+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Pochonia chlamydosporia
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E VFPPC_01423 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E VFPPC_01400 cell division control protein 2 K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]
E VFPPC_14661 serine/threonine-protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E VFPPC_02896 mRNA capping enzyme alpha subunit K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
D Cap binding complex
E VFPPC_05765 cap binding protein K12882 NCBP1; nuclear cap-binding protein subunit 1
E VFPPC_04314 RNA recognition motif domain-containing protein K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E VFPPC_13363 cleavage and polyadenylation specific factor 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
D Pre-mRNA cleavage factor IIm (CFIIm)
E VFPPC_07604 CLP1 protein K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E VFPPC_03421 mRNA cleavage factor complex component Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E VFPPC_11161 protein CFT1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E VFPPC_07753 cleavage and polyadenylylation specificity factor K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E VFPPC_15922 endoribonuclease ysh1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E VFPPC_08292 Zinc finger CCCH type domain-containing protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E VFPPC_07131 Fip1 like protein K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E VFPPC_03071 DWNN domain-containing protein K15541 MPE1; protein MPE1
E VFPPC_02587 polyadenylation factor subunit 2 K15542 PFS2; polyadenylation factor subunit 2
E VFPPC_04477 histone H3 methyltransferase complex and RNA cleavage factor II complex, subunit SWD2 K14962 WDR82; COMPASS component SWD2
E VFPPC_08431 serine/threonine-protein phosphatase PP-Z K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E VFPPC_13319 serine/threonine-protein phosphatase PP1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E VFPPC_08352 RNA polymerase II subunit A K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E VFPPC_00272 RNA recognition motif containing protein K14407 CSTF2; cleavage stimulation factor subunit 2
E VFPPC_17857 CFIA complex component Rna14 K14408 CSTF3; cleavage stimulation factor subunit 3
E VFPPC_00297 mRNA cleavage and polyadenylation specificity factor complex subunit K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E VFPPC_00633 LSM domain-containing protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E VFPPC_06231 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E VFPPC_16655 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E VFPPC_09594 small nuclear ribonucleoprotein SmF K11098 SNRPF; small nuclear ribonucleoprotein F
E VFPPC_14508 LSM domain-containing protein K11099 SNRPG; small nuclear ribonucleoprotein G
E VFPPC_07753 cleavage and polyadenylylation specificity factor K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E VFPPC_15922 endoribonuclease ysh1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E VFPPC_00272 RNA recognition motif containing protein K14407 CSTF2; cleavage stimulation factor subunit 2
E VFPPC_00297 mRNA cleavage and polyadenylation specificity factor complex subunit K06100 SYMPK; symplekin
D DRB sensitivity inducing factor (DSIF) complex
E VFPPC_14669 transcriptional elongation protein Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
E VFPPC_09768 transcription initiation protein spt5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E VFPPC_07169 hypothetical protein K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
D Poly(A) addition factors
E VFPPC_13650 poly(A) polymerase K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
C Other processing factors
D VFPPC_09829 zinc finger protein RTS2 K13102 KIN; DNA/RNA-binding protein KIN17
D VFPPC_00650 arsenite resistance protein Ars2 K27103 SRRT; serrate RNA effector molecule
D VFPPC_05562 nuclear polyadenylated rna-binding protein K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E VFPPC_08758 RNA recognition motif domain-containing protein K12876 RBM8A; RNA-binding protein 8A
E VFPPC_12968 RNA recognition motif domain-containing protein K12881 THOC4; THO complex subunit 4
E VFPPC_02980 RNA binding protein K12881 THOC4; THO complex subunit 4
