+D GENES KO
#
KEGG Orthology (KO) - Candidatus Nitrosopumilus sp. SW
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:niw00010]
D Nisw_04150 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D Nisw_08320 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D Nisw_02100 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Nisw_08805 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Nisw_00595 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Nisw_02395 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Nisw_04090 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Nisw_02190 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Nisw_08800 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Nisw_02750 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Nisw_02745 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_02860 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:niw00020]
D Nisw_07970 citrate (Si)-synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D Nisw_06550 aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D Nisw_07070 isocitrate/isopropylmalate dehydrogenase family protein K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
D Nisw_02750 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Nisw_02745 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Nisw_07840 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Nisw_07845 succinyl-CoA synthetase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Nisw_03650 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Nisw_03635 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Nisw_03645 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Nisw_03640 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_02860 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00030 Pentose phosphate pathway [PATH:niw00030]
D Nisw_04150 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D Nisw_03415 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Nisw_03420 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Nisw_03410 fsa; fructose-6-phosphate aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D Nisw_03860 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_05140 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Nisw_07905 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Nisw_08320 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D Nisw_02100 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
C 00040 Pentose and glucuronate interconversions
D Nisw_08065 L-iditol 2-dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14]
C 00051 Fructose and mannose metabolism [PATH:niw00051]
D Nisw_06020 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Nisw_04150 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_02170 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_02695 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_04205 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D Nisw_08065 L-iditol 2-dehydrogenase K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14]
D Nisw_08320 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D Nisw_02100 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Nisw_08805 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:niw00052]
D Nisw_02185 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism [PATH:niw00500]
D Nisw_04190 rfbF; glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_04150 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D Nisw_06020 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00620 Pyruvate metabolism [PATH:niw00620]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_02750 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Nisw_02745 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_04415 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Nisw_00485 methylmalonyl-CoA epimerase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D Nisw_08210 VOC family protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D Nisw_03290 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_02860 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D Nisw_08800 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_08090 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:niw00630]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_07970 citrate (Si)-synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D Nisw_06550 aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_08785 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Nisw_08760 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Nisw_08780 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Nisw_02755 D-glycerate dehydrogenase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26]
D Nisw_01470 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D Nisw_04110 pyridoxal phosphate-dependent aminotransferase K28204 K28204; glyoxylate aminotransferase [EC:2.6.1.-]
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Nisw_07905 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Nisw_03835 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
C 00640 Propanoate metabolism [PATH:niw00640]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_08785 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Nisw_08760 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Nisw_08780 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Nisw_07845 succinyl-CoA synthetase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Nisw_07840 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Nisw_07970 citrate (Si)-synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D Nisw_06550 aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
C 00650 Butanoate metabolism [PATH:niw00650]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_08490 phaC; class III poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
D Nisw_08495 hypothetical protein K22881 phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE
D Nisw_03650 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Nisw_03635 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Nisw_03645 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Nisw_03640 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Nisw_03935 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D Nisw_02750 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Nisw_02745 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Nisw_00625 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Nisw_06665 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08080 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08085 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:niw00660]
D Nisw_06665 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08080 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08085 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Nisw_07845 succinyl-CoA synthetase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Nisw_07840 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Nisw_02705 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02715 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02700 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02710 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_08095 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:niw00562]
D Nisw_03590 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Nisw_01655 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D Nisw_08805 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:niw00190]
D Nisw_03550 NADH-quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D Nisw_03545 NADH-quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D Nisw_03540 NADH-quinone oxidoreductase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D Nisw_03535 NADH-quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D Nisw_03530 nuoH; NADH-quinone oxidoreductase subunit NuoH K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D Nisw_03525 NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D Nisw_03515 nuoK; NADH-quinone oxidoreductase subunit NuoK K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D Nisw_03505 NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D Nisw_03510 NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D Nisw_03500 NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D Nisw_03520 NADH-quinone oxidoreductase subunit J K05578 ndhG; NAD(P)H-quinone oxidoreductase subunit 6 [EC:7.1.1.2]
D Nisw_04970 NAD(P)/FAD-dependent oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D Nisw_03650 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Nisw_03635 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Nisw_03645 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Nisw_03640 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Nisw_06195 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D Nisw_05960 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_07620 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_04075 cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D Nisw_04080 hypothetical protein K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D Nisw_05595 V-type ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D Nisw_05600 V-type ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D Nisw_05540 ATPase K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D Nisw_05605 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D Nisw_05590 V-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D Nisw_08060 ATPase K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D Nisw_05885 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D Nisw_05585 ATPase K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D Nisw_05610 ATPase K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D Nisw_07790 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:niw00710]
D Nisw_02395 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Nisw_00595 type II glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Nisw_03415 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Nisw_03420 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Nisw_03860 rpiA; ribose-5-phosphate isomerase RpiA K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Nisw_08805 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Nisw_03410 fsa; fructose-6-phosphate aldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D Nisw_02860 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D Nisw_08800 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:niw00720]
D Nisw_08800 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03650 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Nisw_03635 succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Nisw_03645 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Nisw_03640 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Nisw_07840 succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Nisw_07845 succinyl-CoA synthetase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Nisw_03940 CoA-binding protein K18593 E6.2.1.56; 4-hydroxybutyrate---CoA ligase (ADP-forming) [EC:6.2.1.56]
D Nisw_03935 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D Nisw_08360 3-hydroxyacyl-CoA dehydrogenase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_02750 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Nisw_02745 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Nisw_06550 aconitate hydratase K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D Nisw_03565 acetyl-CoA carboxylase biotin carboxylase subunit K18603 K18603; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
D Nisw_03570 acyl-CoA carboxylase subunit beta K18604 K18604; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D Nisw_03560 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit K18605 K18605; biotin carboxyl carrier protein
D Nisw_07910 iron-containing alcohol dehydrogenase K18602 K18602; malonic semialdehyde reductase [EC:1.1.1.-]
D Nisw_07190 acyl-CoA synthetase K18594 K18594; 3-hydroxypropionyl-CoA synthetase (ADP-forming) [EC:6.2.1.-]
D Nisw_07195 enoyl-CoA hydratase/isomerase family protein K15019 K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116]
D Nisw_08785 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Nisw_08780 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Nisw_08760 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Nisw_07875 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:niw00680]
D Nisw_06415 ammonia monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D Nisw_06400 ammonia monooxygenase K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D Nisw_06405 ammonia monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Nisw_07905 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_08320 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D Nisw_02100 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Nisw_00540 LLM class flavin-dependent oxidoreductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D Nisw_05290 tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_04090 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Nisw_02190 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Nisw_07445 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Nisw_01590 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Nisw_01900 cofH; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D Nisw_01895 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D Nisw_01785 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D Nisw_01780 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D Nisw_01585 cofE; coenzyme F420-0:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
C 00910 Nitrogen metabolism [PATH:niw00910]
D Nisw_04070 hypothetical protein K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D Nisw_07440 copper oxidase K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D Nisw_06415 ammonia monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D Nisw_06400 ammonia monooxygenase K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D Nisw_06405 ammonia monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D Nisw_07175 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism [PATH:niw00920]
