+E Transcription factors KO
#
Transcription Factors - Nestor notabilis (Kea)
%
!
AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
D 104401428 JUN; transcription factor AP-1 K04448 JUN; transcription factor AP-1
C AP-1(-like) components, Fos
D 104399165 FOSL2; fos-related antigen 2 K09030 FOSL2; fos-like antigen 2
D 104407826 ATF3; cyclic AMP-dependent transcription factor ATF-3 K09032 ATF3; activating transcription factor 3
D 104410299 JDP2; LOW QUALITY PROTEIN: jun dimerization protein 2 K09033 JDP2; jun dimerization protein 2
D 104410791 basic leucine zipper transcriptional factor ATF-like 3 K09034 BATF; ATF-like basic leucine zipper transcriptional factor
C AP-1(-like) components, Maf
D 104407680 MAFK; transcription factor MafK K09037 MAFF_G_K; transcription factor MAFF/G/K
D 104404017 MAFF; transcription factor MafF K09037 MAFF_G_K; transcription factor MAFF/G/K
D 104400978 MAFG; transcription factor MafG K09037 MAFF_G_K; transcription factor MAFF/G/K
C AP-1(-like) components, NF-E2
D 104403485 NFE2L3; nuclear factor erythroid 2-related factor 3 K09040 NFE2L1_3; nuclear factor erythroid 2-related factor 1/3
D 104409165 NFE2L2; LOW QUALITY PROTEIN: nuclear factor erythroid 2-related factor 2 K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
D 104409184 BACH2; transcription regulator protein BACH2 K09042 BACH; transcription regulator BACH
D 104409895 BACH1; transcription regulator protein BACH1 K09042 BACH; transcription regulator BACH
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
D 104400645 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
D 104407826 ATF3; cyclic AMP-dependent transcription factor ATF-3 K09032 ATF3; activating transcription factor 3
D 104404031 ATF4; cyclic AMP-dependent transcription factor ATF-4 K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
D 104410785 ATF7; cyclic AMP-dependent transcription factor ATF-7 K09045 ATF7; activating transcription factor 7
D 104413376 CREB5; cyclic AMP-responsive element-binding protein 5 K09047 CREB5; cyclic AMP-responsive element-binding protein 5
C CREB
D 104404272 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 104403314 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 104407928 LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 3 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 104413796 LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 4 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 104401736 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 104401189 CREM; cAMP-responsive element modulator isoform X1 K09052 CREM; cAMP response element modulator
D 104409911 ATF1; cyclic AMP-dependent transcription factor ATF-1 isoform X1 K09053 ATF1; activating transcription factor 1
D 104407780 ATF6; cyclic AMP-dependent transcription factor ATF-6 alpha K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
C C/EBP-like factors
D 104410495 CEBPG; CCAAT/enhancer-binding protein gamma K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
C bZIP/PAR
D 104400715 hepatic leukemia factor-like K09057 HLF; hepatic leukemia factor
D 104400695 TEF; thyrotroph embryonic factor K09058 TEF; thyrotrophic embryonic factor
D 104401285 NFIL3; nuclear factor interleukin-3-regulated protein K09059 NFIL3; nuclear factor, interleukin 3 regulated
C Plant bZIP factors
C ZIP only
D 104400430 GCFC2; GC-rich sequence DNA-binding factor 2 K09061 GCF; GC-rich sequence DNA-binding factor
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
D 104402610 TCF3; transcription factor E2-alpha K09063 TCF3; transcription factor E2-alpha
C Myogenic transcription factors
D 104408183 LOW QUALITY PROTEIN: myoblast determination protein 1 homolog K09064 MYOD1; myogenic factor 3
D 104410481 MYOG; myogenin K18483 MYF4; myogenic factor 4 (myogenin)
C Achaete-Scute
D 104404105 ASCL1; achaete-scute homolog 1 K09067 ASCL; achaete-scute complex protein
D 104405484 ASCL3; LOW QUALITY PROTEIN: achaete-scute homolog 3 K09067 ASCL; achaete-scute complex protein
C Tal/Twist/Atonal/Hen, Lymphoid factors
D 104404586 T-cell acute lymphocytic leukemia protein 1 homolog K09068 TAL; T-cell acute lymphocytic leukemia protein
D 104406803 TAL2; T-cell acute lymphocytic leukemia protein 2 K09068 TAL; T-cell acute lymphocytic leukemia protein
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
D 104408664 TWIST2; twist-related protein 2 K09069 TWIST; twist
D 104406489 FERD3L; fer3-like protein K22400 FERD3L; Fer3-like protein
C Tal/Twist/Atonal/Hen, HEN
D 104405867 NHLH1; helix-loop-helix protein 1 K09075 NHLH; nescient helix-loop-helix protein
C Tal/Twist/Atonal/Hen, Mesp
D 104399373 MSGN1; mesogenin-1 K09077 MSGN1; mesogenin 1
C Tal/Twist/Atonal/Hen, Atonal
D 104405673 NEUROD4; neurogenic differentiation factor 4 K09079 NEUROD4; neurogenic differentiation factor 4
D 104405956 NEUROD6; neurogenic differentiation factor 6 K09080 NEUROD6; neurogenic differentiation factor 6
D 104412767 ATOH7; protein atonal homolog 7 K09083 ATOH1_7; atonal protein 1/7
D 104405607 BHLHA9; class A basic helix-loop-helix protein 9 K24145 BHLHA9; class A basic helix-loop-helix protein 9
D 104399736 BHLHA15; class A basic helix-loop-helix protein 15 K08040 BHLHB8; class B basic helix-loop-helix protein 8
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
D 104408003 LOW QUALITY PROTEIN: transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
D 104403600 LOW QUALITY PROTEIN: transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
D 104404346 transcription cofactor HES-6-like K09087 HES2_6_7; hairy and enhancer of split 2/6/7
D 104410439 transcription factor HES-5-like K06055 HES5; hairy and enhancer of split 5
D 104401929 HES5; transcription factor HES-5 K06055 HES5; hairy and enhancer of split 5
D 104413867 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 K09091 HEY; hairy and enhancer of split related with YRPW motif
D 104400583 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 K09091 HEY; hairy and enhancer of split related with YRPW motif
D 104411590 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein K09091 HEY; hairy and enhancer of split related with YRPW motif
D 104406009 BHLHE40; class E basic helix-loop-helix protein 40 K03729 BHLHB2; class B basic helix-loop-helix protein 2
D 104399391 TCFL5; transcription factor-like 5 protein K09092 TCFL5; transcription factor-like 5
C Hairy, Fungal regulators
C Factors with PAS domain
D 104406836 LOW QUALITY PROTEIN: aryl hydrocarbon receptor-like K09093 AHR; aryl hydrocarbon receptor
D 104400627 AHRR; aryl hydrocarbon receptor repressor K09094 AHRR; aryl hydrocarbon receptor repressor
D 104400258 hypoxia-inducible factor 1-alpha-like K08268 HIF1A; hypoxia-inducible factor 1 alpha
D 104411681 EPAS1; endothelial PAS domain-containing protein 1 K09095 HIF2A; hypoxia-inducible factor 2 alpha
D 104406603 ARNT; LOW QUALITY PROTEIN: aryl hydrocarbon receptor nuclear translocator K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
D 104412462 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
D 104406632 NPAS3; neuronal PAS domain-containing protein 3 K09098 NPAS1_3; neuronal PAS domain-containing protein 1/3
D 104403432 NPAS2; neuronal PAS domain-containing protein 2 K09026 NPAS2; neuronal PAS domain-containing protein 2
