+E Ribosome biogenesis KO
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Ribosome Biogenesis - Plasmodium chabaudi
%
!
AEukaryotic type
B Sno RNPs
C Box C/D snoRNPs
D PCHAS_1035900 rRNA 2'-O-methyltransferase fibrillarin, putative K14563 NOP1; rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-]
D PCHAS_0914700 nucleolar protein 56, putative K14564 NOP56; nucleolar protein 56
D PCHAS_1207700 nucleolar protein 5, putative K14565 NOP58; nucleolar protein 58
D PCHAS_0920000 13 kDa ribonucleoprotein-associated protein, putative K12845 SNU13; U4/U6 small nuclear ribonucleoprotein SNU13
C Box H/ACA snoRNPs
D PCHAS_1026000 H/ACA ribonucleoprotein complex subunit 4, putative K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D PCHAS_1409900 H/ACA ribonucleoprotein complex subunit 1, putative K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
D PCHAS_1012700 H/ACA ribonucleoprotein complex subunit 3, putative K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
B 90S particles
C U3 small nucleolar RNA-associated proteins
D PCHAS_1328200 U3 small nucleolar ribonucleoprotein IMP3, putative K14560 IMP3; U3 small nucleolar ribonucleoprotein protein IMP3
D PCHAS_0721100 U3 small nucleolar ribonucleoprotein IMP4, putative K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D PCHAS_0511300 U3 small nucleolar ribonucleoprotein MPP10, putative K14559 MPP10; U3 small nucleolar RNA-associated protein MPP10
D PCHAS_1127900 RNA-binding protein, putative K14545 RRP7; ribosomal RNA-processing protein 7
D PCHAS_1228600 periodic tryptophan protein 2, putative K14558 PWP2; periodic tryptophan protein 2
D PCHAS_1133900 Sas10 domain-containing protein, putative K14767 UTP3; U3 small nucleolar RNA-associated protein 3
D PCHAS_0621800 U3 small nucleolar RNA-associated protein 7, putative K14768 UTP7; U3 small nucleolar RNA-associated protein 7
D PCHAS_1463100 U3 small nucleolar RNA-associated protein 11, putative K14769 UTP11; U3 small nucleolar RNA-associated protein 11
D PCHAS_1315100 U3 small nucleolar RNA-associated protein 12, putative K14556 DIP2; U3 small nucleolar RNA-associated protein 12
D PCHAS_1227700 U3 small nucleolar RNA-associated protein 14, putative K14567 UTP14; U3 small nucleolar RNA-associated protein 14
D PCHAS_1369500 U3 small nucleolar RNA-associated protein 15, putative K14549 UTP15; U3 small nucleolar RNA-associated protein 15
D PCHAS_1441300 WD repeat-containing protein, putative K14553 UTP18; U3 small nucleolar RNA-associated protein 18
D PCHAS_0608400 conserved Plasmodium protein, unknown function K14772 UTP20; U3 small nucleolar RNA-associated protein 20
D PCHAS_0721500 rRNA-processing protein FCF1, putative K14566 UTP24; U3 small nucleolar RNA-associated protein 24
C Helicases
D PCHAS_1025100 ATP-dependent RNA helicase DBP4, putative K14776 DDX10; ATP-dependent RNA helicase DDX10/DBP4 [EC:5.6.2.7]
D PCHAS_1129200 ATP-dependent RNA helicase HAS1, putative K13179 DDX18; ATP-dependent RNA helicase DDX18/HAS1 [EC:5.6.2.7]
D PCHAS_0317200 ATP-dependent RNA helicase DDX47, putative K14777 DDX47; ATP-dependent RNA helicase DDX47/RRP3 [EC:5.6.2.7]
D PCHAS_1352100 ATP-dependent RNA helicase DBP8, putative K14778 DDX49; ATP-dependent RNA helicase DDX49/DBP8 [EC:5.6.2.7]
D PCHAS_0818900 pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, putative K12820 DHX15; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
D PCHAS_1403100 ATP-dependent RNA helicase DHR1, putative K14780 DHX37; ATP-dependent RNA helicase DHX37/DHR1 [EC:5.6.2.6]
D PCHAS_0523300 eukaryotic initiation factor 4A-III, putative K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
C GTPase
