+D Protein KO
#
Membrane Trafficking - Penicillium digitatum
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
D PDIP_33610 hypothetical protein K28063 ESYT; extended synaptotagmin
D PDIP_55890 hypothetical protein K28063 ESYT; extended synaptotagmin
C Septins
D PDIP_54680 hypothetical protein K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D PDIP_74590 Serine/threonine protein kinase, putative K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D PDIP_26340 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D PDIP_01310 Phospholipase D1 (PLD1), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PDIP_37670 Phospholipase D (PLD), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PDIP_47420 Phospholipase PldA, putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D PDIP_00910 Multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PDIP_80070 Serine/threonine-protein kinase ste20 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D PDIP_48130 Mst3-like protein kinase, putative K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D PDIP_82330 Ste20-like serine/threonine protein kinase, putative K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D PDIP_48830 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D PDIP_30360 Serine/threonine protein kinase Kin1, putative K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D PDIP_46510 Calcium sensor (NCS-1), putative K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D PDIP_14740 Rab GTPase SrgA, putative K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D PDIP_25360 Calmodulin K02183 CALM; calmodulin
D PDIP_00700 GDP/GTP exchange factor Sec2p, putative K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D PDIP_57420 Sec1 family superfamily K15292 STXBP1; syntaxin-binding protein 1
D PDIP_30030 SNARE-dependent exocytosis protein (Sro7), putative K08518 STXBP5; syntaxin-binding protein 5
D PDIP_52440 Phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PDIP_52920 GTPase activating protein (Gyp2), putative K19951 TBC1D8_9; TBC1 domain family member 8/9
D PDIP_03870 Peroxin-5 K13342 PEX5; peroxin-5
D PDIP_62210 Rab geranylgeranyl transferase escort protein, putative K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PDIP_32930 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PDIP_58320 Rab geranylgeranyltransferase, beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PDIP_67420 WD repeat protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D PDIP_86770 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
D PDIP_00590 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D PDIP_20880 Exocyst complex component Sec3, putative K19983 EXOC1; exocyst complex component 1
D PDIP_28160 hypothetical protein K17637 EXOC2; exocyst complex component 2
D PDIP_24770 Sec6p K06110 EXOC3; exocyst complex component 3
D PDIP_52250 Exocyst complex component Sec8, putative K06111 EXOC4; exocyst complex component 4
D PDIP_42210 Exocyst complex component Sec10, putative K19984 EXOC5; exocyst complex component 5
D PDIP_18900 Exocyst complex component Sec15, putative K19985 EXOC6; exocyst complex component 6
D PDIP_31970 Exocyst complex protein exo70 K07195 EXOC7; exocyst complex component 7
D PDIP_39770 Exocyst complex component exo84 K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D PDIP_06110 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D PDIP_82470 Tropomyosin, putative K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D PDIP_61850 Chitin biosynthesis protein (Chs5), putative K19877 CHS5; chitin biosynthesis protein CHS5
D PDIP_74460 Clathrin-coated vesiclec protein (Bud7), putative K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D PDIP_23980 Vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D PDIP_51270 Phosphatidylinositol transfer protein SFH5 K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D PDIP_55390 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D PDIP_25370 SNARE complex subunit (Tlg2), putative K08489 STX16; syntaxin 16
C Stx-cisGolgi
D PDIP_10000 ER-Golgi SNARE complex subunit (Sed5), putative K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D PDIP_33040 Vti1p K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D PDIP_31450 Vesicle transport v-SNARE protein Gos1, putative K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D PDIP_47500 Bos1, putative K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
C STX8
D PDIP_80690 SNARE complex subunit (Syn8), putative K08501 STX8; syntaxin 8
D PDIP_75580 SNARE complex subunit (Vam7), putative K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D PDIP_36920 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D PDIP_78860 Plasma membrane SNARE protein (Sec9), putative K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D PDIP_62290 V-SNARE, putative K08513 VAMP4; vesicle-associated membrane protein 4
D PDIP_39730 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D PDIP_77490 SNARE protein Ykt6, putative K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D PDIP_17370 Protein transport protein sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D PDIP_30030 SNARE-dependent exocytosis protein (Sro7), putative K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D PDIP_57420 Sec1 family superfamily K15292 STXBP1; syntaxin-binding protein 1
D PDIP_23960 Golgi transport protein Sly1, putative K19998 SCFD1; sec1 family domain-containing protein 1
D PDIP_87460 hypothetical protein K26808 TXLN; taxilin
C Palmitoyltransferases
