+D Receptor KO #

  G Protein-Coupled Receptors - Octopus bimaculoides (California two-spot octopus)

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ARhodopsin family B Biogenic amine C Acetylcholine (muscarinic) D 106871529 dopamine receptor 2 K04131 CHRM3; muscarinic acetylcholine receptor M3 D 106874556 trace amine-associated receptor 2 K04134 CHRMN; muscarinic acetylcholine receptor C Adrenaline D 106874449 alpha-1A adrenergic receptor K04136 ADRA1B; adrenergic receptor alpha-1B C Dopamine D 106872726 dopamine receptor 1 K04144 DRD1; dopamine receptor D1 D 106868231 D(2) dopamine receptor K04145 DRD2; dopamine receptor D2 D 106867627 dopamine receptor 2 K04148 DRD1N; dopamine receptor D1-like C Dopamine and ecdysteroid D 106877790 G-protein coupled receptor 52 K22919 DopEcR; dopamine/ecdysteroid receptor C Histamine D 106874438 histamine H2 receptor K04150 HRH2; histamine receptor H2 D 106883050 histamine H2 receptor-like K04150 HRH2; histamine receptor H2 D 106871697 histamine H3 receptor K04151 HRH3; histamine receptor H3 C Octopamine and tryamine D 106870961 octopamine receptor Oamb K04165 Oamb; octopamine receptor D 106867544 alpha-2A adrenergic receptor K22814 Octalpha; octopamine receptor alpha D 106870358 octopamine receptor beta-2R K22790 Octbeta; octopamine receptor beta D 106875033 octopamine receptor K22791 TyrR; tyramine receptor D 106873581 probable G-protein coupled receptor No18 K22815 Oct-TyrR; octopamine/tyramine receptor D 106880758 octopamine receptor 2 K22815 Oct-TyrR; octopamine/tyramine receptor C Serotonin D 106873250 5-hydroxytryptamine receptor 1B K04153 HTR1; 5-hydroxytryptamine receptor 1 D 106875243 5-hydroxytryptamine receptor K04153 HTR1; 5-hydroxytryptamine receptor 1 D 106872573 muscarinic acetylcholine receptor M2 K04157 HTR2; 5-hydroxytryptamine receptor 2 D 106878079 5-hydroxytryptamine receptor 2C K04157 HTR2; 5-hydroxytryptamine receptor 2 D 106869336 5-hydroxytryptamine receptor 4 isoform X2 K04160 HTR4; 5-hydroxytryptamine receptor 4 D 106882749 5-hydroxytryptamine receptor 6 K04162 HTR6; 5-hydroxytryptamine receptor 6 D 106882687 5-hydroxytryptamine receptor 1 K04163 HTR7; 5-hydroxytryptamine receptor 7 C Trace amine B Peptide C Adrenomedullin (G10D) C Adropin C Apelin C Anaphylatoxin C Angiotensin D 106868170 uncharacterized protein LOC106868170 K04166 AGTR1; angiotensin II receptor type 1 C BigLEN C Bombesin D 106877828 neuropeptide CCHamide-1 receptor K04170 BRS3; bombesin receptor subtype-3 C Bradykinin C Cholecystokinin D 106867239 G-protein coupled receptor 54 K04194 CCKAR; cholecystokinin A receptor D 106867240 QRFP-like peptide receptor K04194 CCKAR; cholecystokinin A receptor D 106867950 cholecystokinin receptor K04194 CCKAR; cholecystokinin A receptor D 106867955 arg8-vasotocin receptor K04194 CCKAR; cholecystokinin A receptor D 106867956 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106868662 nematocin receptor 2 K04194 CCKAR; cholecystokinin A receptor D 106868664 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106869404 somatostatin receptor type 2 isoform X1 K04194 CCKAR; cholecystokinin A receptor D 106870483 mesotocin receptor K04194 CCKAR; cholecystokinin A receptor D 106870937 cholecystokinin receptor type A isoform X1 K04194 CCKAR; cholecystokinin A receptor D 106871410 orexin receptor type 2 K04194 CCKAR; cholecystokinin A receptor D 106872657 QRFP-like peptide receptor K04194 CCKAR; cholecystokinin A receptor D 106874780 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106876555 cholecystokinin receptor type A isoform X1 K04194 CCKAR; cholecystokinin A receptor D 106876814 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106877244 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106877991 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106881655 cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor D 106882543 isotocin receptor K04194 CCKAR; cholecystokinin A receptor D 106883812 neuropeptide FF receptor 2 isoform X1 K04194 CCKAR; cholecystokinin A receptor