+E Ubiquitin system KO
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Ubiquitin System - Nematostella vectensis (starlet sea anemone)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 5503429 polyubiquitin-B K04551 UBB; ubiquitin B
C 5517685 ubiquitin K04551 UBB; ubiquitin B
C 5503649 polyubiquitin-C isoform X1 K08770 UBC; ubiquitin C
C 5502145 ubiquitin K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 116608805 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 116608806 ubiquitin-60S ribosomal protein L40-like K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 5499773 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 5520747 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 5504460 ubiquitin-like protein FUBI K02983 RP-S30e; small subunit ribosomal protein S30e
C 5517976 small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 5517999 gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
C 5514207 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 5520146 ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
C 5505188 ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
C 5519172 ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 5509989 AN1-type zinc finger protein 4 K12163 ZFAND4; AN1-type zinc finger protein 4
#
AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 5504534 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 5521767 SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 5518499 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 5513412 NEDD8-activating enzyme E1 catalytic subunit K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 5516526 NEDD8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 5520875 adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 5508784 ubiquitin-like modifier-activating enzyme 5 isoform X1 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 5510370 ubiquitin-like modifier-activating enzyme 6 isoform X1 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 5522103 ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 116614310 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 5508032 ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 5515607 ubiquitin-conjugating enzyme E2-17 kDa isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 5505215 ubiquitin-conjugating enzyme E2 E1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 5505228 ubiquitin-conjugating enzyme E2 E3 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 5511552 ubiquitin-conjugating enzyme E2 G1 isoform X2 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 5521299 ubiquitin-conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 5521000 ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 5510451 ubiquitin-conjugating enzyme E2 J1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 5510076 ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 5511170 ubiquitin-conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 5504819 ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 5502219 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 5512277 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 5520149 (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 5508061 ubiquitin-conjugating enzyme E2Q-like protein 1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 5505725 ubiquitin-conjugating enzyme E2 Q2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 5502061 ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 5509668 ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 5520025 ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 5498829 ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 5517164 ubiquitin-conjugating enzyme E2 U K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 5503004 ubiquitin-conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 5521870 ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 5518917 baculoviral IAP repeat-containing protein 6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 5519859 SUMO-conjugating enzyme UBC9-B isoform X1 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 5520669 SUMO-conjugating enzyme UBC9-A K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 5516788 NEDD8-conjugating enzyme UBE2F isoform X2 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 5506729 NEDD8-conjugating enzyme Ubc12 isoform X1 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 5504068 NEDD8-conjugating enzyme ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 5504069 NEDD8-conjugating enzyme ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 5499405 NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 5517291 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 5510669 ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 5506607 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
C 5499388 ubiquitin-fold modifier-conjugating enzyme 1-like K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 5512130 ubiquitin-protein ligase E3A isoform X1 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 5519573 ubiquitin-protein ligase E3B isoform X1 K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 116603739 ubiquitin-protein ligase E3C-like K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 5510277 E3 ubiquitin-protein ligase E3D isoform X3 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 5521489 NEDD4-like E3 ubiquitin-protein ligase WWP1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 5506437 E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 5518172 E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 116620378 E3 ubiquitin-protein ligase HUWE1-like isoform X1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 5501000 apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 5497161 apoptosis-resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 5508594 uncharacterized protein LOC5508594 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 116613544 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR5-like K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 5500713 LOW QUALITY PROTEIN: G2/M phase-specific E3 ubiquitin-protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 5509406 uncharacterized protein LOC5509406 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 5510733 uncharacterized protein LOC5510733 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 116614552 uncharacterized protein LOC116614552 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 5517638 probable E3 ubiquitin-protein ligase HERC1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 5508703 E3 ubiquitin-protein ligase HERC2 isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 