D PDIP_37630 Palmitoyltransferase pfa3 K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D PDIP_36420 Palmitoyltransferase swf1 K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D PDIP_14410 Palmitoyltransferase akr1 K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D PDIP_29380 NsfA K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D PDIP_35370 hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D PDIP_44580 Atg24p K17919 SNX4; sorting nexin-4
D PDIP_78370 Sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D PDIP_72670 hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D PDIP_38040 Cdc48p K13525 VCP; transitional endoplasmic reticulum ATPase
D PDIP_48410 Cdc48-dependent protein degradation adaptor protein (Shp1), putative K14012 NSFL1C; UBX domain-containing protein 1
D PDIP_20080 Protein vts1 K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D PDIP_16190 Clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D PDIP_42060 Dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D PDIP_15660 AP-2 adaptor complex subunit alpha, putative K11824 AP2A; AP-2 complex subunit alpha
D PDIP_64230 AP-2 adaptor complex subunit beta, putative K11825 AP2B1; AP-2 complex subunit beta-1
D PDIP_52390 AP-2 adaptor complex subunit mu, putative K11826 AP2M1; AP-2 complex subunit mu-1
C Other core components
D PDIP_26750 hypothetical protein K20042 FCHO; F-BAR domain only protein
D PDIP_43320 hypothetical protein K12471 EPN; epsin
D PDIP_71130 Golgi to endosome transport protein (Ent3), putative K12471 EPN; epsin
D PDIP_63470 hypothetical protein K12472 EPS15; epidermal growth factor receptor substrate 15
D PDIP_70360 hypothetical protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D PDIP_24490 BAR adaptor protein, putative K12562 AMPH; amphiphysin
D PDIP_01950 Cytoskeleton assembly control protein Sla1, putative K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D PDIP_82950 Actin cytoskeleton-regulatory complex protein PAN1 K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D PDIP_27890 Cytoskeletal adaptor protein SagA K20048 END3; actin cytoskeleton-regulatory complex protein END3
D PDIP_26120 Heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PDIP_85580 Heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D PDIP_00910 Multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D PDIP_82270 hypothetical protein K20059 LDB19; arrestin-related trafficking adapter 1
D PDIP_76750 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D PDIP_03390 hypothetical protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D PDIP_36930 HECT-type ubiquitin ligase-interacting protein creD K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D PDIP_71710 PH response protein PalF K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D PDIP_52440 Phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PDIP_01760 hypothetical protein K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D PDIP_69500 Serine/threonine protein kinase, putative K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D PDIP_21740 Protein kinase Scy1, putative K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D PDIP_41020 E3 ubiquitin--protein ligase pub1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D PDIP_00850 Cytoskeleton assembly control protein Sla2, putative K20040 HIP1R; huntingtin-interacting protein 1-related protein
D PDIP_44680 hypothetical protein K08054 CANX; calnexin
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D PDIP_42060 Dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D PDIP_59840 Protein kinase K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D PDIP_86770 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
D PDIP_28470 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D PDIP_75440 ADP-ribosylation factor 6, putative K07941 ARF6; ADP-ribosylation factor 6
D PDIP_00590 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D PDIP_68740 Rho GTPase Rho1 K04513 RHOA; Ras homolog gene family, member A
D PDIP_42060 Dynamin-like GTPase Dnm1, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D PDIP_03310 Myosin I MyoA/Myo5 K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D PDIP_14290 Ras small monomeric GTPase RasB K07827 KRAS; GTPase KRas
D PDIP_60730 RAS protein K07827 KRAS; GTPase KRas
D PDIP_00590 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D PDIP_86770 Rho GTPase ModA, putative K04393 CDC42; cell division control protein 42
C Kinases
D PDIP_51620 Vps34p K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PDIP_70550 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D PDIP_80070 Serine/threonine-protein kinase ste20 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
D PDIP_26340 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D PDIP_44700 Vacuolar protein sorting-associated protein Vps5, putative K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D PDIP_24490 BAR adaptor protein, putative K12562 AMPH; amphiphysin
D PDIP_22640 hypothetical protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D PDIP_07040 hypothetical protein K20121 FNBP1; formin-binding protein 1
D PDIP_26750 hypothetical protein K20042 FCHO; F-BAR domain only protein
D PDIP_00570 Rho GTPase activator (Rgd1), putative K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D PDIP_87580 RAB GTPase Ypt5, putative K07888 RAB5B; Ras-related protein Rab-5B
C Rab associated proteins