D 104406266 neuronal PAS domain-containing protein 2-like K09026 NPAS2; neuronal PAS domain-containing protein 2
D 104409500 circadian locomoter output cycles protein kaput K02223 CLOCK; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D 104409675 ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1 K02296 ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1
D 104401096 ARNTL2; aryl hydrocarbon receptor nuclear translocator-like protein 2 K09099 ARNTL2; aryl hydrocarbon receptor nuclear translocator-like protein 2
D 104410451 SIM1; single-minded homolog 1 K09100 SIM; single-minded
D 104400439 single-minded homolog 2-like K09100 SIM; single-minded
C Yabby
C INO
C HLH domain only
D 104401567 LOW QUALITY PROTEIN: DNA-binding protein inhibitor ID-3-A-like K17694 ID3; DNA-binding protein inhibitor ID3
D 104403117 transcription factor COE1 K09103 EBF; early B-cell factor
D 104408586 EBF2; transcription factor COE2 K09103 EBF; early B-cell factor
D 104408701 transcription factor COE3 K09103 EBF; early B-cell factor
D 104404151 CCNDBP1; cyclin-D1-binding protein 1 K21626 CCNDBP1; cyclin-D1-binding protein 1
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
D 104401909 TFEB; LOW QUALITY PROTEIN: transcription factor EB K15590 TFEB; transcription factor EB
D 104403760 TFEC; transcription factor EC K15591 TFEC; transcription factor EC
D 104409955 MITF; microphthalmia-associated transcription factor isoform X1 K09455 MITF; microphthalmia-associated transcription factor
D 104404112 SREBF2; sterol regulatory element-binding protein 2 K09107 SREBP2; sterol regulatory element-binding transcription factor 2
D 104411124 TFAP4; LOW QUALITY PROTEIN: transcription factor AP-4 K09108 TFAP4; transcription factor AP-4
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
D 104402542 MAX; protein max K04453 MAX; Max protein
D 104399703 MLXIP; MLX-interacting protein K09113 MLX; MAX-like protein X
D 104410446 MLX; max-like protein X K09113 MLX; MAX-like protein X
D 104410430 MXD1; max dimerization protein 1 K09114 MXD; MAX dimerization protein
D 104411586 MXI1; max-interacting protein 1 K09114 MXD; MAX dimerization protein
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
D 104406486 NFIA; nuclear factor 1 A-type K09168 NFIA; nuclear factor I/A
D 104408833 NFIB; nuclear factor 1 B-type K09169 NFIB; nuclear factor I/B
C RF-X
D 104413027 RFX2; DNA-binding protein RFX2 K09173 RFX1_2_3; regulatory factor X 1/2/3
D 104402394 RFX3; transcription factor RFX3 isoform X1 K09173 RFX1_2_3; regulatory factor X 1/2/3
D 104404156 RFX4; transcription factor RFX4 K09174 RFX4; regulatory factor X 4
D 104406732 RFX6; DNA-binding protein RFX6 K19521 RFX6; regulatory factor X 6
D 104409511 RFX7; DNA-binding protein RFX7 K09175 RFX7; DNA-binding protein RFX7
C AP-2 (bHSH)
D 104413619 transcription factor AP-2-beta K09176 TFAP2A_B; transcription factor AP-2 alpha/beta
D 104409786 TFAP2C; transcription factor AP-2 gamma K09177 TFAP2C; transcription factor AP-2 gamma
D 104406948 TFAP2D; transcription factor AP-2-delta K09178 TFAP2D; transcription factor AP-2 delta
D 104400425 TFAP2E; transcription factor AP-2-epsilon K09179 TFAP2E; transcription factor AP-2 epsilon
B Zinc finger
C Cys4 thyroid hormone receptor-like
D 104408361 thyroid hormone receptor alpha K05547 THRA; thyroid hormone receptor alpha
D 104404519 thyroid hormone receptor beta isoform X1 K08362 THRB; thyroid hormone receptor beta
D 104413511 retinoic acid receptor alpha-like K08527 RARA; retinoic acid receptor alpha
D 104406124 RARB; retinoic acid receptor beta K08528 RARB; retinoic acid receptor beta
D 104413455 PPARA; peroxisome proliferator-activated receptor alpha K07294 NR1C1; peroxisome proliferator-activated receptor alpha
D 104406730 PPARD; peroxisome proliferator-activated receptor delta K04504 NR1C2; peroxisome proliferator-activated receptor delta
D 104405273 PPARG; peroxisome proliferator-activated receptor gamma K08530 NR1C3; peroxisome proliferator-activated receptor gamma
D 104404518 LOW QUALITY PROTEIN: nuclear receptor subfamily 1 group D member 2-like K08531 NR1D2; nuclear receptor subfamily 1 group D member 2
D 104400513 RORA; nuclear receptor ROR-alpha K08532 NR1F1; RAR-related orphan receptor alpha
D 104412654 RORB; nuclear receptor ROR-beta K08533 NR1F2; RAR-related orphan receptor beta
D 104400667 NR1H3; oxysterols receptor LXR-alpha K08536 NR1H3; liver X receptor alpha
D 104411576 NR1H4; bile acid receptor isoform X1 K08537 NR1H4; farnesoid X receptor
D 104400587 bile acid receptor-like K08538 NR1H5; farnesoid X receptor beta
D 104406365 VDR; vitamin D3 receptor K08539 VDR; vitamin D3 receptor
C Cys4 hepatocyte nuclear factor 4-like
D 104406272 HNF4A; hepatocyte nuclear factor 4-alpha isoform X1 K07292 NR2A1; hepatocyte nuclear factor 4-alpha
D 104406900 HNF4G; hepatocyte nuclear factor 4-gamma K08037 NR2A2; hepatocyte nuclear factor 4-gamma
D 104400925 hepatocyte nuclear factor 4-beta-like isoform X1 K08542 NR2A3; hepatocyte nuclear factor 4-beta
D 104409677 retinoic acid receptor RXR-alpha K08524 RXRA; retinoid X receptor alpha
D 104409157 RXRG; retinoic acid receptor RXR-gamma K08526 RXRG; retinoid X receptor gamma
D 104399893 NR2C1; nuclear receptor subfamily 2 group C member 1 K08543 NR2C1; testicular receptor 2
D 104408004 NR2C2; nuclear receptor subfamily 2 group C member 2 K08544 NR2C2; testicular receptor 4
D 104407996 NR2E3; photoreceptor-specific nuclear receptor K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 104408162 COUP transcription factor 2 K08548 NR2F2; COUP transcription factor 2
C Cys4 estrogen receptor-like
D 104405771 ESR2; estrogen receptor beta K08551 ESR2; estrogen receptor beta
D 104401587 ESRRB; steroid hormone receptor ERR2 isoform X1 K08553 NR3B2; estrogen-related receptor beta
D 104409013 glucocorticoid receptor-like K05771 NR3C1; glucocorticoid receptor
D 104401677 mineralocorticoid receptor-like K08555 NR3C2; mineralocorticoid receptor
C Cys4 nerve growth factor IB-like
D 104403901 LOW QUALITY PROTEIN: nuclear receptor subfamily 4 group A member 2-like K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
D 104412034 LOW QUALITY PROTEIN: nuclear receptor subfamily 4 group A member 3-like K08559 NR4A3; nuclear receptor subfamily 4 group A member 3
C Cys4 Fushi tarazu-F1-like
D 104408276 NR5A1; LOW QUALITY PROTEIN: steroidogenic factor 1 K08560 NR5A1; steroidogenic factor 1
D 104412290 nuclear receptor subfamily 5 group A member 2 K08027 NR5A2; nuclear receptor subfamily 5 group A member 2
C Cys4 germ cell nuclear factor
D 104408095 NR6A1; nuclear receptor subfamily 6 group A member 1 K08561 NR6A1; germ cell nuclear factor
C Cys4 Knirps/DAX1-like
D 104409661 nuclear receptor subfamily 0 group B member 2-like K08563 NR0B2; nuclear receptor subfamily 0 group B member 2
D 104399732 NR0B2; nuclear receptor subfamily 0 group B member 2 K08563 NR0B2; nuclear receptor subfamily 0 group B member 2
C Cys4 GATA-factors
D 104404402 GATA2; endothelial transcription factor GATA-2 K17894 GATA2; GATA-binding protein 2
D 104407626 GATA4; transcription factor GATA-4 K09183 GATA4; GATA-binding protein 4
D 104402102 TRPS1; zinc finger transcription factor Trps1 K22040 TRPS1; atypical GATA-binding protein TRPS1
