+E Ubiquitin system KO
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Ubiquitin System - Pelecanus crispus (Dalmatian pelican)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 104030846 RPS27A; ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 104026291 SUMO2; small ubiquitin-related modifier 2 K12160 SUMO; small ubiquitin-related modifier
C 104031951 SUMO1; small ubiquitin-related modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 104026780 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
C 104032083 gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 104028490 URM1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
C 104027312 UFM1; ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 104035151 ZFAND4; AN1-type zinc finger protein 4 isoform X1 K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
B UBL-activating enzymes
C 104034706 SAE1; SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 104031283 UBA2; LOW QUALITY PROTEIN: SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 104030452 UBA3; NEDD8-activating enzyme E1 catalytic subunit K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 104024380 NAE1; LOW QUALITY PROTEIN: NEDD8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 104031173 MOCS3; LOW QUALITY PROTEIN: adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 104036657 UBA5; ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 104024570 UBA6; ubiquitin-like modifier-activating enzyme 6 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 104038219 ATG7; ubiquitin-like modifier-activating enzyme ATG7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 104032011 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 104026093 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 104028112 ubiquitin-conjugating enzyme E2 D3 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 104037339 UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 104034604 ubiquitin-conjugating enzyme E2 D2-like K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 104032197 UBE2E1; ubiquitin-conjugating enzyme E2 E1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 104038578 UBE2E3; ubiquitin-conjugating enzyme E2 E3 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 104026186 UBE2G1; ubiquitin-conjugating enzyme E2 G1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 104039014 UBE2G2; ubiquitin-conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 104033322 UBE2H; ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 104033192 UBE2J1; ubiquitin-conjugating enzyme E2 J1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 104024555 UBE2J2; ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 104034853 UBE2K; ubiquitin-conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 104036039 UBE2L3; ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 104035917 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 104035092 UBE2O; LOW QUALITY PROTEIN: E2/E3 hybrid ubiquitin-protein ligase UBE2O K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 104025659 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 104038072 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 104027133 CDC34; ubiquitin-conjugating enzyme E2 R1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 104032729 UBE2R2; ubiquitin-conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 104034995 UBE2T; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 104025739 UBE2W; ubiquitin-conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 104025310 UBE2Z; ubiquitin-conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
B UBL-conjugating enzymes
C 104037439 UBE2I; SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 104025269 UBE2F; NEDD8-conjugating enzyme UBE2F K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 104033922 ATG3; ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C 104034112 UBE3A; ubiquitin-protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 104029218 UBE3B; ubiquitin-protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 104038744 UBE3C; ubiquitin-protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 104038286 UBE3D; E3 ubiquitin-protein ligase E3D K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 104028855 SMURF1; E3 ubiquitin-protein ligase SMURF1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 104030523 SMURF2; E3 ubiquitin-protein ligase SMURF2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 104031435 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 104024808 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 104034240 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 104037014 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 104030679 UBR5; E3 ubiquitin-protein ligase UBR5 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 104037194 G2E3; G2/M phase-specific E3 ubiquitin-protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 104033228 probable E3 ubiquitin-protein ligase HERC1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 104038296 probable E3 ubiquitin-protein ligase HERC3 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 104034042 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X1 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 104038951 HACE1; E3 ubiquitin-protein ligase HACE1 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 104032141 HECW2; E3 ubiquitin-protein ligase HECW2 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 104037033 HECTD1; E3 ubiquitin-protein ligase HECTD1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 104028475 E3 ubiquitin-protein ligase HECTD3-like K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 104037675 HECTD3; E3 ubiquitin-protein ligase HECTD3 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 104025883 HECTD4; probable E3 ubiquitin-protein ligase HECTD4 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 104025981 NDFIP1; NEDD4 family-interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
D 104032616 N4BP3; NEDD4-binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
D 104035182 UPF0472 protein C16orf72 homolog K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
B U-box type E3
C 104029488 UBE4A; ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 104028048 UBE4B; ubiquitin conjugation factor E4 B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 104025079 STUB1; E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 104038457 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 104027760 PRPF19; pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 104026565 RBBP6; E3 ubiquitin-protein ligase RBBP6 K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 104034714 UBOX5; RING finger protein 37 isoform X1 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 104027905 RNF20; E3 ubiquitin-protein ligase BRE1A K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 104037646 CBL; E3 ubiquitin-protein ligase CBL K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 104033521 CBLB; E3 ubiquitin-protein ligase CBL-B K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 104028540 SIAH1; E3 ubiquitin-protein ligase SIAH1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 104030919 E3 ubiquitin-protein ligase SIAH2-like K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 104038852 LNX1; E3 ubiquitin-protein ligase LNX K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 104027310 LNX2; ligand of Numb protein X 2 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 104024506 ligand of Numb protein X 2-like K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 104027913 PDZRN4; LOW QUALITY PROTEIN: PDZ domain-containing RING finger protein 4 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
