+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Neodiprion virginianus</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      124303104 activating signal cointegrator 1 complex subunit 3	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      124302358 deoxyribodipyrimidine photo-lyase isoform X1	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        124309063 DNA-3-methyladenine glycosylase-like	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
E        124304702 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        124304873 N-glycosylase/DNA lyase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        124301691 exodeoxyribonuclease	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          124306924 DNA polymerase delta catalytic subunit isoform X1	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
F          124305721 DNA polymerase delta subunit 2	K02328 POLD2; DNA polymerase delta subunit 2 
E        DNA polymerase epsilon complex
F          124303772 DNA polymerase epsilon catalytic subunit 1 isoform X1	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          124308933 DNA polymerase epsilon subunit 2	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          124299229 DNA polymerase epsilon subunit 3	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
F          124301911 DNA polymerase epsilon subunit 4	K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] 
E        124303760 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        124300355 flap endonuclease 1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        124306309 DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
D      Short Patch-BER factors
E        124304387 DNA polymerase beta-like isoform X1	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
E        124297698 DNA ligase 3 isoform X1	K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] 
D      Other BER factors
E        124302128 probable tyrosyl-DNA phosphodiesterase	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        124307619 aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        124300332 uncharacterized protein F21D5.5 isoform X1	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        124306795 high mobility group protein DSP1-like isoform X1	K10802 HMGB1; high mobility group protein B1 
E        124299085 poly [ADP-ribose] polymerase-like	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          124308045 DNA repair protein complementing XP-C cells homolog isoform X1	K10838 XPC; xeroderma pigmentosum group C-complementing protein 
F          124307349 UV excision repair protein RAD23 homolog B	K10839 RAD23; UV excision repair protein RAD23 
E        Cul4-DDB2 complex
F          124306744 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          124307051 RING-box protein 1-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          124299096 cullin-4A isoform X1	K10609 CUL4; cullin 4 
F          124309290 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          124309206 DNA-directed RNA polymerase II subunit RPB1	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          124303494 DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          124305188 DNA-directed RNA polymerase II subunit RPB3 isoform X1	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          124308876 DNA-directed RNA polymerases I, II, and III subunit RPABC1	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          124297728 DNA-directed RNA polymerases I, II, and III subunit RPABC2	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          124302361 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          124308558 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1	K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 
F          124301789 DNA-directed RNA polymerase II subunit RPB9	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          124298665 DNA-directed RNA polymerases I, II, and III subunit RPABC5	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          124301166 DNA-directed RNA polymerase II subunit RPB11	K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 
F          124306414 DNA-directed RNA polymerases I, II, and III subunit RPABC4	K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 
E        Cul4-CSA complex
F          124306744 RING-box protein 1A	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          124307051 RING-box protein 1-like	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          124299096 cullin-4A isoform X1	K10609 CUL4; cullin 4 
F          124309290 DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
E        Other TCR factor
F          124304845 DNA excision repair protein ERCC-6-like isoform X1	K10841 ERCC6; DNA excision repair protein ERCC-6 
F          124301840 transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        124297884 general transcription and DNA repair factor IIH helicase subunit XPB	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        124308693 general transcription and DNA repair factor IIH helicase subunit XPD isoform X1	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        124307701 general transcription factor IIH subunit 1 isoform X1	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        124304567 general transcription factor IIH subunit 2	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        124304510 general transcription factor IIH subunit 3 isoform X1	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        124306240 general transcription factor IIH subunit 4 isoform X1	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        124310456 general transcription factor IIH subunit 5	K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit 
