+E Ubiquitin system KO
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Ubiquitin System - Prionailurus bengalensis (leopard cat)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 122481671 LOW QUALITY PROTEIN: ubiquitin-like K04551 UBB; ubiquitin B
C 122484999 UBB; polyubiquitin-B K04551 UBB; ubiquitin B
C 122470130 UBC; polyubiquitin-C isoform X1 K08770 UBC; ubiquitin C
C 122487115 UBA52; ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 122480265 ubiquitin-40S ribosomal protein S27a-like K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 122496855 RPS27A; ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 122490234 UBD; LOW QUALITY PROTEIN: ubiquitin D K12157 UBD; ubiquitin D
C 122468941 NEDD8; NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 122484000 FAU; ubiquitin-like protein fubi and ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C 122479766 ISG15; ubiquitin-like protein ISG15 K12159 ISG15; ubiquitin cross-reactive protein
C 122468070 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
C 122478027 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 122478971 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 122481362 small ubiquitin-related modifier 1-like K12160 SUMO; small ubiquitin-related modifier
C 122481653 SUMO1; small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 122485890 SUMO2; small ubiquitin-related modifier 2 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 122491087 SUMO3; small ubiquitin-related modifier 3 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 122473907 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 122484859 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 122494479 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 isoform X1 K08341 GABARAP; GABA(A) receptor-associated protein
C 122473641 ATG12; ubiquitin-like protein ATG12 isoform X1 K08336 ATG12; ubiquitin-like protein ATG12
C 122481718 UFM1; ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 122481066 UBL3; ubiquitin-like protein 3 K28515 UBL3; membrane-anchored ubiquitin-fold protein
C 122492981 ZFAND4; AN1-type zinc finger protein 4 isoform X1 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 122476786 UBA1; ubiquitin-like modifier-activating enzyme 1 isoform X1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 122493880 SAE1; SUMO-activating enzyme subunit 1 isoform X1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 122494121 UBA2; SUMO-activating enzyme subunit 2 isoform X1 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 122487420 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X1 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 122494347 NAE1; NEDD8-activating enzyme E1 regulatory subunit isoform X1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 122467269 MOCS3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 122491988 UBA5; ubiquitin-like modifier-activating enzyme 5 isoform X1 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 122488721 UBA7; ubiquitin-like modifier-activating enzyme 7 isoform X1 K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
C 122478846 UBA6; ubiquitin-like modifier-activating enzyme 6 isoform X1 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 122487511 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 122477913 UBE2A; ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 122487481 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 122467342 UBE2C; ubiquitin-conjugating enzyme E2 C isoform X1 K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 122477961 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 122480132 UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 122492772 UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 122481524 UBE2E3; LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 E3 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 122492046 ubiquitin-conjugating enzyme E2 E2 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 122492050 UBE2E1; ubiquitin-conjugating enzyme E2 E1 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 122484771 UBE2G1; ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 122491085 UBE2G2; ubiquitin-conjugating enzyme E2 G2 isoform X1 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 122488262 UBE2H; ubiquitin-conjugating enzyme E2 H isoform X1 K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 122489758 UBE2J1; ubiquitin-conjugating enzyme E2 J1 isoform X1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 122479780 UBE2J2; ubiquitin-conjugating enzyme E2 J2 isoform X1 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 122466886 UBE2K; ubiquitin-conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 122470512 UBE2L3; ubiquitin-conjugating enzyme E2 L3 isoform X1 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 122483784 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 122472485 UBE2N; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 122494060 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 122486121 UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 122468370 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 122476522 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 122495596 UBE2QL1; ubiquitin-conjugating enzyme E2Q-like protein 1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 122474894 UBE2R2; ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 122486602 CDC34; ubiquitin-conjugating enzyme E2 R1 isoform X1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 122493722 UBE2S; ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 122475803 UBE2T; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 122480598 UBE2U; LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 U K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 122495494 UBE2W; ubiquitin-conjugating enzyme E2 W isoform X1 K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 122485406 UBE2Z; ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 122466918 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 122471874 UBE2I; SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 122481965 UBE2F; NEDD8-conjugating enzyme UBE2F isoform X1 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 122494671 UBE2M; NEDD8-conjugating enzyme Ubc12 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 122483784 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 122491438 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 122490552 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 122476138 UFC1; ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 122468351 UBE3A; ubiquitin-protein ligase E3A isoform X1 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 122470348 UBE3B; ubiquitin-protein ligase E3B isoform X1 K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 122488566 UBE3C; ubiquitin-protein ligase E3C isoform X1 K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 122490361 UBE3D; E3 ubiquitin-protein ligase E3D isoform X1 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 122471281 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 122485782 SMURF2; E3 ubiquitin-protein ligase SMURF2 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 122497546 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 122495559 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 122494404 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1 K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
C 122481874 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 122468607 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 122470800 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 122477348 HUWE1; E3 ubiquitin-protein ligase HUWE1 isoform X1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 122469327 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 122495680 UBR5; E3 ubiquitin-protein ligase UBR5 isoform X1 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 122467729 G2E3; G2/M phase-specific E3 ubiquitin-protein ligase isoform X1 K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 122468539 HERC1; probable E3 ubiquitin-protein ligase HERC1 isoform X1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 122468361 HERC2; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 122478663 HERC3; probable E3 ubiquitin-protein ligase HERC3 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 122492809 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X1 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 122489803 HACE1; E3 ubiquitin-protein ligase HACE1 isoform X1 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 122487696 HECW1; E3 ubiquitin-protein ligase HECW1 isoform X1 K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]
C 122481599 HECW2; E3 ubiquitin-protein ligase HECW2 isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 122467734 HECTD1; E3 ubiquitin-protein ligase HECTD1 isoform X1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 122493017 HECTD2; probable E3 ubiquitin-protein ligase HECTD2 isoform X1 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 122480417 HECTD3; E3 ubiquitin-protein ligase HECTD3 isoform X1 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 122470237 HECTD4; probable E3 ubiquitin-protein ligase HECTD4 isoform X1 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 122483879 NDFIP2; NEDD4 family-interacting protein 2 K25839 NDFIP; NEDD4 family-interacting protein
D 122488423 NDFIP1; NEDD4 family-interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
D 122486388 N4BP3; NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
D 122471681 CE3H16orf72; UPF0472 protein C16orf72 homolog K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
D 122477925 UPF0472 protein C16orf72 K27700 HAPSTR2; HUWE1-associated protein modifying stress responses 2
B U-box type E3
C 122483029 UBE4A; ubiquitin conjugation factor E4 A isoform X1 K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 122482072 UBE4B; ubiquitin conjugation factor E4 B isoform X1 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 122471911 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 122470515 PPIL2; RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 122483839 PRPF19; pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 122471543 RBBP6; E3 ubiquitin-protein ligase RBBP6 isoform X1 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 122496500 UBOX5; RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D 122471435 RNF40; E3 ubiquitin-protein ligase BRE1B K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