D 104028117 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase PDZRN3-like K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 104025655 E3 ubiquitin-protein ligase MARCH1-like K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 104036274 MARCH8; E3 ubiquitin-protein ligase MARCH8 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 104030898 MARCH2; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MARCH2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 104036670 MARCH3; E3 ubiquitin-protein ligase MARCH3 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 104033457 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MARCH11-like K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 104025820 MARCH5; E3 ubiquitin-protein ligase MARCH5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 104032551 MARCH6; E3 ubiquitin-protein ligase MARCH6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 104025647 MARCH7; E3 ubiquitin-protein ligase MARCH7 isoform X1 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 104032001 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 104030917 MDM4; LOW QUALITY PROTEIN: protein Mdm4 K10127 MDM4; protein Mdm4
C NFX1 proteins
D 104024372 NFXL1; NF-X1-type zinc finger protein NFXL1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 104025905 PELI2; E3 ubiquitin-protein ligase pellino homolog 2 K11964 PELI; pellino [EC:2.3.2.27]
D 104034471 PELI1; E3 ubiquitin-protein ligase pellino homolog 1 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 104025806 PEX10; peroxisome biogenesis factor 10 K13346 PEX10; peroxin-10
D 104029242 PEX12; peroxisome assembly protein 12 K13345 PEX12; peroxin-12
D 104027661 PEX2; peroxisome biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 104032882 ankyrin repeat and IBR domain-containing protein 1-like K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 104028916 E3 ubiquitin-protein ligase arih1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 104032692 ARIH2; E3 ubiquitin-protein ligase ARIH2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 104037420 RNF14; E3 ubiquitin-protein ligase RNF14 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 104038764 RNF19A; E3 ubiquitin-protein ligase RNF19A K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 104028442 RNF19B; E3 ubiquitin-protein ligase RNF19B K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 104031599 RFFL; E3 ubiquitin-protein ligase rififylin K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 104035837 RNF34; E3 ubiquitin-protein ligase RNF34 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 104028059 RNF144B; E3 ubiquitin-protein ligase RNF144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 104025369 RNF144A; probable E3 ubiquitin-protein ligase RNF144A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 104034745 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 104033826 RNF169; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 104031918 RNF216; E3 ubiquitin-protein ligase RNF216 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 104023893 RNF217; probable E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 104031731 LOW QUALITY PROTEIN: TNF receptor-associated factor 2-like K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 104024317 TRAF5; TNF receptor-associated factor 5 K09849 TRAF5; TNF receptor-associated factor 5
D 104023738 TRAF6; TNF receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 104029949 TRAF7; E3 ubiquitin-protein ligase TRAF7 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 104031661 TRIM2; tripartite motif-containing protein 2 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 104038787 TRIM7; tripartite motif-containing protein 7 K12000 TRIM7; tripartite motif-containing protein 7
D 104036063 tripartite motif-containing protein 7-like K12000 TRIM7; tripartite motif-containing protein 7
D 104036207 zinc finger protein RFP-like K12000 TRIM7; tripartite motif-containing protein 7
D 104031519 TRIM67; tripartite motif-containing protein 67 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 104034996 TRIM13; E3 ubiquitin-protein ligase TRIM13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 104037291 TRIM14; tripartite motif-containing protein 14 K12004 TRIM14; tripartite motif-containing protein 14
D 104032898 E3 ubiquitin-protein ligase Midline-1 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 104029826 E3 ubiquitin-protein ligase TRIM23-like K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 104036216 TRIM24; LOW QUALITY PROTEIN: transcription intermediary factor 1-alpha K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 104033672 TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 104036623 TRIM29; tripartite motif-containing protein 29 K12010 TRIM29; tripartite motif-containing protein 29
D 104028469 TRIM32; E3 ubiquitin-protein ligase TRIM32 K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
D 104030435 TRIM33; E3 ubiquitin-protein ligase TRIM33 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 104038736 LOW QUALITY PROTEIN: tripartite motif-containing protein 35-like K12012 TRIM35; tripartite motif-containing protein 35
D 104028208 TRIM36; E3 ubiquitin-protein ligase TRIM36 isoform X1 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 104029561 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X1 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 104034625 E3 ubiquitin-protein ligase TRIM39-like K12015 TRIM39; tripartite motif-containing protein 39 [EC:2.3.2.27]
D 104036208 E3 ubiquitin-protein ligase TRIM39-like K12015 TRIM39; tripartite motif-containing protein 39 [EC:2.3.2.27]
D 104028944 TRIM42; LOW QUALITY PROTEIN: tripartite motif-containing protein 42 K12018 TRIM42; tripartite motif-containing protein 42
D 104032044 TRIM45; tripartite motif-containing protein 45 K12021 TRIM45; tripartite motif-containing protein 45
D 104035052 TRIM47; tripartite motif-containing protein 47 K12023 TRIM47; tripartite motif-containing protein 47
D 104031946 TRIM50; E3 ubiquitin-protein ligase TRIM50 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 104024743 TRIM55; tripartite motif-containing protein 55 K10654 TRIM55; tripartite motif-containing protein 55
D 104036277 TRIM59; tripartite motif-containing protein 59 K12028 TRIM59; tripartite motif-containing protein 59
D 104031397 TRIM65; LOW QUALITY PROTEIN: tripartite motif-containing protein 65 K12031 TRIM65; tripartite motif-containing protein 65
D 104036251 tripartite motif-containing protein 66-like K12032 TRIM66; tripartite motif-containing protein 66
D 104034571 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 104024292 E3 ubiquitin-protein ligase UBR2 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 104031383 UBR3; E3 ubiquitin-protein ligase UBR3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 104027705 UBR4; E3 ubiquitin-protein ligase UBR4 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 104033106 UBR7; putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 104024460 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 104025239 BFAR; bifunctional apoptosis regulator K15684 BFAR; bifunctional apoptosis regulator
