+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Orbus sturtevantii

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C RHO12_06185 lspA; (GenBank) signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C RHO12_11075 A24 family peptidase K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-] C RHO12_06755 prepilin peptidase K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family C RHO12_07535 hycI; (GenBank) hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family B Family C15: pyroglutamyl peptidase I family B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C RHO12_01320 guaA; (GenBank) glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] B Family C27 B Family C30 B Family C37 B Family C39 B Family C40 C RHO12_00205 NlpC/P60 family protein K13695 nlpC; probable lipoprotein NlpC B Family C44 C RHO12_07135 purF; (GenBank) amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C RHO12_09895 gltB; (GenBank) glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C RHO12_09060 glmS; (GenBank) glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C RHO12_08075 asnB; (GenBank) asparagine synthase B K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C RHO12_06925 DJ-1/PfpI family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 B Family C82 B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family # AMetallo peptidases B Family M1 C RHO12_06980 pepN; (GenBank) aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 C RHO12_06415 prlC; (GenBank) oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70] B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family B Family M7: snapalysin family B Family M8: leishmanolysin family B Family M9 B Family M10 B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family B Family M15: zinc D-Ala-D-Ala carboxypeptidase family B Family M16: pitrilysin family C RHO12_10960 ptrA; (GenBank) pitrilysin K01407 ptrA; protease III [EC:3.4.24.55] B Family M17: leucyl aminopeptidase family C RHO12_02320 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] C RHO12_08455 pepB; (GenBank) aminopeptidase PepB K07751 pepB; PepB aminopeptidase [EC:3.4.11.23] B Family M18 B Family M19: membrane dipeptidase family B Family M20 C RHO12_06545 glutamate carboxypeptidase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11] C RHO12_05035 dapE; (GenBank) succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C RHO12_02515 pepT; (GenBank) peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] C RHO12_03440 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-] C RHO12_00405 M20 aminoacylase family protein K01451 hipO; hippurate hydrolase [EC:3.5.1.32] C RHO12_03530 amidohydrolase K14665 amhX; amidohydrolase [EC:3.5.1.-] B Family M23 C RHO12_10560 mepM; (GenBank) murein DD-endopeptidase MepM K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] B Family M24 C RHO12_11585 map; (GenBank) type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C RHO12_05980 pepP; (GenBank) Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] B Family M26 B Family M27 B Family M28: aminopeptidase Y family B Family M29: aminopeptidase T family B Family M32: carboxypeptidase Taq family B Family M34: anthrax lethal factor family B Family M35: deuterolysin family B Family M36: fungalysin family B Family M38: beta-aspartyl dipeptidase family B Family M41: FtsH endopeptidase family C RHO12_10800 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C RHO12_10065 M48 family metallopeptidase K07387 K07387; metalloprotease [EC:3.4.24.-] C RHO12_10070 M48 family metalloprotease K07387 K07387; metalloprotease [EC:3.4.24.-] C RHO12_04930 M48 family metalloprotease K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family C RHO12_07215 rseP; (GenBank) RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] B Family M54 B Family M55: DppA aminopeptidase family B Family M56 B Family M67 B Family M72 B Family M73 B Family M74 B Family M80 B Family M82 B Family M85 B Family M88 B Family M90 B Family M98 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C RHO12_07080 Do family serine endopeptidase K04772 degQ; serine protease DegQ [EC:3.4.21.-] C RHO12_07085 degS; (GenBank) outer membrane-stress sensor serine endopeptidase DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family B Family S9: prolyl oligopeptidase family B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C RHO12_08065 serine hydrolase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] B Family S12: D-Ala-D-Ala carboxypeptidase B family B Family S13: D-Ala-D-Ala peptidase C family C RHO12_09325 dacB; (GenBank) serine-type D-Ala-D-Ala carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C RHO12_07190 clpP; (GenBank) ATP-dependent Clp endopeptidase proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 B Family S16: lon protease family C RHO12_07180 lon; (GenBank) endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C RHO12_11170 Lon protease family protein K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-] B Family S21: assemblin family B Family S24: LexA family C RHO12_12370 lexA; (GenBank) transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] C RHO12_01875 umuD; (GenBank) translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-] B Family S26: signal peptidase I family C RHO12_04555 lepB; (GenBank) signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 B Family S41: C-terminal processing peptidase family C RHO12_07035 prc; (GenBank) carboxy terminal-processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] B Family S45 B Family S49: protease IV family C RHO12_05085 sppA; (GenBank) signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-] C RHO12_08650 sohB; (GenBank) protease SohB K04774 sohB; serine protease SohB [EC:3.4.21.-] B Family S50 B Family S51 B Family S53 B Family S54: Rhomboid family C RHO12_02030 glpG; (GenBank) rhomboid family intramembrane serine protease GlpG K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105] B Family S55: SpoIVB peptidase family B Family S62 B Family S66 B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C RHO12_05185 hslV; (GenBank) ATP-dependent protease subunit HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] B Family T2 B Family T3: gamma-glutamyltransferase family # APeptidases of unknown catalytic type B Family U32 C RHO12_03415 yegQ; (GenBank) tRNA 5-hydroxyuridine modification protein YegQ K08303 prtC; U32 family peptidase [EC:3.4.-.-] C RHO12_04230 U32 family peptidase K24847 rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase C RHO12_10585 U32 family peptidase K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15] C RHO12_10590 peptidase U32 family protein K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15] B Family U62 C RHO12_04840 pmbA; (GenBank) metalloprotease PmbA K03592 pmbA; PmbA protein C RHO12_09185 tldD; (GenBank) metalloprotease TldD K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family C RHO12_02165 alpha-2-macroglobulin K06894 yfhM; alpha-2-macroglobulin B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 C RHO12_06025 hflC; (GenBank) protease modulator HflC K04087 hflC; modulator of FtsH protease HflC C RHO12_06030 hflK; (GenBank) FtsH protease activity modulator HflK K04088 hflK; modulator of FtsH protease HflK B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2025 #
Classification taken and modified from MEROPS