E VFPPC_04789 ATP-dependent RNA helicase SUB2 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E VFPPC_14011 eukaryotic initiation factor 4A K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E VFPPC_13128 hypothetical protein K25178 CCDC174; coiled-coil domain-containing protein 174
E VFPPC_07033 Sin3-associated polypeptide Sap18 K14324 SAP18; histone deacetylase complex subunit SAP18
E VFPPC_08618 nucleotide-binding, alpha-beta plait K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E VFPPC_00643 PWI domain mRNA processing protein K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E VFPPC_04463 nuclear matrix protein K12878 THOC1; THO complex subunit 1
E VFPPC_07624 tho2 protein K12879 THOC2; THO complex subunit 2
E VFPPC_16182 hypothetical protein K12880 THOC3; THO complex subunit 3
E VFPPC_12968 RNA recognition motif domain-containing protein K12881 THOC4; THO complex subunit 4
E VFPPC_02980 RNA binding protein K12881 THOC4; THO complex subunit 4
E VFPPC_12835 THO complex, subunit 5 K13174 THOC5; THO complex subunit 5
D TREX-2 complex
E VFPPC_05243 PCI domain-containing protein K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E VFPPC_16894 DSS1/SEM1 family domain-containing protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E VFPPC_01389 centrin K16466 CETN3; centrin-3
E VFPPC_05685 MCM3-associated protein K23719 SAC3; nuclear mRNA export protein SAC3
D Nuclear pore complex
E VFPPC_01790 TPR/MLP1/MLP2-like protein K09291 TPR; nucleoprotein TPR
E VFPPC_09527 poly(A)+ RNA export protein K14298 RAE1; mRNA export factor
E VFPPC_01680 protein transporter sec-13 K14004 SEC13; protein transport protein SEC13
E VFPPC_16136 nuclear pore protein NUP57 K14308 NUP54; nuclear pore complex protein Nup54
E VFPPC_03005 nucleoporin, NSP1-lik K14306 NUP62; nuclear pore complex protein Nup62
E VFPPC_01994 nuclear pore protein (Nic96) K14309 NUP93; nuclear pore complex protein Nup93
E VFPPC_01388 nucleoporin SONB K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E VFPPC_05516 nuclear pore complex protein K14301 NUP107; nuclear pore complex protein Nup107
E VFPPC_07335 nuclear pore complex subunit K14300 NUP133; nuclear pore complex protein Nup133
E VFPPC_04376 nucleoporin K14311 NUP188; nuclear pore complex protein Nup188
E VFPPC_07646 non-repetitive nucleoporin K14312 NUP155; nuclear pore complex protein Nup155
E VFPPC_04351 hypothetical protein K14310 NUP205; nuclear pore complex protein Nup205
E VFPPC_14163 nucleoporin NUP49/NSP49 K14307 NUPL1; nucleoporin p58/p45
E VFPPC_12978 nuclear envelope protein K14315 NDC1; nucleoporin NDC1
E VFPPC_05120 nuclear pore complex subunit K14299 SEH1; nucleoporin SEH1
E VFPPC_00271 hypothetical protein K18715 NUP159; nucleoporin NUP159
E VFPPC_07981 CCCH zinc finger domain-containing protein K18716 NUP42; nucleoporin NUP42
E VFPPC_04313 nuclear pore complex protein An-Nup82 K18719 NUP82; nucleoporin NUP82
E VFPPC_01389 centrin K16466 CETN3; centrin-3
E VFPPC_05876 RNA export mediator Gle1 K18723 GLE1; nucleoporin GLE1
E VFPPC_00437 mRNA export factor mex67 K14284 NXF; nuclear RNA export factor
E VFPPC_06122 nuclear transport factor 2, Eukaryote K14285 NXT1_2; NTF2-related export protein 1/2
E VFPPC_05695 nuclear pore complex component K18724 POM34; nucleoporin POM34
E VFPPC_08139 nuclear envelope pore membrane protein K18725 POM152; nucleoporin POM152
D Ran-mediated transport factors
E VFPPC_12843 GTP-binding nuclear protein RAN/TC4 K07936 RAN; GTP-binding nuclear protein Ran
E VFPPC_16750 UBX domain-containing protein K18726 FAF2; FAS-associated factor 2
E VFPPC_04361 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
E VFPPC_00996 exportin-1 K14290 XPO1; exportin-1
E VFPPC_00452 ran GTPase activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E VFPPC_08906 translation Initiation Factor Eif4e K03259 EIF4E; translation initiation factor 4E
E VFPPC_13924 eukaryotic translation initiation factor 4E-4 K03259 EIF4E; translation initiation factor 4E
E VFPPC_05633 hypothetical protein K03257 EIF4A; translation initiation factor 4A
E VFPPC_03009 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E VFPPC_04466 eukaryotic translation initiation factor subunit eIF-4F K03260 EIF4G; translation initiation factor 4G
E VFPPC_06973 RNA recognition motif containing protein K03258 EIF4B; translation initiation factor 4B
E VFPPC_05872 ATP-dependent RNA helicase ded1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E VFPPC_04725 DEAD/DEAH box RNA helicase K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E VFPPC_07151 GYF domain-containing protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E VFPPC_01444 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E VFPPC_06615 antiviral helicase SKI2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E VFPPC_09036 activating signal cointegrator 1 complex subunit 3 K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]
