+F Repair protein KO
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DNA Repair and Recombination Proteins - Afipia carboxidovorans OM5 (Goettingen)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OCA5_c22730 phrB; deoxyribodipyrimidine photolyase PhrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OCA5_c19390 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E OCA5_c11080 mutY; A/G-specific adenine DNA glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OCA5_c01050 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D OCA5_c04240 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c11540 NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c08180 NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c00460 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OCA5_c01070 ada; regulatory protein Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D OCA5_c22730 phrB; deoxyribodipyrimidine photolyase PhrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OCA5_c21820 uracil-DNA glycosylase family protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E OCA5_c27950 uracil-DNA glycosylase family protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E OCA5_c11240 putative uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E OCA5_c32040 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E OCA5_c19390 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E OCA5_c11080 mutY; A/G-specific adenine DNA glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OCA5_c11490 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E OCA5_c00420 mutM; formamidopyrimidine-DNA glycosylase MutM K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E OCA5_c01050 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E OCA5_c17560 xthA2; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E OCA5_c01720 xthA1; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E OCA5_c20070 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E OCA5_c27150 ligA; DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E OCA5_c05750 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E OCA5_c17930 uvrA; excinuclease ABC system, subunit A K03701 uvrA; excinuclease ABC subunit A
E OCA5_c09260 uvrB; uvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E OCA5_c08990 uvrC; uvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E OCA5_c27050 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OCA5_c03540 DNA helicase, UvrD/Rep family protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OCA5_c05750 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E OCA5_c27150 ligA; DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F OCA5_c23420 rpoB; DNA-directed RNA polymerase subunit beta' K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F OCA5_c23410 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F OCA5_c23060 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F OCA5_c21800 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F OCA5_c18210 mfd; transcription-repair-coupling factor Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E OCA5_c03890 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E OCA5_c08730 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E OCA5_c08670 xseA; exodeoxyribonuclease 7 large subunit XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E OCA5_c11870 xseB; exodeoxyribonuclease 7 small subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E OCA5_c20700 dnaE1; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E OCA5_c00020 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E OCA5_c16910 putative DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E OCA5_c01640 putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E OCA5_c19030 putative DNA polymerase III subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E OCA5_c01430 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OCA5_c05950 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E OCA5_c27150 ligA; DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E OCA5_c27050 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OCA5_c03540 DNA helicase, UvrD/Rep family protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OCA5_c24560 ssb2; single-stranded DNA-binding protein Ssb K03111 ssb; single-strand DNA-binding protein
E OCA5_c17950 ssb1; single-stranded DNA-binding protein Ssb K03111 ssb; single-strand DNA-binding protein
E OCA5_pOC16701250 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E OCA5_pOC16700050 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E OCA5_c25520 recA; recombinase A K03553 recA; recombination protein RecA
E OCA5_c08150 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OCA5_c08170 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OCA5_c08140 ruvC; holliday junction DNA nuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E OCA5_c24410 hypothetical protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E OCA5_c33560 priA; primosomal assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E OCA5_c25520 recA; recombinase A K03553 recA; recombination protein RecA
E OCA5_c16660 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E OCA5_c18590 putative ATPase, RecA family protein K04485 radA; DNA repair protein RadA/Sms
E OCA5_c00040 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E OCA5_c18180 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E OCA5_c20070 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E OCA5_c21710 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E OCA5_c05970 recR; recombination protein RecR K06187 recR; recombination protein RecR
E OCA5_c27160 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E OCA5_c08150 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OCA5_c08170 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OCA5_c08140 ruvC; holliday junction DNA nuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E OCA5_c24410 hypothetical protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E OCA5_c00520 addA; double-strand break repair helicase AddA K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E OCA5_c00510 addB; double-strand break repair protein AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E OCA5_c14250 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E OCA5_c13510 DNA helicase, ATP-dependent, Ku type K10979 ku; DNA end-binding protein Ku
E OCA5_c11710 putative ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F OCA5_c17970 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F OCA5_c00050 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F OCA5_c22260 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F OCA5_c21010 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F OCA5_c29420 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F OCA5_c24540 RecT family protein K07455 recT; recombination protein RecT
F OCA5_c20070 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F OCA5_c21710 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F OCA5_c05970 recR; recombination protein RecR K06187 recR; recombination protein RecR
F OCA5_c27150 ligA; DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F OCA5_c10590 putative transcriptional regulatory protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F OCA5_c21410 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F OCA5_c00600 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F OCA5_c17930 uvrA; excinuclease ABC system, subunit A K03701 uvrA; excinuclease ABC subunit A
F OCA5_c09260 uvrB; uvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
F OCA5_c21990 histone-like nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
F OCA5_c22000 histone-like nucleoid-structuring family K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D OCA5_c22350 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D OCA5_c25520 recA; recombinase A K03553 recA; recombination protein RecA
D OCA5_c17250 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D OCA5_c27160 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D OCA5_c27940 hypothetical protein K14160 imuA; protein ImuA
D OCA5_pHCG300240 hypothetical protein K14160 imuA; protein ImuA
D OCA5_c27930 imuB; putative protein ImuB K14161 imuB; protein ImuB
D OCA5_pHCG300250 putative nucleotidyltransferase, UmuC-like protein K14161 imuB; protein ImuB
D OCA5_c27920 dnaE2; error-prone DNA polymerase DnaE K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D OCA5_c24560 ssb2; single-stranded DNA-binding protein Ssb K03111 ssb; single-strand DNA-binding protein
D OCA5_c17950 ssb1; single-stranded DNA-binding protein Ssb K03111 ssb; single-strand DNA-binding protein
D OCA5_pOC16701250 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D OCA5_pOC16700050 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D OCA5_c27980 putative helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D OCA5_c04240 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c11540 NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c08180 NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OCA5_c00460 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OCA5_c13090 nrdJ; vitamin B12-dependent ribonucleotide reductase NrdJ K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OCA5_c13200 nrdA; ribonucleoside-diphosphate reductase alpha subunit NrdA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OCA5_c13190 nrdB; ribonucleoside-diphosphate reductase beta subunit NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024