E        124307679 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        124302591 cyclin-H isoform X1	K06634 CCNH; cyclin H 
E        124305473 CDK-activating kinase assembly factor MAT1	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        124305484 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        124300338 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        124298223 replication protein A 14 kDa subunit-like	K10740 RPA3; replication factor A3 
D      Other NER factors
E        124309355 DNA repair protein complementing XP-A cells homolog isoform X1	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        124301401 DNA excision repair protein ERCC-1 isoform X1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        124302928 DNA repair endonuclease XPF isoform X1	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        124306309 DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        124307113 MMS19 nucleotide excision repair protein homolog	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        124304319 cullin-3-A isoform X1	K03869 CUL3; cullin 3 
E        124308649 cullin-5	K10612 CUL5; cullin 5 
E        124301406 elongin-C	K03872 ELOC; elongin-C 
E        124308166 elongin-B	K03873 ELOB; elongin-B 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        124309635 DNA mismatch repair protein Msh2 isoform X1	K08735 MSH2; DNA mismatch repair protein MSH2 
E        124302954 probable DNA mismatch repair protein Msh6	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        124306284 DNA mismatch repair protein Mlh1 isoform X1	K08734 MLH1; DNA mismatch repair protein MLH1 
D      DNA polymerase delta complex
E        124306924 DNA polymerase delta catalytic subunit isoform X1	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        124305721 DNA polymerase delta subunit 2	K02328 POLD2; DNA polymerase delta subunit 2 
D      RPA (replication factor A)
E        124305484 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        124300338 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        124298223 replication protein A 14 kDa subunit-like	K10740 RPA3; replication factor A3 
D      RFC (replication factor C)
E        124305396 replication factor C subunit 1 isoform X1	K10754 RFC1; replication factor C subunit 1 
E        124302515 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
E        124305002 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
E        124302081 replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
E        124303208 replication factor C subunit 3 isoform X1	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        124303760 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        124306795 high mobility group protein DSP1-like isoform X1	K10802 HMGB1; high mobility group protein B1 
E        124306309 DNA ligase 1 isoform X1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        124308660 double-strand break repair protein MRE11 isoform X1	K10865 MRE11; double-strand break repair protein MRE11 
E        124297451 DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA1-core complex
D      BRCA1-A complex
E        124299733 BRISC and BRCA1-A complex member 2-like isoform X1	K12173 BRE; BRCA1-A complex subunit BRE 
E        124302571 lys-63-specific deubiquitinase BRCC36-like	K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
D      BRCA1-B complex
D      BRCA1-C complex
E        124308660 double-strand break repair protein MRE11 isoform X1	K10865 MRE11; double-strand break repair protein MRE11 
E        124297451 DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      BRCA complex
E        124308761 breast cancer type 2 susceptibility protein homolog isoform X1	K08775 BRCA2; breast cancer 2 susceptibility protein 
E        124309062 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        124309062 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
E        124303121 DNA repair protein RAD51 homolog 3-like isoform X1	K10870 RAD51L2; RAD51-like protein 2 
E        124305906 DNA repair protein RAD51 homolog 4	K10871 RAD51L3; RAD51-like protein 3 
E        124300268 DNA repair protein XRCC2 isoform X1	K10879 XRCC2; DNA-repair protein XRCC2 
E        124303022 DNA repair protein XRCC3-like isoform X1	K10880 XRCC3; DNA-repair protein XRCC3 
D      Rad52 family proteins
D      Rad54 family proteins
E        124305068 DNA repair and recombination protein RAD54-like isoform X1	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        124297119 ATP-dependent DNA helicase Q1-like	K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] 
E        124297550 ATP-dependent DNA helicase Q4 isoform X1	K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        124308020 DNA topoisomerase 3-beta-1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        124303551 DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        124300536 recQ-mediated genome instability protein 1-like isoform X1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      RPA (replication factor A)
E        124305484 replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        124300338 replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        124298223 replication protein A 14 kDa subunit-like	K10740 RPA3; replication factor A3 
D      Protein phosphatase 4
E        124298033 serine/threonine-protein phosphatase 4 catalytic subunit	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        124298531 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1	K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 
E        124308404 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
D      AP-5 complex
D      SMC5-SMC6 complex