E VFPPC_05411 PUA domain-containing protein K07575 MCTS; malignant T-cell-amplified sequence
E VFPPC_15195 density-regulated protein DRP1 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E VFPPC_09146 RNA binding protein Pym K14294 WIBG; partner of Y14 and mago
E VFPPC_00134 heterogeneous nuclear ribonucleoprotein HRP1 K14411 MSI; RNA-binding protein Musashi
E VFPPC_01549 elongation factor Tu GTP binding domain-containing protein K14416 HBS1; elongation factor 1 alpha-like protein
E VFPPC_01218 pelota K06965 PELO; protein pelota
E VFPPC_00138 rrm-type rna binding protein K14396 PABPN1; polyadenylate-binding protein 2
E VFPPC_09590 ATP-dependent RNA helicase DBP5 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E VFPPC_07090 pre-mRNA splicing factor syf-1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E VFPPC_04164 DNA-binding SAP K18732 SARNP; SAP domain-containing ribonucleoprotein
E VFPPC_10549 regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E VFPPC_02377 regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E VFPPC_04680 Ran exchange factor Prp20/Pim1 K11493 RCC1; regulator of chromosome condensation
E VFPPC_05022 GANP domain-containing protein K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E VFPPC_02917 eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E VFPPC_01376 eukaryotic peptide chain release factor GTP-binding subunit K03267 ERF3; peptide chain release factor subunit 3
E VFPPC_03160 ATP-dependent helicase NAM7 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E VFPPC_03536 nonsense-mediated mRNA decay factor K14327 UPF2; regulator of nonsense transcripts 2
E VFPPC_02030 nonsense-mediated mRNA decay protein K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E VFPPC_14528 serine/threonine-protein phosphatase PP2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E VFPPC_04455 protein phosphatase PP2A regulatory subunit A K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E VFPPC_05475 protein phosphatase PP2A regulatory subunit B K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E VFPPC_06168 serine/threonine-protein phosphatase 2A regulatory subunit delta 1 isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E VFPPC_11776 serine/threonine protein phosphatase 2A K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E VFPPC_07151 GYF domain-containing protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E VFPPC_01183 GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E VFPPC_00670 CPL (NUC119) domain-containing protein K14844 PUF6; pumilio homology domain family member 6
E VFPPC_00611 KH domain RNA binding protein K18738 HEK; heterogeneous nuclear rnp K-like protein
E VFPPC_02860 KH domain RNA-binding protein K18738 HEK; heterogeneous nuclear rnp K-like protein
E VFPPC_09779 class V myosin K10357 MYO5; myosin V
D Factors that have mRNA localization signals
D Trans-acting binding proteins
E VFPPC_03455 far upstream element-binding protein 2 K13210 FUBP; far upstream element-binding protein
E VFPPC_04839 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
E VFPPC_10347 hypothetical protein K03233 EEF1G; elongation factor 1-gamma
E VFPPC_14671 elongation factor 1 gamma domain-containing protein K03233 EEF1G; elongation factor 1-gamma
E VFPPC_16795 hypothetical protein K03233 EEF1G; elongation factor 1-gamma
D Other mRNA localization factors
E VFPPC_05877 cell wall biogenesis protein phosphatase Ssd1 K18748 SSD1; protein SSD1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E VFPPC_05920 exonuclease Kem1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E VFPPC_08026 eukaryotic translation initiation factor 2c K11593 ELF2C; eukaryotic translation initiation factor 2C
E VFPPC_08906 translation Initiation Factor Eif4e K03259 EIF4E; translation initiation factor 4E
E VFPPC_13924 eukaryotic translation initiation factor 4E-4 K03259 EIF4E; translation initiation factor 4E
E VFPPC_03160 ATP-dependent helicase NAM7 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E VFPPC_05872 ATP-dependent RNA helicase ded1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E VFPPC_04725 DEAD/DEAH box RNA helicase K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E VFPPC_07760 ATP-dependent RNA helicase DHH1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E VFPPC_15282 like-Sm ribonucleoprotein (LSM)-related domain-containing protein K18749 LSM14; protein LSM14