D PDIP_34280 Guanine nucleotide exchange factor Vps9, putative K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D PDIP_23980 Vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D PDIP_52440 Phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PDIP_51620 Vps34p K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PDIP_39610 Vps15p K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PDIP_18450 Vacuolar protein sorting-associated protein VpsB K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D PDIP_28470 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D PDIP_75440 ADP-ribosylation factor 6, putative K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D PDIP_36790 Stromal membrane-associated protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D PDIP_01840 Phosphatidylinositol 4-kinase (STT4), putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PDIP_24250 hypothetical protein K21842 EFR3; protein EFR3
D PDIP_49890 Filamentation protein (Rhf1), putative K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D PDIP_87580 RAB GTPase Ypt5, putative K07888 RAB5B; Ras-related protein Rab-5B
D PDIP_59530 Rab small monomeric GTPase Rab7, putative K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D PDIP_29230 Vacuolar sorting protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D PDIP_41000 Vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
D PDIP_86070 Vacuolar protein sorting-associated protein 26, putative K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D PDIP_34680 Microtubule binding protein HOOK3, putative K16536 HOOK3; protein HOOK3
C FERRY complex
C Rab associated proteins
D PDIP_51620 Vps34p K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PDIP_48050 Proteasome component Pre6, putative K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D PDIP_70120 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D PDIP_17170 hypothetical protein K20168 TBC1D15; TBC1 domain family member 15
D PDIP_62210 Rab geranylgeranyl transferase escort protein, putative K23460 CHM; Rab proteins geranylgeranyltransferase component A
D PDIP_32930 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D PDIP_58320 Rab geranylgeranyltransferase, beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D PDIP_39650 hypothetical protein K20176 SGSM3; small G protein signaling modulator 3
D PDIP_72670 hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D PDIP_32600 hypothetical protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D PDIP_76470 Acetyltransferase, GNAT family, putative K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D PDIP_19390 Amino-acid N-acetyltransferase subunit Mak10, putative K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D PDIP_70210 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D PDIP_80130 Vacuolar sorting-associated protein (Vps27), putative K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D PDIP_80060 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D PDIP_24470 Endosomal sorting complex protein, putative K12183 TSG101; ESCRT-I complex subunit TSG101
D PDIP_11400 Vacuolar protein sorting-associated protein Vps28, putative K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D PDIP_15060 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D PDIP_85820 ESCRT-II complex component (Vps25), putative K12189 VPS25; ESCRT-II complex subunit VPS25
D PDIP_15370 Vacuolar protein sorting protein (Vps36), putative K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D PDIP_81950 SNF7 family protein K12191 CHMP2A; charged multivesicular body protein 2A
D PDIP_81620 hypothetical protein K12193 VPS24; charged multivesicular body protein 3
D PDIP_69310 SNF7 family protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D PDIP_33330 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D PDIP_41360 SNF7 family protein K12195 CHMP6; charged multivesicular body protein 6
D PDIP_37820 Vacuolar sorting protein SNF7 family protein, putative K15053 CHMP7; charged multivesicular body protein 7
D PDIP_76010 Vacuolar sorting ATPase Vps4, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D PDIP_84000 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D PDIP_14000 PH signal transduction protein PalA, putative K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D PDIP_66830 TGF beta receptor associated protein 1, putative K20177 VPS3; vacuolar protein sorting-associated protein 3
D PDIP_84110 Golgi complex component (Vps8), putative K20178 VPS8; vacuolar protein sorting-associated protein 8
D PDIP_38520 Vacuolar protein sorting protein (VPS11), putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D PDIP_81730 Vacuolar protein sorting vps16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D PDIP_50000 Vacuolar protein sorting protein DigA K20181 VPS18; vacuolar protein sorting-associated protein 18
D PDIP_78850 Vacuolar sorting protein, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D PDIP_38520 Vacuolar protein sorting protein (VPS11), putative K20179 VPS11; vacuolar protein sorting-associated protein 11
D PDIP_81730 Vacuolar protein sorting vps16, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D PDIP_50000 Vacuolar protein sorting protein DigA K20181 VPS18; vacuolar protein sorting-associated protein 18
D PDIP_78850 Vacuolar sorting protein, putative K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D PDIP_47570 Vacuolar morphogenesis protein AvaB, putative K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D PDIP_29830 Vacuolar assembly protein, putative K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D PDIP_67420 WD repeat protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D PDIP_67420 WD repeat protein K24155 DMXL; rabconnectin-3a
D PDIP_22760 E3 ubiquitin ligase complex SCF subunit sconC K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D PDIP_01730 AP-3 complex subunit delta, putative K12396 AP3D; AP-3 complex subunit delta
D PDIP_60500 AP-3 adaptor complex subunit beta, putative K12397 AP3B; AP-3 complex subunit beta
D PDIP_43950 AP-3 adaptor complex subunit mu, putative K12398 AP3M; AP-3 complex subunit mu
