+F Repair protein KO
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DNA Repair and Recombination Proteins - Oncorhynchus gorbuscha (pink salmon)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 124041236 mgmt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 124036384 alkbh2; DNA oxidative demethylase ALKBH2 isoform X1 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 124039647 alkbh3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 123997956 ascc3; activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 124042089 LOW QUALITY PROTEIN: CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 124036383 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124029709 cyclin-O protein A-like K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 124033426 cyclin-O-like K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 124037006 G/T mismatch-specific thymine DNA glycosylase-like K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 124037008 G/T mismatch-specific thymine DNA glycosylase-like K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 124039580 tdg.1; thymine DNA glycosylase, tandem duplicate 1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 124039602 G/T mismatch-specific thymine DNA glycosylase-like isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 124000343 DNA-3-methyladenine glycosylase-like isoform X1 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 124019462 smug1; single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 123997613 mutyh; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 124017307 methyl-CpG-binding domain protein 4-like K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 124045662 ogg1; N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 124037430 neil1; endonuclease 8-like 1 isoform X1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 123993500 neil3; endonuclease 8-like 3 isoform X1 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 124020653 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 124020659 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 124018456 apex1; DNA-(apurinic or apyrimidinic site) endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 124022501 apex2; DNA-(apurinic or apyrimidinic site) lyase 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 124026226 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 124028086 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 124030766 LOW QUALITY PROTEIN: DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 124036538 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F 123993726 pold3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
F 124002035 pold4; LOW QUALITY PROTEIN: DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 124036039 pole; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 124001745 pole2; DNA polymerase epsilon subunit 2 isoform X1 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 124047958 pole3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 123998939 pole4; DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 124034195 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 124036453 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 123990290 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 124009384 zgc:110269; probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 124009810 lig1; LOW QUALITY PROTEIN: DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 124034208 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 123990643 xndc1; short transient receptor potential channel 2 K10803 XRCC1; DNA-repair protein XRCC1
E 123997638 DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
E 124005444 DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
E 124013070 lig3; DNA ligase 3 isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 124001964 tdp1; tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 124034660 aptx; aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 124003507 aplf; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 124018397 bifunctional polynucleotide phosphatase/kinase isoform X1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 123994012 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 123994796 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 124007019 high mobility group-T protein isoform X1 K10802 HMGB1; high mobility group protein B1
E 124015289 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 124003207 DNA polymerase lambda-like K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 123995200 parp1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 124009230 parp2; poly [ADP-ribose] polymerase 2 K28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]
E 124031247 protein mono-ADP-ribosyltransferase PARP3-like K10798 PARP3_4; protein mono-ADP-ribosyltransferase 3/4 [EC:2.4.2.-]
E 124045973 parp4; protein mono-ADP-ribosyltransferase PARP4 isoform X1 K10798 PARP3_4; protein mono-ADP-ribosyltransferase 3/4 [EC:2.4.2.-]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 124031764 xpc; DNA repair protein complementing XP-C cells K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 123997150 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 123998762 rad23ab; RAD23 homolog A, nucleotide excision repair protein b K10839 RAD23; UV excision repair protein RAD23
F 123998978 LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog A-like K10839 RAD23; UV excision repair protein RAD23
F 123999496 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 124019629 UV excision repair protein RAD23 homolog A-like isoform X1 K10839 RAD23; UV excision repair protein RAD23
F 124048554 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 123993685 caltractin-like isoform X1 K10840 CETN2; centrin-2
F 123994099 cetn4; caltractin K10840 CETN2; centrin-2
F 124011402 caltractin-like K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 124000287 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 124015661 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123993537 cullin-4B-like isoform X1 K10609 CUL4; cullin 4
F 124011679 cullin-4B-like isoform X1 K10609 CUL4; cullin 4
F 124023381 cullin-4A-like K10609 CUL4; cullin 4
F 124028727 cullin-4B-like K10609 CUL4; cullin 4
