+D Protein KO
#
Membrane Trafficking - Plasmodium chabaudi
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
C Kinases and associated proteins
D PCHAS_0201500 phosphatidylinositol-4-phosphate 5-kinase, putative K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PCHAS_0105000 nucleoside diphosphate kinase, putative K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D PCHAS_1141900 nucleoside diphosphate kinase b, putative K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PCHAS_0725300 calmodulin-like protein, putative K02183 CALM; calmodulin
D PCHAS_1011500 calmodulin, putative K02183 CALM; calmodulin
D PCHAS_1025200 calmodulin, putative K02183 CALM; calmodulin
D PCHAS_0112600 syntaxin-binding protein, putative K15292 STXBP1; syntaxin-binding protein 1
D PCHAS_1420600 SNARE protein, putative K08509 SNAP29; synaptosomal-associated protein 29
D PCHAS_1123300 GAS8-like protein, putative K19942 GAS8; dynein regulatory complex subunit 4
D PCHAS_1458100 GAS8-like protein, putative K19942 GAS8; dynein regulatory complex subunit 4
D PCHAS_0910900 GTPase-activating protein, putative K19953 GRTP1; TBC1 domain family member 6
D PCHAS_1309600 geranylgeranyl transferase type-2 subunit alpha, putative K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PCHAS_0102000 geranylgeranyl transferase type-2 subunit beta, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PCHAS_1432000 geranylgeranyl transferase type-2 subunit beta, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
C Exocyst complex assembly proteins
D PCHAS_0621000 conserved Plasmodium protein, unknown function K10881 SHFM1; 26 proteasome complex subunit DSS1
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D PCHAS_0309800 syntaxin, putative K08486 STX1B_2_3; syntaxin 1B/2/3
D PCHAS_1013700 SNARE protein, putative K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D PCHAS_1458700 SNARE protein, putative K08489 STX16; syntaxin 16
C Stx-cisGolgi
D PCHAS_1351400 Qa-SNARE protein, putative K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
C NPSN
D PCHAS_1315600 SNARE protein, putative K08494 NSPN; novel plant SNARE
C Gos1 (Gos28)
C Bos1 / Membrin
C Sec20
B SNAP-25[C] (Qc)
C STX6
C STX8
C STX10
C Bet1
D PCHAS_1210300 BET1-like protein, putative K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
D PCHAS_1420600 SNARE protein, putative K08509 SNAP29; synaptosomal-associated protein 29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D PCHAS_0934000 SNARE protein, putative K08515 VAMP7; vesicle-associated membrane protein 7
D PCHAS_1403600 SNARE protein, putative K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D PCHAS_0812000 SNARE protein, putative K08516 YKT6; synaptobrevin homolog YKT6
D PCHAS_1344500 SNARE protein, putative K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D PCHAS_1219100 protein transport protein SEC22, putative K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D PCHAS_0112600 syntaxin-binding protein, putative K15292 STXBP1; syntaxin-binding protein 1
D PCHAS_0517900 Sec1 family protein, putative K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D PCHAS_0108900 palmitoyltransferase DHHC2, putative K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCHAS_0512100 palmitoyltransferase DHHC10, putative K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCHAS_0912200 palmitoyltransferase DHHC9, putative K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCHAS_1243400 palmitoyltransferase DHHC7, putative K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCHAS_0314700 palmitoyltransferase DHHC11, putative K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D PCHAS_1342400 palmitoyltransferase DHHC5, putative K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D PCHAS_0402500 N-ethylmaleimide-sensitive fusion protein, putative K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PCHAS_1108300 alpha-soluble NSF attachment protein, putative K15296 NAPA; alpha-soluble NSF attachment protein
D PCHAS_1118100 cell division cycle protein 48 homologue, putative K13525 VCP; transitional endoplasmic reticulum ATPase
D PCHAS_1223000 ubiquitin regulatory protein, putative K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D PCHAS_1436700 clathrin heavy chain, putative K04646 CLTC; clathrin heavy chain
C Dynamin
D PCHAS_0520600 dynamin-like protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D PCHAS_0316100 AP-2 complex subunit sigma, putative K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D PCHAS_0509300 EF-hand calcium-binding domain-containing protein, putative K12472 EPS15; epidermal growth factor receptor substrate 15
D PCHAS_0721000 heat shock protein 70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D PCHAS_0201500 phosphatidylinositol-4-phosphate 5-kinase, putative K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
C Kinases