D PDIP_45240 AP-3 adaptor complex subunit sigma, putative K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D PDIP_29390 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Lysosomal membrane proteins
D PDIP_88930 hypothetical protein K14617 LMBRD1; LMBR1 domain-containing protein 1
C Others
D PDIP_37480 Vacuolar fusion protein mon1 K20195 MON1; vacuolar fusion protein MON1
D PDIP_80120 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PDIP_08680 Endosome-associated ubiquitin isopeptidase (AmsH), putative K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D PDIP_18240 Vacuolar protein sorting 55 superfamily K28212 LEPROT; OB-RGRP/VPS55 family protein
D PDIP_48240 Vacuolar dynamin-like GTPase VpsA, putative K23481 VPS1; vacuolar protein sorting-associated protein 1
D PDIP_49690 hypothetical protein K24781 BPH1; beige protein homolog 1
D PDIP_85310 Phospholipid metabolism enzyme regulator, putative K28440 VAC7; vacuolar segregation protein 7
D PDIP_12810 hypothetical protein K28441 TAG1; protein TAG1
D PDIP_65940 hypothetical protein K28544 SSH4; SSH4 family protein
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D PDIP_56640 hypothetical protein K07880 RAB4B; Ras-related protein Rab-4B
D PDIP_63160 GTP-binding protein yptV1 K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D PDIP_23980 Vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D PDIP_44580 Atg24p K17919 SNX4; sorting nexin-4
D PDIP_51800 Dynein family protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D PDIP_59340 WD repeat protein K20241 WDR44; WD repeat-containing protein 44
D PDIP_21810 Nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
D PDIP_18900 Exocyst complex component Sec15, putative K19985 EXOC6; exocyst complex component 6
D PDIP_72670 hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D PDIP_52440 Phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PDIP_34280 Guanine nucleotide exchange factor Vps9, putative K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D PDIP_06050 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D PDIP_08580 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PDIP_21180 GARP complex subunit (Sac2), putative K20298 VPS52; vacuolar protein sorting-associated protein 52
D PDIP_19940 GARP complex subunit Vps53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D PDIP_47220 F-actin capping protein alpha subunit, putative K10364 CAPZA; F-actin-capping protein subunit alpha
D PDIP_83510 F-actin capping protein beta subunit K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D PDIP_41000 Vacuolar protein sorting 29, putative K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D PDIP_79140 Fermentation associated protein (Csf1), putative K24964 BLTP1; Bridge-like lipid transfer protein family member 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D PDIP_72670 hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D PDIP_52920 GTPase activating protein (Gyp2), putative K19951 TBC1D8_9; TBC1 domain family member 8/9
D PDIP_31230 M protein repeat protein K20286 TMF1; TATA element modulatory factor
D PDIP_79170 Dynactin, putative K04648 DCTN1; dynactin 1
D PDIP_52440 Phosphatase family protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D PDIP_33900 Vacuolar protein sorting-associated protein vps13 K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D PDIP_28470 hypothetical protein K07937 ARF1_2; ADP-ribosylation factor 1/2
D PDIP_63670 ADP-ribosylation factor, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
D PDIP_11770 ADP-ribosylation factor family protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D PDIP_50830 Zinc finger protein gcs1 K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D PDIP_64970 ARF GTPase activator (Glo3), putative K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D PDIP_36790 Stromal membrane-associated protein K12486 SMAP; stromal membrane-associated protein
D PDIP_01880 ARF GTPase activator (Csx2), putative K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D PDIP_47470 Guanyl-nucleotide exchange factor (Sec7), putative K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D PDIP_59930 Guanine nucleotide exchange factor (Gea2), putative K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D PDIP_17450 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D PDIP_48700 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D PDIP_29980 Golgi complex component Cog3, putative K20290 COG3; conserved oligomeric Golgi complex subunit 3
D PDIP_87280 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D PDIP_43480 Golgi transport complex subunit Cog6, putative K20293 COG6; conserved oligomeric Golgi complex subunit 6
D PDIP_76560 Dor1-like family protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D PDIP_08580 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D PDIP_21180 GARP complex subunit (Sac2), putative K20298 VPS52; vacuolar protein sorting-associated protein 52
D PDIP_19940 GARP complex subunit Vps53, putative K20299 VPS53; vacuolar protein sorting-associated protein 53
D PDIP_48640 GARP complex component (Vps54), putative K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D PDIP_22660 TRAPP complex subunit (Bet5), putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PDIP_22080 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PDIP_84460 Trafficking protein particle complex subunit 2/Sedlin, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PDIP_56440 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PDIP_04800 Sybindin-like family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PDIP_58550 BET3 family protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PDIP_18960 BET3 family protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D PDIP_37860 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D PDIP_18300 Hypercellular protein HypA K20306 TRAPPC9; trafficking protein particle complex subunit 9
