+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Nymphalis io (European peacock)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 126781074 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 126781299 mRNA-capping enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 126773162 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 126773968 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 126778038 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 126774904 RNA guanine-N7 methyltransferase activating subunit K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 126773209 nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 126775494 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 126780107 cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 126776779 cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 126776193 protein CLP1 homolog K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 126777493 cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 126776093 probable cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 126774963 cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 126774332 cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 126771708 pre-mRNA 3' end processing protein WDR33 K15542 PFS2; polyadenylation factor subunit 2
E 126780891 WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 126769692 serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 126775562 serine/threonine-protein phosphatase alpha-2 isoform isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 126768219 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 126779553 cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 126772699 cleavage stimulation factor subunit 2 tau variant isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 126778819 protein suppressor of forked K14408 CSTF3; cleavage stimulation factor subunit 3
E 126769440 symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 126781417 small nuclear ribonucleoprotein-associated protein B K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 126775378 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 126774107 probable small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 126774500 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 126777934 probable small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 126778325 U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 126776093 probable cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 126774963 cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 126772699 cleavage stimulation factor subunit 2 tau variant isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 126769440 symplekin K06100 SYMPK; symplekin
E 126773577 histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
D DRB sensitivity inducing factor (DSIF) complex
E 126773698 transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 126781201 transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 126777189 N6-adenosine-methyltransferase subunit METTL3 isoform X1 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 126771755 N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 126775152 DNA N6-methyl methyltransferase K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 126773980 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase isoform X1 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 126771958 pre-mRNA-splicing regulator female-lethal(2)D K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 126774282 protein virilizer isoform X1 K22910 VIRMA; protein virilizer
E 126774825 RNA-binding protein spenito K13190 RBM15; RNA-binding protein 15
E 126768525 E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 126778471 poly(A) polymerase type 3 isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 126773370 poly(A) RNA polymerase gld-2 homolog A-like isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 126779514 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
E 126770358 TAR DNA-binding protein 43-like K23600 TARDBP; TAR DNA-binding protein 43
E 126773179 TAR DNA-binding protein 43-like K23600 TARDBP; TAR DNA-binding protein 43
E 126774511 TAR DNA-binding protein 43-like K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 126779576 DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 126774233 methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 126779083 serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 126779018 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 126779019 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 126779022 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 126779023 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 126779146 RNA-binding protein 8A-like isoform X1 K12876 RBM8A; RNA-binding protein 8A
E 126773966 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 126773971 THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 126775223 ATP-dependent RNA helicase WM6 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 126776213 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 126776339 coiled-coil domain-containing protein 174 isoform X1 K25178 CCDC174; coiled-coil domain-containing protein 174
E 126772277 histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 126775835 pinin K13114 PNN; pinin
E 126773938 RNA-binding protein with serine-rich domain 1-A-like K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 126768598 serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 126774459 THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 126781800 THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 126778238 THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 126773971 THO complex subunit 4 isoform X1 K12881 THOC4; THO complex subunit 4
E 126773892 THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 126770216 THO complex subunit 6 K13175 THOC6; THO complex subunit 6
E 126772417 THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 126768976 PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 126779655 uncharacterized protein LOC126779655 isoform X1 K10840 CETN2; centrin-2
D Nuclear pore complex
E 126774138 nucleoprotein TPR-like isoform X1 K09291 TPR; nucleoprotein TPR
E 126777093 protein Rae1 K14298 RAE1; mRNA export factor
E 126775774 protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 126770935 nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 126771347 nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 126781590 nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 126779509 probable nucleoporin Nup54 K14308 NUP54; nuclear pore complex protein Nup54
E 126775526 nucleoporin 88 K14318 NUP88; nuclear pore complex protein Nup88
E 126781409 nuclear pore complex protein Nup93-like K14309 NUP93; nuclear pore complex protein Nup93
E 126772317 nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 126776191 nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 126768535 nucleoporin Nup188 isoform X1 K14311 NUP188; nuclear pore complex protein Nup188
E 126770257 nuclear pore complex protein Nup154 K14312 NUP155; nuclear pore complex protein Nup155
E 126774159 nuclear pore complex protein Nup160 homolog K14303 NUP160; nuclear pore complex protein Nup160
E 126768696 nucleoporin Nup35 K14313 NUP35; nuclear pore complex protein Nup53
E 126777969 nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 126776809 nuclear pore complex protein Nup58 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 126772625 nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 126775172 nucleoporin SEH1 K14299 SEH1; nucleoporin SEH1
E 126771618 aladin-like K14320 AAAS; aladin
E 126776140 mRNA export factor Gle1 K18723 GLE1; nucleoporin GLE1
E 126769465 nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 126776345 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 126775877 NTF2-related export protein K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 126769876 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 126769005 acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 126769497 ELAV-like protein 1 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 126777560 ELAV-like protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 126771158 ELAV-like protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 126771325 ELAV-like protein 1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 126771535 FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 126774788 transitional endoplasmic reticulum ATPase TER94 K13525 VCP; transitional endoplasmic reticulum ATPase
E 126772909 protein N-lysine methyltransferase METTL21D-like K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 126771103 exportin-1 K14290 XPO1; exportin-1
