+F Repair protein KO
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DNA Repair and Recombination Proteins - Clostridioides difficile 630
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CDIF630_01967 ogt2; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CDIF630_00714 ogt1; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CDIF630_02728 ung; uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CDIF630_01658 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CDIF630_00312 putative 8-oxoguanine-DNA-glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CDIF630_00678 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D CDIF630_00820 mutX; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CDIF630_02645 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CDIF630_01967 ogt2; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CDIF630_00714 ogt1; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E CDIF630_02728 ung; uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CDIF630_01658 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E CDIF630_00678 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CDIF630_01497 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E CDIF630_00673 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E CDIF630_03009 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E CDIF630_03610 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E CDIF630_01275 polA; DNA polymerase I (POLI) K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CDIF630_03716 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E CDIF630_03717 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E CDIF630_03715 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E CDIF630_00456 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_01178 putative helicase, superfamily 1, UvrD-family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_00866 putative DNA helicase, UvrD / REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_00583 putative helicase, UvrD family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_01275 polA; DNA polymerase I (POLI) K02335 polA; DNA polymerase I [EC:2.7.7.7]
E CDIF630_03610 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F CDIF630_00132 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F CDIF630_00133 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F CDIF630_00168 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F CDIF630_02841 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F CDIF630_03814 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CDIF630_02182 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E CDIF630_00824 mutS2; endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
E CDIF630_02376 DNA mismatch repair protein, MutS2-like K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E CDIF630_02181 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E CDIF630_01352 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E CDIF630_01353 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E CDIF630_03701 dnaE; DNA polymerase III DnaE subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E CDIF630_01460 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E CDIF630_00002 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E CDIF630_02720 yqeN; putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E CDIF630_03864 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E CDIF630_02636 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E CDIF630_00030 dnaX; DNA polymerase III subunit gamma / tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E CDIF630_03610 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E CDIF630_00456 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_01178 putative helicase, superfamily 1, UvrD-family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_00866 putative DNA helicase, UvrD / REP type K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_00583 putative helicase, UvrD family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E CDIF630_03991 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CDIF630_03222 putative phage single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E CDIF630_01061 putative phage D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E CDIF630_00249 yrrC; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E CDIF630_01484 recA; protein RecA (Recombinase a) K03553 recA; recombination protein RecA
E CDIF630_03071 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CDIF630_03070 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CDIF630_03072 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E CDIF630_02839 priA; primosomal protein n' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E CDIF630_01183 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E CDIF630_01182 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E CDIF630_01484 recA; protein RecA (Recombinase a) K03553 recA; recombination protein RecA
E CDIF630_00089 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E CDIF630_00004 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E CDIF630_02811 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E CDIF630_03009 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E CDIF630_02678 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E CDIF630_00032 recR; recombination protein RecR K06187 recR; recombination protein RecR
E CDIF630_01358 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E CDIF630_03071 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E CDIF630_03070 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E CDIF630_03072 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E CDIF630_01181 addA; ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E CDIF630_01180 addB; ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E CDIF630_03260 putative CRISPR-associated Cas1 family protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E CDIF630_01183 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E CDIF630_01182 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F CDIF630_00006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F CDIF630_00005 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F CDIF630_01427 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F CDIF630_03809 hupA; non-specific DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F CDIF630_03009 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F CDIF630_02678 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F CDIF630_00032 recR; recombination protein RecR K06187 recR; recombination protein RecR
F CDIF630_03610 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F CDIF630_01887 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F CDIF630_03716 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F CDIF630_03717 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CDIF630_01019 dinB; DNA polymerase IV (Pol IV) K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D CDIF630_01484 recA; protein RecA (Recombinase a) K03553 recA; recombination protein RecA
D CDIF630_02135 lexA; transcriptional regulator, LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D CDIF630_01358 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D CDIF630_03991 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CDIF630_03222 putative phage single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D CDIF630_02777 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D CDIF630_01595 putative helicase, DinG family K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D CDIF630_00820 mutX; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CDIF630_02645 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CDIF630_03279 nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CDIF630_01414 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D CDIF630_03278 nrdF; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024