E        124303130 structural maintenance of chromosomes protein 5 isoform X1	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        124304357 structural maintenance of chromosomes protein 6	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        124297127 non-structural maintenance of chromosomes element 1 homolog	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        124299729 E3 SUMO-protein ligase NSE2-like	K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] 
E        124298638 non-structural maintenance of chromosomes element 3 homolog isoform X1	K22823 NSMCE3; non-structural maintenance of chromosomes element 3 
D      Other HR factors
E        124307845 crossover junction endonuclease EME1 isoform X1	K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] 
E        124307095 exonuclease 3'-5' domain-containing protein 2	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        124305879 crossover junction endonuclease MUS81 isoform X1	K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] 
E        124298245 26S proteasome complex subunit SEM1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        124301061 structure-specific endonuclease subunit slx1	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        124300218 flap endonuclease GEN	K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] 
E        124301372 spatacsin isoform X1	K19026 SPG11; spatacsin 
E        124307364 mortality factor 4-like protein 1 isoform X1	K11339 MORF4L1; mortality factor 4-like protein 1 
E        124303280 fidgetin-like protein 1 isoform X1	K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] 
E        124308522 uncharacterized protein LOC124308522 isoform X1	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        124308523 uncharacterized protein LOC124308523	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        124308735 uncharacterized protein LOC124308735 isoform X1	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        124304522 heat shock factor 2-binding protein-like isoform X1	K25791 HSF2BP; heat shock factor 2-binding protein 
E        124298899 tonsoku-like protein isoform X1	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
E        124309362 biorientation of chromosomes in cell division protein 1-like 1	K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 
E        124303320 Werner Syndrome-like exonuclease isoform X1	K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-] 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
E        124305387 X-ray repair cross-complementing protein 6 isoform X1	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        124308232 X-ray repair cross-complementing protein 5-like	K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 
E        124302050 DNA-dependent protein kinase catalytic subunit-like isoform X1	K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] 
D      MRX complex
E        124308660 double-strand break repair protein MRE11 isoform X1	K10865 MRE11; double-strand break repair protein MRE11 
E        124297451 DNA repair protein RAD50-like	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
E        124309356 DNA ligase 4-like isoform X1	K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] 
E        124308593 DNA repair protein XRCC4-like	K10886 XRCC4; DNA-repair protein XRCC4 
D      X-family DNA polymerases
E        124304387 DNA polymerase beta-like isoform X1	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
D      Other NHEJ factors
E        124307619 aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
C    FA (Fanconi anemia) pathway
D      FA core complex
E        124302712 uncharacterized protein LOC124302712 isoform X1	K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] 
D      FA core complex binding factors
E        124305030 ubiquitin-conjugating enzyme E2 T-like isoform X1	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        124308020 DNA topoisomerase 3-beta-1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        124303551 DNA topoisomerase 3-alpha isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        124300536 recQ-mediated genome instability protein 1-like isoform X1	K10990 RMI1; RecQ-mediated genome instability protein 1 
D      FANCD2-I complex
E        124302160 Fanconi anemia group I protein	K10895 FANCI; fanconi anemia group I protein 
D      Downstream FA components
E        124308761 breast cancer type 2 susceptibility protein homolog isoform X1	K08775 BRCA2; breast cancer 2 susceptibility protein 
D      Other FA pathway factors
E        124301936 fanconi-associated nuclease 1-like isoform X1	K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] 
E        124309062 DNA repair protein RAD51 homolog A	K04482 RAD51; DNA repair protein RAD51 
E        124303121 DNA repair protein RAD51 homolog 3-like isoform X1	K10870 RAD51L2; RAD51-like protein 2 
E        124305740 WD repeat-containing protein 48	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        124299997 serine/threonine-protein phosphatase 6 catalytic subunit	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        124297518 serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1	K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 
E        124305535 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1	K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 
D      Ubiquitin ligases
E        124300368 E3 ubiquitin-protein ligase HERC2	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        124303480 telomerase Cajal body protein 1 isoform X1	K23314 WRAP53; telomerase Cajal body protein 1 
E        124297433 gastrulation defective protein 1 homolog	K24752 WDR70; WD repeat-containing protein 70 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      124308957 DNApol-eta	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      124303387 DNA polymerase iota	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      124307203 DNA repair protein REV1 isoform X1	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