C Endothelin C fMet-Leu-Phe C Follicle stimulating hormone (FSH) C Galanin D 106871605 delta-type opioid receptor K04231 GALR2; galanin receptor 2 D 106873537 galanin receptor 2b K04232 GALR3; galanin receptor 3 D 106873422 allatostatin-A receptor K04233 ASTA-R; allatostatin A receptor C Ghrelin D 106873507 growth hormone secretagogue receptor type 1 K04284 GHSR; growth hormone secretagogue receptor C Gonadotropin-releasing hormone (GnRH) D 106872195 gonadotropin-releasing hormone receptor K04280 GNRHR; gonadotropin-releasing hormone receptor C Lutropin-choriogonadotropic hormone C Melanin-concentrating hormone (MCH) C Melanocortin C Motilin C Neuromedin U D 106868725 pyrokinin-1 receptor K05052 NMUR1; neuromedin U receptor 1 D 106874266 pyrokinin-1 receptor K05052 NMUR1; neuromedin U receptor 1 D 106877850 FMRFamide receptor K05053 NMUR2; neuromedin U receptor 2 C Neuropeptide FF D 106870565 QRFP-like peptide receptor K08375 NPFFR2; neuropeptide FF receptor 2 D 106870661 neuropeptide SIFamide receptor K08375 NPFFR2; neuropeptide FF receptor 2 D 106874026 neuropeptide FF receptor 2 K08375 NPFFR2; neuropeptide FF receptor 2 D 106879040 neuromedin-U receptor 2 K08375 NPFFR2; neuropeptide FF receptor 2 D 106879682 neuropeptide Y receptor type 2 K08375 NPFFR2; neuropeptide FF receptor 2 D 106884237 neuropeptide FF receptor 2 K08375 NPFFR2; neuropeptide FF receptor 2 C Neuropeptide S D 106868179 cardioacceleratory peptide receptor K08376 NPSR1; neuropeptide S receptor D 106869641 gonadotropin-releasing hormone II receptor K08376 NPSR1; neuropeptide S receptor D 106875206 cardioacceleratory peptide receptor K08376 NPSR1; neuropeptide S receptor D 106876599 cardioacceleratory peptide receptor K08376 NPSR1; neuropeptide S receptor D 106877248 neuropeptide S receptor K08376 NPSR1; neuropeptide S receptor C Neuropeptide W / neuropeptide B C Neuropeptide Y D 106867413 neuropeptide Y receptor type 5 K04208 NPY6R; neuropeptide Y receptor type 6 D 106870917 neuropeptide Y receptor type 2 K04209 NPFR; neuropeptide F receptor D 106876592 neuropeptide F receptor isoform X1 K04209 NPFR; neuropeptide F receptor C Neurotensin D 106868661 RYamide receptor K04211 NTSR1; neurotensin receptor 1 C Opioid D 106871985 FMRFamide receptor K04216 OPRL1; nociceptin receptor D 106869253 opioid growth factor receptor-like protein 1 isoform X1 K27951 OGFR; opioid growth factor receptor C Orexigenic neuropeptide QRFP D 106867241 pyroglutamylated RF-amide peptide receptor K08378 QRFPR; pyroglutamylated RFamide peptide receptor C Orexin D 106876384 orexin/Hypocretin receptor type 1 K04238 HCRTR1; hypocretin (orexin) receptor 1 D 106867949 orexin receptor type 2 isoform X1 K04239 HCRTR2; hypocretin (orexin) receptor 2 D 106870482 orexin receptor type 2 K04239 HCRTR2; hypocretin (orexin) receptor 2 D 106870526 orexin receptor type 2 K04239 HCRTR2; hypocretin (orexin) receptor 2 D 106870912 orexin receptor type 2 K04239 HCRTR2; hypocretin (orexin) receptor 2 D 106874907 C5a anaphylatoxin chemotactic receptor 1 K04239 HCRTR2; hypocretin (orexin) receptor 2 C Oxytocin C Prokineticin C Prolactin-releasing peptide (PrRP) C Prosaposin C Relaxin C Somatostatin D 106877242 somatostatin receptor type 2 K22872 ASTC-R; allatostatin C receptor D 106882041 somatostatin receptor type 2 K22872 ASTC-R; allatostatin C receptor C Tachykinin D 106874735 histamine H2 receptor isoform X1 K04224 TACR3; tachykinin receptor 3 D 106880286 tachykinin-like peptides receptor 99D K04224 TACR3; tachykinin receptor 3 D 106883454 QRFP-like peptide receptor K04224 TACR3; tachykinin receptor 3 D 106881736 G-protein coupled receptor 83 isoform X2 K14071 LKR; leucokinin receptor D 106875767 QRFP-like peptide receptor K14072 Rya-R; RYamide receptor D 106875769 QRFP-like peptide receptor isoform X1 K14072 Rya-R; RYamide receptor D 106880835 RYamide receptor K14072 Rya-R; RYamide receptor C Thrombin C Thyrotropin C Thyrotropin-releasing hormone (TRH) D 106868550 FMRFamide receptor K04282 TRHR; thyrotropin-releasing hormone receptor C