D Nisw_07305 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Nisw_07315 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D Nisw_07310 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Nisw_04740 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D Nisw_04880 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]
D Nisw_04875 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D Nisw_04745 phosphoadenylyl-sulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D Nisw_01505 nitrite/sulfite reductase K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]
D Nisw_05080 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D Nisw_01500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_02610 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_05560 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_06330 pyridoxal-phosphate dependent enzyme K01738 cysK; cysteine synthase [EC:2.5.1.47]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:niw00061]
D Nisw_04135 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:niw00071]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
D Nisw_07905 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
C 00564 Glycerophospholipid metabolism [PATH:niw00564]
D Nisw_05385 iron-containing alcohol dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D Nisw_05030 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D Nisw_01750 NAD(P)/FAD-dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:niw00230]
D Nisw_05455 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_05140 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Nisw_00870 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Nisw_07865 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D Nisw_07890 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Nisw_00875 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D Nisw_00885 purS; phosphoribosylformylglycinamidine synthase, purS protein K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D Nisw_00880 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Nisw_01950 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D Nisw_00520 5-(carboxyamino)imidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D Nisw_00515 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D Nisw_00855 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D Nisw_06715 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Nisw_00370 formate--phosphoribosylaminoimidazolecarboxamide ligase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D Nisw_00920 formate--phosphoribosylaminoimidazolecarboxamide ligase family protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D Nisw_06965 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Nisw_06055 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Nisw_03805 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Nisw_06265 rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D Nisw_06885 NUDIX domain-containing protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
D Nisw_04610 glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Nisw_06035 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Nisw_05745 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Nisw_05740 ArsR family transcriptional regulator K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Nisw_00500 adenylate/guanylate cyclase domain-containing protein K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
D Nisw_06870 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Nisw_06010 adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2]
D Nisw_02805 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Nisw_06240 shikimate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Nisw_07075 metallophosphoesterase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]
D Nisw_04880 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]
D Nisw_04740 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
C 00240 Pyrimidine metabolism [PATH:niw00240]
D Nisw_08035 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Nisw_08030 carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Nisw_05620 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Nisw_05615 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Nisw_07015 dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D Nisw_07020 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D Nisw_03475 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D Nisw_06880 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D Nisw_05515 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D Nisw_03805 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Nisw_06885 NUDIX domain-containing protein K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
D Nisw_00100 pyrG; CTP synthase (glutamine hydrolyzing) K01937 pyrG; CTP synthase [EC:6.3.4.2]
D Nisw_02795 AAA family ATPase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D Nisw_05740 ArsR family transcriptional regulator K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Nisw_05745 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Nisw_08820 dCMP deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Nisw_05505 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D Nisw_03885 dihydroorotase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:niw00250]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06625 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Nisw_08970 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Nisw_01650 carbon-nitrogen hydrolase family protein K13566 NIT2; omega-amidase [EC:3.5.1.3]
D Nisw_07435 aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1]
D Nisw_07300 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Nisw_03625 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Nisw_06870 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Nisw_06715 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Nisw_05620 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Nisw_05615 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Nisw_07175 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_08035 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Nisw_08030 carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Nisw_00880 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Nisw_03280 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Nisw_00870 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Nisw_04110 pyridoxal phosphate-dependent aminotransferase K28204 K28204; glyoxylate aminotransferase [EC:2.6.1.-]
C 00260 Glycine, serine and threonine metabolism [PATH:niw00260]
D Nisw_04020 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05250 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05970 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Nisw_01330 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Nisw_04785 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D Nisw_00585 pyridoxal-phosphate dependent enzyme K01733 thrC; threonine synthase [EC:4.2.3.1]
D Nisw_06165 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Nisw_07905 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Nisw_04090 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D Nisw_02190 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Nisw_07445 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Nisw_01590 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Nisw_00685 pyridoxal phosphate-dependent aminotransferase family protein K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]
D Nisw_00510 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Nisw_00120 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Nisw_00125 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:niw00270]
D Nisw_06330 pyridoxal-phosphate dependent enzyme K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Nisw_07395 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_07400 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_04520 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Nisw_06960 S-methyl-5'-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D Nisw_04145 mtnA; S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D Nisw_08715 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Nisw_04020 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05250 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05970 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Nisw_01330 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Nisw_04785 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D Nisw_03695 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_04030 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_01500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_02610 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_05560 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_01520 lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_03215 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Nisw_01570 cysteine synthase family protein K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144]
D Nisw_07445 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:niw00280]
D Nisw_03695 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_04030 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_08785 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Nisw_08760 cobalamin B12-binding domain-containing protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Nisw_08780 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Nisw_01730 NAD(P)-dependent oxidoreductase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_00625 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:niw00290]
D Nisw_00510 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Nisw_02705 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02715 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02700 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_02710 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Nisw_08095 isocitrate/isopropylmalate dehydrogenase family protein K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D Nisw_06665 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08080 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08085 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Nisw_08755 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Nisw_00300 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Nisw_03695 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_04030 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_08090 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D Nisw_04110 pyridoxal phosphate-dependent aminotransferase K28204 K28204; glyoxylate aminotransferase [EC:2.6.1.-]
C 00300 Lysine biosynthesis [PATH:niw00300]
D Nisw_01330 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Nisw_04020 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05250 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05970 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Nisw_07260 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Nisw_07295 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Nisw_07255 lysX; lysine biosynthesis protein LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
D Nisw_07290 lysX; lysine biosynthesis protein LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
D Nisw_07280 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D Nisw_07285 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D Nisw_07275 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Nisw_07250 M20/M25/M40 family metallo-hydrolase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00310 Lysine degradation [PATH:niw00310]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_02770 FAD-dependent oxidoreductase K15736 lhgO; (S)-2-hydroxyglutarate dehydrogenase [EC:1.1.5.13]
C 00220 Arginine biosynthesis [PATH:niw00220]
D Nisw_02835 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D Nisw_07300 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Nisw_03625 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Nisw_00880 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_08035 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Nisw_08030 carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Nisw_07175 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_07260 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Nisw_07295 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Nisw_07280 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D Nisw_07285 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D Nisw_07275 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Nisw_07250 M20/M25/M40 family metallo-hydrolase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
D Nisw_04110 pyridoxal phosphate-dependent aminotransferase K28204 K28204; glyoxylate aminotransferase [EC:2.6.1.-]
C 00330 Arginine and proline metabolism [PATH:niw00330]
D Nisw_03840 creatininase family protein K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D Nisw_07760 pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D Nisw_00070 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D Nisw_00430 TIGR00300 family protein K28013 E4.3.1.12; ornithine cyclodeaminase [EC:4.3.1.12]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:niw00340]
D Nisw_06115 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D Nisw_06155 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D Nisw_06145 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D Nisw_06140 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D Nisw_06150 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D Nisw_06135 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Nisw_06120 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D Nisw_01635 egtD; L-histidine N(alpha)-methyltransferase K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44]
C 00350 Tyrosine metabolism [PATH:niw00350]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00360 Phenylalanine metabolism [PATH:niw00360]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Nisw_03375 non-heme iron oxygenase ferredoxin subunit K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