D 104405217 GATAD1; GATA zinc finger domain-containing protein 1 K23407 GATAD1; GATA zinc finger domain-containing protein 1
D 104405336 GATAD2A; transcriptional repressor p66-alpha K23194 GATAD2; transcriptional repressor p66
D 104410456 GATAD2B; transcriptional repressor p66-beta K23194 GATAD2; transcriptional repressor p66
D 104404894 MTA1; metastasis-associated protein MTA1 K11660 MTA; metastasis-associated protein MTA
D 104409472 metastasis-associated protein MTA3-like K11660 MTA; metastasis-associated protein MTA
D 104401003 DNMT3A; DNA (cytosine-5)-methyltransferase 3A K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 104410223 DNMT3B; DNA (cytosine-5)-methyltransferase 3B K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 104406556 ATRX; LOW QUALITY PROTEIN: transcriptional regulator ATRX K10779 ATRX; transcriptional regulator ATRX
C Cys2His2 SP/KLF family and related proteins
D 104413252 SP2; LOW QUALITY PROTEIN: transcription factor Sp2 K09192 SP2; transcription factor Sp2
D 104406491 SP3; transcription factor Sp3 K09193 SP3; transcription factor Sp3
D 104401022 SP4; transcription factor Sp4 K09194 SP4; transcription factor Sp4
D 104405892 KLF2; Krueppel-like factor 2 K17845 KLF2; krueppel-like factor 2
D 104409046 KLF3; Krueppel-like factor 3 K15605 KLF3; krueppel-like factor 3
D 104408710 KLF5; Krueppel-like factor 5 K09206 KLF5; krueppel-like factor 5
D 104399730 Krueppel-like factor 5 K09206 KLF5; krueppel-like factor 5
D 104409905 Krueppel-like factor 6 K09207 KLF6_7; krueppel-like factor 6/7
D 104402459 KLF7; Krueppel-like factor 7 K09207 KLF6_7; krueppel-like factor 6/7
D 104402691 KLF12; Krueppel-like factor 12 K09205 KLF8_12; krueppel-like factor 8/12
D 104402252 KLF13; Krueppel-like factor 13 K09208 KLF9S; krueppel-like factor 9/13/14/16
D 104403020 KLF10; Krueppel-like factor 10 K09209 KLF10_11; krueppel-like factor 10/11
D 104407846 KLF11; Krueppel-like factor 11 K09209 KLF10_11; krueppel-like factor 10/11
D 104405075 KLF15; Krueppel-like factor 15 K09210 KLF15; krueppel-like factor 15
D 104401434 EGR1; early growth response protein 1 K09203 EGR1; early growth response protein 1
D 104409278 EGR4; LOW QUALITY PROTEIN: early growth response protein 4 K12498 EGR4; early growth response protein 4
D 104411650 zinc finger X-chromosomal protein isoform X1 K27541 ZFX_Y; zinc finger X/Y-chromosomal protein
C Cys2His2 GLI-like
D 104413489 GLI2; zinc finger protein GLI2 K16798 GLI2; zinc finger protein GLI2
D 104406216 GLI3; transcriptional activator GLI3 K06230 GLI3; zinc finger protein GLI3
D 104404745 zinc finger protein GLIS3-like K09232 GLIS1_3; zinc finger protein GLIS1/3
D 104406668 GLIS3; zinc finger protein GLIS3 K09232 GLIS1_3; zinc finger protein GLIS1/3
D 104407623 LOW QUALITY PROTEIN: zinc finger protein ZIC 4-like K09225 ZIC4; zinc finger protein ZIC 4
C Cys2His2 Snail
D 104403931 protein snail homolog Sna K05707 SNAI1; snail 1
D 104401346 SNAI2; zinc finger protein SNAI2 K05706 SNAI2; snail 2
C Cys2His2 BTB-ZF factors
D 104401277 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
D 104410523 ZBTB2; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 2 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
D 104401098 ZBTB5; zinc finger and BTB domain-containing protein 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
D 104399588 ZBTB6; zinc finger and BTB domain-containing protein 6 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
D 104411192 ZBTB7A; zinc finger and BTB domain-containing protein 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
D 104402436 ZBTB7C; zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
D 104402930 zinc finger and BTB domain-containing protein 8A-like K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
D 104409416 ZBTB8B; zinc finger and BTB domain-containing protein 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
D 104399519 ZBTB8A; zinc finger and BTB domain-containing protein 8A isoform X1 K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
D 104403385 ZBTB10; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 10 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
D 104399044 ZBTB11; zinc finger and BTB domain-containing protein 11 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
D 104411399 ZBTB14; zinc finger and BTB domain-containing protein 14 K24804 ZBTB14; zinc finger and BTB domain-containing protein 14
D 104403534 ZBTB17; zinc finger and BTB domain-containing protein 17 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
D 104408942 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 20-like K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
D 104404001 ZBTB21; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 21 K24805 ZBTB21; zinc finger and BTB domain-containing protein 21
D 104403293 ZBTB24; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 24 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
D 104399057 ZBTB25; zinc finger and BTB domain-containing protein 25 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
D 104401330 ZBTB26; zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
D 104399123 ZBTB33; transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
D 104404353 ZBTB34; zinc finger and BTB domain-containing protein 34 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
D 104400874 ZNF131; zinc finger protein 131 K24806 ZBTB35; zinc finger and BTB domain-containing protein 35
D 104401974 ZBTB37; zinc finger and BTB domain-containing protein 37 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
D 104408706 ZBTB38; zinc finger and BTB domain-containing protein 38 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
D 104410026 ZBTB39; zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
D 104411002 ZBTB40; zinc finger and BTB domain-containing protein 40 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
D 104399458 ZBTB41; zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
D 104399614 ZBTB43; zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
D 104410703 ZBTB44; zinc finger and BTB domain-containing protein 44 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
D 104404671 ZBTB46; zinc finger and BTB domain-containing protein 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
D 104407628 ZBTB47; zinc finger and BTB domain-containing protein 47 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
D 104399421 ZBTB49; zinc finger and BTB domain-containing protein 49 K24807 ZBTB49; zinc finger and BTB domain-containing protein 49
D 104404881 ZBTB18; zinc finger and BTB domain-containing protein 18 isoform X1 K23196 ZBTB18_42; zinc finger and BTB domain-containing protein 18/42
D 104399115 zinc finger and BTB domain-containing protein 18.2-like K23196 ZBTB18_42; zinc finger and BTB domain-containing protein 18/42
D 104411861 GZF1; GDNF-inducible zinc finger protein 1 K22402 GZF1; GDNF-inducible zinc finger protein 1
D 104400392 BCL6; B-cell lymphoma 6 protein K15618 BCL6; B-cell lymphoma 6 protein
D 104407631 VEZF1; vascular endothelial zinc finger 1 K26610 VEZF1; vascular endothelial zinc finger 1
D 104413336 HIC2; hypermethylated in cancer 2 protein K24384 HIC; hypermethylated in cancer protein