F 124033937 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 124035910 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 124036968 ddb2; DNA damage-binding protein 2 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 124007827 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 124013576 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 123993440 DNA-directed RNA polymerase II subunit RPB2 isoform X1 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 124010823 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB2-like K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 123999921 polr2c; DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 123992836 polr2d; DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 123999096 polr2eb; DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 123998578 DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 124015619 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 123993757 DNA-directed RNA polymerase II subunit RPB7 isoform X1 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 124010536 polr2g; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 123991081 polr2h; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 123992271 DNA-directed RNA polymerase II subunit RPB9-like K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 124004627 polr2i; DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 124033643 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 124035627 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 123990716 polr2j; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 123999913 DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 124012833 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
F 124042633 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 124000287 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 124015661 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123993537 cullin-4B-like isoform X1 K10609 CUL4; cullin 4
F 124011679 cullin-4B-like isoform X1 K10609 CUL4; cullin 4
F 124023381 cullin-4A-like K10609 CUL4; cullin 4
F 124028727 cullin-4B-like K10609 CUL4; cullin 4
F 124033937 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 124035910 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 124035260 ercc8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 124041476 ercc6; DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6
F 124010936 uvssa; UV-stimulated scaffold protein A K23720 UVSSA; UV-stimulated scaffold protein A
F 123998910 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124015095 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124015315 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124019631 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124026760 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 124018718 general transcription and DNA repair factor IIH helicase subunit XPB-like K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 123993966 ercc2; general transcription and DNA repair factor IIH helicase subunit XPD isoform X1 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 124037465 gtf2h1; general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 124036634 gtf2h2; general transcription factor IIH subunit 2 isoform X1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 124033301 gtf2h3; general transcription factor IIH subunit 3 isoform X1 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 124043146 gtf2h4; general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 123995225 gtf2h5; general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 124033274 cdk7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 124036011 ccnh; cyclin-H isoform X1 K06634 CCNH; cyclin H
E 124046520 mnat1; CDK-activating kinase assembly factor MAT1 isoform X1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 123992728 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 124005678 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 123997576 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 124004844 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 124012654 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 124043343 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 124012825 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 124017146 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 124031333 ercc1; DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 124039310 ercc4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 124018303 LOW QUALITY PROTEIN: DNA excision repair protein ERCC-5-like K10846 ERCC5; DNA excision repair protein ERCC-5
E 124018315 LOW QUALITY PROTEIN: DNA excision repair protein ERCC-5-like K10846 ERCC5; DNA excision repair protein ERCC-5
E 124023159 DNA excision repair protein ERCC-5 homolog K10846 ERCC5; DNA excision repair protein ERCC-5
E 124009810 lig1; LOW QUALITY PROTEIN: DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 124039994 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 124048199 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 124034278 coiled-coil domain-containing protein 117-like K27967 CCDC117; coiled-coil domain-containing protein 117
E 124036359 coiled-coil domain-containing protein 117-like K27967 CCDC117; coiled-coil domain-containing protein 117
E 124034355 probable cytosolic iron-sulfur protein assembly protein ciao1-B isoform X1 K24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1
E 124036261 ciao1; probable cytosolic iron-sulfur protein assembly protein ciao1 isoform X1 K24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1
E 124011082 ciao2a; cytosolic iron-sulfur assembly component 2A K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E 124035823 ciao2b; cytosolic iron-sulfur assembly component 2B K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E 123993123 cullin-3 K03869 CUL3; cullin 3
E 124005722 cullin-3-like isoform X1 K03869 CUL3; cullin 3
E 124009558 cullin-3-like K03869 CUL3; cullin 3
E 124041642 cullin-3 isoform X1 K03869 CUL3; cullin 3
E 123992832 cullin-5 isoform X1 K10612 CUL5; cullin 5
E 123998916 cullin-5-like isoform X1 K10612 CUL5; cullin 5
E 124005536 cullin-5-like K10612 CUL5; cullin 5
E 124012673 cullin-5-like isoform X1 K10612 CUL5; cullin 5
E 123990307 elongin-C K03872 ELOC; elongin-C
E 124029060 elongin-C-like K03872 ELOC; elongin-C
E 124039085 elongin-C K03872 ELOC; elongin-C
E 123999122 elongin-B isoform X1 K03873 ELOB; elongin-B
E 124015158 elongin-B K03873 ELOB; elongin-B
E 124012197 elongin-A-like K15076 ELOA; elongin-A
E 124039361 eloal; elongin A, like K15076 ELOA; elongin-A
E 124002383 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 124027753 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 124033037 LOW QUALITY PROTEIN: ubiquitin-associated protein 2-like K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 124040051 msh2; DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 124034012 msh3; DNA mismatch repair protein Msh3 isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3
