+F Repair protein KO
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DNA Repair and Recombination Proteins - Paenibacillus sp. FSL R5-0345
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E R50345_22010 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E R50345_02905 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E R50345_20445 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E R50345_12460 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E R50345_29175 ATP-dependent helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D R50345_01915 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_17395 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_14070 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_14570 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_15815 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_04260 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_13890 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_18570 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D R50345_26105 cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D R50345_18280 AraC family transcriptional regulator K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D R50345_18275 cysteine methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E R50345_22010 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E R50345_04430 DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E R50345_07135 DNA-3-methyladenine glycosidase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E R50345_02905 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E R50345_23505 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E R50345_09705 5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E R50345_17005 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E R50345_20445 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E R50345_13075 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E R50345_14870 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E R50345_06205 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E R50345_17000 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E R50345_23895 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E R50345_28135 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E R50345_09700 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E R50345_11355 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E R50345_28275 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E R50345_28280 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E R50345_05585 UvrABC system subunit C K03703 uvrC; excinuclease ABC subunit C
E R50345_25605 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E R50345_15955 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_30250 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_23820 helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_12785 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_28140 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_01535 ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_09700 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E R50345_28135 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F R50345_27955 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F R50345_27950 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F R50345_27770 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F R50345_00615 DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta
F R50345_12550 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F R50345_00275 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E R50345_17155 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E R50345_08340 recombination and DNA strand exchange inhibitor protein K07456 mutS2; DNA mismatch repair protein MutS2
E R50345_30705 DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E R50345_17150 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E R50345_21540 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E R50345_21535 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E R50345_09575 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E R50345_18640 polC; DNA polymerase III PolC K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E R50345_00015 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E R50345_11945 hypothetical protein K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E R50345_23640 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E R50345_00155 ATPase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E R50345_10825 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E R50345_07125 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E R50345_00670 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E R50345_28135 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E R50345_15955 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_30250 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_23820 helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_12785 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_28140 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_01535 ATP-dependent DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E R50345_30715 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E R50345_18470 recombinase RecA K03553 recA; recombination protein RecA
E R50345_23965 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E R50345_23960 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E R50345_23970 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E R50345_12560 primosomal protein DnaI K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E R50345_08795 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E R50345_23405 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E R50345_23410 nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E R50345_18470 recombinase RecA K03553 recA; recombination protein RecA
E R50345_28055 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E R50345_00025 recombinase RecF K03629 recF; DNA replication and repair protein RecF
E R50345_08740 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E R50345_12625 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E R50345_23895 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E R50345_23320 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E R50345_00680 recombinase RecR K06187 recR; recombination protein RecR
E R50345_21505 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E R50345_23965 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E R50345_23960 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E R50345_23970 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E R50345_23415 ATP-dependent helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E R50345_23420 ATP-dependent helicase K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E R50345_08795 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E R50345_23405 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E R50345_23410 nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E R50345_04805 DNA repair protein K10979 ku; DNA end-binding protein Ku
E R50345_04800 DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E R50345_04765 DNA polymerase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F R50345_00045 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F R50345_00035 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F R50345_18890 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F R50345_20810 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F R50345_00305 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F R50345_05895 recombinase RecT K07455 recT; recombination protein RecT
F R50345_23895 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F R50345_23320 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F R50345_00680 recombinase RecR K06187 recR; recombination protein RecR
F R50345_28135 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F R50345_06675 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F R50345_11355 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F R50345_28275 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F R50345_28280 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D R50345_10845 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D R50345_12120 polYB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D R50345_18470 recombinase RecA K03553 recA; recombination protein RecA
D R50345_17050 XRE family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D R50345_21505 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D R50345_30715 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50345_18465 RecX family transcriptional regulator K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D R50345_20575 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D R50345_10175 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D R50345_07455 hypothetical protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D R50345_16340 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D R50345_01915 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_17395 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_14070 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_14570 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_15815 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_04260 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_13890 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50345_18570 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D R50345_02305 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50345_11155 ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50345_07195 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50345_02300 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D R50345_07190 ribonucleotide-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D R50345_18605 exopolyphosphatase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024