D Nisw_08475 alpha/beta hydrolase K05714 mhpC; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase [EC:3.7.1.14]
C 00380 Tryptophan metabolism
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:niw00400]
D Nisw_02100 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Nisw_02105 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D Nisw_02110 aroD; type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D Nisw_02120 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D Nisw_02125 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D Nisw_02130 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D Nisw_00145 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Nisw_00140 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Nisw_00135 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D Nisw_00130 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D Nisw_00120 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Nisw_00125 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Nisw_02140 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:niw00410]
D Nisw_05440 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D Nisw_03885 dihydroorotase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
C 00430 Taurine and hypotaurine metabolism [PATH:niw00430]
D Nisw_07355 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Nisw_07175 Glu/Leu/Phe/Val dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:niw00450]
D Nisw_07395 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_07400 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_02410 cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Nisw_05210 aminotransferase class V-fold PLP-dependent enzyme K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Nisw_01555 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Nisw_04740 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D Nisw_08720 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:niw00460]
D Nisw_07355 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:niw00470]
D Nisw_07340 M20/M25/M40 family metallo-hydrolase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Nisw_00880 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Nisw_04690 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
C 00480 Glutathione metabolism [PATH:niw00480]
D Nisw_07355 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Nisw_03435 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B
B 09107 Glycan biosynthesis and metabolism
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:niw00520]
D Nisw_02425 peptidase K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D Nisw_02175 GNAT family N-acetyltransferase K00621 GNPNAT1; glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4]
D Nisw_03280 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Nisw_06020 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Nisw_04150 SIS domain-containing protein K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_02185 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D Nisw_02170 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_02695 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_04190 rfbF; glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D Nisw_04280 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
C 00541 Biosynthesis of various nucleotide sugars [PATH:niw00541]
D Nisw_04230 N-acetylneuraminate synthase K18430 legI; N,N'-diacetyllegionaminate synthase [EC:2.5.1.101]
D Nisw_04190 rfbF; glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D Nisw_04185 rfbG; CDP-glucose 4,6-dehydratase K01709 rfbG; CDP-glucose 4,6-dehydratase [EC:4.2.1.45]
D Nisw_04280 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Nisw_04275 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Nisw_04175 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Nisw_04165 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_04265 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_02170 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_02695 nucleotidyltransferase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Nisw_04205 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D Nisw_04270 WxcM-like domain-containing protein
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:niw00730]
D Nisw_02150 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D Nisw_02165 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D Nisw_03200 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Nisw_01510 thiazole biosynthesis protein K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D Nisw_06750 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D Nisw_02805 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:niw00740]
D Nisw_05820 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D Nisw_05830 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D Nisw_05810 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D Nisw_05815 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D Nisw_05805 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D Nisw_07230 DUF120 domain-containing protein K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D Nisw_07240 FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2]
D Nisw_01265 nitroreductase K19286 nfrA2; FMN reductase [NAD(P)H] [EC:1.5.1.39]
D Nisw_05345 bluB; 5,6-dimethylbenzimidazole synthase K04719 bluB; 5,6-dimethylbenzimidazole synthase [EC:1.13.11.79]
D Nisw_05455 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Nisw_00915 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:niw00750]
D Nisw_00585 pyridoxal-phosphate dependent enzyme K01733 thrC; threonine synthase [EC:4.2.3.1]
D Nisw_06165 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Nisw_06565 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D Nisw_06570 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:niw00760]
D Nisw_07520 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21]
D Nisw_07525 nadA; quinolinate synthase NadA K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D Nisw_07535 nadC; carboxylating nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D Nisw_05370 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D Nisw_08735 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D Nisw_08705 NAD+ synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D Nisw_05125 NAD-dependent deacylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D Nisw_00090 sugar kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D Nisw_02615 NAD(+)/NADH kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:niw00770]
D Nisw_06665 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08080 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Nisw_08085 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Nisw_08755 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Nisw_00300 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Nisw_05435 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D Nisw_05445 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D Nisw_05440 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D Nisw_05430 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D Nisw_06485 pantetheine-phosphate adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D Nisw_07555 DUF359 domain-containing protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D Nisw_03695 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_04030 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_03885 dihydroorotase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
C 00780 Biotin metabolism [PATH:niw00780]
D Nisw_04135 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Nisw_00675 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D Nisw_00665 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D Nisw_00680 bioB; biotin synthase BioB K01012 bioB; biotin synthase [EC:2.8.1.6]
D Nisw_08525 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism
C 00790 Folate biosynthesis [PATH:niw00790]
D Nisw_04800 folE; GTP cyclohydrolase I FolE K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D Nisw_06050 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D Nisw_06605 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Nisw_06620 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D Nisw_04805 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Nisw_04790 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Nisw_06045 DUF115 domain-containing protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
C 00670 One carbon pool by folate [PATH:niw00670]
D Nisw_07875 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Nisw_07890 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Nisw_07395 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_07400 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_03835 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D Nisw_07870 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D Nisw_04520 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Nisw_08715 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:niw00860]
D Nisw_03360 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Nisw_02340 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D Nisw_03605 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D Nisw_02445 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_04235 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_08415 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_02345 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Nisw_02440 hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D Nisw_02430 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D Nisw_02435 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D Nisw_02335 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D Nisw_02330 Lrp/AsnC family transcriptional regulator K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D Nisw_05960 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_07620 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_04540 sirohydrochlorin cobaltochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D Nisw_04700 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D Nisw_05260 cobJ; precorrin-3B C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D Nisw_04695 cobM; precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D Nisw_04535 precorrin-3B C(17)-methyltransferase K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D Nisw_04530 cobalt-precorrin-5B (C(1))-methyltransferase K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D Nisw_04705 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D Nisw_04550 cobyrinate a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D Nisw_00455 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Nisw_04555 cobO; cob(I)yrinic acid a,c-diamide adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Nisw_05980 cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D Nisw_05985 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D Nisw_05995 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D Nisw_05990 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D Nisw_05975 threonine-phosphate decarboxylase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:niw00130]
D Nisw_02090 menaquinone biosynthesis decarboxylase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D Nisw_00915 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D Nisw_07160 methyltransferase domain-containing protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D Nisw_08950 prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D Nisw_01105 radical SAM protein K18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]
D Nisw_02095 mqnC; dehypoxanthine futalosine cyclase K11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]
D Nisw_01080 ABC transporter substrate-binding protein K11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:niw00900]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_00625 hydroxymethylglutaryl-CoA synthase family protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Nisw_06105 hydroxymethylglutaryl-CoA reductase, degradative K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]
D Nisw_03340 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D Nisw_03345 gamma-glutamyl kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D Nisw_04725 DUF521 domain-containing protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D Nisw_04720 DUF126 domain-containing protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D Nisw_05905 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D Nisw_00915 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D Nisw_03350 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D Nisw_03355 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Nisw_03495 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D Nisw_06890 uppS; di-trans,poly-cis-decaprenylcistransferase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:niw00906]
D Nisw_08580 FAD-dependent oxidoreductase K02293 PDS; 15-cis-phytoene desaturase [EC:1.3.5.5]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D Nisw_03415 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D Nisw_03420 ribulose-phosphate 3-epimerase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:niw00523]
D Nisw_04280 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Nisw_04275 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Nisw_04175 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Nisw_04165 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_04265 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_04220 Gfo/Idh/MocA family oxidoreductase K13327 spnN; dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase [EC:1.1.1.384]
D Nisw_04270 WxcM-like domain-containing protein
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D Nisw_04275 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:niw00261]
D Nisw_04740 sat; sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D Nisw_04020 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05250 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Nisw_05970 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:niw00521]