E 124040307 msh6; DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 124041854 pms1; PMS1 protein homolog 1 K10864 PMS1; DNA mismatch repair protein PMS1
E 124041456 mlh1; DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 124040197 LOW QUALITY PROTEIN: mismatch repair endonuclease PMS2-like K10858 PMS2; DNA mismatch repair protein PMS2
E 124046463 mlh3; DNA mismatch repair protein Mlh3 isoform X1 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 124026226 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 124028086 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 124030766 LOW QUALITY PROTEIN: DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 124036538 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E 123993726 pold3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
E 124002035 pold4; LOW QUALITY PROTEIN: DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 123992728 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 124005678 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 123997576 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 124004844 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 124012654 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 124043343 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 124024854 rfc1; replication factor C subunit 1 isoform X1 K10754 RFC1; replication factor C subunit 1
E 124027425 LOW QUALITY PROTEIN: replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 123996933 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 124011721 rfc2; replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 124037786 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
E 123995226 rfc3; LOW QUALITY PROTEIN: replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 124036588 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 124034195 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 124036453 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 124041293 exo1; exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 123994012 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 123994796 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 124007019 high mobility group-T protein isoform X1 K10802 HMGB1; high mobility group protein B1
E 124015289 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 124009810 lig1; LOW QUALITY PROTEIN: DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 124033554 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
E 124035004 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 123992540 mre11a; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123999240 rad50; DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 123998264 nibrin-like isoform X1 K10867 NBN; nibrin
E 124017030 nibrin-like isoform X1 K10867 NBN; nibrin
D BRCA1-core complex
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 124047459 bard1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 124000049 BRCA1-A complex subunit Abraxas 1 K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 124048741 abraxas1; LOW QUALITY PROTEIN: BRCA1-A complex subunit Abraxas 1 K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 123999687 BRCA1-A complex subunit RAP80-like isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 124011000 BRCA1-A complex subunit RAP80-like isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 123996667 babam1; BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 124046235 babam2; BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE
E 124007176 lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E 124007823 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 123992813 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 124039746 topbp1; DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 124039725 rbbp8; DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 123992540 mre11a; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123999240 rad50; DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 123998264 nibrin-like isoform X1 K10867 NBN; nibrin
E 124017030 nibrin-like isoform X1 K10867 NBN; nibrin
D BRCA complex
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 123994837 brca2; breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 123990826 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 123995151 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 123990826 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 123995151 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 123990916 rad51b; DNA repair protein RAD51 homolog 2 isoform X1 K10869 RAD51L1; RAD51-like protein 1
E 123999780 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 124011253 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 124013083 rad51d; DNA repair protein RAD51 homolog 4 isoform X1 K10871 RAD51L3; RAD51-like protein 3
E 123990272 xrcc2; DNA repair protein XRCC2 isoform X1 K10879 XRCC2; DNA-repair protein XRCC2
E 123990865 xrcc3; DNA repair protein XRCC3 isoform X1 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 123992708 rad52; DNA repair protein RAD52 homolog K10873 RAD52; DNA repair and recombination protein RAD52
E 124000126 rdm1; RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E 123996742 rad54l; DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 124003191 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 124027944 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 124031762 helicase ARIP4-like isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 124046858 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 123998299 DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
E 124017055 DNA repair and recombination protein RAD54B-like isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 124014014 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 124019225 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 123989483 wrn; LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase homolog K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 124036418 blm; Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 124012333 ATP-dependent DNA helicase Q4-like K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 124015259 recql5; ATP-dependent DNA helicase Q5 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 124036418 blm; Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 124019945 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124034698 top3b; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124034549 rmi1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 123992728 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 124005678 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 123997576 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 124004844 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 124012654 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