D PDIP_27190 TMEM1 family protein, putative K20307 TRAPPC10; trafficking protein particle complex subunit 10
D PDIP_41540 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D PDIP_29010 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D PDIP_13810 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D PDIP_69730 AP-1 adaptor complex subunit gamma, putative K12391 AP1G1; AP-1 complex subunit gamma-1
D PDIP_08430 AP-1 adaptor complex subunit beta, putative K12392 AP1B1; AP-1 complex subunit beta-1
D PDIP_53410 AP-1 adaptor complex subunit mu, putative K12393 AP1M; AP-1 complex subunit mu
D PDIP_07280 AP-1 adaptor complex subunit sigma, putative K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D PDIP_01730 AP-3 complex subunit delta, putative K12396 AP3D; AP-3 complex subunit delta
D PDIP_60500 AP-3 adaptor complex subunit beta, putative K12397 AP3B; AP-3 complex subunit beta
D PDIP_43950 AP-3 adaptor complex subunit mu, putative K12398 AP3M; AP-3 complex subunit mu
D PDIP_45240 AP-3 adaptor complex subunit sigma, putative K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D PDIP_72620 hypothetical protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D PDIP_17420 hypothetical protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D PDIP_01310 Phospholipase D1 (PLD1), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PDIP_37670 Phospholipase D (PLD), putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PDIP_47420 Phospholipase PldA, putative K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D PDIP_01840 Phosphatidylinositol 4-kinase (STT4), putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D PDIP_00910 Multicopy suppressor of stt4 mutation K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D PDIP_70550 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D PDIP_72140 hypothetical protein K20316 SCOC; short coiled-coil protein
D PDIP_76290 hypothetical protein K20318 SYS1; protein SYS1
D PDIP_09570 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D PDIP_75900 hypothetical protein K23542 TMEM199; TMEM199 family protein
D PDIP_00780 hypothetical protein K23543 CCDC115; coiled-coil domain-containing protein 115
D PDIP_79280 Membrane protein TMS1, putative K23544 SERINC1; serine incorporator 1
D PDIP_09390 Sorting nexin-3 K17918 SNX3_12; sorting nexin-3/12
D PDIP_38540 Sorting nexin mvp1 K17922 SNX8; sorting nexin-8
D PDIP_86060 Endosomal peripheral membrane protein (Mon2), putative K26678 MON2; protein MON2
D PDIP_37470 Cellular morphogenesis regulator DopA K26680 DOP1; protein dopey
D PDIP_53260 hypothetical protein K27894 HID1; protein HID1
D PDIP_60910 COPI-coated vesicle protein, putative K26750 TVP15; golgi apparatus membrane protein TVP15
D PDIP_29290 Clathrin-coated vesicle protein, putative K26751 TVP18; golgi apparatus membrane protein TVP18
D PDIP_44500 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
D PDIP_44530 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D PDIP_48240 Vacuolar dynamin-like GTPase VpsA, putative K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D PDIP_20160 GTP-binding protein sarA K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D PDIP_21810 Nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
D PDIP_35190 Protein transport protein (SEC31), putative K14005 SEC31; protein transport protein SEC31
D PDIP_83940 Protein transport protein Sec23, putative K14006 SEC23; protein transport protein SEC23
D PDIP_45470 Protein transport protein Sec24, putative K14007 SEC24; protein transport protein SEC24
D PDIP_76200 Sec23/Sec24 family protein K14007 SEC24; protein transport protein SEC24
D PDIP_17220 COPII vesicle coat protein Sec16, putative K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D PDIP_22660 TRAPP complex subunit (Bet5), putative K20300 TRAPPC1; trafficking protein particle complex subunit 1
D PDIP_22080 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PDIP_84460 Trafficking protein particle complex subunit 2/Sedlin, putative K20301 TRAPPC2; trafficking protein particle complex subunit 2
D PDIP_56440 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D PDIP_04800 Sybindin-like family protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D PDIP_58550 BET3 family protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D PDIP_18960 BET3 family protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D PDIP_12530 hypothetical protein K20346 TMED4_9_11; p24 family protein alpha
D PDIP_30590 Endosomal cargo receptor (P24), putative K20347 TMED2; p24 family protein beta-1
D PDIP_44380 Endosomal cargo receptor (Erv25), putative K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D PDIP_56880 Protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D PDIP_59400 Protein disulfide-isomerase tigA K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D PDIP_84070 PDI related protein A K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
C Rab associated proteins
D PDIP_68410 COPII vesicles protein Yip3, putative K20359 RABAC1; PRA1 family protein 1
D PDIP_68420 hypothetical protein K20359 RABAC1; PRA1 family protein 1
D PDIP_21220 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D PDIP_32440 GTPase activating protein (Gyp1), putative K20360 TBC1D22; TBC1 domain family member 2
D PDIP_17120 ER to Golgi transport protein Yif1 K20362 YIF1; protein transport protein YIF1
D PDIP_44630 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