E 126779449 exportin-7 K18460 XPO7; exportin-7
D eIF4F and regulatory proteins
E 126768718 eukaryotic translation initiation factor 4E1-like K03259 EIF4E; translation initiation factor 4E
E 126768726 eukaryotic translation initiation factor 4E1-like K03259 EIF4E; translation initiation factor 4E
E 126772727 eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 126780914 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E 126781660 eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 126772683 eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 126775294 eukaryotic translation initiation factor 4H-like isoform X1 K24086 EIF4H; translation initiation factor 4H
E 126771698 eukaryotic translation initiation factor 4E-binding protein K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 126780341 protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 126773052 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 126779882 cytoplasmic FMR1-interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 126779997 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 126772689 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 126778542 putative ATP-dependent RNA helicase Pl10 isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 126768987 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 126775934 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 126780552 deformed epidermal autoregulatory factor 1 isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 126776910 malignant T-cell-amplified sequence 1 homolog K07575 MCTS; malignant T-cell-amplified sequence
E 126773901 density-regulated protein homolog K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E 126774064 partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 126772709 heterogeneous nuclear ribonucleoprotein 87F-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 126772710 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 126779596 RNA-binding protein Musashi homolog Rbp6-like isoform X1 K14411 MSI; RNA-binding protein Musashi
E 126770030 RNA-binding protein Musashi homolog Rbp6 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 126773369 heterogeneous nuclear ribonucleoprotein 27C isoform X1 K14411 MSI; RNA-binding protein Musashi
E 126773876 protein HBS1 K14416 HBS1; elongation factor 1 alpha-like protein
E 126769870 protein pelota isoform X1 K06965 PELO; protein pelota
E 126775068 polyadenylate-binding protein 2-B-like K14396 PABPN1; polyadenylate-binding protein 2
E 126768194 DEAD-box helicase Dbp80 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 126781185 pre-mRNA-splicing factor syf1 homolog K12867 SYF1; pre-mRNA-splicing factor SYF1
E 126776398 SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 126778476 regulator of chromosome condensation-like K11493 RCC1; regulator of chromosome condensation
E 126777670 la-related protein 6 K18733 LARP6; la-related protein 6
E 126777940 transcriptional activator protein Pur-alpha isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
E 126774110 leukocyte receptor cluster member 8 homolog K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E 126779550 eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 126770527 eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 126773124 regulator of nonsense transcripts 1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 126781271 regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
D Protein phosphatase 2A
E 126771646 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 126778134 serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 126778168 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 126773644 uncharacterized protein LOC126773644 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 126777211 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 126775962 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 126775855 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 126774281 serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 126773320 nonsense-mediated mRNA decay factor SMG5 K11125 SMG5; protein SMG5
E 126769346 nonsense-mediated mRNA decay factor SMG9-like K18735 SMG9; protein SMG9
E 126773195 probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 126770120 GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 126770916 protein penguin K14844 PUF6; pumilio homology domain family member 6
E 126779049 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 126774957 protein bicaudal D isoform X1 K18739 BICD; protein bicaudal D
E 126775519 egalitarian protein homolog K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E 126781598 piRNA biogenesis protein EXD1-like K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 126770812 actin-5C K05692 ACTB_G1; actin beta/gamma 1
E 126770813 actin, cytoplasmic A3a K05692 ACTB_G1; actin beta/gamma 1
E 126774479 myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 126770208 T-box transcription factor TBX6-like K10180 TBX6; T-box protein 6
E 126771965 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
E 126773600 protein deadpan-like K09090 HESN; hairy and enhancer of split, invertebrate
E 126771970 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
E 126773978 protein hairy K09090 HESN; hairy and enhancer of split, invertebrate
D Trans-acting binding proteins
E 126777349 far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 126772537 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
E 126773172 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 126769591 elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 126781097 arf-GAP domain and FG repeat-containing protein 1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 126768786 polypyrimidine tract-binding protein 2 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 126772762 RNA-binding protein squid isoform X1 K03102 SQD; squid
E 126779997 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 126772689 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 126773052 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 126779882 cytoplasmic FMR1-interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 126768952 poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 126771287 CUGBP Elav-like family member 1 isoform X1 K02177 BRU; bruno
E 126777543 maternal protein exuperantia K18745 EXU; maternal protein exuperantia
E 126780794 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
E 126775458 sex-lethal homolog isoform X1 K18747 SXL; protein sex-lethal
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 126768416 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 126771892 protein argonaute-2 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 126771082 protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 126768718 eukaryotic translation initiation factor 4E1-like K03259 EIF4E; translation initiation factor 4E
E 126768726 eukaryotic translation initiation factor 4E1-like K03259 EIF4E; translation initiation factor 4E
E 126772727 eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 126773124 regulator of nonsense transcripts 1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 126778542 putative ATP-dependent RNA helicase Pl10 isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 126771057 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 126773391 RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 126780794 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
E 126781175 LIM domain-containing protein jub K16682 AJUBA; LIM domain-containing protein
E 126775941 RNA helicase Mov10l1-like isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 126768206 transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 126774281 serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 126773320 nonsense-mediated mRNA decay factor SMG5 K11125 SMG5; protein SMG5
E 126769702 protein TIS11 isoform X1 K15308 TTP; tristetraprolin
E 126768451 protein lin-28 homolog K18754 LIN28; protein lin-28
E 126771584 protein bicaudal C isoform X1 K18756 BICC1; protein bicaudal C
E 126772709 heterogeneous nuclear ribonucleoprotein 87F-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 126772710 heterogeneous nuclear ribonucleoprotein A1-like isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 126768172 cAMP-dependent protein kinase catalytic subunit 1-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 126768174 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 126780523 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 126772374 cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 126779883 la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
D P-body specific factors