E 124043343 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 124000787 serine/threonine-protein phosphatase 4 catalytic subunit B K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 124037942 serine/threonine-protein phosphatase 4 catalytic subunit B K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 123990423 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 124002541 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 124025943 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 124038969 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 124003089 serine/threonine-protein phosphatase 4 regulatory subunit 2-B-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 124031507 ppp4r2b; serine/threonine-protein phosphatase 4 regulatory subunit 2-B isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 124032042 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 124045886 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 123990539 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 123994940 serine/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 124038305 serine/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 124041177 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 123990868 ppp4r4; serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 124003329 ap5b1; AP-5 complex subunit beta-1 isoform X1 K19022 AP5B1; AP-5 complex subunit beta-1
E 124046485 ap5m1; AP-5 complex subunit mu-1 K19023 AP5M1; AP-5 complex subunit mu-1
E 124045372 ap5s1; AP-5 complex subunit sigma-1 K19024 AP5S1; AP-5 complex subunit sigma-1
E 124018518 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
E 124020993 LOW QUALITY PROTEIN: AP-5 complex subunit zeta-1-like K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 124048989 smc5; structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 123995213 si:dkey-119f1.1; structural maintenance of chromosomes protein 6-like isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 124046706 smc6; structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 123991519 protein LRATD1-like isoform X1 K22805 FAM84A; protein FAM84A
E 123994374 LOW QUALITY PROTEIN: protein LRATD1-like K22805 FAM84A; protein FAM84A
E 124029165 protein LRATD1-like K22805 FAM84A; protein FAM84A
E 123999649 non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 124015144 non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 124017643 E3 SUMO-protein ligase NSE2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 124023151 E3 SUMO-protein ligase NSE2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 124023319 E3 SUMO-protein ligase NSE2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 124045385 ndnl2; necdin-like 2 K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 124047522 non-structural maintenance of chromosomes element 4 homolog A-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 124036001 slf1; SMC5-SMC6 complex localization factor protein 1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 124038388 uncharacterized protein LOC124038388 isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
E 124040329 uncharacterized protein LOC124040329 isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
E 124010396 simc1; SUMO-interacting motif-containing protein 1 K28408 SIMC1; SUMO-interacting motif-containing protein 1
D Other HR factors
E 124038451 eme1; crossover junction endonuclease EME1 isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 124001689 exonuclease 3'-5' domain-containing protein 2-like isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 124046803 exd2; exonuclease 3'-5' domain-containing protein 2 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 124008855 mus81; crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 124013318 sem1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 124043242 26S proteasome complex subunit SEM1-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 124047772 swi5; DNA repair protein SWI5 homolog isoform X1 K10991 SWI5; DNA repair protein Swi5/Sae3
E 124041250 sfr1; swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 124008270 slx1b; structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 124015555 slx4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 123995214 flap endonuclease GEN homolog 1 isoform X1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 124039927 spg11; spatacsin isoform X1 K19026 SPG11; spatacsin
E 124046796 zfyve26; LOW QUALITY PROTEIN: zinc finger FYVE domain-containing protein 26 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 123995634 RAD51-associated protein 1-like K20778 RAD51AP1; RAD51-associated protein 1
E 124014175 LOW QUALITY PROTEIN: RAD51-associated protein 1-like K20778 RAD51AP1; RAD51-associated protein 1
E 124034492 RAD51-associated protein 1-like K20778 RAD51AP1; RAD51-associated protein 1
E 124019831 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 124019834 LOW QUALITY PROTEIN: mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 124033436 samhd1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 124045591 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 124038129 fignl1; fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 124041756 spidr; DNA repair-scaffolding protein K22806 SPIDR; DNA repair-scaffolding protein
E 124012844 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 124017635 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 124042634 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 124024494 brat1; BRCA1-associated ATM activator 1 K23112 BRAT1; BRCA1-associated ATM activator 1
E 124042210 cfap410; cilia and flagella associated protein 410 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 123997050 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 124037694 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 123998602 zswim7; zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 123999040 uncharacterized protein LOC123999040 K25771 SWSAP1; ATPase SWSAP1
E 124019634 uncharacterized protein LOC124019634 K25771 SWSAP1; ATPase SWSAP1
