+E Ubiquitin system KO
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Ubiquitin System - Pituophis catenifer annectens (San Diego gophersnake)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 139322285 UBC; (RefSeq) polyubiquitin-C K08770 UBC; ubiquitin C
C 139317230 UBA52; (RefSeq) ubiquitin-ribosomal protein eL40 fusion protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 139308607 RPS27A; (RefSeq) ubiquitin-ribosomal protein eS31 fusion protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 139324689 NEDD8; (RefSeq) ubiquitin-like protein NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 139311204 ubiquitin-like FUBI-ribosomal protein eS30 fusion protein K02983 RP-S30e; small subunit ribosomal protein S30e
C 139321592 FAU; (RefSeq) ubiquitin-like FUBI-ribosomal protein eS30 fusion protein K02983 RP-S30e; small subunit ribosomal protein S30e
C 139322360 ubiquitin-like protein ISG15 K12159 ISG15; ubiquitin cross-reactive protein
C 139309100 SUMO1; (RefSeq) small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 139312634 SUMO2; (RefSeq) small ubiquitin-related modifier 2 K12160 SUMO; small ubiquitin-related modifier
C 139317922 SUMO3; (RefSeq) small ubiquitin-related modifier 3 isoform X1 K12160 SUMO; small ubiquitin-related modifier
C 139313018 GABARAPL1; (RefSeq) gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 139323522 GABARAPL2; (RefSeq) gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
C 139311309 ATG12; (RefSeq) ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
C 139325708 URM1; (RefSeq) ubiquitin-related modifier 1 isoform X1 K12161 URM1; ubiquitin related modifier 1
C 139316225 UBL3; (RefSeq) ubiquitin-like protein 3 K28515 UBL3; membrane-anchored ubiquitin-fold protein
C 139316557 ZFAND4; (RefSeq) AN1-type zinc finger protein 4 isoform X1 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 139309625 UBA7; (RefSeq) ubiquitin-like modifier-activating enzyme 7 isoform X1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
C 139312875 UBA1; (RefSeq) ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 139320911 SAE1; (RefSeq) SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 139323728 UBA2; (RefSeq) SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 139309469 UBA3; (RefSeq) NEDD8-activating enzyme E1 catalytic subunit isoform X1 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 139323376 NAE1; (RefSeq) NEDD8-activating enzyme E1 regulatory subunit isoform X1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 139315447 MOCS3; (RefSeq) adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 139309568 ATG7; (RefSeq) ubiquitin-like modifier-activating enzyme ATG7 isoform X1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 139322577 UBE2A; (RefSeq) ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 139312476 UBE2B; (RefSeq) ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 139315511 UBE2C; (RefSeq) ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 139314867 UBE2D2; (RefSeq) ubiquitin-conjugating enzyme E2 D2 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 139318410 UBE2D1; (RefSeq) ubiquitin-conjugating enzyme E2 D1 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 139320062 UBE2D3; (RefSeq) ubiquitin-conjugating enzyme E2 D3 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 139319767 UBE2E3; (RefSeq) ubiquitin-conjugating enzyme E2 E3 isoform X1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 139308501 UBE2G1; (RefSeq) ubiquitin-conjugating enzyme E2 G1 isoform X1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 139317921 UBE2G2; (RefSeq) ubiquitin-conjugating enzyme E2 G2 isoform X1 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 139319166 UBE2H; (RefSeq) ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 139308902 UBE2J1; (RefSeq) ubiquitin-conjugating enzyme E2 J1 isoform X1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 139326042 UBE2J2; (RefSeq) ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 139320238 UBE2K; (RefSeq) ubiquitin-conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 139321906 UBE2L3; (RefSeq) ubiquitin-conjugating enzyme E2 L3 isoform X1 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 139327424 ubiquitin-conjugating enzyme E2-18 kDa-like K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 139319929 UBE2N; (RefSeq) ubiquitin-conjugating enzyme E2 N isoform X1 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 139312604 UBE2O; (RefSeq) (E3-independent) E2 ubiquitin-conjugating enzyme isoform X1 K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 139313686 UBE2QL1; (RefSeq) ubiquitin-conjugating enzyme E2Q-like protein 1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 139322358 UBE2Q1; (RefSeq) ubiquitin-conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 139323960 UBE2Q2; (RefSeq) ubiquitin-conjugating enzyme E2 Q2 isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 139313385 UBE2R2; (RefSeq) ubiquitin-conjugating enzyme E2 R2 isoform X1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 139317399 CDC34; (RefSeq) ubiquitin-conjugating enzyme E2 R1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 139317389 UBE2S; (RefSeq) ubiquitin-conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 139314310 UBE2T; (RefSeq) ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 139313991 UBE2U; (RefSeq) ubiquitin-conjugating enzyme E2 U K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 139314704 UBE2W; (RefSeq) ubiquitin-conjugating enzyme E2 W isoform X1 K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 139317391 UBE2Z; (RefSeq) ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 139308719 BIRC6; (RefSeq) dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 139325242 UBE2I; (RefSeq) SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 139309077 UBE2F; (RefSeq) NEDD8-conjugating enzyme UBE2F isoform X1 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 139317468 UBE2M; (RefSeq) NEDD8-conjugating enzyme Ubc12 isoform X1 K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 139316195 ATG3; (RefSeq) ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 139311364 ATG10; (RefSeq) ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 139321693 UFC1; (RefSeq) ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 139316573 UBE3A; (RefSeq) ubiquitin-protein ligase E3A isoform X1 K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 139322278 UBE3B; (RefSeq) ubiquitin-protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 139324604 UBE3D; (RefSeq) E3 ubiquitin-protein ligase E3D K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 139310575 SMURF2; (RefSeq) E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 139325483 SMURF1; (RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 139315412 ITCH; (RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1 K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 139314687 WWP1; (RefSeq) NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 139323686 WWP2; (RefSeq) LOW QUALITY PROTEIN: NEDD4-like E3 ubiquitin-protein ligase WWP2 K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
C 139318522 TRIP12; (RefSeq) E3 ubiquitin-protein ligase TRIP12 isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 139313349 NEDD4L; (RefSeq) E3 ubiquitin-protein ligase NEDD4-like isoform X1 K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 139312910 HUWE1; (RefSeq) E3 ubiquitin-protein ligase HUWE1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 139314864 AREL1; (RefSeq) apoptosis-resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 139314656 UBR5; (RefSeq) E3 ubiquitin-protein ligase UBR5 isoform X1 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 139308000 G2E3; (RefSeq) G2/M phase-specific E3 ubiquitin-protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 139323866 HERC1; (RefSeq) probable E3 ubiquitin-protein ligase HERC1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 139316580 HERC2; (RefSeq) E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 139320753 HERC3; (RefSeq) probable E3 ubiquitin-protein ligase HERC3 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 139318866 HERC4; (RefSeq) probable E3 ubiquitin-protein ligase HERC4 isoform X1 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 139324089 HACE1; (RefSeq) E3 ubiquitin-protein ligase HACE1 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 139327124 HECW2; (RefSeq) E3 ubiquitin-protein ligase HECW2 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 139314613 HECTD1; (RefSeq) E3 ubiquitin-protein ligase HECTD1 isoform X1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 139318003 HECTD2; (RefSeq) probable E3 ubiquitin-protein ligase HECTD2 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 139315258 HECTD3; (RefSeq) E3 ubiquitin-protein ligase HECTD3 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 139321641 HECTD4; (RefSeq) probable E3 ubiquitin-protein ligase HECTD4 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 139312497 NDFIP1; (RefSeq) NEDD4 family-interacting protein 1 isoform X1 K25839 NDFIP; NEDD4 family-interacting protein
D 139316229 NDFIP2; (RefSeq) NEDD4 family-interacting protein 2 isoform X1 K25839 NDFIP; NEDD4 family-interacting protein
D 139309636 N4BP3; (RefSeq) NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
D 139325154 HAPSTR1; (RefSeq) HUWE1-associated protein modifying stress responses 1 K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
B U-box type E3