D 104024478 BIRC2; baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 104026276 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase XIAP-like K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 104037179 BIRC7; baculoviral IAP repeat-containing protein 7 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 104035971 BRAP; BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 104037885 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 104024757 CBLL1; E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 104038525 CHFR; E3 ubiquitin-protein ligase CHFR isoform X1 K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 104024818 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 104035676 DTX1; E3 ubiquitin-protein ligase DTX1 K06058 DTX; deltex [EC:2.3.2.27]
D 104025513 DTX3L; E3 ubiquitin-protein ligase DTX3L K06058 DTX; deltex [EC:2.3.2.27]
D 104038517 FANCL; E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 104030453 KCMF1; E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 104036632 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 104038101 LTN1; E3 ubiquitin-protein ligase listerin K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 104027050 MAP3K1; mitogen-activated protein kinase kinase kinase 1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 104038992 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 104032342 MGRN1; E3 ubiquitin-protein ligase MGRN1 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 104034813 MIB2; E3 ubiquitin-protein ligase MIB2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 104033458 E3 ubiquitin-protein ligase MIB1-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 104029714 MIB1; E3 ubiquitin-protein ligase MIB1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 104024077 probable E3 ubiquitin-protein ligase makorin-2 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 104038779 MKRN1; E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 104024360 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 104037073 mitochondrial ubiquitin ligase activator of nfkb 1-A-like K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 104035084 MYLIP; E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 104024397 NEURL1B; E3 ubiquitin-protein ligase NEURL1B K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 104030816 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 104030729 RNF219; LOW QUALITY PROTEIN: RING finger protein 219 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 104034532 PJA2; E3 ubiquitin-protein ligase Praja-2 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 104032674 RAD18; E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 104023743 RAG1; V(D)J recombination-activating protein 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 104036999 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 104024254 RC3H2; roquin-2 isoform X1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 104037531 RC3H1; roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 104025564 RFWD3; E3 ubiquitin-protein ligase RFWD3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 104025179 RNF2; E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 104036822 RNF4; E3 ubiquitin-protein ligase RNF4 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 104025809 RNF185; E3 ubiquitin-protein ligase RNF185 isoform X1 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 104024236 RNF6; E3 ubiquitin-protein ligase RNF6 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 104026717 RNF8; E3 ubiquitin-protein ligase RNF8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 104035074 RNF10; RING finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 104030292 RNF11; RING finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 104030974 RLIM; E3 ubiquitin-protein ligase RLIM K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 104025646 RNF13; E3 ubiquitin-protein ligase RNF13 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 104037556 RNF25; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 104027824 RNF26; RING finger protein 26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 104025482 RNF38; E3 ubiquitin-protein ligase RNF38 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 104034233 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase NRDP1-like K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 104027099 RNF43; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF43 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 104030285 RNF103; E3 ubiquitin-protein ligase RNF103 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 104035677 RNF126; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF126 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 104027411 LOW QUALITY PROTEIN: RING finger protein 175-like K15698 RNF121_175; RING finger protein 121/175
D 104032165 RNF123; E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 104034445 RNF125; E3 ubiquitin-protein ligase RNF125 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 104036328 RNF128; E3 ubiquitin-protein ligase RNF128 K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 104028649 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X1 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 104030434 RNF138; E3 ubiquitin-protein ligase RNF138 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 104025776 RNF139; E3 ubiquitin-protein ligase RNF139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 104037505 LOW QUALITY PROTEIN: RING finger protein 145-like K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 104029362 RNF146; E3 ubiquitin-protein ligase RNF146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 104027895 RNF149; E3 ubiquitin-protein ligase RNF149 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 104032259 RNF152; E3 ubiquitin-protein ligase RNF152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 104025319 RNF165; RING finger protein 165 K17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
D 104029229 RNF166; RING finger protein 166 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 104025864 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X1 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 104031788 RNF180; E3 ubiquitin-protein ligase RNF180 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 104027893 RNF182; E3 ubiquitin-protein ligase RNF182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 104034550 RNF186; RING finger protein 186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 104034916 RNF213; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF213 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 104037327 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X1 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 104025403 RNFT1; RING finger and transmembrane domain-containing protein 1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 104037863 SHPRH; E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 104033844 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase SH3RF1-like K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 104029861 HLTF; helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 104025969 TMEM129; E3 ubiquitin-protein ligase TM129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 104026144 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 104028874 TRAIP; E3 ubiquitin-protein ligase TRAIP K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 104031472 TTC3; E3 ubiquitin-protein ligase TTC3 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 104038733 UHRF1; E3 ubiquitin-protein ligase UHRF1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 104038347 UHRF2; E3 ubiquitin-protein ligase UHRF2 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 104024361 ZNF598; zinc finger protein 598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 104024903 ZFP91; E3 ubiquitin-protein ligase ZFP91 K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 104029346 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 104031910 E3 ubiquitin-protein ligase RNF13-like K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