E 123999765 LOW QUALITY PROTEIN: BRCA2-interacting transcriptional repressor EMSY-like K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 124013220 emsy; BRCA2-interacting transcriptional repressor EMSY isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 124011631 heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein
E 124005929 mms22l; protein MMS22-like K26125 MMS22L; protein MMS22-like
E 124046279 tonsl; tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 123993561 bod1l1; biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 123994487 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
E 123999361 homologous recombination OB-fold protein-like isoform X1 K27803 HROB; homologous recombination OB-fold protein
E 124001503 mcm8; DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
E 123990729 DNA helicase MCM9-like isoform X1 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 124037298 X-ray repair cross-complementing protein 5-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 124044310 xrcc5; X-ray repair cross-complementing protein 5 isoform X1 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 123991347 prkdc; DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 123992540 mre11a; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123999240 rad50; DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 124008630 lig4; DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 124006823 xrcc4; DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4
E 124033407 DNA repair protein XRCC4-like isoform X1 K10886 XRCC4; DNA-repair protein XRCC4
E 124019581 non-homologous end-joining factor 1-like K10980 NHEJ1; non-homologous end-joining factor 1
E 124030123 non-homologous end-joining factor 1-like K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 124003207 DNA polymerase lambda-like K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 123989341 polm; DNA-directed DNA/RNA polymerase mu isoform X1 K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 124037185 DNA nucleotidylexotransferase isoform X1 K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 124040812 dntt; DNA nucleotidylexotransferase isoform X1 K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 124034208 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 124034660 aptx; aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 124003507 aplf; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 124021605 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 124022384 protein artemis-like K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 124023238 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 123997307 tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 124042640 tdp2b; tyrosyl-DNA phosphodiesterase 2 isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 124039785 smchd1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 123997205 PWWP domain-containing DNA repair factor 3B-like isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 124041610 PWWP domain-containing DNA repair factor 3B-like isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 124034071 paxx; protein PAXX isoform X1 K25772 PAXX; protein PAXX
E 124034944 protein PAXX-like K25772 PAXX; protein PAXX
E 124034201 si:ch211-127m7.2; uncharacterized protein si:ch211-127m7.2 K26155 CYREN; cell cycle regulator of non-homologous end joining
E 124020639 jmjd8; jmjC domain-containing protein 8 K25792 JMJD8; jumonji domain-containing protein 8
E 124041338 shld2; shieldin complex subunit 2 K26129 SHLD2; shieldin complex subunit 2
E 124033193 zgc:101664; shieldin complex subunit 3 K26130 SHLD3; shieldin complex subunit 3
E 123993552 BEN domain-containing protein 4-like isoform X1 K27845 BEND4; BEN domain-containing protein 4
C FA (Fanconi anemia) pathway
D FA core complex
E 124037776 Fanconi anemia group A protein-like isoform X1 K10888 FANCA; fanconi anemia group A protein
E 124045918 fancb; LOW QUALITY PROTEIN: Fanconi anemia group B protein K10889 FANCB; fanconi anemia group B protein
E 124034122 fancc; Fanconi anemia group C protein K10890 FANCC; fanconi anemia group C protein
E 124023189 fance; Fanconi anemia group E protein K10892 FANCE; fanconi anemia group E protein
E 124036982 fancf; Fanconi anemia group F protein isoform X1 K10893 FANCF; fanconi anemia group F protein
E 124033281 fancg; Fanconi anemia group G protein isoform X1 K10894 FANCG; fanconi anemia group G protein
E 124020844 fancl; E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 124046252 fancm; Fanconi anemia group M protein isoform X1 K10896 FANCM; fanconi anemia group M protein
E 124033836 faap24; Fanconi anemia core complex-associated protein 24 K10898 FAAP24; fanconi anemia-associated protein
E 124040205 faap100; Fanconi anemia core complex-associated protein 100 isoform X1 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
D FA core complex binding factors
E 123991171 transcription factor HES-1-B-like K06054 HES1; hairy and enhancer of split 1
E 123997720 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 124010117 transcription factor HES-1-B-like K06054 HES1; hairy and enhancer of split 1
E 124021836 transcription factor HES-4-B-like isoform X1 K06054 HES1; hairy and enhancer of split 1
E 124041002 transcription factor HES-1-B-like K06054 HES1; hairy and enhancer of split 1
E 124045181 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 124002564 cenps; centromere protein S K11511 APITD1; centromere protein S
E 124018957 centromere protein X-like K15360 STRA13; centromere protein X
E 124026062 centromere protein X-like K15360 STRA13; centromere protein X
E 124023732 ube2t; ubiquitin-conjugating enzyme E2 T isoform X1 K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 124036418 blm; Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 124019945 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124034698 top3b; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124034549 rmi1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 124003503 fancd2; Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein
E 124035213 fanci; Fanconi anemia group I protein isoform X1 K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 124048417 breast cancer type 1 susceptibility protein homolog isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 123994837 brca2; breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 123992813 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 124037492 fan1; fanconi-associated nuclease 1 isoform X1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 123990826 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 123995151 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 123999780 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 124011253 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 124039955 telo2; telomere length regulation protein TEL2 homolog isoform X1 K11137 TELO2; telomere length regulation protein