D 104405192 MYNN; myoneurin isoform X1 K24385 MYNN; myoneurin
C Cys2His2 BED
D 104408849 ZBED1; zinc finger BED domain-containing protein 1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
D 104403863 ZBED4; zinc finger BED domain-containing protein 4 K24640 ZBED4; zinc finger BED domain-containing protein 4
C Cys2His2 PRDM
D 104409773 LOW QUALITY PROTEIN: PR domain zinc finger protein 1-like K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-]
D 104405572 PRDM2; PR domain zinc finger protein 2 K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
D 104402745 MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X1 K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
D 104409765 PR domain zinc finger protein 4-like K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
D 104399940 PR domain zinc finger protein 5-like K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 104408128 PRDM6; putative histone-lysine N-methyltransferase PRDM6 K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
D 104412906 ZNF488; zinc finger protein 488 K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
D 104413544 PRDM10; PR domain zinc finger protein 10 isoform X1 K24643 PRDM10; PR domain zinc finger protein 10 [EC:2.1.1.-]
D 104402755 PRDM11; PR domain-containing protein 11 K24644 PRDM11; PR domain zinc finger protein 11 [EC:2.1.1.-]
D 104409965 PRDM16; PR domain zinc finger protein 16 K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
D 104406172 OSR1; protein odd-skipped-related 1 K09215 OSR; odd-skipped
D 104401089 OVOL2; transcription factor Ovo-like 2 K09216 OVOL; ovo
D 104403379 IKZF1; DNA-binding protein Ikaros K09220 IKZF; IKAROS family zinc finger protein
D 104404609 IKZF2; zinc finger protein Helios K09220 IKZF; IKAROS family zinc finger protein
D 104400982 IKZF5; zinc finger protein Pegasus K09220 IKZF; IKAROS family zinc finger protein
D 104402679 IKZF3; zinc finger protein Aiolos K09220 IKZF; IKAROS family zinc finger protein
D 104404393 REST; RE1-silencing transcription factor K09222 REST; RE1-silencing transcription factor
D 104413762 GFI1B; zinc finger protein Gfi-1b K09223 GFI1; growth factor independent 1
D 104403479 TSHZ1; teashirt homolog 1 K09236 TSHZ; teashirt
D 104408252 TSHZ2; teashirt homolog 2 K09236 TSHZ; teashirt
D 104406279 TSHZ3; teashirt homolog 3 K09236 TSHZ; teashirt
D 104412047 HIVEP1; zinc finger protein 40 K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
D 104408743 HIVEP2; transcription factor HIVEP2 isoform X1 K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
D 104413356 AEBP2; zinc finger protein AEBP2 K17452 AEBP2; zinc finger protein AEBP2
D 104412955 PLAG1; zinc finger protein PLAG1 K19484 PLAG1; zinc finger protein PLAG1
D 104408787 PLAGL1; zinc finger protein PLAGL1 K19485 PLAGL1; zinc finger protein PLAGL1
D 104406316 PLAGL2; zinc finger protein PLAGL2 K19486 PLAGL2; zinc finger protein PLAGL2
D 104409665 RREB1; ras-responsive element-binding protein 1 K20210 RREB1; ras-responsive element-binding protein 1
D 104410985 LOW QUALITY PROTEIN: B-cell lymphoma/leukemia 11A-like K22045 BCL11A; B-cell lymphoma/leukemia 11A
D 104413779 BCL11B; B-cell lymphoma/leukemia 11B K22046 BCL11B; B-cell lymphoma/leukemia 11B
D 104399372 E4F1; transcription factor E4F1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
D 104408472 CTCF; transcriptional repressor CTCF isoform X1 K23195 CTCF; transcriptional repressor CTCF
D 104402357 LOW QUALITY PROTEIN: transcriptional repressor CTCFL-like K23195 CTCF; transcriptional repressor CTCF
D 104399665 MTF1; metal regulatory transcription factor 1 K23317 MTF1; metal regulatory transcription factor 1
D 104407899 BNC1; zinc finger protein basonuclin-1 K24146 BNC; zinc finger protein basonuclin
D 104405338 BNC2; LOW QUALITY PROTEIN: zinc finger protein basonuclin-2 K24146 BNC; zinc finger protein basonuclin
D 104412926 GTF3A; transcription factor IIIA K09191 GTF3A; general transcription factor IIIA
D 104408189 RPA1; replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
D 104401532 ZNF142; LOW QUALITY PROTEIN: zinc finger protein 142 K24851 ZNF142; zinc finger protein 142
D 104399865 ZNF148; zinc finger protein 148 K24370 ZNF148; zinc finger protein 148
D 104412629 ZNF292; zinc finger protein 292 K26728 ZNF292; zinc finger protein 292
D 104408288 ZNF335; LOW QUALITY PROTEIN: zinc finger protein 335 K24371 ZNF335; zinc finger protein 335
D 104402965 ZNF341; zinc finger protein 341 K24852 ZNF341; zinc finger protein 341
D 104413327 ZNF384; zinc finger protein 384 K23480 ZNF362_384; zinc finger protein 362/384
D 104410656 ZNF407; zinc finger protein 407 K26729 ZNF407; Zinc finger protein 407
D 104405374 ZNF410; zinc finger protein 410 K25858 ZNF410; zinc finger protein 410
D 104405932 ZNF423; zinc finger protein 423 K22870 ZNF423; zinc finger protein 423
D 104399476 ZNF462; zinc finger protein 462 K24853 ZNF462; zinc finger protein 462
D 104403233 zinc finger protein 516-like K22411 ZNF516; zinc finger protein 516
D 104408228 zinc finger protein 516-like K22411 ZNF516; zinc finger protein 516
D 104404480 ZNF521; zinc finger protein 521 K24916 ZNF521; zinc finger protein 521
D 104411032 ZNF536; zinc finger protein 536 K27242 ZNF536; zinc finger protein 536
D 104412393 ZNF638; zinc finger protein 638 K24692 ZNF638; zinc finger protein 638
D 104407285 ZNF644; zinc finger protein 644 isoform X1 K24374 ZNF644; zinc finger protein 644
D 104410373 ZNF687; LOW QUALITY PROTEIN: zinc finger protein 687 K24375 ZNF687; zinc finger protein 687
D 104407670 ZNF711; zinc finger protein 711 isoform X1 K24376 ZNF711; zinc finger protein 711
D 104399010 ZNF750; zinc finger protein 750 K24377 ZNF750; zinc finger protein 750
D 104403197 ZNF777; zinc finger protein 777 K09228 KRAB; KRAB domain-containing zinc finger protein
D 104401355 zinc finger protein 271-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 104404343 zinc finger protein 497-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 104402588 zinc finger protein 300-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 104400703 LOW QUALITY PROTEIN: fez family zinc finger protein 1-like K24502 FEZF; Fez family zinc finger protein
D 104403969 CASZ1; zinc finger protein castor homolog 1 K25209 CASZ1; zinc finger protein castor
D 104409672 LOW QUALITY PROTEIN: histone H4 transcription factor-like K25794 HINFP; histone H4 transcription factor
C Cys2HisCys zinc factors
D 104411889 MYT1; myelin transcription factor 1 K23192 MYT1; myelin transcription factor 1
D 104402820 MYT1L; myelin transcription factor 1-like protein K23193 MYT1L; myelin transcription factor 1-like protein
D 104413260 ST18; suppression of tumorigenicity 18 protein K24386 ST18; suppression of tumorigenicity 18 protein
D 104410674 ZFPM2; zinc finger protein ZFPM2 K17442 ZFPM2; zinc finger protein ZFPM2
D 104404523 KAT7; histone acetyltransferase KAT7 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 104403751 KAT6A; histone acetyltransferase KAT6A K11305 MYST3; histone acetyltransferase MYST3 [EC:2.3.1.48]
D 104405535 KAT6B; histone acetyltransferase KAT6B K11306 MYST4; histone acetyltransferase MYST4 [EC:2.3.1.48]