5505947 probable E3 ubiquitin-protein ligase HERC4 isoform X1 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 5506160 uncharacterized protein LOC5506160 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 5521769 E3 ubiquitin-protein ligase HECW2 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 5512974 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HECTD1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 5505403 probable E3 ubiquitin-protein ligase HECTD2 isoform X4 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 5514428 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HECTD3 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 5507564 uncharacterized protein LOC5507564 isoform X2 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 5516610 probable E3 ubiquitin-protein ligase HECTD4 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 5502827 NEDD4 family-interacting protein 1-like K25839 NDFIP; NEDD4 family-interacting protein
B U-box type E3
C 5516787 ubiquitin conjugation factor E4 A isoform X1 K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 5513247 ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 5509603 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 116616562 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CHIP-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 5501112 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 5501116 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 5519569 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 5506912 E3 ubiquitin-protein ligase RBBP6 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 5519902 RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 5503417 E3 ubiquitin-protein ligase BRE1B K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 116608807 E3 ubiquitin-protein ligase CBL-B-B-like K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 5516955 E3 ubiquitin-protein ligase SIAH1A K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D 5520393 E3 ubiquitin-protein ligase PDZRN3-B isoform X1 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 5509421 E3 ubiquitin-protein ligase MARCH8 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 5508720 E3 ubiquitin-protein ligase MARCH4 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 5508777 E3 ubiquitin-protein ligase MARCH1 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 5521055 E3 ubiquitin-protein ligase MARCH5 isoform X1 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 5519426 E3 ubiquitin-protein ligase MARCH6 isoform X1 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 5508364 protein Mdm4 isoform X1 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 5517942 transcriptional repressor NF-X1 K12236 NFX1; transcriptional repressor NF-X1
D 5513602 NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 5504959 E3 ubiquitin-protein ligase pellino homolog 2 K11964 PELI; pellino [EC:2.3.2.27]
D 5499906 E3 ubiquitin-protein ligase pellino homolog 3 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 5512775 peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 5515731 peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 5504347 peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 5512842 E3 ubiquitin-protein ligase parkin isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 116605038 ankyrin repeat and IBR domain-containing protein 1-like K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 5521236 ankyrin repeat and IBR domain-containing protein 1 isoform X1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 5508079 E3 ubiquitin-protein ligase arih1 isoform X1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 5520326 E3 ubiquitin-protein ligase ARIH2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 5510882 ranBP-type and C3HC4-type zinc finger-containing protein 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 5519185 E3 ubiquitin-protein ligase RNF14 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 5512303 E3 ubiquitin-protein ligase RNF14 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 116607601 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF19A-like K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 5518586 E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 5516539 E3 ubiquitin-protein ligase RNF34 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 5508948 probable E3 ubiquitin-protein ligase RNF144A-A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 5512697 E3 ubiquitin-protein ligase rnf168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 5514953 E3 ubiquitin-protein ligase RNF216 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
D 5520915 TNF receptor-associated factor 6 isoform X1 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 5508573 E3 ubiquitin-protein ligase TRAF7 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
D 5520220 E3 ubiquitin-protein ligase TRAF7 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 5511942 E3 ubiquitin-protein ligase TRIM9 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 5513046 tripartite motif-containing protein 67 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 5515873 E3 ubiquitin-protein ligase TRIM23 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 5499285 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM23 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 5519868 E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 5513407 tripartite motif-containing protein 45 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 5516148 E3 ubiquitin-protein ligase TRIM37 isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 5500983 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5514563 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5517547 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 116607911 tripartite motif-containing protein 45-like K12021 TRIM45; tripartite motif-containing protein 45
D 116614898 tripartite motif-containing protein 45-like K12021 TRIM45; tripartite motif-containing protein 45
D 116618345 tripartite motif-containing protein 45-like K12021 TRIM45; tripartite motif-containing protein 45
