+D Messenger RNA Biogenesis KO #

  Prokaryotic Defense System - Nostoc sp. CENA543

% ! ACRISPR-Cas system B Universal Cas proteins C CLI64_08765 type I-D CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 C CLI64_29710 type I-MYXAN CRISPR-associated endonuclease Cas4/Cas1 K15342 cas1; CRISP-associated protein Cas1 C CLI64_08760 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2 C CLI64_29715 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2 B Type I CRISPR-Cas system C Type I signiture cas proteins D CLI64_08795 cas3; type I-D CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D CLI64_29690 CRISPR-associated helicase/endonuclease Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] C Subtype I-A factors D CLI64_22085 CRISPR-associated protein K19075 cst2; CRISPR-associated protein Cst2 D CLI64_29700 type I-B CRISPR-associated protein Cas7/Cst2/DevR K19075 cst2; CRISPR-associated protein Cst2 D CLI64_08770 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D CLI64_22080 cas5; type I-MYXAN CRISPR-associated protein Cas5/Cmx5/DevS K19090 cas5t; CRISPR-associated protein Cas5t D CLI64_29705 cas5; type I-MYXAN CRISPR-associated protein Cas5/Cmx5/DevS K19090 cas5t; CRISPR-associated protein Cas5t D CLI64_03375 cas6; CRISPR-associated endoribonuclease Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D CLI64_05035 CRISPR-associated protein Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D CLI64_08775 CRISPR-associated protein Cas5 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] C Subtype I-B factors D CLI64_08770 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] C Subtype I-C factors D CLI64_08770 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] C Subtype I-D factors D CLI64_08780 cas5d; type I-D CRISPR-associated protein Cas5/Csc1 K19120 csc1; CRISPR-associated protein Csc1 D CLI64_08785 cas7d; type I-D CRISPR-associated protein Cas7/Csc2 K19121 csc2; CRISPR-associated protein Csc2 D CLI64_08790 cas10d; type I-D CRISPR-associated protein Cas10d/Csc3 K19122 csc3; CRISPR-associated protein Csc3 D CLI64_08770 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D CLI64_03375 cas6; CRISPR-associated endoribonuclease Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D CLI64_05035 CRISPR-associated protein Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D CLI64_08775 CRISPR-associated protein Cas5 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] C Subtype I-E factors C Subtype I-F factors C Subtype I-U factors B Type II CRISPR-Cas system C Type II signiture cas proteins C Subtype II-A factors C Subtype II-B factors D CLI64_08770 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] B Type III CRISPR-Cas system C Type III signiture cas proteins D CLI64_05060 cas10; type III-A CRISPR-associated protein Cas10/Csm1 K07016 csm1; CRISPR-associated protein Csm1 C Subtype III-A factors D CLI64_05055 csm2; type III-A CRISPR-associated protein Csm2 K19138 csm2; CRISPR-associated protein Csm2 D CLI64_05050 csm3; type III-A CRISPR-associated RAMP protein Csm3 K09002 csm3; CRISPR-associated protein Csm3 D CLI64_05045 csm4; type III-A CRISPR-associated RAMP protein Csm4 K19139 csm4; CRISPR-associated protein Csm4 D CLI64_05040 csm5; type III-A CRISPR-associated RAMP protein Csm5 K19140 csm5; CRISPR-associated protein Csm5 C Subtype III-B factors C Subtype III-U factors D CLI64_05065 CRISPR-associated protein Csx3 K19144 csx3; CRISPR-associated protein Csx3 D CLI64_05070 CRISPR-associated protein Csx3 K19144 csx3; CRISPR-associated protein Csx3 # ARestriction and modification system (R-M system) B Type I R-M system C CLI64_05985 restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] C CLI64_15375 DEAD/DEAH box helicase K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] C CLI64_22075 restriction endonuclease subunit R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] C CLI64_05950 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] C CLI64_15355 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] C CLI64_22065 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] C CLI64_30235 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] C CLI64_05940 DNA methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] C CLI64_15360 SAM-dependent methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] C CLI64_22060 hypothetical protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] C CLI64_22070 restriction endonuclease subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] C CLI64_30210 SAM-dependent methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] B Type II R-M system C Restriction endonucleases C DNA methyltransferases D CLI64_18860 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D CLI64_25085 modification methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D