+D Protein KO
#
Membrane Trafficking - Plasmodium cynomolgi
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
C Kinases and associated proteins
D PCYB_021380 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PCYB_111400 nucleoside diphosphate kinase A K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PCYB_133840 calmodulin K02183 CALM; calmodulin
D PCYB_132470 calmodulin K02183 CALM; calmodulin
D PCYB_114340 syntaxin binding protein K15292 STXBP1; syntaxin-binding protein 1
D PCYB_142960 hypothetical protein K08509 SNAP29; synaptosomal-associated protein 29
D PCYB_146700 hypothetical protein K19942 GAS8; dynein regulatory complex subunit 4
D PCYB_113310 hypothetical protein K19942 GAS8; dynein regulatory complex subunit 4
D PCYB_092050 GTPase activator protein K19953 GRTP1; TBC1 domain family member 6
D PCYB_127260 protein prenyltransferase alpha subunit K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PCYB_115390 geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PCYB_144090 geranylgeranyl transferase type2 beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
C Exocyst complex assembly proteins
D PCYB_032570 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D PCYB_041930 syntaxin K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D PCYB_146760 t-SNARE K08489 STX16; syntaxin 16
C Stx-cisGolgi
D PCYB_123070 syntaxin 5 K08490 STX5; syntaxin 5
D PCYB_131880 syntaxin 5 K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
C NPSN
D PCYB_126640 hypothetical protein K08494 NSPN; novel plant SNARE
C Gos1 (Gos28)
C Bos1 / Membrin
C Sec20
D PCYB_142610 Sec20-like protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
C STX10
C Bet1
D PCYB_082100 SNARE domain containing protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
D PCYB_142960 hypothetical protein K08509 SNAP29; synaptosomal-associated protein 29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D PCYB_141270 vesicle-associated membrane protein 714 K08515 VAMP7; vesicle-associated membrane protein 7
D PCYB_051460 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D PCYB_123810 VAMP-like protein YKT62 K08516 YKT6; synaptobrevin homolog YKT6
D PCYB_071840 prenylated protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D PCYB_082970 vesicle transport protein Sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D PCYB_114340 syntaxin binding protein K15292 STXBP1; syntaxin-binding protein 1
D PCYB_062830 vesicle transport-related protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D PCYB_092200 DHHC-type zinc finger protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCYB_114680 zinc finger protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCYB_062200 zinc finger protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCYB_101330 cell cycle regulator with zn-finger domain K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PCYB_041440 DHHC zinc finger domain containing protein K20029 ZDHHC3_7_25; palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225]
D PCYB_042720 DHHC zinc finger domain containing protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D PCYB_124030 zinc finger protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D PCYB_084620 N-ethylmaleimide sensitive fusion protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PCYB_103260 soluble NSF attachment protein K15296 NAPA; alpha-soluble NSF attachment protein
D PCYB_113810 cell division cycle protein 48 homologue K13525 VCP; transitional endoplasmic reticulum ATPase
D PCYB_011890 NSFL1 cofactor p47 K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D PCYB_144540 clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D PCYB_063120 dynamin protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D PCYB_041300 clathrin coat assembly protein AP17 K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D PCYB_052220 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D PCYB_021380 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
C Kinases
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D PCYB_063120 dynamin protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D PCYB_061520 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D PCYB_063120 dynamin protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D PCYB_122100 myosin A K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
C Kinases
D PCYB_102640 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C Phospholipase C
C Sorting nexins
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PCYB_102640 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PCYB_041390 vacuolar protein sorting-associated protein 45 K12479 VPS45; vacuolar protein sorting-associated protein 45
D PCYB_092700 DHHC zinc finger K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
D PCYB_061520 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D PCYB_124710 TLD domain-containing protein K21841 TBC1D24; TBC1 domain family member 24
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D PCYB_053420 phosphatidylinositol 3- and 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D PCYB_071100 small GTPase Rab7 K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D PCYB_091680 vacuolar sorting protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D PCYB_134970 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
D PCYB_147470 vacuolar protein sorting 26 K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C Rab associated proteins
D PCYB_102640 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PCYB_112630 20S proteasome alpha subunit D2 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PCYB_124190 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D PCYB_093780 oxysterol-binding protein/PH domain containing protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
D PCYB_127260 protein prenyltransferase alpha subunit K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PCYB_115390 geranylgeranyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PCYB_144090 geranylgeranyl transferase type2 beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D PCYB_012180 hypothetical protein K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
C ESCRT-II complex
C ESCRT-III complex
D PCYB_071400 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D PCYB_052570 SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D PCYB_146810 vacuolar sorting protein SNF7 K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D PCYB_127330 SNF7 family protein K12198 CHMP5; charged multivesicular body protein 5
D PCYB_125760 ATPase K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D PCYB_022090 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