D Nisw_03825 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Nisw_01655 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D Nisw_03590 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Nisw_04280 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Nisw_04275 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D Nisw_04175 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D Nisw_04165 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_04265 SDR family oxidoreductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D Nisw_04270 WxcM-like domain-containing protein
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis [PATH:niw00525]
D Nisw_04280 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Nisw_04275 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:niw00401]
D Nisw_02140 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D Nisw_00145 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Nisw_00140 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D Nisw_04135 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites
D Nisw_04520 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
D Nisw_03355 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:niw00362]
D Nisw_05715 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:niw00627]
D Nisw_04415 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Nisw_00915 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation [PATH:niw00364]
D Nisw_06795 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00625 Chloroalkane and chloroalkene degradation [PATH:niw00625]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:niw00361]
D Nisw_06795 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00623 Toluene degradation [PATH:niw00623]
D Nisw_06795 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00622 Xylene degradation
D Nisw_05715 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
D Nisw_05715 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]
C 00626 Naphthalene degradation [PATH:niw00626]
D Nisw_02270 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Nisw_07690 zinc-binding alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:niw03020]
D Nisw_03170 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D Nisw_03165 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Nisw_02675 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Nisw_07545 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Nisw_03175 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Nisw_03325 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Nisw_08335 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D Nisw_00015 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
C 03022 Basal transcription factors [PATH:niw03022]
D Nisw_01410 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01450 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01790 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_02300 transcription factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_02915 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_04895 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_04940 transcription initiation factor TFIIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_06695 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_08510 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_08560 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01865 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_06320 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_05855 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:niw03010]
D Nisw_08425 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Nisw_06355 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Nisw_00780 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D Nisw_04590 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D Nisw_02285 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D Nisw_06825 hypothetical protein K02962 RP-S17e; small subunit ribosomal protein S17e
D Nisw_05770 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D Nisw_00025 MarR family transcriptional regulator K02975 RP-S25e; small subunit ribosomal protein S25e
D Nisw_00080 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D Nisw_06000 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D Nisw_02205 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Nisw_03815 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D Nisw_07030 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
D Nisw_03335 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D Nisw_00750 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D Nisw_03275 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D Nisw_02825 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D Nisw_03130 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D Nisw_00795 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Nisw_02690 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Nisw_08330 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D Nisw_06740 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D Nisw_03135 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D Nisw_03270 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D Nisw_00790 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Nisw_06375 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D Nisw_00765 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D Nisw_00740 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D Nisw_00730 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D Nisw_03820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Nisw_02565 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D Nisw_07465 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D Nisw_02680 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D Nisw_02870 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D Nisw_07045 50S ribosomal protein L21 K02889 RP-L21e; large subunit ribosomal protein L21e
D Nisw_03810 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D Nisw_03145 50S ribosomal protein L7ae K02908 RP-L30e; large subunit ribosomal protein L30e
D Nisw_02865 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D Nisw_03850 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D Nisw_02645 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Nisw_07415 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D Nisw_07835 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Nisw_06005 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D Nisw_02950 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Nisw_04420 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Nisw_00725 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Nisw_00785 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Nisw_00800 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D Nisw_02955 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Nisw_02895 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Nisw_02980 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D Nisw_02685 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Nisw_00770 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D Nisw_02815 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Nisw_02830 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D Nisw_00745 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D Nisw_00735 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D Nisw_00775 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D Nisw_00755 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Nisw_02820 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
C 00970 Aminoacyl-tRNA biosynthesis [PATH:niw00970]
D Nisw_03680 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_03910 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_06475 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_02045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_04115 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_06210 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_00810 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Nisw_03615 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Nisw_04480 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Nisw_02550 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Nisw_02575 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_04600 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_05760 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_03395 tRNA-His K14226 tRNA-His; tRNA His
D Nisw_06465 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Nisw_02365 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03830 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_04445 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03620 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Nisw_04050 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Nisw_03480 tRNA-Met K14230 tRNA-Met; tRNA Met
D Nisw_06095 tRNA-Met K14230 tRNA-Met; tRNA Met
D Nisw_00460 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Nisw_01845 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Nisw_05090 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Nisw_01285 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_03745 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_07080 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_06445 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_06760 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_07750 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_06555 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Nisw_04010 tRNA-Val K14237 tRNA-Val; tRNA Val
D Nisw_05350 tRNA-Val K14237 tRNA-Val; tRNA Val
D Nisw_03360 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Nisw_00395 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Nisw_00400 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Nisw_00390 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Nisw_04435 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D Nisw_04440 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D Nisw_03015 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Nisw_00385 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_08115 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_04635 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Nisw_00065 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Nisw_06360 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Nisw_08700 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Nisw_08720 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Nisw_04310 hypothetical protein K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D Nisw_06575 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Nisw_03020 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Nisw_07860 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Nisw_01970 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Nisw_01465 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Nisw_01600 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Nisw_03765 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Nisw_06510 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Nisw_06515 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Nisw_05265 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Nisw_06505 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
C 03015 mRNA surveillance pathway [PATH:niw03015]
D Nisw_00320 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1
D Nisw_04385 mRNA surveillance protein pelota K06965 PELO; protein pelota
C 03008 Ribosome biogenesis in eukaryotes [PATH:niw03008]
D Nisw_07010 ribonucleotide-diphosphate reductase subunit beta K14564 NOP56; nucleolar protein 56
D Nisw_04565 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Nisw_05755 ribosome biogenesis protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D Nisw_00760 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Nisw_03760 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D Nisw_02665 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1
D Nisw_06240 shikimate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Nisw_06915 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:niw03060]
D Nisw_02810 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D Nisw_02220 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Nisw_04405 ffs; signal recognition particle sRNA K01983 ffs; signal recognition particle 4.5S RNA
D Nisw_02840 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Nisw_02885 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Nisw_02290 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19
D Nisw_00905 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_07145 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_00900 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D Nisw_03925 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum [PATH:niw04141]
D Nisw_02885 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Nisw_04570 hypothetical protein K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D Nisw_04425 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04955 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_01625 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_04915 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_04960 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_05500 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_07580 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_04560 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
D Nisw_07835 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Nisw_02205 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 04122 Sulfur relay system [PATH:niw04122]
D Nisw_03200 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Nisw_01500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_02610 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_05560 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Nisw_01575 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Nisw_06170 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D Nisw_07610 M67 family peptidase