D 122475006 RNF20; E3 ubiquitin-protein ligase BRE1A K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 122483059 CBL; E3 ubiquitin-protein ligase CBL isoform X1 K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 122491397 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
D 122493912 CBLC; E3 ubiquitin-protein ligase CBL-C K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 122477369 E3 ubiquitin-protein ligase SIAH1-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 122494172 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 122491852 SIAH2; E3 ubiquitin-protein ligase SIAH2 K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 122478873 LNX1; E3 ubiquitin-protein ligase LNX isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 122480926 LNX2; ligand of Numb protein X 2 isoform X1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 122473151 PDZRN4; PDZ domain-containing RING finger protein 4 isoform X1 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
D 122487443 PDZRN3; E3 ubiquitin-protein ligase PDZRN3 isoform X1 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 122474866 MARCHF1; E3 ubiquitin-protein ligase MARCHF1 isoform X1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 122492983 MARCHF8; E3 ubiquitin-protein ligase MARCHF8 isoform X1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 122486814 MARCHF2; E3 ubiquitin-protein ligase MARCHF2 isoform X1 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 122486934 MARCHF3; E3 ubiquitin-protein ligase MARCHF3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 122473829 MARCHF9; E3 ubiquitin-protein ligase MARCHF9 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 122481745 MARCHF4; E3 ubiquitin-protein ligase MARCHF4 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 122495162 MARCHF11; E3 ubiquitin-protein ligase MARCHF11 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 122493025 MARCHF5; E3 ubiquitin-protein ligase MARCHF5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 122495386 MARCHF6; E3 ubiquitin-protein ligase MARCHF6 isoform X1 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 122481370 MARCHF7; E3 ubiquitin-protein ligase MARCHF7 isoform X1 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
D 122485751 MARCHF10; LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase MARCHF10 K10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 122474007 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 122476236 MDM4; protein Mdm4 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 122475072 NFX1; transcriptional repressor NF-X1 isoform X1 K12236 NFX1; transcriptional repressor NF-X1
D 122478915 NFXL1; NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 122469134 PELI2; E3 ubiquitin-protein ligase pellino homolog 2 K11964 PELI; pellino [EC:2.3.2.27]
D 122484020 PELI3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X1 K11964 PELI; pellino [EC:2.3.2.27]
D 122496907 PELI1; E3 ubiquitin-protein ligase pellino homolog 1 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 122479821 PEX10; peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 122485235 PEX12; peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 122495508 PEX2; peroxisome biogenesis factor 2 isoform X1 K06664 PEX2; peroxin-2
C RBR proteins
D 122490161 PRKN; E3 ubiquitin-protein ligase parkin isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 122487870 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 isoform X1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 122468463 ARIH1; E3 ubiquitin-protein ligase ARIH1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 122488698 ARIH2; E3 ubiquitin-protein ligase ARIH2 isoform X1 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 122496433 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 122484883 RNF14; E3 ubiquitin-protein ligase RNF14 isoform X1 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 122495665 RNF19A; E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 122482117 RNF19B; E3 ubiquitin-protein ligase RNF19B isoform X1 K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 122468926 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 122470198 RNF34; E3 ubiquitin-protein ligase RNF34 isoform X1 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 122485229 RFFL; E3 ubiquitin-protein ligase rififylin isoform X1 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 122489192 RNF144B; E3 ubiquitin-protein ligase RNF144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 122497497 RNF144A; E3 ubiquitin-protein ligase RNF144A isoform X1 K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 122476876 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168-like K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 122491565 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 122483339 RNF169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 122474350 RNF183; E3 ubiquitin-protein ligase RNF183 K22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]
D 122471247 RNF216; E3 ubiquitin-protein ligase RNF216 isoform X1 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 122489947 RNF217; probable E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 122474992 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 122476367 TRAF5; TNF receptor-associated factor 5 isoform X1 K09849 TRAF5; TNF receptor-associated factor 5
D 122483712 TRAF6; TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 122471818 TRAF7; E3 ubiquitin-protein ligase TRAF7 isoform X1 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 122477771 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X1 K10647 TRIM1; midline 2 [EC:2.3.2.27]
D 122475318 TRIM2; tripartite motif-containing protein 2 isoform X1 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 122483496 TRIM3; tripartite motif-containing protein 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 122471977 TRIM4; E3 ubiquitin-protein ligase TRIM4 K11998 TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]
D 122483478 tripartite motif-containing protein 5-like K10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
D 122483476 tripartite motif-containing protein 34-like K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 122483477 TRIM6; tripartite motif-containing protein 6 K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D 122485764 TRIM7; E3 ubiquitin-protein ligase TRIM7 isoform X1 K12000 TRIM7; tripartite motif-containing protein 7
D 122493188 TRIM8; E3 ubiquitin-protein ligase TRIM8 K12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
D 122469082 TRIM9; E3 ubiquitin-protein ligase TRIM9 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 122492750 TRIM67; tripartite motif-containing protein 67 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 122489055 tripartite motif-containing protein 10-like K12002 TRIM10; tripartite motif-containing protein 10
D 122485421 TRIM11; E3 ubiquitin-protein ligase TRIM11 K10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]
D 122481961 TRIM13; E3 ubiquitin-protein ligase TRIM13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 122474610 TRIM14; tripartite motif-containing protein 14 isoform X1 K12004 TRIM14; tripartite motif-containing protein 14
D 122484990 TRIM16; tripartite motif-containing protein 16 isoform X1 K12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]
D 122485403 TRIM17; E3 ubiquitin-protein ligase TRIM17 isoform X1 K12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]
D 122477216 MID1; E3 ubiquitin-protein ligase Midline-1 isoform X1 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 122483411 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
D 122489457 TRIM23; E3 ubiquitin-protein ligase TRIM23 isoform X1 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 122488376 TRIM24; transcription intermediary factor 1-alpha isoform X1 K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 122485344 TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 122485883 E3 ubiquitin-protein ligase TRIM47-like isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 122489050 tripartite motif-containing protein 26 K12008 TRIM26; tripartite motif-containing protein 26
D 122489076 TRIM27; zinc finger protein RFP K12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]
D 122494643 TRIM28; transcription intermediary factor 1-beta isoform X1 K08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]
D 122483073 TRIM29; tripartite motif-containing protein 29 K12010 TRIM29; tripartite motif-containing protein 29
D 122474735 TRIM32; E3 ubiquitin-protein ligase TRIM32 K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
D 122480971 TRIM33; E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 122473836 TRIM35; E3 ubiquitin-protein ligase TRIM35 isoform X1 K12012 TRIM35; tripartite motif-containing protein 35
D 122496739 TRIM36; E3 ubiquitin-protein ligase TRIM36 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 122485313 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 122490269 TRIM38; E3 ubiquitin-protein ligase TRIM38 isoform X1 K12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]
D 122489312 E3 ubiquitin-protein ligase TRIM39 isoform X1 K12015 TRIM39; tripartite motif-containing protein 39 / bloodthirsty-related gene family protein [EC:2.3.2.27]
D 122485740 TRIM41; E3 ubiquitin-protein ligase TRIM41 isoform X1 K12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
D 122491926 TRIM42; tripartite motif-containing protein 42 K12018 TRIM42; tripartite motif-containing protein 42
D 122482541 tripartite motif-containing protein 77-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 122482542 tripartite motif-containing protein 64-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 122483705 TRIM44; tripartite motif-containing protein 44 isoform X1 K12020 TRIM44; tripartite motif-containing protein 44
D 122481008 TRIM45; tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 122476369 TRIM46; tripartite motif-containing protein 46 isoform X1 K12022 TRIM46; tripartite motif-containing protein 46
D 122485917 TRIM47; E3 ubiquitin-protein ligase TRIM47 K12023 TRIM47; tripartite motif-containing protein 47
D 122471358 TRIM50; E3 ubiquitin-protein ligase TRIM50 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 122485791 E3 ubiquitin-protein ligase TRIM52-like isoform X1 K12025 TRIM52; tripartite motif-containing protein 52
D 122497333 TRIM54; tripartite motif-containing protein 54 K10653 TRIM54; tripartite motif-containing protein 54
D 122496018 TRIM55; tripartite motif-containing protein 55 isoform X1 K10654 TRIM55; tripartite motif-containing protein 55