D PDIP_67380 Transport protein, putative K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D PDIP_37970 hypothetical protein K10080 LMAN1; lectin, mannose-binding 1
D PDIP_89440 Lectin family integral membrane protein, putative K10082 LMAN2; lectin, mannose-binding 2
D PDIP_25340 Class I alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D PDIP_43660 Class I alpha-mannosidase 1A K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D PDIP_66420 Mannosyl-oligosaccharide 1,2-alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D PDIP_72360 putative class I alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D PDIP_68610 Mannosyl-oligosaccharide alpha-1,2-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D PDIP_07310 COPII-coated vesicle protein (Erv41), putative K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D PDIP_19930 COPII-coated vesicle membrane protein Erv46, putative K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D PDIP_70800 hypothetical protein K20368 CNIH; protein cornichon
D PDIP_28400 COPII-coated vesicle protein SurF4/Erv29, putative K20369 ERV29; ER-derived vesicles protein
D PDIP_80020 hypothetical protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D PDIP_08460 hypothetical protein K05236 COPA; coatomer subunit alpha
D PDIP_27480 Coatomer subunit beta, putative K17301 COPB1; coatomer subunit beta
D PDIP_64040 COPI vesicle coat beta' subunit, putative K17302 COPB2; coatomer subunit beta'
D PDIP_75630 Coatomer subunit gamma K17267 COPG; coatomer subunit gamma
D PDIP_65640 Coatomer subunit delta, putative K20471 COPD; coatomer subunit delta
D PDIP_27620 Coatomer subunit epsilon, putative K17268 COPE; coatomer subunit epsilon
D PDIP_19550 Coatomer subunit zeta, putative K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D PDIP_29940 RINT-1 family protein K20474 RINT1; RAD50-interacting protein 1
D PDIP_12290 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D PDIP_69570 Protein transport protein Sec39, putative K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D PDIP_14100 Protein get1 K22384 GET1; tail-anchored protein insertion receptor
D PDIP_33470 hypothetical protein K22386 GET2; GET complex subunit GET2
D PDIP_29690 ATPase GET3 K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D PDIP_18710 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
D PDIP_47670 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
C Rab associated proteins
D PDIP_40070 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D PDIP_89260 Intracellular protein transport protein (Sat1), putative K20477 RGP1; RAB6A-GEF complex partner protein 2
D PDIP_26260 ER lumen protein retaining receptor K10949 KDELR; ER lumen protein retaining receptor
D PDIP_23980 Vacuolar segregation protein (Pep7), putative K12481 RBSN; rabenosyn-5
D PDIP_32440 GTPase activating protein (Gyp1), putative K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D PDIP_56600 Oxysterol binding protein (Osh1), putative K20456 OSBP; oxysterol-binding protein 1
D PDIP_01120 Oxysterol binding protein (Osh3), putative K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D PDIP_71240 Oxysterol binding protein (Osh7), putative K22285 OSBPL8; oxysterol-binding protein-related protein 8
D PDIP_01220 Oxysterol binding protein (Orp8), putative K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D PDIP_74340 hypothetical protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D PDIP_21210 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D PDIP_14930 Golgi membrane protein, putative K20363 YIPF5_7; protein YIPF5/7
D PDIP_63840 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D PDIP_49610 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D PDIP_01720 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D PDIP_03770 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D PDIP_64240 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D PDIP_30490 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D PDIP_20070 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D PDIP_26130 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
C SEC61 complex
D PDIP_52180 Protein transport protein Sec61 alpha subunit, putative K10956 SEC61A; protein transport protein SEC61 subunit alpha
D PDIP_20290 Translocon protein Sec61beta, putative K09481 SEC61B; protein transport protein SEC61 subunit beta
D PDIP_09410 Protein translocation complex subunit Sss1, putative K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D PDIP_25450 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D PDIP_54330 GPI inositol-deacylase K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D PDIP_69180 Mn2+ homeostasis protein (Per1), putative K23553 PGAP3; post-GPI attachment to proteins factor 3
D PDIP_03080 Manganese ion homeostasis (Fr), putative K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D PDIP_72230 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D PDIP_23960 Golgi transport protein Sly1, putative K19998 SCFD1; sec1 family domain-containing protein 1
D PDIP_54630 hypothetical protein K20724 TMEM33; transmembrane protein 33
D PDIP_10980 hypothetical protein K21848 ARV1; lipid intermediate transporter
D PDIP_31920 Beta-1,6 glucan synthetase (Kre6), putative K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D PDIP_72670 hypothetical protein K15620 GOLPH3; golgi phosphoprotein 3
D PDIP_12240 hypothetical protein K26681 INSIG; insulin-induced protein
D PDIP_77540 Got1 family protein K26683 GOLT1; vesicle transport protein GOT1
D PDIP_76900 Protein sey1 K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D PDIP_80200 Autophagy protein Atg13, putative K08331 ATG13; autophagy-related protein 13