C 139323268 UBE4A; (RefSeq) ubiquitin conjugation factor E4 A isoform X1 K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 139326182 UBE4B; (RefSeq) LOW QUALITY PROTEIN: ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 139325361 STUB1; (RefSeq) E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 139322252 PPIL2; (RefSeq) RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 139308261 PRPF19; (RefSeq) pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 139327471 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 139325452 RBBP6; (RefSeq) E3 ubiquitin-protein ligase RBBP6 isoform X1 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 139320167 UBOX5; (RefSeq) RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D 139313144 RNF20; (RefSeq) E3 ubiquitin-protein ligase BRE1A isoform X1 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 139321327 CBLC; (RefSeq) E3 ubiquitin-protein ligase CBL-C K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 139323239 CBL; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 139316911 CBLB; (RefSeq) E3 ubiquitin-protein ligase CBL-B K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 139323609 SIAH1; (RefSeq) E3 ubiquitin-protein ligase SIAH1 isoform X1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 139318392 SIAH2; (RefSeq) E3 ubiquitin-protein ligase SIAH2 K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 139316994 LNX2; (RefSeq) ligand of Numb protein X 2 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 139320295 LNX1; (RefSeq) E3 ubiquitin-protein ligase LNX K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 139322637 ligand of Numb protein X 2-like K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 139322673 ligand of Numb protein X 2-like K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 139312245 PDZRN3; (RefSeq) E3 ubiquitin-protein ligase PDZRN3 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 139313728 E3 ubiquitin-protein ligase MARCHF8-like K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 139320404 MARCHF1; (RefSeq) E3 ubiquitin-protein ligase MARCHF1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 139308411 MARCHF2; (RefSeq) E3 ubiquitin-protein ligase MARCHF2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 139311285 MARCHF3; (RefSeq) E3 ubiquitin-protein ligase MARCHF3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 139310715 MARCHF9; (RefSeq) E3 ubiquitin-protein ligase MARCHF9 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 139316034 MARCHF11; (RefSeq) E3 ubiquitin-protein ligase MARCHF11 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 139327313 MARCHF4; (RefSeq) E3 ubiquitin-protein ligase MARCHF4 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 139318412 MARCHF5; (RefSeq) E3 ubiquitin-protein ligase MARCHF5 isoform X1 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 139314846 MARCHF6; (RefSeq) E3 ubiquitin-protein ligase MARCHF6 isoform X1 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 139314308 MARCHF7; (RefSeq) E3 ubiquitin-protein ligase MARCHF7 isoform X1 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 139319236 MDM2; (RefSeq) E3 ubiquitin-protein ligase Mdm2 K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 139315341 MDM4; (RefSeq) protein Mdm4 isoform X1 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 139314847 NFX1; (RefSeq) transcriptional repressor NF-X1 K12236 NFX1; transcriptional repressor NF-X1
D 139320075 NFXL1; (RefSeq) NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 139316138 PELI2; (RefSeq) E3 ubiquitin-protein ligase pellino homolog 2 isoform X1 K11964 PELI; pellino [EC:2.3.2.27]
D 139321812 PELI3; (RefSeq) E3 ubiquitin-protein ligase pellino homolog 3 K11964 PELI; pellino [EC:2.3.2.27]
D 139326601 PELI1; (RefSeq) E3 ubiquitin-protein ligase pellino homolog 1 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 139325971 PEX10; (RefSeq) peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 139318591 PEX12; (RefSeq) peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 139315748 PEX2; (RefSeq) LOW QUALITY PROTEIN: peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 139322339 PRKN; (RefSeq) E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D 139323848 ARIH1; (RefSeq) E3 ubiquitin-protein ligase ARIH1 isoform X1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 139312203 ARIH2; (RefSeq) E3 ubiquitin-protein ligase ARIH2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 139314519 SHARPIN; (RefSeq) sharpin isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 139314582 RBCK1; (RefSeq) LOW QUALITY PROTEIN: ranBP-type and C3HC4-type zinc finger-containing protein 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 139312494 RNF14; (RefSeq) E3 ubiquitin-protein ligase RNF14 isoform X1 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 139314663 RNF19A; (RefSeq) E3 ubiquitin-protein ligase RNF19A isoform X1 K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 139308559 E3 ubiquitin-protein ligase RNF19A-like isoform X1 K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 139321508 RNF19B; (RefSeq) E3 ubiquitin-protein ligase RNF19B K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 139324758 RNF31; (RefSeq) E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 139318611 RFFL; (RefSeq) E3 ubiquitin-protein ligase rififylin K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 139322003 RNF34; (RefSeq) E3 ubiquitin-protein ligase RNF34 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 139314784 RNF144B; (RefSeq) E3 ubiquitin-protein ligase RNF144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 139325402 RNF144A; (RefSeq) E3 ubiquitin-protein ligase RNF144A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 139317925 RNF168; (RefSeq) E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 139316356 RNF169; (RefSeq) E3 ubiquitin-protein ligase RNF169 isoform X1 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 139325831 RNF183; (RefSeq) E3 ubiquitin-protein ligase RNF183 K22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]
D 139325134 RNF216; (RefSeq) E3 ubiquitin-protein ligase RNF216 isoform X1 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 139323455 RNF217; (RefSeq) E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 139309345 TNF receptor-associated factor 2-like K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 139325827 TRAF2; (RefSeq) TNF receptor-associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 139308665 TRAF5; (RefSeq) TNF receptor-associated factor 5 K09849 TRAF5; TNF receptor-associated factor 5
D 139307859 TRAF6; (RefSeq) TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 139325230 TRAF7; (RefSeq) E3 ubiquitin-protein ligase TRAF7 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 139322595 MID2; (RefSeq) probable E3 ubiquitin-protein ligase MID2 isoform X1 K10647 TRIM1; midline 2 [EC:2.3.2.27]
D 139316392 TRIM3; (RefSeq) tripartite motif-containing protein 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 139320640 TRIM2; (RefSeq) tripartite motif-containing protein 2 isoform X1 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 139312160 E3 ubiquitin-protein ligase TRIM7-like K12000 TRIM7; tripartite motif-containing protein 7
D 139318369 TRIM8; (RefSeq) E3 ubiquitin-protein ligase TRIM8 K12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
D 139308208 TRIM9; (RefSeq) E3 ubiquitin-protein ligase TRIM9 isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 139322082 TRIM67; (RefSeq) tripartite motif-containing protein 67 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 139327052 TRIM13; (RefSeq) E3 ubiquitin-protein ligase TRIM13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 139310386 TRIM16; (RefSeq) tripartite motif-containing protein 16 K12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]
D 139316297 MID1; (RefSeq) E3 ubiquitin-protein ligase Midline-1 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 139313309 TRIM23; (RefSeq) E3 ubiquitin-protein ligase TRIM23 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 139319307 TRIM24; (RefSeq) transcription intermediary factor 1-alpha K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 139310470 E3 ubiquitin/ISG15 ligase TRIM25-like K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 139312746 E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 139312748 E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 139323104 TRIM29; (RefSeq) tripartite motif-containing protein 29 K12010 TRIM29; tripartite motif-containing protein 29
D 139315367 TRIM33; (RefSeq) E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 139311314 TRIM36; (RefSeq) E3 ubiquitin-protein ligase TRIM36 isoform X1 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 139308462 TRIM37; (RefSeq) E3 ubiquitin-protein ligase TRIM37 isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 139312081 E3 ubiquitin-protein ligase TRIM39-like K12015 TRIM39; tripartite motif-containing protein 39 / bloodthirsty-related gene family protein [EC:2.3.2.27]
D 139312141 TRIM39; (RefSeq) E3 ubiquitin-protein ligase TRIM39 K12015 TRIM39; tripartite motif-containing protein 39 / bloodthirsty-related gene family protein [EC:2.3.2.27]
D 139312143 TRIM41; (RefSeq) E3 ubiquitin-protein ligase TRIM41 K12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
D 139318529 TRIM42; (RefSeq) tripartite motif-containing protein 42 K12018 TRIM42; tripartite motif-containing protein 42
D 139321768 TRIM46; (RefSeq) tripartite motif-containing protein 46 isoform X1 K12022 TRIM46; tripartite motif-containing protein 46
D 139312619 TRIM47; (RefSeq) E3 ubiquitin-protein ligase TRIM47 K12023 TRIM47; tripartite motif-containing protein 47
D 139308446 TRIM50; (RefSeq) E3 ubiquitin-protein ligase TRIM50 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 139308566 TRIM54; (RefSeq) tripartite motif-containing protein 54 K10653 TRIM54; tripartite motif-containing protein 54
D 139314713 TRIM55; (RefSeq) tripartite motif-containing protein 55 isoform X1 K10654 TRIM55; tripartite motif-containing protein 55
D 139315110 tripartite motif-containing protein 54-like K10654 TRIM55; tripartite motif-containing protein 55
D 139324899 TRIM56; (RefSeq) E3 ubiquitin-protein ligase TRIM56 K12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
D 139310777 E3 ubiquitin-protein ligase TRIM58-like K12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
D 139318229 TRIM59; (RefSeq) tripartite motif-containing protein 59 K12028 TRIM59; tripartite motif-containing protein 59
D 139325943 ERMAP; (RefSeq) erythroid membrane-associated protein K12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
D 139320896 TRIM63; (RefSeq) E3 ubiquitin-protein ligase TRIM63 K10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]
D 139312617 TRIM65; (RefSeq) E3 ubiquitin-protein ligase TRIM65 K12031 TRIM65; tripartite motif-containing protein 65