E VFPPC_04131 importin beta-2 subunit K18752 TNPO1; transportin-1
E VFPPC_02718 cAMP-dependent protein kinase type 2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E VFPPC_04662 protein kinase DC2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E VFPPC_05542 La domain family K18757 LARP1; la-related protein 1
D P-body specific factors
E VFPPC_04480 decapping enzyme Dcp2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E VFPPC_12982 Sm ribonucleoprotein (LSM)-related domain-containing protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E VFPPC_15089 small nuclear ribonucleoprotein LSM2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E VFPPC_13019 Sm ribonucleoprotein (LSM)-related domain-containing protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E VFPPC_15672 LSM domain-containing protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E VFPPC_13908 LSM domain-containing protein K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E VFPPC_12760 U6 snRNA-associated protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E VFPPC_14103 U6 snRNA-associated protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E VFPPC_09779 class V myosin K10357 MYO5; myosin V
E VFPPC_00295 tubulin alpha-1 chain K07374 TUBA; tubulin alpha
E VFPPC_15442 tubulin alpha-1 chain K07374 TUBA; tubulin alpha
E VFPPC_01398 CCR4-NOT core subunit CDC39 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E VFPPC_09144 NOT2 family protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E VFPPC_09443 CCR4-NOT transcription complex K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E VFPPC_07893 transcription factor K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E VFPPC_17748 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E VFPPC_15349 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E VFPPC_06734 PABP-dependent poly(A) nuclease 3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E VFPPC_04989 topisomerase II associated protein K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E VFPPC_04356 FDF domain-containing protein K12615 EDC3; enhancer of mRNA-decapping protein 3
E VFPPC_03536 nonsense-mediated mRNA decay factor K14327 UPF2; regulator of nonsense transcripts 2
E VFPPC_02030 nonsense-mediated mRNA decay protein K14328 UPF3; regulator of nonsense transcripts 3
E VFPPC_09175 RNA polymerase Rpb7-like domain-containing protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
D Stress granule specific factors
E VFPPC_04473 nuclear and cytoplasmic polyadenylated RNA-binding protein pub1 K13201 TIA1; nucleolysin TIA-1/TIAR
E VFPPC_01444 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E VFPPC_02660 ntf2 and rrm domain-containing protein K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E VFPPC_08125 eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E VFPPC_10435 eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E VFPPC_05633 hypothetical protein K03257 EIF4A; translation initiation factor 4A
E VFPPC_03009 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E VFPPC_14011 eukaryotic initiation factor 4A K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E VFPPC_06973 RNA recognition motif containing protein K03258 EIF4B; translation initiation factor 4B
E VFPPC_04466 eukaryotic translation initiation factor subunit eIF-4F K03260 EIF4G; translation initiation factor 4G
E VFPPC_00437 mRNA export factor mex67 K14284 NXF; nuclear RNA export factor
E VFPPC_03476 histone deacetylase clr3 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E VFPPC_04480 decapping enzyme Dcp2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E VFPPC_07760 ATP-dependent RNA helicase DHH1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E VFPPC_04356 FDF domain-containing protein K12615 EDC3; enhancer of mRNA-decapping protein 3
E VFPPC_04989 topisomerase II associated protein K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E VFPPC_12982 Sm ribonucleoprotein (LSM)-related domain-containing protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E VFPPC_15089 small nuclear ribonucleoprotein LSM2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E VFPPC_13019 Sm ribonucleoprotein (LSM)-related domain-containing protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E VFPPC_15672 LSM domain-containing protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E VFPPC_13908 LSM domain-containing protein K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E VFPPC_12760 U6 snRNA-associated protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E VFPPC_14103 U6 snRNA-associated protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
