D NsoK4_03495 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D NsoK4_09890 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D NsoK4_08105 type I restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D NsoK4_06865 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D NsoK4_08100 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D NsoK4_08110 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D NsoK4_06870 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D NsoK4_08115 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D NsoK4_00800 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D NsoK4_01470 site-specific DNA-methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D NsoK4_01670 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D NsoK4_07220 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D NsoK4_06215 PIN domain-containing protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] D NsoK4_07060 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes [BR:nip01504] D NsoK4_01915 lyase K18235 vgb; virginiamycin B lyase [EC:4.2.99.-] C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D NsoK4_00220 NAD-dependent succinate-semialdehyde dehydrogenase K18601 K18601; aldehyde dehydrogenase [EC:1.2.1.-] D NsoK4_02220 LLM class flavin-dependent oxidoreductase K14728 K14728; phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase [EC:1.2.-.-] D NsoK4_07400 iron-containing redox enzyme family protein K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11] D NsoK4_08040 npdG; NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D NsoK4_02805 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D NsoK4_04905 msrB; peptide-methionine (R)-S-oxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D NsoK4_05535 bcp; thioredoxin-dependent thiol peroxidase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D NsoK4_07470 redoxin domain-containing protein K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25] D NsoK4_05440 ferritin K02217 ftnA; ferritin [EC:1.16.3.2] D NsoK4_07510 ferredoxin--NADP reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D NsoK4_07600 ferredoxin--NADP reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D NsoK4_03345 arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D NsoK4_05970 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D NsoK4_08550 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D NsoK4_09560 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D NsoK4_01555 dph5; diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D NsoK4_03180 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D NsoK4_05120 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D NsoK4_07080 larB; nickel pincer cofactor biosynthesis protein LarB K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D NsoK4_03255 CDP-alcohol phosphatidyltransferase family protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D NsoK4_01105 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D NsoK4_06920 thermonuclease family protein K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D NsoK4_00080 carbon-nitrogen hydrolase family protein K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D NsoK4_04935 NAD(P)H-hydrate dehydratase K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136] D NsoK4_07065 larE; ATP-dependent sacrificial sulfur transferase LarE K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D NsoK4_07070 larC; nickel pincer cofactor biosynthesis protein LarC K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D NsoK4_07160 NAD(P)H-hydrate epimerase K17759 NAXE; NAD(P)H-hydrate epimerase [EC:5.1.99.6] D NsoK4_09720 rtcA; RNA 3'-phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D NsoK4_05915 iron-sulfur cluster assembly scaffold protein K04488 iscU; nitrogen fixation protein NifU and related proteins D NsoK4_04225 VWA domain-containing protein K02448 norD; nitric oxide reductase NorD protein D NsoK4_00720 MoxR family ATPase K04748 norQ; nitric oxide reductase NorQ protein D NsoK4_04220 AAA family ATPase K04748 norQ; nitric oxide reductase NorQ protein C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D NsoK4_08990 flippase-like domain-containing protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism C 99988 Secondary metabolism D NsoK4_02490 NAD(P)H-dependent oxidoreductase K19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone) C 99999 Others D NsoK4_04925 DoxX family protein K15977 K15977; putative oxidoreductase B B 09192 Unclassified: genetic information processing C 99973 Transcription D NsoK4_03155 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D NsoK4_04590 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D NsoK4_07585 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D NsoK4_05735 cold-shock protein K03704 cspA; cold shock protein D NsoK4_08695 ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein D NsoK4_07010 ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein D NsoK4_07820 RNA-binding protein K04796 RUXX; small nuclear ribonucleoprotein C 99974 Translation D NsoK4_01350 DUF655 domain-containing protein K07572 K07572; putative nucleotide binding protein D NsoK4_00585 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor D NsoK4_02190 exonuclease K07577 K07577; putative mRNA 3-end processing factor D NsoK4_01900 RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein D NsoK4_00730 exosome protein K07581 K07581; RNA-binding protein C 99975 Protein processing D NsoK4_00250 queuine tRNA-ribosyltransferase K07398 K07398; conserved protein with predicted RNA binding PUA domain C 99976 Replication and repair D NsoK4_02285 