D 139310904 TRIM66; (RefSeq) tripartite motif-containing protein 66 K12032 TRIM66; tripartite motif-containing protein 66
D 139323895 TRIM69; (RefSeq) E3 ubiquitin-protein ligase TRIM69 K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
D 139326892 zinc-binding protein A33-like K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
C UBR box proteins
D 139314254 UBR1; (RefSeq) E3 ubiquitin-protein ligase UBR1 K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D 139308662 UBR2; (RefSeq) E3 ubiquitin-protein ligase UBR2 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 139312409 UBR3; (RefSeq) E3 ubiquitin-protein ligase UBR3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 139326060 UBR4; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR4 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 139315296 UBR7; (RefSeq) putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 139323535 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 139318075 AIRE; (RefSeq) autoimmune regulator K10603 AIRE; autoimmune regulator
D 139325161 BFAR; (RefSeq) bifunctional apoptosis regulator K15684 BFAR; bifunctional apoptosis regulator
D 139316266 putative inhibitor of apoptosis K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 139322692 XIAP; (RefSeq) E3 ubiquitin-protein ligase XIAP K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 139315470 BIRC7; (RefSeq) baculoviral IAP repeat-containing protein 7 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 139319003 CBLL1; (RefSeq) E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 139321669 CHFR; (RefSeq) E3 ubiquitin-protein ligase CHFR isoform X1 K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 139319121 CNOT4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 139321533 DCST1; (RefSeq) E3 ubiquitin-protein ligase DCST1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 139308516 DTX2; (RefSeq) probable E3 ubiquitin-protein ligase DTX2 isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 139310760 DTX3; (RefSeq) LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase DTX3 K06058 DTX; deltex [EC:2.3.2.27]
D 139320250 DTX3L; (RefSeq) E3 ubiquitin-protein ligase DTX3L K06058 DTX; deltex [EC:2.3.2.27]
D 139326939 DTX1; (RefSeq) E3 ubiquitin-protein ligase DTX1 K06058 DTX; deltex [EC:2.3.2.27]
D 139327439 DTX4; (RefSeq) E3 ubiquitin-protein ligase DTX4 K06058 DTX; deltex [EC:2.3.2.27]
D 139319593 FANCL; (RefSeq) E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 139313134 KCMF1; (RefSeq) E3 ubiquitin-protein ligase KCMF1 isoform X1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 139325569 LRSAM1; (RefSeq) E3 ubiquitin-protein ligase LRSAM1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 139316120 LTN1; (RefSeq) E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 139311442 MAP3K1; (RefSeq) mitogen-activated protein kinase kinase kinase 1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 139308291 MEX3D; (RefSeq) RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 139313357 MEX3C; (RefSeq) RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 139322096 MEX3A; (RefSeq) RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 139324039 MEX3B; (RefSeq) LOW QUALITY PROTEIN: RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 139325110 MGRN1; (RefSeq) E3 ubiquitin-protein ligase MGRN1 isoform X1 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 139314750 MIB1; (RefSeq) E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 139325911 MIB2; (RefSeq) E3 ubiquitin-protein ligase MIB2 isoform X1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 139312308 MKRN2; (RefSeq) E3 ubiquitin-protein ligase makorin-2 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 139314174 probable E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 139319373 MKRN1; (RefSeq) E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 139317955 mitochondrial ubiquitin ligase activator of nfkb 1-A-like K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 139325930 MUL1; (RefSeq) mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 139317206 MYCBP2; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYCBP2 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 139314794 MYLIP; (RefSeq) E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 139309757 NEURL1B; (RefSeq) E3 ubiquitin-protein ligase NEURL1B K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 139318436 NEURL1; (RefSeq) E3 ubiquitin-protein ligase NEURL1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 139315963 NHLRC1; (RefSeq) E3 ubiquitin-protein ligase NHLRC1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 139316403 OBI1; (RefSeq) ORC ubiquitin ligase 1 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 139313246 PJA2; (RefSeq) E3 ubiquitin-protein ligase Praja-2 isoform X1 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 139309499 RAD18; (RefSeq) E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 139307860 RAG1; (RefSeq) V(D)J recombination-activating protein 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 139313772 RC3H1; (RefSeq) roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 139325894 RC3H2; (RefSeq) roquin-2 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 139313777 COP1; (RefSeq) E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 139323589 RFWD3; (RefSeq) E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 139311709 RING1; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RING1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 139314941 RNF2; (RefSeq) E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 139314715 E3 ubiquitin-protein ligase RNF4-like K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 139312069 RNF5; (RefSeq) E3 ubiquitin-protein ligase RNF5 isoform X1 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 139322037 RNF185; (RefSeq) E3 ubiquitin-protein ligase RNF185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 139317002 RNF6; (RefSeq) E3 ubiquitin-protein ligase RNF6 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 139321263 RNF8; (RefSeq) E3 ubiquitin-protein ligase RNF8 isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 139322442 RNF10; (RefSeq) E3 ubiquitin-protein ligase RNF10 isoform X1 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 139312525 RING finger protein 11-like K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 139315242 RNF11; (RefSeq) RING finger protein 11 isoform X1 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 139322668 RLIM; (RefSeq) E3 ubiquitin-protein ligase RLIM K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 139308373 E3 ubiquitin-protein ligase RNF167-like K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 139318649 RNF13; (RefSeq) E3 ubiquitin-protein ligase RNF13 isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 139324877 RNF25; (RefSeq) E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 139323131 RNF26; (RefSeq) E3 ubiquitin-protein ligase RNF26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 139309653 RNF44; (RefSeq) RING finger protein 44 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 139313124 RNF38; (RefSeq) E3 ubiquitin-protein ligase RNF38 isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 139310676 RNF41; (RefSeq) E3 ubiquitin-protein ligase NRDP1 isoform X1 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 139318739 RNF43; (RefSeq) E3 ubiquitin-protein ligase RNF43 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 139324064 RNF111; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Arkadia K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 139314424 RNF114; (RefSeq) E3 ubiquitin-protein ligase RNF114 K15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
D 139308275 RNF126; (RefSeq) E3 ubiquitin-protein ligase RNF126 isoform X1 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 139321701 RNF115; (RefSeq) E3 ubiquitin-protein ligase RNF115 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 139317172 RNF121; (RefSeq) E3 ubiquitin ligase RNF121 K15698 RNF121_175; RING finger protein 121/175
D 139323144 RNF122; (RefSeq) RING finger protein 122 isoform X1 K15699 RNF122; RING finger protein 122
D 139312377 RNF123; (RefSeq) E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 139315845 RNF125; (RefSeq) E3 ubiquitin-protein ligase RNF125 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 139322785 RNF128; (RefSeq) E3 ubiquitin-protein ligase RNF128 isoform X1 K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 139326928 E3 ubiquitin-protein ligase RNF128-like K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 139312443 RNF130; (RefSeq) E3 ubiquitin-protein ligase RNF130 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 139310615 E3 ubiquitin-protein ligase RNF135-like K16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]
D 139315843 RNF138; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF138 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 139315632 RNF139; (RefSeq) E3 ubiquitin-protein ligase RNF139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 139312416 RNF145; (RefSeq) RING finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 139320226 RING finger protein 145-like isoform X1 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 139323393 RNF146; (RefSeq) E3 ubiquitin-protein ligase RNF146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 139316551 RNF149; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF149 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 139316022 RNF152; (RefSeq) E3 ubiquitin-protein ligase RNF152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 139312612 RNF157; (RefSeq) E3 ubiquitin ligase RNF157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 139323650 RNF166; (RefSeq) E3 ubiquitin-protein ligase RNF166 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 139324929 RNF167; (RefSeq) E3 ubiquitin-protein ligase RNF167 K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 139311119 RNF170; (RefSeq) E3 ubiquitin-protein ligase RNF170 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 139315207 E3 ubiquitin-protein ligase RNF170-like K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 139311429 RNF180; (RefSeq) E3 ubiquitin-protein ligase RNF180 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 139315536 E3 ubiquitin-protein ligase RNF182-like K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 139315967 RNF182; (RefSeq) E3 ubiquitin-protein ligase RNF182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 139323676 E3 ubiquitin-protein ligase RNF182-like K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 139326166 RNF186; (RefSeq) E3 ubiquitin-protein ligase RNF186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 139312688 RNF213; (RefSeq) E3 ubiquitin-protein ligase RNF213 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 139315266 RNF220; (RefSeq) E3 ubiquitin-protein ligase RNF220 isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 139317920 RNFT1; (RefSeq) E3 ubiquitin-protein ligase RNFT1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 139322005 RNFT2; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNFT2 K28516 RNFT2; E3 ubiquitin-protein ligase RNFT2