B Tethering complex
C CORVET complex
D PCYB_104090 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PCYB_146560 Vps16-like protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D PCYB_141920 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D PCYB_074240 cacuolar protein sorting 33A K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D PCYB_104090 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D PCYB_146560 Vps16-like protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D PCYB_141920 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D PCYB_074240 cacuolar protein sorting 33A K20182 VPS33A; vacuolar protein sorting-associated protein 33A
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D PCYB_111350 S-phase kinase-associated protein 1A K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D PCYB_147490 adaptor-related protein complex 3 sigma 2 subunit K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D PCYB_121090 hypothetical protein K20195 MON1; vacuolar fusion protein MON1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D PCYB_142970 small GTPase rab11 K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D PCYB_071430 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D PCYB_145630 WD domain G-beta repeat domain containing protein K14004 SEC13; protein transport protein SEC13
C Other Rab GTPase associated proteins
D PCYB_084500 EH (for Eps15 Homology) domain containing protein K12483 EHD1; EH domain-containing protein 1
D PCYB_091440 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D PCYB_022080 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PCYB_123900 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PCYB_022190 Vps53-like protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D PCYB_101320 F-actin capping protein alpha subunit K10364 CAPZA; F-actin-capping protein subunit alpha
D PCYB_102420 f-actin capping protein beta subunit K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D PCYB_134970 vacuolar protein sorting 29 K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D PCYB_144740 hypothetical protein K23289 EIPR1; EARP and GARP complex-interacting protein 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D PCYB_095050 small GTPase Rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D PCYB_061440 roadblock/LC7 family member K10419 DYNLRB; dynein light chain roadblock-type
D PCYB_121730 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D PCYB_061520 ADP-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D PCYB_062900 ADP-ribosylation factor-like protein K07942 ARL1; ADP-ribosylation factor-like protein 1
C Arf GTPase associated proteins
D PCYB_146910 GTP-ase activating protein for Arf containing protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D PCYB_012230 GTP-ase activating protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D PCYB_114130 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
C GARP complex
D PCYB_022080 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PCYB_123900 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D PCYB_022190 Vps53-like protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C TRAPP complex II
D PCYB_135130 sybindin domain containing protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PCYB_052510 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCYB_123040 trafficking protein particle complex 2 K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCYB_053280 trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PCYB_083880 sybindin domain containing protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PCYB_132120 41-2 protein antigen precursor K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PCYB_113880 transport protein particle (TRAPP) component Bet3 K20304 TRAPPC6; trafficking protein particle complex subunit 6
D PCYB_103650 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D PCYB_146200 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D PCYB_104100 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D PCYB_125960 adapter-related protein complex 1 gamma 2 subunit K12391 AP1G1; AP-1 complex subunit gamma-1
D PCYB_101360 adapter-related protein complex 1 beta 1 subunit K12392 AP1B1; AP-1 complex subunit beta-1
D PCYB_142090 adaptor-related protein complex 1 mu 1 subunit K12393 AP1M; AP-1 complex subunit mu
D PCYB_092420 clathrin assembly protein AP19 K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D PCYB_147490 adaptor-related protein complex 3 sigma 2 subunit K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D PCYB_092560 adapter-related protein complex 4 mu 1 subunit K12402 AP4M1; AP-4 complex subunit mu-1
D PCYB_053650 adapter-related protein complex 4 sigma 1 subunit K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D PCYB_053420 phosphatidylinositol 3- and 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PCYB_021380 phosphatidylinositol-4-phosphate 5-kinase K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D PCYB_053110 small GTP-binding protein sar1 K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D PCYB_145630 WD domain G-beta repeat domain containing protein K14004 SEC13; protein transport protein SEC13
D PCYB_041610 hypothetical protein K14005 SEC31; protein transport protein SEC31
D PCYB_051860 protein transport protein Sec23A K14006 SEC23; protein transport protein SEC23
D PCYB_111950 transport protein Sec24 K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D PCYB_135130 sybindin domain containing protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PCYB_052510 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCYB_123040 trafficking protein particle complex 2 K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PCYB_053280 trafficking protein particle complex subunit 3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PCYB_083880 sybindin domain containing protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PCYB_132120 41-2 protein antigen precursor K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PCYB_113880 transport protein particle (TRAPP) component Bet3 K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D PCYB_101460 transmembrane protein K20346 TMED4_9_11; p24 family protein alpha
D PCYB_142390 cop-coated vesicle membrane protein p24 precursor K20347 TMED2; p24 family protein beta-1
D PCYB_053550 hypothetical protein K20347 TMED2; p24 family protein beta-1
D PCYB_122950 transmembrane protein Tmp21 homologue K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D PCYB_051340 protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D PCYB_094000 protein disulfide isomerase K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D PCYB_102780 small GTPase Rab1 K07874 RAB1A; Ras-related protein Rab-1A