C 03050 Proteasome [PATH:niw03050]
D Nisw_00715 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_07165 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_01345 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Nisw_05390 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:niw03018]
D Nisw_06070 RNA-binding protein K07573 CSL4; exosome complex component CSL4
D Nisw_02660 RNA-binding protein K03679 RRP4; exosome complex component RRP4
D Nisw_02650 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D Nisw_02655 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Nisw_07740 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Nisw_04460 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:niw03030]
D Nisw_07225 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Nisw_03945 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Nisw_07000 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Nisw_08815 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Nisw_05000 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Nisw_05035 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Nisw_03730 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Nisw_04620 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Nisw_04625 DNA primase K18882 priL; DNA primase large subunit
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_03740 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D Nisw_03580 AAA family ATPase K04800 rfcL; replication factor C large subunit
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:niw03410]
D Nisw_06215 DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Nisw_04730 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Nisw_08145 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Nisw_02015 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D Nisw_03030 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Nisw_08150 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Nisw_04630 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Nisw_06370 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:niw03420]
D Nisw_07945 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D Nisw_07940 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D Nisw_07950 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D Nisw_00015 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
D Nisw_02625 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:niw03430]
D Nisw_06370 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Nisw_06440 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination [PATH:niw03440]
D Nisw_06370 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Nisw_04510 recombinase RecA K04482 RAD51; DNA repair protein RAD51
C 03450 Non-homologous end-joining
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway [PATH:niw03460]
D Nisw_04510 recombinase RecA K04482 RAD51; DNA repair protein RAD51
D Nisw_02625 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D Nisw_07540 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D Nisw_02890 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus and Alphavirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03273 Virion - Lassa virus and SFTS virus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:niw02010]
D Nisw_07305 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Nisw_07315 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D Nisw_07310 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Nisw_00355 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D Nisw_00365 phnE; phosphonate ABC transporter, permease protein PhnE K02042 phnE; phosphonate transport system permease protein
D Nisw_00360 ATP-binding cassette domain-containing protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D Nisw_05640 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D Nisw_05650 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D Nisw_05645 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Nisw_05465 ABC transporter permease K09808 lolC_E_F; lipoprotein-releasing system permease protein
D Nisw_05470 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:niw03070]
D Nisw_02810 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D Nisw_02840 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Nisw_02220 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Nisw_00905 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_07145 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_00900 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:niw02020]
D Nisw_05785 CoA ester lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D Nisw_08160 HAMP domain-containing histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
D Nisw_01925 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D Nisw_06300 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D Nisw_07150 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_02970 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_04045 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_05795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_08170 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_06195 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04082 Neuroactive ligand signaling
C 04081 Hormone signaling
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
D Nisw_02885 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C 04142 Lysosome
C 04146 Peroxisome [PATH:niw04146]
D Nisw_03340 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D Nisw_01160 superoxide dismutase K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
D Nisw_02850 superoxide dismutase K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:niw02024]
D Nisw_00145 anthranilate synthase component I family protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Nisw_00140 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Nisw_08070 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase K08321 lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [EC:2.3.1.245]
D Nisw_01825 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Nisw_01215 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Nisw_01220 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Nisw_08125 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Nisw_02810 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D Nisw_02840 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Nisw_02220 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
D Nisw_02970 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_04045 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_05795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_08170 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04981 Folate transport and metabolism [PATH:niw04981]
D Nisw_07870 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D Nisw_05040 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Nisw_07395 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_07400 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
C 04980 Cobalamin transport and metabolism [PATH:niw04980]
D Nisw_00455 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Nisw_08775 meaB; methylmalonyl Co-A mutase-associated GTPase MeaB K07588 MMAA; GTPase [EC:3.6.5.-]
D Nisw_07395 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D Nisw_07400 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
C 04382 Cornified envelope formation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance [PATH:niw01502]
D Nisw_07340 M20/M25/M40 family metallo-hydrolase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Nisw_04015 UDP-glucuronosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:niw01000]
C 01001 Protein kinases [BR:niw01001]
D Nisw_06260 Kae1-associated serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Nisw_06915 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Nisw_08160 HAMP domain-containing histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:niw01009]
D Nisw_06905 translation initiation factor IF-2 K03238 EIF2S2; translation initiation factor 2 subunit 2
D Nisw_08715 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Nisw_01590 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:niw01002]
D Nisw_00425 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Nisw_04610 glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Nisw_06035 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Nisw_04295 peptidase C26 K23150 E3.5.1.129; N5-(cytidine 5'-diphosphoramidyl)-L-glutamine hydrolase [EC:3.5.1.129]
D Nisw_00870 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Nisw_03280 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Nisw_06625 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Nisw_08970 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Nisw_08765 M1 family peptidase K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-]
D Nisw_07775 M3 family oligoendopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D Nisw_03435 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D Nisw_01850 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D Nisw_02775 hypothetical protein K01342 aprE; subtilisin [EC:3.4.21.62]
D Nisw_02855 peptidase S8 K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-]
D Nisw_03925 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Nisw_05710 rhomboid family intramembrane serine protease K07059 rho2; rhomboid family protease [EC:3.4.21.105]
D Nisw_00715 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_07165 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_01345 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Nisw_05390 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Nisw_07355 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Nisw_01905 TldD/PmbA family protein K03592 pmbA; PmbA protein
D Nisw_08155 TldD/PmbA family protein K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:niw01003]
D Nisw_03720 UDP-N-acetylglucosamine-1-phosphate transferase K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]
D Nisw_04570 hypothetical protein K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D Nisw_04655 glycosyltransferase family 2 protein K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:niw01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:niw01011]
D Nisw_07340 M20/M25/M40 family metallo-hydrolase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Nisw_04690 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D Nisw_04015 UDP-glucuronosyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01004 Lipid biosynthesis proteins [BR:niw01004]
D Nisw_04135 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Nisw_00410 AMP-dependent synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Nisw_01305 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:niw01006]
D Nisw_03355 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Nisw_03495 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D Nisw_08950 prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D Nisw_05960 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_07620 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:niw01007]
D Nisw_01970 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Nisw_03360 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Nisw_05265 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Nisw_06505 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Nisw_08700 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Nisw_01465 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Nisw_08720 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Nisw_07860 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Nisw_06575 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Nisw_03020 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Nisw_00385 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_08115 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_03765 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Nisw_04635 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Nisw_06360 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Nisw_01600 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Nisw_00065 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Nisw_03015 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Nisw_06510 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Nisw_06515 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Nisw_00415 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_02135 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Nisw_06125 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Nisw_00685 pyridoxal phosphate-dependent aminotransferase family protein K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]
D Nisw_07275 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Nisw_00675 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D Nisw_02445 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_04235 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_08415 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Nisw_03695 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Nisw_04030 branched-chain amino acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:niw03000]
D Nisw_01865 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_06320 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_02945 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D Nisw_05965 Lrp/AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D Nisw_08585 histidine kinase K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator
D Nisw_08230 transcriptional repressor K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D Nisw_02460 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D Nisw_04370 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D Nisw_08180 transcriptional regulator K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D Nisw_08525 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D Nisw_04365 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Nisw_08010 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Nisw_08880 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Nisw_05635 CopG family ribbon-helix-helix protein K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D Nisw_08215 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 03021 Transcription machinery [BR:niw03021]