B Atypical E3
C 104035384 E4F1; transcription factor E4F1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 104025546 NSMCE1; non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C 104026144 TOPORS; E3 ubiquitin-protein ligase Topors K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 104036813 RANBP2; E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 104031717 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 104039051 PIAS2; E3 SUMO-protein ligase PIAS2 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 104032082 PIAS3; E3 SUMO-protein ligase PIAS3 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 104024280 PIAS4; E3 SUMO-protein ligase PIAS4 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 104037522 RNF212; probable E3 SUMO-protein ligase RNF212 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 104031651 ZBED1; zinc finger BED domain-containing protein 1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 104032442 ZNF451; zinc finger protein 451 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 104036135 HERC3; probable E3 ubiquitin-protein ligase HERC3 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 104031429 UFL1; E3 UFM1-protein ligase 1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 104027501 DCUN1D1; DCN1-like protein 1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 104025691 DCN1-like protein 2 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 104035708 DCUN1D3; DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 104026964 DCUN1D4; DCN1-like protein 4 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 104033040 LOW QUALITY PROTEIN: DCN1-like protein 4 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 104030073 DCUN1D5; DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
D Cullin
E 104035750 CUL1; cullin-1 K03347 CUL1; cullin 1
D Adaptor protein
E 104025807 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 104035491 FBXW11; F-box/WD repeat-containing protein 11 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 104033487 BTRC; F-box/WD repeat-containing protein 1A K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 104025268 FBXW2; F-box/WD repeat-containing protein 2 K10261 FBXW2; F-box and WD-40 domain protein 2
E 104031732 FBXW5; F-box/WD repeat-containing protein 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E 104036550 FBXW7; F-box/WD repeat-containing protein 7 K10260 FBXW7; F-box and WD-40 domain protein 7
E 104028098 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 104025082 F-box/WD repeat-containing protein 10-like K10266 FBXW10; F-box and WD-40 domain protein 10
E 104030830 SKP2; S-phase kinase-associated protein 2 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 104036034 FBXL20; F-box/LRR-repeat protein 20 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 104029091 FBXL2; F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 104023751 FBXL3; F-box/LRR-repeat protein 3 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 104031551 FBXL4; F-box/LRR-repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 104025051 FBXL5; F-box/LRR-repeat protein 5 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 104030255 FBXL7; F-box/LRR-repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 104037259 FBXL8; F-box/LRR-repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 104035838 KDM2B; lysine-specific demethylase 2B K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 104038681 FBXL12; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 12 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 104032448 FBXL13; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 13 K10279 FBXL13; dynein regulatory complex subunit 6
E 104031985 FBXL14; F-box/LRR-repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 104030206 FBXL15; F-box/LRR-repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 104029856 FBXL16; LOW QUALITY PROTEIN: F-box/LRR-repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 104034154 FBXL18; F-box/LRR-repeat protein 18 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 104029105 F-box/LRR-repeat protein 21-like isoform X1 K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 104028056 FBXL22; F-box and leucine-rich protein 22 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 104039162 CCNF; cyclin-F K10289 CCNF; F-box protein 1 (cyclin F)
E 104034353 LOW QUALITY PROTEIN: F-box only protein 2-like K10099 FBXO2; F-box protein 2
E 104025353 FBXO3; F-box only protein 3 K10290 FBXO3; F-box protein 3
E 104028973 FBXO4; LOW QUALITY PROTEIN: F-box only protein 4 K10291 FBXO4; F-box protein 4
E 104034164 FBXO5; F-box only protein 5 K10292 FBXO5; F-box protein 5
E 104025631 F-box only protein 6-like K10100 FBXO6; F-box protein 6
E 104038444 FBXO7; F-box only protein 7 K10293 FBXO7; F-box protein 7
E 104025555 FBXO8; F-box only protein 8 K10294 FBXO8; F-box protein 8
E 104031198 FBXO9; F-box only protein 9 K10295 FBXO9; F-box protein 9
E 104033599 FBXO10; F-box only protein 10 K10296 FBXO10; F-box protein 10
E 104024482 FBXO11; F-box only protein 11 K10297 FBXO11; F-box protein 11
E 104024900 FBXO15; F-box only protein 15 K10298 FBXO15; F-box protein 15
E 104028986 F-box only protein 16-like K10299 FBXO16; F-box protein 16
E 104036206 FBXO18; F-box only protein 18 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 104028694 LMO7; LIM domain only protein 7 K06084 LMO7; F-box protein 20
E 104024584 FBXO21; F-box only protein 21 K10301 FBXO21; F-box protein 21
E 104027335 FBXO22; F-box only protein 22 K10302 FBXO22; F-box protein 22
E 104038873 FBXO25; F-box only protein 25 isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 104028350 FBXO32; F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E 104032760 FBXO28; F-box only protein 28 K10306 FBXO28; F-box protein 28
E 104035273 FBXO30; F-box only protein 30 K10307 FBXO30; F-box protein 30
E 104030862 FBXO31; F-box only protein 31 isoform X1 K10308 FBXO31; F-box protein 31
E 104034748 FBXO33; F-box only protein 33 K10310 FBXO33; F-box protein 33
E 104029171 FBXO34; LOW QUALITY PROTEIN: F-box only protein 34 K10311 FBXO34; F-box protein 34
E 104027409 F-box only protein 36-like K10312 FBXO36; F-box protein 36
E 104023755 FBXO38; F-box only protein 38 K10313 FBXO38; F-box protein 38
E 104034560 FBXO39; F-box only protein 39 K10314 FBXO39; F-box protein 39
E 104036391 FBXO40; LOW QUALITY PROTEIN: F-box only protein 40 K10315 FBXO40; F-box protein 40
E 104038195 FBXO42; F-box only protein 42 K10317 FBXO42; F-box protein 42
E 104023762 FBXO43; F-box only protein 43 K10318 FBXO43; F-box protein 43
E 104027406 FBXO45; F-box/SPRY domain-containing protein 1 K10319 FBXO45; F-box protein 45
E 104023926 FBXO47; F-box only protein 47 K10321 FBXO47; F-box protein 47
E 104036211 FBXO48; F-box only protein 48 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
D Cullin