D PCHAS_1462800 serine/threonine protein kinase, putative K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D PCHAS_0520600 dynamin-like protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D PCHAS_0505200 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D PCHAS_0520600 dynamin-like protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D PCHAS_1360300 myosin A, putative K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
C Kinases
D PCHAS_1114500 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C Phospholipase C
C Sorting nexins
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PCHAS_1114500 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PCHAS_0315200 vacuolar protein sorting-associated protein 45, putative K12479 VPS45; vacuolar protein sorting-associated protein 45
D PCHAS_0917000 palmitoyltransferase DHHC3, putative K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
D PCHAS_0505200 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D PCHAS_1241400 ADP-ribosylation factor GTPase-activating protein, putative K12486 SMAP; stromal membrane-associated protein
D PCHAS_1335800 rab GTPase activator, putative K21841 TBC1D24; TBC1 domain family member 24
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D PCHAS_0731000 phosphatidylinositol 4-kinase, putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D PCHAS_0419100 ras-related protein RAB7, putative K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D PCHAS_0907200 vacuolar protein sorting-associated protein 35, putative K18468 VPS35; vacuolar protein sorting-associated protein 35
D PCHAS_1036300 vacuolar protein sorting-associated protein 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
D PCHAS_1465500 vacuolar protein sorting-associated protein 26, putative K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C FERRY complex
C Rab associated proteins
D PCHAS_1114500 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PCHAS_1130000 proteasome subunit alpha type-7, putative K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PCHAS_1340900 GTPase-activating protein, putative K18469 TBC1D5; TBC1 domain family member 5
D PCHAS_0929400 oxysterol-binding protein, putative K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D PCHAS_1309600 geranylgeranyl transferase type-2 subunit alpha, putative K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PCHAS_0102000 geranylgeranyl transferase type-2 subunit beta, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PCHAS_1432000 geranylgeranyl transferase type-2 subunit beta, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D PCHAS_1225800 N-acetyltransferase, GNAT family, putative K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
C ESCRT-II complex
C ESCRT-III complex
D PCHAS_0416100 vacuolar protein sorting-associated protein 46, putative K12197 CHMP1; charged multivesicular body protein 1
D PCHAS_0723700 vacuolar protein sorting-associated protein 2, putative K12191 CHMP2A; charged multivesicular body protein 2A
D PCHAS_1459100 vacuolar-sorting protein SNF7, putative K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D PCHAS_1308900 vacuolar protein sorting-associated protein 60, putative K12198 CHMP5; charged multivesicular body protein 5
D PCHAS_1324500 vacuolar protein sorting-associated protein 4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D PCHAS_0208500 vacuolar protein sorting-associated protein VTA1, putative K12199 VTA1; vacuolar protein sorting-associated protein VTA1
B Tethering complex
C CORVET complex
D PCHAS_1101500 vacuolar protein sorting-associated protein 11, putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D PCHAS_1456600 vacuolar protein sorting-associated protein 16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D PCHAS_1410100 vacuolar protein sorting-associated protein 18, putative K20181 VPS18; vacuolar protein sorting-associated protein 18
D PCHAS_0836300 vacuolar protein sorting-associated protein 33, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D PCHAS_1101500 vacuolar protein sorting-associated protein 11, putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D PCHAS_1456600 vacuolar protein sorting-associated protein 16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D PCHAS_1410100 vacuolar protein sorting-associated protein 18, putative K20181 VPS18; vacuolar protein sorting-associated protein 18
D PCHAS_0836300 vacuolar protein sorting-associated protein 33, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D PCHAS_1142400 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D PCHAS_1465700 AP-3 complex subunit sigma, putative K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Lysosomal membrane proteins
D PCHAS_1356300 LMBR1 domain-containing protein, putative K14617 LMBRD1; LMBR1 domain-containing protein 1
C Others
D PCHAS_1370000 vacuolar fusion protein MON1, putative K20195 MON1; vacuolar fusion protein MON1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
C Rab4 associated proteins
D PCHAS_0415800 dynein intermediate light chain, putative K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D PCHAS_1447600 protein transport protein SEC13, putative K14004 SEC13; protein transport protein SEC13
C Other Rab GTPase associated proteins