D 5' exonucleases
E VFPPC_05920 exonuclease Kem1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E VFPPC_01111 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E VFPPC_09052 scavenger mRNA decapping enzyme K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E VFPPC_05733 exosomal core protein CSL4 K07573 CSL4; exosome complex component CSL4
E VFPPC_07339 exoribonuclease K03679 RRP4; exosome complex component RRP4
E VFPPC_04809 exosome complex exonuclease RRP40 K03681 RRP40; exosome complex component RRP40
E VFPPC_10964 exosome complex exonuclease RRP41 K11600 RRP41; exosome complex component RRP41
E VFPPC_12842 ribosomal protein S5 domain 2-type fold domain-containing protein K12590 RRP46; exosome complex component RRP46
E VFPPC_07096 3' exoribonuclease K12587 MTR3; exosome complex component MTR3
E VFPPC_12985 3' exoribonuclease family protein (Rrp42) K12589 RRP42; exosome complex component RRP42
E VFPPC_08594 3' exoribonuclease family protein K12586 RRP43; exosome complex component RRP43
E VFPPC_04343 3' exoribonuclease K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E VFPPC_00718 mitotic control protein dis3 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E VFPPC_07966 3'-5' exonuclease domain-containing protein K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E VFPPC_13718 exosome-associated family protein K12592 C1D; exosome complex protein LRP1
E VFPPC_18251 DEAD/DEAH box helicase K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E VFPPC_01341 poly(A) RNA polymerase cid14 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E VFPPC_02325 ATP-dependent RNA helicase DOB1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E VFPPC_06615 antiviral helicase SKI2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E VFPPC_08077 antiviral protein (Ski3) K12600 SKI3; superkiller protein 3
E VFPPC_00978 meiotic recombination protein Ski8/Rec14 K12601 SKI8; superkiller protein 8
D Ccr4-NOT complex
E VFPPC_07893 transcription factor K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E VFPPC_01398 CCR4-NOT core subunit CDC39 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E VFPPC_09144 NOT2 family protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E VFPPC_09443 CCR4-NOT transcription complex K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E VFPPC_17748 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E VFPPC_13131 cell differentiation protein rcd1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E VFPPC_13882 ABC transporter K12608 CAF16; CCR4-NOT complex subunit CAF16
E VFPPC_00335 PH domain-containing protein K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120
D Pan complex
E VFPPC_15349 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E VFPPC_06734 PABP-dependent poly(A) nuclease 3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E VFPPC_09052 scavenger mRNA decapping enzyme K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E VFPPC_02570 hypothetical protein K26109 NRDE2; nuclear exosome regulator NRDE2
C Other degradation factors
D RNases
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AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E VFPPC_00842 abhydrolase domain-containing protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
E VFPPC_00288 RNA exonuclease Rex2 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E VFPPC_05493 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E VFPPC_14899 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E VFPPC_08600 6-phosphofructokinase alpha subunit K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E VFPPC_09114 heat shock protein SSC1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
E VFPPC_00747 heat shock protein 60, mitochondrial precursor K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E VFPPC_07339 exoribonuclease K03679 RRP4; exosome complex component RRP4
E VFPPC_05733 exosomal core protein CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E VFPPC_10964 exosome complex exonuclease RRP41 K11600 RRP41; exosome complex component RRP41
E VFPPC_12985 3' exoribonuclease family protein (Rrp42) K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024