+F Repair protein KO
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DNA Repair and Recombination Proteins - Oleispira antarctica
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OLEAN_C21990 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OLEAN_C23760 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E OLEAN_C03400 A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OLEAN_C30500 nth; DNA-(Apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D OLEAN_C29970 mutT; Mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OLEAN_C38510 dut; Deoxyuridine 5\'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OLEAN_C07110 Aminoacyl-tRNA synthetase, class I family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D OLEAN_C21990 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OLEAN_C05430 Deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E OLEAN_C23760 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E OLEAN_C03400 A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OLEAN_C38460 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E OLEAN_C30500 nth; DNA-(Apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E OLEAN_C19190 xthA; Exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E OLEAN_C38570 Exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E OLEAN_C25590 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E OLEAN_C23000 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E OLEAN_C00340 polA; probable DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E OLEAN_C02720 uvrA; UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A) K03701 uvrA; excinuclease ABC subunit A
E OLEAN_C14190 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E OLEAN_C18850 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E OLEAN_C10610 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OLEAN_C38910 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OLEAN_C00340 polA; probable DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E OLEAN_C23000 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F OLEAN_C02370 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F OLEAN_C02380 rpoC; DNA-directed RNA polymerase subunit beta\' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F OLEAN_C02690 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F OLEAN_C38600 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F OLEAN_C15440 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E OLEAN_C28280 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E OLEAN_C35750 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E OLEAN_C21650 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E OLEAN_C28930 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E OLEAN_C36080 Exodeoxyribonuclease VII, small subunit, probable K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E OLEAN_C10050 dnaE; DNA-directed DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E OLEAN_C00020 dnaN; DNA-directed DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E OLEAN_C11840 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E OLEAN_C33000 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E OLEAN_C19960 holB; probable DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E OLEAN_C13430 polC; DNA polymerase III, alpha subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OLEAN_C20430 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OLEAN_C27460 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OLEAN_C38140 Exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OLEAN_C21120 dnaX; DNA-directed DNA polymerase III, tau and gamma subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E OLEAN_C23000 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E OLEAN_C10610 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OLEAN_C38910 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OLEAN_C02750 ssb; similar to single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E OLEAN_C25120 Single-strand binding family protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E OLEAN_C23550 recB; Exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E OLEAN_C23560 recC; Exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E OLEAN_C23540 recD; Exonuclease V alpha-subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E OLEAN_C28270 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA
E OLEAN_C25380 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OLEAN_C25370 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OLEAN_C25390 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E OLEAN_C35940 priA; Primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E OLEAN_C21650 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E OLEAN_C15390 sbcC; Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E OLEAN_C15380 sbcD; Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E OLEAN_C28270 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA
E OLEAN_C34200 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E OLEAN_C00030 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF
E OLEAN_C38650 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E OLEAN_C25590 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E OLEAN_C14640 recO; DNA repair protein RecO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
E OLEAN_C21100 recR; Recombination protein RecR K06187 recR; recombination protein RecR
E OLEAN_C06830 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E OLEAN_C25380 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OLEAN_C25370 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OLEAN_C25390 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E OLEAN_C15810 Type III restriction family enzyme, res subunit K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E OLEAN_C15390 sbcC; Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E OLEAN_C15380 sbcD; Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F OLEAN_C13890 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F OLEAN_C00040 gyrB; DNA gyrase B, DNA topoisomerase (ATP-hydrolysing),type IIA, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F OLEAN_C15260 topA; DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F OLEAN_C38710 hupA; DNA-binding protein HU-alpha K05787 hupA; DNA-binding protein HU-alpha
F OLEAN_C20490 Putative bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F OLEAN_C25590 recJ; Single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F OLEAN_C14640 recO; DNA repair protein RecO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
F OLEAN_C21100 recR; Recombination protein RecR K06187 recR; recombination protein RecR
F OLEAN_C23000 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F OLEAN_C06080 Factor for inversion stimulation Fis, transcriptional activator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F OLEAN_C13780 ihfA; Integration host factor subunit alpha (IHF-alpha) K04764 ihfA; integration host factor subunit alpha
F OLEAN_C13960 ihfB; probable Integration host factor subunit beta (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F OLEAN_C21650 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F OLEAN_C17580 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F OLEAN_C21590 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F OLEAN_C02720 uvrA; UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A) K03701 uvrA; excinuclease ABC subunit A
F OLEAN_C14190 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D OLEAN_C09760 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D OLEAN_C28270 recA; Protein RecA (Recombinase A) K03553 recA; recombination protein RecA
D OLEAN_C16960 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D OLEAN_C06830 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D OLEAN_C02010 polB; DNA-directed DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D OLEAN_C02750 ssb; similar to single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D OLEAN_C25120 Single-strand binding family protein K03111 ssb; single-strand DNA-binding protein
D OLEAN_C28260 recX; RecA regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D OLEAN_C37330 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D OLEAN_C20750 Helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D OLEAN_C29970 mutT; Mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OLEAN_C38510 dut; Deoxyuridine 5\'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OLEAN_C12600 nrdA__dnaF; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OLEAN_C22440 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OLEAN_C12590 nrdB; Ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025