D PCHAS_0403700 EH domain-containing protein, putative K12483 EHD1; EH domain-containing protein 1
D PCHAS_0904800 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D PCHAS_0208400 vacuolar protein sorting-associated protein 51, putative K20296 ANG2; vacuolar protein sorting-associated protein 51
D PCHAS_1343600 vacuolar protein sorting-associated protein 52, putative K20298 VPS52; vacuolar protein sorting-associated protein 52
D PCHAS_0209500 vacuolar protein sorting-associated protein 53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D PCHAS_1243500 F-actin-capping protein subunit alpha, putative K10364 CAPZA; F-actin-capping protein subunit alpha
D PCHAS_1233000 F-actin-capping protein subunit beta, putative K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D PCHAS_1036300 vacuolar protein sorting-associated protein 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D PCHAS_1438800 protein TSSC1, putative K23289 EIPR1; EARP and GARP complex-interacting protein 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PCHAS_0504400 flagellar outer arm dynein-associated protein, putative K10419 DYNLRB; dynein light chain roadblock-type
D PCHAS_1363900 VPS13 domain-containing protein, putative K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D PCHAS_0505200 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D PCHAS_0518600 ADP-ribosylation factor, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
D PCHAS_1135500 ADP-ribosylation factor, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
C Arf GTPase associated proteins
D PCHAS_1460100 ADP-ribosylation factor GTPase-activating protein, putative K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D PCHAS_1226300 GTPase-activating protein, putative K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D PCHAS_1241400 ADP-ribosylation factor GTPase-activating protein, putative K12486 SMAP; stromal membrane-associated protein
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D PCHAS_1231200 conserved oligomeric Golgi complex subunit 4, putative K20291 COG4; conserved oligomeric Golgi complex subunit 4
C GARP complex
D PCHAS_0208400 vacuolar protein sorting-associated protein 51, putative K20296 ANG2; vacuolar protein sorting-associated protein 51
D PCHAS_1343600 vacuolar protein sorting-associated protein 52, putative K20298 VPS52; vacuolar protein sorting-associated protein 52
D PCHAS_0209500 vacuolar protein sorting-associated protein 53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
C TRAPP complex II
D PCHAS_1037800 trafficking protein particle complex subunit 1, putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PCHAS_0723200 trafficking protein particle complex subunit 2-like protein, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCHAS_1351700 trafficking protein particle complex subunit 2, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCHAS_0729600 trafficking protein particle complex subunit 3, putative K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PCHAS_0409600 trafficking protein particle complex subunit 4, putative K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PCHAS_0612700 trafficking protein particle complex subunit 5, putative K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PCHAS_1117400 trafficking protein particle complex subunit 6A, putative K20304 TRAPPC6; trafficking protein particle complex subunit 6
D PCHAS_1104400 trafficking protein particle complex subunit 8, putative K20305 TRAPPC8; trafficking protein particle complex subunit 8
D PCHAS_1453200 conserved protein, unknown function K20309 TRAPPC12; trafficking protein particle complex subunit 12
D PCHAS_1101400 conserved protein, unknown function K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D PCHAS_1322500 AP-1 complex subunit gamma, putative K12391 AP1G1; AP-1 complex subunit gamma-1
D PCHAS_1243100 AP-1 complex subunit beta, putative K12392 AP1B1; AP-1 complex subunit beta-1
D PCHAS_1411800 AP-1 complex subunit mu-1, putative K12393 AP1M; AP-1 complex subunit mu
D PCHAS_0914300 AP-1 complex subunit sigma, putative K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D PCHAS_1465700 AP-3 complex subunit sigma, putative K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D PCHAS_0418200 AP-4 complex subunit epsilon, putative K12400 AP4E1; AP-4 complex subunit epsilon-1
D PCHAS_0915700 AP-4 complex subunit mu, putative K12402 AP4M1; AP-4 complex subunit mu-1
D PCHAS_0523700 AP-4 complex subunit sigma, putative K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D PCHAS_0731000 phosphatidylinositol 4-kinase, putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PCHAS_0201500 phosphatidylinositol-4-phosphate 5-kinase, putative K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PCHAS_1012600 HID1 domain-containing protein, putative K27894 HID1; protein HID1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D PCHAS_0727900 small GTP-binding protein sar1, putative K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D PCHAS_1447600 protein transport protein SEC13, putative K14004 SEC13; protein transport protein SEC13
