+F Repair protein KO
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DNA Repair and Recombination Proteins - Parascardovia denticolens
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E PSDT_0459 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PSDT_1178 putative adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PSDT_0228 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D PSDT_0580 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PSDT_0741 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E PSDT_0459 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PSDT_1178 putative adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PSDT_0228 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PSDT_0710 putative exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
E PSDT_0985 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PSDT_0825 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E PSDT_0906 excinuclease subunit A K03701 uvrA; excinuclease ABC subunit A
E PSDT_0929 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E PSDT_0824 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E PSDT_0409 putative DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_0881 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_1210 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_0985 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PSDT_1301 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F PSDT_1300 DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F PSDT_1314 DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PSDT_1298 DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F PSDT_0964 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E PSDT_0489 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E PSDT_0488 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E PSDT_0433 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E PSDT_0003 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E PSDT_0562 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E PSDT_0126 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E PSDT_0646 putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PSDT_0111 DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E PSDT_0985 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E PSDT_0409 putative DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_0881 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_1210 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSDT_0142 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E PSDT_0244 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E PSDT_1068 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
E PSDT_0074 methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E PSDT_0149 hypothetical phage protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E PSDT_1463 putative endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E PSDT_0725 recombinase RecA K03553 recA; recombination protein RecA
E PSDT_0806 holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PSDT_0805 holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PSDT_0807 holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E PSDT_1296 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E PSDT_0725 recombinase RecA K03553 recA; recombination protein RecA
E PSDT_1176 DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E PSDT_0004 recombination protein RecF K03629 recF; DNA replication and repair protein RecF
E PSDT_1456 conserved hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E PSDT_0266 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E PSDT_0416 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E PSDT_0113 recombination protein RecR K06187 recR; recombination protein RecR
E PSDT_0523 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E PSDT_0806 holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PSDT_0805 holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PSDT_0807 holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E PSDT_0389 CRISPR-associated protein K15342 cas1; CRISP-associated protein Cas1
E PSDT_1095 CRISPR-associated protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PSDT_0007 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PSDT_0737 DNA topoisomerase IV subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PSDT_0006 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F PSDT_0736 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F PSDT_0124 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F PSDT_0447 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F PSDT_0416 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F PSDT_0113 recombination protein RecR K06187 recR; recombination protein RecR
F PSDT_0985 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F PSDT_0825 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F PSDT_0906 excinuclease subunit A K03701 uvrA; excinuclease ABC subunit A
F PSDT_0929 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D PSDT_1232 putative DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D PSDT_0945 putative DNA polymerase K03502 umuC; DNA polymerase V
D PSDT_0944 putative SOS mutagenesis protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D PSDT_0725 recombinase RecA K03553 recA; recombination protein RecA
D PSDT_0623 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D PSDT_0523 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D PSDT_0142 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D PSDT_0244 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D PSDT_1068 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein
D PSDT_0726 putative regulatory protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D PSDT_0892 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D PSDT_0580 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PSDT_0098 conserved hypothetical protein K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D PSDT_0741 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024