Urotensin II C Vasopressin D 106877996 cephalotocin receptor 1 K04226 AVPR1A; arginine vasopressin receptor 1A D 106878984 octopressin receptor isoform X1 K04226 AVPR1A; arginine vasopressin receptor 1A D 106882373 cephalotocin receptor 2 K04226 AVPR1A; arginine vasopressin receptor 1A C Neuropeptide receptors D 106869260 sex peptide receptor K26200 SPR; sex peptide receptor D 106873447 FMRFamide receptor K26201 FMRFaR; FMRFamide receptor D 106875459 FMRFamide receptor K26201 FMRFaR; FMRFamide receptor D 106869230 FMRFamide receptor K26202 Proc-R; proctolin receptor D 106872763 FMRFamide receptor K26202 Proc-R; proctolin receptor D 106867137 G-protein coupled receptor dmsr-1 K26203 MsR; myosuppressin receptor D 106868552 G-protein coupled receptor dmsr-1 K26203 MsR; myosuppressin receptor D 106875528 G-protein coupled receptor dmsr-1 K26203 MsR; myosuppressin receptor B Chemokine C CC Chemokine C CXC Chemokine C CX3C Chemokine C C Chemokine C Chemokine like B Base and nucleoside C Purine / pyrimidine C Adenosine D 106872814 adenosine receptor A2b K04267 ADORA2B; adenosine receptor A2b B Lipid C Arachidonylglycine C Bile acid C Cysteinyl leukotriene C Free fatty acid C HETE and oxoETE C Leukotriene C Lysophosphatidic acid C Lysophosphatidylinositol C Lysophosphatidylserine C Oleoylethanolamide C Prostaglandin D 106875962 prostaglandin E2 receptor EP4 subtype K04261 PTGER4; prostaglandin E receptor 4 D 106877104 prostaglandin E2 receptor EP4 subtype K04261 PTGER4; prostaglandin E receptor 4 C Prostacyclin C Sphingolipid C Thromboxane B Vision C Opsin D 106871833 melanopsin-A K04256 OPN3; c-opsin D 106870569 rhodopsin K04255 OPN4; r-opsin D 106876108 ocellar opsin K04255 OPN4; r-opsin D 106878312 rhodopsin K04255 OPN4; r-opsin D 106869476 retinochrome K04253 RRH; visual pigment-like receptor peropsin D 106875959 visual pigment-like receptor peropsin K04253 RRH; visual pigment-like receptor peropsin B Others C Alpha-ketoglutarate C Cannabinoid C Estrogen C Hydroxy-carboxylic acid C L-Tryptophan and L-Phenylalanine D 106867458 probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139 D 106881783 sex peptide receptor-related protein 2 K08428 GPR139; G protein-coupled receptor 139 C Mas proto-oncogene and Mas-related (MRGs) C Melatonin D 106872168 melatonin receptor type 1A K04285 MTNR1A; melatonin receptor type 1A C Oxysterol D 106879000 G-protein coupled receptor 183-A K04305 EBI2; Epstein-Barr virus induced gene 2 C Platelet activating factor C Proton-sensing GPCRs C R-spondin D 106873188 follicle-stimulating hormone receptor K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6 C Super conserved receptor expressed in brain (SREB) D 106867476 probable G protein-coupled receptor 85 K04302 SREB2; super conserved receptor expressed in brain 2 C Trissin D 106867622 trissin receptor K22792 TrissinR; trissin receptor D 106876193 trissin receptor K22792 TrissinR; trissin receptor C Orphan GPCRs / unclassified GPCRs D 106873105 G-protein coupled receptor 22 K04319 GPR22; G protein-coupled receptor 22 D 106877296 melatonin receptor type 1B-B K04287 GPR50; G protein-coupled receptor 50 D 106878532 arg8-vasotocin receptor K08434 GPR150; G protein-coupled receptor 150 D 106883221 G-protein coupled receptor 161 K08439 GPR161; G protein-coupled receptor 161 # ASecretin receptor family B Calcium-regulating peptide C Calcitonin D 106867588 calcitonin gene-related peptide type 1 receptor-like K04576 CALCR; calcitonin receptor D 106870560 calcitonin receptor isoform X1 K04576 CALCR; calcitonin receptor D 106874612 calcitonin receptor K04576 CALCR; calcitonin receptor D 106874704 calcitonin receptor isoform X3 K04576 CALCR; calcitonin receptor D 106876900 calcitonin gene-related peptide type 1 receptor K04576 CALCR; calcitonin receptor D 106867957 calcitonin receptor K04577 CALCRL; calcitonin receptor-like C Parathyroid hormone D 106868068 secretin receptor K04585 PTH1R; parathyroid hormone receptor 1 D 106871086 gastric inhibitory polypeptide receptor isoform X1 K04585 