D PCHAS_0313100 protein transport protein SEC31, putative K14005 SEC31; protein transport protein SEC31
D PCHAS_0717300 protein transport protein SEC23, putative K14006 SEC23; protein transport protein SEC23
D PCHAS_1136700 protein transport protein Sec24A, putative K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D PCHAS_1037800 trafficking protein particle complex subunit 1, putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PCHAS_0723200 trafficking protein particle complex subunit 2-like protein, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCHAS_1351700 trafficking protein particle complex subunit 2, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCHAS_0729600 trafficking protein particle complex subunit 3, putative K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PCHAS_0409600 trafficking protein particle complex subunit 4, putative K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PCHAS_0612700 trafficking protein particle complex subunit 5, putative K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PCHAS_1117400 trafficking protein particle complex subunit 6A, putative K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D PCHAS_1242100 transmembrane emp24 domain-containing protein, putative K20346 TMED4_9_11; p24 family protein alpha
D PCHAS_0522700 transmembrane emp24 domain-containing protein, putative K20347 TMED2; p24 family protein beta-1
D PCHAS_1414800 transmembrane emp24 domain-containing protein, putative K20347 TMED2; p24 family protein beta-1
D PCHAS_1352600 transmembrane emp24 domain-containing protein, putative K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D PCHAS_0935200 protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D PCHAS_0931700 protein disulfide isomerase related protein, putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
C Rab associated proteins
D PCHAS_1365900 TBC domain protein, putative K20360 TBC1D22; TBC1 domain family member 2
D PCHAS_1320300 Yos1-like protein, putative K22939 IER3IP1; immediate early response 3-interacting protein 1
C ER-Golgi intermediate compartment (ERGIC) proteins
D PCHAS_0819200 endoplasmic reticulum chaperone BiP, putative K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D PCHAS_0106000 coatomer alpha subunit, putative K05236 COPA; coatomer subunit alpha
D PCHAS_1015700 coatomer subunit beta, putative K17301 COPB1; coatomer subunit beta
D PCHAS_0416400 coatomer subunit beta, putative K17302 COPB2; coatomer subunit beta'
D PCHAS_0705100 coatomer subunit gamma, putative K17267 COPG; coatomer subunit gamma
D PCHAS_0932300 coatomer subunit delta, putative K20471 COPD; coatomer subunit delta
D PCHAS_1222900 coatomer subunit epsilon, putative K17268 COPE; coatomer subunit epsilon
D PCHAS_0726500 coatomer subunit zeta, putative K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
C Golgi to ER traffic proteins (GET)
D PCHAS_0726100 arsenical pump-driving ATPase, putative K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D PCHAS_1305700 conserved protein, unknown function K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
C Rab associated proteins
D PCHAS_1129700 ER lumen protein retaining receptor, putative K10949 KDELR; ER lumen protein retaining receptor
D PCHAS_1365900 TBC domain protein, putative K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D PCHAS_0929400 oxysterol-binding protein, putative K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
C FXYD proteins
C YIPF proteins
D PCHAS_1339900 Yip1 protein, putative K20363 YIPF5_7; protein YIPF5/7
D PCHAS_0703400 protein YIPF6, putative K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D PCHAS_1033300 ER membrane protein complex subunit 2, putative K23563 EMC2; ER membrane protein complex subunit 2
D PCHAS_1135900 ER membrane protein complex subunit 3, putative K23564 EMC3; ER membrane protein complex subunit 3
D PCHAS_1010300 ER membrane protein complex subunit 4, putative K23565 EMC4; ER membrane protein complex subunit 4
D PCHAS_1432100 ER membrane protein complex subunit 6, putative K23567 EMC6; ER membrane protein complex subunit 6
D PCHAS_0710400 ER membrane protein complex subunit 8, putative K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D PCHAS_1363600 protein transport protein SEC61 subunit alpha, putative K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PCHAS_0718100 protein transport protein SEC61 subunit beta, putative K09481 SEC61B; protein transport protein SEC61 subunit beta
D PCHAS_0309100 Sec61-gamma subunit of protein translocation complex, putative K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D PCHAS_1137800 transmembrane and coiled-coil domain-containing protein 1, putative K21891 TMCO1; calcium load-activated calcium channel
D PCHAS_0806700 conserved protein, unknown function K24962 CCDC47; PAT complex subunit CCDC47
D PCHAS_1205900 transmembrane protein 147, putative K26498 TMEM147; BOS complex subunit TMEM147
D PCHAS_1212400 conserved Plasmodium protein, unknown function K26499 NCLN; BOS complex subunit NCLN