E 123996646 usp1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 123991368 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 124009943 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 124039146 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 123989415 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 124016640 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 124033361 serine/threonine-protein phosphatase 6 catalytic subunit-like K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 124036162 serine/threonine-protein phosphatase 6 catalytic subunit-like isoform X1 K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 123994524 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 124001695 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 124013914 serine/threonine-protein phosphatase 6 regulatory subunit 2-like K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 124035965 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 123999385 serine/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 124038244 ppp6r3; serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 124005221 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 124012355 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 124024481 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 124047981 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 124002984 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 124031017 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 124032153 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 124045969 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like isoform X1 K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 123990597 E3 ubiquitin-protein ligase rnf8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 123993138 rnf168; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase rnf168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 123993176 rnf169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 123996513 herc2; E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 124013822 wrap53; telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
E 124007130 taperin-like K24164 TPRN; taperin
E 124048981 tprn; taperin K24164 TPRN; taperin
E 124013646 zinc finger CW-type PWWP domain protein 1-like isoform X1 K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
E 124048773 LOW QUALITY PROTEIN: WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 124033554 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
E 124035004 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
E 124031442 hmces; abasic site processing protein HMCES K28434 HMCES; abasic site processing protein HMCES
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 124041262 polh; DNA polymerase eta isoform X1 K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 124034494 poli; LOW QUALITY PROTEIN: DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 124034230 DNA polymerase kappa-like isoform X1 K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 124036426 DNA polymerase kappa-like isoform X1 K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 124044189 DNA repair protein REV1-like isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
D 124044543 rev1; DNA repair protein REV1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 123990676 DNA polymerase zeta catalytic subunit-like isoform X1 K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D 123995011 rev3l; DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
D 124013615 poln; LOW QUALITY PROTEIN: DNA polymerase nu K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 123993548 ubiquitin-conjugating enzyme E2 A isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 124010880 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 124044165 ubiquitin-conjugating enzyme E2 A-like isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 124045554 ubiquitin-conjugating enzyme E2 A-like isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 123999323 ubiquitin-conjugating enzyme E2 B isoform X1 K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 124013653 ubiquitin-conjugating enzyme E2 B-like K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 124003105 rad18; E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 124031245 E3 ubiquitin-protein ligase RAD18-like isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 124040246 hltf; helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 124003614 ube2v1; ubiquitin-conjugating enzyme E2 variant 1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124009118 ubiquitin-conjugating enzyme E2 variant 2 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124026745 ubiquitin-conjugating enzyme E2 variant 1-like isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124032141 ubiquitin-conjugating enzyme E2 variant 1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124041753 ube2v2; ubiquitin-conjugating enzyme E2 variant 2 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124045952 ubiquitin-conjugating enzyme E2 variant 1 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 123994407 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 124002549 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 124014117 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 124035073 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 124034195 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 124036453 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 123994487 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
D 123995087 sprtn; DNA-dependent metalloprotease SPRTN K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 123993679 acidic repeat-containing protein-like K26957 GCNA; germ cell nuclear acidic protein
D 124011408 uncharacterized protein LOC124011408 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 123993420 rad9a; cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 124036187 rad9b; cell cycle checkpoint control protein RAD9B isoform X1 K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 124039587 hus1; checkpoint protein HUS1 isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 124000498 rad1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 124036630 rad17; cell cycle checkpoint protein RAD17 isoform X1 K06662 HRAD17; cell cycle checkpoint protein
