+F Repair protein KO
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DNA Repair and Recombination Proteins - Pieris brassicae (large cabbage white)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 123708186 LOW QUALITY PROTEIN: DNA oxidative demethylase ALKBH2-like K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 123720105 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 123714661 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 123715930 single-strand selective monofunctional uracil DNA glycosylase isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 123713495 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 123711580 recombination repair protein 1-like K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 123711484 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 123710467 DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
E DNA polymerase epsilon complex
F 123718092 DNA polymerase epsilon catalytic subunit 1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 123711179 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 123720155 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 123714166 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 123711765 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 123707626 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 123707468 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 123720096 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 123714561 DNA ligase 3 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 123718151 probable tyrosyl-DNA phosphodiesterase isoform X1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 123715748 aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 123709228 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 123710505 uncharacterized protein F21D5.5 isoform X1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 123711886 high mobility group protein DSP1-like isoform X1 K10802 HMGB1; high mobility group protein B1
E 123707093 poly [ADP-ribose] polymerase isoform X1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 123707168 poly [ADP-ribose] polymerase-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 123710932 UV excision repair protein RAD23 homolog A K10839 RAD23; UV excision repair protein RAD23
F 123718146 caltractin-like isoform X1 K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 123714871 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123714305 cullin-4A K10609 CUL4; cullin 4
F 123715959 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 123716696 DNA-directed RNA polymerase II subunit RPB1 isoform X1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 123706666 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 123720045 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 123709256 DNA-directed RNA polymerase II subunit Rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 123713359 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 123709833 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 123718411 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 123718076 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 123710310 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 123715665 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 123720139 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 123716269 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 123714871 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 123714305 cullin-4A K10609 CUL4; cullin 4
F 123715959 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F 123712124 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
F 123708124 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 123708687 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 123707843 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 123711437 general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 123710172 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 123712245 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 123715112 general transcription factor IIH subunit 4 isoform X1 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 123713070 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 123707325 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 123710339 cyclin-H K06634 CCNH; cyclin H
E 123711361 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 123710202 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123710235 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D Other NER factors
E 123714587 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 123709284 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 123720870 DNA repair endonuclease XPF isoform X1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 123707468 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 123713280 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 123711584 cullin-3-B isoform X1 K03869 CUL3; cullin 3
E 123713455 cullin-5 K10612 CUL5; cullin 5
E 123714495 elongin-C K03872 ELOC; elongin-C
E 123708753 elongin-B K03873 ELOB; elongin-B
E 123714383 transcription elongation factor B polypeptide 3 K15076 ELOA; elongin-A
E 123710643 protein lingerer isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 123712726 DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 123710054 probable DNA mismatch repair protein Msh6 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 123720427 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 123709767 mismatch repair endonuclease PMS2 isoform X1 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 123711484 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 123710467 DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
D RPA (replication factor A)
E 123710202 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123710235 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D RFC (replication factor C)
E 123708281 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 123712618 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 123717895 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 123720631 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 123709944 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 123711765 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 123710368 exonuclease 1 isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 123711886 high mobility group protein DSP1-like isoform X1 K10802 HMGB1; high mobility group protein B1
E 123707468 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 123712417 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123709352 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
E 123707820 BRISC and BRCA1-A complex member 2-like isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
E 123711227 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 123713054 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D BRCA1-C complex
E 123712417 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123709352 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E 123716657 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 123716657 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
D Rad52 family proteins
D Rad54 family proteins
E 123712715 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E 123711998 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 123707132 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123720094 ankyrin repeat domain-containing protein 11-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 123707132 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123708064 DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123711072 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123712790 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 123710202 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 123710235 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D Protein phosphatase 4
E 123709839 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 123716669 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E 123711051 structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 123713984 structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 123714184 uncharacterized protein LOC123714184 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 123711879 E3 SUMO-protein ligase NSE2-like isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 123713335 non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 123718075 EP300-interacting inhibitor of differentiation 3-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 123707922 exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 123713031 structure-specific endonuclease subunit SLX1 homolog K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 123717688 flap endonuclease GEN isoform X1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 123719176 spatacsin isoform X1 K19026 SPG11; spatacsin
E 123715909 zinc finger FYVE domain-containing protein 26 homolog isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 123706975 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 123709008 fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 123709327 biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
E 123712417 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 123709352 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
D X-family DNA polymerases
E 123720096 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 123715748 aprataxin K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 123709228 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E 123709881 centromere protein S-like K11511 APITD1; centromere protein S
E 123716326 centromere protein X-like K15360 STRA13; centromere protein X
E 123707524 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 123707132 Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 123708064 DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123711072 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 123712790 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 123714694 Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein
D Downstream FA components
E 123713054 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 123716657 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 123709536 probable ubiquitin carboxyl-terminal hydrolase 9 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 123711042 WD repeat-containing protein 48 homolog K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 123706942 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
E 123720572 E3 ubiquitin-protein ligase rnf8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 123717652 E3 ubiquitin-protein ligase RNF169-like isoform X1 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 123707649 probable E3 ubiquitin-protein ligase HERC2 isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 123707529 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 123708205 DNApol-eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 123715889 DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 123714003 DNA repair protein Rev1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D 123715092 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 123715625 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 123714554 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 123711765 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 123711305 uncharacterized protein LOC123711305 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 123710945 checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D 123709728 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 123712618 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 123717895 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 123720631 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 123709944 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 123709728 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 123708138 protein timeless homolog isoform X1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 123710730 TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
C BAG6-UBL4A-GET4 complex
D 123717148 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 123710233 ovarian-specific serine/threonine-protein kinase Lok-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 123716037 14-3-3 protein zeta isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 123709642 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 123707419 protein sickie isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 123717405 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 123714935 plastin-2 K17336 PLS3; plastin-3
D 123708935 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 123714351 vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 123707150 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 123710665 DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 123709635 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D 123714726 three-prime repair exonuclease 1-like K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
C Helicases
C PSO4 complex
D 123708609 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 123712591 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 123717377 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 123713147 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 123711937 oxidized purine nucleoside triphosphate hydrolase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 123713703 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 123714413 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 123718790 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 123714080 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 123714661 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 123715930 single-strand selective monofunctional uracil DNA glycosylase isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 123707757 DNA-3-methyladenine glycosylase 1-like K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 123715043 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 123715043 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 123714413 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024