+F Repair protein KO
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DNA Repair and Recombination Proteins - Pseudomonas aeruginosa PAO581
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D M801_1028 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D M801_4680 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E M801_774 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E M801_4005 methylpurine-DNA glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E M801_5187 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E M801_3483 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E M801_1923 DEAD_2 family protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D M801_3156 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_2730 nudt1; nudix hydrolase 1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_4410 mutator mutT family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_4951 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_3458 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_5366 dut; dUTP diphosphatase family protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D M801_1028 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D M801_2182 methylated-DNA-[]-cysteine S-methyltransferase family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D M801_3584 methylated-DNA-[]-cysteine S-methyltransferase family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D M801_4680 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E M801_774 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E M801_1732 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E M801_4005 methylpurine-DNA glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E M801_5187 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E M801_10 tag; DNA-3-methyladenine glycosylase I family protein K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E M801_366 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E M801_3483 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E M801_5377 exodeoxyribonuclease III family protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E M801_2482 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E M801_4170 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E M801_3713 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E M801_1570 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E M801_5545 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E M801_4232 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E M801_3116 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E M801_2530 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E M801_5496 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E M801_1996 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E M801_5545 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E M801_1570 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F M801_4268 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F M801_4267 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F M801_4236 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F M801_5382 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F M801_2973 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E M801_3609 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E M801_4983 mutL; DNA mismatch repair MutL family protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E M801_4324 hypothetical protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E M801_3767 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E M801_4037 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E M801_3629 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E M801_2 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E M801_3824 DNA polymerase III chi subunit, HolC family protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E M801_3985 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E M801_2931 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E M801_3209 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M801_1870 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M801_1573 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E M801_1570 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E M801_5496 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E M801_1996 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E M801_4230 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E M801_4291 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E M801_4292 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E M801_4290 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E M801_3606 recA; protein RecA K03553 recA; recombination protein RecA
E M801_1000 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E M801_1001 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E M801_999 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E M801_5088 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E M801_2675 tyrosine kinase family protein K04067 priC; primosomal replication protein N''
E M801_4324 hypothetical protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E M801_4289 AAA domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E M801_4288 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E M801_3606 recA; protein RecA K03553 recA; recombination protein RecA
E M801_4626 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E M801_3 recF; DNA replication and repair RecF family protein K03629 recF; DNA replication and repair protein RecF
E M801_5390 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E M801_3713 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E M801_798 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E M801_1575 recR; recombination protein RecR K06187 recR; recombination protein RecR
E M801_4793 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E M801_3244 rdgC; recombination-associated protein rdgC K03554 rdgC; recombination associated protein RdgC
E M801_1000 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E M801_1001 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E M801_999 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E M801_4289 AAA domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E M801_4288 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E M801_4315 ftsK/SpoIIIE family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E M801_2219 Ku protein K10979 ku; DNA end-binding protein Ku
E M801_2204 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F M801_3144 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F M801_4 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F M801_2982 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F M801_2315 eukaryotic DNA topoisomerase I, catalytic core family protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F M801_5393 hupB; DNA-binding protein HU-beta K05787 hupA; DNA-binding protein HU-alpha
F M801_3935 hupA; DNA-binding protein HU 1 K03530 hupB; DNA-binding protein HU-beta
F M801_1857 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F M801_3713 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F M801_798 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F M801_1575 recR; recombination protein RecR K06187 recR; recombination protein RecR
F M801_1570 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F M801_4888 bacterial regulatory, Fis family protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F M801_2687 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F M801_3137 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F M801_4324 hypothetical protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F M801_3328 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F M801_4232 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F M801_3116 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D M801_955 hypothetical protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D M801_3606 recA; protein RecA K03553 recA; recombination protein RecA
D M801_2978 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D M801_4793 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D M801_1944 DNA polymerase family B, exonuclease domain protein K02336 polB; DNA polymerase II [EC:2.7.7.7]
D M801_690 hypothetical protein K14160 imuA; protein ImuA
D M801_689 hypothetical protein K14161 imuB; protein ImuB
D M801_688 dnaE; DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D M801_4230 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D M801_3605 recX family protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D M801_5341 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D M801_1081 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D M801_3253 DEAD/H associated family protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D M801_3156 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_2730 nudt1; nudix hydrolase 1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_4410 mutator mutT family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_4951 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_3458 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D M801_5366 dut; dUTP diphosphatase family protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D M801_1194 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D M801_5549 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D M801_1193 ribonucleotide reductase, small chain family protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024