+F Repair protein KO
#
DNA Repair and Recombination Proteins - Podospora bellae-mahoneyi
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D QC761_604880 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QC761_0000080 PHR1_1; DNA photolyase phr1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D QC761_0029550 PHR1_2; DNA photolyase phr1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E QC761_108860 UNG1; uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QC761_102290 thp1; uracil DNA N-glycosylase Thp1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E QC761_117800 OGG1; 8-oxoguanine glycosylase ogg1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E QC761_110510 APN1; DNA-(apurinic or apyrimidinic site) lyase K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E QC761_120580 APN2; DNA-(apurinic or apyrimidinic site) lyase 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F QC761_210460 POL3; DNA-directed DNA polymerase delta K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F QC761_205850 cdc1; DNA polymerase delta small subunit Cdc1 K02328 POLD2; DNA polymerase delta subunit 2
F QC761_601245 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
F QC761_305790 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F QC761_503400 POL2; DNA polymerase epsilon catalytic subunit K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F QC761_200540 DPB2; DNA-directed DNA polymerase epsilon, subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E QC761_110930 POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E QC761_509590 FEN1; Elongation of fatty acids protein 2 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E QC761_710060 cdc17; ATP-dependent DNA ligase Cdc17 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E QC761_122720 uncharacterized protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E QC761_608770 HNT3; aprataxin-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E QC761_502490 pnk1; DNA kinase/phosphatase Pnk1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E QC761_000940 hypothetical protein K28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F QC761_409400 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F QC761_600730 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F QC761_707730 RAD23; UV excision repair protein rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F QC761_708750 HRT1; RING-box protein hrt1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F QC761_705460 hypothetical protein K10609 CUL4; cullin 4
F QC761_600250 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F QC761_211110 RAD7; UV-damaged DNA-binding protein rad7 K15082 RAD7; DNA repair protein RAD7
F QC761_211100 RAD16; DNA repair protein rad16 K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F QC761_102650 RPO21; DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F QC761_401700 RPB2; DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F QC761_309390 rpb3; RNA polymerase II subunit 3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F QC761_114130 uncharacterized protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F QC761_303870 RPB5; DNA-directed RNA polymerases II 24 kDa polypeptide (RNA polymerase II subunit 5) K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F QC761_709740 RPO26; subunit common to RNA polymerases I, II, and III K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F QC761_116720 RPB7; DNA-directed RNA polymerase II subunit K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F QC761_602130 RPB8; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F QC761_703840 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F QC761_102560 RPB10; DNA-directed RNA polymerase II subunit L K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F QC761_205823 RPB11; DNA-directed RNA polymerase II core subunit K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F QC761_607080 RPC10; DNA-directed RNA polymerase core subunit rpc10 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F QC761_708750 HRT1; RING-box protein hrt1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F QC761_705460 hypothetical protein K10609 CUL4; cullin 4
F QC761_600250 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F QC761_711430 rhp26; DNA repair protein rhp26 K10841 ERCC6; DNA excision repair protein ERCC-6
F QC761_205280 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E QC761_709980 SSL2; DNA repair helicase RAD25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E QC761_605400 RAD3; TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E QC761_605570 TFB1; RNA polymerase II transcription factor B subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E QC761_308890 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E QC761_307420 TFB4; RNA polymerase II transcription factor B subunit 4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E QC761_404070 TFB2; RNA polymerase II transcription factor B 52 kDa subunit K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E QC761_202040 TFB5; TFIIH complex subunit tfb5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E QC761_205940 KIN28; TFIIH complex serine/threonine-protein kinase subunit kin28 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E QC761_208410 hypothetical protein K06634 CCNH; cyclin H
E QC761_111220 TFB3; TFIIH/NER complex subunit K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E QC761_201130 RFA1; Replication factor A protein 1 K07466 RFA1; replication factor A1
E QC761_603040 ssb2; Replication factor A protein 2 K10739 RFA2; replication factor A2
E QC761_205210 hypothetical protein K10740 RPA3; replication factor A3
D Other NER factors
E QC761_611780 RAD14; DNA repair protein rad14 K10847 XPA; DNA-repair protein complementing XP-A cells
E QC761_408130 RAD10; ssDNA endonuclease and repair protein rad10 K10849 ERCC1; DNA excision repair protein ERCC-1
E QC761_119350 rad16; DNA repair protein RAD16 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E QC761_109750 RAD2; DNA repair protein rad2 K10846 ERCC5; DNA excision repair protein ERCC-5
E QC761_710060 cdc17; ATP-dependent DNA ligase Cdc17 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E QC761_116800 uncharacterized protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E QC761_605580 CIA1; Cytosolic iron-sulfur protein assembly protein K24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1