D Nisw_00015 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
D Nisw_01410 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01450 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01790 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_02300 transcription factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_02915 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_04895 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_04940 transcription initiation factor TFIIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_06695 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_08510 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_08560 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Nisw_01865 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_06320 TATA box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Nisw_05855 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D Nisw_07540 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D Nisw_02890 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D Nisw_04780 GTPase K24104 GPN; GPN-loop GTPase
D Nisw_03140 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D Nisw_03165 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Nisw_03170 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D Nisw_02675 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Nisw_07545 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Nisw_03175 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Nisw_03325 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Nisw_08335 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D Nisw_05240 transcription factor S K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:niw03019]
D Nisw_07540 DNA-directed RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4
D Nisw_02890 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D Nisw_04425 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04955 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04385 mRNA surveillance protein pelota K06965 PELO; protein pelota
D Nisw_00320 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Nisw_06070 RNA-binding protein K07573 CSL4; exosome complex component CSL4
D Nisw_02660 RNA-binding protein K03679 RRP4; exosome complex component RRP4
D Nisw_02655 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41
D Nisw_02650 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42
D Nisw_07740 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Nisw_04460 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
C 03041 Spliceosome
C 03011 Ribosome [BR:niw03011]
D Nisw_06355 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Nisw_00780 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D Nisw_04590 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D Nisw_02285 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D Nisw_06825 hypothetical protein K02962 RP-S17e; small subunit ribosomal protein S17e
D Nisw_05770 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D Nisw_00025 MarR family transcriptional regulator K02975 RP-S25e; small subunit ribosomal protein S25e
D Nisw_00080 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D Nisw_06000 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D Nisw_02205 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Nisw_03815 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D Nisw_07030 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
D Nisw_00730 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D Nisw_03820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Nisw_02565 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D Nisw_07465 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D Nisw_02680 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D Nisw_02870 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D Nisw_07045 50S ribosomal protein L21 K02889 RP-L21e; large subunit ribosomal protein L21e
D Nisw_03810 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D Nisw_03145 50S ribosomal protein L7ae K02908 RP-L30e; large subunit ribosomal protein L30e
D Nisw_02865 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D Nisw_03850 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D Nisw_02645 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Nisw_07415 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D Nisw_07835 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Nisw_06005 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e
D Nisw_03335 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D Nisw_00750 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D Nisw_03275 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D Nisw_02825 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D Nisw_03130 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D Nisw_00795 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Nisw_02690 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Nisw_08330 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D Nisw_06740 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D Nisw_03135 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D Nisw_03270 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D Nisw_00790 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Nisw_06375 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D Nisw_00765 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D Nisw_00740 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D Nisw_02950 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Nisw_04420 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Nisw_00725 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Nisw_00785 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Nisw_00800 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D Nisw_02955 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Nisw_02895 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Nisw_02685 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Nisw_00770 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D Nisw_02815 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Nisw_02830 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D Nisw_00745 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D Nisw_00735 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D Nisw_00775 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D Nisw_00755 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Nisw_02820 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D Nisw_02980 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12
D Nisw_08425 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:niw03009]
D Nisw_07010 ribonucleotide-diphosphate reductase subunit beta K14564 NOP56; nucleolar protein 56
D Nisw_04565 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Nisw_05755 ribosome biogenesis protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D Nisw_06920 RNA-binding protein K06961 KRR1; ribosomal RNA assembly protein
D Nisw_06915 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Nisw_06240 shikimate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Nisw_01830 DUF367 family protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D Nisw_03445 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D Nisw_00760 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Nisw_03760 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D Nisw_02665 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1
D Nisw_04425 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04955 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_07005 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D Nisw_03820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Nisw_03140 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA
D Nisw_07060 ribose ABC transporter permease K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D Nisw_06990 RlmE family RNA methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D Nisw_07040 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D Nisw_03460 rimI; ribosomal-protein-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Nisw_07740 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Nisw_05865 hflX; GTPase HflX K03665 hflX; GTPase
D Nisw_06840 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Nisw_06245 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
D Nisw_08550 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:niw03016]
D Nisw_00760 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Nisw_05765 RNase P subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D Nisw_05130 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Nisw_06725 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Nisw_03785 archease K24956 ZBTB8OS; protein archease
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Nisw_03360 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Nisw_01600 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Nisw_07860 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Nisw_03020 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Nisw_08720 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Nisw_01465 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Nisw_03015 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Nisw_04635 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Nisw_00065 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Nisw_06360 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Nisw_08700 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Nisw_06575 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Nisw_03765 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Nisw_06510 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Nisw_06515 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Nisw_05265 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Nisw_06505 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Nisw_02880 D-tyrosyl-tRNA(Tyr) deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Nisw_00315 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Nisw_08370 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Nisw_07430 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D Nisw_06995 tRNA (guanine-N1)-methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Nisw_03450 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Nisw_01365 tRNA (adenine-N1)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Nisw_06270 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D Nisw_02790 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Nisw_07660 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D Nisw_02215 pseudouridine synthase K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D Nisw_03200 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Nisw_06260 Kae1-associated serine/threonine protein kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Nisw_06250 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D Nisw_01965 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D Nisw_06840 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Nisw_06835 RNA methyltransferase K06963 TAN1; tRNA acetyltransferase TAN1
D Nisw_04875 3'(2'),5'-bisphosphate nucleotidase CysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D Nisw_01765 rnpB; RNase P RNA component K01978 rnpB; RNase P catalytic RNA component
D Nisw_05100 cca; CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D Nisw_02560 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Nisw_08300 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Nisw_05105 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D Nisw_01970 lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Nisw_00385 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_08115 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Nisw_06290 dusB; tRNA dihydrouridine synthase DusB K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D Nisw_05135 methyltransferase domain-containing protein K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Nisw_05860 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D Nisw_01575 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Nisw_04790 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Nisw_06605 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Nisw_04805 7-carboxy-7-deazaguanine synthase QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Nisw_06235 tgtA; tRNA guanosine(15) transglycosylase TgtA K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Nisw_06090 DUF1743 domain-containing protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
C 03012 Translation factors [BR:niw03012]
D Nisw_02250 translation initiation factor 1A K03236 EIF1A; translation initiation factor 1A
D Nisw_02935 translation initiation factor 1A K03236 EIF1A; translation initiation factor 1A
D Nisw_01800 yciH; stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1
D Nisw_04560 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
D Nisw_06905 translation initiation factor IF-2 K03238 EIF2S2; translation initiation factor 2 subunit 2
D Nisw_04585 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3
D Nisw_02230 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A
D Nisw_03800 translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B
D Nisw_03760 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Nisw_07635 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta
D Nisw_01070 elongation factor EF-2 K03234 EEF2; elongation factor 2
D Nisw_06085 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D Nisw_02225 diphthine--ammonia ligase K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D Nisw_00320 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1