D 5504282 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5505245 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5513025 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5498228 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5498952 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5505632 tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 5501811 tripartite motif-containing protein 45 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 5503660 tripartite motif-containing protein 45 isoform X5 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 5504154 tripartite motif-containing protein 45 isoform X1 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 5504157 E3 ubiquitin-protein ligase TRIM56 isoform X3 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 5504165 tripartite motif-containing protein 45 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 5500515 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5500586 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5507863 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5507864 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5515793 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5503869 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5508348 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5516408 tripartite motif-containing protein 2 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5518775 RING finger protein nhl-1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5519339 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5519486 RING finger protein nhl-1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5519821 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5519837 E3 ubiquitin-protein ligase TRIM71 isoform X1 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5519919 tripartite motif-containing protein 2 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5509508 uncharacterized protein LOC5509508 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5521001 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 116611883 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5521557 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5505233 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5513087 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5513408 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 5505647 E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 5502492 E3 ubiquitin-protein ligase UBR2 isoform X1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 5514850 E3 ubiquitin-protein ligase ubr3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 5515332 E3 ubiquitin-protein ligase UBR4 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 5509699 putative E3 ubiquitin-protein ligase UBR7 isoform X1 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 5505888 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 116617912 bifunctional apoptosis regulator-like K15684 BFAR; bifunctional apoptosis regulator
D 5501165 uncharacterized protein LOC5501165 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 5502471 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 5521771 uncharacterized protein LOC5521771 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 116620371 E3 ubiquitin-protein ligase Hakai-like isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 5504501 E3 ubiquitin-protein ligase CCNB1IP1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 5513713 E3 ubiquitin-protein ligase CHFR isoform X1 K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 5513248 flocculation protein FLO11 isoform X3 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 116610622 DC-STAMP domain-containing protein 2-like K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 5507270 E3 ubiquitin-protein ligase DTX4 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 5509739 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 5508624 E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 5515355 E3 ubiquitin-protein ligase LRSAM1 isoform X1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 5518804 E3 ubiquitin-protein ligase listerin isoform X1 K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 5507587 mitogen-activated protein kinase kinase kinase 1 isoform X1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 5503436 RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 5516546 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 5508983 E3 ubiquitin-protein ligase MIB2 isoform X2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 5501740 probable E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 5511055 mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 116619411 E3 ubiquitin-protein ligase MYLIP-like K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 116619975 E3 ubiquitin-protein ligase MYLIP-like K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 5513369 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 5513410 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 5519263 ORC ubiquitin ligase 1 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 5511158 E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 5501353 RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 5502167 RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 5516083 E3 ubiquitin-protein ligase MIEL1 isoform X1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 5505910 roquin-2 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 116612185 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase COP1-like K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 5520055 E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 5522148 E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 116614112 uncharacterized protein LOC116614112 isoform X1 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 5508864 E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 5520841 E3 ubiquitin-protein ligase rnf8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 5519565 RING finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 5512333 RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 5507822 E3 ubiquitin-protein ligase RNF13 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 5507294 E3 ubiquitin-protein ligase ZNF598 isoform X1 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 5520365 E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 5516260 uncharacterized protein LOC5516260 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 5501989 uncharacterized protein LOC5501989 isoform X2 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 5521430 RING finger protein 44 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 5521804 E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 5521365 E3 ubiquitin-protein ligase RNF103 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 5503038 E3 ubiquitin-protein ligase RNF115 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 5512185 RING finger protein 121 isoform X2 K15698 RNF121_175; RING finger protein 121/175