single-stranded DNA exonuclease RecJ K07463 K07463; archaea-specific RecJ-like exonuclease D NsoK4_07170 RNA-binding protein K07477 K07477; translin D NsoK4_00085 topoisomerase DNA-binding C4 zinc finger domain-containing protein K07479 yrdD; putative DNA topoisomerase D NsoK4_06880 IS1/IS6 family transposase K07498 K07498; putative transposase C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D NsoK4_05990 inorganic phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family C 99978 Cell growth C 99993 Cell motility D NsoK4_03115 hypothetical protein K23255 pilA; archaeal type IV pilus assembly protein PilA C 99995 Signaling proteins D NsoK4_09385 serine/threonine protein kinase K07176 K07176; putative serine/threonine protein kinase D NsoK4_00140 DNA-binding protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D NsoK4_08585 divalent-cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein B B 09194 Poorly characterized C 99996 General function prediction only D NsoK4_02460 tadA; Flp pilus assembly complex ATPase component TadA K06865 K06865; ATPase D NsoK4_01465 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein D NsoK4_04660 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein D NsoK4_05325 tRNA-binding protein K06878 K06878; tRNA-binding protein D NsoK4_01330 HAD family phosphatase K07025 K07025; putative hydrolase of the HAD superfamily D NsoK4_05930 sufD; Fe-S cluster assembly protein SufD K09014 sufB; Fe-S cluster assembly protein SufB D NsoK4_05935 sufB; Fe-S cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D NsoK4_04555 hypothetical protein K07100 K07100; putative phosphoribosyl transferase D NsoK4_05260 hypothetical protein K07143 K07143; UPF0148 protein D NsoK4_01180 DUF373 family protein K08975 K08975; putative membrane protein D NsoK4_05270 DUF2070 family protein K08979 K08979; putative membrane protein C 99997 Function unknown D NsoK4_09165 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D NsoK4_05125 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D NsoK4_05375 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D NsoK4_05480 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D NsoK4_09865 HD domain-containing protein K06885 K06885; uncharacterized protein D NsoK4_08240 HD domain-containing protein K06885 K06885; uncharacterized protein D NsoK4_01965 thioredoxin domain-containing protein K06888 K06888; uncharacterized protein D NsoK4_02885 CoA-binding protein K06929 K06929; uncharacterized protein D NsoK4_05745 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein D NsoK4_06965 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein D NsoK4_05870 HD domain-containing protein K06950 K06950; uncharacterized protein D NsoK4_02325 metallophosphoesterase K06953 K06953; uncharacterized protein D NsoK4_02235 pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein D NsoK4_05415 pyridoxamine 5'-phosphate oxidase family protein K07006 K07006; uncharacterized protein D NsoK4_08405 pyridoxamine 5'-phosphate oxidase family protein K07006 K07006; uncharacterized protein D NsoK4_09750 beta-CASP ribonuclease aCPSF1 K07041 K07041; uncharacterized protein D NsoK4_03210 amidohydrolase family protein K07045 K07045; uncharacterized protein D NsoK4_00095 OB-fold domain-containing protein K07068 K07068; uncharacterized protein D NsoK4_04055 hypothetical protein K07068 K07068; uncharacterized protein D NsoK4_05985 sodium-dependent bicarbonate transport family permease K07086 K07086; uncharacterized protein D NsoK4_02485 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein D NsoK4_02845 phosphoribosyltransferase K07101 K07101; uncharacterized protein D NsoK4_03150 transcriptional regulator K07108 K07108; uncharacterized protein D NsoK4_08980 SDR family oxidoreductase K07124 K07124; uncharacterized protein D NsoK4_08755 twitching motility protein PilT K07158 K07158; uncharacterized protein D NsoK4_04650 PAC2 family protein K07159 K07159; uncharacterized protein D NsoK4_02475 DUF192 domain-containing protein K09005 K09005; uncharacterized protein D NsoK4_08790 UPF0182 family protein K09118 K09118; uncharacterized protein D NsoK4_05200 DUF99 family protein K09120 K09120; uncharacterized protein D NsoK4_08920 Mut7-C RNAse domain-containing protein K09122 K09122; uncharacterized protein D NsoK4_05800 DUF167 domain-containing protein K09131 K09131; uncharacterized protein D NsoK4_08925 TIGR00296 family protein K09141 K09141; uncharacterized protein D NsoK4_01865 hypothetical protein K09143 K09143; uncharacterized protein D NsoK4_01200 DUF424 domain-containing protein K09148 K09148; uncharacterized protein D NsoK4_02905 DUF432 domain-containing protein K09149 K09149; uncharacterized protein D NsoK4_09755 cell division protein SepF K09152 K09152; uncharacterized protein D NsoK4_08235 hypothetical protein K09388 K09388; uncharacterized protein D NsoK4_07240 UPF0147 family protein K09721 K09721; uncharacterized protein D NsoK4_08660 DUF354 domain-containing protein K09726 K09726; uncharacterized protein D NsoK4_09405 hypothetical protein K09736 K09736; uncharacterized protein D NsoK4_03900 DUF371 domain-containing protein K09738 K09738; uncharacterized protein D NsoK4_05670 DUF309 domain-containing protein K09763 K09763; uncharacterized protein D NsoK4_06145 SIMPL domain-containing protein K09807 K09807; uncharacterized protein D NsoK4_07725 SIMPL domain-containing protein K09807 K09807; uncharacterized protein D NsoK4_02650 DUF47 family protein K07220 K07220; uncharacterized protein D NsoK4_05995 DUF47 domain-containing protein K07220 K07220; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2024