PTH1R; parathyroid hormone receptor 1 D 106875639 secretin receptor isoform X1 K04585 PTH1R; parathyroid hormone receptor 1 D 106884339 calcitonin gene-related peptide type 1 receptor K04585 PTH1R; parathyroid hormone receptor 1 D 106884341 glucagon-like peptide 1 receptor K04585 PTH1R; parathyroid hormone receptor 1 B Hypothalamic hormone C Corticotropin-releasing hormone (CRH) D 106872685 adhesion G-protein coupled receptor G2 K04578 CRHR1; corticotropin releasing hormone receptor 1 D 106870026 corticotropin-releasing factor receptor 2 K04579 CRHR2; corticotropin releasing hormone receptor 2 D 106871453 corticotropin-releasing factor receptor 2 isoform X1 K04579 CRHR2; corticotropin releasing hormone receptor 2 D 106875237 corticotropin-releasing factor receptor 2 isoform X1 K04579 CRHR2; corticotropin releasing hormone receptor 2 C Growth hormone-releasing hormone (GHRH) B Pancreatic peptide C Glucagon B Gut peptide C Gastric inhibitory peptide (GIP) C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP) C Secretin B Others C Receptor activity modifying protein C Methuselah-like proteins (MTH) C Pigment dispersing factor (PDF) D 106874534 calcitonin receptor K22738 PDFR; PDF receptor D 106878352 PDF receptor isoform X1 K22738 PDFR; PDF receptor D 106882345 PDF receptor K22738 PDFR; PDF receptor # AAdhesion receptor family B Cadherin EGF LAG (CELSR) C 106877480 cadherin EGF LAG seven-pass G-type receptor 2 isoform X1 K04600 CELSR1; cadherin EGF LAG seven-pass G-type receptor 1 B EGF-like module-containing mucin-like hormone receptor-like (EMR) B Latrophilin C 106868178 adhesion G protein-coupled receptor L3 K04593 ADGRL2; adhesion G protein-coupled receptor L2 C 106880564 adhesion G protein-coupled receptor L2 isoform X1 K04593 ADGRL2; adhesion G protein-coupled receptor L2 B Brain-specific angiogenesis inhibitor (BAI) B Others C 106881079 adhesion G protein-coupled receptor A3 K08462 ADGRA3; adhesion G protein-coupled receptor A3 # AMetabotropic glutamate receptor family B Glutamate (metabotropic) C 106867234 metabotropic glutamate receptor 3 K04606 GRM3; metabotropic glutamate receptor 3 C 106869985 metabotropic glutamate receptor K04606 GRM3; metabotropic glutamate receptor 3 C 106877299 metabotropic glutamate receptor 8 K04610 GRM8; metabotropic glutamate receptor 8 B GABA C 106869702 uncharacterized protein LOC106869702 K04615 GABBR; gamma-aminobutyric acid type B receptor C 106872098 gamma-aminobutyric acid type B receptor subunit 1 K04615 GABBR; gamma-aminobutyric acid type B receptor B Calcium-sensing C 106873615 metabotropic glutamate receptor 2 K04612 CASR; calcium-sensing receptor B Orphan GPRC5 B Unclassified GPCRs C 106876327 uncharacterized protein LOC106876327 K08469 GPR158; G protein-coupled receptor 158 C 106877599 probable G-protein coupled receptor CG31760 K08469 GPR158; G protein-coupled receptor 158 # AFrizzled / Smoothened family B 106881898 frizzled-1 K02432 FZD1_7; frizzled 1/7 B 106874964 frizzled-4 K02354 FZD4; frizzled 4 B 106871811 frizzled-5 K02375 FZD5_8; frizzled 5/8 B 106883907 frizzled-9 K02842 FZD9_10; frizzled 9/10 B 106882719 smoothened homolog K06226 SMO; smoothened # AOthers B Chemoreception C Olfactory C Taste C Vomeronasal pheromone C Insect odorant and taste D 106874590 uncharacterized protein LOC106874590 isoform X1 K08471 GR; gustatory receptor C Nematode chemoreception C Fungal mating pheromone B Others C Ocular albinism proteins C Neuronostatin D 106881420 protein GPR107 K22985 GPR107; G protein-coupled receptor 107 C Plant Mlo receptors C cAMP signaling D 106884106 cyclic AMP receptor-like protein A K22987 GCR1; cAMP receptor-like G-protein coupled receptor C Bacterial rhodopsin C Orphan GPCRs D 106883095 transmembrane protein adipocyte-associated 1 homolog K22988 TPRA1; transmembrane protein adipocyte-associated 1 D 106882348 integral membrane protein GPR137B K22989 GPR137; integral membrane protein GPR137 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 22, 2025 #
Classification taken and modified from GPCRDB