E 104032728 CUL2; cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E 104026594 TCEB1; transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 104037188 TCEB2; LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E 104024773 von Hippel-Lindau disease tumor suppressor-like K03871 VHL; von Hippel-Lindau disease tumor supressor
E 104024239 LRR1; leucine-rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 104028717 FEM1C; protein fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 104026651 FEM1A; protein fem-1 homolog A K25805 FEM1A_C; protein fem-1 homolog A/C
E 104026333 FEM1B; protein fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 104036554 APPBP2; amyloid protein-binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 104032440 KLHDC2; kelch domain-containing protein 2 K25807 KLHDC2; kelch domain-containing protein 2
E 104032531 KLHDC10; kelch domain-containing protein 10 K25809 KLHDC10; kelch domain-containing protein 10
E 104024782 LOW QUALITY PROTEIN: protein zyg-11 homolog B-like K10350 ZYG11; Zyg-11 protein
E 104024960 ZER1; protein zer-1 homolog K10350 ZYG11; Zyg-11 protein
E 104036589 zinc finger SWIM domain-containing protein 8-like K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
D Cullin
E 104032730 CUL3; cullin-3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 104030780 KLHL5; kelch-like protein 5 isoform X1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 104035149 LOW QUALITY PROTEIN: kelch-like protein 4 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 104027627 KLHL3; kelch-like protein 3 K10443 KLHL2_3; kelch-like protein 2/3
E 104025099 KLHL2; kelch-like protein 2 K10443 KLHL2_3; kelch-like protein 2/3
E 104029372 KLHL6; kelch-like protein 6 K10444 KLHL6; kelch-like protein 6
E 104032716 KLHL7; kelch-like protein 7 K10445 KLHL7; kelch-like protein 7
E 104031220 KLHL8; kelch-like protein 8 isoform X1 K10446 KLHL8; kelch-like protein 8
E 104038696 kelch-like protein 13 K10447 KLHL9_13; kelch-like protein 9/13
E 104026179 LOW QUALITY PROTEIN: kelch-like protein 13 K10447 KLHL9_13; kelch-like protein 9/13
E 104032641 KLHL10; kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 104023962 KLHL11; kelch-like protein 11 K10449 KLHL11; kelch-like protein 11
E 104027502 KLHL12; kelch-like protein 12 K10450 KLHL12; kelch-like protein 12
E 104023782 kelch-like protein 15 K10452 KLHL15; kelch-like protein 15
E 104031977 GAN; gigaxonin K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 104037320 KLHL17; kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 104030989 KLHL20; kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 104028210 KLHL22; kelch-like protein 22 K10459 KLHL22; kelch-like protein 22
E 104023708 kelch-like protein 23 K10460 KLHL23; kelch-like protein 23
E 104028743 KLHL24; kelch-like protein 24 K10461 KLHL24_35; kelch-like protein 24/35
E 104032664 KLHL35; kelch-like protein 35 K10461 KLHL24_35; kelch-like protein 24/35
E 104024573 KLHL25; kelch-like protein 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 104029586 ectoderm-neural cortex protein 1-like K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 104037706 ENC1; ectoderm-neural cortex protein 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 104027150 KLHL26; kelch-like protein 26 K10463 KLHL26; kelch-like protein 26
E 104024787 IPP; actin-binding protein IPP K13956 IPP; actin-binding protein IPP
E 104031147 KLHL28; kelch-like protein 28 K10464 KLHL28; kelch-like protein 28
E 104034679 KLHL29; kelch-like protein 29 K10465 KLHL29; kelch-like protein 29
E 104035703 KLHL30; kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 104026564 LOW QUALITY PROTEIN: kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 104033161 KLHL31; kelch-like protein 31 K10467 KLHL31; kelch-like protein 31
E 104028265 KLHL32; kelch-like protein 32 isoform X1 K10468 KLHL32; kelch-like protein 32
E 104029761 KLHL33; kelch-like protein 33 K13957 KLHL33; kelch-like protein 33
E 104036372 KLHL34; kelch-like protein 34 K10469 KLHL34; kelch-like protein 34
E 104026086 KLHL36; kelch-like protein 36 K13958 KLHL36; kelch-like protein 36
E 104030148 KLHL38; kelch-like protein 38 K13959 KLHL38; kelch-like protein 38
E 104037390 KBTBD2; kelch repeat and BTB domain-containing protein 2 K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E 104025856 KBTBD3; kelch repeat and BTB domain-containing protein 3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 104025958 KBTBD4; kelch repeat and BTB domain-containing protein 4 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 104039034 KLHL41; kelch-like protein 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 104031962 KLHL40; kelch-like protein 40 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 104031908 KBTBD8; kelch repeat and BTB domain-containing protein 8 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 104027214 KBTBD12; kelch repeat and BTB domain-containing protein 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 104032991 KBTBD13; LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 13 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 104024226 BTBD2; BTB/POZ domain-containing protein 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 104033726 BTB/POZ domain-containing protein 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 104034968 BTBD3; BTB/POZ domain-containing protein 3 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 104031513 BTBD6; BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 104024564 BTBD7; BTB/POZ domain-containing protein 7 isoform X1 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 104036052 uncharacterized protein KIAA1107 homolog K10480 BTBD8; BTB/POZ domain-containing protein 8
E 104034588 BTBD9; BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 104029014 BTBD10; BTB/POZ domain-containing protein 10 isoform X1 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 104027926 ankyrin repeat and BTB/POZ domain-containing protein BTBD11-like K10483 BTBD11; BTB/POZ domain-containing protein 11
E 104026883 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 104024269 GMCL1; germ cell-less protein-like 1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 104026110 ZBTB1; zinc finger and BTB domain-containing protein 1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 104026308 ZBTB2; zinc finger and BTB domain-containing protein 2 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 104026332 ZBTB5; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 104024476 ZBTB6; zinc finger and BTB domain-containing protein 6 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 104036518 ZBTB7C; zinc finger and BTB domain-containing protein 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 104037403 ZBTB7A; zinc finger and BTB domain-containing protein 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 104037206 zinc finger and BTB domain-containing protein 8A-like K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 104033398 ZBTB8B; zinc finger and BTB domain-containing protein 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 104024472 ZBTB48; zinc finger and BTB domain-containing protein 48 isoform X1 K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 104037067 ZBTB10; zinc finger and BTB domain-containing protein 10 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 104029607 ZBTB11; zinc finger and BTB domain-containing protein 11 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 104037060 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 17-like K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 104026230 ZBTB20; zinc finger and BTB domain-containing protein 20 K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