D 104408439 L3MBTL3; lethal(3)malignant brain tumor-like protein 3 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 104401398 L3MBTL1; lethal(3)malignant brain tumor-like protein 1 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 104402559 L3MBTL2; lethal(3)malignant brain tumor-like protein 2 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 104407229 lethal(3)malignant brain tumor-like protein 4 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
D 104406426 LYAR; cell growth-regulating nucleolar protein K15263 LYER; cell growth-regulating nucleolar protein
C Cys3His zinc factors
D 104400447 roquin-1-like K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 104404939 RC3H2; roquin-2 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 104410491 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
C Cys2CysHis zinc factors
D 104412947 THAP1; THAP domain-containing protein 1 K23203 THAP1_3; THAP domain-containing protein 1/3
D 104401652 THAP5; THAP domain-containing protein 5 K23206 THAP5_8; THAP domain-containing protein 5/8
C CXXC CpG-binding proteins
D 104406956 LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2A-like K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
D 104407558 CXXC5; CXXC-type zinc finger protein 5 K22760 CXXC5; CXXC-type zinc finger protein 5
D 104401976 TET1; methylcytosine dioxygenase TET1 K13097 TET1; methylcytosine dioxygenase [EC:1.14.11.80]
D 104404004 TET2; methylcytosine dioxygenase TET2 K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D 104407706 methylcytosine dioxygenase TET3-like K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D 104404978 DNMT1; DNA (cytosine-5)-methyltransferase 1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 104408937 LOW QUALITY PROTEIN: lysine-specific demethylase 2A-like K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
D 104402807 KDM2B; lysine-specific demethylase 2B K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
D 104408035 PHF6; PHD finger protein 6 isoform X1 K23310 PHF6; PHD finger protein 6
D 104408302 PHF19; PHD finger protein 19 K11486 PHF19; PHD finger protein 19
D 104410166 MTF2; metal-response element-binding transcription factor 2 isoform X1 K11485 MTF2; metal regulatory transcription factor 2
D 104408491 NFX1; transcriptional repressor NF-X1 K12236 NFX1; transcriptional repressor NF-X1
D 104401119 CNBP; cellular nucleic acid-binding protein isoform X1 K09250 CNBP; cellular nucleic acid-binding protein
D 104400450 ZC4H2; zinc finger C4H2 domain-containing protein K24369 ZC4H2; zinc finger C4H2 domain-contaning protein
D 104405152 TCF20; transcription factor 20 K24769 TCF20; transcription factor 20
B Helix-turn-helix
C Homeo domain ANTP: HOXL
D 104399087 HOXB9; LOW QUALITY PROTEIN: homeobox protein Hox-B9 K09294 HOX_9; homeobox protein HoxB/C/D9
D 104404231 HOXA10; LOW QUALITY PROTEIN: homeobox protein Hox-A10 K17443 HOXA10; homrobox protein Hox-A10
D 104401006 HOXC10; homeobox protein Hox-C10 K17444 HOXC10; homrobox protein Hox-C10
D 104399285 HOXD10; homeobox protein Hox-D10 K09295 HOXD10; homrobox protein Hox-D10
D 104409325 HOXC11; homeobox protein Hox-C11 K09296 HOX_11; homeobox protein HoxC/D11
D 104400611 homeobox protein Hox-D11 K09296 HOX_11; homeobox protein HoxC/D11
D 104401528 HOXD12; homeobox protein Hox-D12 K09297 HOX_12; homeobox protein HoxC/D12
D 104406324 HOXC12; homeobox protein Hox-C12 K09297 HOX_12; homeobox protein HoxC/D12
D 104413620 HOXA2; homeobox protein Hox-A2 K09302 HOX_2; homeobox protein HoxA/B2
D 104401240 HOXA3; homeobox protein Hox-A3 K09303 HOX_3; homeobox protein HoxA/B/D3
D 104400462 HOXB3; homeobox protein Hox-B3 isoform X1 K09303 HOX_3; homeobox protein HoxA/B/D3
D 104401475 LOW QUALITY PROTEIN: homeobox protein Hox-C4-like K09304 HOX_4; homeobox protein HoxA/B/C/D4
D 104401599 LOW QUALITY PROTEIN: homeobox protein Hox-D4-like K09304 HOX_4; homeobox protein HoxA/B/C/D4
D 104413879 HOXA5; LOW QUALITY PROTEIN: homeobox protein Hox-A5 K09305 HOX_5; homeobox protein HoxA/B/C5
D 104411139 HOXC5; homeobox protein Hox-C5 K09305 HOX_5; homeobox protein HoxA/B/C5
D 104399733 HOXC6; homeobox protein Hox-C6 K09306 HOX_6; homeobox protein HoxA/B/C6
D 104402622 HOXA7; homeobox protein Hox-A7 K09307 HOX_7; homeobox protein HoxA/B7
D 104399319 HOXC8; homeobox protein Hox-C8 K09308 HOX_8; homeobox protein HoxB/C/D8
D 104406058 HOXB8; homeobox protein Hox-B8 isoform X1 K09308 HOX_8; homeobox protein HoxB/C/D8
D 104406903 HOXD8; homeobox protein Hox-D8 K09308 HOX_8; homeobox protein HoxB/C/D8
D 104408237 homeobox protein CDX-1 K09312 CDX1_4; homeobox protein CDX1/4
D 104411771 LOW QUALITY PROTEIN: homeobox protein CDX-4-like K09312 CDX1_4; homeobox protein CDX1/4
D 104411772 homeobox protein CDX-1-like K09312 CDX1_4; homeobox protein CDX1/4
D 104411875 EVX2; homeobox even-skipped homolog protein 2 K09320 EVX; homeobox even-skipped homolog protein
D 104403634 homeobox protein MOX-2-like K09322 MEOX; homeobox protein MOX
D 104406052 homeobox protein MOX-2 K09322 MEOX; homeobox protein MOX
D 104400852 MEOX1; homeobox protein MOX-1 K09322 MEOX; homeobox protein MOX
C Homeo domain ANTP: NKL
D 104401074 NKX2-1; homeobox protein Nkx-2.1 K09342 NKX2-1; homeobox protein Nkx-2.1
D 104407963 homeobox protein Nkx-2.6-like K09346 NKX2-6; homeobox protein Nkx-2.6
D 104407961 homeobox protein Nkx-3.1-like K09348 NKX3-1; homeobox protein Nkx-3.1
D 104404341 DLX1; homeobox protein DLX-1 K09314 DLX1_4_6; homeobox protein DLX1/4/6
D 104406996 DLX6; homeobox protein DLX-6 K09314 DLX1_4_6; homeobox protein DLX1/4/6
D 104408327 DLX3; homeobox protein DLX-3 K09315 DLX3; homeobox protein DLX3
D 104402174 homeobox protein GHOX-7 K09341 MSX; homeobox protein MSX
D 104401448 MSX2; homeobox protein MSX-2 K09341 MSX; homeobox protein MSX
D 104407326 BARX2; homeobox protein BarH-like 2 K09361 BARX; BarH-like homeobox
D 104411155 BSX; brain-specific homeobox protein homolog K24874 BSX; brain-specific homeobox protein
D 104400433 DBX2; homeobox protein DBX2 K24875 DBX; homeobox protein DBX
D 104406733 homeobox protein DBX1-like K24875 DBX; homeobox protein DBX
D 104402292 HHEX; hematopoietically-expressed homeobox protein HHEX K24876 NOTO; homeobox protein notochord
D 104402565 VAX2; ventral anterior homeobox 2 K24876 NOTO; homeobox protein notochord
C Homeo domain Paired-related
D 104400128 GSC2; homeobox protein goosecoid-2 K09325 GSCL; homeobox protein goosecoid-like
D 104409349 OTX2; homeobox protein OTX2 K18490 OTX2; homeobox protein OTX2
D 104401824 PRRX2; paired mesoderm homeobox protein 2 K09329 PRRX; paired mesoderm homeobox protein
D 104406934 PRRX1; paired mesoderm homeobox protein 1 K09329 PRRX; paired mesoderm homeobox protein
D 104410926 ALX homeobox protein 1-like K09334 ALX1; ALX homeobox protein 1
D 104412984 VSX1; visual system homeobox 1 K09335 VSX1; visual system homeobox protein 1
D 104406018 pituitary homeobox 3 K09357 PITX3; paired-like homeodomain transcription factor 3
D 104412476 HESX1; homeobox expressed in ES cells 1 K09354 HESX1; homeobox protein expressed in ES cells 1
D 104412837 DMBX1; diencephalon/mesencephalon homeobox protein 1 isoform X1 K24893 DMBX1; diencephalon/mesencephalon homeobox protein 1
D 104404460 DRGX; dorsal root ganglia homeobox protein K24895 DRGX; dorsal root ganglia homeobox protein