D 122471309 TRIM56; E3 ubiquitin-protein ligase TRIM56 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 122470096 TRIM58; E3 ubiquitin-protein ligase TRIM58 K12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
D 122491785 TRIM59; tripartite motif-containing protein 59 K12028 TRIM59; tripartite motif-containing protein 59
D 122467515 TRIM61; LOW QUALITY PROTEIN: putative tripartite motif-containing protein 61 K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 122467745 tripartite motif-containing protein 60-like K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 122474853 tripartite motif-containing protein 60-like K12029 TRIM60_61; tripartite motif-containing protein 60/61
D 122482122 TRIM62; E3 ubiquitin-protein ligase TRIM62 isoform X1 K12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
D 122480111 TRIM63; E3 ubiquitin-protein ligase TRIM63 isoform X1 K10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]
D 122485918 TRIM65; tripartite motif-containing protein 65 isoform X1 K12031 TRIM65; tripartite motif-containing protein 65
D 122483533 TRIM66; tripartite motif-containing protein 66 isoform X1 K12032 TRIM66; tripartite motif-containing protein 66
D 122483418 TRIM68; E3 ubiquitin-protein ligase TRIM68 isoform X1 K12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]
D 122468703 TRIM69; E3 ubiquitin-protein ligase TRIM69 isoform X1 K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
D 122492188 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 122471412 TRIM72; tripartite motif-containing protein 72 K12036 TRIM72; tripartite motif-containing protein 72
D 122468837 LOW QUALITY PROTEIN: putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 122468865 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
D 122474846 putative tripartite motif-containing protein 75 K12037 TRIM75; tripartite motif-containing protein 75
C UBR box proteins
D 122467641 UBR1; E3 ubiquitin-protein ligase UBR1 K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D 122489523 UBR2; E3 ubiquitin-protein ligase UBR2 isoform X1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 122481437 UBR3; E3 ubiquitin-protein ligase UBR3 isoform X1 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 122480009 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X1 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 122469471 UBR7; putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 122494225 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 122492243 AIRE; autoimmune regulator K10603 AIRE; autoimmune regulator
D 122471642 BFAR; bifunctional apoptosis regulator isoform X1 K15684 BFAR; bifunctional apoptosis regulator
D 122482885 baculoviral IAP repeat-containing protein 3-like K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 122482886 BIRC2; baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 122477723 E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 122467169 BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 122470227 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 122485639 BRCA1; breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 122487739 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 122467666 CCNB1IP1; E3 ubiquitin-protein ligase CCNB1IP1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 122470082 CHFR; E3 ubiquitin-protein ligase CHFR isoform X1 K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 122488326 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 122476279 DCST1; E3 ubiquitin-protein ligase DCST1 isoform X1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 122470246 DTX1; E3 ubiquitin-protein ligase DTX1 K06058 DTX; deltex [EC:2.3.2.27]
D 122471340 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 122473823 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 122483808 DTX4; E3 ubiquitin-protein ligase DTX4 K06058 DTX; deltex [EC:2.3.2.27]
D 122491510 DTX3L; E3 ubiquitin-protein ligase DTX3L K06058 DTX; deltex [EC:2.3.2.27]
D 122491408 DZIP3; E3 ubiquitin-protein ligase DZIP3 isoform X1 K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
D 122496871 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 122497093 KCMF1; E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 122475433 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 isoform X1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 122491265 LTN1; E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 122489134 MAP3K1; mitogen-activated protein kinase kinase kinase 1 isoform X1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 122468182 MEX3B; LOW QUALITY PROTEIN: RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 122470777 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 122475780 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 122486531 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 122471715 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X1 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 122470630 MIB1; E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 122479798 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 122468340 MKRN3; probable E3 ubiquitin-protein ligase makorin-3 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 122487522 MKRN2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 122488400 MKRN1; E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 122480036 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 122483640 MYCBP2; E3 ubiquitin-protein ligase MYCBP2 isoform X1 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 122489212 E3 ubiquitin-protein ligase MYLIP isoform X1 K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 122492222 NEURL1B; E3 ubiquitin-protein ligase NEURL1B K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 122493212 NEURL1; E3 ubiquitin-protein ligase NEURL1 isoform X1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 122497222 NEURL3; E3 ubiquitin-protein ligase NEURL3 K15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
D 122489196 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 122483805 OBI1; ORC ubiquitin ligase 1 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 122477292 PJA1; E3 ubiquitin-protein ligase Praja-1 isoform X1 K10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]
D 122491874 PJA2; E3 ubiquitin-protein ligase Praja-2 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 122487469 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 122483713 RAG1; V(D)J recombination-activating protein 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 122478787 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 122475135 RC3H2; roquin-2 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 122476167 RC3H1; roquin-1 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 122476004 COP1; E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 122494462 RFWD3; E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 122476336 RNF2; E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 122489391 RING1; E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 122468706 E3 ubiquitin-protein ligase RNF4-like K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 122479119 RNF4; E3 ubiquitin-protein ligase RNF4 isoform X1 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 122470963 RNF185; E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 122478249 RNF5; E3 ubiquitin-protein ligase RNF5 isoform X1 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 122480751 RNF6; E3 ubiquitin-protein ligase RNF6 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 122489462 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 122470312 RNF10; RING finger protein 10 isoform X1 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 122482158 RNF11; RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 122477731 E3 ubiquitin-protein ligase RLIM-like K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 122477752 RLIM; E3 ubiquitin-protein ligase RLIM K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 122491859 RNF13; E3 ubiquitin-protein ligase RNF13 isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 122481775 RNF25; E3 ubiquitin-protein ligase RNF25 isoform X1 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 122483061 RNF26; E3 ubiquitin-protein ligase RNF26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 122474990 RNF38; E3 ubiquitin-protein ligase RNF38 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 122492310 RNF44; RING finger protein 44 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 122473760 RNF41; E3 ubiquitin-protein ligase NRDP1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 122485323 RNF43; E3 ubiquitin-protein ligase RNF43 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 122497139 E3 ubiquitin-protein ligase RNF103 isoform X1 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 122468578 RNF111; E3 ubiquitin-protein ligase Arkadia isoform X1 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 122485024 RNF112; RING finger protein 112 isoform X1 K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 122467284 RNF114; E3 ubiquitin-protein ligase RNF114 K15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
D 122481061 RNF115; E3 ubiquitin-protein ligase RNF115 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 122486610 RNF126; E3 ubiquitin-protein ligase RNF126 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 122475290 RNF175; RING finger protein 175 isoform X1 K15698 RNF121_175; RING finger protein 121/175
D 122483388 RNF121; RING finger protein 121 isoform X1 K15698 RNF121_175; RING finger protein 121/175
D 122473809 RNF122; RING finger protein 122 isoform X1 K15699 RNF122; RING finger protein 122
D 122488714 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 122470681 RNF125; E3 ubiquitin-protein ligase RNF125 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 122476920 RNF128; E3 ubiquitin-protein ligase RNF128 isoform X1 K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 122485919 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X1 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 122488157 RNF133; E3 ubiquitin-protein ligase RNF133 K15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]
D 122485207 RNF135; E3 ubiquitin-protein ligase RNF135 K16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]