D PCYB_102900 small GTPase Rab1A K07874 RAB1A; Ras-related protein Rab-1A
D PCYB_145670 small GTPase Rab2 K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D PCYB_121520 TBC domain containing protein K20360 TBC1D22; TBC1 domain family member 2
C ER-Golgi intermediate compartment (ERGIC) proteins
D PCYB_072550 78 kDa glucose-regulated protein precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D PCYB_114970 coatomer alpha subunit K05236 COPA; coatomer subunit alpha
D PCYB_132890 coatamer protein beta subunit K17301 COPB1; coatomer subunit beta
D PCYB_071370 coatomer complex beta subunit K17302 COPB2; coatomer subunit beta'
D PCYB_095070 coat protein gamma subunit K17267 COPG; coatomer subunit gamma
D PCYB_094070 coatomer delta subunit K20471 COPD; coatomer subunit delta
D PCYB_011880 coatomer epsilon subunit K17268 COPE; coatomer subunit epsilon
D PCYB_052850 coatomer zeta-1 subunit K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
C Golgi to ER traffic proteins (GET)
D PCYB_052810 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D PCYB_127650 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Rab GTPases
D PCYB_095050 small GTPase Rab6 K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D PCYB_112660 ER lumen protein retaining receptor K10949 KDELR; ER lumen protein retaining receptor
D PCYB_121520 TBC domain containing protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D PCYB_093780 oxysterol-binding protein/PH domain containing protein K20174 OSBPL1_2; oxysterol-binding protein-related protein 1/2
C FXYD proteins
C YIPF proteins
D PCYB_124290 hypothetical protein K20363 YIPF5_7; protein YIPF5/7
D PCYB_095230 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D PCYB_134670 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D PCYB_112040 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D PCYB_132350 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D PCYB_052740 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D PCYB_094550 hypothetical protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D PCYB_121760 protein transport protein Sec61 alpha subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PCYB_051940 protein transport protein sec61 beta 1 subunit K09481 SEC61B; protein transport protein SEC61 subunit beta
D PCYB_042000 transport protein SEC61 gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D PCYB_111830 hypothetical protein K21891 TMCO1; calcium load-activated calcium channel
D PCYB_083090 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
D PCYB_081630 hypothetical protein K26498 TMEM147; BOS complex subunit TMEM147
D PCYB_082310 hypothetical protein K26499 NCLN; BOS complex subunit NCLN
C Post-GPI attachment to proteins factors (PGAP)
C Others
D PCYB_062830 vesicle transport-related protein K19998 SCFD1; sec1 family domain-containing protein 1
D PCYB_031340 secy-independent transporter protein K20724 TMEM33; transmembrane protein 33
D PCYB_082110 hypothetical protein K21848 ARV1; lipid intermediate transporter
D PCYB_113300 hypothetical protein K22697 SAMD8; sphingomyelin synthase-related protein 1
D PCYB_134060 GTP binding protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
C Atg1 complex
C PI3K complex
D PCYB_102640 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C ATG9 transmembrane protein
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D PCYB_124500 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
C Atg8 conjugation proteins
D PCYB_061420 microtubule-associated protein 1 light chain 3 putative K08341 GABARAP; GABA(A) receptor-associated protein
D PCYB_071350 autophagocytosis associated protein C-terminal domain containing protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D PCYB_073980 aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
D PCYB_113850 hypothetical protein K19513 CLEC16A; protein CLEC16A
C Other mitophagy associated proteins
D PCYB_113380 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
B Pexophagy
C Selective cargos
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D PCYB_113810 cell division cycle protein 48 homologue K13525 VCP; transitional endoplasmic reticulum ATPase
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D PCYB_127030 fructose 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D PCYB_125230 glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PCYB_092620 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D PCYB_063070 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PCYB_113120 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PCYB_091970 ubiquitin domain containing protein K04523 UBQLN; ubiquilin
D PCYB_093800 hypothetical protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D PCYB_052220 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PCYB_011550 heat shock protein 86 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D PCYB_101400 hsp70 interacting protein K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D PCYB_112350 elongation factor 1 alpha K03231 EEF1A; elongation factor 1-alpha
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
C mTORC2 complex
C SEACIT/GATOR1 complex
C SEACAT/GATOR2 complex
D PCYB_145630 WD domain G-beta repeat domain containing protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D PCYB_102780 small GTPase Rab1 K07874 RAB1A; Ras-related protein Rab-1A
D PCYB_102900 small GTPase Rab1A K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
C Others
D PCYB_073300 protein phosphatase-beta K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PCYB_032800 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D PCYB_082270 hypothetical protein K22991 WDR45; WD repeat-containing protein 45
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D PCYB_122100 myosin A K10356 MYO1; myosin I
C Arp2/3 complex
D PCYB_092490 WD domain G-beta repeat domain containing protein K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
C Nucleation-promoting factors (NPFs)
C Others
D PCYB_111920 actin depolymerizing factor K05765 CFL; cofilin
D PCYB_103810 actin depolymerizing factor K05765 CFL; cofilin
D PCYB_021870 hypothetical protein K17261 CAP1_2; adenylyl cyclase-associated protein
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
D PCYB_011990 small GTPase Rab18 K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D PCYB_081650 Rho-GTPase-activating protein 1 K18470 ARHGAP1; Rho GTPase-activating protein 1
C Rho guanine nucleotide exchange factors (GEFs)
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2024