E 104029483 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 24-like K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 104034000 ZBTB25; zinc finger and BTB domain-containing protein 25 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 104026869 ZBTB26; zinc finger and BTB domain-containing protein 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 104038043 ZBTB33; transcriptional regulator Kaiso K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 104026754 ZBTB34; zinc finger and BTB domain-containing protein 34 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E 104023869 ZBTB37; zinc finger and BTB domain-containing protein 37 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 104032273 ZBTB38; zinc finger and BTB domain-containing protein 38 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 104023714 ZBTB39; zinc finger and BTB domain-containing protein 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 104037247 ZBTB40; zinc finger and BTB domain-containing protein 40 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E 104024318 ZBTB41; zinc finger and BTB domain-containing protein 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 104024400 ZBTB43; zinc finger and BTB domain-containing protein 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 104032902 ZBTB44; zinc finger and BTB domain-containing protein 44 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 104029523 ZBTB46; zinc finger and BTB domain-containing protein 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 104026924 ZBTB47; zinc finger and BTB domain-containing protein 47 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E 104023817 zinc finger and BTB domain-containing protein 48 K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 104033512 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 104024548 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 104032602 RHOBTB1; rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 104027474 RHOBTB3; rho-related BTB domain-containing protein 3 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 104025111 KCTD10; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 104028936 TNFAIP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 104035895 KCTD1; BTB/POZ domain-containing protein KCTD1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 104026584 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 104035331 KCTD17; BTB/POZ domain-containing protein KCTD17 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 104031653 BTB/POZ domain-containing protein KCTD2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 104033247 BTB/POZ domain-containing protein KCTD5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 104034697 KCTD3; BTB/POZ domain-containing protein KCTD3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 104034216 KCTD6; BTB/POZ domain-containing protein KCTD6 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 104025798 KCTD7; BTB/POZ domain-containing protein KCTD7 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 104036012 KCTD14; BTB/POZ domain-containing protein KCTD14 isoform X1 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 104036742 KCTD16; BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 104029899 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 104027420 KCTD9; BTB/POZ domain-containing protein KCTD9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 104028930 KCTD18; BTB/POZ domain-containing protein KCTD18 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 104032462 KCTD21; BTB/POZ domain-containing protein KCTD21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 104031681 DIABLO; diablo homolog, mitochondrial K10522 DIABLO; diablo
E 104029958 SPOPL; speckle-type POZ protein-like isoform X1 K10523 SPOP; speckle-type POZ protein
E 104026926 SPOP; speckle-type POZ protein K10523 SPOP; speckle-type POZ protein
C Cul4 complex
D Ring finger protein
D Cullin
E 104035967 CUL4B; cullin-4B K10609 CUL4; cullin 4
E 104033226 CUL4A; cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E 104023757 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 104025346 DDB2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E 104027941 ERCC8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E 104038770 DET1; DET1 homolog K10571 DET1; de-etiolated-1
E 104033692 DDA1; DET1- and DDB1-associated protein 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 104037680 CRBN; protein cereblon K11793 CRBN; cereblon
E 104034543 TRPC4AP; short transient receptor potential channel 4-associated protein K11796 TRPC4AP; Trpc4-associated protein
E 104023898 VPRBP; protein VPRBP K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 104034399 DTL; denticleless protein homolog K11790 DTL; denticleless
E 104025876 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 104031812 DDB1- and CUL4-associated factor 5-like K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 104027746 DCAF7; DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 104028551 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 104038883 DCAF10; DDB1- and CUL4-associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 104031823 DCAF12; DDB1- and CUL4-associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 104038528 DDB1- and CUL4-associated factor 13-like K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 104035878 DCAF17; DDB1- and CUL4-associated factor 17 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 104038635 BRWD1; bromodomain and WD repeat-containing protein 1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 104029080 BRWD3; bromodomain and WD repeat-containing protein 3 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 104025384 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
C Cul5 complex
D Ring finger protein
E 104025743 RING-box protein 2-like K10611 RBX2; RING-box protein 2
D Cullin
E 104027421 CUL5; cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E 104026594 TCEB1; transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 104037188 TCEB2; LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E 104028138 CISH; cytokine-inducible SH2-containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 104028578 LOW QUALITY PROTEIN: suppressor of cytokine signaling 1-like K04694 SOCS1; suppressor of cytokine signaling 1
E 104029960 SOCS2; suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 104039047 SOCS4; suppressor of cytokine signaling 4 K04697 SOCS4; suppressor of cytokine signaling 4
E 104026940 SOCS5; suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 104034089 SOCS6; suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 104039211 ASB1; ankyrin repeat and SOCS box protein 1 K10323 ASB1; ankyrin repeat and SOCS box protein 1
E 104032827 LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 2-like K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 104026989 ankyrin repeat and SOCS box protein 3-like K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 104032305 ASB4; ankyrin repeat and SOCS box protein 4 isoform X1 K10326 ASB4; ankyrin repeat and SOCS box protein 4