C    A-family DNA polymerase
C    Rad6 epistasis group
D      124302964 ubiquitin-conjugating enzyme E2-17 kDa isoform X1	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      124298042 ubiquitin-conjugating enzyme E2 variant 2	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      124306194 ubiquitin-conjugating enzyme E2 N isoform X1	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      124303760 proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
D      124309547 DNA-dependent metalloprotease dvc-1 isoform X1	K24051 SPRTN; SprT-like domain-contaning protein Spartan 
D      124303043 uncharacterized protein LOC124303043	K26957 GCNA; germ cell nuclear acidic protein 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      124299755 cell cycle checkpoint control protein RAD9A	K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] 
D      124305475 checkpoint protein HUS1	K10903 HUS1; HUS1 checkpoint protein 
D      124299051 cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      124302219 cell cycle checkpoint protein RAD17 isoform X1	K06662 HRAD17; cell cycle checkpoint protein 
D      124302515 replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
D      124305002 replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
D      124302081 replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
D      124303208 replication factor C subunit 3 isoform X1	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      124299051 cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      124301345 protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      124303134 protein TIPIN homolog	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
C    Triple T complex
D      124296805 TELO2-interacting protein 1 homolog	K20403 TTI1; TELO2-interacting protein 1 
C    BAG6-UBL4A-GET4 complex
D      124302175 ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      124297340 Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      124305096 serine/threonine-protein kinase ATR-like isoform X1	K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] 
D      124301184 serine-protein kinase ATM isoform X1	K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
D      124299282 serine/threonine-protein kinase grp	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      124305199 ovarian-specific serine/threonine-protein kinase Lok	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      124308162 M-phase inducer phosphatase-like isoform X1	K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
D      124298685 14-3-3 protein zeta isoform X1	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      124300588 14-3-3 protein epsilon isoform X1	K06630 YWHAE; 14-3-3 protein epsilon 
D      124303543 wee1-like protein kinase isoform X1	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      124304078 wee1-like protein kinase	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      124304988 plastin-2 isoform X1	K17336 PLS3; plastin-3 
D      124310360 protein downstream neighbor of son homolog isoform X1	K22422 DONSON; protein downstream neighbor of Son 
D      124299366 vacuolar protein sorting-associated protein 4	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      124308873 abscission/NoCut checkpoint regulator	K24778 ZFYVE19; abscission/NoCut checkpoint regulator 
D      124309399 replication stress response regulator SDE2	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      124306952 DNA-directed primase/polymerase protein-like	K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] 
C    Nucleases
D      124298101 uncharacterized protein LOC124298101	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
D      124299228 uncharacterized protein LOC124299228	K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] 
C    Helicases
D      124306962 helicase POLQ-like isoform X1	K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] 
C    PSO4 complex
D      124300461 pre-mRNA-processing factor 19	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      124298118 cell division cycle 5-like protein	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      124307850 pre-mRNA-splicing factor SPF27	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
D      124304654 pleiotropic regulator 1 isoform X1	K12862 PLRG1; pleiotropic regulator 1 
C    Modulation of nucleotide pools
D      124305694 oxidized purine nucleoside triphosphate hydrolase-like isoform X1	K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] 
D      124303244 8-oxo-dGDP phosphatase NUDT18	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      124301839 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      124300519 ribonucleoside-diphosphate reductase large subunit isoform X1	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      124304719 ribonucleoside-diphosphate reductase subunit M2 isoform X1	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
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A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      124302358 deoxyribodipyrimidine photo-lyase isoform X1	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        124304702 single-strand selective monofunctional uracil DNA glycosylase	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        124309063 DNA-3-methyladenine glycosylase-like	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        124308292 single-stranded DNA-binding protein, mitochondrial isoform X1	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      124308292 single-stranded DNA-binding protein, mitochondrial isoform X1	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      124301839 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
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#Last updated: March 29, 2024