D PCHAS_0205000 asparagine and aspartate rich protein 2, putative K14569 BMS1; ribosome biogenesis protein BMS1
C RNase
D PCHAS_1358600 RNA lariat debranching enzyme, putative K18328 DBR1; lariat debranching enzyme [EC:3.1.-.-]
C Kinase
D PCHAS_0905700 casein kinase 2, alpha subunit, putative K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
D PCHAS_0901100 casein kinase II beta chain, putative K03115 CSNK2B; casein kinase II subunit beta
D PCHAS_1360100 casein kinase II beta chain, putative K03115 CSNK2B; casein kinase II subunit beta
C Other 90S particles
D PCHAS_0603500 conserved Plasmodium protein, unknown function K14782 AATF; protein AATF/BFR2
D PCHAS_0718400 ribosomal RNA small subunit methyltransferase NEP1, putative K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D PCHAS_0619300 pre-rRNA-processing protein ESF2, putative K14785 ESF2; ESF2/ABP1 family protein
D PCHAS_0932900 protein KRI1, putative K14786 KRI1; protein KRI1
D PCHAS_0307500 KRR1 small subunit processome component, putative K06961 KRR1; ribosomal RNA assembly protein
D PCHAS_1434800 multiple RNA-binding domain-containing protein 1, putative K14787 MRD1; multiple RNA-binding domain-containing protein 1
D PCHAS_0505000 N-acetyltransferase, GNAT family, putative K14521 NAT10; N-acetyltransferase 10 [EC:2.3.1.-]
D PCHAS_1229400 nucleolar protein 10, putative K14788 NOL10; ribosome biogenesis protein ENP2
D PCHAS_1454500 periodic tryptophan protein 1, putative K14791 PWP1; periodic tryptophan protein 1
D PCHAS_1338800 RNA 3'-terminal phosphate cyclase-like protein, putative K11108 RCL1; RNA 3'-terminal phosphate cyclase-like protein
D PCHAS_1038400 rRNA biogenesis protein RRP5, putative K14792 RRP5; rRNA biogenesis protein RRP5
D PCHAS_0202300 rRNA biogenesis protein RRP36, putative K14795 RRP36; ribosomal RNA-processing protein 36
D PCHAS_1007700 protein SOF1, putative K11806 DCAF13; DDB1- and CUL4-associated factor 13
B Pre-40S particles
C Kinases
D PCHAS_1447800 serine/threonine protein kinase RIO1, putative K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D PCHAS_0521600 serine/threonine protein kinase RIO2, putative K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C Export and cytoplasmic maturation factors
D PCHAS_1027700 ribosomal RNA small subunit methyltransferase A1, putative K14191 DIM1; 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase [EC:2.1.1.183]
D PCHAS_1237500 18S rRNA (guanine-N(7))-methyltransferase, putative K19306 BUD23; 18S rRNA (guanine1575-N7)-methyltransferase [EC:2.1.1.309]
D PCHAS_0906500 essential nuclear protein 1, putative K14797 ENP1; essential nuclear protein 1
D PCHAS_0313300 conserved protein, unknown function K14798 LTV1; protein LTV1
D PCHAS_0729800 RNA-binding protein NOB1, putative K11883 NOB1; RNA-binding protein NOB1
D PCHAS_1337100 pre-rRNA-processing protein PNO1, putative K11884 PNO1; RNA-binding protein PNO1
D PCHAS_0914000 GTP-binding nuclear protein RAN/TC4, putative K07936 RAN; GTP-binding nuclear protein Ran
D PCHAS_0201200 adenylate kinase-like protein 1, putative K18532 AK6; adenylate kinase [EC:2.7.4.3]
D PCHAS_1318900 ribosome biogenesis protein TSR1, putative K14799 TSR1; pre-rRNA-processing protein TSR1
D PCHAS_0205300 pre-rRNA-processing protein TSR2, putative K14800 TSR2; pre-rRNA-processing protein TSR2
D PCHAS_1437700 ribosome biogenesis protein TSR3, putative K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D PCHAS_0615600 PDCD2 domain-containing protein, putative K14801 TSR4; pre-rRNA-processing protein TSR4
D PCHAS_1109700 PDCD2 domain-containing protein, putative K14801 TSR4; pre-rRNA-processing protein TSR4
D PCHAS_0402400 exportin-1, putative K14290 XPO1; exportin-1