D PDIP_51340 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D PDIP_72530 Serine/threonine protein kinase (Pdd7p), putative K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D PDIP_80200 Autophagy protein Atg13, putative K08331 ATG13; autophagy-related protein 13
D PDIP_78420 Kinase activator (Atg17), putative K08329 ATG17; autophagy-related protein 17
C PI3K complex
D PDIP_51620 Vps34p K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D PDIP_39610 Vps15p K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D PDIP_03940 Atg6p K08334 BECN; beclin
C ATG9 transmembrane protein
D PDIP_43640 Autophagy protein Apg9, putative K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D PDIP_60140 Protein-vacuolar targeting protein Atg18, putative K17908 WIPI1_2; autophagy-related protein 18
D PDIP_45000 Autophagy regulatory protein Atg2, putative K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D PDIP_35590 Ubiquitin-like protein ATG12 K08336 ATG12; ubiquitin-like protein ATG12
D PDIP_56790 Autophagy ubiquitin-activating enzyme ApgG, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PDIP_68260 Atg10p K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D PDIP_71780 Autophagy protein 5 K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D PDIP_34700 Autophagy-related protein 8 K08341 GABARAP; GABA(A) receptor-associated protein
D PDIP_01630 Autophagy cysteine endopeptidase Atg4, putative K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D PDIP_56790 Autophagy ubiquitin-activating enzyme ApgG, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D PDIP_52150 Autophagy-related protein 3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D PDIP_53680 Vacuolar aspartyl aminopeptidase Lap4, putative K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D PDIP_00080 Alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D PDIP_00190 Aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D PDIP_30270 Atg11p K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D PDIP_78370 Sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D PDIP_44580 Atg24p K17919 SNX4; sorting nexin-4
D PDIP_63750 Autophagy related lipase Atg15, putative K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D PDIP_05640 Atg27p K21141 ATG27; autophagy-related protein 27
D PDIP_81780 Vac8p K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D PDIP_30270 Atg11p K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D PDIP_81960 Transmembrane GTPase Fzo1, putative K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D PDIP_01180 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D PDIP_17200 Hexokinase, putative K00844 HK; hexokinase [EC:2.7.1.1]
D PDIP_62070 Glucokinase GlkA, putative K00844 HK; hexokinase [EC:2.7.1.1]
D PDIP_82720 Hexokinase-1 K00844 HK; hexokinase [EC:2.7.1.1]
D PDIP_87300 Hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
D PDIP_72170 Mitochondrial ATPase inhibitor, putative K22255 ATPIF1; ATPase inhibitor, mitochondrial
D PDIP_52880 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D PDIP_51330 Peroxin 3 K13336 PEX3; peroxin-3
D PDIP_28820 Peroxisomal membrane anchor protein (Pex14), putative K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D PDIP_01180 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
D PDIP_64550 Peroxin-1 K13338 PEX1; peroxin-1
D PDIP_06770 Peroxisomal biogenesis factor 6 K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D PDIP_01180 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D PDIP_38040 Cdc48p K13525 VCP; transitional endoplasmic reticulum ATPase
D PDIP_47880 Histone deacetylase HdaA K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D PDIP_63620 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
D PDIP_01180 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B ER-phagy
C ER-phagy recepters
D PDIP_89040 Translocation protein Sec62, putative K12275 SEC62; translocation protein SEC62
C Other ER-phagy associated proteins
D PDIP_44680 hypothetical protein K08054 CANX; calnexin
D PDIP_28920 DNA damage response protein (Dap1), putative K17278 PGRMC1_2; membrane-associated progesterone receptor component
C ER stress-related proteins
D PDIP_80020 hypothetical protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D PDIP_23830 Translation initiation factor 2 alpha subunit, putative K03237 EIF2S1; translation initiation factor 2 subunit 1
B Chaperone mediated autophagy (CMA)
C Selective cargos
D PDIP_40710 hypothetical protein K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D PDIP_61860 Aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D PDIP_65080 Aspartate transaminase, putative K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D PDIP_47870 Glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D PDIP_70570 Pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D PDIP_45930 Ubiquitin-like protein DskB, putative K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D PDIP_26120 Heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PDIP_85580 Heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D PDIP_54950 Heat shock protein 90 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D PDIP_69010 Elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D PDIP_46070 Carboxypeptidase Y, putative K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D PDIP_81780 Vac8p K08332 VAC8; vacuolar protein 8
C Midbophagy