D 5514394 uncharacterized protein LOC5514394 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 5521383 RING finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 5502223 E3 ubiquitin-protein ligase RNF146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 5509598 E3 ubiquitin ligase RNF157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 5505823 E3 ubiquitin-protein ligase RNF170 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 5510593 uncharacterized protein LOC5510593 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 5517574 E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 5499733 E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 5519403 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase rnf213-alpha K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 5519404 E3 ubiquitin-protein ligase rnf213-alpha K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 5509270 uncharacterized protein LOC5509270 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 5517443 E3 ubiquitin-protein ligase RNF220 isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 5508912 U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 5517544 E3 ubiquitin-protein ligase SHPRH isoform X1 K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 5516385 E3 ubiquitin-protein ligase SH3RF1 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 116609537 helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 5520743 E3 ubiquitin-protein ligase synoviolin A K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 5521397 E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 5516287 E3 ubiquitin-protein ligase Topors isoform X1 K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 5503294 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 116611089 E3 ubiquitin-protein ligase TRAIP-like K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 5512595 E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 116616870 E3 ubiquitin-protein ligase TTC3-like isoform X1 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 5502190 E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 5512127 E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 5511765 E3 ubiquitin-protein ligase ZNF598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 5512253 E3 ubiquitin-protein ligase znrf2 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 5502937 E3 ubiquitin-protein ligase ZNRF3 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 5515518 E3 ubiquitin-protein ligase ZSWIM2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
D 5519747 E3 ubiquitin-protein ligase RGLG4 K16280 RGLG; E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27]
D 116620704 ankyrin repeat and SOCS box protein 13-like K19044 XBAT32_33; E3 ubiquitin-protein ligase XBAT32/33 [EC:2.3.2.27]
B Atypical E3
C 5519618 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 5514965 probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 5516287 E3 ubiquitin-protein ligase Topors isoform X1 K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 5503294 E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 116616346 LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2-like K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 5503141 E3 SUMO-protein ligase PIAS2 isoform X1 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 5518625 E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 5518262 RING finger protein 212B K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 116603571 zinc finger BED domain-containing protein 1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 5513886 E3 UFM1-protein ligase 1 homolog isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 116601872 DCN1-like protein 1 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 116606486 DCN1-like protein 4 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 116615533 DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 5509071 cullin-1 K03347 CUL1; cullin 1
D Adaptor protein
E 5514721 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 5521070 F-box/WD repeat-containing protein 1A isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 5505929 F-box/WD repeat-containing protein 2 K10261 FBXW2; F-box and WD-40 domain protein 2
E 5503358 F-box/WD repeat-containing protein 4 isoform X1 K10262 FBXW4; F-box and WD-40 domain protein 4
E 5519346 F-box/WD repeat-containing protein 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E 5503203 F-box/WD repeat-containing protein pof1 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 5516005 probable E3 ubiquitin ligase complex SCF subunit sconB isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 116606978 F-box/WD repeat-containing protein 7-like isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 5510683 uncharacterized protein LOC5510683 K10260 FBXW7; F-box and WD-40 domain protein 7
E 5504209 F-box/WD repeat-containing protein 11 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 5514116 F-box/WD repeat-containing protein 7 K10260 FBXW7; F-box and WD-40 domain protein 7
E 5511319 F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 5519086 F-box/WD repeat-containing protein 9 K10265 FBXW9; F-box and WD-40 domain protein 9
E 5500553 F-box/WD repeat-containing protein 10 K10266 FBXW10; F-box and WD-40 domain protein 10
E 5506099 CMT1A duplicated region transcript 1 protein K10266 FBXW10; F-box and WD-40 domain protein 10
E 5518839 F-box/WD repeat-containing protein 7 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 5517154 S-phase kinase-associated protein 2 isoform X1 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 5515527 F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5503780 F-box/LRR-repeat protein 2 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5517947 F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5519582 F-box/LRR-repeat protein 7 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5510323 F-box/LRR-repeat protein 15 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5510417 F-box/LRR-repeat protein 20 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5510426 F-box/LRR-repeat protein 7 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5521918 F-box/LRR-repeat protein 7 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 116615709 F-box/LRR-repeat protein 20-like K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 116616890 F-box/LRR-repeat protein 2-like isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 116618146 F-box/LRR-repeat protein 2-like K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5525209 F-box/LRR-repeat protein 5 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5512629 