D 123996933 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 124011721 rfc2; replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 124037786 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 123995226 rfc3; LOW QUALITY PROTEIN: replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 124036588 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 124000498 rad1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 124003823 timeless; protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 124019694 TIMELESS-interacting protein-like K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 124019699 TIMELESS-interacting protein-like isoform X1 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 124012195 LOW QUALITY PROTEIN: claspin-like K25773 CLSPN; claspin
D 124043629 claspin-like isoform X1 K25773 CLSPN; claspin
C Triple T complex
D 124039955 telo2; telomere length regulation protein TEL2 homolog isoform X1 K11137 TELO2; telomere length regulation protein
D 124045855 tti1; TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 124033979 tti2; TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 124005062 bag6; large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 124012890 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 124043327 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 124034336 ubiquitin-like protein 4A-A K23388 UBL4; ubiquitin-like protein 4
D 124036287 ubiquitin-like protein 4A-B K23388 UBL4; ubiquitin-like protein 4
D 124039997 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
D 124048198 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 124010804 atr; serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 124024949 ATR-interacting protein K10905 ATRIP; ATR interacting protein
D 124004686 LOW QUALITY PROTEIN: serine-protein kinase ATM-like K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 124005493 tp53; cellular tumor antigen p53 K04451 TP53; tumor protein p53
D 124008155 cellular tumor antigen p53-like K04451 TP53; tumor protein p53
D 124014289 cellular tumor antigen p53-like isoform X1 K04451 TP53; tumor protein p53
D 124007528 chek1; serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 124034568 serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 124036029 chek2; serine/threonine-protein kinase Chk2 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 124002294 M-phase inducer phosphatase 2-like isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 124045371 cdc25b; M-phase inducer phosphatase 2 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 124007279 M-phase inducer phosphatase 1-B-like K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 123990608 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 123994871 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124001369 14-3-3 protein beta/alpha-1-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124003263 14-3-3 protein beta/alpha-1-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124008166 14-3-3 protein beta/alpha-1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124022322 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124026228 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124031666 14-3-3 protein beta/alpha-2-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124045643 14-3-3 protein beta/alpha-2 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124046306 14-3-3 protein beta/alpha-1-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 123992755 ywhag2; 14-3-3 protein gamma-2 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 124000591 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 124005799 14-3-3 protein gamma-2-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 124007390 14-3-3 protein eta-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 124014729 ywhag1; 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 124048867 ywhah; LOW QUALITY PROTEIN: 14-3-3 protein eta K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 123992982 14-3-3 protein epsilon-like isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 123998749 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 124005576 14-3-3 protein epsilon-like isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 124012747 14-3-3 protein epsilon-like K06630 YWHAE; 14-3-3 protein epsilon
D 124003629 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 124033928 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 124033942 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 124035915 nav2a; neuron navigator 2 isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 124033610 wee1-like protein kinase 1-A isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 124034548 wee2; wee1-like protein kinase 2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 124035595 wee1-like protein kinase 1-A K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 124037012 wee1; wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 124039262 wee1-like protein kinase 1-B isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 124006812 LOW QUALITY PROTEIN: period circadian protein homolog 1-like K21944 PER1; period circadian protein 1
D 124007917 period circadian protein homolog 1-like K21944 PER1; period circadian protein 1
D 124014567 per1b; period circadian protein homolog 1b isoform X1 K21944 PER1; period circadian protein 1
D 124009961 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 124041933 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 123997313 mediator of DNA damage checkpoint protein 1-like K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 123994236 plastin-3-like K17336 PLS3; plastin-3
D 123999911 plastin-3-like K17336 PLS3; plastin-3
D 124009099 plastin-3 K17336 PLS3; plastin-3
