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Transfer RNA Biogenesis - Pseudomonas aeruginosa PAO581
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
C CCA adding factors
D M801_598 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D M801_4599 tRNA-splicing ligase RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D M801_3112 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D M801_990 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D M801_4575 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D M801_3983 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D M801_3470 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D M801_1841 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D M801_5089 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D M801_3689 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D M801_997 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D M801_931 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D M801_2693 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D M801_2558 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D M801_1842 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D M801_3826 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D M801_3793 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D M801_2689 pheS; phenylalanine--tRNA ligase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D M801_2688 pheT; phenylalanine--tRNA ligase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D M801_682 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D M801_4136 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D M801_4449 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D M801_5117 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D M801_2170 threonyl and Alanyl tRNA synthetase second additional domain protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D M801_3276 hit-like protein involved in cell-cycle regulation K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D M801_670 HIT domain protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D M801_1345 HIT domain protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D M801_392 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D M801_3373 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D M801_3088 truA; tRNA pseudouridine(38-40) synthase K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D M801_4771 truB; tRNA pseudouridine(55) synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D M801_3615 tRNA pseudouridine synthase, TruD family protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D M801_2125 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D M801_3805 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D M801_22 telomere recombination family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D M801_4982 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D M801_5619 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D M801_5617 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D M801_1686 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D M801_5217 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D M801_5621 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D M801_3516 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D M801_5379 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D M801_1333 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D M801_598 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D M801_4599 tRNA-splicing ligase RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D M801_2828 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D M801_60 RNA 2'-phosphotransferase, Tpt1 / KptA family protein K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D M801_4611 ccmA; heme ABC exporter, ATP-binding protein CcmA K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D M801_3983 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D M801_990 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D M801_682 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D M801_4136 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D M801_4449 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D M801_2693 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D M801_4575 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D M801_3689 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D M801_931 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D M801_3826 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D M801_3470 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D M801_2558 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D M801_997 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D M801_9 glyQ; glycine--tRNA ligase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D M801_8 glyS; glycine--tRNA ligase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D M801_1842 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D M801_3112 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D M801_1841 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D M801_5089 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D M801_2689 pheS; phenylalanine--tRNA ligase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D M801_2688 pheT; phenylalanine--tRNA ligase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D M801_3793 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D M801_4752 gluQ; glutamyl-queuosine tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D M801_5117 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D M801_3569 aminoacyl-tRNA editing domain protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D M801_1897 aminoacyl-tRNA editing domain protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
D M801_2170 threonyl and Alanyl tRNA synthetase second additional domain protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D M801_3757 cytidine and deoxycytidylate deaminase zinc-binding region family protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D M801_2760 dusA; tRNA dihydrouridine synthase A family protein K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D M801_4887 TIM-barrel, nifR3 family protein K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D M801_3103 dihydrouridine synthase family protein K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D M801_3976 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D M801_2097 methyltransferase domain protein K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D M801_801 cmoA; tRNA (cmo5U34)-methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D M801_800 cmoB; tRNA (mo5U34)-methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D M801_4821 methyltransferase domain protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D M801_4748 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D M801_392 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D M801_3732 trmD; tRNA (guanine(37)-N(1))-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D M801_5619 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D M801_3808 trmJ; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D M801_5165 trmL; tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D M801_3373 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D M801_3088 truA; tRNA pseudouridine(38-40) synthase K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D M801_4771 truB; tRNA pseudouridine(55) synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D M801_3615 tRNA pseudouridine synthase, TruD family protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D M801_2106 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D M801_3223 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D M801_2572 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D M801_1230 PP-loop family protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D M801_1607 tusA; sulfurtransferase tusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D M801_1039 sulfurtransferase TusA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D M801_2553 dsrH; sulfur relay protein TusB/DsrH K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D M801_2552 tusC; sulfur relay protein TusC/DsrF K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D M801_2551 putative sulfurtransferase dsrE K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D M801_2554 tusE; sulfur relay, TusE/DsrC/DsvC family protein K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D M801_3803 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D M801_2125 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D M801_3805 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D M801_783 aminomethyltransferase folate-binding domain protein K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D M801_5617 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D M801_4982 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D M801_1837 tRNA-(Ms(2)io(6)a)-hydroxylase, putative K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D M801_3444 mnmC; MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D M801_3815 queA; tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D M801_1010 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D M801_2613 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D M801_1009 radical SAM superfamily protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D M801_2771 queF; queuine synthase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D M801_4987 queG; epoxyqueuosine reductase K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D M801_1686 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D M801_1688 selU; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D M801_3814 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D M801_5156 thiI; tRNA sulfurtransferase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D M801_3627 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D M801_3674 yeaZ; tRNA threonylcarbamoyl adenosine modification protein YeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D M801_22 telomere recombination family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D M801_595 tRNA threonylcarbamoyl adenosine modification protein YgjD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D M801_4985 tRNA threonylcarbamoyl adenosine modification protein YjeE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D M801_1203 thiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C M801_4972 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C M801_4769 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024