F-box/LRR-repeat protein fbxl-1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5496779 dynein regulatory complex subunit 6 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5497053 F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5513012 F-box/LRR-repeat protein 7 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5513124 LOW QUALITY PROTEIN: dynein regulatory complex subunit 6 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5506113 F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 5517965 F-box/LRR-repeat protein 4 isoform X1 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 5518247 F-box/LRR-repeat protein 5 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 5519296 F-box/LRR-repeat protein 6 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 5508859 F-box/LRR-repeat protein 2 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 116601213 F-box/LRR-repeat protein fbxl-1-like K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 5520820 F-box/LRR-repeat protein 2 isoform X1 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 116611676 F-box/LRR-repeat protein 7-like K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 5498911 F-box/LRR-repeat protein 2 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 5508704 F-box/LRR-repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 5512738 F-box/LRR-repeat protein 2 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 5512876 lysine-specific demethylase 2B isoform X4 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 5514413 F-box/LRR-repeat protein 7 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 5520399 dynein regulatory complex subunit 6 K10279 FBXL13; dynein regulatory complex subunit 6
E 5502965 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 5510224 F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 5505272 F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 5518696 F-box/LRR-repeat protein 17 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 5500977 uncharacterized protein LOC5500977 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 5507066 uncharacterized protein LOC5507066 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 5506097 cyclin-F K10289 CCNF; F-box protein 1 (cyclin F)
E 5515395 F-box only protein 3 K10290 FBXO3; F-box protein 3
E 5509813 F-box only protein 4 isoform X2 K10291 FBXO4; F-box protein 4
E 5505769 F-box only protein 5 isoform X1 K10292 FBXO5; F-box protein 5
E 5507664 F-box only protein 7 isoform X2 K10293 FBXO7; F-box protein 7
E 5519236 F-box only protein 8 K10294 FBXO8; F-box protein 8
E 116605649 F-box only protein 8-like K10294 FBXO8; F-box protein 8
E 5511536 F-box only protein 9 isoform X1 K10295 FBXO9; F-box protein 9
E 5500628 F-box only protein 10 K10296 FBXO10; F-box protein 10
E 5508768 F-box only protein 11 K10297 FBXO11; F-box protein 11
E 5507376 F-box only protein 15 isoform X1 K10298 FBXO15; F-box protein 15
E 116618803 F-box only protein 15-like K10298 FBXO15; F-box protein 15
E 5508106 F-box only protein 16 K10299 FBXO16; F-box protein 16
E 5500709 F-box DNA helicase 1 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 5516593 F-box only protein 21 K10301 FBXO21; F-box protein 21
E 5510951 F-box only protein 22 K10302 FBXO22; F-box protein 22
E 5511288 F-box only protein 30 K10307 FBXO30; F-box protein 30
E 5518037 F-box only protein 31 K10308 FBXO31; F-box protein 31
E 116620855 F-box only protein 36-like K10312 FBXO36; F-box protein 36
E 5504899 F-box only protein 36 K10312 FBXO36; F-box protein 36
E 5514647 F-box only protein 41 K10316 FBXO41; F-box protein 41
E 5514550 F-box only protein 42 K10317 FBXO42; F-box protein 42
E 5506730 F-box only protein 47 K10321 FBXO47; F-box protein 47
E 5499406 F-box only protein 47 K10321 FBXO47; F-box protein 47
C Cul2 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 5521344 cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 116614223 elongin-C K03872 ELOC; elongin-C
E 5508863 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 116621125 von Hippel-Lindau tumor suppressor homolog K03871 VHL; von Hippel-Lindau disease tumor supressor
E 5511981 leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 5500955 protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 5517590 protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 5507553 amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 5521546 kelch domain-containing protein 2 K25807 KLHDC2; kelch domain-containing protein 2
E 5514814 kelch domain-containing protein 3 K25808 KLHDC3; kelch domain-containing protein 3
E 5502101 kelch domain-containing protein 10 K25809 KLHDC10; kelch domain-containing protein 10
E 5517487 protein zyg-11 homolog B K10350 ZYG11; Zyg-11 protein
E 5509759 protein zer-1 homolog isoform X2 K10350 ZYG11; Zyg-11 protein
E 116618413 zinc finger SWIM domain-containing protein 8-like K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 5506629 cullin-3 K03869 CUL3; cullin 3
E 5507929 cullin-3-B isoform X2 K03869 CUL3; cullin 3
E 5498125 cullin-3-B K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 5521371 kelch-like protein 2 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 5522018 kelch-like protein 5 isoform X2 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 5514896 kelch-like protein 3 K10443 KLHL2_3; kelch-like protein 2/3
E 5501652 kelch-like protein 18 K10443 KLHL2_3; kelch-like protein 2/3
E 5516064 kelch-like protein 3 K10443 KLHL2_3; kelch-like protein 2/3
E 5518725 kelch-like protein 2 K10443 KLHL2_3; kelch-like protein 2/3
E 5510784 kelch-like protein 2 K10443 KLHL2_3; kelch-like protein 2/3
E 5521925 kelch-like protein 8 K10446 KLHL8; kelch-like protein 8
E 5501085 kelch-like protein 12 isoform X1 K10450 KLHL12; kelch-like protein 12
E 5510024 kelch-like protein 20 K10450 KLHL12; kelch-like protein 12
E 5505042 kelch-like protein 12 K10450 KLHL12; kelch-like protein 12
E 5505858 kelch-like protein 28 K10450 KLHL12; kelch-like protein 12
E 5514214 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 5517426 kelch-like protein 28 K10455 KLHL18; kelch-like protein 18
E 5521761 kelch-like protein 18 K10455 KLHL18; kelch-like protein 18
E 5513415 kelch-like protein 12 K10455 KLHL18; kelch-like protein 18
E 5506328 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5514600 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 5502198 kelch-like protein diablo isoform X2 K10457 KLHL20; kelch-like protein 20