D 122470682 RNF138; E3 ubiquitin-protein ligase RNF138 isoform X1 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 122495794 RNF139; E3 ubiquitin-protein ligase RNF139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 122493058 RNF145; RING finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 122489963 RNF146; E3 ubiquitin-protein ligase RNF146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 122496704 RNF149; E3 ubiquitin-protein ligase RNF149 isoform X1 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 122470821 RNF152; E3 ubiquitin-protein ligase RNF152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 122486112 RNF157; LOW QUALITY PROTEIN: E3 ubiquitin ligase RNF157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 122470738 RNF165; E3 ubiquitin-protein ligase RNF165 K17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
D 122494601 RNF166; E3 ubiquitin-protein ligase RNF166 isoform X1 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 122479747 E3 ubiquitin-protein ligase RNF167-like K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 122484812 RNF167; E3 ubiquitin-protein ligase RNF167 isoform X1 K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 122472859 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X1 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 122489394 RNF180; E3 ubiquitin-protein ligase RNF180 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 122497116 RNF181; E3 ubiquitin-protein ligase RNF181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 122489222 RNF182; E3 ubiquitin-protein ligase RNF182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 122479553 RNF186; E3 ubiquitin-protein ligase RNF186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 122485380 RNF187; E3 ubiquitin-protein ligase RNF187 K15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]
D 122486171 RNF213; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF213 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 122480400 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 122485298 RNFT1; E3 ubiquitin-protein ligase RNFT1 isoform X1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 122470268 RNFT2; RING finger and transmembrane domain-containing protein 2 K28516 RNFT2; E3 ubiquitin-protein ligase RNFT2
D 122484491 SART1; U4/U6.U5 tri-snRNP-associated protein 1 isoform X1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 122490064 SHPRH; E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 122474749 SH3RF1; E3 ubiquitin-protein ligase SH3RF1 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 122488589 SH3RF2; E3 ubiquitin-protein ligase SH3RF2 isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 122497560 SH3RF3; E3 ubiquitin-protein ligase SH3RF3 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 122491873 HLTF; helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 122483996 SYVN1; E3 ubiquitin-protein ligase synoviolin isoform X1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 122479138 TMEM129; E3 ubiquitin-protein ligase TM129 isoform X1 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 122475204 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 122488725 E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 122491176 TTC3; E3 ubiquitin-protein ligase TTC3 isoform X1 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 122486743 UHRF1; E3 ubiquitin-protein ligase UHRF1 isoform X1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 122474666 UHRF2; E3 ubiquitin-protein ligase UHRF2 isoform X1 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 122471870 UNKL; putative E3 ubiquitin-protein ligase UNKL isoform X1 K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 122471829 ZNF598; E3 ubiquitin-protein ligase ZNF598 isoform X1 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 122483799 ZFP91; E3 ubiquitin-protein ligase ZFP91 isoform X1 K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 122488062 ZNRF2; E3 ubiquitin-protein ligase ZNRF2 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 122494467 ZNRF1; E3 ubiquitin-protein ligase ZNRF1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 122470424 ZNRF3; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF3 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 122486753 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
D 122481547 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C 122487436 JADE2; E3 ubiquitin-protein ligase Jade-2 isoform X1 K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
C 122471807 E4F1; transcription factor E4F1 isoform X1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 122471529 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 122469368 IRF2BPL; probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
C 122494924 IRF2BP1; interferon regulatory factor 2-binding protein 1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 122475204 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 122497563 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 122467619 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 122470741 PIAS2; E3 SUMO-protein ligase PIAS2 isoform X1 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 122481057 PIAS3; E3 SUMO-protein ligase PIAS3 isoform X1 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 122486706 PIAS4; LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS4 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 122468444 PML; protein PML isoform X1 K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 122486179 CBX4; E3 SUMO-protein ligase CBX4 K11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
C 122495803 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 122468893 RNF212B; RING finger protein 212B K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 122479150 RNF212; probable E3 SUMO-protein ligase RNF212 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 122477472 ZBED1; E3 SUMO-protein ligase ZBED1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 122489653 ZNF451; E3 SUMO-protein ligase ZNF451 isoform X1 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 122478666 HERC5; E3 ISG15--protein ligase HERC5 isoform X1 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 122478667 HERC6; probable E3 ubiquitin-protein ligase HERC6 isoform X1 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 122489777 UFL1; E3 UFM1-protein ligase 1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 122485114 DCUN1D2; DCN1-like protein 2 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 122491687 DCUN1D1; DCN1-like protein 1 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 122471590 DCUN1D3; DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 122478896 DCUN1D4; DCN1-like protein 4 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 122482895 DCUN1D5; DCN1-like protein 5 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit type E3
C SCF complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122488471 CUL1; cullin-1 isoform X1 K03347 CUL1; cullin 1
D Adaptor protein
E 122483174 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 122487406 SKP1; LOW QUALITY PROTEIN: S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 122492298 FBXW11; F-box/WD repeat-containing protein 11 isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 122493158 BTRC; F-box/WD repeat-containing protein 1A isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 122475084 FBXW2; F-box/WD repeat-containing protein 2 isoform X1 K10261 FBXW2; F-box and WD-40 domain protein 2
E 122493160 FBXW4; F-box/WD repeat-containing protein 4 isoform X1 K10262 FBXW4; F-box and WD-40 domain protein 4
E 122474993 FBXW5; F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 122475466 FBXW7; F-box/WD repeat-containing protein 7 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 122470270 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 122486921 FBXW9; F-box/WD repeat-containing protein 9 K10265 FBXW9; F-box and WD-40 domain protein 9
E 122484988 CDRT1; CMT1A duplicated region transcript 1 protein isoform X1 K10266 FBXW10; F-box and WD-40 domain protein 10
E 122475061 F-box/WD repeat-containing protein 12-like isoform X1 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 122487219 FBXW12; F-box/WD repeat-containing protein 12 isoform X1 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 122494612 SKP2; S-phase kinase-associated protein 2 isoform X1 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 122485473 FBXL20; F-box/LRR-repeat protein 20 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 122492198 FBXL2; F-box/LRR-repeat protein 2 isoform X1 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 122483616 FBXL3; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 3 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 122489791 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 122479024 FBXL5; F-box/LRR-repeat protein 5 isoform X1 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 122495931 FBXL6; F-box/LRR-repeat protein 6 isoform X1 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 122495173 FBXL7; F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 122494373 FBXL8; F-box/LRR-repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 122494379 LRRC29; leucine-rich repeat-containing protein 29 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 122470195 KDM2B; lysine-specific demethylase 2B isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 122484041 KDM2A; lysine-specific demethylase 2A isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 122486838 FBXL12; F-box/LRR-repeat protein 12 isoform X1 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 122487789 FBXL13; dynein regulatory complex subunit 6 K10279 FBXL13; dynein regulatory complex subunit 6
E 122473282 FBXL14; F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 122493184 FBXL15; F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 122471907 FBXL16; F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 122491835 FBXL17; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 17 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 122471242 FBXL18; F-box/LRR-repeat protein 18 isoform X1 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 122471429 FBXL19; F-box/LRR-repeat protein 19 isoform X1 K10285 FBXL19; F-box and leucine-rich repeat protein 19
E 122487646 F-box/LRR-repeat protein 21 K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 122468543 FBXL22; F-box and leucine-rich protein 22 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 122471804 CCNF; cyclin-F K10289 CCNF; F-box protein 1 (cyclin F)
E 122479924 FBXO2; F-box only protein 2 K10099 FBXO2; F-box protein 2
E 122483681 FBXO3; F-box only protein 3 K10290 FBXO3; F-box protein 3
E 122494193 FBXO4; LOW QUALITY PROTEIN: F-box only protein 4 K10291 FBXO4; F-box protein 4
E 122490112 FBXO5; F-box only protein 5 K10292 FBXO5; F-box protein 5
