+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Natronomonas pharaonis</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    NP_3274A cas1; CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    NP_3276A cas2; CRISPR-associated endonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      NP_3270A cas3; CRISPR-associated helicase Cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
D      NP_3260A csm6; CRISPR-associated DNA-binding protein Csm6	K07725 csa3; CRISPR-associated protein Csa3 
D      NP_3272A cas4; CRISPR-associated exonuclease Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      NP_3262A cas6; CRISPR-associated endoribonuclease Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-B factors
D      NP_3272A cas4; CRISPR-associated exonuclease Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-C factors
D      NP_3272A cas4; CRISPR-associated exonuclease Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-D factors
D      NP_3268A csc1; CRISPR-associated protein Csc1	K19120 csc1; CRISPR-associated protein Csc1 
D      NP_3266A cas7; CRISPR-associated protein Cas7	K19121 csc2; CRISPR-associated protein Csc2 
D      NP_3264A cas10d; CRISPR-associated protein Cas10d	K19122 csc3; CRISPR-associated protein Csc3 
D      NP_3272A cas4; CRISPR-associated exonuclease Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      NP_3262A cas6; CRISPR-associated endoribonuclease Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
D      NP_3272A cas4; CRISPR-associated exonuclease Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      NP_0260A zim; CTAG modification methylase	K24451 zim; modification methylase 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      NP_6090A PemK family protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      NP_6130A RelE family protein	K06218 relE; mRNA interferase RelE/StbE 
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      NP_4666A homolog to endonuclease VapC	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      NP_0810A ftsZ1; cell division protein FtsZ, type I	K03531 ftsZ; cell division protein FtsZ 
D      NP_5324A ftsZ2; cell division protein FtsZ, type II	K03531 ftsZ; cell division protein FtsZ 
D      NP_5294A ftsZ5; FtsZ family protein, noncanonical	K03531 ftsZ; cell division protein FtsZ 
D      NP_3694A gltS; glutamate--tRNA(Glu/Gln) ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
D      NP_4986A nob1; rRNA maturation endonuclease Nob1	K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023