D 124037003 LOW QUALITY PROTEIN: apoptosis-enhancing nuclease-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 124039726 apoptosis-enhancing nuclease-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 124009721 serine/threonine-protein kinase PLK3-like K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 124041866 serine/threonine-protein kinase PLK3-like K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 123996839 nek1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 124002460 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 124031411 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 124046763 serine/threonine-protein kinase Nek5-like K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 123997014 nek10; serine/threonine-protein kinase Nek10 isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 124028417 serine/threonine-protein kinase Nek11-like K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 124008613 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 124011132 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 123989319 KN motif and ankyrin repeat domain-containing protein 1-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 123996467 kank4; KN motif and ankyrin repeat domain-containing protein 4 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 123997175 KN motif and ankyrin repeat domain-containing protein 3-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 123998374 KN motif and ankyrin repeat domain-containing protein 3-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 123999972 LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124009289 KN motif and ankyrin repeat domain-containing protein 1-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124015270 kank2; KN motif and ankyrin repeat domain-containing protein 2 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124027044 LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124034974 kank1a; LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 1a K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124038020 KN motif and ankyrin repeat domain-containing protein 4-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124042115 KN motif and ankyrin repeat domain-containing protein 1-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 124039183 chmp4c; LOW QUALITY PROTEIN: charged multivesicular body protein 4c K24782 CHMP4C; charged multivesicular body protein 4C
D 123992248 vps4a; vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 123996990 vacuolar protein sorting-associated protein 4B-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 124009524 vacuolar protein sorting-associated protein 4B-like isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 124037745 vacuolar protein sorting-associated protein 4B-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 124037826 vacuolar protein sorting-associated protein 4A-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 124041789 vacuolar protein sorting-associated protein 4B isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 124002003 zfyve19; abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 124002439 replication stress response regulator SDE2-like isoform X1 K25059 SDE2; replication stress response regulator SDE2
D 124002441 replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 124011839 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 124013358 primpol; DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 124039941 dclre1a; DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D 124032359 dclre1b; 5' exonuclease Apollo isoform X1 K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 123992792 exonuclease V-like K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 124011173 exonuclease V-like K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 124016054 endonuclease V-like isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 124008065 LOW QUALITY PROTEIN: DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 124008085 DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 123996636 ankle1; ankyrin repeat and LEM domain-containing protein 1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 124048737 helq; LOW QUALITY PROTEIN: helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 124034124 ercc6l2; DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 123994057 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 124001521 pre-mRNA-processing factor 19-like isoform X1 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 124012671 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 124001157 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 124046552 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 124022154 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 124002115 pleiotropic regulator 1-like K12862 PLRG1; pleiotropic regulator 1
D 124013036 pleiotropic regulator 1-like K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 124019674 nudt15; nucleotide triphosphate diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 123999502 oxidized purine nucleoside triphosphate hydrolase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 124015060 LOW QUALITY PROTEIN: oxidized purine nucleoside triphosphate hydrolase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 124033990 nudt18; 8-oxo-dGDP phosphatase NUDT18 isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 124020946 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124033519 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124033522 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123999969 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 124009694 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 123990611 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 123994878 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 124043117 rrm2b; ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 124041236 mgmt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 124042089 LOW QUALITY PROTEIN: CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 124036383 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124019462 smug1; single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 124000343 DNA-3-methyladenine glycosylase-like isoform X1 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 123997613 mutyh; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 124020653 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 124020659 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 123995620 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
E 124013788 single-stranded DNA-binding protein, mitochondrial-like K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 123995620 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
D 124013788 single-stranded DNA-binding protein, mitochondrial-like K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 124019674 nudt15; nucleotide triphosphate diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 124020946 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124033519 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124033522 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025