D Nisw_07065 methyltransferase domain-containing protein K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D Nisw_07650 peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:niw03110]
D Nisw_04460 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D Nisw_05045 thermosome subunit K22447 cct; archaeal chaperonin
D Nisw_06015 thermosome subunit K22447 cct; archaeal chaperonin
D Nisw_04455 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Nisw_04465 grpE; nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D Nisw_01625 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_04915 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_04960 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_05500 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_07580 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D Nisw_02845 pfdA; prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit
D Nisw_02630 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit
D Nisw_02775 hypothetical protein K01342 aprE; subtilisin [EC:3.4.21.62]
D Nisw_02855 peptidase S8 K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-]
D Nisw_04975 peptidylprolyl isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Nisw_05325 peptidylprolyl isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Nisw_05380 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D Nisw_08845 peptidylprolyl isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D Nisw_03795 trxA; thioredoxin K03671 TXN; thioredoxin
D Nisw_03915 trxA; thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:niw04131]
D Nisw_03805 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Nisw_04425 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04955 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04510 recombinase RecA K04482 RAD51; DNA repair protein RAD51
D Nisw_02885 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Nisw_04560 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:niw04121]
D Nisw_07835 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Nisw_02205 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Nisw_07030 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
D Nisw_04510 recombinase RecA K04482 RAD51; DNA repair protein RAD51
C 03051 Proteasome [BR:niw03051]
D Nisw_00715 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_07165 archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Nisw_01345 proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Nisw_05390 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03032 DNA replication proteins [BR:niw03032]
D Nisw_03945 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Nisw_04565 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Nisw_02625 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D Nisw_07125 DNA topoisomerase I K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
D Nisw_07225 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Nisw_05005 AAA family ATPase K10725 cdc6A; archaeal cell division control protein 6
D Nisw_03730 minichromosome maintenance protein MCM K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Nisw_04620 DNA primase K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Nisw_04625 DNA primase K18882 priL; DNA primase large subunit
D Nisw_03735 DNA replication complex GINS family protein K09723 ginS; DNA replication factor GINS
D Nisw_05060 DNA replication complex GINS family protein K09723 ginS; DNA replication factor GINS
D Nisw_07000 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Nisw_08815 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Nisw_05035 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Nisw_05000 DNA-directed DNA polymerase II small subunit K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Nisw_03580 AAA family ATPase K04800 rfcL; replication factor C large subunit
D Nisw_03740 replication factor C small subunit K04801 rfcS; replication factor C small subunit
D Nisw_06440 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Nisw_06930 DNA topoisomerase IV subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D Nisw_06925 DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
C 03036 Chromosome and associated proteins [BR:niw03036]
D Nisw_00720 hypothetical protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D Nisw_06815 histone K24450 hmf; DNA-binding protein
D Nisw_00010 DNA-binding protein K03622 albA; DNA/RNA-binding protein Alba
D Nisw_01680 DNA-binding protein K03622 albA; DNA/RNA-binding protein Alba
D Nisw_02925 DNA-binding protein K03622 albA; DNA/RNA-binding protein Alba
D Nisw_03670 DNA-binding protein K03622 albA; DNA/RNA-binding protein Alba
D Nisw_01645 chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D Nisw_02275 chromosome segregation protein ScpA K05896 scpA; segregation and condensation protein A
D Nisw_02280 SMC-Scp complex subunit ScpB K06024 scpB; segregation and condensation protein B
D Nisw_07425 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Nisw_08215 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D Nisw_07550 iron-sulfur cluster carrier protein ApbC K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:niw03400]
D Nisw_02875 MGMT family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Nisw_08650 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Nisw_08145 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D Nisw_06215 DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Nisw_04730 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Nisw_05245 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Nisw_08310 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Nisw_00015 DNA-directed RNA polymerase subunit K K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
D Nisw_02625 heavy metal resistance protein CzcA K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D Nisw_04510 recombinase RecA K04482 RAD51; DNA repair protein RAD51
D Nisw_02145 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Nisw_03030 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Nisw_08150 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Nisw_02015 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D Nisw_04630 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Nisw_01740 DUF99 family protein K09120 dU; endonuclease dU
D Nisw_06370 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Nisw_07945 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D Nisw_07940 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D Nisw_07950 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D Nisw_06440 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Nisw_07490 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
D Nisw_07495 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D Nisw_07035 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D Nisw_07500 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D Nisw_07505 DNA double-strand break repair nuclease NurA K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
D Nisw_03725 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Nisw_01690 DNA polymerase IV K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D Nisw_00280 helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Nisw_04505 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Nisw_05745 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Nisw_08605 hypothetical protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:niw03029]
D Nisw_06195 cytochrome bc complex cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D Nisw_00760 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Nisw_05265 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Nisw_03020 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Nisw_04635 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Nisw_01465 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Nisw_00395 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Nisw_00400 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Nisw_00390 hypothetical protein K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Nisw_04460 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D Nisw_04465 grpE; nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D Nisw_04455 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Nisw_03200 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Nisw_07550 iron-sulfur cluster carrier protein ApbC K03593 mrp; ATP-binding protein involved in chromosome partitioning
D Nisw_05960 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Nisw_07620 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:niw02000]
D Nisw_07305 ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Nisw_07315 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein
D Nisw_07310 ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Nisw_00355 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D Nisw_00365 phnE; phosphonate ABC transporter, permease protein PhnE K02042 phnE; phosphonate transport system permease protein
D Nisw_00360 ATP-binding cassette domain-containing protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D Nisw_01825 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Nisw_01215 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Nisw_01220 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Nisw_08125 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Nisw_08600 cobalamin-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D Nisw_05640 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D Nisw_05650 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D Nisw_05645 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Nisw_05465 ABC transporter permease K09808 lolC_E_F; lipoprotein-releasing system permease protein
D Nisw_05470 ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D Nisw_02495 ABC transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D Nisw_04490 ABC transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D Nisw_02500 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Nisw_04495 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Nisw_02305 sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D Nisw_02060 aquaporin K09866 AQP4; aquaporin-4
D Nisw_02450 hypothetical protein K06188 aqpZ; aquaporin Z
D Nisw_07350 ion transporter K10716 kch; voltage-gated potassium channel
D Nisw_01920 ammonium transporter K03320 amt; ammonium transporter, Amt family
D Nisw_05550 ammonium transporter K03320 amt; ammonium transporter, Amt family
D Nisw_05145 mechanosensitive ion channel K05802 mscK; potassium-dependent mechanosensitive channel
D Nisw_06685 mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel
D Nisw_03400 magnesium transporter K03284 corA; magnesium transporter
D Nisw_07345 corA; magnesium/cobalt transporter CorA K03284 corA; magnesium transporter
D Nisw_04930 CrcB family protein K06199 crcB; fluoride exporter
D Nisw_00590 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Nisw_03250 divalent cation transporter K07238 TC.ZIP; zinc transporter, ZIP family
D Nisw_01910 calcium/sodium antiporter K07301 yrbG; cation:H+ antiporter
D Nisw_04890 peptidase K03316 nhaP; Na+:H+ antiporter
D Nisw_02585 cation:proton antiporter K26735 KEA4_5_6; K+:H+ antiporter
D Nisw_01390 cation:proton antiporter K26730 napA; Na+:H+ antiporter
D Nisw_01955 cation:proton antiporter K26730 napA; Na+:H+ antiporter
D Nisw_03310 cation:proton antiporter K26730 napA; Na+:H+ antiporter
D Nisw_06650 cation:proton antiporter K26730 napA; Na+:H+ antiporter
D Nisw_00955 CBS domain-containing protein K03498 trkH; trk/ktr system potassium uptake protein
D Nisw_05170 hypothetical protein K22736 VIT; vacuolar iron transporter family protein
D Nisw_08810 hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein
D Nisw_07565 sodium-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]
D Nisw_00690 cytochrome C biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
D Nisw_03990 cytochrome C biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
D Nisw_05655 copper resistance protein CopD K14166 ycnJ; copper transport protein
C 02044 Secretion system [BR:niw02044]
D Nisw_08895 type IV secretory pathway protein K07332 flaI; archaeal flagellar protein FlaI
D Nisw_08885 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D Nisw_08890 pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Nisw_00425 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Nisw_08820 dCMP deaminase family protein K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Nisw_02810 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D Nisw_02220 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Nisw_02840 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Nisw_02885 protein translocase SEC61 complex subunit gamma K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Nisw_02290 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19
D Nisw_00905 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_07145 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Nisw_00900 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:niw02042]
D Nisw_00590 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:niw02022]
D Nisw_08160 HAMP domain-containing histidine kinase K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
D Nisw_02970 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_04045 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_05795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_08170 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C 02035 Bacterial motility proteins [BR:niw02035]
D Nisw_02970 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_04045 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_05795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_08170 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Nisw_08895 type IV secretory pathway protein K07332 flaI; archaeal flagellar protein FlaI
D Nisw_08885 type II secretion system F family protein K07333 flaJ; archaeal flagellar protein FlaJ
D Nisw_08890 pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Nisw_00425 peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:niw04812]
D Nisw_03875 amrB; AmmeMemoRadiSam system protein B K06990 MEMO1; MEMO1 family protein