E 104025675 ASB5; ankyrin repeat and SOCS box protein 5 isoform X1 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 104036716 ASB6; ankyrin repeat and SOCS box protein 6 isoform X1 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 104031325 ASB7; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 104024410 ASB8; ankyrin repeat and SOCS box protein 8 K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 104034982 ASB9; ankyrin repeat and SOCS box protein 9 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 104033070 ASB10; ankyrin repeat and SOCS box protein 10 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 104032511 ASB11; ankyrin repeat and SOCS box protein 11 K10333 ASB11; ankyrin repeat and SOCS box protein 11
E 104028557 ASB12; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 12 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 104031949 ASB13; ankyrin repeat and SOCS box protein 13 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 104028764 ASB14; ankyrin repeat and SOCS box protein 14 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 104033633 ASB15; ankyrin repeat and SOCS box protein 15 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 104030401 WSB1; WD repeat and SOCS box-containing protein 1 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 104031933 WSB2; WD repeat and SOCS box-containing protein 2 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 104035585 SPSB1; SPRY domain-containing SOCS box protein 1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 104028370 SPRY domain-containing SOCS box protein 1-like K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 104033451 ras-related protein Rab-40C K07928 RAB40; Ras-related protein Rab-40
E 104026364 ras-related protein Rab-40B-like K07928 RAB40; Ras-related protein Rab-40
E 104023811 LRRC41; leucine-rich repeat-containing protein 41 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 104033187 RSPRY1; RING finger and SPRY domain-containing protein 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 104025461 ankyrin repeat domain-containing protein 9-like K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 104033693 KLHDC1; kelch domain-containing protein 1 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
D Cullin
D Adaptor protein
E 104025807 SKP1; S-phase kinase-associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 104028098 FBXW8; F-box/WD repeat-containing protein 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
D Cullin
E 104033101 cullin-9-like K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
D Cullin
E 104030928 ANAPC2; anaphase-promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 104037394 CDC20; cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 104030533 FZR1; fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 104027203 CDC27; cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 104023840 ANAPC4; anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 104028775 ANAPC5; anaphase-promoting complex subunit 5 isoform X1 K03352 APC5; anaphase-promoting complex subunit 5
E 104024734 CDC16; cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 104035737 ANAPC7; anaphase-promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 104034019 CDC23; cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 104032735 ANAPC10; anaphase-promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E 104023739 ANAPC13; anaphase-promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 104026534 ANAPC16; anaphase-promoting complex subunit 16 isoform X1 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 104037885 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 104032718 BRCA2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
D 104029236 BARD1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 104031256 BRE; BRCA1-A complex subunit BRE K12173 BRE; BRCA1-A complex subunit BRE
D 104032086 RAD51; DNA repair protein RAD51 homolog 1 isoform X1 K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 104032165 RNF123; E3 ubiquitin-protein ligase RNF123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 104025135 UBAC1; ubiquitin-associated domain-containing protein 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
C CTLH complex
D 104038302 RMND5A; protein RMD5 homolog A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 104024813 RANBP9; ran-binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 104029792 ARMC8; armadillo repeat-containing protein 8 K23336 ARMC8; armadillo repeat-containing protein 8
D 104029549 muskelin-like K23337 MKLN1; muskelin
D 104032985 macrophage erythroblast attacher-like K18624 MAEA; macrophage erythroblast attacher
D 104030833 GID4; glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 104033498 GID8; glucose-induced degradation protein 8 homolog isoform X1 K23338 GID8; glucose-induced degradation protein 8
D 104026760 YPEL5; protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 104025384 WD repeat-containing protein 26 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 104024460 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 104038914 ERLIN1; erlin-1 K23341 ERLIN; erlin
D 104034404 erlin-2 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 104024460 AMFR; E3 ubiquitin-protein ligase AMFR K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 104028790 UBAC2; ubiquitin-associated domain-containing protein 2 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 104030022 CAND1; cullin-associated NEDD8-dissociated protein 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 104032242 CAND2; cullin-associated NEDD8-dissociated protein 2 K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 104031399 COMMD1; COMM domain-containing protein 1 K22557 COMMD1; COMM domain containing 1
D 104033467 COMMD2; COMM domain-containing protein 2 K22558 COMMD2; COMM domain containing 2
D 104036107 COMMD3; COMM domain-containing protein 3 K22559 COMMD3; COMM domain containing 3
D 104024211 COMMD4; COMM domain-containing protein 4 K22560 COMMD4; COMM domain containing 4
D 104025563 COMM domain-containing protein 5-like K22561 COMMD5; COMM domain containing 5
D 104024515 COMMD6; COMM domain-containing protein 6 K22562 COMMD6; COMM domain containing 6
D 104025227 COMMD7; COMM domain-containing protein 7 K22563 COMMD7; COMM domain containing 7
D 104031682 COMMD8; COMM domain-containing protein 8 K22564 COMMD8; COMM domain containing 8
D 104037648 COMMD9; COMM domain-containing protein 9 K22565 COMMD9; COMM domain containing 9
D 104038228 COMMD10; COMM domain-containing protein 10 K22566 COMMD10; COMM domain containing 10
D 104036258 DDRGK1; DDRGK domain-containing protein 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 104031238 GLMN; glomulin K23345 GLMN; glomulin
D 104028603 IVNS1ABP; influenza virus NS1A-binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 104031690 UBXN7; UBX domain-containing protein 7 K24350 UBXN7; UBX domain-containing protein 7
D 104032209 PACRG; parkin coregulated gene protein K26163 PACRG; parkin coregulated gene protein
D 104031853 parkin coregulated gene protein-like K26163 PACRG; parkin coregulated gene protein
D 104031767 UBAP2L; ubiquitin-associated protein 2-like K26545 UBAP2; ubiquitin-associated protein 2
D 104037061 ubiquitin-associated protein 2-like K26545 UBAP2; ubiquitin-associated protein 2