D PCHAS_1424200 importin subunit beta, putative K14293 KPNB1; importin subunit beta-1
D PCHAS_1125900 transportin, putative K18752 TNPO1; transportin-1
D PCHAS_1239200 karyopherin beta, putative K20222 IPO5; importin-5
D PCHAS_0803900 importin-7, putative K20223 IPO7; importin-7
C Other pre-40S particles
D PCHAS_1143600 ABC transporter E family member 1, putative K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
B Pre-60S particles
C Helicases
D PCHAS_1312900 ATP-dependent RNA helicase DDX5, putative K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
D PCHAS_1443900 DNA helicase 60, putative K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
D PCHAS_1129200 ATP-dependent RNA helicase HAS1, putative K13179 DDX18; ATP-dependent RNA helicase DDX18/HAS1 [EC:5.6.2.7]
D PCHAS_1103700 ATP-dependent helicase, putative K16911 DDX21; ATP-dependent RNA helicase DDX21 [EC:5.6.2.7]
D PCHAS_1312200 ATP-dependent RNA helicase MAK5, putative K14805 DDX24; ATP-dependent RNA helicase DDX24/MAK5 [EC:5.6.2.7]
D PCHAS_1466700 ATP-dependent RNA helicase DRS1, putative K13181 DDX27; ATP-dependent RNA helicase DDX27 [EC:5.6.2.7]
D PCHAS_0620500 ATP-dependent RNA helicase DBP7, putative K14806 DDX31; ATP-dependent RNA helicase DDX31/DBP7 [EC:5.6.2.7]
D PCHAS_1003600 ATP-dependent RNA helicase DDX51, putative K14807 DDX51; ATP-dependent RNA helicase DDX51/DBP6 [EC:5.6.2.7]
D PCHAS_0934300 ATP-dependent RNA helicase DBP10, putative K14808 DDX54; ATP-dependent RNA helicase DDX54/DBP10 [EC:5.6.2.7]
D PCHAS_0101600 ATP-dependent RNA helicase, putative K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C GTPases
D PCHAS_1021200 nucleolar GTP-binding protein 2, putative K14537 NUG2; nuclear GTP-binding protein
D PCHAS_0111800 nucleolar GTP-binding protein 1, putative K06943 NOG1; nucleolar GTP-binding protein
D PCHAS_1014300 large subunit GTPase 1, putative K14539 LSG1; large subunit GTPase 1 [EC:3.6.1.-]
C RNases
D PCHAS_0810900 exoribonuclease, putative K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D RNase MRP
E PCHAS_1220800 ribonucleases P/MRP protein subunit POP1, putative K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
E PCHAS_1126100 ribonuclease P protein subunit p29, putative K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
E PCHAS_0908400 conserved Plasmodium protein, unknown function K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
C Kinases
C Export and cytoplasmic maturation factors
D PCHAS_1204500 DnaJ protein, putative K09506 DNAJA5; DnaJ homolog subfamily A member 5
D PCHAS_1352200 eukaryotic translation initiation factor 6, putative K03264 EIF6; translation initiation factor 6
D PCHAS_0721000 heat shock protein 70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PCHAS_1143000 ribosome biogenesis protein MRT4, putative K14815 MRT4; mRNA turnover protein 4
D PCHAS_0211800 60S ribosomal export protein NMD3, putative K07562 NMD3; 60S ribosomal export protein NMD3
D PCHAS_0914000 GTP-binding nuclear protein RAN/TC4, putative K07936 RAN; GTP-binding nuclear protein Ran
D PCHAS_1008300 zinc finger protein, putative K14816 REI1; pre-60S factor REI1
D PCHAS_1032400 ribosome maturation protein SBDS, putative K14574 SDO1; ribosome maturation protein SDO1
D PCHAS_0402400 exportin-1, putative K14290 XPO1; exportin-1
D PCHAS_1424200 importin subunit beta, putative K14293 KPNB1; importin subunit beta-1
D PCHAS_1125900 transportin, putative K18752 TNPO1; transportin-1
D PCHAS_1239200 karyopherin beta, putative K20222 IPO5; importin-5
D PCHAS_0803900 importin-7, putative K20223 IPO7; importin-7
D PCHAS_0408100 dual specificity protein phosphatase, putative K14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