D 139322283 SART1; (RefSeq) U4/U6.U5 tri-snRNP-associated protein 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 139308808 SHPRH; (RefSeq) E3 ubiquitin-protein ligase SHPRH isoform X1 K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 139309739 SH3RF2; (RefSeq) E3 ubiquitin-protein ligase SH3RF2 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 139316451 SH3RF3; (RefSeq) E3 ubiquitin-protein ligase SH3RF3 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 139320321 SH3RF1; (RefSeq) E3 ubiquitin-protein ligase SH3RF1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 139317799 HLTF; (RefSeq) helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 139321845 SYVN1; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase synoviolin K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 139311150 TOPORS; (RefSeq) E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 139309620 TRAIP; (RefSeq) E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 139317271 TTC3; (RefSeq) E3 ubiquitin-protein ligase TTC3 isoform X1 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 139308374 UHRF1; (RefSeq) E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 139313173 UHRF2; (RefSeq) E3 ubiquitin-protein ligase UHRF2 isoform X1 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 139325155 ZNF598; (RefSeq) E3 ubiquitin-protein ligase ZNF598 isoform X1 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 139308011 ZFP91; (RefSeq) E3 ubiquitin-protein ligase ZFP91 K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 139323424 ZNRF1; (RefSeq) E3 ubiquitin-protein ligase ZNRF1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 139321917 ZNRF3; (RefSeq) E3 ubiquitin-protein ligase ZNRF3 isoform X1 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 139308372 E3 ubiquitin-protein ligase RNF167-like K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
D 139327148 ZSWIM2; (RefSeq) E3 ubiquitin-protein ligase ZSWIM2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C 139312473 JADE2; (RefSeq) E3 ubiquitin-protein ligase Jade-2 isoform X1 K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
C 139325190 E4F1; (RefSeq) transcription factor E4F1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 139325514 NSMCE1; (RefSeq) non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 139315016 IRF2BPL; (RefSeq) probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
C 139321075 IRF2BP1; (RefSeq) interferon regulatory factor 2-binding protein 1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 139311150 TOPORS; (RefSeq) E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 139316492 RGPD4; (RefSeq) ranBP2-like and GRIP domain-containing protein 4 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 139324221 PIAS1; (RefSeq) E3 SUMO-protein ligase PIAS1 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 139313369 PIAS2; (RefSeq) E3 SUMO-protein ligase PIAS2 isoform X1 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 139322292 LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS3-like K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 139317604 PIAS4; (RefSeq) E3 SUMO-protein ligase PIAS4 isoform X1 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 139323968 protein PML-like K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 139324100 protein PML-like K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 139312683 CBX4; (RefSeq) E3 SUMO-protein ligase CBX4 K11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
C 139315627 NSMCE2; (RefSeq) E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 139321519 RNF212; (RefSeq) probable E3 SUMO-protein ligase RNF212 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 139324760 RNF212B; (RefSeq) E3 ubiquitin-protein ligase RNF212B K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 139316469 ZBED1; (RefSeq) E3 SUMO-protein ligase ZBED1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 139321233 E3 SUMO-protein ligase ZBED1-like K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 139308939 ZNF451; (RefSeq) E3 SUMO-protein ligase ZNF451 isoform X1 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 139320252 probable E3 ubiquitin-protein ligase HERC6 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 139320253 probable E3 ubiquitin-protein ligase HERC6 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 139320257 E3 ISG15--protein ligase HERC5-like K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 139308895 UFL1; (RefSeq) E3 UFM1-protein ligase 1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 139316561 DCUN1D2; (RefSeq) DCN1-like protein 2 isoform X1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 139318140 DCUN1D1; (RefSeq) DCN1-like protein 1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 139325247 DCUN1D3; (RefSeq) DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 139316262 DCUN1D5; (RefSeq) DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 139320364 DCUN1D4; (RefSeq) DCN1-like protein 4 isoform X1 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit type E3
C SCF complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 139312479 SKP1; (RefSeq) S-phase kinase-associated protein 1 isoform X1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 139308997 FBXW11; (RefSeq) F-box/WD repeat-containing protein 11 isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 139318046 BTRC; (RefSeq) F-box/WD repeat-containing protein 1A isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 139325753 FBXW2; (RefSeq) F-box/WD repeat-containing protein 2 isoform X1 K10261 FBXW2; F-box and WD-40 domain protein 2
E 139318679 FBXW4; (RefSeq) F-box/WD repeat-containing protein 4 isoform X1 K10262 FBXW4; F-box and WD-40 domain protein 4
E 139325825 FBXW5; (RefSeq) F-box/WD repeat-containing protein 5 isoform X1 K10263 FBXW5; F-box and WD-40 domain protein 5
E 139316396 F-box/WD repeat-containing protein 7-like isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 139320418 FBXW7; (RefSeq) F-box/WD repeat-containing protein 7 isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 139322111 FBXW8; (RefSeq) LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 139312527 FBXW9; (RefSeq) F-box/WD repeat-containing protein 9 K10265 FBXW9; F-box and WD-40 domain protein 9
E 139310361 FBXW10B; (RefSeq) F-box and WD repeat domain containing protein 10B K10266 FBXW10; F-box and WD-40 domain protein 10
E 139309556 FBXW12; (RefSeq) F-box/WD repeat-containing protein 12 isoform X1 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 139311496 SKP2; (RefSeq) S-phase kinase-associated protein 2 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 139316236 FBXL3; (RefSeq) F-box/LRR-repeat protein 3 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 139324122 FBXL4; (RefSeq) F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 139320539 FBXL5; (RefSeq) F-box/LRR-repeat protein 5 isoform X1 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 139314523 FBXL6; (RefSeq) LOW QUALITY PROTEIN: F-box/LRR-repeat protein 6 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 139316035 FBXL7; (RefSeq) F-box/LRR-repeat protein 7 isoform X1 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 139323620 F-box/LRR-repeat protein 8-like K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 139323727 F-box/LRR-repeat protein 8-like K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 139323536 uncharacterized protein isoform X1 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 139321580 KDM2B; (RefSeq) lysine-specific demethylase 2B isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 139327432 KDM2A; (RefSeq) lysine-specific demethylase 2A isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 139312865 FBXL12; (RefSeq) F-box/LRR-repeat protein 12 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 139319490 FBXL13; (RefSeq) F-box and leucine-rich repeat protein 13 K10279 FBXL13; dynein regulatory complex subunit 6
E 139319493 FBXL14; (RefSeq) F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 139318515 FBXL15; (RefSeq) F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 139325384 FBXL16; (RefSeq) F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 139311327 FBXL17; (RefSeq) F-box/LRR-repeat protein 17 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 139325159 FBXL18; (RefSeq) F-box/LRR-repeat protein 18 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 139317364 FBXL19; (RefSeq) F-box/LRR-repeat protein 19 K10285 FBXL19; F-box and leucine-rich repeat protein 19
E 139312467 F-box/LRR-repeat protein 21-like K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 139323864 FBXL22; (RefSeq) F-box and leucine-rich protein 22 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 139325276 CCNF; (RefSeq) cyclin-F K10289 CCNF; F-box protein 1 (cyclin F)
E 139326165 FBXO2; (RefSeq) LOW QUALITY PROTEIN: F-box only protein 2 K10099 FBXO2; F-box protein 2
E 139326258 LOW QUALITY PROTEIN: F-box only protein 2-like K10099 FBXO2; F-box protein 2
E 139311117 FBXO3; (RefSeq) F-box only protein 3 isoform X1 K10290 FBXO3; F-box protein 3
E 139311476 FBXO4; (RefSeq) F-box only protein 4 K10291 FBXO4; F-box protein 4
E 139322611 FBXO5; (RefSeq) F-box only protein 5 K10292 FBXO5; F-box protein 5