E 5515608 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5517614 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5519334 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 5509298 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5520345 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5509637 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5521506 kelch domain-containing protein 8B K10457 KLHL20; kelch-like protein 20
E 5496065 kelch repeat and BTB domain-containing protein 12 K10457 KLHL20; kelch-like protein 20
E 5504645 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5505028 kelch-like protein 17 isoform X1 K10457 KLHL20; kelch-like protein 20
E 5505161 ring canal kelch homolog K10457 KLHL20; kelch-like protein 20
E 5500003 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 5513883 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 5506252 actin-binding protein IPP K13956 IPP; actin-binding protein IPP
E 5518989 kelch-like protein 28 K10464 KLHL28; kelch-like protein 28
E 5516001 BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 5517672 BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 5510116 BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 5521217 BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 5511013 BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 5515893 BTB/POZ domain-containing protein 6-B K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 5516801 BTB/POZ domain-containing protein 6-A K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 5518001 BTB/POZ domain-containing protein 3 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 116605835 BTB/POZ domain-containing protein 6-like K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 5521038 BTB/POZ domain-containing protein 3 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 5498208 BTB/POZ domain-containing protein 3 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 5508493 BTB/POZ domain-containing protein 7 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 5496856 uncharacterized protein LOC5496856 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 5510772 BTB/POZ domain-containing protein 9 isoform X1 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 5511399 BTB/POZ domain-containing protein 10 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 5519269 uncharacterized protein LOC5519269 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 5514559 germ cell-less protein-like 1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 5514601 BTB/POZ domain-containing protein 16 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 5517481 ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 5505594 ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform X1 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 5508001 rho-related protein racA isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 5508604 rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 5514052 rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 5509295 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 5522246 uncharacterized protein LOC5522246 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 116619985 uncharacterized protein LOC116619985 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 5511708 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 5520816 BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 5505940 BTB/POZ domain-containing protein kctd15-like K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 116608235 BTB/POZ domain-containing protein KCTD14-like K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 5510414 BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 116617152 BTB/POZ domain-containing protein KCTD16-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 5506069 BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 116604484 FH protein interacting protein FIP2-like K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 5499481 BTB/POZ domain-containing protein KCTD1 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 5521716 speckle-type POZ protein K10523 SPOP; speckle-type POZ protein
E 5516080 leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
E 5499673 leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 5507096 cullin-4A K10609 CUL4; cullin 4
E 5518106 cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 5514579 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 5507825 DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8
E 5508726 DET1 homolog K10571 DET1; de-etiolated-1
E 116612185 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase COP1-like K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 5500961 DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 5512210 protein cereblon isoform X1 K11793 CRBN; cereblon
E 5499088 protein cereblon isoform X1 K11793 CRBN; cereblon
E 116602121 short transient receptor potential channel 4-associated protein-like isoform X1 K11796 TRPC4AP; Trpc4-associated protein
E 5517150 DDB1- and CUL4-associated factor 1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 5515998 denticleless protein homolog K11790 DTL; denticleless
E 5516018 DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 5511960 DDB1- and CUL4-associated factor 5 isoform X1 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 5502652 DDB1- and CUL4-associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 5502867 DDB1- and CUL4-associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 5517004 DDB1- and CUL4-associated factor 7 isoform X1 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 5511685 DDB1- and CUL4-associated factor 8 isoform X2 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 5500611 WD and tetratricopeptide repeats protein 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 5522309 DDB1- and CUL4-associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 5518599 DDB1- and CUL4-associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 5511184 DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 5514746 DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 5517108 DDB1- and CUL4-associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 5520970 DDB1- and CUL4-associated factor 17 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 5510446 PH-interacting protein K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 5520692 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
E 5520058 WD repeat-containing protein 70 isoform X1 K24752 WDR70; WD repeat-containing protein 70
E 5521708 WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 5518202 RING-box protein 2 K10611 RBX2; RING-box protein 2
D Cullin
E 5510354 cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 116614223 elongin-C K03872 ELOC; elongin-C
E 5508863 elongin-B K03873 ELOB; elongin-B