CLI64_25850 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D CLI64_20750 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D CLI64_21050 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D CLI64_23440 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D CLI64_29955 hypothetical protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] B Type III R-M system B Type IV R-M system C CLI64_22650 HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] # AToxin-antitoxin system (TA system) B Type I TA system C Hok-Sok C SymE-SymR C Ldr-Rdl C TisB-IstR C Ibs-Sib C ShoB-OhsC C RalR-RalA B Type II TA system C MazF-MazE D CLI64_00380 PemK family transcriptional regulator K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D CLI64_20070 PemK family transcriptional regulator K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D CLI64_27600 hypothetical protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D CLI64_27615 hypothetical protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D CLI64_27620 CopG family transcriptional regulator K26989 mazE9; antitoxin MazE9 C ChpB-ChpS C YhaV-PrlF D CLI64_23815 endonuclease K19155 yhaV; toxin YhaV [EC:3.1.-.-] C RelE/StbE-RelB/StbD D CLI64_19665 cytotoxic translational repressor of toxin-antitoxin stability system K06218 relE; mRNA interferase RelE/StbE D CLI64_28610 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family K06218 relE; mRNA interferase RelE/StbE C YafQ-dinJ C YoeB-YefM D CLI64_28830 Txe/YoeB family addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-] D CLI64_28835 hypothetical protein K19159 yefM; antitoxin YefM C HipA-HipB C HicA-HicB D CLI64_20325 toxin-antitoxin system HicB family antitoxin K18843 hicB; antitoxin HicB C YafO-YafN C PspC-PspB C CcdB-CcdA C ParE-ParD D CLI64_23045 plasmid stabilization protein K19092 parE1_3_4; toxin ParE1/3/4 D CLI64_25925 plasmid stabilization protein K19092 parE1_3_4; toxin ParE1/3/4 D CLI64_01295 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4 D CLI64_01300 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4 D CLI64_09020 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4 D CLI64_23050 type II toxin-antitoxin system ParD family antitoxin K07746 parD1_3_4; antitoxin ParD1/3/4 C Doc-Phd C HigB-HigA D CLI64_20735 hypothetical protein K19166 higB; mRNA interferase HigB [EC:3.1.-.-] D CLI64_28385 hypothetical protein K19166 higB; mRNA interferase HigB [EC:3.1.-.-] D CLI64_16830 plasmid maintenance system killer protein K07334 higB-1; toxin HigB-1 D CLI64_20740 hypothetical protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA D CLI64_28390 transcriptional regulator K18831 higA; HTH-type transcriptional regulator / antitoxin HigA D CLI64_16835 higA; addiction module antidote protein, HigA family K21498 higA-1; antitoxin HigA-1 C MqsR-MqsA C VapC-VapB D CLI64_05955 prevent-host-death family protein K18829 mvpT; antitoxin VapB D CLI64_05660 hypothetical protein K28280 vapB22; antitoxin VapB22 C PezT-PezA C YobL-YobK C YokI-YokJ C YqcG-YqcF C YxiD-YxxD C FitB-FitA D CLI64_02515 VapC toxin family PIN domain ribonuclease K07062 fitB; toxin FitB [EC:3.1.-.-] D CLI64_05015 VapC toxin family PIN domain ribonuclease K07062 fitB; toxin FitB [EC:3.1.-.-] D CLI64_05020 plasmid stability protein K21495 fitA; antitoxin FitA C BC_0920-BC_0921 C SpoIISA-SpoIISB C Tse6-Tsi6 C Type II TA system related factors D CLI64_04380 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D CLI64_12880 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D CLI64_06015 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] B Type III TA system C AbiQ system B Type IV TA system C YeeV-YeeU C CptA-CptB C AbiEii-AbiEi B Type V TA system C GhoT-GhoS C Other GhoT/OrtT toxin family protein B Type VI TA system C SocB-SocA B Type VII TA system C Hha-TomB C TglT-TakA C HepT-MntA B Type VIII TA system C SdsR-RyeA # ADNA phosphothiolation system B Sulfur modification proteins C CLI64_00105 IscS subfamily cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C CLI64_00300 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C CLI64_02500 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C CLI64_03900 aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C CLI64_09085 dndC; DNA phosphorothioation system sulfurtransferase DndC K19170 dndC; DNA sulfur modification protein DndC C CLI64_09080 dndD; DNA sulfur modification protein DndD K19171 dndD; DNA sulfur modification protein DndD C CLI64_12110 ATP-binding protein K19171 dndD; DNA sulfur modification protein DndD C CLI64_15825 dndE; DNA sulfur modification protein DndE K19172 dndE; DNA sulfur modification protein DndE B DNA phosphorothioation-dependent restriction proteins ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 19, 2025