E 139325986 F-box only protein 6-like K10100 FBXO6; F-box protein 6
E 139326006 F-box only protein 44-like isoform X1 K10100 FBXO6; F-box protein 6
E 139326099 F-box only protein 44-like K10100 FBXO6; F-box protein 6
E 139326243 F-box only protein 6-like K10100 FBXO6; F-box protein 6
E 139319936 FBXO7; (RefSeq) F-box only protein 7 isoform X1 K10293 FBXO7; F-box protein 7
E 139320453 FBXO8; (RefSeq) F-box only protein 8 isoform X1 K10294 FBXO8; F-box protein 8
E 139308945 FBXO9; (RefSeq) F-box only protein 9 isoform X1 K10295 FBXO9; F-box protein 9
E 139311092 FBXO10; (RefSeq) F-box only protein 10 K10296 FBXO10; F-box protein 10
E 139308617 FBXO11; (RefSeq) F-box only protein 11 isoform X1 K10297 FBXO11; F-box protein 11
E 139315918 FBXO15; (RefSeq) F-box only protein 15 K10298 FBXO15; F-box protein 15
E 139319312 FBXO16; (RefSeq) F-box only protein 16 K10299 FBXO16; F-box protein 16
E 139319656 F-box DNA helicase 1-like K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 139319657 F-box DNA helicase 1-like K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 139317198 LMO7; (RefSeq) LIM domain only protein 7 isoform X1 K06084 LMO7; F-box protein 20
E 139321794 FBXO21; (RefSeq) F-box only protein 21 isoform X1 K10301 FBXO21; F-box protein 21
E 139323998 FBXO22; (RefSeq) F-box only protein 22 K10302 FBXO22; F-box protein 22
E 139309649 TSPAN17; (RefSeq) tetraspanin-17 isoform X1 K10303 FBXO23; F-box protein 23
E 139324909 FBXO24; (RefSeq) F-box only protein 24 K10304 FBXO24; F-box protein 24
E 139308953 FBXO25; (RefSeq) F-box only protein 25 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 139314632 FBXO32; (RefSeq) F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 139321488 F-box only protein 27-like isoform X1 K10102 FBXO27; F-box protein 27
E 139320875 FBXO28; (RefSeq) F-box only protein 28 K10306 FBXO28; F-box protein 28
E 139308809 FBXO30; (RefSeq) F-box only protein 30 K10307 FBXO30; F-box protein 30
E 139323443 FBXO31; (RefSeq) F-box only protein 31 isoform X1 K10308 FBXO31; F-box protein 31
E 139314769 FBXO33; (RefSeq) F-box only protein 33 K10310 FBXO33; F-box protein 33
E 139308189 FBXO34; (RefSeq) F-box only protein 34 K10311 FBXO34; F-box protein 34
E 139317201 F-box only protein 36-like K10312 FBXO36; F-box protein 36
E 139318523 FBXO36; (RefSeq) F-box only protein 36 K10312 FBXO36; F-box protein 36
E 139312516 FBXO38; (RefSeq) F-box only protein 38 K10313 FBXO38; F-box protein 38
E 139313049 FBXO40; (RefSeq) F-box only protein 40 isoform X1 K10315 FBXO40; F-box protein 40
E 139320563 FBXO41; (RefSeq) F-box only protein 41 K10316 FBXO41; F-box protein 41
E 139326035 FBXO42; (RefSeq) F-box only protein 42 K10317 FBXO42; F-box protein 42
E 139315679 FBXO43; (RefSeq) F-box only protein 43 K10318 FBXO43; F-box protein 43
E 139318118 FBXO45; (RefSeq) F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 139321419 FBXO46; (RefSeq) F-box only protein 46 K10320 FBXO46; F-box protein 46
E 139309012 FBXO48; (RefSeq) F-box only protein 48 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 139317548 CUL2; (RefSeq) cullin-2 isoform X1 K03870 CUL2; cullin 2
D Adoptor protein
E 139315755 ELOC; (RefSeq) elongin-C isoform X1 K03872 ELOC; elongin-C
D Target recognizing subunit
E 139312251 VHL; (RefSeq) von Hippel-Lindau disease tumor suppressor K03871 VHL; von Hippel-Lindau disease tumor supressor
E 139308219 LRR1; (RefSeq) leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 139313237 FEM1C; (RefSeq) protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 139317486 FEM1A; (RefSeq) protein fem-1 homolog A K25805 FEM1A_C; protein fem-1 homolog A/C
E 139324215 FEM1B; (RefSeq) protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 139308464 APPBP2; (RefSeq) amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 139308213 KLHDC2; (RefSeq) kelch domain-containing protein 2 K25807 KLHDC2; kelch domain-containing protein 2
E 139308634 KLHDC3; (RefSeq) kelch domain-containing protein 3 isoform X1 K25808 KLHDC3; kelch domain-containing protein 3
E 139319569 KLHDC10; (RefSeq) kelch domain-containing protein 10 isoform X1 K25809 KLHDC10; kelch domain-containing protein 10
E 139315227 protein zyg-11 homolog B-like isoform X1 K10350 ZYG11; Zyg-11 protein
E 139315228 protein zyg-11 homolog B isoform X1 K10350 ZYG11; Zyg-11 protein
E 139325762 ZER1; (RefSeq) protein zer-1 homolog K10350 ZYG11; Zyg-11 protein
E 139318860 ZSWIM8; (RefSeq) zinc finger SWIM domain-containing protein 8 isoform X1 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 139318025 CUL3; (RefSeq) cullin-3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 139316206 KLHL1; (RefSeq) kelch-like protein 1 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 139320044 KLHL5; (RefSeq) kelch-like protein 5 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 139322580 KLHL4; (RefSeq) kelch-like protein 4 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 139312464 KLHL3; (RefSeq) kelch-like protein 3 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 139320760 kelch-like protein 2 K10443 KLHL2_3; kelch-like protein 2/3
E 139318115 KLHL6; (RefSeq) kelch-like protein 6 K10444 KLHL6; kelch-like protein 6
E 139320190 KLHL8; (RefSeq) kelch-like protein 8 K10446 KLHL8; kelch-like protein 8
E 139322684 kelch-like protein 13 isoform X1 K10447 KLHL9_13; kelch-like protein 9/13
E 139325769 LOW QUALITY PROTEIN: kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 139325321 KLHL10; (RefSeq) kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 139314324 KLHL12; (RefSeq) kelch-like protein 12 isoform X1 K10450 KLHL12; kelch-like protein 12
E 139315840 KLHL14; (RefSeq) kelch-like protein 14 K10451 KLHL14; kelch-like protein 14
E 139316531 KLHL15; (RefSeq) kelch-like protein 15 isoform X1 K10452 KLHL15; kelch-like protein 15
E 139323768 GAN; (RefSeq) gigaxonin K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 139325968 KLHL17; (RefSeq) LOW QUALITY PROTEIN: kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 139312964 KEAP1; (RefSeq) kelch-like ECH-associated protein 1 K10456 KLHL19; kelch-like protein 19
E 139314917 KLHL20; (RefSeq) kelch-like protein 20 isoform X1 K10457 KLHL20; kelch-like protein 20
E 139325729 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 139326041 KLHL21; (RefSeq) kelch-like protein 21 K10458 KLHL21; kelch-like protein 21
E 139322245 KLHL22; (RefSeq) kelch-like protein 22 K10459 KLHL22; kelch-like protein 22
E 139327193 KLHL23; (RefSeq) kelch-like protein 23 K10460 KLHL23; kelch-like protein 23
E 139317836 KLHL24; (RefSeq) kelch-like protein 24 K10461 KLHL24_35; kelch-like protein 24/35
E 139311390 ENC1; (RefSeq) ectoderm-neural cortex protein 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 139323991 KLHL25; (RefSeq) kelch-like protein 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 139308331 KLHL26; (RefSeq) kelch-like protein 26 isoform X1 K10463 KLHL26; kelch-like protein 26
E 139315252 IPP; (RefSeq) actin-binding protein IPP isoform X1 K13956 IPP; actin-binding protein IPP
E 139316453 KLHL28; (RefSeq) kelch-like protein 28 K10464 KLHL28; kelch-like protein 28
E 139325790 KLHL29; (RefSeq) kelch-like protein 29 K10465 KLHL29; kelch-like protein 29
E 139318524 KLHL30; (RefSeq) kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 139308943 KLHL31; (RefSeq) kelch-like protein 31 isoform X1 K10467 KLHL31; kelch-like protein 31
E 139321215 kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 139324151 KLHL32; (RefSeq) kelch-like protein 32 isoform X1 K10468 KLHL32; kelch-like protein 32
E 139323414 KLHL36; (RefSeq) kelch-like protein 36 K13958 KLHL36; kelch-like protein 36
E 139314631 KLHL38; (RefSeq) kelch-like protein 38 K13959 KLHL38; kelch-like protein 38
E 139319513 KLHL42; (RefSeq) kelch-like protein 42 K27973 KLHL42; kelch-like protein 42
E 139317044 KBTBD3; (RefSeq) kelch repeat and BTB domain-containing protein 3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 139312276 KBTBD4; (RefSeq) kelch repeat and BTB domain-containing protein 4 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 139312866 KLHL41; (RefSeq) kelch-like protein 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 139309463 KBTBD8; (RefSeq) LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 8 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 139325182 KBTBD11; (RefSeq) kelch repeat and BTB domain-containing protein 11 K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E 139312274 KBTBD12; (RefSeq) kelch repeat and BTB domain-containing protein 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 139324078 KBTBD13; (RefSeq) kelch repeat and BTB domain-containing protein 13 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 139316919 BTBD2; (RefSeq) BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 139324199 BTBD1; (RefSeq) LOW QUALITY PROTEIN: BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 139315855 BTBD6; (RefSeq) BTB/POZ domain-containing protein 6 isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 139326246 BTBD3; (RefSeq) BTB/POZ domain-containing protein 3 isoform X1 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 139308089 BTBD7; (RefSeq) BTB/POZ domain-containing protein 7 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 139313911 BTBD8; (RefSeq) BTB/POZ domain-containing protein 8 K10480 BTBD8; BTB/POZ domain-containing protein 8
E 139321234 BTBD9; (RefSeq) BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 139310126 BTBD10; (RefSeq) BTB/POZ domain-containing protein 10 isoform X1 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 139319775 ABTB3; (RefSeq) ankyrin repeat and BTB/POZ domain-containing protein 3 isoform X1 K10483 BTBD11; BTB/POZ domain-containing protein 11
