+F Repair protein KO
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DNA Repair and Recombination Proteins - Orientia tsutsugamushi Ikeda
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OTT_1542 phrB; deoxyribodipyrimidine photolyase, DNA photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OTT_1582 mpg; DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E OTT_1946 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D OTT_0534 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OTT_0966 dut; deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OTT_1542 phrB; deoxyribodipyrimidine photolyase, DNA photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OTT_0717 bacteriophage-type DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E OTT_1582 mpg; DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E OTT_1946 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E OTT_1201 xthA2; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E OTT_0179 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E OTT_1223 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E OTT_0393 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E OTT_1427 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E OTT_1940 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E OTT_1407 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E OTT_0501 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OTT_1940 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F OTT_1794 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F OTT_1793 rpoC; DNA-directed RNA polymerase beta prime chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F OTT_1068 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F OTT_0262 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E OTT_0431 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E OTT_0776 mutL; DNA mismatch repair protein MutL1 K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E OTT_1743 xseA; exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E OTT_0840 xseB; exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E OTT_1393 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E OTT_1572 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E OTT_1355 holC; DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E OTT_0244 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E OTT_1863 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E OTT_0746 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E OTT_1740 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E OTT_1940 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E OTT_0501 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E OTT_0731 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E OTT_1850 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1467 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_0318 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_0346 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1728 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_0668 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1120 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_0984 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1206 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1885 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1030 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_1240 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E OTT_0441 N6 adenine-specific DNA-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E OTT_0081 recD; exodeoxyribonuclease V alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E OTT_1040 recA; RecA protein K03553 recA; recombination protein RecA
E OTT_0635 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OTT_0634 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OTT_0923 ruvC; holliday junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E OTT_0768 priA; primosomal protein N K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E OTT_1040 recA; RecA protein K03553 recA; recombination protein RecA
E OTT_0070 radA; DNA repair protein RadA homolog K04485 radA; DNA repair protein RadA/Sms
E OTT_0951 recF; RecF protein K03629 recF; DNA replication and repair protein RecF
E OTT_1427 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E OTT_1176 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E OTT_1803 recR; recombination protein RecR K06187 recR; recombination protein RecR
E OTT_0635 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E OTT_0634 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E OTT_0923 ruvC; holliday junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E OTT_0021 putative ATP-dependent helicase/nuclease K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E OTT_1346 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F OTT_1379 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F OTT_0825 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F OTT_1325 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F OTT_0025 hupA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F OTT_1427 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F OTT_1176 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F OTT_1803 recR; recombination protein RecR K06187 recR; recombination protein RecR
F OTT_1940 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F OTT_1407 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D OTT_1040 recA; RecA protein K03553 recA; recombination protein RecA
D OTT_0731 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D OTT_0534 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OTT_0966 dut; deoxyuridine 5-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OTT_1456 nrdA; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OTT_1457 nrdB; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024