D Target recognizing subunit
E 5516884 suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 5525264 suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 5499825 suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 5508565 uncharacterized protein LOC5508565 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 116615490 ankyrin repeat and SOCS box protein 3-like K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 5519423 ankyrin repeat and SOCS box protein 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 116616295 ankyrin repeat and SOCS box protein 13-like K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 5511986 uncharacterized protein LOC5511986 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 5513260 protein gustavus isoform X2 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 5520680 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 5520681 SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 5500689 RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 5505890 RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 5514721 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 5511319 F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 5509443 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E 5504223 anaphase-promoting complex subunit 2 isoform X1 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 5502298 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 5504943 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 5517109 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 5511855 anaphase-promoting complex subunit 1 isoform X1 K03348 APC1; anaphase-promoting complex subunit 1
E 5511886 anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 5515805 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 5503973 anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 5505700 anaphase-promoting complex subunit 5 isoform X1 K03352 APC5; anaphase-promoting complex subunit 5
E 5517352 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 5512872 anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 5515092 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 5510137 anaphase-promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E 116613085 anaphase-promoting complex subunit 13-like K12456 APC13; anaphase-promoting complex subunit 13
E 5506828 anaphase-promoting complex subunit 15B K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 5521771 uncharacterized protein LOC5521771 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 5506070 breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
D 5506613 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 116603519 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 5521126 BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 5504437 BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE
D 116604034 DNA repair protein RAD51 homolog B-like K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 5514394 uncharacterized protein LOC5514394 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 5506125 ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 5510882 ranBP-type and C3HC4-type zinc finger-containing protein 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 5518586 E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 5514983 E3 ubiquitin-protein ligase RMND5A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 5501978 ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 5517983 armadillo repeat-containing protein 8 K23336 ARMC8; armadillo repeat-containing protein 8
D 5502804 muskelin K23337 MKLN1; muskelin
D 5514407 muskelin isoform X1 K23337 MKLN1; muskelin
D 5502649 E3 ubiquitin-protein transferase MAEA K18624 MAEA; macrophage erythroblast attacher
D 5509658 glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 5502962 glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 5516193 protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 5520692 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 5505888 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 5515519 transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 5501334 erlin-2-B K23341 ERLIN; erlin
D 5506991 erlin-1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 5521260 limb region 1 protein homolog K25215 LMBR1L; protein LMBR1L
D 5505888 E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 5515389 ubiquitin-associated domain-containing protein 2 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 116605157 cullin-associated NEDD8-dissociated protein 1-like K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 5505010 cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 116620145 COMM domain-containing protein 1-like K22557 COMMD1; COMM domain containing 1
D 5499549 COMM domain-containing protein 1 K22557 COMMD1; COMM domain containing 1
D 116601176 COMM domain-containing protein 2-like K22558 COMMD2; COMM domain containing 2
D 5521191 COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 5521609 COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 5512500 COMM domain-containing protein 5 isoform X2 K22561 COMMD5; COMM domain containing 5
D 5512187 COMM domain-containing protein 6 K22562 COMMD6; COMM domain containing 6
D 5508923 COMM domain-containing protein 7 K22563 COMMD7; COMM domain containing 7
D 5516481 COMM domain-containing protein 8 K22564 COMMD8; COMM domain containing 8
D 5496582 COMM domain-containing protein 8 K22564 COMMD8; COMM domain containing 8
D 5507343 COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 5503835 COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 5519222 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 5514992 DDRGK domain-containing protein 1 isoform X2 K23344 DDRGK1; DDRGK domain-containing protein 1
D 116601133 glomulin-like K23345 GLMN; glomulin
D 5509394 kelch-like protein diablo K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 5503854 UBX domain-containing protein 7 isoform X1 K24350 UBXN7; UBX domain-containing protein 7
D 5516673 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 5516658 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 5502043 ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 5511294 SH3 domain-containing protein Dlish K26546 Dlish; SH3 domain-containing protein Dlish