D 104413178 HOPX; homeodomain-only protein K24897 HOPX; homeodomain-only protein
D 104405016 paired box protein Pax-2-A-like K15608 PAX2; paired box protein 2
D 104407318 PAX3; paired box protein Pax-3 K09381 PAX3_7; paired box protein 3/7
D 104405769 PAX6; paired box protein Pax-6 isoform X1 K08031 PAX6; paired box protein 6
C Homeo domain LIM
D 104401035 ISL1; insulin gene enhancer protein ISL-1 K09370 ISL1; insulin gene enhancer protein ISL-1
D 104408047 LMX1A; LIM homeobox transcription factor 1-alpha K09371 LMX1; LIM homeobox transcription factor 1
D 104408626 LMX1B; LIM homeobox transcription factor 1-beta K09371 LMX1; LIM homeobox transcription factor 1
D 104404685 LIM/homeobox protein LMX-1.2-like K09371 LMX1; LIM homeobox transcription factor 1
D 104408725 LHX8; LIM/homeobox protein Lhx8 K09375 LHX6_8; LIM homeobox protein 6/8
D 104413502 CSRP1; cysteine and glycine-rich protein 1 K09377 CSRP; cysteine and glycine-rich protein
D 104409085 CSRP3; cysteine and glycine-rich protein 3 K09377 CSRP; cysteine and glycine-rich protein
D 104405637 CSRP2; cysteine and glycine-rich protein 2 isoform X1 K09377 CSRP; cysteine and glycine-rich protein
C Homeo domain POU
D 104412015 POU1F1; pituitary-specific positive transcription factor 1 isoform X1 K09363 POU1F; POU domain transcription factor, class 1
D 104403356 POU2F1; POU domain, class 2, transcription factor 1 isoform X1 K09364 POU2F; POU domain transcription factor, class 2
D 104406028 POU2F3; POU domain, class 2, transcription factor 3 K09364 POU2F; POU domain transcription factor, class 2
D 104401687 POU6F2; POU domain, class 6, transcription factor 2 K09368 POU6F; POU domain transcription factor, class 6
D 104409877 HDX; highly divergent homeobox K24884 HDX; highly divergent homeobox
D 104412578 HNF1A; hepatocyte nuclear factor 1-alpha K08036 TCF1; transcription factor 1, hepatocyte nuclear factor 1-alpha
D 104410638 hepatocyte nuclear factor 1-beta-like K08034 TCF2; transcription factor 2, hepatocyte nuclear factor 1-beta
D 104411371 HMBOX1; homeobox-containing protein 1 K24885 HMBOX1; homeobox-containing protein 1
C Homeo domain SINE
D 104399453 SIX4; homeobox protein SIX4 K15615 SIX4; homeobox protein SIX4
C Homeo domain ZF
D 104406273 LOW QUALITY PROTEIN: zinc finger homeobox protein 3-like K09378 ZFHX3; zinc finger homeobox protein 3
D 104408512 ZFHX4; zinc finger homeobox protein 4 K09380 ZFHX4; zinc finger homeobox protein 4
D 104402688 ZEB1; zinc finger E-box-binding homeobox 1 K09299 ZEB1; zinc finger homeobox protein 1
D 104406466 ZEB2; zinc finger E-box-binding homeobox 2 K23560 ZEB2; zinc finger homeobox protein 2
D 104405473 ADNP; activity-dependent neuroprotector homeobox protein K22591 ADNP; activity-dependent neuroprotector homeobox protein
D 104400752 ADNP2; ADNP homeobox protein 2 K24878 ADNP2; activity-dependent neuroprotector homeobox protein 2
D 104405409 ZHX1; zinc fingers and homeoboxes protein 1 K24879 ZHX1; zinc fingers and homeoboxes protein 1
D 104412695 ZHX2; zinc fingers and homeoboxes protein 2 K24880 ZHX2; zinc fingers and homeoboxes protein 2
C Homeo domain CUT
D 104412212 homeobox protein cut-like 2 K09313 CUTL; homeobox protein cut-like
D 104412584 LOW QUALITY PROTEIN: homeobox protein cut-like 1 K09313 CUTL; homeobox protein cut-like
D 104408070 SATB1; DNA-binding protein SATB1 K23225 SATB1; DNA-binding protein SATB1
D 104407092 SATB2; DNA-binding protein SATB2 K23226 SATB2; DNA-binding protein SATB2
C Homeo domain PROS
D 104408913 PROX1; prospero homeobox protein 1 K20211 PROX1; prospero homeobox 1
D 104408250 PROX2; prospero homeobox protein 2 K20212 PROX2; prospero homeobox 2
C Homeo domain TALE
D 104412529 pre-B-cell leukemia transcription factor 1 K09355 PBX1; pre-B-cell leukemia transcription factor 1
D 104408860 LOW QUALITY PROTEIN: pre-B-cell leukemia transcription factor 3-like K15610 PBX3; pre-B-cell leukemia transcription factor 3
D 104411900 pre-B-cell leukemia transcription factor 3-like K15611 PBX4; pre-B-cell leukemia transcription factor 4
D 104402477 homeobox protein Meis2-like K16670 MEIS2; homeobox protein Meis2
D 104411568 TGIF1; homeobox protein TGIF1 K19383 TGIF1; homeobox protein TGIF1
D 104410810 IRX1; iroquois-class homeodomain protein IRX-1 K24889 IRX; iroquois-class homeodomain protein IRX
D 104407510 MKX; homeobox protein Mohawk K24890 MKX; homeobox protein Mohawk
D 104408991 PKNOX1; homeobox protein PKNOX1 K24891 PKNOX; homeobox protein PKNOX
C Homeo domain other
C Fork head/winged helix developmental regulators
D 104409025 FOXG1; forkhead box protein G1 K09385 FOXG; forkhead box protein G
D 104403094 forkhead box protein N3-like K09407 FOXN; forkhead box protein N
D 104412411 FOXN1; forkhead box protein N1 K09407 FOXN; forkhead box protein N
D 104412558 FOXN4; forkhead box protein N4 K09407 FOXN; forkhead box protein N
D 104411026 FOXN2; forkhead box protein N2 isoform X1 K09407 FOXN; forkhead box protein N
C Fork head/winged helix tissue-specific regulators
D 104410769 FOXA1; hepatocyte nuclear factor 3-alpha K09387 FOXA1; forkhead box protein A1, hepatocyte nuclear factor 3-alpha
D 104411841 FOXJ1; forkhead box protein J1 K09402 FOXJ1; forkhead box protein J1
C Fork head/winged helix cell cycle-controlling factors, E2F
D 104403541 LOW QUALITY PROTEIN: transcription factor E2F2-like K09389 E2F2; transcription factor E2F2
D 104413196 E2F3; transcription factor E2F3 K06620 E2F3; transcription factor E2F3
D 104400312 E2F5; transcription factor E2F5 K04682 E2F4_5; transcription factor E2F4/5
D 104402510 E2F4; transcription factor E2F4 K04682 E2F4_5; transcription factor E2F4/5
D 104401027 E2F6; transcription factor E2F6 K09390 E2F6; transcription factor E2F6
D 104409084 E2F8; LOW QUALITY PROTEIN: transcription factor E2F8 K09391 E2F7_8; transcription factor E2F7/8
D 104405920 E2F7; transcription factor E2F7 K09391 E2F7_8; transcription factor E2F7/8
C Fork head/winged helix cell cycle-controlling factors, DP
D 104400570 TFDP1; transcription factor Dp-1 K04683 TFDP1; transcription factor Dp-1
D 104412967 TFDP2; transcription factor Dp-2 K09392 TFDP2; transcription factor Dp-2
C Fork head/winged helix other regulators
D 104407589 FOXI1; forkhead box protein I1 isoform X1 K09401 FOXI; forkhead box protein I
D 104411234 FOXJ2; forkhead box protein J2 isoform X1 K09403 FOXJ2_3; forkhead box protein J2/3
D 104409852 FOXK1; forkhead box protein K1 K09404 FOXK; forkhead box protein K
D 104406833 FOXK2; forkhead box protein K2 K09404 FOXK; forkhead box protein K
D 104409185 FOXM1; forkhead box protein M1 K09406 FOXM; forkhead box protein M
D 104401703 FOXO1; forkhead box protein O1 K07201 FOXO1; forkhead box protein O1
D 104403248 FOXO3; forkhead box protein O3 K09408 FOXO3; forkhead box protein O3
D 104402193 FOXO4; forkhead box protein O4 K12358 FOXO4; forkhead box protein O4
D 104406291 LOW QUALITY PROTEIN: forkhead box protein O6-like K17847 FOXO6; forkhead box protein O6
D 104407579 FOXP1; forkhead box protein P1 K23582 FOXP1; forkhead box protein P1
D 104408698 LOW QUALITY PROTEIN: forkhead box protein P2-like K09409 FOXP2_4; forkhead box protein P2/4
D 104405246 LOW QUALITY PROTEIN: forkhead box protein P4-like K09409 FOXP2_4; forkhead box protein P2/4
D 104401407 forkhead box protein N5-like K26215 FOXR; forkhead box protein R