D Nisw_07425 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Nisw_08215 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:niw04147]
D Nisw_03330 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Nisw_02395 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Nisw_08325 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Nisw_01070 elongation factor EF-2 K03234 EEF2; elongation factor 2
D Nisw_04460 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D Nisw_01295 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Nisw_06055 guaB; IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Nisw_02205 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Nisw_04425 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_04955 AAA family ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D Nisw_00315 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Nisw_08370 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Nisw_00545 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_05730 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Nisw_08715 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Nisw_02805 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Nisw_06965 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Nisw_03625 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Nisw_07300 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Nisw_03885 dihydroorotase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Nisw_05055 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_05155 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Nisw_02345 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Nisw_06620 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D Nisw_07445 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Nisw_08805 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:niw02048]
D Nisw_05530 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Nisw_06440 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Nisw_07140 site-specific DNA-methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D Nisw_07425 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Nisw_03360 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Nisw_02620 nucleotide-binding protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
D Nisw_03200 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:niw01504]
D Nisw_07655 lyase K18235 vgb; virginiamycin B lyase [EC:4.2.99.-]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins [BR:niw00536]
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:niw03100]
D Nisw_03680 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_03910 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_06475 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Nisw_02045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_04115 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_06210 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Nisw_00810 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Nisw_03615 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Nisw_04480 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Nisw_02550 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Nisw_02575 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_04600 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_05760 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Nisw_03395 tRNA-His K14226 tRNA-His; tRNA His
D Nisw_06465 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Nisw_02365 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03830 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_04445 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Nisw_03620 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Nisw_04050 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Nisw_03480 tRNA-Met K14230 tRNA-Met; tRNA Met
D Nisw_06095 tRNA-Met K14230 tRNA-Met; tRNA Met
D Nisw_00460 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Nisw_01845 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Nisw_05090 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Nisw_01285 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_03745 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_07080 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Nisw_06445 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_06760 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_07750 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Nisw_06555 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Nisw_04010 tRNA-Val K14237 tRNA-Val; tRNA Val
D Nisw_05350 tRNA-Val K14237 tRNA-Val; tRNA Val
D Nisw_08425 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Nisw_01765 rnpB; RNase P RNA component K01978 rnpB; RNase P catalytic RNA component
D Nisw_04405 ffs; signal recognition particle sRNA K01983 ffs; signal recognition particle 4.5S RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D Nisw_05850 NAD-dependent succinate-semialdehyde dehydrogenase K18601 K18601; aldehyde dehydrogenase [EC:1.2.1.-]
D Nisw_07915 LLM class flavin-dependent oxidoreductase K14728 K14728; phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase [EC:1.2.-.-]
D Nisw_03485 pyrroloquinoline quinone biosynthesis protein PqqC K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11]
D Nisw_04095 npdG; NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D Nisw_08465 msrA; peptide-methionine (S)-S-oxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Nisw_01325 msrB; peptide-methionine (R)-S-oxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D Nisw_02065 thioredoxin-dependent thiol peroxidase K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D Nisw_03555 peroxiredoxin K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D Nisw_02000 ferritin K02217 ftnA; ferritin [EC:1.16.3.2]
D Nisw_03595 ferredoxin--NADP reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D Nisw_03685 ferredoxin--NADP reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D Nisw_01200 arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]
D Nisw_02455 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D Nisw_04360 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D Nisw_03865 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Nisw_07245 dph5; diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D Nisw_04330 hypothetical protein K05303 K05303; O-methyltransferase [EC:2.1.1.-]
D Nisw_04355 glycosyltransferase family 1 protein K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]
D Nisw_00035 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D Nisw_01660 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D Nisw_03220 larB; nickel pincer cofactor biosynthesis protein LarB K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D Nisw_04320 hypothetical protein K22424 E2.7.3.13; glutamine kinase [EC:2.7.3.13]
D Nisw_04300 phosphocholine cytidylyltransferase family protein K01009 E2.7.7.103; L-glutamine-phosphate cytidylyltransferase [EC:2.7.7.103]
D Nisw_00075 CDP-alcohol phosphatidyltransferase family protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D Nisw_06820 TatD family deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D Nisw_05720 carbon-nitrogen hydrolase family protein K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128]
D Nisw_01360 NAD(P)H-hydrate dehydratase K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136]
D Nisw_03205 larE; ATP-dependent sacrificial sulfur transferase LarE K06864 larE; cysteine-dependent pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase [EC:4.4.1.37 4.4.1.45]
D Nisw_03210 larC; nickel pincer cofactor biosynthesis protein LarC K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D Nisw_03295 NAD(P)H-hydrate epimerase K17759 NAXE; NAD(P)H-hydrate epimerase [EC:5.1.99.6]
D Nisw_05365 rtcA; RNA 3'-phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D Nisw_02405 iron-sulfur cluster assembly scaffold protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D Nisw_06340 AAA family ATPase K04748 norQ; nitric oxide reductase NorQ protein
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D Nisw_04775 flippase-like domain-containing protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
D Nisw_01350 DoxX family protein K15977 K15977; putative oxidoreductase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D Nisw_02245 cold-shock protein K03704 cspA; cold shock protein
D Nisw_03160 ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein
D Nisw_03845 RNA-binding protein K04796 RUXX; small nuclear ribonucleoprotein
D Nisw_04515 ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein
C 99974 Translation
D Nisw_07055 DUF655 domain-containing protein K07572 K07572; putative nucleotide binding protein
D Nisw_06220 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor
D Nisw_07895 exonuclease K07577 K07577; putative mRNA 3-end processing factor
D Nisw_07640 RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein
D Nisw_06350 exosome protein K07581 K07581; RNA-binding protein
C 99975 Protein processing
D Nisw_05875 queuine tRNA-ribosyltransferase K07398 K07398; conserved protein with predicted RNA binding PUA domain
C 99976 Replication and repair
D Nisw_07980 single-stranded DNA exonuclease RecJ K07463 K07463; archaea-specific RecJ-like exonuclease
D Nisw_03315 RNA-binding protein K07477 K07477; translin
D Nisw_05725 DNA topoisomerase K07479 yrdD; putative DNA topoisomerase
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D Nisw_02475 inorganic phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family
C 99978 Cell growth
D Nisw_04200 acylneuraminate cytidylyltransferase K07257 spsF; spore coat polysaccharide biosynthesis protein SpsF
D Nisw_05400 DUF552 domain-containing protein K09152 sepF; cell division protein SepF
C 99993 Cell motility
D Nisw_08935 hypothetical protein K23255 pilA; archaeal type IV pilus assembly protein PilA
C 99995 Signaling proteins
D Nisw_05095 serine/threonine protein kinase K07176 K07176; putative serine/threonine protein kinase
D Nisw_05775 DNA-binding protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
C 99994 Others
D Nisw_04390 divalent-cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D Nisw_08175 ATPase K06865 K06865; ATPase
D Nisw_03075 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D Nisw_07135 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D Nisw_01870 tRNA-binding protein K06878 K06878; tRNA-binding protein
D Nisw_07220 erpA; iron-sulfur cluster insertion protein ErpA K15724 erpA; iron-sulfur cluster insertion protein
D Nisw_02415 sufD; Fe-S cluster assembly protein SufD K09014 sufB; Fe-S cluster assembly protein SufB
D Nisw_02420 sufB; Fe-S cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D Nisw_01805 hypothetical protein K07143 K07143; UPF0148 protein
D Nisw_06895 DUF373 family protein K08975 K08975; putative membrane protein
D Nisw_01815 DUF2070 family protein K08979 K08979; putative membrane protein
C 99997 Function unknown
D Nisw_01665 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein
D Nisw_01945 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein
D Nisw_07585 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein
D Nisw_05510 HD domain-containing protein K06885 K06885; uncharacterized protein
D Nisw_07700 thioredoxin domain-containing protein K06888 K06888; uncharacterized protein
D Nisw_01050 ketosteroid isomerase K06893 K06893; uncharacterized protein
D Nisw_08540 CoA-binding protein K06929 K06929; uncharacterized protein
D Nisw_02255 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D Nisw_03115 YkgJ family cysteine cluster protein K06940 K06940; uncharacterized protein
D Nisw_02355 HD domain-containing protein K06950 K06950; uncharacterized protein
D Nisw_08040 metallophosphoesterase K06953 K06953; uncharacterized protein
D Nisw_03780 VOC family protein K06996 K06996; uncharacterized protein
D Nisw_07935 pyridoxamine 5'-phosphate oxidase family protein K07005 K07005; uncharacterized protein
D Nisw_01985 pyridoxamine 5'-phosphate oxidase family protein K07006 K07006; uncharacterized protein
D Nisw_05395 beta-CASP ribonuclease aCPSF1 K07041 K07041; uncharacterized protein
D Nisw_02470 sodium-dependent bicarbonate transport family permease K07086 K07086; uncharacterized protein
D Nisw_08205 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D Nisw_08505 phosphoribosyltransferase K07101 K07101; uncharacterized protein
D Nisw_00005 transcriptional regulator K07108 K07108; uncharacterized protein
D Nisw_04770 SDR family NAD(P)-dependent oxidoreductase K07124 K07124; uncharacterized protein
D Nisw_04580 twitching motility protein PilT K07158 K07158; uncharacterized protein
D Nisw_01180 hypothetical protein K07159 K07159; uncharacterized protein
D Nisw_08195 DUF192 domain-containing protein K09005 K09005; uncharacterized protein
D Nisw_04615 hypothetical protein K09118 K09118; uncharacterized protein
D Nisw_01340 hypothetical protein K09122 K09122; uncharacterized protein
D Nisw_02310 DUF167 domain-containing protein K09131 K09131; uncharacterized protein
D Nisw_03870 TIGR00296 family protein K09141 K09141; uncharacterized protein
D Nisw_00020 hypothetical protein K09143 K09143; uncharacterized protein
D Nisw_07605 hypothetical protein K09143 K09143; uncharacterized protein
D Nisw_06910 DUF424 domain-containing protein K09148 K09148; uncharacterized protein
D Nisw_08620 DUF432 domain-containing protein K09149 K09149; uncharacterized protein
D Nisw_03380 UPF0147 family protein K09721 K09721; uncharacterized protein
D Nisw_04475 DUF354 domain-containing protein K09726 K09726; uncharacterized protein
D Nisw_05115 hypothetical protein K09736 K09736; uncharacterized protein
D Nisw_00710 DUF371 domain-containing protein K09738 K09738; uncharacterized protein
D Nisw_02195 DUF309 domain-containing protein K09763 K09763; uncharacterized protein
D Nisw_04450 hypothetical protein K05967 K05967; uncharacterized protein
D Nisw_06595 hypothetical protein K05967 K05967; uncharacterized protein
D Nisw_02480 DUF47 domain-containing protein K07220 K07220; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: July 17, 2025