D PDIP_01180 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D PDIP_81960 Transmembrane GTPase Fzo1, putative K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D PDIP_64280 Tor K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PDIP_40640 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D PDIP_75690 TORC1 growth control complex subunit Kog1, putative K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D PDIP_64280 Tor K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D PDIP_40640 hypothetical protein K08266 MLST8; target of rapamycin complex subunit LST8
D PDIP_89400 Stress activated MAP kinase interacting protein, putative K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D PDIP_64160 Cytosolic regulator Pianissimo, putative K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
D PDIP_86600 Vacuolar membrane-associated protein iml1 K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D PDIP_20620 Nitrogen permease regulator Npr2, putative K20405 NPRL2; nitrogen permease regulator 2
D PDIP_40260 hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D PDIP_71950 WD repeat protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D PDIP_61920 WD repeat protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D PDIP_70070 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D PDIP_10710 Nuclear pore protein (SEH1), putative K14299 SEH1; nucleoporin SEH1
D PDIP_21810 Nuclear pore complex subunit (SEC13), putative K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D PDIP_14740 Rab GTPase SrgA, putative K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D PDIP_39130 Serine/threonine-protein phosphatase K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D PDIP_60060 hypothetical protein K17606 IGBP1; immunoglobulin-binding protein 1
D PDIP_82040 UV radiation resistance protein (UVRAG), putative K21249 UVRAG; UV radiation resistance-associated gene protein
D PDIP_04560 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family
D PDIP_56870 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family
D PDIP_16140 Amino acid transporter, putative K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D PDIP_51780 Phosphatidylinositol 3,5-bisphosphate-binding protein, putative K22991 WDR45; WD repeat-containing protein 45
D PDIP_00350 Vacuolar ATPase assembly integral membrane protein VMA21 K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
D PDIP_55290 hypothetical protein K27411 PHAF1; phagosome assembly factor 1
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D PDIP_45820 NADPH oxidase (NoxA), putative K08008 NOX1; NADPH oxidase 1
C Nox associated proteins
D PDIP_00590 hypothetical protein K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D PDIP_03310 Myosin I MyoA/Myo5 K10356 MYO1; myosin I
D PDIP_22230 Class V myosin (Myo4), putative K10357 MYO5; myosin V
C Arp2/3 complex
D PDIP_68280 Actin-related protein 2/3 complex subunit 1A, putative K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D PDIP_10460 hypothetical protein K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D PDIP_47750 hypothetical protein K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D PDIP_62010 ARP2/3 complex 20 kDa subunit (P20-ARC), putative K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D PDIP_74910 Actin-related protein 2/3 complex subunit 5 K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D PDIP_27720 Actin-like protein, putative K17260 ACTR2; actin-related protein 2
D PDIP_60290 Arp2/3 complex subunit (Arp3), putative K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D PDIP_61790 Proline-rich protein LAS17 K23612 WASL; neural Wiskott-Aldrich syndrome protein
D PDIP_42050 Actin binding protein, putative K20520 DBNL; drebrin-like protein
D PDIP_82950 Actin cytoskeleton-regulatory complex protein PAN1 K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D PDIP_24490 BAR adaptor protein, putative K12562 AMPH; amphiphysin
D PDIP_01950 Cytoskeleton assembly control protein Sla1, putative K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D PDIP_64330 hypothetical protein K20521 BBC1; myosin tail region-interacting protein MTI1
D PDIP_08790 hypothetical protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D PDIP_36830 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D PDIP_53600 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D PDIP_35740 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D PDIP_79310 Phosphatidylinositol 4-kinase type II subunit alpha, putative K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D PDIP_08390 Profilin K05759 PFN; profilin
D PDIP_77530 Profilin K05759 PFN; profilin
D PDIP_12740 hypothetical protein K05765 CFL; cofilin
D PDIP_35310 hypothetical protein K05765 CFL; cofilin
D PDIP_57600 Cofilin K05765 CFL; cofilin
D PDIP_28190 Adenylyl cyclase-associated protein K17261 CAP1_2; adenylyl cyclase-associated protein
D PDIP_46500 Kinesin family protein (KinA), putative K10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]
D PDIP_44320 Calponin domain protein K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B MARVEL domain-containing proteins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
D PDIP_69440 Inositol phospholipid biosynthesis protein Scs3, putative K28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D PDIP_00570 Rho GTPase activator (Rgd1), putative K20643 RGD1; Rho GTPase-activating protein RGD1
D PDIP_68170 Rho GTPase activator (Bem3), putative K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D PDIP_58460 Rho guanyl nucleotide exchange factor, putative K20705 DNMBP; dynamin-binding protein
D PDIP_20870 hypothetical protein K05727 DOCK3; dedicator of cytokinesis protein 3
D PDIP_15010 GTP binding protein, putative K27817 RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1
D PDIP_05500 hypothetical protein K28415 DENND11; DENN domain-containing protein 11
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: September 19, 2025