E 139310204 NACC1; (RefSeq) nucleus accumbens-associated protein 1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 139325666 NACC2; (RefSeq) nucleus accumbens-associated protein 2 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 139318507 BTBD16; (RefSeq) BTB/POZ domain-containing protein 16 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 139315892 ZBTB1; (RefSeq) zinc finger and BTB domain-containing protein 1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 139322664 ZBTB2; (RefSeq) zinc finger and BTB domain-containing protein 2 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 139321621 ZBTB3; (RefSeq) zinc finger and BTB domain-containing protein 3 K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E 139311094 ZBTB5; (RefSeq) zinc finger and BTB domain-containing protein 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 139325678 ZBTB6; (RefSeq) zinc finger and BTB domain-containing protein 6 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 139311541 ZBTB7C; (RefSeq) zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 139317595 ZBTB7A; (RefSeq) zinc finger and BTB domain-containing protein 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 139320878 ZBTB8B; (RefSeq) zinc finger and BTB domain-containing protein 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 139320879 ZBTB8A; (RefSeq) zinc finger and BTB domain-containing protein 8A isoform X1 K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 139311729 ZBTB9; (RefSeq) zinc finger and BTB domain-containing protein 9 K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E 139314696 ZBTB10; (RefSeq) zinc finger and BTB domain-containing protein 10 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 139316179 ZBTB11; (RefSeq) zinc finger and BTB domain-containing protein 11 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 139312097 ZBTB12; (RefSeq) zinc finger and BTB domain-containing protein 12 isoform X1 K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E 139323314 ZBTB16; (RefSeq) zinc finger and BTB domain-containing protein 16 K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
E 139326186 ZBTB17; (RefSeq) zinc finger and BTB domain-containing protein 17 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 139316957 ZBTB20; (RefSeq) zinc finger and BTB domain-containing protein 20 K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
E 139311721 ZBTB22; (RefSeq) LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 22 K10502 ZBTB22; zinc finger and BTB domain-containing protein 22
E 139308880 ZBTB24; (RefSeq) zinc finger and BTB domain-containing protein 24 isoform X1 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 139315908 ZBTB25; (RefSeq) zinc finger and BTB domain-containing protein 25 isoform X1 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 139321280 zinc finger and BTB domain-containing protein 26-like K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 139325778 ZBTB26; (RefSeq) zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 139322536 ZBTB33; (RefSeq) transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 139313771 ZBTB37; (RefSeq) zinc finger and BTB domain-containing protein 37 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 139318416 ZBTB38; (RefSeq) zinc finger and BTB domain-containing protein 38 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 139324263 ZBTB4; (RefSeq) zinc finger and BTB domain-containing protein 4 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 139310691 ZBTB39; (RefSeq) zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 139313836 ZBTB41; (RefSeq) zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 139325730 ZBTB43; (RefSeq) zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 139323322 ZBTB44; (RefSeq) zinc finger and BTB domain-containing protein 44 isoform X1 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 139315481 ZBTB46; (RefSeq) zinc finger and BTB domain-containing protein 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 139325928 ZBTB48; (RefSeq) telomere zinc finger-associated protein isoform X1 K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 139312273 ABTB1; (RefSeq) ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 139311199 ABTB2; (RefSeq) ankyrin repeat and BTB/POZ domain-containing protein 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 139318195 RHOBTB1; (RefSeq) rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 139320058 rho-related BTB domain-containing protein 1-like isoform X1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 139323069 RHOBTB2; (RefSeq) rho-related BTB domain-containing protein 2 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 139310382 RHOBTB3; (RefSeq) rho-related BTB domain-containing protein 3 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 139317363 KCTD13; (RefSeq) BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 139318165 TNFAIP1; (RefSeq) BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 139321908 KCTD10; (RefSeq) BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 139315854 KCTD1; (RefSeq) BTB/POZ domain-containing protein KCTD1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 139323454 KCTD15; (RefSeq) BTB/POZ domain-containing protein KCTD15 isoform X1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 139312638 KCTD2; (RefSeq) BTB/POZ domain-containing protein KCTD2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 139319397 KCTD17; (RefSeq) BTB/POZ domain-containing protein KCTD17 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 139325241 KCTD5; (RefSeq) BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 139308670 KCTD3; (RefSeq) BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 139312229 KCTD6; (RefSeq) BTB/POZ domain-containing protein KCTD6 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 139317123 KCTD14; (RefSeq) BTB/POZ domain-containing protein KCTD14 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 139309736 KCTD16; (RefSeq) BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 139316486 KCTD12; (RefSeq) BTB/POZ domain-containing protein KCTD12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 139320119 KCTD8; (RefSeq) BTB/POZ domain-containing protein KCTD8 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 139322599 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 139323205 KCTD9; (RefSeq) BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 139324934 KCTD11; (RefSeq) BTB/POZ domain-containing protein KCTD11 K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 139327113 KCTD18; (RefSeq) BTB/POZ domain-containing protein KCTD18 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 139317118 KCTD21; (RefSeq) BTB/POZ domain-containing protein KCTD21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 139321734 DIABLO; (RefSeq) diablo IAP-binding mitochondrial protein K10522 DIABLO; diablo
E 139318801 SPOPL; (RefSeq) speckle-type POZ protein-like isoform X1 K10523 SPOP; speckle-type POZ protein
E 139315383 LZTR1; (RefSeq) leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 139322888 CUL4B; (RefSeq) cullin-4B K10609 CUL4; cullin 4
D Adoptor protein
E 139308329 DDB1; (RefSeq) DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 139312074 DDB2; (RefSeq) DNA damage-binding protein 2 K10140 DDB2; DNA damage-binding protein 2
E 139311436 ERCC8; (RefSeq) DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8
E 139324046 DET1; (RefSeq) DET1 homolog isoform X1 K10571 DET1; de-etiolated-1
E 139313777 COP1; (RefSeq) E3 ubiquitin-protein ligase COP1 isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 139316716 DDA1; (RefSeq) DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 139312248 CRBN; (RefSeq) protein cereblon isoform X1 K11793 CRBN; cereblon
E 139315405 TRPC4AP; (RefSeq) short transient receptor potential channel 4-associated protein K11796 TRPC4AP; Trpc4-associated protein
E 139312356 DCAF1; (RefSeq) DDB1- and CUL4-associated factor 1 isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 139320430 DTL; (RefSeq) LOW QUALITY PROTEIN: denticleless protein homolog K11790 DTL; denticleless
E 139314087 DCAF4; (RefSeq) DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 139313232 DCAF5; (RefSeq) DDB1- and CUL4-associated factor 5 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 139316154 DCAF6; (RefSeq) DDB1- and CUL4-associated factor 6 isoform X1 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 139317462 DCAF7; (RefSeq) DDB1- and CUL4-associated factor 7 isoform X1 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 139322166 DCAF8; (RefSeq) DDB1- and CUL4-associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 139321462 WDTC1; (RefSeq) WD and tetratricopeptide repeats protein 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 139313122 DCAF10; (RefSeq) DDB1- and CUL4-associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 139324742 DCAF11; (RefSeq) DDB1- and CUL4-associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 139311564 DCAF12; (RefSeq) DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 139315666 DCAF13; (RefSeq) DDB1- and CUL4-associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 139308922 PHIP; (RefSeq) PH-interacting protein isoform X1 K11797 PHIP; PH-interacting protein
E 139312969 DCAF15; (RefSeq) DDB1- and CUL4-associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 139327187 DCAF17; (RefSeq) DDB1- and CUL4-associated factor 17 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 139317269 BRWD1; (RefSeq) bromodomain and WD repeat-containing protein 1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 139322539 BRWD3; (RefSeq) bromodomain and WD repeat-containing protein 3 isoform X1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 139308678 WDR26; (RefSeq) WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
E 139311493 WDR70; (RefSeq) WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 139323846 WDR76; (RefSeq) WD repeat-containing protein 76 isoform X1 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 139317975 RNF7; (RefSeq) RING-box protein 2 isoform X1 K10611 RBX2; RING-box protein 2
D Cullin
E 139316255 CUL5; (RefSeq) cullin-5 isoform X1 K10612 CUL5; cullin 5
D Adoptor protein
E 139315755 ELOC; (RefSeq) elongin-C isoform X1 K03872 ELOC; elongin-C
D Target recognizing subunit
E 139309596 CISH; (RefSeq) cytokine-inducible SH2-containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 139325277 SOCS1; (RefSeq) suppressor of cytokine signaling 1 K04694 SOCS1; suppressor of cytokine signaling 1
E 139319928 SOCS2; (RefSeq) suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 139312677 SOCS3; (RefSeq) suppressor of cytokine signaling 3 K04696 SOCS3; suppressor of cytokine signaling 3