D PCHAS_1322100 protein tyrosine phosphatase, putative K14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
C 5-FMC complex
C Ribosome quality control proteins
D PCHAS_1106100 transcription factor 25, putative K24970 TCF25; transcription factor 25
D PCHAS_0603400 conserved protein, unknown function K24971 NEMF; nuclear export mediator factor NEMF
D PCHAS_1118100 cell division cycle protein 48 homologue, putative K13525 VCP; transitional endoplasmic reticulum ATPase
D PCHAS_1107000 nuclear protein localization protein 4, putative K14015 NPLOC4; nuclear protein localization protein 4
D PCHAS_0817800 ubiquitin fusion degradation protein 1, putative K14016 UFD1; ubiquitin fusion degradation protein 1
D PCHAS_1025500 ubiquitin fusion degradation protein 1, putative K14016 UFD1; ubiquitin fusion degradation protein 1
D PCHAS_1240000 ubiquitin fusion degradation protein 1, putative K14016 UFD1; ubiquitin fusion degradation protein 1
D PCHAS_0109500 peptidyl-tRNA hydrolase PTRHD1, putative K05969 PTRHD1; peptidyl-tRNA hydrolase PTRHD1 [EC:3.1.1.29]
C Other pre-60S particles
D PCHAS_0211900 ribosome biogenesis protein BRX1, putative K14820 BRX1; ribosome biogenesis protein BRX1
D PCHAS_1332400 zinc finger protein, putative K14821 BUD20; bud site selection protein 20
D PCHAS_0512500 rRNA-processing protein EBP2, putative K14823 EBP2; rRNA-processing protein EBP2
D PCHAS_1037200 ribosome biogenesis protein BOP1, putative K14824 ERB1; ribosome biogenesis protein ERB1
D PCHAS_0303700 protein MAK16, putative K14831 MAK16; protein MAK16
D PCHAS_1011200 dynein-related AAA-type ATPase, putative K14572 MDN1; midasin
D PCHAS_1334700 60S ribosome subunit biogenesis protein NIP7, putative K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7
D PCHAS_1358300 nucleolar complex protein 2, putative K14833 NOC2; nucleolar complex protein 2
D PCHAS_0927300 rRNA (cytosine-C(5))-methyltransferase, putative K14835 NOP2; 25S rRNA (cytosine2870-C5)-methyltransferase [EC:2.1.1.310]
D PCHAS_1037100 RNA-binding protein, putative K14573 NOP4; nucleolar protein 4
D PCHAS_0504300 RNA-binding protein 34, putative K14837 NOP12; nucleolar protein 12
D PCHAS_0805400 ribosomal protein S8e, putative K14842 NSA2; ribosome biogenesis protein NSA2
D PCHAS_0905100 pescadillo homolog, putative K14843 PES1; pescadillo
D PCHAS_1119800 mRNA-binding protein PUF3, putative K14844 PUF6; pumilio homology domain family member 6
D PCHAS_1454500 periodic tryptophan protein 1, putative K14791 PWP1; periodic tryptophan protein 1
D PCHAS_1425000 AAA family ATPase, putative K14571 RIX7; ribosome biogenesis ATPase
D PCHAS_0823000 ribosome production factor 1, putative K14846 RPF1; ribosome production factor 1
D PCHAS_0512600 nucleolar preribosomal assembly protein, putative K14847 RPF2; ribosome production factor 2
D PCHAS_0723900 ribosome assembly protein RRB1, putative K14848 RRB1; ribosome assembly protein RRB1
D PCHAS_0832200 nucleolar protein Nop52, putative K14849 RRP1; ribosomal RNA-processing protein 1
D PCHAS_0826300 ribosomal RNA-processing protein 8, putative K14850 RRP8; ribosomal RNA-processing protein 8 [EC:2.1.1.287]
D PCHAS_0920900 ribosome biogenesis regulatory protein, putative K14852 RRS1; regulator of ribosome biosynthesis
D PCHAS_0704300 ribosome assembly protein 4, putative K14855 RSA4; ribosome assembly protein 4
D PCHAS_0615500 protein SDA1, putative K14856 SDA1; protein SDA1
D PCHAS_1130400 large subunit rRNA methyltransferase, putative K14857 SPB1; AdoMet-dependent rRNA methyltransferase SPB1 [EC:2.1.1.-]
D PCHAS_1128800 ribosome biogenesis protein YTM1, putative K14863 WDR12; ribosome biogenesis protein
D PCHAS_0818200 zinc finger protein, putative K23309 ZNHIT3; zinc finger HIT domain-containing protein 3