C Heat shock factors
D 104399911 HSF2; heat shock factor protein 2 K09415 HSF2; heat shock transcription factor 2
D 104401517 heat shock factor protein 3-like K09416 HSF3; heat shock transcription factor 3
D 104401821 heat shock factor protein 4-like K09417 HSF4; heat shock transcription factor 4
C Tryptophan clusters Myb, Myb-factors
D 104402359 LOW QUALITY PROTEIN: transcriptional activator Myb-like K09420 MYB; transcriptional activator Myb
D 104405050 MYBL1; myb-related protein A K09421 MYBL1; myb-related protein A
D 104406578 MYBL2; myb-related protein B K21769 MYBL2; myb-related protein B
C Tryptophan clusters Myb, Myb-like factors
D 104408068 SNAPC4; snRNA-activating protein complex subunit 4 K09453 SNAPC4; snRNA-activating protein complex subunit 4
D 104400018 DMTF1; cyclin-D-binding Myb-like transcription factor 1 K21625 DMTF1; cyclin-D-binding Myb-like transcription factor 1
C Tryptophan clusters Ets-type
D 104409417 ELF2; LOW QUALITY PROTEIN: ETS-related transcription factor Elf-2 K09428 ELF1_2_4; E74-like factor 1/2/4
D 104411278 ELF1; ETS-related transcription factor Elf-1 isoform X1 K09428 ELF1_2_4; E74-like factor 1/2/4
D 104412764 ELF3; ETS-related transcription factor Elf-3 K09429 K09429; E74-like factor 3
D 104408196 EHF; ETS homologous factor K17102 EHF; ETS homologous factor
D 104402100 ELK3; ETS domain-containing protein Elk-3 K09430 ELK3; ETS domain-containing protein Elk-3 (SRF accessory protein 2)
D 104402628 ELK4; ETS domain-containing protein Elk-4 K04376 ELK4; ETS domain-containing protein Elk-4
D 104412999 ETV5; ETS translocation variant 5 K09431 ETV1; ets translocation variant 1
D 104413747 ETV1; ETS translocation variant 1 K09431 ETV1; ets translocation variant 1
D 104405957 ETV4; ETS translocation variant 4 K15592 ETV4; ets translocation variant 4
D 104405418 ETV7; transcription factor ETV7 K03211 ETV6_7; ETS translocation variant 6/7
D 104406867 ETV6; transcription factor ETV6 K03211 ETV6_7; ETS translocation variant 6/7
D 104402018 ETS1; protein C-ets-1 K02678 ETS1; C-ets-1
D 104410473 ETS2; protein C-ets-2 K21932 ETS2; C-ets-2
D 104408798 ERG; transcriptional regulator ERG isoform X1 K09435 ERG; transcriptional regulator ERG
D 104412445 FLI1; Friend leukemia integration 1 transcription factor K09436 FLI1; friend leukemia integration 1 transcription factor
D 104412673 FEV; protein FEV K09437 FEV; ETS oncogene family protein FEV
D 104412408 SPI1; transcription factor PU.1 isoform X1 K09438 SPI1; transcription factor PU.1
D 104409857 SPIC; transcription factor Spi-C K09440 SPIC; transcription factor Spi-C
D 104412993 GABPA; GA-binding protein alpha chain K09441 GABPA; GA-binding protein transcription factor, alpha
D 104413841 SPDEF; LOW QUALITY PROTEIN: SAM pointed domain-containing Ets transcription factor K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
C Tryptophan clusters interferon-regulating factors
D 104402929 IRF1; interferon regulatory factor 1 K09444 IRF1; interferon regulatory factor 1
D 104400678 IRF2; interferon regulatory factor 2 K10153 IRF2; interferon regulatory factor 2
D 104409753 IRF4; interferon regulatory factor 4 K09445 IRF4; interferon regulatory factor 4
D 104409387 IRF6; interferon regulatory factor 6 K10154 IRF6; interferon regulatory factor 6
D 104412949 IRF8; interferon regulatory factor 8 K10155 IRF8; interferon regulatory factor 8
C TEA domain
D 104404763 TEAD1; transcriptional enhancer factor TEF-1 isoform X1 K09448 TEAD; transcriptional enhancer factor
D 104409377 TEAD3; LOW QUALITY PROTEIN: transcriptional enhancer factor TEF-5 K09448 TEAD; transcriptional enhancer factor
D 104406512 TEAD4; transcriptional enhancer factor TEF-3 K09448 TEAD; transcriptional enhancer factor
C ARID
D 104413621 ARID1B; AT-rich interactive domain-containing protein 1B K11653 ARID1; AT-rich interactive domain-containing protein 1
D 104411935 LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1A-like K11653 ARID1; AT-rich interactive domain-containing protein 1
D 104407509 ARID2; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 2 K11765 ARID2; AT-rich interactive domain-containing protein 2
D 104403898 AT-rich interactive domain-containing protein 3A-like K25856 ARID3; AT-rich interactive domain-containing protein 3
D 104402482 ARID3B; AT-rich interactive domain-containing protein 3B K25856 ARID3; AT-rich interactive domain-containing protein 3
D 104399973 ARID4A; AT-rich interactive domain-containing protein 4A K19194 ARID4A; AT-rich interactive domain-containing protein 4A
D 104403599 ARID4B; AT-rich interactive domain-containing protein 4B K19195 ARID4B; AT-rich interactive domain-containing protein 4B
D 104407709 ARID5B; AT-rich interactive domain-containing protein 5B K25857 ARID5; AT-rich interactive domain-containing protein 5
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
D 104401714 NFKB1; nuclear factor NF-kappa-B p105 subunit K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
D 104412934 LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p100 subunit-like K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
D 104411088 proto-oncogene c-Rel-like K09254 REL; c-Rel proto-oncogene protein
C RHR (Rel homology region) Ankyrin only
D 104404537 NFKBIA; NF-kappa-B inhibitor alpha K04734 NFKBIA; NF-kappa-B inhibitor alpha
D 104411914 NFKBID; NF-kappa-B inhibitor delta K14214 NFKBID; NF-kappa-B inhibitor delta
D 104411601 NF-kappa-B inhibitor epsilon-like K05872 NFKBIE; NF-kappa-B inhibitor epsilon
D 104399952 NFKBIZ; NF-kappa-B inhibitor zeta isoform X1 K14242 NFKBIZ; NF-kappa-B inhibitor zeta
D 104403934 GABPB2; GA-binding protein subunit beta-2 K09454 GABPB; GA-binding protein transcription factor, beta
D 104406952 GABPB1; GA-binding protein subunit beta-1 isoform X1 K09454 GABPB; GA-binding protein transcription factor, beta
C RHR (Rel homology region) NF-AT
D 104411737 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
D 104405455 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
D 104400257 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
D 104413456 NFAT5; nuclear factor of activated T-cells 5 K17335 NFAT5; nuclear factor of activated T-cells 5
C STAT
D 104413420 STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 K11220 STAT1; signal transducer and activator of transcription 1
D 104399491 STAT4; signal transducer and activator of transcription 4 K11222 STAT4; signal transducer and activator of transcription 4
C p53
D 104410865 LOW QUALITY PROTEIN: tumor protein 63-like K10149 TP63; tumor protein p63
C MADS-box regulators of differentiation, MEF-2
D 104409545 MEF2A; myocyte-specific enhancer factor 2A K09260 MEF2A; MADS-box transcription enhancer factor 2A
D 104409139 MEF2C; myocyte-specific enhancer factor 2C K04454 MEF2C; MADS-box transcription enhancer factor 2C
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
D 104405310 SRF; serum response factor K04378 SRF; serum response factor
C SAND domain-containing proteins
D 104407442 AIRE; autoimmune regulator K10603 AIRE; autoimmune regulator
D 104412239 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
D 104403556 GMEB1; glucocorticoid modulatory element-binding protein 1 K24505 GMEB; glucocorticoid modulatory element-binding protein