C Post-GPI attachment to proteins factors (PGAP)
C Others
D PCHAS_0517900 Sec1 family protein, putative K19998 SCFD1; sec1 family domain-containing protein 1
D PCHAS_1004200 TMEM33 domain-containing protein, putative K20724 TMEM33; transmembrane protein 33
D PCHAS_1210400 protein ARV1, putative K21848 ARV1; lipid intermediate transporter
D PCHAS_1123400 sphingomyelin synthase 1, putative K22697 SAMD8; ceramide phosphoethanolamine synthase / phosphatidylethanolamine phospholipase C [EC:2.7.8.48 3.1.4.62]
D PCHAS_1027400 protein SEY1, putative K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
C Atg1 complex
C PI3K complex
D PCHAS_1114500 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C ATG9 transmembrane protein
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D PCHAS_1337800 autophagy-related protein 12, putative K08336 ATG12; ubiquitin-like protein ATG12
C Atg8 conjugation proteins
D PCHAS_0504200 autophagy-related protein 8, putative K08341 GABARAP; GABA(A) receptor-associated protein
D PCHAS_0416600 autophagy-related protein 3, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D PCHAS_0833400 M18 aspartyl aminopeptidase, putative K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
D PCHAS_1117700 conserved protein, unknown function K19513 CLEC16A; protein CLEC16A
C Other mitophagy associated proteins
D PCHAS_1122400 hexokinase, putative K00844 HK; hexokinase [EC:2.7.1.1]
B Pexophagy
C Selective cargos
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D PCHAS_1118100 cell division cycle protein 48 homologue, putative K13525 VCP; transitional endoplasmic reticulum ATPase
D PCHAS_0805200 E3 ubiquitin-protein ligase, putative K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B ER-phagy
C ER-phagy recepters
D PCHAS_1305400 translocation protein SEC62, putative K12275 SEC62; translocation protein SEC62
C Other ER-phagy associated proteins
C ER stress-related proteins
D PCHAS_0819200 endoplasmic reticulum chaperone BiP, putative K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D PCHAS_1439300 endoplasmin, putative K09487 HSP90B; heat shock protein 90kDa beta
D PCHAS_0210500 eukaryotic translation initiation factor 2 subunit alpha, putative K03237 EIF2S1; translation initiation factor 2 subunit 1
B Chaperone mediated autophagy (CMA)
C Selective cargos
D PCHAS_1311800 fructose-bisphosphate aldolase, putative K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D PCHAS_1329700 glyceraldehyde-3-phosphate dehydrogenase, putative K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PCHAS_0916200 phosphoglycerate mutase, putative K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PCHAS_0520200 pyruvate kinase 2, putative K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PCHAS_1125100 pyruvate kinase, putative K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PCHAS_0910100 ubiquitin domain-containing protein DSK2, putative K04523 UBQLN; ubiquilin
D PCHAS_0929600 ubiquitin-like protein, putative K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D PCHAS_0721000 heat shock protein 70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PCHAS_0806000 heat shock protein 90, putative K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D PCHAS_1242700 Hsc70-interacting protein, putative K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D PCHAS_1132800 elongation factor 1-alpha, putative K03231 EEF1A; elongation factor 1-alpha
D PCHAS_1132900 elongation factor 1-alpha, putative K03231 EEF1A; elongation factor 1-alpha
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
C mTORC2 complex
C SEACIT/GATOR1 complex
C SEACAT/GATOR2 complex
D PCHAS_1447600 protein transport protein SEC13, putative K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
C Rab associated proteins
C Others
D PCHAS_0826500 protein phosphatase-beta, putative K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PCHAS_0623400 type 2A phosphatase-associated protein 42, putative K17606 IGBP1; immunoglobulin-binding protein 1
D PCHAS_1212000 autophagy-related protein 18, putative K22991 WDR45; WD repeat-containing protein 45
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D PCHAS_1360300 myosin A, putative K10356 MYO1; myosin I
C Arp2/3 complex
D PCHAS_0915000 actin-related protein 2/3 complex subunit 1, putative K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
C Nucleation-promoting factors (NPFs)
C Others
D PCHAS_1102800 actin-depolymerizing factor 1, putative K05765 CFL; cofilin
D PCHAS_1137000 actin-depolymerizing factor 2, putative K05765 CFL; cofilin
B Mucins
C Membrane bound mucins
C Secretory mucins
B MARVEL domain-containing proteins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
D PCHAS_1223900 ras-related protein Rab-18, putative K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D PCHAS_1206100 rho GTPase-activating protein, putative K18470 ARHGAP1; Rho GTPase-activating protein 1
C Rho guanine nucleotide exchange factors (GEFs)
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 6, 2025