E 122479926 FBXO6; F-box only protein 6 K10100 FBXO6; F-box protein 6
E 122472674 FBXO7; F-box only protein 7 isoform X1 K10293 FBXO7; F-box protein 7
E 122474542 FBXO8; F-box only protein 8 K10294 FBXO8; F-box protein 8
E 122489631 FBXO9; F-box only protein 9 K10295 FBXO9; F-box protein 9
E 122474638 FBXO10; F-box only protein 10 isoform X1 K10296 FBXO10; F-box protein 10
E 122496825 FBXO11; LOW QUALITY PROTEIN: F-box only protein 11 K10297 FBXO11; F-box protein 11
E 122470864 FBXO15; F-box only protein 15 K10298 FBXO15; F-box protein 15
E 122474020 FBXO16; F-box only protein 16 isoform X1 K10299 FBXO16; F-box protein 16
E 122494078 FBXO17; F-box only protein 17 K10101 FBXO17; F-box protein 17
E 122472212 FBH1; F-box DNA helicase 1 isoform X1 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 122483541 LMO7; LIM domain only protein 7 isoform X1 K06084 LMO7; F-box protein 20
E 122470273 FBXO21; F-box only protein 21 isoform X1 K10301 FBXO21; F-box protein 21
E 122468369 FBXO22; F-box only protein 22 isoform X1 K10302 FBXO22; F-box protein 22
E 122491905 TSPAN17; tetraspanin-17 isoform X1 K10303 FBXO23; F-box protein 23
E 122471291 FBXO24; F-box only protein 24 isoform X1 K10304 FBXO24; F-box protein 24
E 122469881 FBXO25; F-box only protein 25 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 122495781 FBXO32; F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 122494076 FBXO27; F-box only protein 27 isoform X1 K10102 FBXO27; F-box protein 27
E 122476223 FBXO28; F-box only protein 28 isoform X1 K10306 FBXO28; F-box protein 28
E 122490063 FBXO30; F-box only protein 30 K10307 FBXO30; F-box protein 30
E 122494578 FBXO31; F-box only protein 31 isoform X1 K10308 FBXO31; F-box protein 31
E 122469033 FBXO33; F-box only protein 33 K10310 FBXO33; F-box protein 33
E 122469127 FBXO34; F-box only protein 34 isoform X1 K10311 FBXO34; F-box protein 34
E 122481876 FBXO36; F-box only protein 36 K10312 FBXO36; F-box protein 36
E 122493797 FBXO38; F-box only protein 38 isoform X1 K10313 FBXO38; F-box protein 38
E 122484779 FBXO39; F-box only protein 39 K10314 FBXO39; F-box protein 39
E 122491492 FBXO40; F-box only protein 40 K10315 FBXO40; F-box protein 40
E 122497005 FBXO41; F-box only protein 41 K10316 FBXO41; F-box protein 41
E 122479985 FBXO42; F-box only protein 42 K10317 FBXO42; F-box protein 42
E 122495987 FBXO43; LOW QUALITY PROTEIN: F-box only protein 43 K10318 FBXO43; F-box protein 43
E 122479925 FBXO44; F-box only protein 44 isoform X1 K10103 FBXO44; F-box protein 44
E 122491568 FBXO45; F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 122494923 FBXO46; F-box only protein 46 K10320 FBXO46; F-box protein 46
E 122485464 FBXO47; F-box only protein 47 K10321 FBXO47; F-box protein 47
E 122496939 FBXO48; F-box only protein 48 isoform X1 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122473249 CUL2; cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 122467740 elongin-C-like K03872 ELOC; elongin-C
E 122490554 elongin-C-like K03872 ELOC; elongin-C
E 122495495 ELOC; elongin-C isoform X1 K03872 ELOC; elongin-C
E 122471788 ELOB; elongin-B K03873 ELOB; elongin-B
E 122480776 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 122487498 VHL; von Hippel-Lindau disease tumor suppressor isoform X1 K03871 VHL; von Hippel-Lindau disease tumor supressor
E 122469054 LRR1; leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 122468903 FEM1C; protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 122486738 FEM1A; protein fem-1 homolog A K25805 FEM1A_C; protein fem-1 homolog A/C
E 122467621 FEM1B; protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 122485283 APPBP2; amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 122469062 KLHDC2; kelch domain-containing protein 2 K25807 KLHDC2; kelch domain-containing protein 2
E 122489534 KLHDC3; kelch domain-containing protein 3 isoform X1 K25808 KLHDC3; kelch domain-containing protein 3
E 122488266 KLHDC10; kelch domain-containing protein 10 isoform X1 K25809 KLHDC10; kelch domain-containing protein 10
E 122474844 ZER1; protein zer-1 homolog isoform X1 K10350 ZYG11; Zyg-11 protein
E 122479397 ZYG11A; LOW QUALITY PROTEIN: protein zyg-11 homolog A K10350 ZYG11; Zyg-11 protein
E 122480508 ZYG11B; protein zyg-11 homolog B K10350 ZYG11; Zyg-11 protein
E 122493461 ZSWIM8; zinc finger SWIM domain-containing protein 8 isoform X1 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
E 122470387 PRAME; melanoma antigen preferentially expressed in tumors isoform X1 K28155 PRAME; melanoma antigen preferentially expressed in tumors
C Cul3 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122481845 CUL3; cullin-3 isoform X1 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 122467032 KLHL5; kelch-like protein 5 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 122477096 KLHL4; LOW QUALITY PROTEIN: kelch-like protein 4 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 122483379 KLHL1; kelch-like protein 1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 122474835 KLHL2; kelch-like protein 2 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 122487759 KLHL3; kelch-like protein 3 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 122491680 KLHL6; kelch-like protein 6 K10444 KLHL6; kelch-like protein 6
E 122487993 KLHL7; kelch-like protein 7 isoform X1 K10445 KLHL7; kelch-like protein 7
E 122478683 KLHL8; kelch-like protein 8 isoform X1 K10446 KLHL8; kelch-like protein 8
E 122475418 KLHL9; kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 122477774 KLHL13; kelch-like protein 13 isoform X1 K10447 KLHL9_13; kelch-like protein 9/13
E 122485583 KLHL10; kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 122485582 KLHL11; kelch-like protein 11 K10449 KLHL11; kelch-like protein 11
E 122476008 KLHL12; kelch-like protein 12 isoform X1 K10450 KLHL12; kelch-like protein 12
E 122470685 KLHL14; kelch-like protein 14 K10451 KLHL14; kelch-like protein 14
E 122477500 KLHL15; kelch-like protein 15 K10452 KLHL15; kelch-like protein 15
E 122494510 GAN; gigaxonin K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 122479759 KLHL17; kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 122487201 KLHL18; kelch-like protein 18 isoform X1 K10455 KLHL18; kelch-like protein 18
E 122486862 KEAP1; kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 122475829 KLHL20; kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 122479872 KLHL21; kelch-like protein 21 K10458 KLHL21; kelch-like protein 21
E 122470478 KLHL22; kelch-like protein 22 K10459 KLHL22; kelch-like protein 22
E 122481434 KLHL23; kelch-like protein 23 K10460 KLHL23; kelch-like protein 23
E 122483331 KLHL35; kelch-like protein 35 K10461 KLHL24_35; kelch-like protein 24/35
E 122491679 KLHL24; kelch-like protein 24 isoform X1 K10461 KLHL24_35; kelch-like protein 24/35
E 122468255 KLHL25; kelch-like protein 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 122489773 ENC1; ectoderm-neural cortex protein 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 122487121 KLHL26; kelch-like protein 26 isoform X1 K10463 KLHL26; kelch-like protein 26
E 122480436 actin-binding protein IPP isoform X1 K13956 IPP; actin-binding protein IPP
E 122469041 KLHL28; kelch-like protein 28 isoform X1 K10464 KLHL28; kelch-like protein 28
E 122497403 KLHL29; kelch-like protein 29 isoform X1 K10465 KLHL29; kelch-like protein 29
E 122481968 KLHL30; kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 122489636 KLHL31; kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 122489786 KLHL32; kelch-like protein 32 isoform X1 K10468 KLHL32; kelch-like protein 32
E 122467671 KLHL33; kelch-like protein 33 K13957 KLHL33; kelch-like protein 33
E 122477672 KLHL34; kelch-like protein 34 K10469 KLHL34; kelch-like protein 34
E 122494551 KLHL36; kelch-like protein 36 K13958 KLHL36; kelch-like protein 36
E 122495782 KLHL38; kelch-like protein 38 K13959 KLHL38; kelch-like protein 38
E 122472276 KLHL42; kelch-like protein 42 K27973 KLHL42; kelch-like protein 42
E 122488079 KBTBD2; kelch repeat and BTB domain-containing protein 2 K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E 122482904 KBTBD3; kelch repeat and BTB domain-containing protein 3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 122484448 KBTBD4; kelch repeat and BTB domain-containing protein 4 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 122481426 KLHL41; kelch-like protein 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 122492101 KLHL40; kelch-like protein 40 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 122483168 KBTBD7; kelch repeat and BTB domain-containing protein 7 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 122483177 kelch repeat and BTB domain-containing protein 6 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 122487410 KBTBD8; kelch repeat and BTB domain-containing protein 8 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 122470127 KBTBD11; kelch repeat and BTB domain-containing protein 11 K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E 122487592 KBTBD12; kelch repeat and BTB domain-containing protein 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 122468511 KBTBD13; kelch repeat and BTB domain-containing protein 13 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 122468199 BTBD1; BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 122486631 BTBD2; BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 122469607 BTBD6; BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 122496576 BTBD3; BTB/POZ domain-containing protein 3 isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 122469470 BTBD7; BTB/POZ domain-containing protein 7 isoform X1 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 122480770 BTBD8; BTB/POZ domain-containing protein 8 isoform X1 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 122489473 BTBD9; BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 122483579 BTBD10; BTB/POZ domain-containing protein 10 isoform X1 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 122472666 BTBD11; ankyrin repeat and BTB/POZ domain-containing protein BTBD11 K10483 BTBD11; BTB/POZ domain-containing protein 11