E 139308191 SOCS4; (RefSeq) suppressor of cytokine signaling 4 isoform X1 K04697 SOCS4; suppressor of cytokine signaling 4
E 139320093 SOCS5; (RefSeq) suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 139320818 suppressor of cytokine signaling 5-like K04698 SOCS5; suppressor of cytokine signaling 5
E 139315916 SOCS6; (RefSeq) suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 139315313 ASB2; (RefSeq) ankyrin repeat and SOCS box protein 2 K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 139319695 ASB3; (RefSeq) ankyrin repeat and SOCS box protein 3 K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 139320193 ASB5; (RefSeq) ankyrin repeat and SOCS box protein 5 isoform X1 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 139325785 ASB6; (RefSeq) ankyrin repeat and SOCS box protein 6 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 139323918 ASB7; (RefSeq) ankyrin repeat and SOCS box protein 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 139312837 ASB8; (RefSeq) ankyrin repeat and SOCS box protein 8 K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 139316450 ankyrin repeat and SOCS box protein 9-like K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 139317472 ASB10; (RefSeq) LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 10 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 139322920 ASB12; (RefSeq) ankyrin repeat and SOCS box protein 12 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 139319359 ASB13; (RefSeq) ankyrin repeat and SOCS box protein 13 isoform X1 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 139312291 ASB14; (RefSeq) ankyrin repeat and SOCS box protein 14 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 139319074 ASB15; (RefSeq) ankyrin repeat and SOCS box protein 15 isoform X1 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 139308487 WSB1; (RefSeq) WD repeat and SOCS box-containing protein 1 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 139321998 WSB2; (RefSeq) WD repeat and SOCS box-containing protein 2 isoform X1 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 139318472 SPSB4; (RefSeq) SPRY domain-containing SOCS box protein 4 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 139326070 SPSB1; (RefSeq) SPRY domain-containing SOCS box protein 1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 139325396 SPSB3; (RefSeq) SPRY domain-containing SOCS box protein 3 isoform X1 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 139310304 RAB40B; (RefSeq) ras-related protein Rab-40B K07928 RAB40; Ras-related protein Rab-40
E 139325217 RAB40C; (RefSeq) ras-related protein Rab-40C K07928 RAB40; Ras-related protein Rab-40
E 139314069 LRRC41; (RefSeq) leucine-rich repeat-containing protein 41 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 139323398 RSPRY1; (RefSeq) RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 139315662 ANKRD9; (RefSeq) ankyrin repeat domain-containing protein 9 K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 139321041 ankyrin repeat domain-containing protein 9-like K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 139308215 KLHDC1; (RefSeq) kelch domain-containing protein 1 isoform X1 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 139312479 SKP1; (RefSeq) S-phase kinase-associated protein 1 isoform X1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 139322111 FBXW8; (RefSeq) LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 139319223 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 139308637 cullin-9-like K11970 CUL9; cullin 9
E 139308645 cullin-9-like K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
E 139312667 ANAPC11; (RefSeq) anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 139314567 anaphase-promoting complex subunit 2-like K03349 APC2; anaphase-promoting complex subunit 2
E 139325815 ANAPC2; (RefSeq) anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 139314102 CDC20; (RefSeq) cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 139308285 FZR1; (RefSeq) fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 139319979 ANAPC1; (RefSeq) anaphase-promoting complex subunit 1 isoform X1 K03348 APC1; anaphase-promoting complex subunit 1
E 139320694 ANAPC4; (RefSeq) anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 139321527 ANAPC5; (RefSeq) anaphase-promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
E 139316200 CDC16; (RefSeq) cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 139321616 ANAPC7; (RefSeq) anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 139309634 CDC23; (RefSeq) cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 139320284 ANAPC10; (RefSeq) anaphase-promoting complex subunit 10 isoform X1 K03357 APC10; anaphase-promoting complex subunit 10
E 139325737 CDC26; (RefSeq) anaphase-promoting complex subunit CDC26 K03359 APC12; anaphase-promoting complex subunit 12
E 139318346 ANAPC13; (RefSeq) anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 139317169 ANAPC15; (RefSeq) anaphase-promoting complex subunit 15 isoform X1 K25228 APC15; anaphase-promoting complex subunit 15
E 139318124 ANAPC16; (RefSeq) anaphase-promoting complex subunit 16 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 139316216 BRCA2; (RefSeq) breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
D 139322776 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 139327078 BARD1; (RefSeq) BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 139308694 BABAM2; (RefSeq) BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
D 139307966 RAD51; (RefSeq) DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 139312377 RNF123; (RefSeq) E3 ubiquitin-protein ligase RNF123 isoform X1 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 139325634 UBAC1; (RefSeq) ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 139314519 SHARPIN; (RefSeq) sharpin isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 139314582 RBCK1; (RefSeq) LOW QUALITY PROTEIN: ranBP-type and C3HC4-type zinc finger-containing protein 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 139324758 RNF31; (RefSeq) E3 ubiquitin-protein ligase RNF31 isoform X1 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 139312388 RMND5B; (RefSeq) E3 ubiquitin-protein transferase RMND5B K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 139314789 RANBP9; (RefSeq) ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 139323780 RANBP10; (RefSeq) ran-binding protein 10 isoform X1 K23334 RANBP9_10; Ran-binding protein 9/10
D 139317978 ARMC8; (RefSeq) armadillo repeat-containing protein 8 isoform X1 K23336 ARMC8; armadillo repeat-containing protein 8
D 139316370 MAEA; (RefSeq) E3 ubiquitin-protein transferase MAEA K18624 MAEA; macrophage erythroblast attacher
D 139325211 GID4; (RefSeq) glucose-induced degradation protein 4 homolog isoform X1 K23335 GID4; glucose-induced degradation protein 4
D 139315468 GID8; (RefSeq) glucose-induced degradation protein 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 139308691 YPEL5; (RefSeq) protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 139308678 WDR26; (RefSeq) WD repeat-containing protein 26 isoform X1 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 139323535 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 139317365 TMUB1; (RefSeq) transmembrane and ubiquitin-like domain-containing protein 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 139308231 erlin-1-like K23341 ERLIN; erlin
D 139323087 ERLIN2; (RefSeq) erlin-2 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 139312730 LMBR1L; (RefSeq) protein LMBR1L isoform X1 K25215 LMBR1L; protein LMBR1L
D 139323535 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 139316268 UBAC2; (RefSeq) ubiquitin-associated domain-containing protein 2 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C STUB1-CHIC2 complex
D 139325361 STUB1; (RefSeq) E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
D 139320146 CHIC2; (RefSeq) cysteine-rich hydrophobic domain-containing protein 2 K28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 139319968 CAND1; (RefSeq) cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 139312253 cullin-associated NEDD8-dissociated protein 1-like K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 139309029 COMMD1; (RefSeq) COMM domain-containing protein 1 isoform X1 K22557 COMMD1; COMM domain containing 1
D 139318237 COMMD2; (RefSeq) COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 139317405 COMMD3; (RefSeq) COMM domain-containing protein 3 isoform X1 K22559 COMMD3; COMM domain containing 3
D 139323922 COMMD4; (RefSeq) COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 139322604 COMMD5; (RefSeq) COMM domain-containing protein 5 K22561 COMMD5; COMM domain containing 5
D 139316415 COMMD6; (RefSeq) COMM domain-containing protein 6 K22562 COMMD6; COMM domain containing 6
D 139314597 COMMD7; (RefSeq) COMM domain-containing protein 7 K22563 COMMD7; COMM domain containing 7
D 139326043 COMMD8; (RefSeq) COMM domain-containing protein 8 K22564 COMMD8; COMM domain containing 8
D 139307858 COMMD9; (RefSeq) COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 139313231 COMMD10; (RefSeq) COMM domain-containing protein 10 isoform X1 K22566 COMMD10; COMM domain containing 10
D 139310921 CCDC22; (RefSeq) coiled-coil domain-containing protein 22 isoform X1 K23343 CCDC22; coiled-coil domain-containing protein 22
D 139320340 DDRGK1; (RefSeq) DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 139313908 GLMN; (RefSeq) glomulin isoform X1 K23345 GLMN; glomulin
D 139314944 IVNS1ABP; (RefSeq) influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 139317926 UBXN7; (RefSeq) UBX domain-containing protein 7 K24350 UBXN7; UBX domain-containing protein 7
D 139322347 PACRG; (RefSeq) parkin coregulated gene protein K26163 PACRG; parkin coregulated gene protein
D 139313382 UBAP2; (RefSeq) ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 139322348 UBAP2L; (RefSeq) ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