E 126773269 m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 126773825 mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 126772435 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 126778944 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 126771988 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 126780146 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 126770684 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 126777715 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 126771980 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 126772884 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 126769472 kinesin light chain isoform X1 K10407 KLC; kinesin light chain
E 126779049 unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 126777983 tubulin alpha chain K07374 TUBA; tubulin alpha
E 126780731 tubulin alpha-1 chain-like K07374 TUBA; tubulin alpha
E 126768514 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 126769145 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 126772359 tubulin alpha chain-like isoform X1 K07374 TUBA; tubulin alpha
E 126779997 cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 126772689 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 126770754 protein Gawky isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 126780443 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 126776251 regulator of gene activity isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 126773721 CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 126777845 uncharacterized protein LOC126777845 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 126772810 CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 126768209 CCR4-NOT transcription complex subunit 7-like isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 126768210 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 126774541 DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 126773777 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 126780360 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 126770075 protein Tob1 K14443 TOB; protein Tob/BTG
E 126775150 enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 126780985 enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 126781271 regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 126774956 protein wech isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 126773769 RING finger protein nhl-1 isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 126775785 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 126773660 YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 126776105 nucleolysin TIAR K13201 TIA1; nucleolysin TIA-1/TIAR
E 126780037 cytotoxic granule associated RNA binding protein TIA1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 126768987 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 126773052 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 126772653 ras GTPase-activating protein-binding protein 2 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 126777833 eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 126770868 eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 126780914 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E 126776213 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 126772683 eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 126781660 eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 126772485 ribosomal protein S6 kinase 2 beta K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 126771641 guanine nucleotide-binding protein subunit beta-like protein K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 126769465 nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 126776345 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 126769896 histone deacetylase 6 isoform X1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 126781664 tudor domain-containing protein 3 K18404 TDRD3; tudor domain-containing protein 3
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 126773825 mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 126773269 m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 126771057 ATP-dependent RNA helicase me31b K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 126775150 enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 126780985 enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
D Lsm complex
E 126772435 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 126778944 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 126771988 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 126780146 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 126770684 U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 126777715 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 126771980 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 126772884 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 126768416 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 126775888 5'-3' exoribonuclease 2 homolog isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 126778532 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E 126778287 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 126779616 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 126773916 exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 126777582 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 126775899 exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 126768475 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 126768263 exosome complex component RRP43-like K12586 RRP43; exosome complex component RRP43
E 126781707 exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 126769551 nuclear nucleic acid-binding protein C1D-like K12592 C1D; exosome complex protein LRP1
E 126780900 M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 126777059 non-canonical poly(A) RNA polymerase protein Trf4-1-like K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 126776112 exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 126775934 helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 126770282 tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 126773397 WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
E 126773400 WD repeat-containing protein 61-like K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 126772810 CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 126780443 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 126776251 regulator of gene activity isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 126773721 CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 126777845 uncharacterized protein LOC126777845 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 126768209 CCR4-NOT transcription complex subunit 7-like isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 126768210 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 126776390 CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 126775532 CCR4-NOT transcription complex subunit 10-A K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 126773777 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 126780360 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 126769839 pre-piRNA 3'-exonuclease trimmer-like isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 126771910 ATP-dependent DNA/RNA helicase DHX36-like K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 126770075 protein Tob1 K14443 TOB; protein Tob/BTG
E 126778532 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 126780348 2',5'-phosphodiesterase 12 isoform X1 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 126769469 protein Smaug isoform X1 K27396 SMG; protein Smaug
E 126775048 focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 126771929 probable ribonuclease ZC3H12B isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 126769660 ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 126772412 probable oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 126780632 alpha-enolase-like K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 126773756 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 126776203 polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 126768453 ATP-dependent 6-phosphofructokinase isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 126779477 heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
E 126771601 heat shock protein 60A-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E 126775795 63 kDa chaperonin, mitochondrial-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 126779616 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 126778287 exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 126777582 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 126768475 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024