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 5503931 ubiquitin carboxyl-terminal hydrolase calypso isoform X1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 5512201 ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 5509376 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D 5506037 ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 5519468 ubiquitin carboxyl-terminal hydrolase CYLD K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 116613971 ubiquitin carboxyl-terminal hydrolase 1-like isoform X1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 5506219 ubiquitin carboxyl-terminal hydrolase 2 isoform X2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 5508978 ubiquitin carboxyl-terminal hydrolase 3 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 5522191 ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 5511546 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 32 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 5506093 ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 5507749 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 5506431 probable ubiquitin carboxyl-terminal hydrolase FAF-X K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 5516298 ubiquitin carboxyl-terminal hydrolase 24 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 5512242 ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 5516407 ubiquitin carboxyl-terminal hydrolase 46 isoform X1 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 5508860 ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 5505120 ubiquitin carboxyl-terminal hydrolase 16 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 5516438 ubiquitin carboxyl-terminal hydrolase 19 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 116614602 ubiquitin carboxyl-terminal hydrolase 20-like K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 5514504 ubiquitin carboxyl-terminal hydrolase 22 isoform X1 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 5504841 ubiquitin carboxyl-terminal hydrolase 25 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 5521682 ubiquitin carboxyl-terminal hydrolase 37 isoform X1 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 5516600 ubiquitin carboxyl-terminal hydrolase 30 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 5506112 ubiquitin carboxyl-terminal hydrolase 31 isoform X1 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 5508249 ubiquitin carboxyl-terminal hydrolase 34 isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 5512546 ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 5503887 ubiquitin carboxyl-terminal hydrolase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 5515799 ubiquitin carboxyl-terminal hydrolase 40 isoform X1 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 116619961 ubiquitin carboxyl-terminal hydrolase 47-like K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 116618122 ubiquitin carboxyl-terminal hydrolase 48-like K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
C OTU
D 5516055 ubiquitin thioesterase OTUB1 isoform X1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 5505716 OTU domain-containing protein 3 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 5516290 OTU domain-containing protein 5 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 5497545 OTU domain-containing protein 5-A K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 5499325 OTU domain-containing protein 5 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 5517998 deubiquitinase OTUD6B isoform X1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 5502067 OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 5510450 tumor necrosis factor alpha-induced protein 3 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 5501944 deubiquitinating protein VCIP135 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 5519776 ubiquitin thioesterase ZRANB1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 5519422 ataxin-3 isoform X2 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 5497969 ataxin-3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 5509641 josephin-like protein K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 5504355 ubiquitin carboxyl-terminal hydrolase MINDY-1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 5509961 probable ubiquitin carboxyl-terminal hydrolase MINDY-4 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 116621155 probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 5504991 probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 5499522 ubiquitin carboxyl-terminal hydrolase MINDY-3 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 5514300 ubiquitin carboxyl-terminal hydrolase MINDY-3 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 5506613 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 116603519 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 5517190 histone H2A deubiquitinase MYSM1 isoform X1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 5516833 MPN domain-containing protein K24173 MPND; MPN domain-containing protein
D 5518465 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 5517062 STAM-binding protein isoform X1 K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 5503258 deubiquitinase DESI2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 5503461 zinc finger-containing ubiquitin peptidase 1 isoform X1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 5519800 BRCA1-A complex subunit Abraxas 1 isoform X1 K20799 FAM175B; BRISC complex subunit Abro1
D 5507658 BRISC and BRCA1-A complex member 1 isoform X1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 5506613 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 116603519 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 5504437 BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 5521263 sentrin-specific protease 1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 5509884 sentrin-specific protease 6 isoform X2 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 5520400 sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 5512201 ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 5520679 uncharacterized protein LOC5520679 isoform X1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 5517553 SUMO-specific isopeptidase USPL1 isoform X1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 5508297 COP9 signalosome complex subunit 1 K12175 GPS1; COP9 signalosome complex subunit 1
D 5519850 LOW QUALITY PROTEIN: COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 5511834 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 116610742 LOW QUALITY PROTEIN: COP9 signalosome complex subunit 4-like K12178 COPS4; COP9 signalosome complex subunit 4
D 5516569 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 5506802 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 5510050 COP9 signalosome complex subunit 7b K12180 COPS7; COP9 signalosome complex subunit 7
D 5508797 COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024