E QC761_108970 uncharacterized protein K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E QC761_104610 uncharacterized protein K03869 CUL3; cullin 3
E QC761_604040 ELC1; elongin C K03872 ELOC; elongin-C
E QC761_107000 uncharacterized protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E QC761_509410 msh2; MSH2 protein K08735 MSH2; DNA mismatch repair protein MSH2
E QC761_108810 MSH3; Mismatch repair protein msh3 K08736 MSH3; DNA mismatch repair protein MSH3
E QC761_503880 MSH6; DNA mismatch repair protein msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E QC761_602940 mlh1; DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E QC761_601450 PMS1; ATP-binding mismatch repair protein K10858 PMS2; DNA mismatch repair protein PMS2
E QC761_309800 MLH3; DNA mismatch repair protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E QC761_210460 POL3; DNA-directed DNA polymerase delta K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E QC761_205850 cdc1; DNA polymerase delta small subunit Cdc1 K02328 POLD2; DNA polymerase delta subunit 2
E QC761_601245 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E QC761_305790 hypothetical protein K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E QC761_201130 RFA1; Replication factor A protein 1 K07466 RFA1; replication factor A1
E QC761_603040 ssb2; Replication factor A protein 2 K10739 RFA2; replication factor A2
E QC761_205210 hypothetical protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E QC761_309070 rfc1; DNA replication factor C complex subunit Rfc1 K10754 RFC1; replication factor C subunit 1
E QC761_113260 RFC2; Subunit of heteropentameric Replication factor C (RF-C) K10755 RFC2_4; replication factor C subunit 2/4
E QC761_202820 RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E QC761_307820 RFC5; Replication factor C (RF-C) subunit K10756 RFC3_5; replication factor C subunit 3/5
E QC761_311490 RFC3; Subunit of heteropentameric Replication factor C (RF-C) K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E QC761_110930 POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E QC761_508570 EXO1; Rad2 nuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E QC761_710060 cdc17; ATP-dependent DNA ligase Cdc17 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E QC761_506590 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E QC761_611830 MRE11; meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E QC761_101880 RAD50; DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E QC761_611830 MRE11; meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E QC761_101880 RAD50; DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E QC761_113570 rhp51; RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E QC761_113570 rhp51; RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
E QC761_307770 rhp57; DNA repair protein rhp57 K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E QC761_212450 RAD52; DNA repair protein rad52 K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E QC761_506320 RAD54; DNA-dependent ATPase protein rad54 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E QC761_110750 SGS1; ATP-dependent DNA helicase sgs1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E QC761_110750 SGS1; ATP-dependent DNA helicase sgs1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E QC761_709280 TOP3; DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E QC761_201130 RFA1; Replication factor A protein 1 K07466 RFA1; replication factor A1
E QC761_603040 ssb2; Replication factor A protein 2 K10739 RFA2; replication factor A2
E QC761_205210 hypothetical protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E QC761_605820 PSY2; Platinum sensitivity protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E QC761_119340 SMC5; Structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E QC761_505760 smc6; Structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E QC761_123620 uncharacterized protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E QC761_406970 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E QC761_120020 uncharacterized protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E QC761_307400 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E QC761_610600 SEM1; 26S proteasome complex subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E QC761_108940 uncharacterized protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E QC761_206950 SLX1; Slx4p interacting protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E QC761_604550 hypothetical protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E QC761_0057770 EAF3_2; Esa1p-associated factor K11339 MORF4L1; mortality factor 4-like protein 1
E QC761_505570 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E QC761_110010 uncharacterized protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E QC761_112430 MPH1; 3'-5' DNA helicase K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E QC761_606180 ATP-dependent DNA helicase II subunit 1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E QC761_709250 YKU80; ATP-dependent DNA helicase yku80 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E QC761_611830 MRE11; meiotic recombination K10865 MRE11; double-strand break repair protein MRE11
E QC761_101880 RAD50; DNA repair protein rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E QC761_706470 LIG4; DNA ligase (ATP) K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E QC761_109870 uncharacterized protein K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E QC761_202540 hypothetical protein K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E QC761_608770 HNT3; aprataxin-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E QC761_407530 hypothetical protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E QC761_0056810 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E QC761_209255 MHF1; MHF histone-fold complex component K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E QC761_110750 SGS1; ATP-dependent DNA helicase sgs1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E QC761_709280 TOP3; DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E QC761_117830 uncharacterized protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E QC761_113570 rhp51; RecA recombinase Rhp51 K04482 RAD51; DNA repair protein RAD51