E 122471742 SLX4; structure-specific endonuclease subunit SLX4 isoform X1 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 122496957 GMCL1; germ cell-less protein-like 1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 122474989 NACC2; nucleus accumbens-associated protein 2 isoform X1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 122486951 NACC1; nucleus accumbens-associated protein 1 isoform X1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 122493329 BTBD16; BTB/POZ domain-containing protein 16 isoform X1 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 122469210 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 122490100 ZBTB2; zinc finger and BTB domain-containing protein 2 isoform X1 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 122483905 ZBTB3; zinc finger and BTB domain-containing protein 3 K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E 122484876 ZBTB4; zinc finger and BTB domain-containing protein 4 K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
E 122474635 ZBTB5; zinc finger and BTB domain-containing protein 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 122474954 ZBTB6; zinc finger and BTB domain-containing protein 6 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 122470749 ZBTB7C; zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 122476280 ZBTB7B; zinc finger and BTB domain-containing protein 7B K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 122486705 ZBTB7A; zinc finger and BTB domain-containing protein 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 122480243 ZBTB8B; zinc finger and BTB domain-containing protein 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 122480244 ZBTB8A; zinc finger and BTB domain-containing protein 8A K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 122489410 ZBTB9; zinc finger and BTB domain-containing protein 9 K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E 122495522 ZBTB10; zinc finger and BTB domain-containing protein 10 isoform X1 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 122491384 ZBTB11; zinc finger and BTB domain-containing protein 11 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 122478266 ZBTB12; zinc finger and BTB domain-containing protein 12 K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E 122482982 ZBTB16; zinc finger and BTB domain-containing protein 16 K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
E 122479975 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 122492265 ZBTB20; zinc finger and BTB domain-containing protein 20 isoform X1 K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
E 122489395 ZBTB22; zinc finger and BTB domain-containing protein 22 K10502 ZBTB22; zinc finger and BTB domain-containing protein 22
E 122489851 ZBTB24; zinc finger and BTB domain-containing protein 24 isoform X1 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 122469208 ZBTB25; zinc finger and BTB domain-containing protein 25 isoform X1 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 122474953 ZBTB26; zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 122495004 ZBTB32; zinc finger and BTB domain-containing protein 32 K10506 ZBTB32; zinc finger and BTB domain-containing protein 32
E 122477994 ZBTB33; transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 122475085 ZBTB34; zinc finger and BTB domain-containing protein 34 isoform X1 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E 122475832 ZBTB37; zinc finger and BTB domain-containing protein 37 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 122491920 ZBTB38; zinc finger and BTB domain-containing protein 38 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 122473796 ZBTB39; zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 122480070 ZBTB40; zinc finger and BTB domain-containing protein 40 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E 122476429 ZBTB41; zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 122475086 ZBTB43; zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 122483152 ZBTB44; zinc finger and BTB domain-containing protein 44 isoform X1 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 122494660 ZBTB45; zinc finger and BTB domain-containing protein 45 K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
E 122467143 ZBTB46; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 122492105 ZBTB47; zinc finger and BTB domain-containing protein 47 isoform X1 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E 122479869 ZBTB48; telomere zinc finger-associated protein K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 122487596 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 122483690 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 122472257 RHOBTB2; rho-related BTB domain-containing protein 2 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 122492785 RHOBTB1; rho-related BTB domain-containing protein 1 isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 122491360 RHOBTB3; rho-related BTB domain-containing protein 3 isoform X1 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 122470349 KCTD10; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 122471480 KCTD13; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 122485174 TNFAIP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 122470660 KCTD1; BTB/POZ domain-containing protein KCTD1 isoform X1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 122494132 KCTD15; BTB/POZ domain-containing protein KCTD15 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 122471799 KCTD5; BTB/POZ domain-containing protein KCTD5 isoform X1 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 122472704 KCTD17; BTB/POZ domain-containing protein KCTD17 isoform X1 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 122485879 KCTD2; BTB/POZ domain-containing protein KCTD2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 122476329 KCTD3; BTB/POZ domain-containing protein KCTD3 isoform X1 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 122487372 KCTD6; BTB/POZ domain-containing protein KCTD6 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 122471379 KCTD7; BTB/POZ domain-containing protein KCTD7 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 122483292 KCTD14; BTB/POZ domain-containing protein KCTD14 isoform X1 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 122478935 KCTD8; BTB/POZ domain-containing protein KCTD8 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 122483614 KCTD12; BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 122488554 KCTD16; BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 122472092 KCTD9; BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 122484867 KCTD11; BTB/POZ domain-containing protein KCTD11 K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 122481626 KCTD18; BTB/POZ domain-containing protein KCTD18 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 122483287 KCTD21; BTB/POZ domain-containing protein KCTD21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 122470177 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
E 122481294 SPOPL; speckle-type POZ protein-like K10523 SPOP; speckle-type POZ protein
E 122485392 speckle-type POZ protein isoform X1 K10523 SPOP; speckle-type POZ protein
E 122470493 LZTR1; leucine-zipper-like transcriptional regulator 1 isoform X1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122477857 CUL4B; cullin-4B isoform X1 K10609 CUL4; cullin 4
E 122485011 CUL4A; cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 122483848 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 122484438 DDB2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E 122489283 ERCC8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E 122468248 DET1; DET1 homolog isoform X1 K10571 DET1; de-etiolated-1
E 122476004 COP1; E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 122487061 DDA1; DET1- and DDB1-associated protein 1 isoform X1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 122487452 CRBN; protein cereblon isoform X1 K11793 CRBN; cereblon
E 122476069 torsin-1A-interacting protein 2 K11794 IFRG15; IFRG15 protein
E 122497533 short transient receptor potential channel 4-associated protein isoform X1 K11796 TRPC4AP; Trpc4-associated protein
E 122487274 DCAF1; DDB1- and CUL4-associated factor 1 isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 122476413 DTL; denticleless protein homolog K11790 DTL; denticleless
E 122469285 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 122467780 DCAF5; DDB1- and CUL4-associated factor 5 isoform X1 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 122475645 DCAF6; DDB1- and CUL4-associated factor 6 isoform X1 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 122485759 DCAF7; DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 122476355 DCAF8; DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 122477482 DDB1- and CUL4-associated factor 8-like K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 122480147 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 122474646 DCAF10; DDB1- and CUL4-associated factor 10 isoform X1 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 122468921 DCAF11; DDB1- and CUL4-associated factor 11 isoform X1 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 122474896 DCAF12; DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 122477322 DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 122478028 DDB1- and CUL4-associated factor 12-like protein 2 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 122495695 DCAF13; DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 122489714 PH-interacting protein isoform X1 K11797 PHIP; PH-interacting protein
E 122486973 DCAF15; DDB1- and CUL4-associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 122479005 DCAF16; DDB1- and CUL4-associated factor 16 isoform X1 K23626 DCAF16; DDB1- and CUL4-associated factor 16
E 122481445 DCAF17; DDB1- and CUL4-associated factor 17 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 122477616 BRWD3; bromodomain and WD repeat-containing protein 3 isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 122491163 BRWD1; bromodomain and WD repeat-containing protein 1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 122475850 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
E 122494486 WDR70; WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 122468717 WDR76; WD repeat-containing protein 76 isoform X1 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 122491915 RNF7; RING-box protein 2 isoform X1 K10611 RBX2; RING-box protein 2
D Cullin
E 122482917 CUL5; cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 122467740 elongin-C-like K03872 ELOC; elongin-C
E 122490554 elongin-C-like K03872 ELOC; elongin-C
E 122495495 ELOC; elongin-C isoform X1 K03872 ELOC; elongin-C
E 122471788 ELOB; elongin-B K03873 ELOB; elongin-B
E 122480776 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 122487269 CISH; cytokine-inducible SH2-containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 122471669 SOCS1; suppressor of cytokine signaling 1 K04694 SOCS1; suppressor of cytokine signaling 1