B Other ribosome biogenesis factors
C PCHAS_1343700 protein BCP1, putative K15262 BCP1; protein BCP1
C PCHAS_0907700 conserved Plasmodium protein, unknown function K21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]
C PCHAS_0504700 rRNA (cytosine-C(5))-methyltransferase, putative K15264 NSUN5; 25S rRNA (cytosine2278-C5)-methyltransferase [EC:2.1.1.311]
C PCHAS_0317100 rRNA methyltransferase, putative K15507 MRM1; 21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-]
C PCHAS_0904100 DNA replication ATP-dependent helicase/nuclease DNA2, putative K19036 IGHMBP2; ATP-dependent RNA/DNA helicase IGHMBP2 [EC:5.6.2.5 5.6.2.3]
C PCHAS_1009900 GTPase Era, putative K03595 era; GTPase
C PCHAS_1017100 proliferation-associated protein 2g4, putative K26736 PA2G4; ERBB-3 binding protein
C PCHAS_0511400 mitochondrial ribosomal protein S22 precursor, putative K27906 METTL17; ribosome assembly protein METTL17/RSM22, mitochondrial
C PCHAS_1009200 GTP-binding protein, putative K19828 MTG1; mitochondrial GTPase 1
C PCHAS_0107000 GTP-binding protein, putative K03979 obgE; GTPase [EC:3.6.5.-]
C PCHAS_1031700 GTP-binding protein Obg1, putative K03979 obgE; GTPase [EC:3.6.5.-]
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AProkaryotic type
B Sno RNPs
C Box C/D snoRNPs
D PCHAS_0914700 nucleolar protein 56, putative K14564 NOP56; nucleolar protein 56
D PCHAS_1020200 60S ribosomal protein L7-3, putative K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
C Box H/ACA snoRNPs
D PCHAS_1026000 H/ACA ribonucleoprotein complex subunit 4, putative K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D PCHAS_1012700 H/ACA ribonucleoprotein complex subunit 3, putative K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
B rRNA transcription factors
B rRNA modification factors
C 16S rRNA modification factors
D PCHAS_1453600 S-adenosyl-methyltransferase, putative K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
C 23S rRNA modification factors
D PCHAS_1410000 ribosomal RNA methyltransferase, putative K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
B ribosomal protein modification factors
B rRNA processing factors
B rRNA helicases
B GTPases
C PCHAS_1009900 GTPase Era, putative K03595 era; GTPase
C PCHAS_0107000 GTP-binding protein, putative K03979 obgE; GTPase [EC:3.6.5.-]
C PCHAS_1031700 GTP-binding protein Obg1, putative K03979 obgE; GTPase [EC:3.6.5.-]
B Other maturation factors
C PCHAS_0604300 threonylcarbamoyl-AMP synthase, putative K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
#
ARelated small nucleolar RNAs
B Box C/D snoRNAs
C SnoRNAs involved in processing reactions
D PCHAS_0408450 small nucleolar RNA Me18S-Um1356 K14881 SNORD32_33; small nucleolar RNA SNORD32/33
D PCHAS_0906450 small nucleolar RNA snR61/Z1/Z11 K14887 SNORD38; small nucleolar RNA SNORD38
D PCHAS_1020340 small nucleolar RNA snoR23 K14880 SNORD59; small nucleolar RNA SNORD59
C SnoRNAs act as guides for 2'-O-ribose methylation
D PCHAS_1020320 small nucleolar RNA snoR25 K14882 SNORD25; small nucleolar RNA SNORD25
D PCHAS_0906550 small nucleolar RNA snoR12 K14900 SNORD27; small nucleolar RNA SNORD27
D PCHAS_1020180 small nucleolar RNA snoR28 K26304 SNORD49; small nucleolar RNA SNORD49
D PCHAS_0317540 small nucleolar RNA snoR01 K26311 SNORD61; small nucleolar RNA SNORD61
D PCHAS_0906540 small nucleolar RNA SNORD127 K27142 SNORD127; small nucleolar RNA SNORD127
D PCHAS_1351310 small nucleolar RNA snoR18 K14891 SNR65; small nucleolar RNA SNR65
B Box H/ACA snoRNAs
C SnoRNAs involved in processing reactions
C SnoRNAs act as guides for pseudouridynation
B Other snoRNA
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 22, 2025