D 139327576 UEVLD; (RefSeq) ubiquitin-conjugating enzyme E2 variant 3 K28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 139320180 UCHL1; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 139312345 BAP1; (RefSeq) ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 139316166 UCHL3; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 139313829 UCHL5; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 139314566 ubiquitin carboxyl-terminal hydrolase CYLD-like K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 139323771 CYLD; (RefSeq) ubiquitin carboxyl-terminal hydrolase CYLD isoform X1 K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 139313997 USP1; (RefSeq) ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 139323105 USP2; (RefSeq) ubiquitin carboxyl-terminal hydrolase 2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 139323863 USP3; (RefSeq) ubiquitin carboxyl-terminal hydrolase 3 isoform X1 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 139312372 USP4; (RefSeq) ubiquitin carboxyl-terminal hydrolase 4 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 139312879 USP11; (RefSeq) ubiquitin carboxyl-terminal hydrolase 11 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 139313071 USP5; (RefSeq) ubiquitin carboxyl-terminal hydrolase 5 isoform X1 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 139318759 USP13; (RefSeq) ubiquitin carboxyl-terminal hydrolase 13 isoform X1 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 139308473 USP32; (RefSeq) ubiquitin carboxyl-terminal hydrolase 32 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 139325489 USP7; (RefSeq) ubiquitin carboxyl-terminal hydrolase 7 isoform X1 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 139324163 USP8; (RefSeq) ubiquitin carboxyl-terminal hydrolase 8 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 139315212 USP24; (RefSeq) ubiquitin carboxyl-terminal hydrolase 24 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 139317225 USP9X; (RefSeq) ubiquitin carboxyl-terminal hydrolase 9X K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 139323458 USP10; (RefSeq) ubiquitin carboxyl-terminal hydrolase 10 isoform X1 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 139316997 USP12; (RefSeq) ubiquitin carboxyl-terminal hydrolase 12 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 139320425 USP46; (RefSeq) ubiquitin carboxyl-terminal hydrolase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 139322747 ubiquitin carboxyl-terminal hydrolase 12-like K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 139315867 USP14; (RefSeq) ubiquitin carboxyl-terminal hydrolase 14 isoform X1 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 139319955 USP15; (RefSeq) ubiquitin carboxyl-terminal hydrolase 15 isoform X1 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 139308889 USP45; (RefSeq) ubiquitin carboxyl-terminal hydrolase 45 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 139316118 USP16; (RefSeq) ubiquitin carboxyl-terminal hydrolase 16 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 139319231 USP18; (RefSeq) ubl carboxyl-terminal hydrolase 18 isoform X1 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 139312192 USP19; (RefSeq) ubiquitin carboxyl-terminal hydrolase 19 isoform X1 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 139313954 USP33; (RefSeq) ubiquitin carboxyl-terminal hydrolase 33 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 139325888 USP20; (RefSeq) ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 139322006 USP21; (RefSeq) ubiquitin carboxyl-terminal hydrolase 21 K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D 139325221 USP22; (RefSeq) ubiquitin carboxyl-terminal hydrolase 22 isoform X1 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 139316127 USP25; (RefSeq) ubiquitin carboxyl-terminal hydrolase 25 isoform X1 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 139324483 USP37; (RefSeq) ubiquitin carboxyl-terminal hydrolase 37 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 139323312 USP28; (RefSeq) ubiquitin carboxyl-terminal hydrolase 28 isoform X1 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 139321639 USP30; (RefSeq) ubiquitin carboxyl-terminal hydrolase 30 isoform X1 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 139325437 USP31; (RefSeq) ubiquitin carboxyl-terminal hydrolase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 139308597 USP34; (RefSeq) ubiquitin carboxyl-terminal hydrolase 34 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 139317117 USP35; (RefSeq) ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 139320063 USP38; (RefSeq) ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 139312681 USP36; (RefSeq) ubiquitin carboxyl-terminal hydrolase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 139325167 USP42; (RefSeq) ubiquitin carboxyl-terminal hydrolase 42 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 139310336 USP43; (RefSeq) ubiquitin carboxyl-terminal hydrolase 43 K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
D 139314189 USP49; (RefSeq) ubiquitin carboxyl-terminal hydrolase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 139319609 USP44; (RefSeq) ubiquitin carboxyl-terminal hydrolase 44 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 139309933 USP47; (RefSeq) ubiquitin carboxyl-terminal hydrolase 47 isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 139326169 USP48; (RefSeq) ubiquitin carboxyl-terminal hydrolase 48 isoform X1 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
D 139318082 USP54; (RefSeq) ubiquitin carboxyl-terminal hydrolase 54 K27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]
C OTU
D 139321607 OTUB1; (RefSeq) ubiquitin thioesterase OTUB1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 139325981 OTUD3; (RefSeq) OTU domain-containing protein 3 isoform X1 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 139310884 OTUD5; (RefSeq) OTU domain-containing protein 5 isoform X1 K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 139315712 OTUD6B; (RefSeq) deubiquitinase OTUD6B isoform X1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 139322446 OTUD7B; (RefSeq) OTU domain-containing protein 7B K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 139324013 OTUD7A; (RefSeq) OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 139316036 OTULIN; (RefSeq) ubiquitin thioesterase otulin K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
D 139323049 TNFAIP3; (RefSeq) tumor necrosis factor alpha-induced protein 3 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 139314711 VCPIP1; (RefSeq) deubiquitinating protein VCPIP1 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 139318241 ZRANB1; (RefSeq) ubiquitin thioesterase ZRANB1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 139315249 ATXN3; (RefSeq) ataxin-3 isoform X1 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 139319096 JOSD1; (RefSeq) josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 139322490 MINDY1; (RefSeq) ubiquitin carboxyl-terminal hydrolase MINDY-1 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 139323955 MINDY2; (RefSeq) ubiquitin carboxyl-terminal hydrolase MINDY-2 K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 139318652 MINDY4B; (RefSeq) inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 139322776 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 139315209 MYSM1; (RefSeq) deubiquitinase MYSM1 isoform X1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 139317527 MPND; (RefSeq) MPN domain-containing protein K24173 MPND; MPN domain-containing protein
D 139327219 PSMD14; (RefSeq) 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 139318511 STAMBPL1; (RefSeq) AMSH-like protease K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 139307909 deubiquitinase DESI2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 139308735 DESI2; (RefSeq) deubiquitinase DESI2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 139308855 ZUP1; (RefSeq) zinc finger-containing ubiquitin peptidase 1 K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 139318209 ABRAXAS2; (RefSeq) BRISC complex subunit Abraxas 2 isoform X1 K20799 FAM175B; BRISC complex subunit Abro1
D 139317685 BABAM1; (RefSeq) BRISC and BRCA1-A complex member 1 isoform X1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 139322776 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 139308694 BABAM2; (RefSeq) BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 139312838 SENP1; (RefSeq) sentrin-specific protease 1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 139318810 SENP2; (RefSeq) sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 139324900 SENP3; (RefSeq) sentrin-specific protease 3 K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C 139317850 SENP5; (RefSeq) sentrin-specific protease 5 isoform X1 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 139308923 SENP6; (RefSeq) sentrin-specific protease 6 isoform X1 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 139316180 SENP7; (RefSeq) sentrin-specific protease 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 139323917 SENP8; (RefSeq) sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 139316166 UCHL3; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 139319817 DESI1; (RefSeq) desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 139316222 USPL1; (RefSeq) SUMO-specific isopeptidase USPL1 isoform X1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 139312662 GPS1; (RefSeq) COP9 signalosome complex subunit 1 isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 139323833 COPS2; (RefSeq) COP9 signalosome complex subunit 2 isoform X1 K12176 COPS2; COP9 signalosome complex subunit 2
D 139325298 COPS3; (RefSeq) COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 139320051 COPS4; (RefSeq) COP9 signalosome complex subunit 4 isoform X1 K12178 COPS4; COP9 signalosome complex subunit 4
D 139315772 COPS5; (RefSeq) COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 139314609 COPS6; (RefSeq) COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 139311030 COPS7A; (RefSeq) COP9 signalosome complex subunit 7a K12180 COPS7; COP9 signalosome complex subunit 7
D 139309071 COPS8; (RefSeq) COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
D 139318260 COPS9; (RefSeq) COP9 signalosome complex subunit 9 K28062 COPS9; COP9 signalosome complex subunit 9
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 2, 2025