E 122472490 SOCS2; suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 122486151 SOCS3; suppressor of cytokine signaling 3 K04696 SOCS3; suppressor of cytokine signaling 3
E 122469118 SOCS4; suppressor of cytokine signaling 4 K04697 SOCS4; suppressor of cytokine signaling 4
E 122496807 SOCS5; LOW QUALITY PROTEIN: suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 122470858 SOCS6; suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 122485450 SOCS7; suppressor of cytokine signaling 7 isoform X1 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 122481977 ASB1; ankyrin repeat and SOCS box protein 1 isoform X1 K10323 ASB1; ankyrin repeat and SOCS box protein 1
E 122469479 ASB2; ankyrin repeat and SOCS box protein 2 isoform X1 K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 122496838 ASB3; ankyrin repeat and SOCS box protein 3 isoform X1 K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 122487900 ASB4; ankyrin repeat and SOCS box protein 4 K10326 ASB4; ankyrin repeat and SOCS box protein 4
E 122470367 ASB5; ankyrin repeat and SOCS box protein 5 isoform X1 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 122474770 ASB6; ankyrin repeat and SOCS box protein 6 isoform X1 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 122468305 ASB7; ankyrin repeat and SOCS box protein 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 122473340 ASB8; ankyrin repeat and SOCS box protein 8 isoform X1 K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 122476998 ASB9; ankyrin repeat and SOCS box protein 9 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 122488537 ASB10; ankyrin repeat and SOCS box protein 10 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 122477203 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1 K10333 ASB11; ankyrin repeat and SOCS box protein 11
E 122477377 ASB12; ankyrin repeat and SOCS box protein 12 isoform X1 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 122474011 ASB13; ankyrin repeat and SOCS box protein 13 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 122487351 ASB14; ankyrin repeat and SOCS box protein 14 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 122488164 ASB15; ankyrin repeat and SOCS box protein 15 isoform X1 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 122485672 ASB16; ankyrin repeat and SOCS box protein 16 K10338 ASB16; ankyrin repeat and SOCS box protein 16
E 122480655 ASB17; ankyrin repeat and SOCS box protein 17 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 122481948 ASB18; ankyrin repeat and SOCS box protein 18 K10340 ASB18; ankyrin repeat and SOCS box protein 18
E 122485188 WSB1; WD repeat and SOCS box-containing protein 1 isoform X1 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 122470278 WSB2; WD repeat and SOCS box-containing protein 2 isoform X1 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 122479906 SPSB1; SPRY domain-containing SOCS box protein 1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 122491924 SPSB4; SPRY domain-containing SOCS box protein 4 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 122472385 SPSB2; SPRY domain-containing SOCS box protein 2 K10344 SPSB2; SPRY domain-containing SOCS box protein 2
E 122471849 SPSB3; SPRY domain-containing SOCS box protein 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 122471914 RAB40C; ras-related protein Rab-40C isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 122485991 RAB40B; ras-related protein Rab-40B isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 122480446 LRRC41; leucine-rich repeat-containing protein 41 isoform X1 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 122494243 RSPRY1; RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 122469569 ANKRD9; ankyrin repeat domain-containing protein 9 K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 122469059 KLHDC1; kelch domain-containing protein 1 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122489537 CUL7; cullin-7 K10613 CUL7; cullin 7
D Adaptor protein
E 122483174 S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
E 122487406 SKP1; LOW QUALITY PROTEIN: S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 122470270 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 122472803 RBX1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 122489542 CUL9; cullin-9 isoform X1 K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
E 122485960 ANAPC11; anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 122475282 ANAPC2; anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 122480379 CDC20; cell division cycle protein 20 homolog isoform X1 K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 122486686 FZR1; fizzy-related protein homolog isoform X1 K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 122497186 ANAPC1; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 122485738 CDC27; cell division cycle protein 27 homolog isoform X1 K03350 APC3; anaphase-promoting complex subunit 3
E 122478984 ANAPC4; anaphase-promoting complex subunit 4 isoform X1 K03351 APC4; anaphase-promoting complex subunit 4
E 122470199 ANAPC5; anaphase-promoting complex subunit 5 isoform X1 K03352 APC5; anaphase-promoting complex subunit 5
E 122485220 CDC16; cell division cycle protein 16 homolog isoform X1 K03353 APC6; anaphase-promoting complex subunit 6
E 122470207 ANAPC7; anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 122487866 CDC23; cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 122475941 ANAPC10; anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
E 122475385 CDC26; anaphase-promoting complex subunit CDC26 K03359 APC12; anaphase-promoting complex subunit 12
E 122491967 ANAPC13; anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 122483394 ANAPC15; anaphase-promoting complex subunit 15 isoform X1 K25228 APC15; anaphase-promoting complex subunit 15
E 122492870 ANAPC16; anaphase-promoting complex subunit 16 isoform X1 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 122485639 BRCA1; breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 122481231 BRCA2; breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
D 122477873 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 122481733 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 122497311 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
D 122468767 RAD51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 122488714 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 122475353 UBAC1; ubiquitin-associated domain-containing protein 1 isoform X1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 122495922 SHARPIN; sharpin isoform X1 K20894 SHARPIN; shank-associated RH domain-interacting protein
D 122496433 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 122468926 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 122486276 RMND5B; E3 ubiquitin-protein transferase RMND5B isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 122497141 RMND5A; E3 ubiquitin-protein transferase RMND5A isoform X1 K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 122489225 RANBP9; ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 122495115 RANBP10; ran-binding protein 10 K23334 RANBP9_10; Ran-binding protein 9/10
D 122491941 ARMC8; armadillo repeat-containing protein 8 isoform X1 K23336 ARMC8; armadillo repeat-containing protein 8
D 122488752 MKLN1; muskelin isoform X1 K23337 MKLN1; muskelin
D 122479144 MAEA; E3 ubiquitin-protein transferase MAEA isoform X1 K18624 MAEA; macrophage erythroblast attacher
D 122485045 GID4; glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 122467176 GID8; glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 122497293 YPEL5; protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 122475850 WDR26; WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 122494225 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 122485674 TMUB2; transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 122488534 TMUB1; transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 122473725 ERLIN2; erlin-2 K23341 ERLIN; erlin
D 122493132 ERLIN1; LOW QUALITY PROTEIN: erlin-1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 122472350 LMBR1L; protein LMBR1L K25215 LMBR1L; protein LMBR1L
D 122494225 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 122484283 UBAC2; ubiquitin-associated domain-containing protein 2 isoform X1 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C STUB1-CHIC2 complex
D 122471911 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
D 122478881 CHIC2; cysteine-rich hydrophobic domain-containing protein 2 isoform X1 K28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 122473952 CAND1; cullin-associated NEDD8-dissociated protein 1 isoform X1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 122487523 CAND2; cullin-associated NEDD8-dissociated protein 2 K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 122496893 COMMD1; COMM domain-containing protein 1 K22557 COMMD1; COMM domain containing 1
D 122491861 COMMD2; COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 122473715 COMMD3; COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 122468408 COMMD4; COMM domain-containing protein 4 isoform X1 K22560 COMMD4; COMM domain containing 4
D 122495952 COMMD5; COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 122483534 COMMD6; COMM domain-containing protein 6 K22562 COMMD6; COMM domain containing 6
D 122496384 COMMD7; COMM domain-containing protein 7 K22563 COMMD7; COMM domain containing 7
D 122478923 COMMD8; COMM domain-containing protein 8 isoform X1 K22564 COMMD8; COMM domain containing 8
D 122483709 COMMD9; COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 122477032 COMMD10; COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 122477613 CCDC22; coiled-coil domain-containing protein 22 K23343 CCDC22; coiled-coil domain-containing protein 22
D 122496502 DDRGK1; DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 122480772 GLMN; glomulin isoform X1 K23345 GLMN; glomulin
D 122476331 influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 122491562 UBXN7; UBX domain-containing protein 7 isoform X1 K24350 UBXN7; UBX domain-containing protein 7
D 122490162 PACRG; parkin coregulated gene protein K26163 PACRG; parkin coregulated gene protein