D 104404604 GMEB2; LOW QUALITY PROTEIN: glucocorticoid modulatory element-binding protein 2 K24505 GMEB; glucocorticoid modulatory element-binding protein
C TATA-binding proteins
D 104405733 TBP; TATA-box-binding protein isoform X1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 104406967 TATA-box-binding protein-like K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 104400728 TBPL1; TATA box-binding protein-like protein 1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C HMG SOX
D 104404312 SOX14; transcription factor SOX-14 K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 104403888 SOX2; transcription factor SOX-2 K16796 SOX2; transcription factor SOX2 (SOX group B)
D 104404170 SOX5; transcription factor SOX-5 K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D)
D 104408613 SOX13; transcription factor SOX-13 K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D)
D 104405311 SOX18; LOW QUALITY PROTEIN: transcription factor SOX-18 K09270 SOX7S; transcription factor SOX7/8/10/18 (SOX group E/F)
D 104406717 SOX10; transcription factor SOX-10 K09270 SOX7S; transcription factor SOX7/8/10/18 (SOX group E/F)
D 104409543 SOX30; transcription factor SOX-30 K09271 SOX15_30; transcription factor SOX15/30
D 104406346 BBX; LOW QUALITY PROTEIN: HMG box transcription factor BBX K21643 BBX; HMG box transcription factor BBX
D 104409211 HBP1; HMG box-containing protein 1 K21644 HBP1; HMG box transcription factor 1
C HMG TCF-1
D 104411041 LEF1; lymphoid enhancer-binding factor 1 K04492 LEF1; lymphoid enhancer-binding factor 1
D 104408659 lymphoid enhancer-binding factor 1-like K02620 TCF7; transcription factor 7
D 104411918 TCF7L2; transcription factor 7-like 2 K04491 TCF7L2; transcription factor 7-like 2
C HMG2-related
C UBF
D 104408323 UBTF; nucleolar transcription factor 1 K09273 UBTF; upstream-binding transcription factor
C Other HMG box factors
C Heteromeric CCAAT factors
D 104400452 NFYA; nuclear transcription factor Y subunit alpha isoform X1 K08064 NFYA; nuclear transcription factor Y, alpha
D 104407047 NFYB; nuclear transcription factor Y subunit beta K08065 NFYB; nuclear transcription Y subunit beta
D 104407978 NFYC; nuclear transcription factor Y subunit gamma isoform X1 K08066 NFYC; nuclear transcription factor Y, gamma
C Grainyhead
D 104399275 transcription factor CP2 K09275 TFCP2; transcription factor CP2 and related proteins
D 104412760 GRHL3; grainyhead-like protein 3 homolog K09275 TFCP2; transcription factor CP2 and related proteins
D 104399328 GRHL1; grainyhead-like protein 1 homolog K09275 TFCP2; transcription factor CP2 and related proteins
D 104404960 UBP1; upstream-binding protein 1 K09275 TFCP2; transcription factor CP2 and related proteins
D 104399693 transcription factor CP2-like protein 1 K09275 TFCP2; transcription factor CP2 and related proteins
D 104402388 GRHL2; grainyhead-like protein 2 homolog K09275 TFCP2; transcription factor CP2 and related proteins
C Cold-shock domain factors, DbpA-like
D 104401209 LOW QUALITY PROTEIN: Y-box-binding protein 3-like K06099 CSDA; cold shock domain protein A
C Cold-shock domain factors, YB-1/DbpB-like
D 104413561 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
C Cold-shock domain factors, FRG Y2-like
C Runt
D 104404098 RUNX2; runt-related transcription factor 2 K09278 RUNX2; runt-related transcription factor 2
C MYRF
D 104406193 MYRF; myelin regulatory factor K24768 MYRF; myelin regulatory factor [EC:3.4.-.-]
B Other transcription factors
C HMGI(Y)
C NUPR
E Line #4
C Pocket domain Rb
D 104402086 RB1; retinoblastoma-associated protein K06618 RB1; retinoblastoma-associated protein
D 104407726 RBL1; retinoblastoma-like protein 1 K04681 RBL1; retinoblastoma-like protein 1
D 104401950 RBL2; retinoblastoma-like protein 2 K16332 RBL2; retinoblastoma-like protein 2
C Pocket domain CBP
D 104401705 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
D 104406465 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C T-box
D 104406834 T; brachyury protein K10172 BRA; brachyury protein
D 104410502 EOMES; eomesodermin homolog K10173 EOMES; eomesodermin protein
D 104413607 TBX4; T-box transcription factor TBX4 K10178 TBX4; T-box protein 4
D 104412935 TBX5; T-box transcription factor TBX5 K10179 TBX5; T-box protein 5
D 104404443 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
D 104403334 TBX18; T-box transcription factor TBX18 K10183 TBX18; T-box protein 18
D 104410101 TBX19; T-box transcription factor TBX19 K10184 TBX19; T-box protein 19
D 104413277 LOW QUALITY PROTEIN: T-box transcription factor TBX20-like K10185 TBX20; T-box protein 20
C DMRT
D 104407940 DMRT1; doublesex- and mab-3-related transcription factor 1 K19488 DMRT1; doublesex- and mab-3-related transcription factor 1
D 104405863 DMRT2; doublesex- and mab-3-related transcription factor 2 K19489 DMRT2; doublesex- and mab-3-related transcription factor 2
D 104401039 DMRT3; doublesex- and mab-3-related transcription factor 3 K19490 DMRT3; doublesex- and mab-3-related transcription factor 3
D 104406336 doublesex- and mab-3-related transcription factor B1-like K19492 DMRT6; doublesex- and mab-3-related transcription factor 6
C LRRFIP
D 104405353 LRRFIP1; leucine-rich repeat flightless-interacting protein 1 K26434 LRRFIP; leucine-rich repeat flightless-interacting protein
D 104407195 LRRFIP2; leucine-rich repeat flightless-interacting protein 2 isoform X1 K26434 LRRFIP; leucine-rich repeat flightless-interacting protein
C TCP
C AP2/ERF
C WRKY
C LOB
C Copper-fist proteins fungal regulators
C Others
D 104411796 CARF; calcium-responsive transcription factor K21595 CARF; calcium-responsive transcription factor
D 104407904 GCM2; chorion-specific transcription factor GCMb K21598 GCM; chorion-specific transcription factor GCM
D 104413730 GCM1; chorion-specific transcription factor GCMa K21598 GCM; chorion-specific transcription factor GCM
D 104404099 TMEM18; transmembrane protein 18 K22145 TMEM18; transmembrane protein 18
D 104404595 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D 104404964 RBPJ; recombining binding protein suppressor of hairless K06053 RBPSUH; recombining binding protein suppressor of hairless
D 104411063 RBPJL; LOW QUALITY PROTEIN: recombining binding protein suppressor of hairless-like protein K06053 RBPSUH; recombining binding protein suppressor of hairless
D 104399353 GON4L; GON-4-like protein K23804 GON4L; GON-4-like protein
D 104399646 MYEF2; myelin expression factor 2 K24992 MYEF2; myelin expression factor 2
D 104408816 CDCA7; cell division cycle-associated protein 7 K23408 CDCA7; cell division cycle-associated protein 7
D 104409859 CDCA7L; cell division cycle-associated 7-like protein K23408 CDCA7; cell division cycle-associated protein 7
D 104402759 NKRF; NF-kappa-B-repressing factor K26458 NKRF; NF-kappa-B-repressing factor
#
AProkaryotic type
B Helix-turn-helix
C AraC family
C LysR family
C DeoR family
C LacI family
C GntR family
C TetR/AcrR family
C Lrp/AsnC family
C LuxR family
C MarR family
C MerR family
C Fur family
C IclR family
C CRP/FNR family
C Rrf2 family
C ArsR family
C XRE family
C PadR family
C Other families
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 7, 2024
#
Classification taken and modified from TRANSFAC 7.0