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 104026130 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 104027604 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 104032684 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 104034230 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 104031370 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 104027591 ubiquitin carboxyl-terminal hydrolase CYLD-like K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 104027887 USP1; ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 104033659 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 2-like K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 104028058 USP3; ubiquitin carboxyl-terminal hydrolase 3 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 104034726 USP4; ubiquitin carboxyl-terminal hydrolase 4 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 104031148 USP5; ubiquitin carboxyl-terminal hydrolase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 104030189 USP13; ubiquitin carboxyl-terminal hydrolase 13 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 104028499 USP32; ubiquitin carboxyl-terminal hydrolase 32 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 104024312 USP7; ubiquitin carboxyl-terminal hydrolase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 104033256 USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 104036664 probable ubiquitin carboxyl-terminal hydrolase FAF-X K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 104031834 USP10; ubiquitin carboxyl-terminal hydrolase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 104027017 USP12; ubiquitin carboxyl-terminal hydrolase 12 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 104036705 ubiquitin carboxyl-terminal hydrolase 12-like K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 104029360 ubiquitin carboxyl-terminal hydrolase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 104037228 USP14; ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 104027768 ubiquitin carboxyl-terminal hydrolase 15 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 104032092 USP45; ubiquitin carboxyl-terminal hydrolase 45 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 104034567 USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 104024872 USP18; ubl carboxyl-terminal hydrolase 18 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 104027763 USP19; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 19 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 104025254 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 104035460 USP20; ubiquitin carboxyl-terminal hydrolase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 104037578 ubiquitin carboxyl-terminal hydrolase 22 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 104033297 USP25; ubiquitin carboxyl-terminal hydrolase 25 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 104032825 USP37; ubiquitin carboxyl-terminal hydrolase 37 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 104028312 USP28; ubiquitin carboxyl-terminal hydrolase 28 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 104036953 USP30; ubiquitin carboxyl-terminal hydrolase 30 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 104033911 USP31; ubiquitin carboxyl-terminal hydrolase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 104036407 USP34; ubiquitin carboxyl-terminal hydrolase 34 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 104036044 USP35; ubiquitin carboxyl-terminal hydrolase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 104028275 USP38; ubiquitin carboxyl-terminal hydrolase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 104036668 USP36; ubiquitin carboxyl-terminal hydrolase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 104038590 USP42; ubiquitin carboxyl-terminal hydrolase 42 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 104038532 USP40; ubiquitin carboxyl-terminal hydrolase 40 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 104026123 USP49; ubiquitin carboxyl-terminal hydrolase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 104034935 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 104035596 USP48; ubiquitin carboxyl-terminal hydrolase 48 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
C OTU
D 104031975 OTUD3; OTU domain-containing protein 3 isoform X1 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 104033278 OTUD6B; OTU domain-containing protein 6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 104025539 OTUD7A; OTU domain-containing protein 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 104033162 TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X1 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 104025741 VCPIP1; deubiquitinating protein VCIP135 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 104032327 ZRANB1; LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 104029309 ATXN3; ataxin-3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 104037593 JOSD1; josephin-1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 104025866 FAM63B; protein FAM63B K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 104028971 FAM188B; protein FAM188B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 104025145 FAM188A; protein FAM188A K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 104031263 MYSM1; histone H2A deubiquitinase MYSM1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 104031272 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 104025001 STAMBP; STAM-binding protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D 104032039 STAMBPL1; AMSH-like protease K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 104032711 DESI2; desumoylating isopeptidase 2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 104034566 desumoylating isopeptidase 2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 104024914 ZUFSP; zinc finger with UFM1-specific peptidase domain protein K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 104036031 FAM175B; BRISC complex subunit Abro1 K20799 FAM175B; BRISC complex subunit Abro1
D 104031256 BRE; BRCA1-A complex subunit BRE K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 104037655 SENP1; sentrin-specific protease 1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 104026481 SENP2; sentrin-specific protease 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 104031621 SENP5; sentrin-specific protease 5 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 104033215 SENP6; LOW QUALITY PROTEIN: sentrin-specific protease 6 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 104032449 SENP7; sentrin-specific protease 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 104024791 SENP8; sentrin-specific protease 8 K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 104032684 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 104029797 DESI1; desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 104024101 USPL1; SUMO-specific isopeptidase USPL1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 104025248 GPS1; COP9 signalosome complex subunit 1 K12175 GPS1; COP9 signalosome complex subunit 1
D 104028325 COPS2; COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 104032650 COPS3; COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 104025094 COPS4; COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 104038980 COPS5; COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 104025594 COPS7A; COP9 signalosome complex subunit 7a K12180 COPS7; COP9 signalosome complex subunit 7
D 104025320 COPS7B; COP9 signalosome complex subunit 7b isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 104028396 COPS8; COP9 signalosome complex subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 27, 2024