D 122474892 UBAP2; ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 122476461 UBAP2L; ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 122483601 UEVLD; LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 variant 3 K28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 122478948 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 122487305 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 122483511 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 122475764 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 122494192 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 122480583 USP1; ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 122483062 USP2; ubiquitin carboxyl-terminal hydrolase 2 isoform X1 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 122468542 USP3; ubiquitin carboxyl-terminal hydrolase 3 isoform X1 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 122476787 USP11; ubiquitin carboxyl-terminal hydrolase 11 isoform X1 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 122488704 USP4; ubiquitin carboxyl-terminal hydrolase 4 isoform X1 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 122472378 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X1 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 122491701 USP13; ubiquitin carboxyl-terminal hydrolase 13 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 122485281 USP32; ubiquitin carboxyl-terminal hydrolase 32 isoform X1 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 122471683 USP7; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 122468654 USP8; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 122477639 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 122480552 USP24; ubiquitin carboxyl-terminal hydrolase 24 isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 122494550 USP10; ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 122478889 USP46; ubiquitin carboxyl-terminal hydrolase 46 isoform X1 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 122480850 USP12; ubiquitin carboxyl-terminal hydrolase 12 isoform X1 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 122470621 USP14; ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 122473923 USP15; ubiquitin carboxyl-terminal hydrolase 15 isoform X1 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 122489794 USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 122491263 USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 122467470 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 17-like protein 6 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 122468512 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 17-like protein 13 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 122470242 ubiquitin carboxyl-terminal hydrolase 17-like protein 6 K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
D 122472199 USP18; ubl carboxyl-terminal hydrolase 18 isoform X1 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 122488690 USP19; ubiquitin carboxyl-terminal hydrolase 19 isoform X1 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 122474597 USP20; ubiquitin carboxyl-terminal hydrolase 20 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 122480669 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 122476134 USP21; ubiquitin carboxyl-terminal hydrolase 21 isoform X1 K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D 122476965 USP27X; ubiquitin carboxyl-terminal hydrolase 27 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 122477014 USP51; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 51 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 122485063 USP22; ubiquitin carboxyl-terminal hydrolase 22 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 122491293 USP25; ubiquitin carboxyl-terminal hydrolase 25 isoform X1 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 122477379 USP26; ubiquitin carboxyl-terminal hydrolase 26 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 122481767 USP37; ubiquitin carboxyl-terminal hydrolase 37 isoform X1 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 122482977 USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform X1 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 122470342 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 122471559 USP31; ubiquitin carboxyl-terminal hydrolase 31 isoform X1 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 122496887 USP34; ubiquitin carboxyl-terminal hydrolase 34 isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 122476027 USP38; ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 122483285 USP35; ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 122471264 USP42; ubiquitin carboxyl-terminal hydrolase 42 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 122486140 USP36; ubiquitin carboxyl-terminal hydrolase 36 isoform X1 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 122481929 USP40; ubiquitin carboxyl-terminal hydrolase 40 isoform X1 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 122484950 USP43; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 43 K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
D 122472519 USP44; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 44 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 122489508 USP49; ubiquitin carboxyl-terminal hydrolase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 122483570 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 122480061 USP48; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 48 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
D 122493455 USP54; inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1 K27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]
C OTU
D 122483942 OTUB1; ubiquitin thioesterase OTUB1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 122469482 OTUB2; ubiquitin thioesterase OTUB2 isoform X1 K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
D 122480027 OTUD3; OTU domain-containing protein 3 isoform X1 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 122476853 OTUD5; OTU domain-containing protein 5 isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 122477301 OTUD6A; OTU domain-containing protein 6A K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 122495587 OTUD6B; deubiquitinase OTUD6B isoform X1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 122468336 OTUD7A; OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 122481103 OTUD7B; OTU domain-containing protein 7B K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 122495212 OTULIN; ubiquitin thioesterase otulin isoform X1 K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
D 122490018 TNFAIP3; tumor necrosis factor alpha-induced protein 3 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 122496026 VCPIP1; deubiquitinating protein VCPIP1 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 122493362 ZRANB1; ubiquitin thioesterase ZRANB1 isoform X1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 122469456 ATXN3; ataxin-3 isoform X1 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 122472761 JOSD1; josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
D 122493815 JOSD2; josephin-2 isoform X1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 122468582 MINDY2; ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 122481140 MINDY1; ubiquitin carboxyl-terminal hydrolase MINDY-1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 122473205 MINDY3; ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 122488068 MINDY4; probable ubiquitin carboxyl-terminal hydrolase MINDY-4 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 122491021 MINDY4B; inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 122477873 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 122480567 MYSM1; deubiquitinase MYSM1 isoform X1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 122486726 MPND; MPN domain-containing protein isoform X1 K24173 MPND; MPN domain-containing protein
D 122481379 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 122497020 STAM-binding protein isoform X1 K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D 122493447 STAMBPL1; AMSH-like protease K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 122476234 DESI2; deubiquitinase DESI2 isoform X1 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 122489913 ZUP1; zinc finger-containing ubiquitin peptidase 1 isoform X1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 122493359 ABRAXAS2; BRISC complex subunit Abraxas 2 K20799 FAM175B; BRISC complex subunit Abro1
D 122487054 BABAM1; BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 122477873 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 122497311 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 122473339 SENP1; sentrin-specific protease 1 isoform X1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 122491643 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 122484888 SENP3; sentrin-specific protease 3 K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C 122491576 SENP5; sentrin-specific protease 5 isoform X1 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 122489705 SENP6; sentrin-specific protease 6 isoform X1 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 122491377 SENP7; LOW QUALITY PROTEIN: sentrin-specific protease 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 122467585 SENP8; sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 122483511 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 122472822 DESI1; desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 122481111 USPL1; SUMO-specific isopeptidase USPL1 isoform X1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 122485974 GPS1; COP9 signalosome complex subunit 1 isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 122468667 COPS2; COP9 signalosome complex subunit 2 isoform X1 K12176 COPS2; COP9 signalosome complex subunit 2
D 122485056 COPS3; COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 122478712 COPS4; COP9 signalosome complex subunit 4 isoform X1 K12178 COPS4; COP9 signalosome complex subunit 4
D 122496039 COPS5; COP9 signalosome complex subunit 5 isoform X1 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 122467640 LOW QUALITY PROTEIN: COP9 signalosome complex subunit 6-like K12179 COPS6; COP9 signalosome complex subunit 6
D 122471993 COPS6; COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 122472373 COPS7A; COP9 signalosome complex subunit 7a K12180 COPS7; COP9 signalosome complex subunit 7
D 122481906 COPS7B; COP9 signalosome complex subunit 7b isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 122481954 COPS8; COP9 signalosome complex subunit 8 isoform X1 K12181 COPS8; COP9 signalosome complex subunit 8
D 122481985 COPS9; COP9 signalosome complex subunit 9 K28062 COPS9; COP9 signalosome complex subunit 9
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 28, 2025