E QC761_108590 TEL2; telomere binding protein K11137 TELO2; telomere length regulation protein
E QC761_305430 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E QC761_600180 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E QC761_709580 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
E QC761_506590 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D QC761_120790 RAD30; DNA-directed DNA polymerase eta rad30 K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D QC761_308130 hypothetical protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D QC761_505250 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D QC761_110240 REV1; deoxycytidyl transferase K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D QC761_120650 REV3; DNA polymerase zeta K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D QC761_601580 UBC2; Ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D QC761_124110 RAD18; E3 ubiquitin-protein ligase rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D QC761_701570 RAD5; DNA helicase rad5 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D QC761_303300 hypothetical protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D QC761_405930 MMS2; E2 ubiquitin-conjugating protein mms2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D QC761_120060 uncharacterized protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D QC761_110930 POL30; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D QC761_508400 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D QC761_706150 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D QC761_209580 hus1; Checkpoint protein hus1 K10903 HUS1; HUS1 checkpoint protein
D QC761_103480 rad1_2; checkpoint clamp complex protein Rad1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D QC761_118620 rad17; RFC checkpoint protein Rad17 K06662 HRAD17; cell cycle checkpoint protein
D QC761_113260 RFC2; Subunit of heteropentameric Replication factor C (RF-C) K10755 RFC2_4; replication factor C subunit 2/4
D QC761_202820 RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D QC761_307820 RFC5; Replication factor C (RF-C) subunit K10756 RFC3_5; replication factor C subunit 3/5
D QC761_311490 RFC3; Subunit of heteropentameric Replication factor C (RF-C) K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D QC761_103480 rad1_2; checkpoint clamp complex protein Rad1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D QC761_204970 TOF1; Topoisomerase 1-associated factor 1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D QC761_122020 CSM3; chromosome segregation in meiosis-related protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D QC761_212800 hypothetical protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D QC761_108590 TEL2; telomere binding protein K11137 TELO2; telomere length regulation protein
D QC761_705120 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D QC761_605730 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
D QC761_210470 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D QC761_114870 MEC1; serine/threonine-protein kinase M1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D QC761_707600 TEL1; Serine/threonine-protein kinase tel1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D QC761_103950 chk1; Chk1 protein kinase K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D QC761_107860 DUN1; serine/threonine protein kinase K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D QC761_104650 MIH1; m-phase inducer phosphatase K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D QC761_107100 uncharacterized protein K06630 YWHAE; 14-3-3 protein epsilon
D QC761_107890 BMH1; 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D QC761_212790 SWE1; mitosis inhibitor protein kinase swe1 K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D QC761_705690 FKH2; transcription factor K24664 FKH; forkhead protein FKH
D QC761_512960 VPS4; Vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D QC761_308960 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D QC761_104660 POL5; DNA-directed DNA polymerase K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D QC761_117880 pso2; DNA cross-link repair protein PSO2/SNM1 K15340 DCLRE1A; DNA cross-link repair 1A protein
D QC761_606520 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D QC761_116910 uncharacterized protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D QC761_212620 hypothetical protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D QC761_700710 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D QC761_123660 CEF1; Pre-mRNA-splicing factor cef1 K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D QC761_201910 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D QC761_118510 PRP46; pre-mRNA-splicing factor prp46 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D QC761_0041030 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QC761_101350 uncharacterized protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QC761_110900 DUT1; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D QC761_604460 RNR1; ribonucleotide-diphosphate reductase subunit rnr1 K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D QC761_711090 RNR2; Ribonucleotide-diphosphate reductase (RNR), small subunit K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D QC761_604880 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D QC761_0000080 PHR1_1; DNA photolyase phr1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D QC761_0029550 PHR1_2; DNA photolyase phr1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E QC761_108860 UNG1; uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E QC761_212990 MAG1; 3-methyladenine DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E QC761_406840 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E QC761_407360 srs2; ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E QC761_407360 srs2; ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D QC761_0041030 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QC761_101350 uncharacterized protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D QC761_110900 DUT1; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 10, 2025